Danio rerio

52 known processes

pbx2

pre-B-cell leukemia transcription factor 2

(Aliases: wu:fb73g03,pbxy)

pbx2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of metabolic process GO:0019222 359 0.219
Zebrafish Mouse Fly
signal transduction GO:0007165 455 0.203
single organism localization GO:1902578 225 0.168
Fly
positive regulation of transport GO:0051050 2 0.136
modification dependent macromolecule catabolic process GO:0043632 3 0.126
cellular macromolecule metabolic process GO:0044260 391 0.118
Zebrafish Mouse Fly
cellular nitrogen compound metabolic process GO:0034641 290 0.106
Zebrafish Mouse Fly
larval development GO:0002164 2 0.106
ubiquitin dependent protein catabolic process GO:0006511 3 0.103
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.098
regulation of cellular metabolic process GO:0031323 320 0.098
Zebrafish Mouse Fly
maintenance of location GO:0051235 4 0.097
regulation of macromolecule metabolic process GO:0060255 317 0.089
Zebrafish Mouse Fly
modification dependent protein catabolic process GO:0019941 3 0.088
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.085
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.085
cell surface receptor signaling pathway GO:0007166 325 0.084
nitrogen compound metabolic process GO:0006807 319 0.081
Zebrafish Mouse Fly
organelle organization GO:0006996 227 0.079
positive regulation of cellular component biogenesis GO:0044089 3 0.077
regulation of cellular biosynthetic process GO:0031326 245 0.077
Zebrafish Mouse Fly
small molecule metabolic process GO:0044281 77 0.076
protein localization to nucleus GO:0034504 3 0.073
Fly
single organism transport GO:0044765 206 0.073
Fly
regulation of primary metabolic process GO:0080090 311 0.072
Zebrafish Mouse Fly
embryo development ending in birth or egg hatching GO:0009792 271 0.071
Zebrafish
lipid storage GO:0019915 1 0.068
regulation of multicellular organismal process GO:0051239 277 0.063
cell substrate adhesion GO:0031589 4 0.060
blood vessel development GO:0001568 246 0.058
cellular aromatic compound metabolic process GO:0006725 295 0.058
Zebrafish Mouse Fly
positive regulation of secretion by cell GO:1903532 1 0.058
nucleic acid metabolic process GO:0090304 244 0.055
Zebrafish Mouse Fly
carboxylic acid metabolic process GO:0019752 22 0.055
proteasomal protein catabolic process GO:0010498 2 0.055
negative regulation of biological process GO:0048519 304 0.054
regulation of signal transduction GO:0009966 225 0.054
actin filament based movement GO:0030048 1 0.054
heterocycle biosynthetic process GO:0018130 215 0.053
Zebrafish Mouse Fly
regulation of protein ubiquitination GO:0031396 3 0.051
cellular protein catabolic process GO:0044257 4 0.051
cellular response to external stimulus GO:0071496 2 0.051
aging GO:0007568 2 0.051
regulation of protein catabolic process GO:0042176 1 0.051
regulation of nitrogen compound metabolic process GO:0051171 251 0.050
Zebrafish Mouse Fly
protein localization to plasma membrane GO:0072659 1 0.049
organic cyclic compound metabolic process GO:1901360 301 0.048
Zebrafish Mouse Fly
cell projection organization GO:0030030 284 0.047
Zebrafish
neuron differentiation GO:0030182 353 0.047
Zebrafish
regulation of wound healing GO:0061041 2 0.046
regulation of nucleic acid templated transcription GO:1903506 213 0.045
Zebrafish Mouse Fly
cellular response to xenobiotic stimulus GO:0071466 35 0.045
cellular component morphogenesis GO:0032989 336 0.045
Zebrafish
nucleobase containing compound metabolic process GO:0006139 274 0.045
Zebrafish Mouse Fly
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.043
Zebrafish Mouse Fly
exocytosis GO:0006887 1 0.043
biosynthetic process GO:0009058 294 0.041
Zebrafish Mouse Fly
rna metabolic process GO:0016070 219 0.041
Zebrafish Mouse Fly
cellular response to nutrient levels GO:0031669 2 0.041
regulation of gene expression GO:0010468 265 0.040
Zebrafish Mouse Fly
positive regulation of catabolic process GO:0009896 4 0.040
positive regulation of biological process GO:0048518 253 0.040
Zebrafish Mouse Fly
regulation of macromolecule biosynthetic process GO:0010556 225 0.040
Zebrafish Mouse Fly
regulation of cellular ketone metabolic process GO:0010565 7 0.039
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.039
nucleobase containing compound biosynthetic process GO:0034654 205 0.039
Zebrafish Mouse Fly
inorganic cation transmembrane transport GO:0098662 50 0.038
cellular response to endogenous stimulus GO:0071495 68 0.038
positive regulation of secretion GO:0051047 1 0.038
regulation of reproductive process GO:2000241 4 0.038
regulation of cell communication GO:0010646 232 0.038
single organism metabolic process GO:0044710 217 0.037
cytoplasm organization GO:0007028 4 0.037
positive regulation of nucleoside metabolic process GO:0045979 1 0.037
nucleoside monophosphate catabolic process GO:0009125 4 0.037
cellular response to chemical stimulus GO:0070887 157 0.037
positive regulation of cellular catabolic process GO:0031331 3 0.036
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.036
Zebrafish Mouse Fly
aromatic compound biosynthetic process GO:0019438 217 0.036
Zebrafish Mouse Fly
cellular response to starvation GO:0009267 1 0.036
neurotransmitter secretion GO:0007269 2 0.036
neuron neuron synaptic transmission GO:0007270 1 0.036
response to stress GO:0006950 263 0.035
stem cell proliferation GO:0072089 4 0.035
regulation of purine nucleotide catabolic process GO:0033121 2 0.035
oocyte anterior posterior axis specification GO:0007314 4 0.035
actin mediated cell contraction GO:0070252 1 0.035
ion transport GO:0006811 114 0.035
negative regulation of protein phosphorylation GO:0001933 4 0.035
regulation of binding GO:0051098 3 0.035
generation of neurons GO:0048699 385 0.035
Zebrafish
ion transmembrane transport GO:0034220 91 0.035
positive regulation of protein complex assembly GO:0031334 2 0.034
enzyme linked receptor protein signaling pathway GO:0007167 106 0.034
neurotransmitter transport GO:0006836 2 0.034
ribonucleoside monophosphate catabolic process GO:0009158 4 0.033
phagocytosis GO:0006909 3 0.033
gtp metabolic process GO:0046039 4 0.033
nucleic acid templated transcription GO:0097659 181 0.033
Zebrafish Mouse Fly
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.033
cellular ketone metabolic process GO:0042180 11 0.033
organic substance biosynthetic process GO:1901576 289 0.033
Zebrafish Mouse Fly
cognition GO:0050890 1 0.033
cellular response to extracellular stimulus GO:0031668 2 0.032
cellular component movement GO:0006928 335 0.032
Zebrafish
regulation of cell shape GO:0008360 1 0.032
regulation of autophagy GO:0010506 3 0.032
regulation of nucleotide catabolic process GO:0030811 2 0.032
atp catabolic process GO:0006200 4 0.031
morphogenesis of an epithelium GO:0002009 333 0.031
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.031
cellular amine metabolic process GO:0044106 2 0.031
regulation of hormone secretion GO:0046883 2 0.031
guanosine containing compound catabolic process GO:1901069 2 0.031
cellular carbohydrate metabolic process GO:0044262 4 0.031
cell morphogenesis GO:0000902 289 0.031
Zebrafish
synaptic growth at neuromuscular junction GO:0051124 2 0.030
organic acid metabolic process GO:0006082 31 0.030
regulation of cellular amino acid metabolic process GO:0006521 0 0.030
locomotion GO:0040011 313 0.030
Zebrafish
vacuolar transport GO:0007034 2 0.030
regulation of biosynthetic process GO:0009889 250 0.029
Zebrafish Mouse Fly
amine metabolic process GO:0009308 2 0.029
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.029
negative regulation of catabolic process GO:0009895 3 0.029
gtp catabolic process GO:0006184 2 0.029
transport GO:0006810 220 0.028
Fly
protein polyubiquitination GO:0000209 4 0.028
cytoskeleton dependent cytokinesis GO:0061640 3 0.028
organonitrogen compound metabolic process GO:1901564 74 0.028
transcription dna templated GO:0006351 181 0.028
Zebrafish Mouse Fly
keratinocyte differentiation GO:0030216 0 0.028
hormone secretion GO:0046879 2 0.028
regulation of biological quality GO:0065008 263 0.028
cellular nitrogen compound biosynthetic process GO:0044271 218 0.028
Zebrafish Mouse Fly
protein localization GO:0008104 40 0.028
Fly
cation transport GO:0006812 81 0.027
macromolecule biosynthetic process GO:0009059 227 0.027
Zebrafish Mouse Fly
macromolecular complex subunit organization GO:0043933 74 0.027
nuclear transport GO:0051169 4 0.027
Fly
regulation of mrna processing GO:0050684 3 0.027
secondary metabolic process GO:0019748 3 0.027
protein modification process GO:0036211 100 0.027
cellular macromolecular complex assembly GO:0034622 24 0.027
regulation of response to stimulus GO:0048583 269 0.027
system process GO:0003008 185 0.027
meiotic nuclear division GO:0007126 4 0.027
cellular biosynthetic process GO:0044249 286 0.026
Zebrafish Mouse Fly
hormone transport GO:0009914 2 0.026
heterocycle metabolic process GO:0046483 290 0.026
Zebrafish Mouse Fly
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.026
Zebrafish
regulation of developmental process GO:0050793 247 0.026
Fly
positive regulation of cell cycle GO:0045787 3 0.026
carbohydrate biosynthetic process GO:0016051 1 0.026
regulation of cellular amine metabolic process GO:0033238 0 0.026
regulation of signaling GO:0023051 235 0.026
regulation of meiotic cell cycle GO:0051445 1 0.026
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.026
Zebrafish Mouse Fly
autophagy GO:0006914 4 0.026
regulation of mrna splicing via spliceosome GO:0048024 3 0.026
regulation of ion transmembrane transporter activity GO:0032412 2 0.026
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.026
specification of axis polarity GO:0065001 4 0.026
regulation of protein complex assembly GO:0043254 3 0.025
macromolecule localization GO:0033036 54 0.025
Fly
protein metabolic process GO:0019538 183 0.025
response to hexose GO:0009746 3 0.025
carbohydrate derivative metabolic process GO:1901135 61 0.025
regulation of nucleoside metabolic process GO:0009118 2 0.025
establishment of localization in cell GO:0051649 77 0.025
Fly
regulation of protein transport GO:0051223 3 0.025
triglyceride homeostasis GO:0070328 2 0.025
alternative mrna splicing via spliceosome GO:0000380 1 0.024
gene expression GO:0010467 252 0.024
Zebrafish Mouse Fly
negative regulation of cytoplasmic transport GO:1903650 2 0.024
cell motility GO:0048870 244 0.024
Zebrafish
heart development GO:0007507 313 0.024
stem cell maintenance GO:0019827 4 0.024
extrinsic apoptotic signaling pathway GO:0097191 3 0.024
purine nucleoside monophosphate catabolic process GO:0009128 4 0.024
pole plasm assembly GO:0007315 4 0.024
regulation of transcription dna templated GO:0006355 213 0.024
Zebrafish Mouse Fly
digestive tract morphogenesis GO:0048546 231 0.023
neuron projection morphogenesis GO:0048812 161 0.023
Zebrafish
ameboidal type cell migration GO:0001667 143 0.023
Zebrafish
rna localization GO:0006403 4 0.023
lipid catabolic process GO:0016042 4 0.023
establishment of localization GO:0051234 244 0.023
Fly
oxoacid metabolic process GO:0043436 31 0.023
response to xenobiotic stimulus GO:0009410 45 0.022
nuclear migration GO:0007097 3 0.022
organic cyclic compound biosynthetic process GO:1901362 223 0.022
Zebrafish Mouse Fly
regulation of circadian rhythm GO:0042752 4 0.022
protein targeting to nucleus GO:0044744 3 0.022
Fly
macromolecular complex assembly GO:0065003 35 0.022
cellular response to organic substance GO:0071310 105 0.022
regulation of epidermis development GO:0045682 2 0.022
organic acid catabolic process GO:0016054 3 0.022
response to abiotic stimulus GO:0009628 122 0.022
cellular amino acid metabolic process GO:0006520 7 0.022
protein import into nucleus GO:0006606 3 0.022
Fly
epithelial tube morphogenesis GO:0060562 148 0.021
regulation of metal ion transport GO:0010959 4 0.021
protein k48 linked ubiquitination GO:0070936 1 0.021
regulation of establishment of protein localization GO:0070201 4 0.021
small gtpase mediated signal transduction GO:0007264 8 0.021
regulation of synapse assembly GO:0051963 3 0.021
negative regulation of rna splicing GO:0033119 1 0.021
regulation of transmembrane transporter activity GO:0022898 2 0.021
cellular protein modification process GO:0006464 100 0.021
tube morphogenesis GO:0035239 349 0.021
regulation of system process GO:0044057 40 0.021
peptide transport GO:0015833 1 0.021
peptidyl lysine acetylation GO:0018394 2 0.021
negative regulation of metabolic process GO:0009892 86 0.020
growth GO:0040007 174 0.020
multi organism process GO:0051704 134 0.020
embryonic organ morphogenesis GO:0048562 274 0.020
Zebrafish
regulation of anatomical structure morphogenesis GO:0022603 130 0.020
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.020
phosphate containing compound metabolic process GO:0006796 108 0.020
cellular component disassembly GO:0022411 1 0.020
cell cycle arrest GO:0007050 1 0.020
regulation of cellular protein catabolic process GO:1903362 1 0.020
regulation of localization GO:0032879 104 0.020
response to chemical GO:0042221 320 0.020
Zebrafish
cellular response to decreased oxygen levels GO:0036294 1 0.020
cellular macromolecule biosynthetic process GO:0034645 224 0.020
Zebrafish Mouse Fly
intracellular mrna localization GO:0008298 1 0.019
cellular component assembly GO:0022607 170 0.019
negative regulation of signaling GO:0023057 96 0.019
regulation of transporter activity GO:0032409 2 0.019
cellular protein metabolic process GO:0044267 129 0.019
negative regulation of intracellular protein transport GO:0090317 3 0.019
camera type eye development GO:0043010 222 0.019
endosomal transport GO:0016197 2 0.019
regulation of dendrite development GO:0050773 3 0.019
regulation of reactive oxygen species metabolic process GO:2000377 2 0.019
synaptic vesicle transport GO:0048489 1 0.019
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.019
cellular response to hypoxia GO:0071456 1 0.019
gastrulation GO:0007369 208 0.019
epidermis development GO:0008544 48 0.019
acylglycerol homeostasis GO:0055090 2 0.019
intracellular signal transduction GO:0035556 85 0.019
cytokinesis GO:0000910 3 0.018
regulation of cell development GO:0060284 100 0.018
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.018
response to glucose GO:0009749 3 0.018
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.018
localization of cell GO:0051674 244 0.018
Zebrafish
macromolecule modification GO:0043412 111 0.018
sleep GO:0030431 1 0.018
cell migration GO:0016477 237 0.018
Zebrafish
lipid homeostasis GO:0055088 3 0.018
establishment of synaptic vesicle localization GO:0097480 1 0.018
response to carbohydrate GO:0009743 3 0.018
negative regulation of cellular metabolic process GO:0031324 77 0.017
single organism cellular localization GO:1902580 46 0.017
Fly
regulation of rna biosynthetic process GO:2001141 213 0.017
Zebrafish Mouse Fly
regulation of carbohydrate metabolic process GO:0006109 4 0.017
leukocyte mediated cytotoxicity GO:0001909 1 0.017
inorganic ion transmembrane transport GO:0098660 57 0.017
regulation of transport GO:0051049 45 0.017
cellular lipid catabolic process GO:0044242 3 0.017
negative regulation of protein complex assembly GO:0031333 1 0.017
regulation of synapse organization GO:0050807 3 0.017
cell morphogenesis involved in differentiation GO:0000904 195 0.017
Zebrafish
establishment of protein localization to organelle GO:0072594 4 0.017
Fly
negative regulation of response to stimulus GO:0048585 104 0.017
regulation of oocyte development GO:0060281 3 0.017
negative regulation of kinase activity GO:0033673 4 0.017
protein complex subunit organization GO:0071822 46 0.017
regulation of cytoplasmic transport GO:1903649 4 0.017
single organism membrane fusion GO:0044801 2 0.017
diterpenoid metabolic process GO:0016101 15 0.017
multicellular organism growth GO:0035264 4 0.017
amino acid transport GO:0006865 2 0.017
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.017
cellular response to oxygen levels GO:0071453 1 0.017
response to organic substance GO:0010033 153 0.017
negative regulation of protein transport GO:0051224 3 0.016
death GO:0016265 121 0.016
regionalization GO:0003002 274 0.016
Mouse
negative regulation of intracellular transport GO:0032387 3 0.016
regulation of microtubule cytoskeleton organization GO:0070507 3 0.016
fatty acid oxidation GO:0019395 1 0.016
organelle fusion GO:0048284 3 0.016
guanosine containing compound metabolic process GO:1901068 4 0.016
small molecule catabolic process GO:0044282 3 0.016
adult behavior GO:0030534 2 0.016
programmed cell death GO:0012501 119 0.016
regulation of multicellular organismal development GO:2000026 223 0.016
nuclear import GO:0051170 3 0.016
Fly
negative regulation of cell communication GO:0010648 96 0.016
regulation of cell death GO:0010941 103 0.016
positive regulation of nucleotide catabolic process GO:0030813 1 0.016
nuclear export GO:0051168 1 0.015
protein sumoylation GO:0016925 2 0.015
double strand break repair GO:0006302 3 0.015
regulation of dendrite morphogenesis GO:0048814 3 0.015
cellular catabolic process GO:0044248 27 0.015
microtubule organizing center organization GO:0031023 1 0.015
regulation of neurotransmitter secretion GO:0046928 1 0.015
cell part morphogenesis GO:0032990 246 0.015
Zebrafish
melanin metabolic process GO:0006582 2 0.015
wound healing GO:0042060 90 0.015
neuroblast proliferation GO:0007405 2 0.015
negative regulation of macromolecule metabolic process GO:0010605 76 0.015
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.015
nuclear envelope organization GO:0006998 2 0.015
positive regulation of apoptotic signaling pathway GO:2001235 1 0.015
protein stabilization GO:0050821 2 0.014
oxidation reduction process GO:0055114 41 0.014
cell cycle GO:0007049 93 0.014
anterior posterior pattern specification GO:0009952 152 0.014
regulation of calcium ion transport GO:0051924 2 0.014
positive regulation of dna metabolic process GO:0051054 1 0.014
apoptotic process GO:0006915 116 0.014
single organism nuclear import GO:1902593 3 0.014
Fly
negative regulation of cellular process GO:0048523 283 0.014
nucleocytoplasmic transport GO:0006913 4 0.014
Fly
developmental growth involved in morphogenesis GO:0060560 86 0.014
response to monosaccharide GO:0034284 3 0.014
regulation of stem cell differentiation GO:2000736 4 0.014
transcription from rna polymerase ii promoter GO:0006366 80 0.014
Zebrafish Mouse Fly
golgi vesicle transport GO:0048193 3 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.014
neuron development GO:0048666 262 0.014
Zebrafish
cation transmembrane transport GO:0098655 65 0.014
regulation of exocytosis GO:0017157 1 0.014
positive regulation of gtp catabolic process GO:0033126 1 0.014
cell proliferation GO:0008283 80 0.014
glial cell migration GO:0008347 3 0.014
regulation of programmed cell death GO:0043067 101 0.014
production of molecular mediator of immune response GO:0002440 2 0.014
sequestering of metal ion GO:0051238 3 0.014
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.014
negative regulation of signal transduction GO:0009968 94 0.014
meiotic cell cycle process GO:1903046 3 0.014
wnt signaling pathway planar cell polarity pathway GO:0060071 4 0.014
positive regulation of reproductive process GO:2000243 2 0.014
negative regulation of defense response GO:0031348 2 0.014
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.014
carbohydrate homeostasis GO:0033500 1 0.014
eye development GO:0001654 277 0.014
embryonic organ development GO:0048568 381 0.013
Zebrafish
multicellular organismal reproductive process GO:0048609 35 0.013
positive regulation of wound healing GO:0090303 1 0.013
negative regulation of cellular catabolic process GO:0031330 3 0.013
regulation of multicellular organism growth GO:0040014 4 0.013
receptor recycling GO:0001881 4 0.013
histone phosphorylation GO:0016572 2 0.013
regulation of gtp catabolic process GO:0033124 2 0.013
neurological system process GO:0050877 62 0.013
regulation of rna metabolic process GO:0051252 224 0.013
Zebrafish Mouse Fly
negative regulation of rna metabolic process GO:0051253 48 0.013
sequestering of calcium ion GO:0051208 3 0.013
mitotic cytokinesis GO:0000281 3 0.013
lipid metabolic process GO:0006629 52 0.013
rna biosynthetic process GO:0032774 181 0.013
Zebrafish Mouse Fly
primary neural tube formation GO:0014020 1 0.013
adherens junction organization GO:0034332 4 0.013
response to uv GO:0009411 3 0.013
proximal distal pattern formation GO:0009954 1 0.013
Mouse
regulation of inflammatory response GO:0050727 2 0.013
regulation of synaptic plasticity GO:0048167 1 0.013
calcium ion transport into cytosol GO:0060402 3 0.013
protein acylation GO:0043543 3 0.013
response to external stimulus GO:0009605 264 0.013
Zebrafish
regulation of sequestering of calcium ion GO:0051282 4 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.013
Zebrafish Mouse Fly
rna transport GO:0050658 2 0.013
regulation of protein targeting GO:1903533 2 0.013
vasculature development GO:0001944 278 0.013
cell projection morphogenesis GO:0048858 244 0.013
Zebrafish
digestive tract development GO:0048565 265 0.012
negative regulation of stem cell differentiation GO:2000737 2 0.012
positive regulation of cytoskeleton organization GO:0051495 3 0.012
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 0.012
response to endogenous stimulus GO:0009719 83 0.012
regulation of filopodium assembly GO:0051489 2 0.012
cellular response to stress GO:0033554 62 0.012
regulation of neuronal synaptic plasticity GO:0048168 1 0.012
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.012
centrosome cycle GO:0007098 1 0.012
centrosome organization GO:0051297 1 0.012
cellular response to lipid GO:0071396 39 0.012
embryonic heart tube development GO:0035050 133 0.012
protein dephosphorylation GO:0006470 3 0.012
regulation of cellular response to growth factor stimulus GO:0090287 35 0.012
axon development GO:0061564 166 0.012
Zebrafish
peptide metabolic process GO:0006518 1 0.012
establishment of protein localization to plasma membrane GO:0090002 1 0.012
renal system process involved in regulation of systemic arterial blood pressure GO:0003071 1 0.012
cell adhesion GO:0007155 40 0.012
single organism organelle organization GO:1902589 199 0.012
dicarboxylic acid transport GO:0006835 1 0.012
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.012
maternal determination of anterior posterior axis embryo GO:0008358 4 0.012
heart contraction GO:0060047 71 0.012
tube closure GO:0060606 1 0.012
negative regulation of autophagy GO:0010507 1 0.012
protein secretion GO:0009306 1 0.012
regulation of erk1 and erk2 cascade GO:0070372 4 0.012
localization within membrane GO:0051668 1 0.012
glucose homeostasis GO:0042593 1 0.012
retina development in camera type eye GO:0060041 146 0.012
regulation of cytokine production GO:0001817 3 0.012
negative regulation of rna biosynthetic process GO:1902679 45 0.012
negative regulation of protein kinase activity GO:0006469 4 0.012
macroautophagy GO:0016236 1 0.012
positive regulation of cellular process GO:0048522 201 0.012
Zebrafish Mouse Fly
cellular localization GO:0051641 97 0.012
Fly
phosphorus metabolic process GO:0006793 109 0.012
regulation of receptor mediated endocytosis GO:0048259 4 0.012
retinoid metabolic process GO:0001523 15 0.012
regulation of cardiac muscle contraction GO:0055117 2 0.012
head development GO:0060322 303 0.012
negative regulation of sequestering of calcium ion GO:0051283 4 0.012
cellular nitrogen compound catabolic process GO:0044270 15 0.012
determination of bilateral symmetry GO:0009855 204 0.012
alcohol biosynthetic process GO:0046165 2 0.012
protein import GO:0017038 3 0.012
Fly
regulation of gtpase activity GO:0043087 2 0.012
digestive system development GO:0055123 289 0.012
regulation of cellular component organization GO:0051128 86 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.011
regulation of organ growth GO:0046620 3 0.011
positive regulation of protein polymerization GO:0032273 2 0.011
translational initiation GO:0006413 3 0.011
recombinational repair GO:0000725 1 0.011
response to drug GO:0042493 3 0.011
cell cycle process GO:0022402 53 0.011
regulation of neurotransmitter transport GO:0051588 1 0.011
positive regulation of immune effector process GO:0002699 3 0.011
centrosome duplication GO:0051298 1 0.011
negative regulation of chromosome organization GO:2001251 1 0.011
cell killing GO:0001906 2 0.011
regulation of striated muscle contraction GO:0006942 2 0.011
neuron projection development GO:0031175 180 0.011
Zebrafish
muscle structure development GO:0061061 196 0.011
protein polymerization GO:0051258 4 0.011
purine containing compound metabolic process GO:0072521 29 0.011
female meiotic division GO:0007143 2 0.011
female gonad development GO:0008585 4 0.011
double strand break repair via homologous recombination GO:0000724 1 0.011
axonogenesis GO:0007409 152 0.011
Zebrafish
cell matrix adhesion GO:0007160 4 0.011
fin morphogenesis GO:0033334 53 0.011
skeletal system morphogenesis GO:0048705 102 0.011
Zebrafish
negative regulation of cellular biosynthetic process GO:0031327 55 0.011
inositol lipid mediated signaling GO:0048017 2 0.011
positive regulation of synapse assembly GO:0051965 1 0.011
segmentation GO:0035282 97 0.011
mononuclear cell proliferation GO:0032943 1 0.011
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.011
regulation of protein polymerization GO:0032271 2 0.011
blood circulation GO:0008015 87 0.011
determination of left right symmetry GO:0007368 179 0.011
lipid oxidation GO:0034440 1 0.011
cytoskeleton organization GO:0007010 96 0.011
synaptic vesicle localization GO:0097479 1 0.011
isoprenoid metabolic process GO:0006720 15 0.011
response to wounding GO:0009611 116 0.011
hindbrain development GO:0030902 91 0.011
Zebrafish
developmental growth GO:0048589 166 0.011
specification of symmetry GO:0009799 204 0.011
toll like receptor signaling pathway GO:0002224 4 0.011
terpenoid metabolic process GO:0006721 15 0.011
cellular response to radiation GO:0071478 4 0.011
positive regulation of multi organism process GO:0043902 3 0.010
pharyngeal muscle development GO:0043282 4 0.010
fatty acid beta oxidation GO:0006635 1 0.010
sensory organ development GO:0007423 393 0.010
sensory organ morphogenesis GO:0090596 200 0.010
development of primary female sexual characteristics GO:0046545 4 0.010
monocarboxylic acid catabolic process GO:0072329 3 0.010
positive regulation of gene expression GO:0010628 71 0.010
Zebrafish Mouse Fly
regulation of cellular component movement GO:0051270 55 0.010
carbohydrate derivative biosynthetic process GO:1901137 43 0.010
muscle cell differentiation GO:0042692 139 0.010
positive regulation of rna metabolic process GO:0051254 59 0.010
Zebrafish Mouse Fly
regulation of cell morphogenesis GO:0022604 42 0.010
regulation of tube size GO:0035150 2 0.010
regulation of cell activation GO:0050865 1 0.010
regulation of chromosome segregation GO:0051983 1 0.010
positive regulation of transcription dna templated GO:0045893 57 0.010
Zebrafish Mouse Fly

pbx2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.021
disease of anatomical entity DOID:7 0 0.021
musculoskeletal system disease DOID:17 0 0.016
physical disorder DOID:0080015 0 0.015
inherited metabolic disorder DOID:655 0 0.011
myopathy DOID:423 0 0.011
muscular disease DOID:0080000 0 0.011
muscle tissue disease DOID:66 0 0.011