Danio rerio

0 known processes

zgc:110116

zgc:110116

(Aliases: psmd5,im:7137623)

zgc:110116 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular protein catabolic process GO:0044257 4 0.385
larval development GO:0002164 2 0.291
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.284
ubiquitin dependent protein catabolic process GO:0006511 3 0.275
modification dependent protein catabolic process GO:0019941 3 0.270
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.233
proteasomal protein catabolic process GO:0010498 2 0.224
modification dependent macromolecule catabolic process GO:0043632 3 0.220
cellular macromolecule metabolic process GO:0044260 391 0.163
nucleobase containing compound metabolic process GO:0006139 274 0.113
response to stress GO:0006950 263 0.109
Fly
embryo development ending in birth or egg hatching GO:0009792 271 0.104
Worm
negative regulation of biological process GO:0048519 304 0.104
ribonucleoside monophosphate catabolic process GO:0009158 4 0.103
nucleoside monophosphate catabolic process GO:0009125 4 0.096
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.088
positive regulation of biological process GO:0048518 253 0.085
nitrogen compound metabolic process GO:0006807 319 0.079
gene expression GO:0010467 252 0.079
maintenance of location GO:0051235 4 0.079
positive regulation of catabolic process GO:0009896 4 0.079
apoptotic process GO:0006915 116 0.076
cellular aromatic compound metabolic process GO:0006725 295 0.074
negative regulation of cellular process GO:0048523 283 0.073
regulation of protein catabolic process GO:0042176 1 0.073
single organism localization GO:1902578 225 0.070
heterocycle metabolic process GO:0046483 290 0.068
aging GO:0007568 2 0.067
positive regulation of cellular catabolic process GO:0031331 3 0.061
establishment of localization GO:0051234 244 0.060
lipid storage GO:0019915 1 0.060
cell death GO:0008219 121 0.055
regulation of macromolecule metabolic process GO:0060255 317 0.053
spindle assembly GO:0051225 2 0.053
eye development GO:0001654 277 0.052
cellular macromolecule biosynthetic process GO:0034645 224 0.052
regulation of cellular metabolic process GO:0031323 320 0.051
meiotic cell cycle process GO:1903046 3 0.049
death GO:0016265 121 0.047
regulation of cell death GO:0010941 103 0.046
cellular component biogenesis GO:0044085 178 0.045
regionalization GO:0003002 274 0.044
positive regulation of metabolic process GO:0009893 108 0.044
meiotic chromosome segregation GO:0045132 3 0.044
single fertilization GO:0007338 3 0.044
microtubule based process GO:0007017 60 0.043
cellular protein modification process GO:0006464 100 0.043
cellular component assembly GO:0022607 170 0.043
single organism organelle organization GO:1902589 199 0.042
protein metabolic process GO:0019538 183 0.042
single organism metabolic process GO:0044710 217 0.042
response to external stimulus GO:0009605 264 0.041
negative regulation of nuclear division GO:0051784 3 0.040
cellular protein metabolic process GO:0044267 129 0.040
macromolecular complex disassembly GO:0032984 1 0.040
positive regulation of cellular component biogenesis GO:0044089 3 0.039
sensory organ development GO:0007423 393 0.039
positive regulation of cellular process GO:0048522 201 0.039
transport GO:0006810 220 0.037
negative regulation of cellular metabolic process GO:0031324 77 0.037
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.037
regulation of primary metabolic process GO:0080090 311 0.037
i kappab kinase nf kappab signaling GO:0007249 4 0.037
protein polymerization GO:0051258 4 0.037
macromolecular complex subunit organization GO:0043933 74 0.036
cellular nitrogen compound metabolic process GO:0034641 290 0.036
programmed cell death GO:0012501 119 0.036
mitochondrion organization GO:0007005 4 0.036
cell cell recognition GO:0009988 1 0.036
purine nucleoside monophosphate catabolic process GO:0009128 4 0.036
establishment of protein localization to organelle GO:0072594 4 0.035
cellular component disassembly GO:0022411 1 0.034
nucleobase containing compound biosynthetic process GO:0034654 205 0.034
organic substance biosynthetic process GO:1901576 289 0.033
regulation of metabolic process GO:0019222 359 0.033
organic cyclic compound metabolic process GO:1901360 301 0.033
protein import GO:0017038 3 0.033
meiosis i GO:0007127 1 0.032
cellular response to dna damage stimulus GO:0006974 24 0.032
Fly
regulation of chromosome segregation GO:0051983 1 0.032
regulation of protein transport GO:0051223 3 0.031
regulation of protein localization to nucleus GO:1900180 2 0.031
peptidyl lysine acetylation GO:0018394 2 0.031
cellular macromolecule catabolic process GO:0044265 12 0.031
regulation of gene expression GO:0010468 265 0.030
regulation of programmed cell death GO:0043067 101 0.030
regulation of nitrogen compound metabolic process GO:0051171 251 0.030
regulation of cellular amine metabolic process GO:0033238 0 0.029
regulation of multicellular organism growth GO:0040014 4 0.029
regulation of cellular protein catabolic process GO:1903362 1 0.029
regulation of meiotic cell cycle GO:0051445 1 0.029
positive regulation of transport GO:0051050 2 0.029
biosynthetic process GO:0009058 294 0.029
chromosome organization GO:0051276 31 0.028
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.028
single organism nuclear import GO:1902593 3 0.028
single organism transport GO:0044765 206 0.028
locomotion GO:0040011 313 0.028
atp catabolic process GO:0006200 4 0.028
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.028
immune system process GO:0002376 241 0.028
nucleocytoplasmic transport GO:0006913 4 0.028
protein localization to nucleus GO:0034504 3 0.028
cellular catabolic process GO:0044248 27 0.028
fertilization GO:0009566 3 0.027
multicellular organism growth GO:0035264 4 0.027
cellular response to stress GO:0033554 62 0.027
Fly
macromolecular complex assembly GO:0065003 35 0.027
protein complex disassembly GO:0043241 1 0.027
response to biotic stimulus GO:0009607 97 0.027
negative regulation of protein phosphorylation GO:0001933 4 0.027
cell projection organization GO:0030030 284 0.026
cytoskeleton dependent cytokinesis GO:0061640 3 0.026
regulation of protein complex assembly GO:0043254 3 0.026
proteolysis GO:0006508 38 0.026
regulation of macromolecule biosynthetic process GO:0010556 225 0.026
cellular response to nutrient levels GO:0031669 2 0.025
signal transduction GO:0007165 455 0.025
cellular response to external stimulus GO:0071496 2 0.025
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.025
heterocycle biosynthetic process GO:0018130 215 0.024
regulation of establishment of protein localization GO:0070201 4 0.024
regulation of binding GO:0051098 3 0.024
nucleic acid metabolic process GO:0090304 244 0.024
regulation of protein targeting GO:1903533 2 0.024
protein modification process GO:0036211 100 0.024
negative regulation of protein import into nucleus GO:0042308 2 0.024
response to chemical GO:0042221 320 0.024
cellular amine metabolic process GO:0044106 2 0.023
regulation of mitochondrion organization GO:0010821 1 0.023
positive regulation of apoptotic signaling pathway GO:2001235 1 0.023
cellular nitrogen compound biosynthetic process GO:0044271 218 0.023
protein targeting to nucleus GO:0044744 3 0.023
regulation of apoptotic process GO:0042981 98 0.023
positive regulation of cell cycle GO:0045787 3 0.023
cellular biosynthetic process GO:0044249 286 0.023
response to topologically incorrect protein GO:0035966 2 0.023
organic substance catabolic process GO:1901575 28 0.023
rna metabolic process GO:0016070 219 0.023
positive regulation of gtp catabolic process GO:0033126 1 0.022
female sex differentiation GO:0046660 4 0.022
aromatic compound biosynthetic process GO:0019438 217 0.022
response to drug GO:0042493 3 0.022
protein import into nucleus GO:0006606 3 0.022
autophagy GO:0006914 4 0.022
regulation of nucleoside metabolic process GO:0009118 2 0.022
protein acetylation GO:0006473 2 0.022
intracellular signal transduction GO:0035556 85 0.022
macromolecule modification GO:0043412 111 0.022
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.022
dna templated transcription initiation GO:0006352 1 0.022
organelle assembly GO:0070925 110 0.022
regulation of signaling GO:0023051 235 0.022
macromolecule catabolic process GO:0009057 15 0.021
regulation of cellular component organization GO:0051128 86 0.021
multi organism process GO:0051704 134 0.021
developmental programmed cell death GO:0010623 4 0.021
positive regulation of nucleoside metabolic process GO:0045979 1 0.021
camera type eye development GO:0043010 222 0.021
regulation of biological quality GO:0065008 263 0.021
catabolic process GO:0009056 32 0.021
cellular localization GO:0051641 97 0.021
amine metabolic process GO:0009308 2 0.021
nucleic acid templated transcription GO:0097659 181 0.021
meiotic nuclear division GO:0007126 4 0.021
negative regulation of transcription dna templated GO:0045892 45 0.020
regulation of cell communication GO:0010646 232 0.020
positive regulation of protein complex assembly GO:0031334 2 0.020
organelle organization GO:0006996 227 0.020
blood vessel morphogenesis GO:0048514 216 0.020
cytokinesis GO:0000910 3 0.020
regulation of intracellular protein transport GO:0033157 3 0.020
cell part morphogenesis GO:0032990 246 0.020
chordate embryonic development GO:0043009 271 0.020
anterior posterior pattern specification GO:0009952 152 0.020
phosphate containing compound metabolic process GO:0006796 108 0.019
gtp metabolic process GO:0046039 4 0.019
chromosome organization involved in meiosis GO:0070192 1 0.019
neuron development GO:0048666 262 0.019
establishment of localization in cell GO:0051649 77 0.019
microtubule cytoskeleton organization GO:0000226 33 0.019
regulation of rna biosynthetic process GO:2001141 213 0.019
regulation of signal transduction GO:0009966 225 0.019
nuclear transport GO:0051169 4 0.019
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.019
negative regulation of signal transduction GO:0009968 94 0.019
rna transport GO:0050658 2 0.019
regulation of cellular amino acid metabolic process GO:0006521 0 0.019
cellular component movement GO:0006928 335 0.019
positive regulation of cytokine production GO:0001819 2 0.018
vasculature development GO:0001944 278 0.018
positive regulation of nucleotide catabolic process GO:0030813 1 0.018
protein secretion GO:0009306 1 0.018
cell projection morphogenesis GO:0048858 244 0.018
positive regulation of cellular metabolic process GO:0031325 94 0.018
regulation of protein binding GO:0043393 3 0.018
negative regulation of mitosis GO:0045839 3 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.018
response to organic substance GO:0010033 153 0.018
ovulation cycle GO:0042698 2 0.018
regulation of protein ubiquitination GO:0031396 3 0.018
compound eye development GO:0048749 2 0.017
negative regulation of protein localization to nucleus GO:1900181 2 0.017
protein dephosphorylation GO:0006470 3 0.017
regulation of purine nucleotide catabolic process GO:0033121 2 0.017
spindle assembly involved in mitosis GO:0090307 1 0.016
regulation of response to stimulus GO:0048583 269 0.016
regulation of protein import into nucleus GO:0042306 2 0.016
negative regulation of macromolecule metabolic process GO:0010605 76 0.016
small molecule metabolic process GO:0044281 77 0.016
protein complex assembly GO:0006461 30 0.016
macromolecule localization GO:0033036 54 0.016
erk1 and erk2 cascade GO:0070371 4 0.016
negative regulation of cytoplasmic transport GO:1903650 2 0.016
regulation of multicellular organismal development GO:2000026 223 0.016
response to other organism GO:0051707 97 0.016
cell morphogenesis GO:0000902 289 0.016
organonitrogen compound metabolic process GO:1901564 74 0.015
phosphorus metabolic process GO:0006793 109 0.015
organic cyclic compound biosynthetic process GO:1901362 223 0.015
regulation of protein complex disassembly GO:0043244 1 0.015
regulation of cellular biosynthetic process GO:0031326 245 0.015
microtubule polymerization or depolymerization GO:0031109 3 0.015
cellular response to starvation GO:0009267 1 0.015
mitotic g2 dna damage checkpoint GO:0007095 3 0.015
regulation of cell activation GO:0050865 1 0.015
developmental growth GO:0048589 166 0.015
regulation of nucleotide catabolic process GO:0030811 2 0.015
cellular protein complex assembly GO:0043623 19 0.015
embryonic organ development GO:0048568 381 0.015
negative regulation of catabolic process GO:0009895 3 0.015
internal protein amino acid acetylation GO:0006475 2 0.015
central nervous system development GO:0007417 387 0.015
negative regulation of metabolic process GO:0009892 86 0.015
negative regulation of response to stimulus GO:0048585 104 0.015
neuron differentiation GO:0030182 353 0.015
internal peptidyl lysine acetylation GO:0018393 2 0.015
positive regulation of dna metabolic process GO:0051054 1 0.015
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.014
positive regulation of cell activation GO:0050867 1 0.014
nucleobase containing compound transport GO:0015931 2 0.014
angiogenesis GO:0001525 158 0.014
negative regulation of signaling GO:0023057 96 0.014
negative regulation of cell communication GO:0010648 96 0.014
regulation of dna templated transcription elongation GO:0032784 3 0.014
protein localization GO:0008104 40 0.014
cellular amino acid metabolic process GO:0006520 7 0.014
generation of neurons GO:0048699 385 0.014
regulation of metal ion transport GO:0010959 4 0.014
mitotic g2 m transition checkpoint GO:0044818 3 0.014
regulation of multicellular organismal process GO:0051239 277 0.014
carbohydrate derivative metabolic process GO:1901135 61 0.014
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.014
dorsal ventral pattern formation GO:0009953 125 0.014
regulation of rna metabolic process GO:0051252 224 0.014
positive regulation of cellular amine metabolic process GO:0033240 0 0.014
blood vessel development GO:0001568 246 0.014
interspecies interaction between organisms GO:0044419 4 0.014
mrna 3 end processing GO:0031124 2 0.014
regulation of biosynthetic process GO:0009889 250 0.014
cellular response to extracellular stimulus GO:0031668 2 0.014
regulation of cytokine production GO:0001817 3 0.013
regulation of nucleic acid templated transcription GO:1903506 213 0.013
regulation of cellular ketone metabolic process GO:0010565 7 0.013
extrinsic apoptotic signaling pathway GO:0097191 3 0.013
organic substance transport GO:0071702 58 0.013
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.013
negative regulation of protein transport GO:0051224 3 0.013
homeostatic process GO:0042592 142 0.013
rna localization GO:0006403 4 0.013
dna templated transcription elongation GO:0006354 3 0.013
regulation of transcription dna templated GO:0006355 213 0.013
growth GO:0040007 174 0.013
cellular response to organic substance GO:0071310 105 0.013
cell migration GO:0016477 237 0.013
nucleoside phosphate metabolic process GO:0006753 28 0.013
positive regulation of macromolecule metabolic process GO:0010604 93 0.013
negative regulation of intracellular protein transport GO:0090317 3 0.013
toxin transport GO:1901998 2 0.013
negative regulation of mapk cascade GO:0043409 4 0.013
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.013
positive regulation of gtpase activity GO:0043547 1 0.013
carboxylic acid metabolic process GO:0019752 22 0.013
protein heterooligomerization GO:0051291 1 0.013
system process GO:0003008 185 0.013
macromolecule biosynthetic process GO:0009059 227 0.013
protein depolymerization GO:0051261 1 0.012
gtp catabolic process GO:0006184 2 0.012
regulation of cellular protein metabolic process GO:0032268 52 0.012
apoptotic process involved in morphogenesis GO:0060561 2 0.012
production of molecular mediator of immune response GO:0002440 2 0.012
embryonic digestive tract development GO:0048566 4 0.012
phagocytosis GO:0006909 3 0.012
negative regulation of gene expression GO:0010629 65 0.012
establishment of organelle localization GO:0051656 45 0.012
regulation of gtpase activity GO:0043087 2 0.012
regulation of developmental process GO:0050793 247 0.012
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.012
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.012
small molecule catabolic process GO:0044282 3 0.012
nuclear migration GO:0007097 3 0.012
hemopoiesis GO:0030097 183 0.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.012
cellular carbohydrate metabolic process GO:0044262 4 0.012
phagocytosis engulfment GO:0006911 1 0.012
cellular protein complex disassembly GO:0043624 1 0.011
oxoacid metabolic process GO:0043436 31 0.011
regulation of gtp catabolic process GO:0033124 2 0.011
negative regulation of chromosome organization GO:2001251 1 0.011
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.011
mitotic cell cycle GO:0000278 64 0.011
negative regulation of biosynthetic process GO:0009890 55 0.011
negative regulation of intracellular transport GO:0032387 3 0.011
negative regulation of protein kinase activity GO:0006469 4 0.011
response to external biotic stimulus GO:0043207 97 0.011
rna 3 end processing GO:0031123 2 0.011
immune system development GO:0002520 191 0.011
energy reserve metabolic process GO:0006112 2 0.011
response to alkaloid GO:0043279 2 0.011
stem cell proliferation GO:0072089 4 0.011
positive regulation of chromosome organization GO:2001252 1 0.011
regulation of stem cell proliferation GO:0072091 2 0.011
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.011
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.011
b cell activation GO:0042113 2 0.011
regulation of nucleocytoplasmic transport GO:0046822 2 0.011
regulation of circadian rhythm GO:0042752 4 0.011
regulation of cell shape GO:0008360 1 0.011
negative regulation of cell death GO:0060548 60 0.011
oocyte anterior posterior axis specification GO:0007314 4 0.011
regulation of erk1 and erk2 cascade GO:0070372 4 0.011
response to endogenous stimulus GO:0009719 83 0.010
regulation of proteolysis GO:0030162 24 0.010
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.010
small gtpase mediated signal transduction GO:0007264 8 0.010
development of primary female sexual characteristics GO:0046545 4 0.010
protein stabilization GO:0050821 2 0.010
negative regulation of cellular catabolic process GO:0031330 3 0.010
axonogenesis GO:0007409 152 0.010
regulation of cytoplasmic transport GO:1903649 4 0.010
neuromuscular synaptic transmission GO:0007274 2 0.010
positive regulation of biosynthetic process GO:0009891 68 0.010
regulation of microtubule cytoskeleton organization GO:0070507 3 0.010
regulation of synapse assembly GO:0051963 3 0.010
ncrna catabolic process GO:0034661 1 0.010
mitotic nuclear division GO:0007067 18 0.010
negative regulation of kinase activity GO:0033673 4 0.010
head development GO:0060322 303 0.010
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.010
positive regulation of cytoskeleton organization GO:0051495 3 0.010

zgc:110116 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.051
nervous system disease DOID:863 0 0.035
disease of metabolism DOID:0014667 0 0.025
inherited metabolic disorder DOID:655 0 0.025
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
organ system cancer DOID:0050686 0 0.012
central nervous system disease DOID:331 0 0.010
neurodegenerative disease DOID:1289 0 0.010