Danio rerio

0 known processes

zp2.2

zona pellucida glycoprotein 2.2

(Aliases: MGC158204,zp2,wu:fj99c12,zp2a,fj99c12)

zp2.2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of exocytosis GO:0045921 1 0.502
positive regulation of calcium ion dependent exocytosis GO:0045956 1 0.442
cell cell recognition GO:0009988 1 0.400
metal ion transport GO:0030001 58 0.381
negative regulation of biological process GO:0048519 304 0.366
negative regulation of cellular process GO:0048523 283 0.350
regulation of primary metabolic process GO:0080090 311 0.324
regulation of ion transmembrane transport GO:0034765 18 0.316
regulation of metal ion transport GO:0010959 4 0.303
signal transduction GO:0007165 455 0.265
embryonic organ development GO:0048568 381 0.253
regulation of transmembrane transport GO:0034762 18 0.253
inorganic cation transmembrane transport GO:0098662 50 0.239
embryonic organ morphogenesis GO:0048562 274 0.226
positive regulation of transport GO:0051050 2 0.221
inorganic ion transmembrane transport GO:0098660 57 0.219
calcium ion import GO:0070509 4 0.218
central nervous system development GO:0007417 387 0.214
single fertilization GO:0007338 3 0.198
heart morphogenesis GO:0003007 156 0.188
regulation of cellular metabolic process GO:0031323 320 0.188
organic cyclic compound metabolic process GO:1901360 301 0.184
regulation of multicellular organismal process GO:0051239 277 0.183
single organism localization GO:1902578 225 0.174
transmembrane transport GO:0055085 120 0.167
regulation of calcium ion dependent exocytosis GO:0017158 1 0.165
tube morphogenesis GO:0035239 349 0.153
single organism transport GO:0044765 206 0.153
heart development GO:0007507 313 0.144
nucleobase containing compound metabolic process GO:0006139 274 0.141
transcription dna templated GO:0006351 181 0.138
ion transmembrane transport GO:0034220 91 0.135
negative regulation of reproductive process GO:2000242 3 0.132
regulation of transcription dna templated GO:0006355 213 0.129
response to nutrient GO:0007584 3 0.124
ion transport GO:0006811 114 0.123
oocyte maturation GO:0001556 4 0.121
cellular macromolecule biosynthetic process GO:0034645 224 0.121
regulation of localization GO:0032879 104 0.115
positive regulation of biological process GO:0048518 253 0.112
endodermal cell fate specification GO:0001714 17 0.110
regulation of calcium ion transport GO:0051924 2 0.108
positive regulation of cellular process GO:0048522 201 0.106
cell motility GO:0048870 244 0.104
biosynthetic process GO:0009058 294 0.104
epithelial tube morphogenesis GO:0060562 148 0.103
regulation of metabolic process GO:0019222 359 0.103
regulation of reproductive process GO:2000241 4 0.103
larval development GO:0002164 2 0.096
determination of bilateral symmetry GO:0009855 204 0.096
rna metabolic process GO:0016070 219 0.095
positive regulation of reproductive process GO:2000243 2 0.095
positive regulation of macromolecule metabolic process GO:0010604 93 0.094
intracellular signal transduction GO:0035556 85 0.091
nitrogen compound metabolic process GO:0006807 319 0.089
regulation of rna metabolic process GO:0051252 224 0.089
digestive tract morphogenesis GO:0048546 231 0.086
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.086
regulation of macromolecule metabolic process GO:0060255 317 0.086
immune system process GO:0002376 241 0.084
cellular macromolecule metabolic process GO:0044260 391 0.082
rna biosynthetic process GO:0032774 181 0.081
transcription from rna polymerase ii promoter GO:0006366 80 0.080
heterocycle metabolic process GO:0046483 290 0.079
maintenance of location GO:0051235 4 0.078
neuroblast differentiation GO:0014016 1 0.077
cellular component movement GO:0006928 335 0.077
cation transmembrane transport GO:0098655 65 0.076
macromolecule biosynthetic process GO:0009059 227 0.075
cation transport GO:0006812 81 0.073
calcium ion dependent exocytosis GO:0017156 1 0.072
embryonic heart tube morphogenesis GO:0003143 108 0.072
heterocycle biosynthetic process GO:0018130 215 0.071
gastrulation GO:0007369 208 0.071
negative regulation of transcription dna templated GO:0045892 45 0.071
digestive tract development GO:0048565 265 0.070
cellular aromatic compound metabolic process GO:0006725 295 0.068
nucleobase containing compound biosynthetic process GO:0034654 205 0.067
cellular nitrogen compound metabolic process GO:0034641 290 0.066
vasculature development GO:0001944 278 0.066
positive regulation of secretion by cell GO:1903532 1 0.065
sensory organ development GO:0007423 393 0.065
regulation of biosynthetic process GO:0009889 250 0.065
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.063
organic substance biosynthetic process GO:1901576 289 0.062
heart looping GO:0001947 94 0.061
regulation of anatomical structure morphogenesis GO:0022603 130 0.061
protein metabolic process GO:0019538 183 0.060
fertilization GO:0009566 3 0.060
positive regulation of cellular metabolic process GO:0031325 94 0.059
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.059
regulation of transport GO:0051049 45 0.058
regulation of nucleic acid templated transcription GO:1903506 213 0.058
regulation of developmental process GO:0050793 247 0.058
gene expression GO:0010467 252 0.056
blood vessel development GO:0001568 246 0.055
sexual reproduction GO:0019953 36 0.055
regulation of ion transport GO:0043269 22 0.055
cellular biosynthetic process GO:0044249 286 0.055
regulation of transmembrane transporter activity GO:0022898 2 0.055
embryonic heart tube development GO:0035050 133 0.054
female sex differentiation GO:0046660 4 0.053
blood vessel morphogenesis GO:0048514 216 0.052
aging GO:0007568 2 0.052
lipid storage GO:0019915 1 0.051
calcium ion transmembrane transport GO:0070588 13 0.050
regulation of response to stimulus GO:0048583 269 0.050
eye development GO:0001654 277 0.050
positive regulation of multi organism process GO:0043902 3 0.046
cellular localization GO:0051641 97 0.046
muscle cell development GO:0055001 115 0.046
regulation of rna biosynthetic process GO:2001141 213 0.046
embryo development ending in birth or egg hatching GO:0009792 271 0.045
regulation of signal transduction GO:0009966 225 0.043
regulation of gene expression GO:0010468 265 0.043
spermatid development GO:0007286 2 0.042
brain development GO:0007420 293 0.041
transport GO:0006810 220 0.041
cellular protein metabolic process GO:0044267 129 0.041
regulation of signaling GO:0023051 235 0.041
neuroblast proliferation GO:0007405 2 0.041
sodium ion transport GO:0006814 24 0.040
positive regulation of response to stimulus GO:0048584 80 0.039
divalent inorganic cation transport GO:0072511 21 0.039
camera type eye development GO:0043010 222 0.038
regulation of cytokine production GO:0001817 3 0.038
morphogenesis of an epithelium GO:0002009 333 0.038
aromatic compound biosynthetic process GO:0019438 217 0.037
determination of left right symmetry GO:0007368 179 0.036
adult behavior GO:0030534 2 0.036
specification of symmetry GO:0009799 204 0.036
regulation of molecular function GO:0065009 70 0.035
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.034
response to antibiotic GO:0046677 1 0.034
regulation of protein metabolic process GO:0051246 56 0.034
epiboly GO:0090504 41 0.033
regulation of macromolecule biosynthetic process GO:0010556 225 0.033
stem cell division GO:0017145 1 0.032
divalent metal ion transport GO:0070838 20 0.032
cellular nitrogen compound biosynthetic process GO:0044271 218 0.032
determination of heart left right asymmetry GO:0061371 117 0.031
regulation of nitrogen compound metabolic process GO:0051171 251 0.030
regulation of exocytosis GO:0017157 1 0.030
localization of cell GO:0051674 244 0.030
regulation of programmed cell death GO:0043067 101 0.030
meiotic cell cycle process GO:1903046 3 0.029
establishment of localization GO:0051234 244 0.029
meiotic chromosome segregation GO:0045132 3 0.029
response to chemical GO:0042221 320 0.029
spemann organizer formation at the embryonic shield GO:0060063 2 0.029
regulation of cell activation GO:0050865 1 0.029
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.029
head development GO:0060322 303 0.028
positive regulation of secretion GO:0051047 1 0.028
neuron differentiation GO:0030182 353 0.028
nucleic acid metabolic process GO:0090304 244 0.028
positive regulation of cellular component biogenesis GO:0044089 3 0.028
organic cyclic compound biosynthetic process GO:1901362 223 0.028
axonogenesis GO:0007409 152 0.027
meiotic nuclear division GO:0007126 4 0.026
ameboidal type cell migration GO:0001667 143 0.026
morphogenesis of an epithelial sheet GO:0002011 49 0.026
nucleic acid templated transcription GO:0097659 181 0.026
ovarian follicle development GO:0001541 2 0.026
female gonad development GO:0008585 4 0.025
macromolecule modification GO:0043412 111 0.025
regulation of sodium ion transport GO:0002028 2 0.025
sensory organ morphogenesis GO:0090596 200 0.025
calcium ion transport GO:0006816 18 0.025
regulation of immune response GO:0050776 14 0.025
epithelial cell differentiation GO:0030855 116 0.025
regulation of cellular protein metabolic process GO:0032268 52 0.025
multi organism reproductive process GO:0044703 36 0.024
positive regulation of lipid metabolic process GO:0045834 1 0.024
response to external stimulus GO:0009605 264 0.024
negative regulation of biosynthetic process GO:0009890 55 0.024
negative regulation of gene expression GO:0010629 65 0.024
translational initiation GO:0006413 3 0.024
positive regulation of cell cycle GO:0045787 3 0.024
positive regulation of cellular protein metabolic process GO:0032270 22 0.024
formation of primary germ layer GO:0001704 62 0.023
regulation of immune system process GO:0002682 34 0.023
multi organism process GO:0051704 134 0.023
development of primary female sexual characteristics GO:0046545 4 0.023
camera type eye morphogenesis GO:0048593 108 0.023
retina development in camera type eye GO:0060041 146 0.023
regulation of bmp signaling pathway GO:0030510 39 0.022
response to vitamin GO:0033273 3 0.022
locomotion GO:0040011 313 0.022
negative regulation of nucleic acid templated transcription GO:1903507 45 0.022
digestive system development GO:0055123 289 0.022
lymphocyte proliferation GO:0046651 1 0.021
regulation of catalytic activity GO:0050790 55 0.021
endoderm formation GO:0001706 29 0.021
exocytosis GO:0006887 1 0.021
cell morphogenesis involved in differentiation GO:0000904 195 0.021
response to oxygen containing compound GO:1901700 55 0.021
growth GO:0040007 174 0.020
regulation of inflammatory response GO:0050727 2 0.020
regulation of phosphorus metabolic process GO:0051174 43 0.020
phosphate containing compound metabolic process GO:0006796 108 0.020
positive regulation of cell activation GO:0050867 1 0.020
regulation of endodermal cell differentiation GO:1903224 15 0.020
negative regulation of cellular metabolic process GO:0031324 77 0.020
reproduction GO:0000003 40 0.020
positive regulation of translation GO:0045727 1 0.020
response to organic substance GO:0010033 153 0.019
endothelial cell differentiation GO:0045446 20 0.019
positive regulation of metabolic process GO:0009893 108 0.019
neuron development GO:0048666 262 0.019
programmed cell death GO:0012501 119 0.019
developmental growth GO:0048589 166 0.019
cell migration GO:0016477 237 0.018
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.018
negative regulation of metabolic process GO:0009892 86 0.018
regulation of skeletal muscle tissue development GO:0048641 4 0.018
single organism metabolic process GO:0044710 217 0.018
mitotic cell cycle embryonic GO:0045448 2 0.018
death GO:0016265 121 0.018
endodermal cell differentiation GO:0035987 19 0.018
protein phosphorylation GO:0006468 47 0.018
phosphatidylinositol mediated signaling GO:0048015 2 0.018
stem cell maintenance GO:0019827 4 0.017
female meiotic division GO:0007143 2 0.017
regulation of circadian rhythm GO:0042752 4 0.017
positive regulation of protein polymerization GO:0032273 2 0.017
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.017
negative regulation of macromolecule metabolic process GO:0010605 76 0.016
regulation of apoptotic process GO:0042981 98 0.016
endoderm development GO:0007492 49 0.016
amine metabolic process GO:0009308 2 0.016
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.016
regulation of gastrulation GO:0010470 24 0.016
regulation of phosphate metabolic process GO:0019220 43 0.016
stem cell development GO:0048864 82 0.015
establishment of localization in cell GO:0051649 77 0.015
leukocyte proliferation GO:0070661 1 0.015
regulation of mrna processing GO:0050684 3 0.015
regulation of binding GO:0051098 3 0.015
muscle tissue development GO:0060537 110 0.015
regulation of biological quality GO:0065008 263 0.015
positive regulation of immune system process GO:0002684 17 0.015
cell surface receptor signaling pathway involved in heart development GO:0061311 20 0.015
regulation of multicellular organismal development GO:2000026 223 0.015
cellular response to chemical stimulus GO:0070887 157 0.015
regulation of embryonic development GO:0045995 47 0.014
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.014
phosphorus metabolic process GO:0006793 109 0.014
regulation of ph GO:0006885 3 0.014
b cell mediated immunity GO:0019724 3 0.014
cytokinesis GO:0000910 3 0.014
regulation of ion transmembrane transporter activity GO:0032412 2 0.014
regulation of protein complex assembly GO:0043254 3 0.014
negative regulation of signal transduction GO:0009968 94 0.014
internal protein amino acid acetylation GO:0006475 2 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.014
regulation of cellular biosynthetic process GO:0031326 245 0.014
generation of neurons GO:0048699 385 0.014
response to vitamin b3 GO:0033552 2 0.014
cell fate specification GO:0001708 68 0.014
negative regulation of cytokine production GO:0001818 1 0.013
negative regulation of signaling GO:0023057 96 0.013
carboxylic acid metabolic process GO:0019752 22 0.013
cell death GO:0008219 121 0.013
negative regulation of multi organism process GO:0043901 3 0.013
cellular protein modification process GO:0006464 100 0.013
response to wounding GO:0009611 116 0.013
positive regulation of immune response GO:0050778 11 0.013
negative regulation of apoptotic process GO:0043066 55 0.013
embryonic hemopoiesis GO:0035162 53 0.013
monovalent inorganic cation transport GO:0015672 42 0.013
single organism reproductive process GO:0044702 40 0.013
peptide transport GO:0015833 1 0.013
spindle assembly GO:0051225 2 0.013
organelle assembly GO:0070925 110 0.013
regionalization GO:0003002 274 0.013
response to stress GO:0006950 263 0.012
cellular amine metabolic process GO:0044106 2 0.012
regulation of cell fate commitment GO:0010453 22 0.012
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.012
embryonic digestive tract development GO:0048566 4 0.012
regulation of multicellular organism growth GO:0040014 4 0.012
negative regulation of fertilization GO:0060467 1 0.012
cellular lipid metabolic process GO:0044255 36 0.012
response to abiotic stimulus GO:0009628 122 0.012
single organism biosynthetic process GO:0044711 71 0.012
germ cell development GO:0007281 22 0.012
negative regulation of programmed cell death GO:0043069 58 0.012
negative regulation of rna metabolic process GO:0051253 48 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.012
positive regulation of molecular function GO:0044093 33 0.012
positive regulation of cellular biosynthetic process GO:0031328 68 0.012
microtubule polymerization GO:0046785 2 0.012
phosphorylation GO:0016310 69 0.012
hindbrain development GO:0030902 91 0.012
spermatid differentiation GO:0048515 2 0.012
cell proliferation GO:0008283 80 0.012
astrocyte differentiation GO:0048708 1 0.011
immunoglobulin mediated immune response GO:0016064 3 0.011
regulation of cellular amine metabolic process GO:0033238 0 0.011
mononuclear cell proliferation GO:0032943 1 0.011
ovulation cycle process GO:0022602 2 0.011
skeletal system development GO:0001501 181 0.011
mitochondrion organization GO:0007005 4 0.011
ear development GO:0043583 127 0.011
regulation of skeletal muscle fiber development GO:0048742 2 0.011
regulation of tube size GO:0035150 2 0.011
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.011
bmp signaling pathway GO:0030509 52 0.011
negative regulation of rna biosynthetic process GO:1902679 45 0.011
positive regulation of developmental process GO:0051094 50 0.011
cell surface receptor signaling pathway GO:0007166 325 0.011
skeletal muscle tissue development GO:0007519 67 0.011
regulation of cellular localization GO:0060341 12 0.011
regulation of oocyte development GO:0060281 3 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.010
mesoderm development GO:0007498 88 0.010
organonitrogen compound metabolic process GO:1901564 74 0.010
cell fate commitment GO:0045165 99 0.010
regulation of protein phosphorylation GO:0001932 18 0.010
isoprenoid metabolic process GO:0006720 15 0.010
positive regulation of cytokine production GO:0001819 2 0.010

zp2.2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
bone disease DOID:0080001 0 0.035
disease of anatomical entity DOID:7 0 0.035
musculoskeletal system disease DOID:17 0 0.035
connective tissue disease DOID:65 0 0.035
nervous system disease DOID:863 0 0.011