Danio rerio

0 known processes

psmf1

proteasome (prosome, macropain) inhibitor subunit 1

(Aliases: zgc:92785)

psmf1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.084
modification dependent protein catabolic process GO:0019941 3 0.063
aging GO:0007568 2 0.062
signal transduction GO:0007165 455 0.058
cellular protein catabolic process GO:0044257 4 0.056
cellular nitrogen compound metabolic process GO:0034641 290 0.054
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.052
organelle fusion GO:0048284 3 0.049
proteasomal protein catabolic process GO:0010498 2 0.048
modification dependent macromolecule catabolic process GO:0043632 3 0.047
ubiquitin dependent protein catabolic process GO:0006511 3 0.047
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.042
multicellular organism growth GO:0035264 4 0.041
meiotic nuclear division GO:0007126 4 0.040
establishment of localization GO:0051234 244 0.037
membrane fusion GO:0061025 2 0.036
regulation of macromolecule metabolic process GO:0060255 317 0.035
i kappab kinase nf kappab signaling GO:0007249 4 0.035
regulation of response to stimulus GO:0048583 269 0.032
regulation of multicellular organism growth GO:0040014 4 0.031
regulation of metabolic process GO:0019222 359 0.031
gtp catabolic process GO:0006184 2 0.030
protein metabolic process GO:0019538 183 0.030
cellular protein metabolic process GO:0044267 129 0.029
single organism membrane fusion GO:0044801 2 0.029
gtp metabolic process GO:0046039 4 0.029
regulation of establishment of protein localization GO:0070201 4 0.029
mitochondrion organization GO:0007005 4 0.029
regulation of purine nucleotide catabolic process GO:0033121 2 0.028
establishment of protein localization to organelle GO:0072594 4 0.028
gene expression GO:0010467 252 0.028
protein localization to nucleus GO:0034504 3 0.027
single organism metabolic process GO:0044710 217 0.026
guanosine containing compound metabolic process GO:1901068 4 0.026
positive regulation of catabolic process GO:0009896 4 0.025
guanosine containing compound catabolic process GO:1901069 2 0.025
amine metabolic process GO:0009308 2 0.025
cellular response to extracellular stimulus GO:0031668 2 0.025
spermatid differentiation GO:0048515 2 0.025
positive regulation of cell cycle GO:0045787 3 0.024
mitotic dna integrity checkpoint GO:0044774 4 0.024
regulation of nucleoside metabolic process GO:0009118 2 0.024
regulation of cell communication GO:0010646 232 0.024
cellular amine metabolic process GO:0044106 2 0.024
cellular macromolecule metabolic process GO:0044260 391 0.024
nuclear transport GO:0051169 4 0.024
cellular response to external stimulus GO:0071496 2 0.023
carboxylic acid metabolic process GO:0019752 22 0.023
endosomal transport GO:0016197 2 0.023
nucleocytoplasmic transport GO:0006913 4 0.022
regulation of synapse organization GO:0050807 3 0.022
autophagy GO:0006914 4 0.022
regulation of signaling GO:0023051 235 0.022
response to drug GO:0042493 3 0.022
positive regulation of secretion GO:0051047 1 0.022
cellular biosynthetic process GO:0044249 286 0.022
morphogenesis of an epithelium GO:0002009 333 0.022
positive regulation of cellular catabolic process GO:0031331 3 0.022
regulation of cellular amine metabolic process GO:0033238 0 0.022
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.021
maintenance of location GO:0051235 4 0.021
positive regulation of transport GO:0051050 2 0.021
regulation of nucleotide catabolic process GO:0030811 2 0.021
intracellular signal transduction GO:0035556 85 0.021
organonitrogen compound metabolic process GO:1901564 74 0.021
nuclear import GO:0051170 3 0.021
regulation of binding GO:0051098 3 0.021
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.021
macromolecule biosynthetic process GO:0009059 227 0.020
cellular ketone metabolic process GO:0042180 11 0.020
negative regulation of signal transduction GO:0009968 94 0.020
lipid storage GO:0019915 1 0.020
regulation of meiotic cell cycle GO:0051445 1 0.020
cytokinesis GO:0000910 3 0.020
synaptic vesicle transport GO:0048489 1 0.020
regulation of reproductive process GO:2000241 4 0.020
organic substance biosynthetic process GO:1901576 289 0.020
establishment of synaptic vesicle localization GO:0097480 1 0.020
hormone secretion GO:0046879 2 0.020
positive regulation of cytokine production GO:0001819 2 0.020
cognition GO:0050890 1 0.019
rna localization GO:0006403 4 0.019
negative regulation of signaling GO:0023057 96 0.019
regulation of signal transduction GO:0009966 225 0.019
nucleobase containing compound biosynthetic process GO:0034654 205 0.019
cellular response to nutrient levels GO:0031669 2 0.019
mitotic dna damage checkpoint GO:0044773 4 0.019
regulation of cell activation GO:0050865 1 0.019
negative regulation of protein kinase activity GO:0006469 4 0.019
regulation of cellular amino acid metabolic process GO:0006521 0 0.019
stem cell proliferation GO:0072089 4 0.019
negative regulation of mapk cascade GO:0043409 4 0.019
negative regulation of response to stimulus GO:0048585 104 0.019
atp catabolic process GO:0006200 4 0.018
lateral inhibition GO:0046331 1 0.018
regulation of synapse assembly GO:0051963 3 0.018
sensory organ development GO:0007423 393 0.018
synaptic vesicle localization GO:0097479 1 0.018
regulation of nitrogen compound metabolic process GO:0051171 251 0.018
response to organic substance GO:0010033 153 0.018
secondary metabolic process GO:0019748 3 0.018
regulation of cytokine production GO:0001817 3 0.018
protein targeting to nucleus GO:0044744 3 0.018
convergent extension GO:0060026 118 0.018
protein secretion GO:0009306 1 0.018
cellular amino acid metabolic process GO:0006520 7 0.018
nitrogen compound metabolic process GO:0006807 319 0.018
cellular response to starvation GO:0009267 1 0.018
regulation of protein transport GO:0051223 3 0.018
phagocytosis GO:0006909 3 0.018
protein import GO:0017038 3 0.018
cell aging GO:0007569 2 0.018
protein import into nucleus GO:0006606 3 0.017
single organism nuclear import GO:1902593 3 0.017
regulation of metal ion transport GO:0010959 4 0.017
hormone transport GO:0009914 2 0.017
regulation of synaptic plasticity GO:0048167 1 0.017
positive regulation of secretion by cell GO:1903532 1 0.017
regulation of protein complex assembly GO:0043254 3 0.017
peptide transport GO:0015833 1 0.017
extrinsic apoptotic signaling pathway GO:0097191 3 0.017
oxoacid metabolic process GO:0043436 31 0.017
immune system process GO:0002376 241 0.017
regulation of protein catabolic process GO:0042176 1 0.017
neurotransmitter secretion GO:0007269 2 0.017
positive regulation of nucleoside metabolic process GO:0045979 1 0.017
positive regulation of cellular component biogenesis GO:0044089 3 0.017
negative regulation of protein phosphorylation GO:0001933 4 0.017
organic acid metabolic process GO:0006082 31 0.016
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.016
cellular component movement GO:0006928 335 0.016
positive regulation of cell activation GO:0050867 1 0.016
adult behavior GO:0030534 2 0.016
transcription from rna polymerase ii promoter GO:0006366 80 0.016
regulation of transcription dna templated GO:0006355 213 0.016
negative regulation of kinase activity GO:0033673 4 0.016
regulation of gtpase activity GO:0043087 2 0.016
type b pancreatic cell development GO:0003323 4 0.016
phosphorus metabolic process GO:0006793 109 0.016
multi organism process GO:0051704 134 0.016
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.016
small molecule metabolic process GO:0044281 77 0.016
g2 dna damage checkpoint GO:0031572 3 0.016
meiotic chromosome segregation GO:0045132 3 0.015
pole plasm assembly GO:0007315 4 0.015
regulation of cytoplasmic transport GO:1903649 4 0.015
organic cyclic compound biosynthetic process GO:1901362 223 0.015
endoplasmic reticulum unfolded protein response GO:0030968 2 0.015
protein polyubiquitination GO:0000209 4 0.015
spermatid development GO:0007286 2 0.015
regulation of cellular ketone metabolic process GO:0010565 7 0.015
transport GO:0006810 220 0.015
synaptic growth at neuromuscular junction GO:0051124 2 0.015
cellular amide metabolic process GO:0043603 4 0.015
response to chemical GO:0042221 320 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.015
cell substrate adhesion GO:0031589 4 0.015
response to uv GO:0009411 3 0.015
cellular aromatic compound metabolic process GO:0006725 295 0.015
regulation of gtp catabolic process GO:0033124 2 0.015
ribonucleoside monophosphate catabolic process GO:0009158 4 0.015
positive regulation of cellular amine metabolic process GO:0033240 0 0.015
protein localization to plasma membrane GO:0072659 1 0.015
meiotic cell cycle process GO:1903046 3 0.015
cellular macromolecule biosynthetic process GO:0034645 224 0.015
regulation of primary metabolic process GO:0080090 311 0.014
maternal determination of anterior posterior axis embryo GO:0008358 4 0.014
response to stress GO:0006950 263 0.014
oocyte anterior posterior axis specification GO:0007314 4 0.014
determination of left right symmetry GO:0007368 179 0.014
response to topologically incorrect protein GO:0035966 2 0.014
regulation of stem cell differentiation GO:2000736 4 0.014
negative regulation of cell communication GO:0010648 96 0.014
nucleobase containing compound metabolic process GO:0006139 274 0.014
regulation of multicellular organismal process GO:0051239 277 0.014
mononuclear cell proliferation GO:0032943 1 0.014
peptidyl serine phosphorylation GO:0018105 1 0.014
nucleic acid metabolic process GO:0090304 244 0.014
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.014
regulation of protein targeting GO:1903533 2 0.014
heterocycle biosynthetic process GO:0018130 215 0.014
adherens junction organization GO:0034332 4 0.014
cellular transition metal ion homeostasis GO:0046916 3 0.014
heart development GO:0007507 313 0.014
protein acetylation GO:0006473 2 0.014
positive regulation of cellular process GO:0048522 201 0.014
negative regulation of map kinase activity GO:0043407 2 0.014
protein stabilization GO:0050821 2 0.014
regulation of intracellular protein transport GO:0033157 3 0.014
b cell activation GO:0042113 2 0.014
hemopoiesis GO:0030097 183 0.014
primary neural tube formation GO:0014020 1 0.013
female sex differentiation GO:0046660 4 0.013
embryo development ending in birth or egg hatching GO:0009792 271 0.013
organelle organization GO:0006996 227 0.013
response to external stimulus GO:0009605 264 0.013
cell surface receptor signaling pathway GO:0007166 325 0.013
mitotic g2 dna damage checkpoint GO:0007095 3 0.013
cytoplasm organization GO:0007028 4 0.013
cellular response to topologically incorrect protein GO:0035967 2 0.013
gland development GO:0048732 143 0.013
eye development GO:0001654 277 0.013
positive regulation of apoptotic signaling pathway GO:2001235 1 0.013
regulation of stem cell proliferation GO:0072091 2 0.013
macromolecule modification GO:0043412 111 0.013
nucleoside monophosphate catabolic process GO:0009125 4 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.013
negative regulation of biological process GO:0048519 304 0.013
regulation of rna metabolic process GO:0051252 224 0.013
membrane invagination GO:0010324 1 0.013
negative regulation of gene expression GO:0010629 65 0.013
cytoskeleton dependent cytokinesis GO:0061640 3 0.013
compound eye development GO:0048749 2 0.013
liver development GO:0001889 96 0.013
microtubule organizing center organization GO:0031023 1 0.013
response to external biotic stimulus GO:0043207 97 0.013
regulation of intracellular signal transduction GO:1902531 57 0.013
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.013
viral process GO:0016032 1 0.013
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.013
heterocycle metabolic process GO:0046483 290 0.013
cellular component assembly GO:0022607 170 0.012
regulation of tube size GO:0035150 2 0.012
positive regulation of protein complex assembly GO:0031334 2 0.012
regulation of cellular metabolic process GO:0031323 320 0.012
peptide metabolic process GO:0006518 1 0.012
regulation of protein localization to nucleus GO:1900180 2 0.012
regulation of neurotransmitter transport GO:0051588 1 0.012
urogenital system development GO:0001655 97 0.012
regulation of cell substrate adhesion GO:0010810 1 0.012
cell cycle g1 s phase transition GO:0044843 1 0.012
small gtpase mediated signal transduction GO:0007264 8 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.012
multi organism cellular process GO:0044764 2 0.012
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.012
regulation of blood vessel size GO:0050880 2 0.012
protein homooligomerization GO:0051260 3 0.012
lipid catabolic process GO:0016042 4 0.012
cellular response to light stimulus GO:0071482 4 0.012
cell projection morphogenesis GO:0048858 244 0.012
immune system development GO:0002520 191 0.012
system process GO:0003008 185 0.012
regulation of neurotransmitter secretion GO:0046928 1 0.012
regulation of macromolecule biosynthetic process GO:0010556 225 0.012
rna transport GO:0050658 2 0.012
cell morphogenesis GO:0000902 289 0.012
growth GO:0040007 174 0.012
centrosome organization GO:0051297 1 0.012
rna metabolic process GO:0016070 219 0.012
regulation of hormone secretion GO:0046883 2 0.012
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.012
digestive tract development GO:0048565 265 0.012
intracellular mrna localization GO:0008298 1 0.012
development of primary female sexual characteristics GO:0046545 4 0.012
cellular response to chemical stimulus GO:0070887 157 0.012
regulation of blood pressure GO:0008217 1 0.012
leukocyte proliferation GO:0070661 1 0.012
synaptic vesicle recycling GO:0036465 1 0.012
negative regulation of cytoplasmic transport GO:1903650 2 0.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.012
organic cyclic compound metabolic process GO:1901360 301 0.012
hematopoietic or lymphoid organ development GO:0048534 191 0.011
vacuolar transport GO:0007034 2 0.011
post embryonic morphogenesis GO:0009886 4 0.011
positive regulation of cell adhesion GO:0045785 1 0.011
mitotic g2 m transition checkpoint GO:0044818 3 0.011
peptidyl lysine acetylation GO:0018394 2 0.011
internal protein amino acid acetylation GO:0006475 2 0.011
peptidyl serine modification GO:0018209 2 0.011
er nucleus signaling pathway GO:0006984 2 0.011
aromatic compound biosynthetic process GO:0019438 217 0.011
death GO:0016265 121 0.011
mitochondrial transport GO:0006839 2 0.011
positive regulation of map kinase activity GO:0043406 3 0.011
regulation of transmembrane transporter activity GO:0022898 2 0.011
nucleic acid transport GO:0050657 2 0.011
regulation of hematopoietic progenitor cell differentiation GO:1901532 1 0.011
neuron development GO:0048666 262 0.011
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.011
regulation of systemic arterial blood pressure GO:0003073 1 0.011
tissue remodeling GO:0048771 4 0.011
cellular nitrogen compound biosynthetic process GO:0044271 218 0.011
cellular localization GO:0051641 97 0.011
regulation of epithelial cell proliferation GO:0050678 3 0.011
positive regulation of stress activated mapk cascade GO:0032874 3 0.011
regulation of nucleocytoplasmic transport GO:0046822 2 0.011
exocytosis GO:0006887 1 0.011
cell matrix adhesion GO:0007160 4 0.011
interspecies interaction between organisms GO:0044419 4 0.011
cellular response to radiation GO:0071478 4 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.011
regulation of programmed cell death GO:0043067 101 0.011
regulation of biosynthetic process GO:0009889 250 0.011
regulation of dendrite development GO:0050773 3 0.011
spindle assembly involved in mitosis GO:0090307 1 0.011
negative regulation of nuclear division GO:0051784 3 0.011
regulation of protein binding GO:0043393 3 0.011
positive regulation of gtpase activity GO:0043547 1 0.011
synaptic vesicle endocytosis GO:0048488 1 0.011
regulation of ion transmembrane transporter activity GO:0032412 2 0.011
positive regulation of dna metabolic process GO:0051054 1 0.011
positive regulation of biological process GO:0048518 253 0.011
ribosomal small subunit biogenesis GO:0042274 2 0.011
establishment of rna localization GO:0051236 3 0.011
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.011
cellular component biogenesis GO:0044085 178 0.011
neurotransmitter transport GO:0006836 2 0.011
negative regulation of cellular catabolic process GO:0031330 3 0.011
regulation of rho protein signal transduction GO:0035023 2 0.011
programmed cell death GO:0012501 119 0.011
neuroblast proliferation GO:0007405 2 0.011
hepaticobiliary system development GO:0061008 98 0.010
response to nutrient GO:0007584 3 0.010
positive regulation of immune effector process GO:0002699 3 0.010
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.010
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.010
regulation of protein ubiquitination GO:0031396 3 0.010
apoptotic process involved in development GO:1902742 2 0.010
macroautophagy GO:0016236 1 0.010
iron ion homeostasis GO:0055072 4 0.010
positive regulation of nucleotide catabolic process GO:0030813 1 0.010
convergent extension involved in gastrulation GO:0060027 71 0.010
activation of mapk activity GO:0000187 3 0.010
histone h3 k4 methylation GO:0051568 2 0.010
dna biosynthetic process GO:0071897 3 0.010
erk1 and erk2 cascade GO:0070371 4 0.010
positive regulation of lipid metabolic process GO:0045834 1 0.010
cellular component disassembly GO:0022411 1 0.010
regulation of autophagy GO:0010506 3 0.010
developmental growth GO:0048589 166 0.010
response to corticosteroid GO:0031960 1 0.010
internal peptidyl lysine acetylation GO:0018393 2 0.010
negative regulation of multi organism process GO:0043901 3 0.010
regulation of neuronal synaptic plasticity GO:0048168 1 0.010
pharyngeal muscle development GO:0043282 4 0.010
positive regulation of muscle tissue development GO:1901863 1 0.010
response to unfolded protein GO:0006986 2 0.010
nucleic acid templated transcription GO:0097659 181 0.010
peptidyl threonine phosphorylation GO:0018107 1 0.010
lymphocyte proliferation GO:0046651 1 0.010
regulation of cellular protein catabolic process GO:1903362 1 0.010
positive regulation of cell substrate adhesion GO:0010811 1 0.010
establishment of protein localization to vacuole GO:0072666 1 0.010
cellular modified amino acid metabolic process GO:0006575 3 0.010
regulation of response to cytokine stimulus GO:0060759 3 0.010
regulation of gene expression GO:0010468 265 0.010

psmf1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.034
nervous system disease DOID:863 0 0.016
musculoskeletal system disease DOID:17 0 0.013
lysosomal storage disease DOID:3211 0 0.012
inherited metabolic disorder DOID:655 0 0.012
disease of metabolism DOID:0014667 0 0.012
disease of cellular proliferation DOID:14566 0 0.011
cancer DOID:162 0 0.011
organ system cancer DOID:0050686 0 0.010