Danio rerio

22 known processes

pufa

PUF (Pumilio/FBF) domain-containing A

(Aliases: zgc:66377,SMC5L1,MGC66377)

pufa biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of camp biosynthetic process GO:0030817 9 0.129
maintenance of location GO:0051235 4 0.123
positive regulation of camp biosynthetic process GO:0030819 2 0.108
brain development GO:0007420 293 0.107
regulation of inflammatory response GO:0050727 2 0.084
cellular aromatic compound metabolic process GO:0006725 295 0.080
organic substance biosynthetic process GO:1901576 289 0.071
gene expression GO:0010467 252 0.070
nitrogen compound metabolic process GO:0006807 319 0.069
response to chemical GO:0042221 320 0.059
biosynthetic process GO:0009058 294 0.056
organic cyclic compound biosynthetic process GO:1901362 223 0.055
organonitrogen compound metabolic process GO:1901564 74 0.054
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.051
regulation of cell communication GO:0010646 232 0.050
regionalization GO:0003002 274 0.049
immune system process GO:0002376 241 0.049
signal transduction GO:0007165 455 0.049
regulation of cyclic nucleotide biosynthetic process GO:0030802 15 0.048
nucleobase containing compound biosynthetic process GO:0034654 205 0.047
lipid storage GO:0019915 1 0.046
cellular biosynthetic process GO:0044249 286 0.046
heterocycle metabolic process GO:0046483 290 0.045
morphogenesis of an epithelium GO:0002009 333 0.043
organic cyclic compound metabolic process GO:1901360 301 0.043
cellular ketone metabolic process GO:0042180 11 0.043
cognition GO:0050890 1 0.041
nucleobase containing compound metabolic process GO:0006139 274 0.041
pole plasm assembly GO:0007315 4 0.040
cell surface receptor signaling pathway GO:0007166 325 0.040
cellular nitrogen compound metabolic process GO:0034641 290 0.040
larval development GO:0002164 2 0.039
single organism biosynthetic process GO:0044711 71 0.039
purine nucleotide biosynthetic process GO:0006164 20 0.038
aging GO:0007568 2 0.038
phosphorus metabolic process GO:0006793 109 0.037
hemopoiesis GO:0030097 183 0.036
regulation of synapse assembly GO:0051963 3 0.036
regulation of signal transduction GO:0009966 225 0.036
head development GO:0060322 303 0.035
rna metabolic process GO:0016070 219 0.034
camp biosynthetic process GO:0006171 11 0.034
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.034
cellular nitrogen compound biosynthetic process GO:0044271 218 0.034
regulation of nucleic acid templated transcription GO:1903506 213 0.033
small molecule metabolic process GO:0044281 77 0.032
phosphorylation GO:0016310 69 0.032
regulation of signaling GO:0023051 235 0.032
oocyte anterior posterior axis specification GO:0007314 4 0.032
rna localization GO:0006403 4 0.032
regulation of reproductive process GO:2000241 4 0.032
locomotion GO:0040011 313 0.032
regulation of synapse organization GO:0050807 3 0.031
amine metabolic process GO:0009308 2 0.031
regulation of cellular amine metabolic process GO:0033238 0 0.031
regulation of cellular biosynthetic process GO:0031326 245 0.030
nucleic acid templated transcription GO:0097659 181 0.030
cation homeostasis GO:0055080 33 0.030
aromatic compound biosynthetic process GO:0019438 217 0.029
synaptic growth at neuromuscular junction GO:0051124 2 0.028
transcription dna templated GO:0006351 181 0.028
regulation of biological quality GO:0065008 263 0.027
response to drug GO:0042493 3 0.027
ribose phosphate biosynthetic process GO:0046390 20 0.027
positive regulation of cell activation GO:0050867 1 0.026
cytoplasm organization GO:0007028 4 0.026
central nervous system development GO:0007417 387 0.026
cellular component movement GO:0006928 335 0.025
cellular protein metabolic process GO:0044267 129 0.025
positive regulation of catabolic process GO:0009896 4 0.025
neuron differentiation GO:0030182 353 0.025
cellular macromolecule metabolic process GO:0044260 391 0.025
organic acid metabolic process GO:0006082 31 0.024
regulation of macromolecule metabolic process GO:0060255 317 0.024
organonitrogen compound biosynthetic process GO:1901566 47 0.024
regulation of cellular amino acid metabolic process GO:0006521 0 0.024
adherens junction organization GO:0034332 4 0.024
alcohol biosynthetic process GO:0046165 2 0.024
embryo development ending in birth or egg hatching GO:0009792 271 0.024
cell cycle GO:0007049 93 0.024
cellular amine metabolic process GO:0044106 2 0.024
positive regulation of purine nucleotide biosynthetic process GO:1900373 8 0.023
regulation of cellular ketone metabolic process GO:0010565 7 0.023
ribonucleotide biosynthetic process GO:0009260 20 0.023
regulation of metabolic process GO:0019222 359 0.022
hematopoietic or lymphoid organ development GO:0048534 191 0.022
positive regulation of camp metabolic process GO:0030816 2 0.022
multi organism process GO:0051704 134 0.022
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.022
negative regulation of biological process GO:0048519 304 0.021
regulation of cyclic nucleotide metabolic process GO:0030799 15 0.021
spermatid differentiation GO:0048515 2 0.021
oxoacid metabolic process GO:0043436 31 0.021
positive regulation of cellular catabolic process GO:0031331 3 0.021
carboxylic acid metabolic process GO:0019752 22 0.021
microtubule based process GO:0007017 60 0.021
regulation of cytoplasmic transport GO:1903649 4 0.021
positive regulation of biological process GO:0048518 253 0.020
sequestering of calcium ion GO:0051208 3 0.020
digestive tract development GO:0048565 265 0.020
regulation of rna biosynthetic process GO:2001141 213 0.020
multicellular organism growth GO:0035264 4 0.020
organelle organization GO:0006996 227 0.020
embryonic organ morphogenesis GO:0048562 274 0.020
response to alkaloid GO:0043279 2 0.020
single organism metabolic process GO:0044710 217 0.020
regulation of purine nucleotide biosynthetic process GO:1900371 15 0.020
nucleoside phosphate biosynthetic process GO:1901293 21 0.020
positive regulation of cell cycle GO:0045787 3 0.020
cyclic nucleotide biosynthetic process GO:0009190 18 0.020
positive regulation of cellular process GO:0048522 201 0.020
tube morphogenesis GO:0035239 349 0.019
embryonic organ development GO:0048568 381 0.019
cellular amino acid metabolic process GO:0006520 7 0.019
cytokinesis GO:0000910 3 0.019
cellular response to external stimulus GO:0071496 2 0.019
female gonad development GO:0008585 4 0.019
regulation of metal ion transport GO:0010959 4 0.019
development of primary female sexual characteristics GO:0046545 4 0.018
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.018
negative regulation of synapse assembly GO:0051964 2 0.018
release of sequestered calcium ion into cytosol GO:0051209 3 0.018
rna biosynthetic process GO:0032774 181 0.018
transcription from rna polymerase ii promoter GO:0006366 80 0.018
ribonucleotide metabolic process GO:0009259 27 0.018
regulation of phosphorus metabolic process GO:0051174 43 0.018
regulation of nitrogen compound metabolic process GO:0051171 251 0.018
developmental maturation GO:0021700 34 0.018
cell projection morphogenesis GO:0048858 244 0.017
programmed cell death GO:0012501 119 0.017
generation of neurons GO:0048699 385 0.017
regulation of cytokine production GO:0001817 3 0.017
regulation of cellular metabolic process GO:0031323 320 0.017
regulation of primary metabolic process GO:0080090 311 0.017
cyclic purine nucleotide metabolic process GO:0052652 18 0.017
regulation of cell activation GO:0050865 1 0.016
tyrosine phosphorylation of stat protein GO:0007260 1 0.016
protein metabolic process GO:0019538 183 0.016
regulation of epithelial cell proliferation GO:0050678 3 0.016
calcium ion transport into cytosol GO:0060402 3 0.016
microtubule cytoskeleton organization GO:0000226 33 0.016
protein localization to nucleus GO:0034504 3 0.016
regulation of camp metabolic process GO:0030814 9 0.016
cell part morphogenesis GO:0032990 246 0.016
positive regulation of cell division GO:0051781 2 0.016
chemosensory behavior GO:0007635 1 0.016
positive regulation of nucleotide biosynthetic process GO:0030810 8 0.016
regulation of biosynthetic process GO:0009889 250 0.016
regulation of protein localization to nucleus GO:1900180 2 0.016
regulation of multicellular organism growth GO:0040014 4 0.016
nucleic acid metabolic process GO:0090304 244 0.015
actin polymerization or depolymerization GO:0008154 2 0.015
macromolecule biosynthetic process GO:0009059 227 0.015
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.015
interspecies interaction between organisms GO:0044419 4 0.015
organelle localization GO:0051640 49 0.015
stem cell maintenance GO:0019827 4 0.015
positive regulation of cellular metabolic process GO:0031325 94 0.015
response to organic substance GO:0010033 153 0.015
negative regulation of cellular process GO:0048523 283 0.015
neuron development GO:0048666 262 0.015
regulation of protein catabolic process GO:0042176 1 0.015
female sex differentiation GO:0046660 4 0.015
reproduction GO:0000003 40 0.014
regulation of stem cell proliferation GO:0072091 2 0.014
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.014
regulation of gene expression GO:0010468 265 0.014
cellular macromolecule biosynthetic process GO:0034645 224 0.014
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.014
cellular protein modification process GO:0006464 100 0.014
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.014
single organism localization GO:1902578 225 0.014
gamete generation GO:0007276 33 0.014
single organism organelle organization GO:1902589 199 0.014
fat soluble vitamin metabolic process GO:0006775 4 0.014
regulation of response to stimulus GO:0048583 269 0.014
digestive system development GO:0055123 289 0.014
meiotic cell cycle process GO:1903046 3 0.014
digestive tract morphogenesis GO:0048546 231 0.014
anterior posterior pattern specification GO:0009952 152 0.014
phosphate containing compound metabolic process GO:0006796 108 0.013
antimicrobial humoral response GO:0019730 2 0.013
sequestering of metal ion GO:0051238 3 0.013
intracellular signal transduction GO:0035556 85 0.013
cellular response to oxygen levels GO:0071453 1 0.013
protein localization to cell surface GO:0034394 3 0.013
purine containing compound metabolic process GO:0072521 29 0.013
negative regulation of sequestering of calcium ion GO:0051283 4 0.013
response to oxygen containing compound GO:1901700 55 0.013
regulation of mrna processing GO:0050684 3 0.013
ribonucleoside monophosphate catabolic process GO:0009158 4 0.013
positive regulation of apoptotic signaling pathway GO:2001235 1 0.013
establishment of endothelial barrier GO:0061028 3 0.013
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.013
leukocyte proliferation GO:0070661 1 0.013
multicellular organismal signaling GO:0035637 22 0.013
ovulation cycle GO:0042698 2 0.013
proteasomal protein catabolic process GO:0010498 2 0.013
cyclic nucleotide metabolic process GO:0009187 18 0.013
hormone secretion GO:0046879 2 0.013
multicellular organismal reproductive process GO:0048609 35 0.013
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.013
cytosolic calcium ion transport GO:0060401 3 0.012
determination of bilateral symmetry GO:0009855 204 0.012
ribose phosphate metabolic process GO:0019693 27 0.012
cellular response to biotic stimulus GO:0071216 3 0.012
response to endogenous stimulus GO:0009719 83 0.012
single organism reproductive process GO:0044702 40 0.012
response to other organism GO:0051707 97 0.012
taxis GO:0042330 109 0.012
zymogen activation GO:0031638 3 0.012
wnt signaling pathway GO:0016055 80 0.012
ion transport GO:0006811 114 0.012
embryonic skeletal system morphogenesis GO:0048704 93 0.012
cellular component morphogenesis GO:0032989 336 0.012
neuroblast proliferation GO:0007405 2 0.012
rna stabilization GO:0043489 4 0.012
nuclear transport GO:0051169 4 0.012
response to metal ion GO:0010038 34 0.012
cellular protein catabolic process GO:0044257 4 0.012
establishment of protein localization to organelle GO:0072594 4 0.012
regulation of transcription dna templated GO:0006355 213 0.011
sexual reproduction GO:0019953 36 0.011
cortical actin cytoskeleton organization GO:0030866 1 0.011
calcium mediated signaling GO:0019722 2 0.011
spermatid development GO:0007286 2 0.011
guanosine containing compound metabolic process GO:1901068 4 0.011
chemical homeostasis GO:0048878 49 0.011
regulation of nucleotide biosynthetic process GO:0030808 15 0.011
protein import GO:0017038 3 0.011
regulation of intracellular protein transport GO:0033157 3 0.011
maternal determination of anterior posterior axis embryo GO:0008358 4 0.011
growth GO:0040007 174 0.011
homeostatic process GO:0042592 142 0.011
protein modification process GO:0036211 100 0.011
action potential GO:0001508 19 0.011
neurological system process GO:0050877 62 0.011
segmentation GO:0035282 97 0.011
cytoskeleton organization GO:0007010 96 0.011
response to amine GO:0014075 1 0.011
developmental growth GO:0048589 166 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
meiotic nuclear division GO:0007126 4 0.011
behavior GO:0007610 74 0.011
long chain fatty acid metabolic process GO:0001676 1 0.011
negative regulation of response to stimulus GO:0048585 104 0.011
energy reserve metabolic process GO:0006112 2 0.011
carbohydrate derivative biosynthetic process GO:1901137 43 0.011
response to monosaccharide GO:0034284 3 0.011
gtp metabolic process GO:0046039 4 0.011
response to carbohydrate GO:0009743 3 0.011
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.011
negative regulation of epithelial cell proliferation GO:0050680 1 0.011
g protein coupled receptor signaling pathway GO:0007186 74 0.011
neuron projection morphogenesis GO:0048812 161 0.010
nuclear import GO:0051170 3 0.010
cell morphogenesis GO:0000902 289 0.010
protein targeting to nucleus GO:0044744 3 0.010
regulation of nucleotide metabolic process GO:0006140 17 0.010
modification dependent macromolecule catabolic process GO:0043632 3 0.010
response to amino acid GO:0043200 2 0.010
cell projection organization GO:0030030 284 0.010
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.010
positive regulation of metabolic process GO:0009893 108 0.010
negative regulation of multi organism process GO:0043901 3 0.010
intracellular mrna localization GO:0008298 1 0.010
response to lipid GO:0033993 60 0.010
positive regulation of translation GO:0045727 1 0.010
mrna stabilization GO:0048255 4 0.010
positive regulation of nucleotide catabolic process GO:0030813 1 0.010
regulation of neuronal synaptic plasticity GO:0048168 1 0.010
chromosome organization GO:0051276 31 0.010
regulation of protein targeting GO:1903533 2 0.010
modification dependent protein catabolic process GO:0019941 3 0.010
guanosine containing compound catabolic process GO:1901069 2 0.010

pufa disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.039
sensory system disease DOID:0050155 0 0.023
eye and adnexa disease DOID:1492 0 0.023
nervous system disease DOID:863 0 0.023
eye disease DOID:5614 0 0.018
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
retinal disease DOID:5679 0 0.013
immune system disease DOID:2914 0 0.013
hematopoietic system disease DOID:74 0 0.013