Danio rerio

20 known processes

itgb8

integrin, beta 8

(Aliases: si:ch1073-83d9.2)

itgb8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
signal transduction GO:0007165 455 0.061
cellular macromolecule metabolic process GO:0044260 391 0.042
larval development GO:0002164 2 0.042
cellular carbohydrate metabolic process GO:0044262 4 0.039
sensory organ development GO:0007423 393 0.039
cellular aromatic compound metabolic process GO:0006725 295 0.035
head development GO:0060322 303 0.035
cellular nitrogen compound metabolic process GO:0034641 290 0.035
positive regulation of transport GO:0051050 2 0.034
cellular biosynthetic process GO:0044249 286 0.034
response to chemical GO:0042221 320 0.032
cell projection morphogenesis GO:0048858 244 0.032
regulation of signaling GO:0023051 235 0.032
heterocycle biosynthetic process GO:0018130 215 0.031
aging GO:0007568 2 0.031
cell surface receptor signaling pathway GO:0007166 325 0.031
macromolecule biosynthetic process GO:0009059 227 0.030
cellular macromolecule biosynthetic process GO:0034645 224 0.030
heterocycle metabolic process GO:0046483 290 0.030
establishment of protein localization to organelle GO:0072594 4 0.030
organic substance biosynthetic process GO:1901576 289 0.030
nucleobase containing compound biosynthetic process GO:0034654 205 0.030
regulation of primary metabolic process GO:0080090 311 0.029
nucleobase containing compound metabolic process GO:0006139 274 0.029
embryonic organ morphogenesis GO:0048562 274 0.028
regulation of autophagy GO:0010506 3 0.028
actin polymerization or depolymerization GO:0008154 2 0.028
central nervous system development GO:0007417 387 0.028
biosynthetic process GO:0009058 294 0.028
eye development GO:0001654 277 0.027
lipid catabolic process GO:0016042 4 0.027
organic cyclic compound biosynthetic process GO:1901362 223 0.027
phagocytosis GO:0006909 3 0.027
regulation of response to stimulus GO:0048583 269 0.027
cognition GO:0050890 1 0.026
nucleic acid metabolic process GO:0090304 244 0.026
blood vessel development GO:0001568 246 0.026
organic cyclic compound metabolic process GO:1901360 301 0.026
regulation of signal transduction GO:0009966 225 0.025
cellular response to external stimulus GO:0071496 2 0.025
protein localization to nucleus GO:0034504 3 0.025
autophagy GO:0006914 4 0.024
regulation of protein complex assembly GO:0043254 3 0.024
cellular component morphogenesis GO:0032989 336 0.024
regulation of neural precursor cell proliferation GO:2000177 3 0.024
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.024
positive regulation of catabolic process GO:0009896 4 0.024
cell morphogenesis GO:0000902 289 0.024
regulation of synapse assembly GO:0051963 3 0.023
positive regulation of cellular catabolic process GO:0031331 3 0.023
regulation of protein localization to nucleus GO:1900180 2 0.023
regulation of cellular metabolic process GO:0031323 320 0.023
maintenance of location GO:0051235 4 0.023
cellular response to chemical stimulus GO:0070887 157 0.023
single organism metabolic process GO:0044710 217 0.023
regulation of multicellular organism growth GO:0040014 4 0.023
regulation of cell communication GO:0010646 232 0.023
angiogenesis GO:0001525 158 0.022
cellular response to extracellular stimulus GO:0031668 2 0.022
regulation of metabolic process GO:0019222 359 0.022
rna biosynthetic process GO:0032774 181 0.022
anterior posterior pattern specification GO:0009952 152 0.022
regulation of carbohydrate metabolic process GO:0006109 4 0.022
transcription dna templated GO:0006351 181 0.022
multicellular organism growth GO:0035264 4 0.022
positive regulation of cell cycle GO:0045787 3 0.022
cell part morphogenesis GO:0032990 246 0.022
cellular nitrogen compound biosynthetic process GO:0044271 218 0.022
regulation of cellular biosynthetic process GO:0031326 245 0.022
regulation of protein transport GO:0051223 3 0.021
aromatic compound biosynthetic process GO:0019438 217 0.021
morphogenesis of an epithelium GO:0002009 333 0.021
synaptic growth at neuromuscular junction GO:0051124 2 0.021
negative regulation of biological process GO:0048519 304 0.021
regulation of nitrogen compound metabolic process GO:0051171 251 0.021
positive regulation of cellular component biogenesis GO:0044089 3 0.021
regulation of stem cell proliferation GO:0072091 2 0.021
ubiquitin dependent protein catabolic process GO:0006511 3 0.021
cellular response to starvation GO:0009267 1 0.021
tube morphogenesis GO:0035239 349 0.020
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.020
stem cell proliferation GO:0072089 4 0.020
rna metabolic process GO:0016070 219 0.020
regionalization GO:0003002 274 0.020
brain development GO:0007420 293 0.020
regulation of biosynthetic process GO:0009889 250 0.020
cell motility GO:0048870 244 0.020
golgi vesicle transport GO:0048193 3 0.019
cellular protein catabolic process GO:0044257 4 0.019
peptidyl lysine acetylation GO:0018394 2 0.019
cellular amine metabolic process GO:0044106 2 0.019
response to drug GO:0042493 3 0.019
nitrogen compound metabolic process GO:0006807 319 0.019
regulation of transcription dna templated GO:0006355 213 0.019
response to carbohydrate GO:0009743 3 0.019
protein acetylation GO:0006473 2 0.019
protein import GO:0017038 3 0.019
lipid storage GO:0019915 1 0.019
negative regulation of cellular process GO:0048523 283 0.019
mononuclear cell proliferation GO:0032943 1 0.019
cellular component movement GO:0006928 335 0.019
regulation of reproductive process GO:2000241 4 0.019
regulation of cellular amine metabolic process GO:0033238 0 0.019
positive regulation of cytoskeleton organization GO:0051495 3 0.019
neuroblast proliferation GO:0007405 2 0.019
negative regulation of synapse assembly GO:0051964 2 0.019
regulation of cellular amino acid metabolic process GO:0006521 0 0.018
generation of neurons GO:0048699 385 0.018
stem cell maintenance GO:0019827 4 0.018
locomotion GO:0040011 313 0.018
protein targeting to nucleus GO:0044744 3 0.018
regulation of nucleic acid templated transcription GO:1903506 213 0.018
regulation of cytokine production GO:0001817 3 0.018
regulation of biological quality GO:0065008 263 0.018
embryonic organ development GO:0048568 381 0.018
extrinsic apoptotic signaling pathway GO:0097191 3 0.018
regulation of rna metabolic process GO:0051252 224 0.018
negative regulation of protein phosphorylation GO:0001933 4 0.018
regulation of synapse organization GO:0050807 3 0.018
gene expression GO:0010467 252 0.018
regulation of protein catabolic process GO:0042176 1 0.018
amine metabolic process GO:0009308 2 0.018
regulation of establishment of protein localization GO:0070201 4 0.018
chemosensory behavior GO:0007635 1 0.018
positive regulation of biological process GO:0048518 253 0.018
leukocyte proliferation GO:0070661 1 0.018
regulation of ion transmembrane transporter activity GO:0032412 2 0.018
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.017
development of primary female sexual characteristics GO:0046545 4 0.017
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.017
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.017
cell substrate adhesion GO:0031589 4 0.017
modification dependent macromolecule catabolic process GO:0043632 3 0.017
internal protein amino acid acetylation GO:0006475 2 0.017
regulation of cellular ketone metabolic process GO:0010565 7 0.017
female gonad development GO:0008585 4 0.017
cell migration GO:0016477 237 0.017
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.017
regulation of multicellular organismal process GO:0051239 277 0.017
regulation of cell activation GO:0050865 1 0.017
transport GO:0006810 220 0.017
regulation of binding GO:0051098 3 0.017
phosphatidylinositol mediated signaling GO:0048015 2 0.017
modification dependent protein catabolic process GO:0019941 3 0.017
regulation of cytoplasmic transport GO:1903649 4 0.017
peptide transport GO:0015833 1 0.017
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.017
lateral inhibition GO:0046331 1 0.017
regulation of synaptic plasticity GO:0048167 1 0.017
regulation of metal ion transport GO:0010959 4 0.017
cellular amide metabolic process GO:0043603 4 0.017
wnt signaling pathway GO:0016055 80 0.017
glucose homeostasis GO:0042593 1 0.017
hormone secretion GO:0046879 2 0.017
single organism nuclear import GO:1902593 3 0.016
neuron differentiation GO:0030182 353 0.016
response to monosaccharide GO:0034284 3 0.016
vasculature development GO:0001944 278 0.016
nucleic acid templated transcription GO:0097659 181 0.016
neurotransmitter transport GO:0006836 2 0.016
olfactory lobe development GO:0021988 4 0.016
nuclear transport GO:0051169 4 0.016
cellular lipid catabolic process GO:0044242 3 0.016
proteasomal protein catabolic process GO:0010498 2 0.016
muscle structure development GO:0061061 196 0.016
energy reserve metabolic process GO:0006112 2 0.016
response to hexose GO:0009746 3 0.016
response to organic substance GO:0010033 153 0.016
regulation of intracellular protein transport GO:0033157 3 0.016
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.016
nucleocytoplasmic transport GO:0006913 4 0.016
positive regulation of protein complex assembly GO:0031334 2 0.016
female sex differentiation GO:0046660 4 0.016
oxoacid metabolic process GO:0043436 31 0.016
regulation of sequestering of calcium ion GO:0051282 4 0.016
regulation of blood vessel size GO:0050880 2 0.016
cell projection organization GO:0030030 284 0.016
digestive system development GO:0055123 289 0.016
cellular response to nutrient levels GO:0031669 2 0.015
synaptic vesicle localization GO:0097479 1 0.015
gtp catabolic process GO:0006184 2 0.015
regulation of multicellular organismal development GO:2000026 223 0.015
macroautophagy GO:0016236 1 0.015
synaptic vesicle transport GO:0048489 1 0.015
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.015
tube closure GO:0060606 1 0.015
regulation of gene expression GO:0010468 265 0.015
negative regulation of catabolic process GO:0009895 3 0.015
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.015
mitochondrion organization GO:0007005 4 0.015
i kappab kinase nf kappab signaling GO:0007249 4 0.015
response to glucose GO:0009749 3 0.015
ear development GO:0043583 127 0.015
single organism organelle organization GO:1902589 199 0.015
cellular component disassembly GO:0022411 1 0.015
adult behavior GO:0030534 2 0.015
organic acid metabolic process GO:0006082 31 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.015
positive regulation of secretion by cell GO:1903532 1 0.015
response to external stimulus GO:0009605 264 0.015
internal peptidyl lysine acetylation GO:0018393 2 0.015
ribonucleoside monophosphate catabolic process GO:0009158 4 0.015
carboxylic acid metabolic process GO:0019752 22 0.015
chordate embryonic development GO:0043009 271 0.015
regulation of cell substrate adhesion GO:0010810 1 0.015
homeostatic process GO:0042592 142 0.015
protein acylation GO:0043543 3 0.015
inositol lipid mediated signaling GO:0048017 2 0.015
cellular ketone metabolic process GO:0042180 11 0.015
meiotic nuclear division GO:0007126 4 0.014
regulation of inflammatory response GO:0050727 2 0.014
heart development GO:0007507 313 0.014
regulation of developmental process GO:0050793 247 0.014
sympathetic nervous system development GO:0048485 3 0.014
secondary metabolic process GO:0019748 3 0.014
epithelial tube morphogenesis GO:0060562 148 0.014
response to nutrient GO:0007584 3 0.014
regulation of epithelial cell proliferation GO:0050678 3 0.014
regulation of nucleocytoplasmic transport GO:0046822 2 0.014
regulation of mrna processing GO:0050684 3 0.014
signal transduction in absence of ligand GO:0038034 1 0.014
establishment of synaptic vesicle localization GO:0097480 1 0.014
regulation of meiotic cell cycle GO:0051445 1 0.014
protein homooligomerization GO:0051260 3 0.014
carbohydrate biosynthetic process GO:0016051 1 0.014
digestive tract development GO:0048565 265 0.014
protein localization to plasma membrane GO:0072659 1 0.014
positive regulation of secretion GO:0051047 1 0.014
cell morphogenesis involved in differentiation GO:0000904 195 0.014
positive regulation of glucose import GO:0046326 1 0.014
protein polymerization GO:0051258 4 0.014
embryonic skeletal system development GO:0048706 97 0.014
striated muscle cell differentiation GO:0051146 129 0.014
determination of bilateral symmetry GO:0009855 204 0.014
regulation of macromolecule metabolic process GO:0060255 317 0.014
cellular response to oxygen levels GO:0071453 1 0.014
positive regulation of apoptotic signaling pathway GO:2001235 1 0.014
positive regulation of blood circulation GO:1903524 2 0.014
transcription from rna polymerase ii promoter GO:0006366 80 0.014
inner ear development GO:0048839 126 0.014
nuclear import GO:0051170 3 0.014
organelle organization GO:0006996 227 0.014
localization of cell GO:0051674 244 0.014
centrosome organization GO:0051297 1 0.014
embryonic heart tube morphogenesis GO:0003143 108 0.014
lymphocyte proliferation GO:0046651 1 0.014
positive regulation of cellular process GO:0048522 201 0.014
sensory organ morphogenesis GO:0090596 200 0.014
positive regulation of cell activation GO:0050867 1 0.014
protein metabolic process GO:0019538 183 0.014
hormone transport GO:0009914 2 0.013
establishment of localization GO:0051234 244 0.013
guanosine containing compound metabolic process GO:1901068 4 0.013
protein import into nucleus GO:0006606 3 0.013
cell matrix adhesion GO:0007160 4 0.013
regulation of cell shape GO:0008360 1 0.013
regulation of macromolecule biosynthetic process GO:0010556 225 0.013
outflow tract morphogenesis GO:0003151 1 0.013
mechanosensory behavior GO:0007638 2 0.013
exocytosis GO:0006887 1 0.013
system process GO:0003008 185 0.013
actin filament polymerization GO:0030041 2 0.013
carbohydrate homeostasis GO:0033500 1 0.013
small molecule catabolic process GO:0044282 3 0.013
hatching GO:0035188 4 0.013
regulation of protein targeting GO:1903533 2 0.013
organism emergence from protective structure GO:0071684 4 0.013
organonitrogen compound metabolic process GO:1901564 74 0.013
regulation of transmembrane transporter activity GO:0022898 2 0.013
convergent extension GO:0060026 118 0.013
guanosine containing compound catabolic process GO:1901069 2 0.013
neurotransmitter secretion GO:0007269 2 0.013
regulation of protein polymerization GO:0032271 2 0.013
regulation of tube size GO:0035150 2 0.013
heart looping GO:0001947 94 0.013
positive regulation of epithelial cell migration GO:0010634 2 0.013
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.013
regulation of rna biosynthetic process GO:2001141 213 0.013
specification of symmetry GO:0009799 204 0.012
regulation of protein import into nucleus GO:0042306 2 0.012
protein complex disassembly GO:0043241 1 0.012
nucleoside monophosphate catabolic process GO:0009125 4 0.012
atp catabolic process GO:0006200 4 0.012
intracellular signal transduction GO:0035556 85 0.012
regulation of circadian rhythm GO:0042752 4 0.012
gtp metabolic process GO:0046039 4 0.012
positive regulation of immune effector process GO:0002699 3 0.012
negative regulation of cytoplasmic transport GO:1903650 2 0.012
response to glucocorticoid GO:0051384 1 0.012
macromolecular complex disassembly GO:0032984 1 0.012
transmission of nerve impulse GO:0019226 19 0.012
fertilization GO:0009566 3 0.012
negative regulation of dna metabolic process GO:0051053 4 0.012
response to topologically incorrect protein GO:0035966 2 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.012
cellular component biogenesis GO:0044085 178 0.012
cellular response to organic substance GO:0071310 105 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.012
locomotor rhythm GO:0045475 3 0.012
mesenchyme development GO:0060485 127 0.012
microtubule organizing center organization GO:0031023 1 0.012
rna localization GO:0006403 4 0.012
regulation of cell projection assembly GO:0060491 4 0.012
meiotic cell cycle process GO:1903046 3 0.012
positive regulation of reproductive process GO:2000243 2 0.012
response to uv GO:0009411 3 0.012
skeletal system development GO:0001501 181 0.012
production of molecular mediator of immune response GO:0002440 2 0.012
negative regulation of protein localization to nucleus GO:1900181 2 0.012
cellular response to hypoxia GO:0071456 1 0.012
cytoplasm organization GO:0007028 4 0.012
regulation of organelle assembly GO:1902115 4 0.012
multicellular organismal signaling GO:0035637 22 0.011
axonogenesis GO:0007409 152 0.011
post golgi vesicle mediated transport GO:0006892 1 0.011
cell cycle g1 s phase transition GO:0044843 1 0.011
camera type eye development GO:0043010 222 0.011
sleep GO:0030431 1 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
blood vessel morphogenesis GO:0048514 216 0.011
negative regulation of sequestering of calcium ion GO:0051283 4 0.011
membrane invagination GO:0010324 1 0.011
carboxylic acid catabolic process GO:0046395 3 0.011
regulation of transporter activity GO:0032409 2 0.011
regulation of cell differentiation GO:0045595 142 0.011
regulation of response to biotic stimulus GO:0002831 2 0.011
regulation of dendrite development GO:0050773 3 0.011
protein stabilization GO:0050821 2 0.011
regulation of bone mineralization GO:0030500 2 0.011
gland development GO:0048732 143 0.011
cytokinesis GO:0000910 3 0.011
regulation of dna replication GO:0006275 3 0.011
neuron projection development GO:0031175 180 0.011
neuron projection morphogenesis GO:0048812 161 0.011
enzyme linked receptor protein signaling pathway GO:0007167 106 0.011
adherens junction organization GO:0034332 4 0.011
dorsal ventral pattern formation GO:0009953 125 0.011
negative regulation of response to stimulus GO:0048585 104 0.011
cellular response to reactive oxygen species GO:0034614 2 0.011
pancreas development GO:0031016 84 0.011
nuclear migration GO:0007097 3 0.011
neuron development GO:0048666 262 0.011
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.011
positive regulation of metabolic process GO:0009893 108 0.011
regulation of stem cell differentiation GO:2000736 4 0.011
single organism localization GO:1902578 225 0.011
regulation of reactive oxygen species metabolic process GO:2000377 2 0.011
neuron neuron synaptic transmission GO:0007270 1 0.011
compound eye development GO:0048749 2 0.011
regulation of hormone secretion GO:0046883 2 0.011
cellular amino acid metabolic process GO:0006520 7 0.011
gastrulation GO:0007369 208 0.011
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.011
protein heterooligomerization GO:0051291 1 0.011
sequestering of metal ion GO:0051238 3 0.011
establishment of protein localization to plasma membrane GO:0090002 1 0.011
immune system process GO:0002376 241 0.011
response to transition metal nanoparticle GO:1990267 28 0.011
regulation of production of molecular mediator of immune response GO:0002700 1 0.011
protein secretion GO:0009306 1 0.011
gas transport GO:0015669 3 0.011
regulation of nucleoside metabolic process GO:0009118 2 0.011
catechol containing compound metabolic process GO:0009712 2 0.011
positive regulation of histone modification GO:0031058 1 0.010
intracellular mrna localization GO:0008298 1 0.010
single organism biosynthetic process GO:0044711 71 0.010
negative regulation of epithelial cell proliferation GO:0050680 1 0.010
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.010
single fertilization GO:0007338 3 0.010
g protein coupled receptor signaling pathway GO:0007186 74 0.010
cell death GO:0008219 121 0.010
interspecies interaction between organisms GO:0044419 4 0.010
small molecule metabolic process GO:0044281 77 0.010
negative regulation of intracellular transport GO:0032387 3 0.010
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.010
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.010
cellular response to decreased oxygen levels GO:0036294 1 0.010
response to corticosteroid GO:0031960 1 0.010
lamellipodium organization GO:0097581 1 0.010
positive regulation of nucleotide catabolic process GO:0030813 1 0.010
regulation of wnt signaling pathway GO:0030111 53 0.010
negative regulation of cellular catabolic process GO:0031330 3 0.010
g1 s transition of mitotic cell cycle GO:0000082 1 0.010
cilium assembly GO:0042384 58 0.010
negative regulation of defense response GO:0031348 2 0.010
peptidyl threonine phosphorylation GO:0018107 1 0.010
determination of heart left right asymmetry GO:0061371 117 0.010
response to stress GO:0006950 263 0.010
response to abiotic stimulus GO:0009628 122 0.010
negative regulation of cell communication GO:0010648 96 0.010
mitochondrial transport GO:0006839 2 0.010
positive regulation of protein polymerization GO:0032273 2 0.010
membrane fusion GO:0061025 2 0.010

itgb8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.037
cardiovascular system disease DOID:1287 0 0.019
musculoskeletal system disease DOID:17 0 0.018
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
organ system cancer DOID:0050686 0 0.013
myopathy DOID:423 0 0.013
muscular disease DOID:0080000 0 0.013
muscle tissue disease DOID:66 0 0.013
connective tissue disease DOID:65 0 0.011
disease of metabolism DOID:0014667 0 0.010