Danio rerio

43 known processes

tardbp

TAR DNA binding protein

(Aliases: wu:fc52g10,wu:fb77f02,fc52g10,fb77f02)

tardbp biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nucleic acid metabolic process GO:0090304 244 0.828
Human Mouse
regulation of gene expression GO:0010468 265 0.819
Human Mouse
gene expression GO:0010467 252 0.786
Human Mouse
regulation of developmental process GO:0050793 247 0.769
Fly
cellular aromatic compound metabolic process GO:0006725 295 0.757
Human Mouse
nucleobase containing compound metabolic process GO:0006139 274 0.704
Human Mouse
negative regulation of cellular process GO:0048523 283 0.632
Human Fly
rna metabolic process GO:0016070 219 0.607
Human Mouse
larval development GO:0002164 2 0.571
biosynthetic process GO:0009058 294 0.557
Human Mouse
regulation of biosynthetic process GO:0009889 250 0.555
Human Mouse
central nervous system development GO:0007417 387 0.549
Fly
cellular macromolecule metabolic process GO:0044260 391 0.531
Human Mouse
regulation of macromolecule metabolic process GO:0060255 317 0.479
Human Mouse
aromatic compound biosynthetic process GO:0019438 217 0.470
Human Mouse
organic cyclic compound metabolic process GO:1901360 301 0.468
Human Mouse
dorsal ventral pattern formation GO:0009953 125 0.466
regulation of metabolic process GO:0019222 359 0.460
Human Mouse
cellular component assembly GO:0022607 170 0.458
Fly
cellular component movement GO:0006928 335 0.455
protein metabolic process GO:0019538 183 0.442
nucleobase containing compound biosynthetic process GO:0034654 205 0.439
Human Mouse
cellular macromolecule biosynthetic process GO:0034645 224 0.437
Mouse
immune system process GO:0002376 241 0.426
organic cyclic compound biosynthetic process GO:1901362 223 0.421
Human Mouse
regulation of nitrogen compound metabolic process GO:0051171 251 0.391
Human Mouse
heterocycle biosynthetic process GO:0018130 215 0.388
Human Mouse
transcription dna templated GO:0006351 181 0.376
Mouse
developmental growth GO:0048589 166 0.373
heterocycle metabolic process GO:0046483 290 0.370
Human Mouse
regulation of cellular metabolic process GO:0031323 320 0.367
Human Mouse
regulation of macromolecule biosynthetic process GO:0010556 225 0.365
Human Mouse
response to stress GO:0006950 263 0.364
organic substance biosynthetic process GO:1901576 289 0.356
Human Mouse
cellular nitrogen compound metabolic process GO:0034641 290 0.352
Human Mouse
response to chemical GO:0042221 320 0.327
nitrogen compound metabolic process GO:0006807 319 0.324
Human Mouse
growth GO:0040007 174 0.321
organelle organization GO:0006996 227 0.319
generation of neurons GO:0048699 385 0.306
cell motility GO:0048870 244 0.295
regulation of cellular biosynthetic process GO:0031326 245 0.292
Human Mouse
negative regulation of cellular biosynthetic process GO:0031327 55 0.285
Human
positive regulation of cellular process GO:0048522 201 0.275
Mouse
cell migration GO:0016477 237 0.262
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.260
Mouse
regulation of protein metabolic process GO:0051246 56 0.260
negative regulation of macromolecule metabolic process GO:0010605 76 0.259
Human
hematopoietic or lymphoid organ development GO:0048534 191 0.258
macromolecule biosynthetic process GO:0009059 227 0.254
Human Mouse
positive regulation of multicellular organismal process GO:0051240 52 0.254
positive regulation of biological process GO:0048518 253 0.252
Mouse
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.250
Mouse
negative regulation of gene expression GO:0010629 65 0.250
Human
regulation of primary metabolic process GO:0080090 311 0.248
Human Mouse
cellular nitrogen compound biosynthetic process GO:0044271 218 0.240
Human Mouse
locomotion GO:0040011 313 0.239
immune system development GO:0002520 191 0.236
reproductive process GO:0022414 40 0.228
embryo development ending in birth or egg hatching GO:0009792 271 0.224
cellular component biogenesis GO:0044085 178 0.223
Fly
multicellular organism reproduction GO:0032504 35 0.209
adult behavior GO:0030534 2 0.208
Fly
positive regulation of rna biosynthetic process GO:1902680 57 0.205
Mouse
response to temperature stimulus GO:0009266 15 0.205
aging GO:0007568 2 0.204
hemopoiesis GO:0030097 183 0.201
nuclear transport GO:0051169 4 0.197
negative regulation of metabolic process GO:0009892 86 0.197
Human
single organism organelle organization GO:1902589 199 0.196
nucleic acid templated transcription GO:0097659 181 0.191
Mouse
regulation of nucleic acid templated transcription GO:1903506 213 0.190
Mouse
positive regulation of gene expression GO:0010628 71 0.187
Mouse
cellular protein metabolic process GO:0044267 129 0.187
response to abiotic stimulus GO:0009628 122 0.185
regulation of synapse assembly GO:0051963 3 0.184
Fly
neuron development GO:0048666 262 0.184
single organism nuclear import GO:1902593 3 0.173
meiotic nuclear division GO:0007126 4 0.171
protein localization to nucleus GO:0034504 3 0.167
regulation of nervous system development GO:0051960 90 0.164
Fly
nucleocytoplasmic transport GO:0006913 4 0.164
mitotic cell cycle GO:0000278 64 0.163
regulation of multicellular organismal process GO:0051239 277 0.162
Fly
regulation of mrna processing GO:0050684 3 0.158
regulation of growth GO:0040008 42 0.152
Fly
larval behavior GO:0030537 5 0.150
Fly
regulation of rna metabolic process GO:0051252 224 0.144
Human Mouse
covalent chromatin modification GO:0016569 20 0.142
single organism reproductive process GO:0044702 40 0.139
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.138
Human Mouse
positive regulation of macromolecule metabolic process GO:0010604 93 0.137
Mouse
cellular biosynthetic process GO:0044249 286 0.137
Human Mouse
positive regulation of transport GO:0051050 2 0.137
protein import into nucleus GO:0006606 3 0.136
establishment of protein localization to organelle GO:0072594 4 0.130
rna processing GO:0006396 25 0.125
Human
regulation of rna biosynthetic process GO:2001141 213 0.124
Human Mouse
response to oxidative stress GO:0006979 11 0.124
regulation of cell cycle GO:0051726 52 0.121
transcription from rna polymerase ii promoter GO:0006366 80 0.120
Mouse
negative regulation of biosynthetic process GO:0009890 55 0.119
Human
programmed cell death GO:0012501 119 0.117
mrna metabolic process GO:0016071 20 0.116
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.116
Human
negative regulation of cellular metabolic process GO:0031324 77 0.115
Human
regulation of signaling GO:0023051 235 0.115
response to organic substance GO:0010033 153 0.113
transport GO:0006810 220 0.111
stem cell maintenance GO:0019827 4 0.111
multicellular organism growth GO:0035264 4 0.110
response to external stimulus GO:0009605 264 0.108
stem cell differentiation GO:0048863 117 0.105
regionalization GO:0003002 274 0.103
negative regulation of biological process GO:0048519 304 0.100
Human Fly
positive regulation of cellular component biogenesis GO:0044089 3 0.100
single organism metabolic process GO:0044710 217 0.100
regulation of cellular protein metabolic process GO:0032268 52 0.099
regulation of biological quality GO:0065008 263 0.098
Human Fly
cellular response to external stimulus GO:0071496 2 0.098
localization of cell GO:0051674 244 0.097
neuron projection morphogenesis GO:0048812 161 0.096
behavior GO:0007610 74 0.094
positive regulation of developmental process GO:0051094 50 0.094
signal transduction GO:0007165 455 0.094
negative regulation of programmed cell death GO:0043069 58 0.093
neuron differentiation GO:0030182 353 0.092
cellular response to dsrna GO:0071359 1 0.090
single organism transport GO:0044765 206 0.089
embryonic organ morphogenesis GO:0048562 274 0.089
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.088
cell morphogenesis involved in differentiation GO:0000904 195 0.087
establishment of localization GO:0051234 244 0.085
determination of bilateral symmetry GO:0009855 204 0.084
regulation of multicellular organism growth GO:0040014 4 0.083
chromatin modification GO:0016568 21 0.083
head development GO:0060322 303 0.082
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.081
spermatid differentiation GO:0048515 2 0.081
skeletal system development GO:0001501 181 0.081
regulation of nucleocytoplasmic transport GO:0046822 2 0.081
axon development GO:0061564 166 0.081
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.081
regulation of transcription dna templated GO:0006355 213 0.080
Mouse
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.078
rna stabilization GO:0043489 4 0.078
Human
central nervous system neuron differentiation GO:0021953 74 0.078
regulation of cell differentiation GO:0045595 142 0.078
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 10 0.076
neurological system process GO:0050877 62 0.075
nuclear import GO:0051170 3 0.075
negative regulation of developmental process GO:0051093 65 0.075
Fly
female gonad development GO:0008585 4 0.073
single organism behavior GO:0044708 24 0.072
Fly
cell projection morphogenesis GO:0048858 244 0.070
gamete generation GO:0007276 33 0.070
rna biosynthetic process GO:0032774 181 0.069
Human Mouse
larval locomotory behavior GO:0008345 5 0.069
Fly
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.069
Fly
chromosome organization GO:0051276 31 0.069
regulation of multicellular organismal development GO:2000026 223 0.068
Fly
protein acetylation GO:0006473 2 0.068
regulation of cytoplasmic transport GO:1903649 4 0.067
death GO:0016265 121 0.066
embryonic heart tube development GO:0035050 133 0.066
synapse assembly GO:0007416 9 0.065
Fly
taxis GO:0042330 109 0.064
positive regulation of cellular biosynthetic process GO:0031328 68 0.064
Mouse
system process GO:0003008 185 0.063
cell morphogenesis GO:0000902 289 0.062
sensory organ development GO:0007423 393 0.059
brain development GO:0007420 293 0.059
regulation of mrna splicing via spliceosome GO:0048024 3 0.059
negative regulation of ras protein signal transduction GO:0046580 1 0.058
enzyme linked receptor protein signaling pathway GO:0007167 106 0.057
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.057
Human
synaptic growth at neuromuscular junction GO:0051124 2 0.056
Fly
protein import GO:0017038 3 0.055
apoptotic process GO:0006915 116 0.054
pigment cell differentiation GO:0050931 38 0.054
macromolecule modification GO:0043412 111 0.052
regulation of gene expression epigenetic GO:0040029 11 0.052
development of primary female sexual characteristics GO:0046545 4 0.052
regulation of intracellular protein transport GO:0033157 3 0.051
chemotaxis GO:0006935 104 0.051
protein methylation GO:0006479 13 0.051
rna splicing GO:0008380 16 0.050
Human
eye development GO:0001654 277 0.050
regulation of cell communication GO:0010646 232 0.050
regulation of apoptotic process GO:0042981 98 0.050
cellular localization GO:0051641 97 0.050
cell proliferation GO:0008283 80 0.049
cellular respiration GO:0045333 3 0.049
ribonucleoprotein complex subunit organization GO:0071826 8 0.049
protein targeting to nucleus GO:0044744 3 0.049
regulation of synapse organization GO:0050807 3 0.049
Fly
oligodendrocyte differentiation GO:0048709 23 0.048
reproduction GO:0000003 40 0.048
cellular protein modification process GO:0006464 100 0.047
regulation of establishment of protein localization GO:0070201 4 0.047
mrna processing GO:0006397 14 0.047
cellular response to extracellular stimulus GO:0031668 2 0.047
oocyte differentiation GO:0009994 14 0.047
transmembrane transport GO:0055085 120 0.046
multi organism process GO:0051704 134 0.046
Human
mononuclear cell proliferation GO:0032943 1 0.046
ribonucleoprotein complex biogenesis GO:0022613 13 0.045
macromolecular complex subunit organization GO:0043933 74 0.045
cellular component morphogenesis GO:0032989 336 0.045
negative regulation of signaling GO:0023057 96 0.045
macromolecule localization GO:0033036 54 0.044
regulation of epithelial cell proliferation GO:0050678 3 0.044
regulation of signal transduction GO:0009966 225 0.043
locomotory behavior GO:0007626 34 0.043
regulation of programmed cell death GO:0043067 101 0.042
regulation of cell activation GO:0050865 1 0.042
respiratory electron transport chain GO:0022904 2 0.042
homeostatic process GO:0042592 142 0.042
organonitrogen compound metabolic process GO:1901564 74 0.041
amine metabolic process GO:0009308 2 0.041
cell cycle GO:0007049 93 0.040
morphogenesis of an epithelium GO:0002009 333 0.040
developmental process involved in reproduction GO:0003006 27 0.040
positive regulation of cellular catabolic process GO:0031331 3 0.040
female sex differentiation GO:0046660 4 0.040
single organism localization GO:1902578 225 0.039
regulation of protein transport GO:0051223 3 0.039
regulation of anatomical structure morphogenesis GO:0022603 130 0.039
negative regulation of multicellular organismal process GO:0051241 69 0.039
Fly
cognition GO:0050890 1 0.038
internal peptidyl lysine acetylation GO:0018393 2 0.038
defense response GO:0006952 47 0.038
regulation of response to stimulus GO:0048583 269 0.037
cellular response to chemical stimulus GO:0070887 157 0.037
neuron projection guidance GO:0097485 86 0.037
neuroblast proliferation GO:0007405 2 0.037
cell surface receptor signaling pathway GO:0007166 325 0.037
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.037
Human
positive regulation of catabolic process GO:0009896 4 0.037
negative regulation of cell communication GO:0010648 96 0.036
negative regulation of protein phosphorylation GO:0001933 4 0.036
regulation of developmental growth GO:0048638 38 0.036
Fly
modification dependent macromolecule catabolic process GO:0043632 3 0.035
myeloid cell differentiation GO:0030099 86 0.035
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.035
multi organism reproductive process GO:0044703 36 0.035
regulation of immune system process GO:0002682 34 0.035
phagocytosis GO:0006909 3 0.035
peptidyl lysine acetylation GO:0018394 2 0.034
cell projection organization GO:0030030 284 0.034
negative regulation of rna splicing GO:0033119 1 0.034
regulation of protein localization to nucleus GO:1900180 2 0.033
neuron projection extension GO:1990138 45 0.033
compound eye development GO:0048749 2 0.033
positive regulation of metabolic process GO:0009893 108 0.033
Mouse
regulation of binding GO:0051098 3 0.033
regulation of cell proliferation GO:0042127 37 0.033
regulation of glial cell differentiation GO:0045685 4 0.032
leukocyte proliferation GO:0070661 1 0.032
negative regulation of cell death GO:0060548 60 0.032
cellular amine metabolic process GO:0044106 2 0.032
positive regulation of nucleic acid templated transcription GO:1903508 57 0.032
Mouse
apoptotic signaling pathway GO:0097190 23 0.032
negative regulation of secretion GO:0051048 2 0.032
cell death GO:0008219 121 0.032
negative regulation of rna metabolic process GO:0051253 48 0.031
Human
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.031
lymphocyte proliferation GO:0046651 1 0.031
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.031
Human
regulation of rac protein signal transduction GO:0035020 1 0.030
nuclear division GO:0000280 23 0.030
negative regulation of signal transduction GO:0009968 94 0.030
specification of symmetry GO:0009799 204 0.030
regulation of cellular component organization GO:0051128 86 0.030
Fly
dna templated transcription initiation GO:0006352 1 0.030
chromatin organization GO:0006325 22 0.030
extrinsic apoptotic signaling pathway GO:0097191 3 0.029
response to nitrogen compound GO:1901698 19 0.029
embryonic skeletal system development GO:0048706 97 0.029
organic substance transport GO:0071702 58 0.029
electron transport chain GO:0022900 2 0.029
regulation of meiotic cell cycle GO:0051445 1 0.028
mitochondrial transport GO:0006839 2 0.028
dna catabolic process GO:0006308 1 0.028
internal protein amino acid acetylation GO:0006475 2 0.028
regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902175 2 0.028
dsrna fragmentation GO:0031050 1 0.027
protein complex subunit organization GO:0071822 46 0.027
b cell activation GO:0042113 2 0.027
phosphorylation GO:0016310 69 0.027
embryonic heart tube morphogenesis GO:0003143 108 0.027
cell part morphogenesis GO:0032990 246 0.027
regulation of neurogenesis GO:0050767 87 0.026
developmental growth involved in morphogenesis GO:0060560 86 0.026
cellular response to stress GO:0033554 62 0.026
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.026
Mouse
cellular ketone metabolic process GO:0042180 11 0.026
regulation of cell shape GO:0008360 1 0.025
muscle structure development GO:0061061 196 0.025
forebrain cell migration GO:0021885 1 0.025
regulation of protein import into nucleus GO:0042306 2 0.025
negative regulation of cell differentiation GO:0045596 46 0.025
heart looping GO:0001947 94 0.025
muscle tissue development GO:0060537 110 0.025
negative regulation of rna biosynthetic process GO:1902679 45 0.025
Human
determination of left right symmetry GO:0007368 179 0.025
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.025
signal transduction in absence of ligand GO:0038034 1 0.024
protein modification process GO:0036211 100 0.024
positive regulation of apoptotic signaling pathway GO:2001235 1 0.024
negative regulation of apoptotic process GO:0043066 55 0.024
positive regulation of cell activation GO:0050867 1 0.024
regulation of transport GO:0051049 45 0.023
positive regulation of biosynthetic process GO:0009891 68 0.023
Mouse
i kappab kinase nf kappab signaling GO:0007249 4 0.023
camera type eye development GO:0043010 222 0.023
regulation of protein targeting GO:1903533 2 0.023
regulation of cellular amine metabolic process GO:0033238 0 0.023
oxoacid metabolic process GO:0043436 31 0.023
digestive tract morphogenesis GO:0048546 231 0.023
regulation of membrane repolarization GO:0060306 1 0.022
neural crest cell differentiation GO:0014033 72 0.022
chordate embryonic development GO:0043009 271 0.022
developmental pigmentation GO:0048066 48 0.022
stem cell development GO:0048864 82 0.022
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.022
Mouse
protein acylation GO:0043543 3 0.022
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.022
cellular protein catabolic process GO:0044257 4 0.022
mitotic cell cycle process GO:1903047 48 0.022
cell cycle process GO:0022402 53 0.022
histone h3 k4 methylation GO:0051568 2 0.021
negative regulation of transcription dna templated GO:0045892 45 0.021
leukocyte differentiation GO:0002521 25 0.021
modification of morphology or physiology of other organism GO:0035821 4 0.021
Human
cellular response to nutrient levels GO:0031669 2 0.021
maintenance of location GO:0051235 4 0.021
positive regulation of reproductive process GO:2000243 2 0.021
chemosensory behavior GO:0007635 1 0.021
regulation of protein catabolic process GO:0042176 1 0.020
striated muscle tissue development GO:0014706 110 0.020
tube morphogenesis GO:0035239 349 0.020
response to drug GO:0042493 3 0.020
regulation of cell death GO:0010941 103 0.020
microtubule based process GO:0007017 60 0.020
response to organic cyclic compound GO:0014070 51 0.020
axon guidance GO:0007411 86 0.020
determination of heart left right asymmetry GO:0061371 117 0.020
gtp metabolic process GO:0046039 4 0.020
response to cold GO:0009409 4 0.020
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.019
spermatid development GO:0007286 2 0.019
response to oxygen containing compound GO:1901700 55 0.019
stem cell proliferation GO:0072089 4 0.019
carboxylic acid metabolic process GO:0019752 22 0.019
protein phosphorylation GO:0006468 47 0.019
ubiquitin dependent protein catabolic process GO:0006511 3 0.019
embryonic organ development GO:0048568 381 0.019
ribonucleoprotein complex assembly GO:0022618 5 0.019
positive regulation of response to stimulus GO:0048584 80 0.019
regulation of cellular ketone metabolic process GO:0010565 7 0.019
organic acid metabolic process GO:0006082 31 0.019
posttranscriptional regulation of gene expression GO:0010608 14 0.019
Human
metal ion homeostasis GO:0055065 26 0.019
response to uv GO:0009411 3 0.018
cardiac atrium morphogenesis GO:0003209 2 0.018
regulation of cell cycle process GO:0010564 20 0.018
positive regulation of synapse assembly GO:0051965 1 0.018
regulation of cellular protein catabolic process GO:1903362 1 0.018
embryonic limb morphogenesis GO:0030326 2 0.018
regulation of molecular function GO:0065009 70 0.018
tissue homeostasis GO:0001894 25 0.018
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.018
regulation of cellular amino acid metabolic process GO:0006521 0 0.018
sexual reproduction GO:0019953 36 0.018
rna polyadenylation GO:0043631 2 0.018
oogenesis GO:0048477 14 0.018
positive regulation of cell differentiation GO:0045597 30 0.018
mesenchymal cell differentiation GO:0048762 87 0.017
intracellular transport GO:0046907 32 0.017
positive regulation of cellular carbohydrate metabolic process GO:0010676 1 0.017
regulation of localization GO:0032879 104 0.017
autophagy GO:0006914 4 0.017
small molecule metabolic process GO:0044281 77 0.017
germ cell development GO:0007281 22 0.017
rna splicing via transesterification reactions GO:0000375 10 0.017
vasculature development GO:0001944 278 0.017
cell substrate junction assembly GO:0007044 2 0.017
skeletal system morphogenesis GO:0048705 102 0.017
nuclear export GO:0051168 1 0.017
blood vessel development GO:0001568 246 0.016
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.016
viral process GO:0016032 1 0.016
Human
intracellular signal transduction GO:0035556 85 0.016
negative regulation of cell development GO:0010721 26 0.016
mechanosensory behavior GO:0007638 2 0.016
peripheral nervous system development GO:0007422 55 0.016
multi organism cellular process GO:0044764 2 0.016
Human
regulation of protein binding GO:0043393 3 0.016
cytoskeleton organization GO:0007010 96 0.016
dna templated transcription elongation GO:0006354 3 0.016
positive regulation of translation GO:0045727 1 0.015
organelle assembly GO:0070925 110 0.015
positive regulation of molecular function GO:0044093 33 0.015
positive regulation of protein metabolic process GO:0051247 23 0.015
negative regulation of cytoplasmic transport GO:1903650 2 0.015
angiogenesis GO:0001525 158 0.015
regulation of rho protein signal transduction GO:0035023 2 0.015
regeneration GO:0031099 91 0.015
phosphorus metabolic process GO:0006793 109 0.015
ovarian follicle development GO:0001541 2 0.014
positive regulation of nervous system development GO:0051962 25 0.014
forebrain development GO:0030900 96 0.014
positive regulation of signal transduction GO:0009967 56 0.014
regulation of oligodendrocyte differentiation GO:0048713 1 0.014
oxidation reduction process GO:0055114 41 0.014
mesenchyme development GO:0060485 127 0.014
regulation of reproductive process GO:2000241 4 0.014
female gamete generation GO:0007292 14 0.014
carbohydrate derivative metabolic process GO:1901135 61 0.014
pigmentation GO:0043473 85 0.014
fin regeneration GO:0031101 51 0.014
cation homeostasis GO:0055080 33 0.014
blood vessel morphogenesis GO:0048514 216 0.014
transmission of nerve impulse GO:0019226 19 0.014
cellular macromolecular complex assembly GO:0034622 24 0.014
regulation of protein complex assembly GO:0043254 3 0.014
melanin metabolic process GO:0006582 2 0.014
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 4 0.014
Human
neuromuscular synaptic transmission GO:0007274 2 0.013
Fly
ion homeostasis GO:0050801 41 0.013
anterior posterior pattern specification GO:0009952 152 0.013
regulation of organelle organization GO:0033043 29 0.013
positive regulation of cell cycle GO:0045787 3 0.013
histone modification GO:0016570 20 0.013
rna 3 end processing GO:0031123 2 0.013
negative regulation of multi organism process GO:0043901 3 0.013
Human
protein localization GO:0008104 40 0.013
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.013
osteoclast differentiation GO:0030316 1 0.013
locomotor rhythm GO:0045475 3 0.013
axis specification GO:0009798 43 0.013
neuron death GO:0070997 21 0.013
negative regulation of intracellular protein transport GO:0090317 3 0.013
columnar cuboidal epithelial cell differentiation GO:0002065 38 0.013
calcium ion homeostasis GO:0055074 19 0.013
cell substrate adhesion GO:0031589 4 0.013
spliceosomal complex assembly GO:0000245 1 0.013
sympathetic nervous system development GO:0048485 3 0.013
centrosome cycle GO:0007098 1 0.013
mrna 3 end processing GO:0031124 2 0.013
cellular response to starvation GO:0009267 1 0.012
positive regulation of cellular amine metabolic process GO:0033240 0 0.012
proteasomal protein catabolic process GO:0010498 2 0.012
convergent extension GO:0060026 118 0.012
positive regulation of carbohydrate metabolic process GO:0045913 1 0.012
muscle organ development GO:0007517 101 0.012
hepaticobiliary system development GO:0061008 98 0.012
production of small rna involved in gene silencing by rna GO:0070918 1 0.012
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.012
gtp catabolic process GO:0006184 2 0.012
positive regulation of epithelial cell proliferation GO:0050679 1 0.012
mrna splicing via spliceosome GO:0000398 10 0.012
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.012
ras protein signal transduction GO:0007265 7 0.012
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.012
multicellular organismal signaling GO:0035637 22 0.012
positive regulation of rna metabolic process GO:0051254 59 0.012
Mouse
negative regulation of protein transport GO:0051224 3 0.012
proteolysis GO:0006508 38 0.012
regulation of dendrite morphogenesis GO:0048814 3 0.012
amino acid transport GO:0006865 2 0.012
axonogenesis GO:0007409 152 0.012
tissue regeneration GO:0042246 74 0.012
positive regulation of cellular metabolic process GO:0031325 94 0.011
Mouse
liver development GO:0001889 96 0.011
regulation of cytokine production GO:0001817 3 0.011
negative regulation of kinase activity GO:0033673 4 0.011

tardbp disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.308
Human
nervous system disease DOID:863 0 0.140
Human
cancer DOID:162 0 0.118
disease of cellular proliferation DOID:14566 0 0.118
organ system cancer DOID:0050686 0 0.118
motor neuron disease DOID:231 0 0.054
Human
central nervous system disease DOID:331 0 0.054
Human
amyotrophic lateral sclerosis DOID:332 0 0.054
Human
neurodegenerative disease DOID:1289 0 0.054
Human
myopathy DOID:423 0 0.016
muscular disease DOID:0080000 0 0.016
heart disease DOID:114 0 0.016
cardiomyopathy DOID:0050700 0 0.016
intrinsic cardiomyopathy DOID:0060036 0 0.016
cardiovascular system disease DOID:1287 0 0.016
musculoskeletal system disease DOID:17 0 0.016
muscle tissue disease DOID:66 0 0.016