Danio rerio

27 known processes

cdkn1a

cyclin-dependent kinase inhibitor 1A

(Aliases: si:ch1073-48m5.2)

cdkn1a biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
tube morphogenesis GO:0035239 349 0.331
regulation of cellular metabolic process GO:0031323 320 0.261
generation of neurons GO:0048699 385 0.236
cellular nitrogen compound metabolic process GO:0034641 290 0.229
regulation of mitochondrion organization GO:0010821 1 0.226
central nervous system development GO:0007417 387 0.214
extrinsic apoptotic signaling pathway GO:0097191 3 0.201
heterocycle metabolic process GO:0046483 290 0.196
cellular component biogenesis GO:0044085 178 0.196
positive regulation of cellular component biogenesis GO:0044089 3 0.191
positive regulation of neuron death GO:1901216 1 0.188
cell surface receptor signaling pathway GO:0007166 325 0.186
negative regulation of response to stimulus GO:0048585 104 0.168
regulation of macromolecule biosynthetic process GO:0010556 225 0.161
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.158
developmental growth GO:0048589 166 0.154
cellular response to starvation GO:0009267 1 0.149
organic cyclic compound metabolic process GO:1901360 301 0.148
hematopoietic or lymphoid organ development GO:0048534 191 0.146
signal transduction GO:0007165 455 0.142
regulation of protein complex assembly GO:0043254 3 0.142
cellular aromatic compound metabolic process GO:0006725 295 0.135
cellular ketone metabolic process GO:0042180 11 0.135
positive regulation of neuron apoptotic process GO:0043525 1 0.132
response to organic cyclic compound GO:0014070 51 0.132
sensory organ development GO:0007423 393 0.130
chordate embryonic development GO:0043009 271 0.129
enzyme linked receptor protein signaling pathway GO:0007167 106 0.129
regulation of cellular amino acid metabolic process GO:0006521 0 0.127
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.120
developmental programmed cell death GO:0010623 4 0.117
eye development GO:0001654 277 0.115
gene expression GO:0010467 252 0.115
positive regulation of biological process GO:0048518 253 0.114
response to biotic stimulus GO:0009607 97 0.112
positive regulation of protein complex assembly GO:0031334 2 0.109
cellular response to lipopolysaccharide GO:0071222 3 0.109
regulation of cellular amine metabolic process GO:0033238 0 0.107
negative regulation of multicellular organismal process GO:0051241 69 0.106
positive regulation of transport GO:0051050 2 0.105
negative regulation of biological process GO:0048519 304 0.104
positive regulation of cellular process GO:0048522 201 0.103
cellular response to nutrient levels GO:0031669 2 0.102
regulation of apoptotic process GO:0042981 98 0.101
regulation of multicellular organism growth GO:0040014 4 0.101
regulation of metabolic process GO:0019222 359 0.099
nucleobase containing compound metabolic process GO:0006139 274 0.098
response to chemical GO:0042221 320 0.096
b cell differentiation GO:0030183 1 0.095
digestive system development GO:0055123 289 0.095
cellular response to extracellular stimulus GO:0031668 2 0.090
gland development GO:0048732 143 0.090
regulation of biosynthetic process GO:0009889 250 0.090
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.090
regulation of rna metabolic process GO:0051252 224 0.090
response to abiotic stimulus GO:0009628 122 0.089
mitochondrion organization GO:0007005 4 0.085
tissue remodeling GO:0048771 4 0.083
positive regulation of apoptotic signaling pathway GO:2001235 1 0.082
response to steroid hormone GO:0048545 35 0.082
regulation of cell communication GO:0010646 232 0.082
brain development GO:0007420 293 0.080
hemopoiesis GO:0030097 183 0.078
response to external biotic stimulus GO:0043207 97 0.078
response to external stimulus GO:0009605 264 0.078
programmed cell death GO:0012501 119 0.078
intracellular signal transduction GO:0035556 85 0.077
positive regulation of secretion GO:0051047 1 0.077
rna metabolic process GO:0016070 219 0.076
neuron differentiation GO:0030182 353 0.073
regulation of signal transduction GO:0009966 225 0.072
zymogen activation GO:0031638 3 0.071
positive regulation of secretion by cell GO:1903532 1 0.070
specification of symmetry GO:0009799 204 0.070
cellular response to external stimulus GO:0071496 2 0.070
nucleic acid metabolic process GO:0090304 244 0.069
negative regulation of signal transduction GO:0009968 94 0.068
cellular component assembly GO:0022607 170 0.068
regulation of establishment of protein localization GO:0070201 4 0.068
regulation of macromolecule metabolic process GO:0060255 317 0.067
multicellular organism growth GO:0035264 4 0.067
nitrogen compound metabolic process GO:0006807 319 0.066
regulation of multicellular organismal process GO:0051239 277 0.066
biosynthetic process GO:0009058 294 0.066
regulation of rna biosynthetic process GO:2001141 213 0.066
regulation of protein binding GO:0043393 3 0.066
cytoskeleton dependent cytokinesis GO:0061640 3 0.066
response to stress GO:0006950 263 0.065
aging GO:0007568 2 0.065
negative regulation of mitosis GO:0045839 3 0.064
negative regulation of apoptotic process GO:0043066 55 0.064
epithelial cell differentiation GO:0030855 116 0.064
organelle assembly GO:0070925 110 0.063
cellular response to hormone stimulus GO:0032870 39 0.063
response to ketone GO:1901654 1 0.062
protein metabolic process GO:0019538 183 0.060
female gonad development GO:0008585 4 0.060
organic substance biosynthetic process GO:1901576 289 0.058
cellular amino acid metabolic process GO:0006520 7 0.058
nucleic acid templated transcription GO:0097659 181 0.058
g1 s transition of mitotic cell cycle GO:0000082 1 0.057
regulation of signaling GO:0023051 235 0.057
cellular response to estrogen stimulus GO:0071391 24 0.056
angiogenesis GO:0001525 158 0.055
single organism metabolic process GO:0044710 217 0.055
female sex differentiation GO:0046660 4 0.055
regulation of erk1 and erk2 cascade GO:0070372 4 0.054
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.054
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress GO:0070059 3 0.054
negative regulation of cellular process GO:0048523 283 0.053
positive regulation of cellular amine metabolic process GO:0033240 0 0.053
response to drug GO:0042493 3 0.053
protein secretion GO:0009306 1 0.053
regulation of developmental process GO:0050793 247 0.053
immune system development GO:0002520 191 0.052
cellular response to lipid GO:0071396 39 0.051
digestive tract development GO:0048565 265 0.051
mitochondrion morphogenesis GO:0070584 2 0.051
apoptotic signaling pathway GO:0097190 23 0.050
heterocycle biosynthetic process GO:0018130 215 0.050
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 9 0.050
homeostatic process GO:0042592 142 0.050
transcription from rna polymerase ii promoter GO:0006366 80 0.050
regulation of epithelial cell proliferation GO:0050678 3 0.050
negative regulation of nuclear division GO:0051784 3 0.049
maintenance of location GO:0051235 4 0.047
positive regulation of multicellular organismal process GO:0051240 52 0.047
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.047
regulation of cellular ketone metabolic process GO:0010565 7 0.047
negative regulation of signaling GO:0023057 96 0.046
intrinsic apoptotic signaling pathway GO:0097193 20 0.046
actomyosin structure organization GO:0031032 53 0.046
negative regulation of cell communication GO:0010648 96 0.046
cell matrix adhesion GO:0007160 4 0.046
cytokinesis GO:0000910 3 0.046
regulation of biological quality GO:0065008 263 0.046
pancreas development GO:0031016 84 0.046
cellular nitrogen compound biosynthetic process GO:0044271 218 0.046
negative regulation of developmental growth GO:0048640 9 0.045
modification dependent protein catabolic process GO:0019941 3 0.045
embryonic limb morphogenesis GO:0030326 2 0.045
positive regulation of developmental process GO:0051094 50 0.045
positive regulation of cellular metabolic process GO:0031325 94 0.044
positive regulation of metabolic process GO:0009893 108 0.044
small molecule metabolic process GO:0044281 77 0.044
cellular response to steroid hormone stimulus GO:0071383 31 0.043
cellular response to endogenous stimulus GO:0071495 68 0.043
regulation of nucleic acid templated transcription GO:1903506 213 0.042
gtp metabolic process GO:0046039 4 0.042
response to ionizing radiation GO:0010212 6 0.042
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.042
post embryonic organ development GO:0048569 4 0.041
positive regulation of cellular catabolic process GO:0031331 3 0.041
nucleobase containing compound biosynthetic process GO:0034654 205 0.041
cellular amine metabolic process GO:0044106 2 0.040
regulation of cell proliferation GO:0042127 37 0.040
regulation of jun kinase activity GO:0043506 3 0.040
positive regulation of gene expression GO:0010628 71 0.039
camera type eye development GO:0043010 222 0.039
erk1 and erk2 cascade GO:0070371 4 0.039
ovarian follicle development GO:0001541 2 0.039
positive regulation of inflammatory response GO:0050729 1 0.039
epithelial tube morphogenesis GO:0060562 148 0.039
organonitrogen compound metabolic process GO:1901564 74 0.039
microtubule polymerization or depolymerization GO:0031109 3 0.039
regulation of intracellular signal transduction GO:1902531 57 0.039
leukocyte differentiation GO:0002521 25 0.038
response to food GO:0032094 1 0.038
response to carbohydrate GO:0009743 3 0.038
response to other organism GO:0051707 97 0.038
protein localization to nucleus GO:0034504 3 0.037
regulation of protein maturation GO:1903317 10 0.037
cellular response to biotic stimulus GO:0071216 3 0.037
cellular response to organic substance GO:0071310 105 0.037
cell substrate adhesion GO:0031589 4 0.037
regulation of response to stimulus GO:0048583 269 0.037
positive regulation of cell death GO:0010942 29 0.036
response to bacterium GO:0009617 58 0.036
b cell activation GO:0042113 2 0.036
positive regulation of cellular biosynthetic process GO:0031328 68 0.036
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.036
larval development GO:0002164 2 0.035
regulation of primary metabolic process GO:0080090 311 0.035
guanosine containing compound catabolic process GO:1901069 2 0.035
myeloid cell differentiation GO:0030099 86 0.035
regulation of gene expression GO:0010468 265 0.035
cell cycle g1 s phase transition GO:0044843 1 0.035
positive regulation of catabolic process GO:0009896 4 0.035
response to endogenous stimulus GO:0009719 83 0.035
guanosine containing compound metabolic process GO:1901068 4 0.035
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.034
regionalization GO:0003002 274 0.034
regulation of multicellular organismal development GO:2000026 223 0.034
regulation of cellular protein catabolic process GO:1903362 1 0.034
release of sequestered calcium ion into cytosol GO:0051209 3 0.034
regulation of protein catabolic process GO:0042176 1 0.033
death GO:0016265 121 0.033
cellular response to stress GO:0033554 62 0.033
pectoral fin development GO:0033339 50 0.033
positive regulation of striated muscle cell differentiation GO:0051155 1 0.033
cellular response to unfolded protein GO:0034620 2 0.033
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 7 0.033
cellular extravasation GO:0045123 1 0.033
developmental pigmentation GO:0048066 48 0.033
positive regulation of jnk cascade GO:0046330 3 0.033
regulation of nucleotide catabolic process GO:0030811 2 0.033
organic acid metabolic process GO:0006082 31 0.033
vasculature development GO:0001944 278 0.033
eye morphogenesis GO:0048592 144 0.032
positive regulation of macromolecule metabolic process GO:0010604 93 0.032
positive regulation of cell cycle GO:0045787 3 0.032
organic cyclic compound biosynthetic process GO:1901362 223 0.032
multicellular organismal homeostasis GO:0048871 29 0.032
cellular biosynthetic process GO:0044249 286 0.032
lipid metabolic process GO:0006629 52 0.032
positive regulation of muscle cell differentiation GO:0051149 1 0.032
negative regulation of cellular metabolic process GO:0031324 77 0.031
ovulation cycle process GO:0022602 2 0.031
regulation of binding GO:0051098 3 0.031
regulation of protein transport GO:0051223 3 0.031
regulation of cytokine production GO:0001817 3 0.031
response to wounding GO:0009611 116 0.031
regulation of transcription dna templated GO:0006355 213 0.031
cellular macromolecule metabolic process GO:0044260 391 0.031
exocrine pancreas development GO:0031017 28 0.031
regulation of apoptotic signaling pathway GO:2001233 12 0.031
response to decreased oxygen levels GO:0036293 25 0.031
multicellular organismal metabolic process GO:0044236 2 0.030
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.030
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.030
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.030
cell projection morphogenesis GO:0048858 244 0.030
negative regulation of programmed cell death GO:0043069 58 0.030
regulation of cell differentiation GO:0045595 142 0.030
regulation of neurogenesis GO:0050767 87 0.030
positive regulation of nucleic acid templated transcription GO:1903508 57 0.030
negative regulation of macromolecule metabolic process GO:0010605 76 0.029
astrocyte differentiation GO:0048708 1 0.029
response to growth factor GO:0070848 39 0.029
positive regulation of signaling GO:0023056 56 0.029
alpha amino acid metabolic process GO:1901605 3 0.029
circulatory system process GO:0003013 87 0.028
regulation of cell death GO:0010941 103 0.028
regulation of organ growth GO:0046620 3 0.028
negative regulation of apoptotic signaling pathway GO:2001234 10 0.028
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.028
regulation of production of molecular mediator of immune response GO:0002700 1 0.028
positive regulation of jun kinase activity GO:0043507 2 0.028
regulation of protein ubiquitination GO:0031396 3 0.028
microtubule polymerization GO:0046785 2 0.028
positive regulation of cell adhesion GO:0045785 1 0.028
endocrine process GO:0050886 2 0.028
regulation of cellular component organization GO:0051128 86 0.027
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.027
regulation of programmed cell death GO:0043067 101 0.027
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.027
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.027
regulation of localization GO:0032879 104 0.027
negative regulation of protein maturation GO:1903318 10 0.027
cellular response to chemical stimulus GO:0070887 157 0.027
lymphocyte homeostasis GO:0002260 1 0.027
regulation of blood pressure GO:0008217 1 0.027
aromatic compound biosynthetic process GO:0019438 217 0.027
cellular amide metabolic process GO:0043603 4 0.027
negative regulation of nervous system development GO:0051961 22 0.026
rna biosynthetic process GO:0032774 181 0.026
determination of bilateral symmetry GO:0009855 204 0.026
eye photoreceptor cell differentiation GO:0001754 45 0.026
proteasomal protein catabolic process GO:0010498 2 0.026
single organism membrane fusion GO:0044801 2 0.026
negative regulation of kinase activity GO:0033673 4 0.026
regulation of cell motility GO:2000145 46 0.026
response to corticosteroid GO:0031960 1 0.026
negative regulation of protein phosphorylation GO:0001933 4 0.026
response to lipid GO:0033993 60 0.026
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.026
macromolecule modification GO:0043412 111 0.026
cellular hormone metabolic process GO:0034754 19 0.025
vasculogenesis GO:0001570 41 0.025
regulation of nitrogen compound metabolic process GO:0051171 251 0.025
negative regulation of protein complex assembly GO:0031333 1 0.025
apoptotic process GO:0006915 116 0.025
apoptotic process involved in morphogenesis GO:0060561 2 0.025
carboxylic acid metabolic process GO:0019752 22 0.025
positive regulation of cytokine production GO:0001819 2 0.025
mitochondrial transport GO:0006839 2 0.025
fin development GO:0033333 77 0.025
negative regulation of cytokine production GO:0001818 1 0.025
gtp catabolic process GO:0006184 2 0.025
peptidyl serine modification GO:0018209 2 0.025
response to molecule of bacterial origin GO:0002237 14 0.025
peptidyl serine phosphorylation GO:0018105 1 0.025
regulation of heart growth GO:0060420 2 0.024
amine metabolic process GO:0009308 2 0.024
leukocyte homeostasis GO:0001776 2 0.024
regulation of wound healing GO:0061041 2 0.024
negative regulation of protein kinase activity GO:0006469 4 0.024
response to oxygen levels GO:0070482 25 0.024
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 8 0.024
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.024
fat soluble vitamin metabolic process GO:0006775 4 0.024
mononuclear cell proliferation GO:0032943 1 0.024
photoreceptor cell differentiation GO:0046530 55 0.024
phagocytosis GO:0006909 3 0.024
cellular response to molecule of bacterial origin GO:0071219 3 0.023
transcription dna templated GO:0006351 181 0.023
hindbrain development GO:0030902 91 0.023
negative regulation of biosynthetic process GO:0009890 55 0.023
lymphocyte proliferation GO:0046651 1 0.023
heart looping GO:0001947 94 0.023
cell death GO:0008219 121 0.023
response to organic substance GO:0010033 153 0.023
fatty acid biosynthetic process GO:0006633 4 0.023
proteolysis GO:0006508 38 0.023
negative regulation of sequestering of calcium ion GO:0051283 4 0.023
cellular modified amino acid metabolic process GO:0006575 3 0.023
innervation GO:0060384 3 0.023
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.023
cellular response to radiation GO:0071478 4 0.023
positive regulation of gtpase activity GO:0043547 1 0.022
mesenchyme development GO:0060485 127 0.022
regulation of locomotion GO:0040012 55 0.022
collagen metabolic process GO:0032963 2 0.022
negative regulation of cell death GO:0060548 60 0.022
odontogenesis of dentin containing tooth GO:0042475 1 0.022
signal transduction in absence of ligand GO:0038034 1 0.022
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.022
negative regulation of metabolic process GO:0009892 86 0.022
regulation of cellular component movement GO:0051270 55 0.022
cell motility GO:0048870 244 0.022
activation of immune response GO:0002253 9 0.022
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.022
cellular macromolecule biosynthetic process GO:0034645 224 0.022
cell projection assembly GO:0030031 64 0.022
positive regulation of cell proliferation GO:0008284 15 0.022
cytokine metabolic process GO:0042107 1 0.021
neuroblast proliferation GO:0007405 2 0.021
positive regulation of response to stimulus GO:0048584 80 0.021
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.021
t cell differentiation in thymus GO:0033077 6 0.021
single organism localization GO:1902578 225 0.021
cell proliferation GO:0008283 80 0.021
regulation of inflammatory response GO:0050727 2 0.021
cell migration GO:0016477 237 0.021
cell cycle GO:0007049 93 0.021
negative regulation of developmental process GO:0051093 65 0.021
negative regulation of secretion GO:0051048 2 0.021
protein processing GO:0016485 12 0.021
response to estrogen GO:0043627 27 0.021
regulation of purine nucleotide catabolic process GO:0033121 2 0.021
regulation of cell development GO:0060284 100 0.021
determination of left right symmetry GO:0007368 179 0.021
osteoclast differentiation GO:0030316 1 0.021
positive regulation of cytoskeleton organization GO:0051495 3 0.020
protein modification process GO:0036211 100 0.020
t cell differentiation GO:0030217 6 0.020
positive regulation of nucleoside metabolic process GO:0045979 1 0.020
axon development GO:0061564 166 0.020
stem cell differentiation GO:0048863 117 0.020
mitotic dna damage checkpoint GO:0044773 4 0.020
response to hormone GO:0009725 48 0.020
modification dependent macromolecule catabolic process GO:0043632 3 0.020
positive regulation of epithelial cell proliferation GO:0050679 1 0.020
negative regulation of epithelial cell proliferation GO:0050680 1 0.020
mesenchymal cell differentiation GO:0048762 87 0.020
positive regulation of apoptotic process GO:0043065 29 0.020
response to nicotine GO:0035094 2 0.020
s adenosylmethionine metabolic process GO:0046500 1 0.020
regulation of cell substrate adhesion GO:0010810 1 0.020
regulation of gtpase activity GO:0043087 2 0.020
positive regulation of cell communication GO:0010647 56 0.019
negative regulation of map kinase activity GO:0043407 2 0.019
activation of mapk activity GO:0000187 3 0.019
cognition GO:0050890 1 0.019
positive regulation of cell activation GO:0050867 1 0.019
regulation of cell activation GO:0050865 1 0.019
liver development GO:0001889 96 0.019
localization of cell GO:0051674 244 0.019
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.019
cell type specific apoptotic process GO:0097285 22 0.019
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.019
regulation of nervous system development GO:0051960 90 0.019
digestive tract morphogenesis GO:0048546 231 0.019
hepaticobiliary system development GO:0061008 98 0.019
protein homooligomerization GO:0051260 3 0.019
negative regulation of gene expression GO:0010629 65 0.019
heart process GO:0003015 71 0.019
negative regulation of locomotion GO:0040013 18 0.019
cellular component movement GO:0006928 335 0.019
negative regulation of feeding behavior GO:2000252 2 0.019
positive regulation of rna biosynthetic process GO:1902680 57 0.019
regulation of leukocyte differentiation GO:1902105 5 0.019
oxoacid metabolic process GO:0043436 31 0.019
pigmentation GO:0043473 85 0.019
cellular component assembly involved in morphogenesis GO:0010927 107 0.019
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.018
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.018
protein import GO:0017038 3 0.018
regulation of response to biotic stimulus GO:0002831 2 0.018
mitotic cell cycle GO:0000278 64 0.018
stem cell proliferation GO:0072089 4 0.018
regulation of anatomical structure morphogenesis GO:0022603 130 0.018
embryonic appendage morphogenesis GO:0035113 30 0.018
head development GO:0060322 303 0.018
macromolecular complex assembly GO:0065003 35 0.018
cell part morphogenesis GO:0032990 246 0.018
response to glucocorticoid GO:0051384 1 0.018
antimicrobial humoral response GO:0019730 2 0.018
wnt signaling pathway GO:0016055 80 0.018
positive regulation of protein polymerization GO:0032273 2 0.018
pharyngeal system development GO:0060037 18 0.017
regulation of gtp catabolic process GO:0033124 2 0.017
growth GO:0040007 174 0.017
cardiac atrium morphogenesis GO:0003209 2 0.017
er nucleus signaling pathway GO:0006984 2 0.017
negative regulation of dna replication GO:0008156 2 0.017
immune system process GO:0002376 241 0.017
macromolecule biosynthetic process GO:0009059 227 0.017
peripheral nervous system development GO:0007422 55 0.017
response to nutrient levels GO:0031667 10 0.017
pigment granule transport GO:0051904 19 0.017
ovulation cycle GO:0042698 2 0.017
sensory perception of chemical stimulus GO:0007606 3 0.017
regulation of developmental growth GO:0048638 38 0.017
olfactory lobe development GO:0021988 4 0.017
ear development GO:0043583 127 0.017
regulation of bone remodeling GO:0046850 2 0.016
response to antibiotic GO:0046677 1 0.016
sensory organ morphogenesis GO:0090596 200 0.016
cytokinetic process GO:0032506 2 0.016
negative regulation of chromosome organization GO:2001251 1 0.016
muscle cell migration GO:0014812 4 0.016
positive regulation of gtp catabolic process GO:0033126 1 0.016
negative regulation of cellular component organization GO:0051129 16 0.016
development of primary female sexual characteristics GO:0046545 4 0.016
regulation of organelle assembly GO:1902115 4 0.016
negative regulation of mrna metabolic process GO:1903312 3 0.016
appendage morphogenesis GO:0035107 56 0.016
cell fate specification GO:0001708 68 0.016
embryonic organ development GO:0048568 381 0.016
regulation of cytoplasmic transport GO:1903649 4 0.016
single organism cellular localization GO:1902580 46 0.016
regulation of carbohydrate metabolic process GO:0006109 4 0.016
regulation of cellular biosynthetic process GO:0031326 245 0.016
cellular response to organic cyclic compound GO:0071407 38 0.015
membrane fusion GO:0061025 2 0.015
tissue homeostasis GO:0001894 25 0.015
single organism transport GO:0044765 206 0.015
regulation of endothelial cell proliferation GO:0001936 1 0.015
heart contraction GO:0060047 71 0.015
protein targeting to nucleus GO:0044744 3 0.015
homeostasis of number of cells GO:0048872 62 0.015
neuron development GO:0048666 262 0.015
embryo development ending in birth or egg hatching GO:0009792 271 0.015
response to uv GO:0009411 3 0.015
formation of primary germ layer GO:0001704 62 0.015
positive regulation of muscle organ development GO:0048636 1 0.015
nuclear import GO:0051170 3 0.015
negative regulation of endopeptidase activity GO:0010951 10 0.015
carbohydrate homeostasis GO:0033500 1 0.015
response to unfolded protein GO:0006986 2 0.015
germ line stem cell maintenance GO:0030718 2 0.015
embryonic organ morphogenesis GO:0048562 274 0.015
negative regulation of cellular biosynthetic process GO:0031327 55 0.015
regulation of response to nutrient levels GO:0032107 1 0.015
cell cycle arrest GO:0007050 1 0.015
protein complex assembly GO:0006461 30 0.015
specification of organ identity GO:0010092 2 0.015
regulation of cellular extravasation GO:0002691 1 0.015
regulation of cell projection assembly GO:0060491 4 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.015
somatic stem cell maintenance GO:0035019 1 0.015
protein maturation GO:0051604 12 0.014
regulation of systemic arterial blood pressure GO:0003073 1 0.014
single organism organelle organization GO:1902589 199 0.014
regulation of cell shape GO:0008360 1 0.014
cellular protein catabolic process GO:0044257 4 0.014
negative regulation of dna metabolic process GO:0051053 4 0.014
cellular component disassembly GO:0022411 1 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.014
stem cell division GO:0017145 1 0.014
regulation of endopeptidase activity GO:0052548 23 0.014
negative regulation of cell differentiation GO:0045596 46 0.014
glial cell differentiation GO:0010001 42 0.014
lymphocyte differentiation GO:0030098 9 0.014
transport GO:0006810 220 0.014
anatomical structure homeostasis GO:0060249 36 0.014
organelle organization GO:0006996 227 0.014

cdkn1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
large intestine cancer DOID:5672 0 0.147
gastrointestinal system cancer DOID:3119 0 0.147
intestinal cancer DOID:10155 0 0.147
cancer DOID:162 0 0.147
disease of cellular proliferation DOID:14566 0 0.147
organ system cancer DOID:0050686 0 0.147
disease of anatomical entity DOID:7 0 0.073
colon carcinoma DOID:1520 0 0.060
colon cancer DOID:219 0 0.060
colorectal cancer DOID:9256 0 0.060
disease of metabolism DOID:0014667 0 0.024