Danio rerio

2 known processes

galca

galactosylceramidase a

(Aliases: galcl,zgc:92561,si:ch211-199l3.4,galc)

galca biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
digestive tract development GO:0048565 265 0.298
signal transduction GO:0007165 455 0.135
digestive tract morphogenesis GO:0048546 231 0.132
exocytosis GO:0006887 1 0.126
cell surface receptor signaling pathway GO:0007166 325 0.117
neuron differentiation GO:0030182 353 0.114
immune system process GO:0002376 241 0.105
regulation of cellular metabolic process GO:0031323 320 0.102
gastrulation GO:0007369 208 0.097
positive regulation of transport GO:0051050 2 0.077
chordate embryonic development GO:0043009 271 0.075
regulation of cell communication GO:0010646 232 0.071
regionalization GO:0003002 274 0.069
morphogenesis of an epithelium GO:0002009 333 0.066
regulation of metabolic process GO:0019222 359 0.063
cellular protein catabolic process GO:0044257 4 0.062
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.062
regulation of synapse assembly GO:0051963 3 0.059
digestive system development GO:0055123 289 0.058
larval development GO:0002164 2 0.058
cell motility GO:0048870 244 0.057
heterocycle metabolic process GO:0046483 290 0.057
tube morphogenesis GO:0035239 349 0.056
positive regulation of secretion by cell GO:1903532 1 0.055
negative regulation of biological process GO:0048519 304 0.054
cognition GO:0050890 1 0.054
positive regulation of cellular component biogenesis GO:0044089 3 0.054
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.051
erk1 and erk2 cascade GO:0070371 4 0.050
brain development GO:0007420 293 0.050
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.050
cell morphogenesis involved in differentiation GO:0000904 195 0.050
phosphorus metabolic process GO:0006793 109 0.049
synaptic growth at neuromuscular junction GO:0051124 2 0.048
regulation of multicellular organismal process GO:0051239 277 0.048
nitrogen compound metabolic process GO:0006807 319 0.048
organelle organization GO:0006996 227 0.047
localization of cell GO:0051674 244 0.047
regulation of wound healing GO:0061041 2 0.047
specification of symmetry GO:0009799 204 0.046
hemopoiesis GO:0030097 183 0.045
regulation of erk1 and erk2 cascade GO:0070372 4 0.044
hematopoietic or lymphoid organ development GO:0048534 191 0.043
regulation of protein transport GO:0051223 3 0.043
regulation of macromolecule metabolic process GO:0060255 317 0.043
regulation of primary metabolic process GO:0080090 311 0.043
generation of neurons GO:0048699 385 0.042
regulation of developmental process GO:0050793 247 0.042
protein modification process GO:0036211 100 0.041
positive regulation of secretion GO:0051047 1 0.041
organonitrogen compound metabolic process GO:1901564 74 0.041
regulation of signaling GO:0023051 235 0.041
regulation of synapse organization GO:0050807 3 0.040
response to chemical GO:0042221 320 0.040
cellular component morphogenesis GO:0032989 336 0.040
single organism localization GO:1902578 225 0.040
heart development GO:0007507 313 0.039
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.038
regulation of gene expression GO:0010468 265 0.038
phosphate containing compound metabolic process GO:0006796 108 0.038
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.038
cell migration GO:0016477 237 0.038
system process GO:0003008 185 0.037
nucleobase containing compound metabolic process GO:0006139 274 0.037
cell morphogenesis GO:0000902 289 0.036
cell projection morphogenesis GO:0048858 244 0.036
cellular component movement GO:0006928 335 0.036
modification dependent macromolecule catabolic process GO:0043632 3 0.036
regulation of signal transduction GO:0009966 225 0.036
nucleic acid metabolic process GO:0090304 244 0.036
embryonic organ development GO:0048568 381 0.035
single organism organelle organization GO:1902589 199 0.035
positive regulation of exocytosis GO:0045921 1 0.035
gene expression GO:0010467 252 0.035
regulation of biosynthetic process GO:0009889 250 0.034
cellular aromatic compound metabolic process GO:0006725 295 0.034
establishment of protein localization to organelle GO:0072594 4 0.033
cellular nitrogen compound metabolic process GO:0034641 290 0.033
regulation of cell shape GO:0008360 1 0.033
central nervous system development GO:0007417 387 0.033
negative regulation of cellular process GO:0048523 283 0.032
regulation of macromolecule biosynthetic process GO:0010556 225 0.032
cell projection organization GO:0030030 284 0.032
regulation of response to stimulus GO:0048583 269 0.031
sensory organ development GO:0007423 393 0.031
cellular macromolecule metabolic process GO:0044260 391 0.030
stem cell differentiation GO:0048863 117 0.030
head development GO:0060322 303 0.030
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.029
locomotion GO:0040011 313 0.029
epithelial tube morphogenesis GO:0060562 148 0.029
proteasomal protein catabolic process GO:0010498 2 0.028
adult behavior GO:0030534 2 0.028
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.028
response to external stimulus GO:0009605 264 0.028
embryonic organ morphogenesis GO:0048562 274 0.028
modification dependent protein catabolic process GO:0019941 3 0.028
maintenance of location GO:0051235 4 0.028
cellular response to organic substance GO:0071310 105 0.028
organic cyclic compound metabolic process GO:1901360 301 0.028
ras protein signal transduction GO:0007265 7 0.028
rna metabolic process GO:0016070 219 0.027
cellular macromolecule biosynthetic process GO:0034645 224 0.027
cellular amine metabolic process GO:0044106 2 0.026
determination of bilateral symmetry GO:0009855 204 0.026
regulation of protein complex assembly GO:0043254 3 0.026
axonogenesis GO:0007409 152 0.026
epiboly GO:0090504 41 0.026
positive regulation of cell cycle GO:0045787 3 0.026
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.026
neuron projection development GO:0031175 180 0.025
oxoacid metabolic process GO:0043436 31 0.025
small molecule catabolic process GO:0044282 3 0.025
gtp catabolic process GO:0006184 2 0.025
regulation of establishment of protein localization GO:0070201 4 0.025
cell migration involved in heart development GO:0060973 22 0.025
protein secretion GO:0009306 1 0.025
axon development GO:0061564 166 0.024
atp catabolic process GO:0006200 4 0.024
myeloid cell differentiation GO:0030099 86 0.024
nucleic acid templated transcription GO:0097659 181 0.024
positive regulation of response to stimulus GO:0048584 80 0.024
immune system development GO:0002520 191 0.024
positive regulation of cellular process GO:0048522 201 0.024
regulation of nitrogen compound metabolic process GO:0051171 251 0.024
amine metabolic process GO:0009308 2 0.024
small molecule metabolic process GO:0044281 77 0.024
positive regulation of wound healing GO:0090303 1 0.024
convergent extension GO:0060026 118 0.023
heart morphogenesis GO:0003007 156 0.023
ribonucleoside monophosphate catabolic process GO:0009158 4 0.023
mitochondrion organization GO:0007005 4 0.023
regulation of oocyte development GO:0060281 3 0.023
small gtpase mediated signal transduction GO:0007264 8 0.023
regulation of cellular amino acid metabolic process GO:0006521 0 0.023
regulation of exocytosis GO:0017157 1 0.022
regulation of protein polymerization GO:0032271 2 0.022
cellular amino acid metabolic process GO:0006520 7 0.022
regulation of transcription dna templated GO:0006355 213 0.022
nucleobase containing compound biosynthetic process GO:0034654 205 0.022
macromolecule modification GO:0043412 111 0.022
macromolecule biosynthetic process GO:0009059 227 0.022
regulation of neurogenesis GO:0050767 87 0.022
multi organism process GO:0051704 134 0.022
microtubule based process GO:0007017 60 0.022
transport GO:0006810 220 0.021
guanosine containing compound metabolic process GO:1901068 4 0.021
regulation of localization GO:0032879 104 0.021
positive regulation of signaling GO:0023056 56 0.021
regulation of cell development GO:0060284 100 0.021
protein metabolic process GO:0019538 183 0.021
cytokinesis GO:0000910 3 0.021
carboxylic acid metabolic process GO:0019752 22 0.021
gtp metabolic process GO:0046039 4 0.021
response to drug GO:0042493 3 0.021
aging GO:0007568 2 0.021
startle response GO:0001964 4 0.020
purine nucleoside monophosphate catabolic process GO:0009128 4 0.020
protein complex disassembly GO:0043241 1 0.020
guanosine containing compound catabolic process GO:1901069 2 0.020
carbohydrate derivative metabolic process GO:1901135 61 0.020
cellular component assembly GO:0022607 170 0.020
leukocyte homeostasis GO:0001776 2 0.020
protein phosphorylation GO:0006468 47 0.020
morphogenesis of an epithelial sheet GO:0002011 49 0.020
rna biosynthetic process GO:0032774 181 0.020
positive regulation of cell communication GO:0010647 56 0.020
neuron projection morphogenesis GO:0048812 161 0.020
organic acid metabolic process GO:0006082 31 0.020
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.020
phosphorylation GO:0016310 69 0.020
actin polymerization or depolymerization GO:0008154 2 0.020
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.020
protein polymerization GO:0051258 4 0.020
meiotic nuclear division GO:0007126 4 0.020
convergent extension involved in gastrulation GO:0060027 71 0.020
retina development in camera type eye GO:0060041 146 0.020
taxis GO:0042330 109 0.020
regulation of immune system process GO:0002682 34 0.020
regulation of cell activation GO:0050865 1 0.020
phagocytosis engulfment GO:0006911 1 0.020
meiosis i GO:0007127 1 0.020
production of molecular mediator of immune response GO:0002440 2 0.019
response to glucose GO:0009749 3 0.019
cellular protein metabolic process GO:0044267 129 0.019
peptidyl threonine phosphorylation GO:0018107 1 0.019
positive regulation of catabolic process GO:0009896 4 0.019
skeletal system morphogenesis GO:0048705 102 0.019
peptide metabolic process GO:0006518 1 0.019
neuron development GO:0048666 262 0.019
ubiquitin dependent protein catabolic process GO:0006511 3 0.019
embryonic heart tube development GO:0035050 133 0.019
cellular component disassembly GO:0022411 1 0.018
vasculature development GO:0001944 278 0.018
regulation of cytokine production GO:0001817 3 0.018
enzyme linked receptor protein signaling pathway GO:0007167 106 0.018
response to stress GO:0006950 263 0.018
cellular nitrogen compound biosynthetic process GO:0044271 218 0.018
anterior posterior pattern specification GO:0009952 152 0.018
regulation of rho protein signal transduction GO:0035023 2 0.018
intracellular signal transduction GO:0035556 85 0.018
regulation of molecular function GO:0065009 70 0.018
regulation of biological quality GO:0065008 263 0.018
homeostatic process GO:0042592 142 0.018
regulation of nucleic acid templated transcription GO:1903506 213 0.018
response to biotic stimulus GO:0009607 97 0.018
establishment of localization GO:0051234 244 0.018
blood vessel morphogenesis GO:0048514 216 0.018
regulation of multicellular organismal development GO:2000026 223 0.018
neurological system process GO:0050877 62 0.018
embryonic heart tube morphogenesis GO:0003143 108 0.018
positive regulation of nucleoside metabolic process GO:0045979 1 0.017
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.017
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.017
regulation of cellular biosynthetic process GO:0031326 245 0.017
positive regulation of cell activation GO:0050867 1 0.017
transcription dna templated GO:0006351 181 0.017
regulation of reactive oxygen species metabolic process GO:2000377 2 0.017
eye development GO:0001654 277 0.017
determination of heart left right asymmetry GO:0061371 117 0.017
positive regulation of cytokine production GO:0001819 2 0.017
regulation of filopodium assembly GO:0051489 2 0.016
response to endogenous stimulus GO:0009719 83 0.016
regulation of cellular component organization GO:0051128 86 0.016
rho protein signal transduction GO:0007266 5 0.016
regulation of cellular ketone metabolic process GO:0010565 7 0.016
negative regulation of protein complex assembly GO:0031333 1 0.016
protein localization to nucleus GO:0034504 3 0.016
transcription from rna polymerase ii promoter GO:0006366 80 0.016
regulation of cellular amine metabolic process GO:0033238 0 0.016
regulation of cell differentiation GO:0045595 142 0.016
positive regulation of cellular amine metabolic process GO:0033240 0 0.016
regulation of phosphorus metabolic process GO:0051174 43 0.016
regulation of reproductive process GO:2000241 4 0.016
stem cell proliferation GO:0072089 4 0.016
cellular biosynthetic process GO:0044249 286 0.016
synaptic vesicle localization GO:0097479 1 0.016
regulation of leukocyte mediated immunity GO:0002703 1 0.016
phagocytosis GO:0006909 3 0.016
cellular response to chemical stimulus GO:0070887 157 0.015
regulation of intracellular signal transduction GO:1902531 57 0.015
negative regulation of cytokine production GO:0001818 1 0.015
regulation of nucleoside metabolic process GO:0009118 2 0.015
response to bacterium GO:0009617 58 0.015
cellular response to biotic stimulus GO:0071216 3 0.015
fertilization GO:0009566 3 0.015
negative regulation of kinase activity GO:0033673 4 0.015
blood vessel development GO:0001568 246 0.015
regulation of nucleotide catabolic process GO:0030811 2 0.015
regulation of microtubule cytoskeleton organization GO:0070507 3 0.015
meiotic cell cycle process GO:1903046 3 0.015
single organism transport GO:0044765 206 0.015
chemotaxis GO:0006935 104 0.015
regulation of nervous system development GO:0051960 90 0.015
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.015
peptidyl serine modification GO:0018209 2 0.015
single organism metabolic process GO:0044710 217 0.014
cellular localization GO:0051641 97 0.014
positive regulation of signal transduction GO:0009967 56 0.014
membrane invagination GO:0010324 1 0.014
response to monosaccharide GO:0034284 3 0.014
positive regulation of cellular catabolic process GO:0031331 3 0.014
negative regulation of mapk cascade GO:0043409 4 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.014
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.014
cellular response to lipopolysaccharide GO:0071222 3 0.014
neuroblast proliferation GO:0007405 2 0.014
gland development GO:0048732 143 0.014
peptidyl serine phosphorylation GO:0018105 1 0.014
autophagy GO:0006914 4 0.014
synaptic transmission GO:0007268 35 0.014
cellular response to growth factor stimulus GO:0071363 39 0.014
aromatic compound biosynthetic process GO:0019438 217 0.014
stem cell fate commitment GO:0048865 1 0.014
regulation of stem cell proliferation GO:0072091 2 0.014
heterocycle biosynthetic process GO:0018130 215 0.014
neurotransmitter transport GO:0006836 2 0.014
cytoskeleton organization GO:0007010 96 0.013
peptidyl threonine modification GO:0018210 1 0.013
microtubule cytoskeleton organization GO:0000226 33 0.013
cellular response to external stimulus GO:0071496 2 0.013
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.013
regulation of purine nucleotide catabolic process GO:0033121 2 0.013
positive regulation of apoptotic signaling pathway GO:2001235 1 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.013
determination of left right symmetry GO:0007368 179 0.013
organic cyclic compound biosynthetic process GO:1901362 223 0.013
cellular ketone metabolic process GO:0042180 11 0.013
nuclear import GO:0051170 3 0.013
reproduction GO:0000003 40 0.013
response to wounding GO:0009611 116 0.013
microtubule polymerization or depolymerization GO:0031109 3 0.013
organic substance biosynthetic process GO:1901576 289 0.013
regulation of protein ubiquitination GO:0031396 3 0.013
positive regulation of multi organism process GO:0043902 3 0.013
organelle localization GO:0051640 49 0.013
regulation of metal ion transport GO:0010959 4 0.013
single organism nuclear import GO:1902593 3 0.013
epithelial cell differentiation GO:0030855 116 0.013
response to other organism GO:0051707 97 0.013
negative regulation of signal transduction GO:0009968 94 0.013
protein import GO:0017038 3 0.012
negative regulation of protein phosphorylation GO:0001933 4 0.012
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.012
regulation of protein catabolic process GO:0042176 1 0.012
neuron neuron synaptic transmission GO:0007270 1 0.012
cell projection assembly GO:0030031 64 0.012
protein targeting to nucleus GO:0044744 3 0.012
establishment of localization in cell GO:0051649 77 0.012
regulation of dendrite development GO:0050773 3 0.012
cellular protein modification process GO:0006464 100 0.012
cellular response to endogenous stimulus GO:0071495 68 0.012
cell cycle g1 s phase transition GO:0044843 1 0.012
regulation of meiotic cell cycle GO:0051445 1 0.012
cellular amide metabolic process GO:0043603 4 0.012
nuclear migration GO:0007097 3 0.012
regulation of catalytic activity GO:0050790 55 0.012
response to hexose GO:0009746 3 0.012
nucleoside monophosphate catabolic process GO:0009125 4 0.012
regulation of rna metabolic process GO:0051252 224 0.012
negative regulation of secretion GO:0051048 2 0.012
inositol lipid mediated signaling GO:0048017 2 0.012
rna localization GO:0006403 4 0.012
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.012
biosynthetic process GO:0009058 294 0.012
negative regulation of signaling GO:0023057 96 0.012
mitotic cell cycle process GO:1903047 48 0.012
macromolecular complex disassembly GO:0032984 1 0.012
regulation of blood coagulation GO:0030193 1 0.012
response to organic substance GO:0010033 153 0.011
lipid storage GO:0019915 1 0.011
regulation of rna biosynthetic process GO:2001141 213 0.011
myeloid leukocyte mediated immunity GO:0002444 1 0.011
establishment of synaptic vesicle localization GO:0097480 1 0.011
single organism cellular localization GO:1902580 46 0.011
regulation of calcium ion transport GO:0051924 2 0.011
regulation of neural precursor cell proliferation GO:2000177 3 0.011
positive regulation of immune effector process GO:0002699 3 0.011
defense response GO:0006952 47 0.011
cell part morphogenesis GO:0032990 246 0.011
nucleocytoplasmic transport GO:0006913 4 0.011
ameboidal type cell migration GO:0001667 143 0.011
negative regulation of protein transport GO:0051224 3 0.011
stem cell maintenance GO:0019827 4 0.011
protein localization to plasma membrane GO:0072659 1 0.011
interspecies interaction between organisms GO:0044419 4 0.011
carboxylic acid catabolic process GO:0046395 3 0.011
negative regulation of protein kinase activity GO:0006469 4 0.011
multicellular organism growth GO:0035264 4 0.011
regulation of gtp catabolic process GO:0033124 2 0.011
cytokinetic process GO:0032506 2 0.011
i kappab kinase nf kappab signaling GO:0007249 4 0.011
negative regulation of catabolic process GO:0009895 3 0.011
regulation of phosphate metabolic process GO:0019220 43 0.011
microtubule polymerization GO:0046785 2 0.011
negative regulation of cellular catabolic process GO:0031330 3 0.010
establishment of organelle localization GO:0051656 45 0.010
organelle fusion GO:0048284 3 0.010
regulation of protein metabolic process GO:0051246 56 0.010
response to abiotic stimulus GO:0009628 122 0.010
wound healing GO:0042060 90 0.010
neural crest cell migration GO:0001755 42 0.010
response to carbohydrate GO:0009743 3 0.010
positive regulation of biological process GO:0048518 253 0.010
regulation of cell migration GO:0030334 40 0.010
protein dephosphorylation GO:0006470 3 0.010

galca disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.018
disease of anatomical entity DOID:7 0 0.018
cancer DOID:162 0 0.017
disease of cellular proliferation DOID:14566 0 0.017
organ system cancer DOID:0050686 0 0.017
nervous system disease DOID:863 0 0.015