Danio rerio

0 known processes

thoc6

THO complex 6 homolog (Drosophila)

(Aliases: MGC174338,MGC101618,zgc:101618)

thoc6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.285
cellular nitrogen compound metabolic process GO:0034641 290 0.206
organic substance biosynthetic process GO:1901576 289 0.106
heterocycle metabolic process GO:0046483 290 0.106
organelle organization GO:0006996 227 0.090
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.083
nucleic acid metabolic process GO:0090304 244 0.083
modification dependent macromolecule catabolic process GO:0043632 3 0.082
nuclear import GO:0051170 3 0.081
establishment of protein localization to organelle GO:0072594 4 0.081
maintenance of location GO:0051235 4 0.080
nitrogen compound metabolic process GO:0006807 319 0.080
organic cyclic compound biosynthetic process GO:1901362 223 0.079
locomotion GO:0040011 313 0.077
regulation of nitrogen compound metabolic process GO:0051171 251 0.070
rna metabolic process GO:0016070 219 0.065
nucleobase containing compound metabolic process GO:0006139 274 0.065
gene expression GO:0010467 252 0.062
Human
organic cyclic compound metabolic process GO:1901360 301 0.059
regulation of protein import into nucleus GO:0042306 2 0.059
protein import GO:0017038 3 0.059
regulation of metabolic process GO:0019222 359 0.056
neuron differentiation GO:0030182 353 0.055
cellular biosynthetic process GO:0044249 286 0.051
regulation of primary metabolic process GO:0080090 311 0.050
embryo development ending in birth or egg hatching GO:0009792 271 0.050
cellular macromolecule metabolic process GO:0044260 391 0.049
generation of neurons GO:0048699 385 0.049
aromatic compound biosynthetic process GO:0019438 217 0.048
rna biosynthetic process GO:0032774 181 0.047
protein import into nucleus GO:0006606 3 0.044
single organism metabolic process GO:0044710 217 0.044
regulation of nucleocytoplasmic transport GO:0046822 2 0.042
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.042
response to chemical GO:0042221 320 0.042
regulation of protein localization to nucleus GO:1900180 2 0.041
regulation of protein ubiquitination GO:0031396 3 0.041
regulation of intracellular protein transport GO:0033157 3 0.040
regulation of macromolecule biosynthetic process GO:0010556 225 0.040
regulation of rna metabolic process GO:0051252 224 0.039
cellular protein modification process GO:0006464 100 0.037
cellular nitrogen compound biosynthetic process GO:0044271 218 0.036
positive regulation of transport GO:0051050 2 0.035
establishment of localization GO:0051234 244 0.035
Human
biosynthetic process GO:0009058 294 0.035
regulation of cellular metabolic process GO:0031323 320 0.035
positive regulation of cell cycle GO:0045787 3 0.034
axon development GO:0061564 166 0.034
cognition GO:0050890 1 0.034
cellular protein catabolic process GO:0044257 4 0.034
protein localization to nucleus GO:0034504 3 0.033
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.033
regulation of cytoplasmic transport GO:1903649 4 0.033
mitotic dna integrity checkpoint GO:0044774 4 0.032
cellular protein metabolic process GO:0044267 129 0.032
macromolecular complex assembly GO:0065003 35 0.031
regulation of transcription dna templated GO:0006355 213 0.031
cell projection organization GO:0030030 284 0.030
negative regulation of cellular process GO:0048523 283 0.030
Human
cell morphogenesis GO:0000902 289 0.030
protein targeting to nucleus GO:0044744 3 0.030
positive regulation of cellular catabolic process GO:0031331 3 0.029
regulation of macromolecule metabolic process GO:0060255 317 0.029
macromolecule biosynthetic process GO:0009059 227 0.029
positive regulation of cellular process GO:0048522 201 0.029
cellular component morphogenesis GO:0032989 336 0.029
neuron development GO:0048666 262 0.029
organonitrogen compound metabolic process GO:1901564 74 0.029
single organism nuclear import GO:1902593 3 0.029
regulation of rna biosynthetic process GO:2001141 213 0.028
positive regulation of biological process GO:0048518 253 0.028
carbohydrate derivative metabolic process GO:1901135 61 0.027
transcription dna templated GO:0006351 181 0.027
regulation of gene expression GO:0010468 265 0.027
modification dependent protein catabolic process GO:0019941 3 0.027
regulation of protein targeting GO:1903533 2 0.027
nucleocytoplasmic transport GO:0006913 4 0.027
Human
cell part morphogenesis GO:0032990 246 0.027
cellular response to organic cyclic compound GO:0071407 38 0.027
positive regulation of histone modification GO:0031058 1 0.027
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.026
nucleobase containing compound biosynthetic process GO:0034654 205 0.026
ubiquitin dependent protein catabolic process GO:0006511 3 0.026
positive regulation of chromatin modification GO:1903310 1 0.026
lipid storage GO:0019915 1 0.025
spliceosomal snrnp assembly GO:0000387 2 0.025
nucleic acid templated transcription GO:0097659 181 0.025
cell morphogenesis involved in differentiation GO:0000904 195 0.024
protein acylation GO:0043543 3 0.024
neuron projection development GO:0031175 180 0.024
rna splicing GO:0008380 16 0.023
positive regulation of cellular amine metabolic process GO:0033240 0 0.023
organic acid metabolic process GO:0006082 31 0.023
regulation of cellular protein catabolic process GO:1903362 1 0.023
regulation of biological quality GO:0065008 263 0.023
negative regulation of protein transport GO:0051224 3 0.023
macromolecule modification GO:0043412 111 0.022
regulation of protein catabolic process GO:0042176 1 0.022
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.022
regulation of establishment of protein localization GO:0070201 4 0.021
regulation of cellular biosynthetic process GO:0031326 245 0.021
meiotic chromosome segregation GO:0045132 3 0.021
transcription from rna polymerase ii promoter GO:0006366 80 0.021
positive regulation of catabolic process GO:0009896 4 0.021
neuron projection morphogenesis GO:0048812 161 0.021
meiotic nuclear division GO:0007126 4 0.021
regulation of cellular amino acid metabolic process GO:0006521 0 0.020
regulation of histone methylation GO:0031060 3 0.020
cell cycle GO:0007049 93 0.020
cellular amine metabolic process GO:0044106 2 0.020
negative regulation of biological process GO:0048519 304 0.020
Human
growth GO:0040007 174 0.020
amine metabolic process GO:0009308 2 0.020
protein metabolic process GO:0019538 183 0.019
positive regulation of chromosome organization GO:2001252 1 0.019
axonogenesis GO:0007409 152 0.019
cellular aromatic compound metabolic process GO:0006725 295 0.019
negative regulation of intracellular transport GO:0032387 3 0.019
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.018
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.018
response to stress GO:0006950 263 0.018
Fly
multi organism process GO:0051704 134 0.018
Human
negative regulation of cytoplasmic transport GO:1903650 2 0.018
cellular component biogenesis GO:0044085 178 0.018
specification of axis polarity GO:0065001 4 0.018
aging GO:0007568 2 0.018
positive regulation of metabolic process GO:0009893 108 0.017
single organism organelle organization GO:1902589 199 0.017
proteasomal protein catabolic process GO:0010498 2 0.017
negative regulation of protein localization to nucleus GO:1900181 2 0.017
organelle assembly GO:0070925 110 0.017
regulation of nucleic acid templated transcription GO:1903506 213 0.017
ribonucleoside monophosphate catabolic process GO:0009158 4 0.017
cell projection morphogenesis GO:0048858 244 0.016
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.016
system process GO:0003008 185 0.016
peptidyl lysine acetylation GO:0018394 2 0.015
regulation of protein complex assembly GO:0043254 3 0.015
heterocycle biosynthetic process GO:0018130 215 0.015
cellular amino acid metabolic process GO:0006520 7 0.015
response to organic substance GO:0010033 153 0.015
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.015
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.015
blood vessel development GO:0001568 246 0.014
organism emergence from protective structure GO:0071684 4 0.014
stem cell maintenance GO:0019827 4 0.014
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.014
negative regulation of intracellular protein transport GO:0090317 3 0.014
rrna catabolic process GO:0016075 1 0.014
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.014
mitochondrion organization GO:0007005 4 0.014
regulation of cell communication GO:0010646 232 0.014
carboxylic acid metabolic process GO:0019752 22 0.014
neurological system process GO:0050877 62 0.014
mitotic g2 dna damage checkpoint GO:0007095 3 0.013
muscle structure development GO:0061061 196 0.013
regulation of cellular amine metabolic process GO:0033238 0 0.013
chromosome organization involved in meiosis GO:0070192 1 0.013
purine nucleoside monophosphate catabolic process GO:0009128 4 0.013
regulation of meiotic cell cycle GO:0051445 1 0.013
chromatin organization GO:0006325 22 0.013
adult behavior GO:0030534 2 0.013
interspecies interaction between organisms GO:0044419 4 0.013
Human
rna localization GO:0006403 4 0.013
Human
regulation of mitochondrion organization GO:0010821 1 0.013
negative regulation of protein import into nucleus GO:0042308 2 0.013
programmed cell death GO:0012501 119 0.013
Human
regulation of transporter activity GO:0032409 2 0.012
mrna splicing via spliceosome GO:0000398 10 0.012
cellular ketone metabolic process GO:0042180 11 0.012
apoptotic process GO:0006915 116 0.012
Human
sensory organ morphogenesis GO:0090596 200 0.012
nuclear transport GO:0051169 4 0.012
Human
i kappab kinase nf kappab signaling GO:0007249 4 0.012
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 10 0.012
positive regulation of cytokine production GO:0001819 2 0.012
nucleoside monophosphate catabolic process GO:0009125 4 0.012
nucleoside phosphate metabolic process GO:0006753 28 0.012
mrna metabolic process GO:0016071 20 0.012
regulation of cellular protein metabolic process GO:0032268 52 0.012
macromolecular complex subunit organization GO:0043933 74 0.012
g2 m transition of mitotic cell cycle GO:0000086 4 0.012
small molecule metabolic process GO:0044281 77 0.012
cellular macromolecule biosynthetic process GO:0034645 224 0.012
regulation of cell cycle GO:0051726 52 0.012
multicellular organism growth GO:0035264 4 0.011
behavior GO:0007610 74 0.011
regulation of binding GO:0051098 3 0.011
single organism reproductive process GO:0044702 40 0.011
developmental growth GO:0048589 166 0.011
response to organic cyclic compound GO:0014070 51 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
regulation of cellular component organization GO:0051128 86 0.011
cell death GO:0008219 121 0.011
Human
nucleobase containing small molecule metabolic process GO:0055086 32 0.011
anterior posterior pattern specification GO:0009952 152 0.011
positive regulation of cellular metabolic process GO:0031325 94 0.011
positive regulation of dna metabolic process GO:0051054 1 0.011
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.011
Human
mitotic cell cycle process GO:1903047 48 0.011
catabolic process GO:0009056 32 0.011
oxoacid metabolic process GO:0043436 31 0.010
meiosis ii GO:0007135 1 0.010
cellular response to biotic stimulus GO:0071216 3 0.010
peptide transport GO:0015833 1 0.010
regulation of heart growth GO:0060420 2 0.010
cellular component assembly GO:0022607 170 0.010
lipid homeostasis GO:0055088 3 0.010
nucleobase containing compound transport GO:0015931 2 0.010
Human
regulation of developmental process GO:0050793 247 0.010
vasculature development GO:0001944 278 0.010
positive regulation of immune effector process GO:0002699 3 0.010
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.010

thoc6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.019
inherited metabolic disorder DOID:655 0 0.019
disease of anatomical entity DOID:7 0 0.011