Danio rerio

0 known processes

zgc:162965

zgc:162965

(Aliases: im:7149534,fam83d)

zgc:162965 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cytokinesis GO:0000910 3 0.185
spindle assembly involved in mitosis GO:0090307 1 0.172
cellular protein catabolic process GO:0044257 4 0.140
larval development GO:0002164 2 0.138
cytoskeleton dependent cytokinesis GO:0061640 3 0.132
establishment of protein localization to organelle GO:0072594 4 0.120
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.115
signal transduction GO:0007165 455 0.109
centrosome duplication GO:0051298 1 0.108
blood vessel development GO:0001568 246 0.096
meiosis i GO:0007127 1 0.093
modification dependent protein catabolic process GO:0019941 3 0.092
nucleocytoplasmic transport GO:0006913 4 0.092
mitotic nuclear division GO:0007067 18 0.091
protein targeting to nucleus GO:0044744 3 0.091
organelle assembly GO:0070925 110 0.090
regulation of chromosome segregation GO:0051983 1 0.088
protein localization to nucleus GO:0034504 3 0.088
aging GO:0007568 2 0.084
single organism nuclear import GO:1902593 3 0.079
single organism organelle organization GO:1902589 199 0.077
ubiquitin dependent protein catabolic process GO:0006511 3 0.077
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.076
spindle assembly GO:0051225 2 0.074
negative regulation of nuclear division GO:0051784 3 0.071
regulation of synapse organization GO:0050807 3 0.069
female meiotic division GO:0007143 2 0.065
regulation of protein import into nucleus GO:0042306 2 0.063
protein metabolic process GO:0019538 183 0.061
regulation of protein ubiquitination GO:0031396 3 0.061
regulation of protein catabolic process GO:0042176 1 0.061
negative regulation of protein import into nucleus GO:0042308 2 0.060
single organism metabolic process GO:0044710 217 0.059
modification dependent macromolecule catabolic process GO:0043632 3 0.059
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.058
organelle organization GO:0006996 227 0.057
regulation of dna replication GO:0006275 3 0.057
phagocytosis GO:0006909 3 0.054
regulation of nucleocytoplasmic transport GO:0046822 2 0.052
negative regulation of mitosis GO:0045839 3 0.052
negative regulation of catabolic process GO:0009895 3 0.051
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.050
negative regulation of protein localization to nucleus GO:1900181 2 0.050
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.048
single organism localization GO:1902578 225 0.048
meiotic cell cycle process GO:1903046 3 0.047
hematopoietic or lymphoid organ development GO:0048534 191 0.047
proteasomal protein catabolic process GO:0010498 2 0.047
nuclear transport GO:0051169 4 0.047
regulation of dendrite development GO:0050773 3 0.046
compound eye development GO:0048749 2 0.045
centrosome organization GO:0051297 1 0.045
protein import GO:0017038 3 0.044
stem cell proliferation GO:0072089 4 0.043
g2 m transition of mitotic cell cycle GO:0000086 4 0.043
gene expression GO:0010467 252 0.042
regulation of cell communication GO:0010646 232 0.042
multicellular organism growth GO:0035264 4 0.041
maintenance of location GO:0051235 4 0.041
cell cycle g2 m phase transition GO:0044839 4 0.041
negative regulation of protein phosphorylation GO:0001933 4 0.041
protein import into nucleus GO:0006606 3 0.041
negative regulation of biological process GO:0048519 304 0.040
nucleic acid templated transcription GO:0097659 181 0.039
nuclear import GO:0051170 3 0.039
oocyte maturation GO:0001556 4 0.039
mitotic cytokinesis GO:0000281 3 0.038
positive regulation of catabolic process GO:0009896 4 0.038
positive regulation of cellular catabolic process GO:0031331 3 0.038
negative regulation of cellular catabolic process GO:0031330 3 0.038
regulation of cytoplasmic transport GO:1903649 4 0.037
positive regulation of cell cycle GO:0045787 3 0.037
somatic muscle development GO:0007525 4 0.036
regulation of primary metabolic process GO:0080090 311 0.035
cell surface receptor signaling pathway GO:0007166 325 0.035
angiogenesis GO:0001525 158 0.035
meiotic chromosome segregation GO:0045132 3 0.035
regulation of protein targeting GO:1903533 2 0.035
centrosome cycle GO:0007098 1 0.034
regulation of protein transport GO:0051223 3 0.034
biosynthetic process GO:0009058 294 0.034
death GO:0016265 121 0.033
stem cell maintenance GO:0019827 4 0.033
histone phosphorylation GO:0016572 2 0.032
cellular component assembly GO:0022607 170 0.032
generation of neurons GO:0048699 385 0.032
immune system process GO:0002376 241 0.032
negative regulation of protein transport GO:0051224 3 0.032
cellular component movement GO:0006928 335 0.032
negative regulation of cellular process GO:0048523 283 0.032
blood vessel morphogenesis GO:0048514 216 0.031
regulation of signal transduction GO:0009966 225 0.031
positive regulation of transport GO:0051050 2 0.031
heart development GO:0007507 313 0.030
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.029
regulation of cellular metabolic process GO:0031323 320 0.029
brain development GO:0007420 293 0.029
protein polyubiquitination GO:0000209 4 0.028
cell death GO:0008219 121 0.028
vasculature development GO:0001944 278 0.027
regulation of protein localization to nucleus GO:1900180 2 0.026
establishment of localization GO:0051234 244 0.026
positive regulation of chromosome segregation GO:0051984 1 0.026
regulation of cellular protein catabolic process GO:1903362 1 0.026
mitotic cell cycle embryonic GO:0045448 2 0.025
regulation of nitrogen compound metabolic process GO:0051171 251 0.025
cellular ketone metabolic process GO:0042180 11 0.025
response to drug GO:0042493 3 0.025
negative regulation of cytoplasmic transport GO:1903650 2 0.025
response to external stimulus GO:0009605 264 0.025
negative regulation of protein kinase activity GO:0006469 4 0.025
apoptotic process GO:0006915 116 0.024
cellular aromatic compound metabolic process GO:0006725 295 0.024
cellular component assembly involved in morphogenesis GO:0010927 107 0.024
regulation of cellular amino acid metabolic process GO:0006521 0 0.024
regulation of apoptotic process GO:0042981 98 0.024
response to external biotic stimulus GO:0043207 97 0.024
regulation of establishment of protein localization GO:0070201 4 0.024
germ line stem cell maintenance GO:0030718 2 0.024
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.024
cell cycle arrest GO:0007050 1 0.023
positive regulation of chromosome organization GO:2001252 1 0.023
response to stress GO:0006950 263 0.023
nucleobase containing compound metabolic process GO:0006139 274 0.023
cellular amino acid metabolic process GO:0006520 7 0.023
neuron development GO:0048666 262 0.023
macromolecule modification GO:0043412 111 0.023
cell projection organization GO:0030030 284 0.023
rna metabolic process GO:0016070 219 0.023
regulation of cell death GO:0010941 103 0.023
regulation of macromolecule metabolic process GO:0060255 317 0.023
regulation of cellular ketone metabolic process GO:0010565 7 0.022
regulation of intracellular protein transport GO:0033157 3 0.022
positive regulation of cellular amine metabolic process GO:0033240 0 0.022
microtubule organizing center organization GO:0031023 1 0.022
gland development GO:0048732 143 0.022
cellular amine metabolic process GO:0044106 2 0.021
negative regulation of intracellular transport GO:0032387 3 0.021
guanosine containing compound catabolic process GO:1901069 2 0.021
negative regulation of macromolecule metabolic process GO:0010605 76 0.021
negative regulation of intracellular protein transport GO:0090317 3 0.021
macromolecule biosynthetic process GO:0009059 227 0.021
cytoskeleton organization GO:0007010 96 0.021
regulation of cell projection assembly GO:0060491 4 0.021
transport GO:0006810 220 0.021
regulation of reactive oxygen species metabolic process GO:2000377 2 0.021
negative regulation of kinase activity GO:0033673 4 0.021
cell part morphogenesis GO:0032990 246 0.021
positive regulation of biological process GO:0048518 253 0.020
regulation of gene expression GO:0010468 265 0.020
regulation of cellular amine metabolic process GO:0033238 0 0.020
cellular protein modification process GO:0006464 100 0.020
cellular response to extracellular stimulus GO:0031668 2 0.020
protein dephosphorylation GO:0006470 3 0.020
regulation of signaling GO:0023051 235 0.020
protein heterooligomerization GO:0051291 1 0.020
single organism transport GO:0044765 206 0.020
meiotic spindle organization GO:0000212 1 0.020
b cell activation GO:0042113 2 0.019
heterocycle metabolic process GO:0046483 290 0.019
protein modification process GO:0036211 100 0.019
positive regulation of cellular process GO:0048522 201 0.019
regulation of meiotic cell cycle GO:0051445 1 0.019
leukocyte homeostasis GO:0001776 2 0.019
regulation of programmed cell death GO:0043067 101 0.019
mitotic cell cycle GO:0000278 64 0.019
meiotic nuclear division GO:0007126 4 0.019
regulation of rna metabolic process GO:0051252 224 0.019
guanosine containing compound metabolic process GO:1901068 4 0.019
cellular response to external stimulus GO:0071496 2 0.019
protein polymerization GO:0051258 4 0.019
mitotic metaphase plate congression GO:0007080 1 0.019
antimicrobial humoral response GO:0019730 2 0.019
positive regulation of cell division GO:0051781 2 0.019
transcription dna templated GO:0006351 181 0.018
positive regulation of dna metabolic process GO:0051054 1 0.018
g2 dna damage checkpoint GO:0031572 3 0.018
organic substance biosynthetic process GO:1901576 289 0.018
immune system development GO:0002520 191 0.018
cellular localization GO:0051641 97 0.018
cell cycle process GO:0022402 53 0.018
regulation of biological quality GO:0065008 263 0.018
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.018
negative regulation of signaling GO:0023057 96 0.018
positive regulation of cellular metabolic process GO:0031325 94 0.018
intracellular signal transduction GO:0035556 85 0.018
cellular component morphogenesis GO:0032989 336 0.017
growth GO:0040007 174 0.017
regulation of binding GO:0051098 3 0.017
cellular nitrogen compound biosynthetic process GO:0044271 218 0.017
positive regulation of metabolic process GO:0009893 108 0.017
regulation of multicellular organismal development GO:2000026 223 0.017
organic acid metabolic process GO:0006082 31 0.017
cleavage furrow formation GO:0036089 2 0.017
leukocyte proliferation GO:0070661 1 0.017
carboxylic acid metabolic process GO:0019752 22 0.017
epithelial cell differentiation GO:0030855 116 0.017
localization of cell GO:0051674 244 0.017
cell migration GO:0016477 237 0.017
nuclear migration GO:0007097 3 0.017
macromolecular complex disassembly GO:0032984 1 0.017
protein complex assembly GO:0006461 30 0.017
multi organism process GO:0051704 134 0.017
negative regulation of cellular metabolic process GO:0031324 77 0.017
cellular nitrogen compound metabolic process GO:0034641 290 0.017
cellular macromolecule metabolic process GO:0044260 391 0.016
single fertilization GO:0007338 3 0.016
protein complex disassembly GO:0043241 1 0.016
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.016
regulation of cellular biosynthetic process GO:0031326 245 0.016
regulation of multicellular organism growth GO:0040014 4 0.016
establishment of rna localization GO:0051236 3 0.016
regulation of protein metabolic process GO:0051246 56 0.016
peptidyl threonine phosphorylation GO:0018107 1 0.016
cellular component disassembly GO:0022411 1 0.016
microtubule cytoskeleton organization GO:0000226 33 0.016
programmed cell death GO:0012501 119 0.016
gtp metabolic process GO:0046039 4 0.016
cellular component biogenesis GO:0044085 178 0.016
embryo development ending in birth or egg hatching GO:0009792 271 0.016
fertilization GO:0009566 3 0.016
regulation of cell motility GO:2000145 46 0.016
rna 3 end processing GO:0031123 2 0.016
microtubule based process GO:0007017 60 0.015
positive regulation of cytoskeleton organization GO:0051495 3 0.015
positive regulation of nucleoside metabolic process GO:0045979 1 0.015
cell aging GO:0007569 2 0.015
negative regulation of chromosome organization GO:2001251 1 0.015
adult behavior GO:0030534 2 0.015
regulation of synaptic plasticity GO:0048167 1 0.015
gtp catabolic process GO:0006184 2 0.015
cell cycle GO:0007049 93 0.015
positive regulation of macromolecule metabolic process GO:0010604 93 0.015
mitotic cell cycle process GO:1903047 48 0.015
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.015
interspecies interaction between organisms GO:0044419 4 0.015
positive regulation of camp biosynthetic process GO:0030819 2 0.015
eye development GO:0001654 277 0.014
stem cell differentiation GO:0048863 117 0.014
regulation of purine nucleotide catabolic process GO:0033121 2 0.014
mitochondrion organization GO:0007005 4 0.014
aromatic compound biosynthetic process GO:0019438 217 0.014
cellular macromolecule biosynthetic process GO:0034645 224 0.014
cell projection morphogenesis GO:0048858 244 0.014
nucleic acid metabolic process GO:0090304 244 0.014
regulation of transcription dna templated GO:0006355 213 0.014
regulation of macromolecule biosynthetic process GO:0010556 225 0.014
regulation of cell differentiation GO:0045595 142 0.014
autophagy GO:0006914 4 0.014
regulation of response to stimulus GO:0048583 269 0.014
regulation of multicellular organismal process GO:0051239 277 0.014
regulation of mitotic cell cycle GO:0007346 25 0.014
regulation of localization GO:0032879 104 0.014
regulation of nucleic acid templated transcription GO:1903506 213 0.014
response to chemical GO:0042221 320 0.014
regulation of protein binding GO:0043393 3 0.014
neuron differentiation GO:0030182 353 0.014
cellular protein metabolic process GO:0044267 129 0.014
negative regulation of cell cycle process GO:0010948 9 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.014
negative regulation of mapk cascade GO:0043409 4 0.014
establishment of organelle localization GO:0051656 45 0.014
response to biotic stimulus GO:0009607 97 0.014
oxoacid metabolic process GO:0043436 31 0.014
rna localization GO:0006403 4 0.014
lymphocyte proliferation GO:0046651 1 0.013
negative regulation of nucleic acid templated transcription GO:1903507 45 0.013
locomotion GO:0040011 313 0.013
proteolysis GO:0006508 38 0.013
response to abiotic stimulus GO:0009628 122 0.013
regulation of metabolic process GO:0019222 359 0.013
regulation of neuron projection development GO:0010975 40 0.013
peptidyl threonine modification GO:0018210 1 0.013
double strand break repair GO:0006302 3 0.013
production of molecular mediator of immune response GO:0002440 2 0.013
regulation of cell shape GO:0008360 1 0.013
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.013
reciprocal dna recombination GO:0035825 1 0.013
regulation of nervous system development GO:0051960 90 0.013
membrane invagination GO:0010324 1 0.013
regulation of cellular component organization GO:0051128 86 0.013
wnt signaling pathway GO:0016055 80 0.013
macromolecule localization GO:0033036 54 0.013
male meiosis GO:0007140 2 0.013
neuronal stem cell maintenance GO:0097150 2 0.012
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.012
response to oxygen levels GO:0070482 25 0.012
striated muscle cell development GO:0055002 108 0.012
head development GO:0060322 303 0.012
negative regulation of metabolic process GO:0009892 86 0.012
regulation of protein complex disassembly GO:0043244 1 0.012
positive regulation of rna biosynthetic process GO:1902680 57 0.012
nucleobase containing compound biosynthetic process GO:0034654 205 0.012
regulation of stem cell proliferation GO:0072091 2 0.012
rna transport GO:0050658 2 0.012
cell proliferation GO:0008283 80 0.012
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 1 0.012
regulation of neural precursor cell proliferation GO:2000177 3 0.012
regulation of protein polymerization GO:0032271 2 0.012
organic substance transport GO:0071702 58 0.012
digestive system development GO:0055123 289 0.012
regulation of microtubule cytoskeleton organization GO:0070507 3 0.012
phosphate containing compound metabolic process GO:0006796 108 0.012
embryonic organ development GO:0048568 381 0.012
central nervous system development GO:0007417 387 0.012
muscle cell development GO:0055001 115 0.012
protein complex subunit organization GO:0071822 46 0.012
cellular protein complex disassembly GO:0043624 1 0.012
rna biosynthetic process GO:0032774 181 0.012
regulation of proteolysis GO:0030162 24 0.012
negative regulation of cell communication GO:0010648 96 0.012
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.012
organic substance catabolic process GO:1901575 28 0.012
negative regulation of response to stimulus GO:0048585 104 0.012
regulation of neurogenesis GO:0050767 87 0.011
peptidyl tyrosine dephosphorylation GO:0035335 1 0.011
cell motility GO:0048870 244 0.011
negative regulation of cell division GO:0051782 4 0.011
positive regulation of histone modification GO:0031058 1 0.011
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.011
tube closure GO:0060606 1 0.011
negative regulation of developmental process GO:0051093 65 0.011
regulation of nucleotide catabolic process GO:0030811 2 0.011
cell fate commitment GO:0045165 99 0.011
cellular biosynthetic process GO:0044249 286 0.011
stem cell fate commitment GO:0048865 1 0.011
peptidyl serine phosphorylation GO:0018105 1 0.011
regulation of cellular protein metabolic process GO:0032268 52 0.011
chordate embryonic development GO:0043009 271 0.011
negative regulation of dna metabolic process GO:0051053 4 0.011
regulation of protein complex assembly GO:0043254 3 0.011
mitotic dna integrity checkpoint GO:0044774 4 0.011
skeletal system morphogenesis GO:0048705 102 0.011
negative regulation of cell cycle GO:0045786 14 0.011
embryonic skeletal system development GO:0048706 97 0.011
tissue remodeling GO:0048771 4 0.011
neuron projection development GO:0031175 180 0.011
actin filament based process GO:0030029 64 0.011
neuroblast proliferation GO:0007405 2 0.011
stem cell fate determination GO:0048867 1 0.011
organelle localization GO:0051640 49 0.011
homeostatic process GO:0042592 142 0.011
negative regulation of cell death GO:0060548 60 0.011
microtubule depolymerization GO:0007019 1 0.011
negative regulation of programmed cell death GO:0043069 58 0.011
regulation of rna biosynthetic process GO:2001141 213 0.011
embryonic organ morphogenesis GO:0048562 274 0.011
mrna 3 end processing GO:0031124 2 0.011
organelle transport along microtubule GO:0072384 1 0.011
regulation of nucleoside metabolic process GO:0009118 2 0.011
sensory organ development GO:0007423 393 0.010
regulation of cell activation GO:0050865 1 0.010
organonitrogen compound metabolic process GO:1901564 74 0.010
regulation of developmental process GO:0050793 247 0.010
amine metabolic process GO:0009308 2 0.010
regulation of cell development GO:0060284 100 0.010
somatic stem cell maintenance GO:0035019 1 0.010
negative regulation of catalytic activity GO:0043086 21 0.010
meiosis ii GO:0007135 1 0.010
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.010
mononuclear cell proliferation GO:0032943 1 0.010
regulation of organelle assembly GO:1902115 4 0.010
cell cycle g1 s phase transition GO:0044843 1 0.010
positive regulation of nucleotide catabolic process GO:0030813 1 0.010
post embryonic organ development GO:0048569 4 0.010
female gonad development GO:0008585 4 0.010
proximal distal pattern formation GO:0009954 1 0.010
regulation of cardiac muscle tissue development GO:0055024 1 0.010
small gtpase mediated signal transduction GO:0007264 8 0.010
muscle structure development GO:0061061 196 0.010
positive regulation of cellular component biogenesis GO:0044089 3 0.010
cellular response to decreased oxygen levels GO:0036294 1 0.010
anterior posterior pattern specification GO:0009952 152 0.010
organic cyclic compound metabolic process GO:1901360 301 0.010
regulation of heart growth GO:0060420 2 0.010

zgc:162965 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.018
disease of cellular proliferation DOID:14566 0 0.018
disease of metabolism DOID:0014667 0 0.011