Danio rerio

115 known processes

tbx20

T-box 20

(Aliases: cb826,hrt,ZF-TBX20)

tbx20 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of multicellular organismal development GO:2000026 223 0.991
Zebrafish Mouse
muscle tissue development GO:0060537 110 0.987
Zebrafish Mouse
gastrulation GO:0007369 208 0.986
Zebrafish
heart development GO:0007507 313 0.983
heterocycle biosynthetic process GO:0018130 215 0.983
cardiac conduction system development GO:0003161 1 0.977
segmentation GO:0035282 97 0.971
Zebrafish
cardiac chamber formation GO:0003207 4 0.970
Mouse
embryonic heart tube development GO:0035050 133 0.968
digestive system development GO:0055123 289 0.964
cardiac muscle tissue development GO:0048738 48 0.964
Zebrafish Mouse
digestive tract morphogenesis GO:0048546 231 0.960
determination of left right symmetry GO:0007368 179 0.958
cellular component movement GO:0006928 335 0.955
Zebrafish Mouse
atrioventricular valve formation GO:0003190 3 0.955
Zebrafish
striated muscle tissue development GO:0014706 110 0.951
Zebrafish Mouse
heart contraction GO:0060047 71 0.950
Zebrafish
striated muscle cell development GO:0055002 108 0.950
tube morphogenesis GO:0035239 349 0.949
regulation of anatomical structure morphogenesis GO:0022603 130 0.942
Zebrafish
digestive tract development GO:0048565 265 0.941
muscle cell differentiation GO:0042692 139 0.934
Zebrafish
regulation of nitrogen compound metabolic process GO:0051171 251 0.928
central nervous system development GO:0007417 387 0.924
Zebrafish Mouse
determination of bilateral symmetry GO:0009855 204 0.923
specification of symmetry GO:0009799 204 0.921
heart looping GO:0001947 94 0.919
heart valve morphogenesis GO:0003179 8 0.912
Zebrafish Mouse
diencephalon development GO:0021536 58 0.906
Zebrafish
ameboidal type cell migration GO:0001667 143 0.902
Zebrafish
cellular nitrogen compound biosynthetic process GO:0044271 218 0.892
vasculature development GO:0001944 278 0.888
convergent extension GO:0060026 118 0.888
Zebrafish
morphogenesis of an epithelium GO:0002009 333 0.884
heart valve formation GO:0003188 4 0.883
Zebrafish Mouse
regulation of biosynthetic process GO:0009889 250 0.883
response to chemical GO:0042221 320 0.883
embryonic organ development GO:0048568 381 0.881
heart field specification GO:0003128 1 0.879
locomotion GO:0040011 313 0.874
Zebrafish Mouse Worm
positive regulation of gene expression GO:0010628 71 0.868
Zebrafish Mouse
cardiocyte differentiation GO:0035051 44 0.865
Zebrafish
regulation of bmp signaling pathway involved in heart jogging GO:2000223 12 0.863
Zebrafish
pericardium development GO:0060039 1 0.862
Zebrafish Mouse
cell migration involved in heart development GO:0060973 22 0.860
positive regulation of biological process GO:0048518 253 0.860
Zebrafish Mouse
ventral spinal cord development GO:0021517 35 0.855
Zebrafish Mouse
cardiac cell fate commitment GO:0060911 1 0.845
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.844
embryonic heart tube morphogenesis GO:0003143 108 0.843
generation of neurons GO:0048699 385 0.796
Zebrafish Mouse
muscle structure development GO:0061061 196 0.780
Zebrafish Mouse
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.772
regulation of blood circulation GO:1903522 32 0.765
Zebrafish
nucleobase containing compound biosynthetic process GO:0034654 205 0.762
positive regulation of biosynthetic process GO:0009891 68 0.761
Zebrafish Mouse
mesoderm formation GO:0001707 43 0.760
Zebrafish
bmp signaling pathway involved in determination of left right symmetry GO:0003154 14 0.758
Zebrafish
regulation of developmental process GO:0050793 247 0.756
Zebrafish Mouse
regulation of metabolic process GO:0019222 359 0.754
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.751
cellular biosynthetic process GO:0044249 286 0.750
regulation of heart morphogenesis GO:2000826 17 0.749
Zebrafish
regulation of heart contraction GO:0008016 32 0.748
Zebrafish
cell migration involved in gastrulation GO:0042074 79 0.748
Zebrafish
regulation of embryonic development GO:0045995 47 0.739
Zebrafish
convergent extension involved in gastrulation GO:0060027 71 0.733
spinal cord development GO:0021510 46 0.731
Zebrafish Mouse
cell death GO:0008219 121 0.730
cell motility GO:0048870 244 0.727
Zebrafish Mouse
blood vessel development GO:0001568 246 0.725
apoptotic process GO:0006915 116 0.719
transcription from rna polymerase ii promoter GO:0006366 80 0.718
Zebrafish Mouse
atrioventricular valve development GO:0003171 11 0.705
Zebrafish Mouse
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.699
Zebrafish Mouse
negative regulation of biological process GO:0048519 304 0.698
embryonic axis specification GO:0000578 12 0.688
regulation of cellular biosynthetic process GO:0031326 245 0.679
cell migration to the midline involved in heart development GO:0003318 12 0.664
blood vessel morphogenesis GO:0048514 216 0.661
atrioventricular valve morphogenesis GO:0003181 6 0.658
Zebrafish
positive regulation of nucleic acid templated transcription GO:1903508 57 0.654
Zebrafish Mouse
cell migration GO:0016477 237 0.646
Zebrafish Mouse
regulation of macromolecule biosynthetic process GO:0010556 225 0.645
gene expression GO:0010467 252 0.644
regulation of signaling GO:0023051 235 0.640
Zebrafish Mouse
regionalization GO:0003002 274 0.635
Zebrafish Mouse
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.633
mesodermal to mesenchymal transition involved in gastrulation GO:0060809 1 0.631
Zebrafish
cell projection organization GO:0030030 284 0.621
invagination involved in gastrulation with mouth forming second GO:0055109 1 0.621
Zebrafish
neuron differentiation GO:0030182 353 0.619
Zebrafish Mouse
response to external stimulus GO:0009605 264 0.609
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.600
Zebrafish Mouse
embryonic pattern specification GO:0009880 44 0.598
regulation of apoptotic process GO:0042981 98 0.593
retinal rod cell development GO:0046548 4 0.590
Zebrafish
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.588
Zebrafish Mouse
rna metabolic process GO:0016070 219 0.586
cell differentiation in spinal cord GO:0021515 40 0.584
Zebrafish Mouse
negative regulation of heart contraction GO:0045822 2 0.579
heart morphogenesis GO:0003007 156 0.576
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.575
Zebrafish
bmp signaling pathway involved in heart development GO:0061312 15 0.573
Zebrafish
transcription dna templated GO:0006351 181 0.568
organic cyclic compound biosynthetic process GO:1901362 223 0.561
determination of heart left right asymmetry GO:0061371 117 0.561
bmp signaling pathway involved in heart jogging GO:0003303 14 0.560
Zebrafish
heart formation GO:0060914 13 0.554
Zebrafish
positive regulation of rna metabolic process GO:0051254 59 0.550
Zebrafish Mouse
regulation of nucleic acid templated transcription GO:1903506 213 0.546
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.536
Zebrafish Mouse
heart jogging GO:0003146 40 0.534
Zebrafish
regulation of transcription dna templated GO:0006355 213 0.532
cell morphogenesis GO:0000902 289 0.531
Zebrafish
cardiac atrium morphogenesis GO:0003209 2 0.530
cardiac cell development GO:0055006 21 0.526
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 17 0.522
Zebrafish
cardiac muscle cell differentiation GO:0055007 30 0.517
Zebrafish
regulation of gene expression GO:0010468 265 0.517
endodermal cell fate commitment GO:0001711 18 0.513
Zebrafish
heterocycle metabolic process GO:0046483 290 0.510
semicircular canal development GO:0060872 24 0.508
Zebrafish
regulation of cell death GO:0010941 103 0.506
cellular component morphogenesis GO:0032989 336 0.504
Zebrafish
regulation of macromolecule metabolic process GO:0060255 317 0.498
formation of primary germ layer GO:0001704 62 0.498
Zebrafish
positive regulation of muscle organ development GO:0048636 1 0.494
Mouse
regulation of programmed cell death GO:0043067 101 0.492
positive regulation of cellular process GO:0048522 201 0.490
Zebrafish Mouse
endocrine system development GO:0035270 65 0.486
tissue remodeling GO:0048771 4 0.485
Zebrafish
rna biosynthetic process GO:0032774 181 0.473
regulation of primary metabolic process GO:0080090 311 0.471
cellular nitrogen compound metabolic process GO:0034641 290 0.471
positive regulation of cellular biosynthetic process GO:0031328 68 0.471
Zebrafish Mouse
neuron projection development GO:0031175 180 0.470
positive regulation of rna biosynthetic process GO:1902680 57 0.467
Zebrafish Mouse
regulation of cellular metabolic process GO:0031323 320 0.465
muscle cell fate determination GO:0007521 1 0.458
stem cell differentiation GO:0048863 117 0.458
Zebrafish
anterior posterior pattern specification GO:0009952 152 0.453
Zebrafish
cellular aromatic compound metabolic process GO:0006725 295 0.451
regulation of cell differentiation GO:0045595 142 0.449
central nervous system neuron differentiation GO:0021953 74 0.446
Zebrafish Mouse
ear development GO:0043583 127 0.439
Zebrafish
neuron development GO:0048666 262 0.427
Zebrafish
regulation of multicellular organismal process GO:0051239 277 0.427
Zebrafish Mouse
cellular macromolecule metabolic process GO:0044260 391 0.426
cardiac muscle cell development GO:0055013 20 0.425
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.425
Mouse
cellular macromolecule biosynthetic process GO:0034645 224 0.419
nitrogen compound metabolic process GO:0006807 319 0.417
cell surface receptor signaling pathway GO:0007166 325 0.415
Zebrafish Mouse
regulation of rna biosynthetic process GO:2001141 213 0.414
regulation of cell development GO:0060284 100 0.412
programmed cell death GO:0012501 119 0.411
axonogenesis GO:0007409 152 0.403
stem cell development GO:0048864 82 0.400
Zebrafish
signal transduction GO:0007165 455 0.394
Zebrafish Mouse
regulation of muscle organ development GO:0048634 9 0.387
Mouse
muscle cell development GO:0055001 115 0.384
chemotaxis GO:0006935 104 0.381
regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901213 15 0.380
Zebrafish
regulation of cell proliferation involved in heart morphogenesis GO:2000136 2 0.377
Zebrafish
immune system process GO:0002376 241 0.372
biosynthetic process GO:0009058 294 0.353
mesenchyme development GO:0060485 127 0.352
Zebrafish Mouse
photoreceptor cell fate specification GO:0043704 1 0.351
Zebrafish
pericardium morphogenesis GO:0003344 1 0.348
Zebrafish Mouse
negative regulation of cell communication GO:0010648 96 0.347
Mouse
cellular response to chemical stimulus GO:0070887 157 0.341
regulation of skeletal muscle tissue development GO:0048641 4 0.341
cell proliferation involved in heart morphogenesis GO:0061323 2 0.336
Zebrafish
striated muscle cell differentiation GO:0051146 129 0.335
Zebrafish
endodermal cell differentiation GO:0035987 19 0.335
Zebrafish
negative regulation of mesodermal cell fate specification GO:0042662 3 0.334
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.333
Zebrafish Mouse
negative regulation of multicellular organismal process GO:0051241 69 0.328
response to endogenous stimulus GO:0009719 83 0.328
heart process GO:0003015 71 0.324
Zebrafish
somitogenesis GO:0001756 87 0.322
Zebrafish
positive regulation of muscle tissue development GO:1901863 1 0.321
Mouse
nucleobase containing compound metabolic process GO:0006139 274 0.318
larval development GO:0002164 2 0.316
regulation of cellular component organization GO:0051128 86 0.313
Mouse
cardioblast migration to the midline involved in heart field formation GO:0060975 7 0.310
ventricular cardiac muscle tissue development GO:0003229 3 0.310
negative regulation of cellular process GO:0048523 283 0.304
positive regulation of cellular metabolic process GO:0031325 94 0.302
Zebrafish Mouse
regulation of cell communication GO:0010646 232 0.293
Zebrafish Mouse
hematopoietic or lymphoid organ development GO:0048534 191 0.290
positive regulation of striated muscle tissue development GO:0045844 1 0.290
Mouse
pronephros development GO:0048793 69 0.283
Zebrafish
circadian sleep wake cycle GO:0042745 2 0.281
gland development GO:0048732 143 0.280
regulation of heart growth GO:0060420 2 0.277
Mouse
actomyosin structure organization GO:0031032 53 0.275
cell morphogenesis involved in differentiation GO:0000904 195 0.273
Zebrafish
angiogenesis GO:0001525 158 0.273
Zebrafish Mouse
organic substance biosynthetic process GO:1901576 289 0.272
enzyme linked receptor protein signaling pathway GO:0007167 106 0.271
Zebrafish Mouse
death GO:0016265 121 0.265
cardiac ventricle formation GO:0003211 1 0.265
regulation of stem cell differentiation GO:2000736 4 0.257
intermediate mesoderm development GO:0048389 2 0.256
Zebrafish
photoreceptor cell fate commitment GO:0046552 1 0.255
Zebrafish
cardiac chamber development GO:0003205 19 0.253
Zebrafish Mouse
negative regulation of blood circulation GO:1903523 2 0.246
endocardium morphogenesis GO:0003160 4 0.246
localization of cell GO:0051674 244 0.245
Zebrafish Mouse
circadian sleep wake cycle process GO:0022410 2 0.243
intracellular signal transduction GO:0035556 85 0.242
axon guidance GO:0007411 86 0.236
cardioblast migration GO:0003260 7 0.236
regulation of epidermis development GO:0045682 2 0.234
atrial ventricular junction remodeling GO:0003294 2 0.233
Zebrafish
negative regulation of developmental process GO:0051093 65 0.230
regulation of cardiac muscle tissue development GO:0055024 1 0.229
Mouse
regulation of circadian rhythm GO:0042752 4 0.226
nucleic acid templated transcription GO:0097659 181 0.224
artery development GO:0060840 22 0.221
epithelial tube morphogenesis GO:0060562 148 0.215
head development GO:0060322 303 0.214
Zebrafish
actin filament based process GO:0030029 64 0.214
axis specification GO:0009798 43 0.210
rhombomere boundary formation GO:0021654 10 0.206
response to abiotic stimulus GO:0009628 122 0.205
regulation of organ morphogenesis GO:2000027 35 0.199
Zebrafish
circadian sleep wake cycle sleep GO:0050802 1 0.198
regulation of endodermal cell differentiation GO:1903224 15 0.195
urogenital system development GO:0001655 97 0.194
spinal cord motor neuron differentiation GO:0021522 26 0.193
Zebrafish Mouse
axon development GO:0061564 166 0.191
behavior GO:0007610 74 0.188
ventricular cardiac muscle cell development GO:0055015 5 0.185
embryo development ending in birth or egg hatching GO:0009792 271 0.184
Zebrafish Worm
morphogenesis of a branching structure GO:0001763 21 0.182
Mouse
cellular component assembly GO:0022607 170 0.180
Mouse
specification of organ position GO:0010159 3 0.180
Zebrafish
macromolecule biosynthetic process GO:0009059 227 0.179
cell projection morphogenesis GO:0048858 244 0.176
myotube differentiation GO:0014902 45 0.176
negative regulation of cell fate commitment GO:0010454 13 0.172
regulation of rna metabolic process GO:0051252 224 0.171
cell surface receptor signaling pathway involved in heart development GO:0061311 20 0.171
Zebrafish
aging GO:0007568 2 0.169
circulatory system process GO:0003013 87 0.168
Zebrafish Mouse
heart valve development GO:0003170 14 0.168
Zebrafish Mouse
positive regulation of transcription dna templated GO:0045893 57 0.167
Zebrafish Mouse
cellular response to organic substance GO:0071310 105 0.166
regulation of neurotransmitter transport GO:0051588 1 0.166
cardiogenic plate morphogenesis GO:0003142 1 0.165
taxis GO:0042330 109 0.164
motor neuron axon guidance GO:0008045 23 0.161
neuron projection morphogenesis GO:0048812 161 0.159
cell part morphogenesis GO:0032990 246 0.158
regulation of striated muscle tissue development GO:0016202 6 0.157
Mouse
anterior posterior axis specification GO:0009948 20 0.151
cell fate specification GO:0001708 68 0.150
Zebrafish Worm
regulation of organelle assembly GO:1902115 4 0.150
gastrulation with mouth forming second GO:0001702 44 0.148
Zebrafish
positive regulation of multicellular organismal process GO:0051240 52 0.148
Mouse
eye photoreceptor cell development GO:0042462 30 0.147
Zebrafish
mesodermal cell differentiation GO:0048333 21 0.147
astrocyte differentiation GO:0048708 1 0.145
nephric duct development GO:0072176 13 0.144
Zebrafish
vasculogenesis GO:0001570 41 0.144
regulation of cardiac chamber formation GO:1901210 2 0.142
negative regulation of gene expression GO:0010629 65 0.141
mesoderm morphogenesis GO:0048332 51 0.138
Zebrafish
regulation of epithelial to mesenchymal transition GO:0010717 3 0.137
primitive hemopoiesis GO:0060215 27 0.137
regulation of skeletal muscle fiber development GO:0048742 2 0.136
regulation of system process GO:0044057 40 0.136
Zebrafish
developmental process involved in reproduction GO:0003006 27 0.135
Worm
camera type eye photoreceptor cell differentiation GO:0060219 19 0.133
Zebrafish
apoptotic process involved in morphogenesis GO:0060561 2 0.133
bmp signaling pathway GO:0030509 52 0.133
Zebrafish
positive regulation of cell motility GO:2000147 11 0.133
negative regulation of cell death GO:0060548 60 0.132
neural retina development GO:0003407 49 0.132
Zebrafish
nucleic acid metabolic process GO:0090304 244 0.130
somite development GO:0061053 96 0.126
Zebrafish
endodermal cell fate specification GO:0001714 17 0.126
Zebrafish
female sex differentiation GO:0046660 4 0.122
negative regulation of cell differentiation GO:0045596 46 0.121
negative regulation of apoptotic process GO:0043066 55 0.120
positive regulation of transport GO:0051050 2 0.120
embryonic hemopoiesis GO:0035162 53 0.119
hormone mediated signaling pathway GO:0009755 9 0.118
regulation of organ growth GO:0046620 3 0.117
Mouse
notochord cell differentiation GO:0060034 18 0.117
Zebrafish
negative regulation of programmed cell death GO:0043069 58 0.117
brain development GO:0007420 293 0.117
Zebrafish
cardiac chamber morphogenesis GO:0003206 12 0.116
Mouse
multi organism process GO:0051704 134 0.115
organ formation GO:0048645 17 0.115
Zebrafish
aorta development GO:0035904 4 0.115
aorta morphogenesis GO:0035909 3 0.114
regulation of signal transduction GO:0009966 225 0.114
Zebrafish Mouse
response to stress GO:0006950 263 0.111
connective tissue development GO:0061448 99 0.108
Zebrafish
regulation of endodermal cell fate specification GO:0042663 15 0.108
endoderm formation GO:0001706 29 0.107
Zebrafish
negative regulation of muscle organ development GO:0048635 5 0.106
semicircular canal morphogenesis GO:0048752 18 0.106
Zebrafish
embryonic organ morphogenesis GO:0048562 274 0.106
response to organic substance GO:0010033 153 0.106
g protein coupled receptor signaling pathway GO:0007186 74 0.106
renal system vasculature development GO:0061437 2 0.105
response to oxygen levels GO:0070482 25 0.104
regulation of reproductive process GO:2000241 4 0.104
atrial cardiac muscle cell development GO:0055014 4 0.103
regulation of mesodermal cell fate specification GO:0042661 9 0.103
stem cell division GO:0017145 1 0.102
regulation of oocyte development GO:0060281 3 0.102
rhombomere morphogenesis GO:0021593 17 0.101
negative regulation of muscle cell differentiation GO:0051148 1 0.101
response to nitrogen compound GO:1901698 19 0.101
cell fate commitment GO:0045165 99 0.101
Zebrafish Worm
gabaergic neuron differentiation GO:0097154 2 0.099
kidney development GO:0001822 92 0.099
Zebrafish
organic cyclic compound metabolic process GO:1901360 301 0.099
sensory organ morphogenesis GO:0090596 200 0.097
Zebrafish
myofibril assembly GO:0030239 48 0.097
regulation of biological quality GO:0065008 263 0.096
Zebrafish
rhombomere development GO:0021546 19 0.095
inner ear morphogenesis GO:0042472 63 0.095
Zebrafish
response to other organism GO:0051707 97 0.094
regulation of response to stimulus GO:0048583 269 0.094
Zebrafish Mouse
regulation of mesoderm development GO:2000380 11 0.092
regulation of circadian sleep wake cycle GO:0042749 1 0.092
muscle organ development GO:0007517 101 0.090
Zebrafish Mouse
negative regulation of biosynthetic process GO:0009890 55 0.089
actin cytoskeleton organization GO:0030036 63 0.089
developmental growth GO:0048589 166 0.089
Zebrafish Mouse
ventricular cardiac muscle cell differentiation GO:0055012 6 0.088
thyroid gland development GO:0030878 12 0.087
glial cell differentiation GO:0010001 42 0.087
cell migration involved in heart formation GO:0060974 10 0.087
foregut morphogenesis GO:0007440 4 0.086
pharynx development GO:0060465 5 0.084
Zebrafish
blood circulation GO:0008015 87 0.084
Zebrafish Mouse
angioblast cell migration involved in selective angioblast sprouting GO:0035475 4 0.084
hypothalamus cell differentiation GO:0021979 4 0.083
immune system development GO:0002520 191 0.083
muscle fiber development GO:0048747 52 0.082
multicellular organism reproduction GO:0032504 35 0.082
forebrain development GO:0030900 96 0.082
Zebrafish
glomerulus vasculature development GO:0072012 2 0.082
negative regulation of response to stimulus GO:0048585 104 0.081
Mouse
regulation of protein complex assembly GO:0043254 3 0.080
Mouse
adrenal gland development GO:0030325 10 0.080
embryonic digestive tract development GO:0048566 4 0.079
arterial endothelial cell differentiation GO:0060842 2 0.077
primary amino compound biosynthetic process GO:1901162 1 0.077
regulation of cardiac chamber morphogenesis GO:1901219 2 0.076
cardiac ventricle morphogenesis GO:0003208 7 0.076
Mouse
anatomical structure arrangement GO:0048532 2 0.076
septum transversum development GO:0003343 4 0.074
Zebrafish
cardiac ventricle development GO:0003231 9 0.072
Mouse
cellular component assembly involved in morphogenesis GO:0010927 107 0.072
regulation of growth GO:0040008 42 0.071
Mouse
negative regulation of signaling GO:0023057 96 0.071
Mouse
regulation of cell migration GO:0030334 40 0.070
positive regulation of gliogenesis GO:0014015 2 0.070
epithelial cell differentiation GO:0030855 116 0.070
cell cell signaling GO:0007267 52 0.069
negative regulation of intracellular signal transduction GO:1902532 22 0.068
negative regulation of striated muscle tissue development GO:0045843 2 0.068
atrial cardiac muscle cell differentiation GO:0055011 5 0.066
specification of organ identity GO:0010092 2 0.066
positive regulation of endothelial cell differentiation GO:0045603 2 0.065
negative regulation of striated muscle cell differentiation GO:0051154 1 0.065
mesendoderm development GO:0048382 10 0.062
Zebrafish
homeostatic process GO:0042592 142 0.062
Zebrafish
positive regulation of macromolecule metabolic process GO:0010604 93 0.062
Zebrafish Mouse
heart growth GO:0060419 7 0.062
Mouse
endocardium formation GO:0060214 1 0.061
photoreceptor cell differentiation GO:0046530 55 0.061
Zebrafish
extracellular matrix assembly GO:0085029 1 0.060
proepicardium development GO:0003342 4 0.060
Zebrafish
reproductive process GO:0022414 40 0.060
Worm
pancreas development GO:0031016 84 0.059
ear morphogenesis GO:0042471 64 0.059
Zebrafish
neurotransmitter secretion GO:0007269 2 0.058
pronephros morphogenesis GO:0072114 14 0.058
Zebrafish
endocrine pancreas development GO:0031018 27 0.058
skeletal system development GO:0001501 181 0.057
Zebrafish
mechanoreceptor differentiation GO:0042490 37 0.056
appendage development GO:0048736 80 0.056
Zebrafish
divalent inorganic cation homeostasis GO:0072507 22 0.056
skin development GO:0043588 54 0.056
regulation of vasculature development GO:1901342 33 0.056
positive regulation of cell death GO:0010942 29 0.055
nerve development GO:0021675 45 0.055
Zebrafish
mesodermal cell fate specification GO:0007501 12 0.055
negative regulation of metabolic process GO:0009892 86 0.055
regulation of autophagy GO:0010506 3 0.054
nitric oxide biosynthetic process GO:0006809 2 0.053
regulation of glial cell differentiation GO:0045685 4 0.053
regulation of developmental growth GO:0048638 38 0.053
Mouse
hindbrain development GO:0030902 91 0.051
nephron epithelium morphogenesis GO:0072088 1 0.051
negative regulation of protein complex assembly GO:0031333 1 0.051
Mouse
calcium ion homeostasis GO:0055074 19 0.051
response to growth factor GO:0070848 39 0.051
regulation of cell fate commitment GO:0010453 22 0.050
artery morphogenesis GO:0048844 14 0.050
regulation of cell morphogenesis GO:0022604 42 0.049
positive regulation of glial cell differentiation GO:0045687 1 0.049
positive regulation of nervous system development GO:0051962 25 0.049
reactive oxygen species biosynthetic process GO:1903409 1 0.049
nephron tubule morphogenesis GO:0072078 1 0.049
lipid catabolic process GO:0016042 4 0.048
macromolecular complex subunit organization GO:0043933 74 0.048
Mouse
myeloid cell differentiation GO:0030099 86 0.047
Zebrafish
regulation of cell motility GO:2000145 46 0.047
regulation of jak stat cascade GO:0046425 3 0.047
heart rudiment development GO:0003313 8 0.047
neural crest cell migration GO:0001755 42 0.047
Zebrafish
dorsal aorta morphogenesis GO:0035912 3 0.047
oocyte differentiation GO:0009994 14 0.046
neuron projection guidance GO:0097485 86 0.046
limbic system development GO:0021761 16 0.046
response to organic cyclic compound GO:0014070 51 0.045
cellular response to oxygen levels GO:0071453 1 0.045
regulation of cellular component movement GO:0051270 55 0.045
determination of digestive tract left right asymmetry GO:0071907 10 0.045
morphogenesis of an epithelial sheet GO:0002011 49 0.045
Zebrafish Mouse
pancreatic d cell development GO:0003324 1 0.043
sprouting angiogenesis GO:0002040 53 0.043
developmental programmed cell death GO:0010623 4 0.043
hepatocyte differentiation GO:0070365 1 0.043
glomerulus development GO:0032835 27 0.043
smooth muscle contraction GO:0006939 2 0.041
negative regulation of macromolecule metabolic process GO:0010605 76 0.041
negative regulation of gastrulation GO:2000542 11 0.041
cellular response to growth factor stimulus GO:0071363 39 0.041
regulation of neuron differentiation GO:0045664 56 0.040
stem cell maintenance GO:0019827 4 0.040
positive regulation of developmental process GO:0051094 50 0.040
Mouse
reproduction GO:0000003 40 0.040
semicircular canal formation GO:0060876 4 0.040
cloaca development GO:0035844 9 0.039
cardiac atrium development GO:0003230 4 0.039
regulation of cell fate specification GO:0042659 20 0.039
cellular component biogenesis GO:0044085 178 0.039
Mouse
reactive nitrogen species metabolic process GO:2001057 0 0.038
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.038
Zebrafish Mouse
muscle cell fate commitment GO:0042693 9 0.038
endocardium development GO:0003157 9 0.038
peripheral nervous system development GO:0007422 55 0.038
regulation of synapse organization GO:0050807 3 0.038
aromatic amino acid family metabolic process GO:0009072 1 0.038
cellular localization GO:0051641 97 0.038
multi organism reproductive process GO:0044703 36 0.037
retinal cone cell differentiation GO:0042670 12 0.037
Zebrafish
epidermis development GO:0008544 48 0.037
cell substrate adhesion GO:0031589 4 0.037
regulation of sarcomere organization GO:0060297 2 0.037
growth GO:0040007 174 0.037
Zebrafish Mouse
hemopoiesis GO:0030097 183 0.037
cellular response to molecule of bacterial origin GO:0071219 3 0.036
negative regulation of cell fate specification GO:0009996 11 0.036
floor plate formation GO:0021508 12 0.036
positive regulation of muscle cell differentiation GO:0051149 1 0.036
regulation of oligodendrocyte differentiation GO:0048713 1 0.035
hepaticobiliary system development GO:0061008 98 0.035
negative regulation of signal transduction GO:0009968 94 0.035
Mouse
intrahepatic bile duct development GO:0035622 11 0.035
hematopoietic stem cell differentiation GO:0060218 20 0.035
Zebrafish
positive regulation of locomotion GO:0040017 14 0.035
cellular response to toxic substance GO:0097237 1 0.035
glial cell migration GO:0008347 3 0.035
myeloid cell development GO:0061515 32 0.035
outflow tract morphogenesis GO:0003151 1 0.035
Mouse
germ line stem cell division GO:0042078 1 0.034
germ cell development GO:0007281 22 0.034
rhythmic behavior GO:0007622 5 0.034
epidermal cell differentiation GO:0009913 36 0.034
determination of dorsal ventral asymmetry GO:0048262 34 0.034
Zebrafish
axonal defasciculation GO:0007414 2 0.034
negative regulation of cellular metabolic process GO:0031324 77 0.034
regulation of angiogenesis GO:0045765 26 0.033
gliogenesis GO:0042063 45 0.033
regulation of synaptic plasticity GO:0048167 1 0.033
neuron projection extension GO:1990138 45 0.033
forebrain cell migration GO:0021885 1 0.033
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.033
blastoderm segmentation GO:0007350 6 0.033
pancreatic a cell development GO:0003322 2 0.033

tbx20 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.671
cardiovascular system disease DOID:1287 0 0.124
musculoskeletal system disease DOID:17 0 0.103
disease of metabolism DOID:0014667 0 0.064
physical disorder DOID:0080015 0 0.046
muscular disease DOID:0080000 0 0.034