Danio rerio

0 known processes

cybb

cytochrome b-245, beta polypeptide (chronic granulomatous disease)

(Aliases: MGC64144,zgc:64144)

cybb biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.106
regulation of biological quality GO:0065008 263 0.078
actin polymerization or depolymerization GO:0008154 2 0.067
cellular response to external stimulus GO:0071496 2 0.063
aging GO:0007568 2 0.063
regulation of macromolecule metabolic process GO:0060255 317 0.062
multicellular organism growth GO:0035264 4 0.059
positive regulation of cellular component biogenesis GO:0044089 3 0.059
establishment of protein localization to organelle GO:0072594 4 0.059
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.054
single organism localization GO:1902578 225 0.053
maintenance of location GO:0051235 4 0.051
cellular component morphogenesis GO:0032989 336 0.051
response to stress GO:0006950 263 0.051
Human Mouse
positive regulation of protein complex assembly GO:0031334 2 0.050
positive regulation of biological process GO:0048518 253 0.050
regulation of metabolic process GO:0019222 359 0.049
exocytosis GO:0006887 1 0.049
cell surface receptor signaling pathway GO:0007166 325 0.047
modification dependent macromolecule catabolic process GO:0043632 3 0.047
cellular amine metabolic process GO:0044106 2 0.047
regulation of reactive oxygen species metabolic process GO:2000377 2 0.046
embryonic organ development GO:0048568 381 0.045
negative regulation of cellular process GO:0048523 283 0.045
regulation of protein complex assembly GO:0043254 3 0.045
protein localization to nucleus GO:0034504 3 0.044
response to chemical GO:0042221 320 0.043
regulation of wound healing GO:0061041 2 0.043
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.043
regulation of multicellular organism growth GO:0040014 4 0.042
i kappab kinase nf kappab signaling GO:0007249 4 0.042
sensory organ development GO:0007423 393 0.042
nucleocytoplasmic transport GO:0006913 4 0.041
regulation of response to stimulus GO:0048583 269 0.041
response to drug GO:0042493 3 0.041
morphogenesis of an epithelium GO:0002009 333 0.041
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.041
protein secretion GO:0009306 1 0.040
small molecule metabolic process GO:0044281 77 0.040
single organism metabolic process GO:0044710 217 0.039
Human Mouse
protein targeting to nucleus GO:0044744 3 0.039
protein import into nucleus GO:0006606 3 0.039
cognition GO:0050890 1 0.039
positive regulation of transport GO:0051050 2 0.039
nuclear transport GO:0051169 4 0.039
cell projection organization GO:0030030 284 0.038
regulation of cellular amine metabolic process GO:0033238 0 0.038
regulation of cell communication GO:0010646 232 0.038
nitrogen compound metabolic process GO:0006807 319 0.038
cellular carbohydrate metabolic process GO:0044262 4 0.036
protein import GO:0017038 3 0.036
signal transduction GO:0007165 455 0.035
tube morphogenesis GO:0035239 349 0.035
cellular amino acid metabolic process GO:0006520 7 0.035
regulation of protein targeting GO:1903533 2 0.035
neuron differentiation GO:0030182 353 0.034
regulation of signaling GO:0023051 235 0.034
organic cyclic compound metabolic process GO:1901360 301 0.034
negative regulation of protein phosphorylation GO:0001933 4 0.034
regulation of protein import into nucleus GO:0042306 2 0.034
amine metabolic process GO:0009308 2 0.034
regulation of cellular metabolic process GO:0031323 320 0.033
regulation of synapse organization GO:0050807 3 0.033
regulation of nucleocytoplasmic transport GO:0046822 2 0.033
cellular component disassembly GO:0022411 1 0.033
regulation of signal transduction GO:0009966 225 0.033
single organism nuclear import GO:1902593 3 0.033
cellular ketone metabolic process GO:0042180 11 0.032
oxoacid metabolic process GO:0043436 31 0.032
regulation of multicellular organismal process GO:0051239 277 0.032
regulation of cellular amino acid metabolic process GO:0006521 0 0.032
biosynthetic process GO:0009058 294 0.032
Mouse
nuclear import GO:0051170 3 0.032
positive regulation of cellular amine metabolic process GO:0033240 0 0.032
carboxylic acid metabolic process GO:0019752 22 0.032
response to external stimulus GO:0009605 264 0.032
protein metabolic process GO:0019538 183 0.032
negative regulation of response to stimulus GO:0048585 104 0.031
positive regulation of cell cycle GO:0045787 3 0.031
cellular nitrogen compound metabolic process GO:0034641 290 0.031
regulation of cell activation GO:0050865 1 0.031
ubiquitin dependent protein catabolic process GO:0006511 3 0.031
cellular protein metabolic process GO:0044267 129 0.031
regulation of intracellular protein transport GO:0033157 3 0.031
protein complex disassembly GO:0043241 1 0.031
single organism organelle organization GO:1902589 199 0.031
cellular biosynthetic process GO:0044249 286 0.030
Mouse
macromolecular complex disassembly GO:0032984 1 0.030
b cell activation GO:0042113 2 0.030
regulation of primary metabolic process GO:0080090 311 0.030
tissue remodeling GO:0048771 4 0.030
regulation of protein transport GO:0051223 3 0.030
regulation of cytoplasmic transport GO:1903649 4 0.030
single organism transport GO:0044765 206 0.030
regulation of protein complex disassembly GO:0043244 1 0.030
guanosine containing compound catabolic process GO:1901069 2 0.030
cytokinesis GO:0000910 3 0.030
positive regulation of wound healing GO:0090303 1 0.030
regulation of biosynthetic process GO:0009889 250 0.029
regulation of establishment of protein localization GO:0070201 4 0.029
adult behavior GO:0030534 2 0.029
autophagy GO:0006914 4 0.029
positive regulation of map kinase activity GO:0043406 3 0.029
gtp catabolic process GO:0006184 2 0.029
cellular macromolecule metabolic process GO:0044260 391 0.029
regulation of protein localization to nucleus GO:1900180 2 0.029
embryo development ending in birth or egg hatching GO:0009792 271 0.029
organonitrogen compound metabolic process GO:1901564 74 0.028
gtp metabolic process GO:0046039 4 0.028
positive regulation of cellular process GO:0048522 201 0.028
regulation of developmental process GO:0050793 247 0.028
regulation of cellular ketone metabolic process GO:0010565 7 0.028
stem cell proliferation GO:0072089 4 0.028
positive regulation of cellular catabolic process GO:0031331 3 0.028
cortical actin cytoskeleton organization GO:0030866 1 0.028
cellular response to chemical stimulus GO:0070887 157 0.027
phagocytosis GO:0006909 3 0.027
response to alkaloid GO:0043279 2 0.027
organic acid metabolic process GO:0006082 31 0.027
cellular component biogenesis GO:0044085 178 0.027
response to glucocorticoid GO:0051384 1 0.027
generation of neurons GO:0048699 385 0.027
rna biosynthetic process GO:0032774 181 0.026
ion transport GO:0006811 114 0.026
response to corticosteroid GO:0031960 1 0.026
negative regulation of biological process GO:0048519 304 0.026
modification dependent protein catabolic process GO:0019941 3 0.026
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.026
rna localization GO:0006403 4 0.026
skeletal muscle tissue development GO:0007519 67 0.026
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.026
cellular response to biotic stimulus GO:0071216 3 0.025
monovalent inorganic cation transport GO:0015672 42 0.025
synaptic growth at neuromuscular junction GO:0051124 2 0.025
phosphorus metabolic process GO:0006793 109 0.025
cell part morphogenesis GO:0032990 246 0.025
oocyte anterior posterior axis specification GO:0007314 4 0.024
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.024
positive regulation of catabolic process GO:0009896 4 0.024
regulation of protein catabolic process GO:0042176 1 0.024
negative regulation of cell communication GO:0010648 96 0.024
phosphate containing compound metabolic process GO:0006796 108 0.024
muscle structure development GO:0061061 196 0.024
regulation of multicellular organismal development GO:2000026 223 0.024
transport GO:0006810 220 0.023
wound healing GO:0042060 90 0.023
homeostatic process GO:0042592 142 0.023
regulation of cell shape GO:0008360 1 0.023
skeletal muscle organ development GO:0060538 78 0.023
carbohydrate biosynthetic process GO:0016051 1 0.023
single organism biosynthetic process GO:0044711 71 0.023
positive regulation of cytoskeleton organization GO:0051495 3 0.023
regulation of dendrite development GO:0050773 3 0.023
membrane fusion GO:0061025 2 0.023
axon development GO:0061564 166 0.023
regulation of purine nucleotide catabolic process GO:0033121 2 0.022
protein polymerization GO:0051258 4 0.022
cellular component assembly GO:0022607 170 0.022
negative regulation of kinase activity GO:0033673 4 0.022
cellular protein catabolic process GO:0044257 4 0.022
regulation of synaptic plasticity GO:0048167 1 0.022
negative regulation of signal transduction GO:0009968 94 0.021
guanosine containing compound metabolic process GO:1901068 4 0.021
organelle fusion GO:0048284 3 0.021
immune system process GO:0002376 241 0.021
Human
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.021
regulation of reproductive process GO:2000241 4 0.021
synaptic vesicle transport GO:0048489 1 0.021
neuroblast proliferation GO:0007405 2 0.021
superoxide metabolic process GO:0006801 2 0.021
Human Mouse
growth GO:0040007 174 0.021
cellular protein modification process GO:0006464 100 0.021
regulation of catalytic activity GO:0050790 55 0.021
neuron development GO:0048666 262 0.021
digestive tract development GO:0048565 265 0.021
eye development GO:0001654 277 0.021
regulation of sequestering of calcium ion GO:0051282 4 0.021
ear development GO:0043583 127 0.021
multicellular organismal metabolic process GO:0044236 2 0.020
cellular aromatic compound metabolic process GO:0006725 295 0.020
positive regulation of cell activation GO:0050867 1 0.020
organelle assembly GO:0070925 110 0.020
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.020
response to carbohydrate GO:0009743 3 0.020
negative regulation of metabolic process GO:0009892 86 0.020
organic substance biosynthetic process GO:1901576 289 0.020
extrinsic apoptotic signaling pathway GO:0097191 3 0.020
central nervous system development GO:0007417 387 0.020
calcium ion transport into cytosol GO:0060402 3 0.020
cation transport GO:0006812 81 0.020
response to hydrogen peroxide GO:0042542 3 0.020
compound eye development GO:0048749 2 0.020
leukocyte proliferation GO:0070661 1 0.019
single organism membrane fusion GO:0044801 2 0.019
anion transport GO:0006820 38 0.019
proteasomal protein catabolic process GO:0010498 2 0.019
cellular response to extracellular stimulus GO:0031668 2 0.019
muscle organ development GO:0007517 101 0.019
macromolecule biosynthetic process GO:0009059 227 0.019
transmembrane transport GO:0055085 120 0.019
alcohol biosynthetic process GO:0046165 2 0.019
system process GO:0003008 185 0.019
cellular response to nutrient levels GO:0031669 2 0.019
negative regulation of mapk cascade GO:0043409 4 0.019
establishment of localization GO:0051234 244 0.019
biological adhesion GO:0022610 40 0.019
peptidyl serine modification GO:0018209 2 0.019
synaptic transmission cholinergic GO:0007271 4 0.018
heterocycle metabolic process GO:0046483 290 0.018
single fertilization GO:0007338 3 0.018
cellular response to starvation GO:0009267 1 0.018
endosomal transport GO:0016197 2 0.018
regulation of mrna processing GO:0050684 3 0.018
regulation of nitrogen compound metabolic process GO:0051171 251 0.018
developmental growth GO:0048589 166 0.018
cell projection morphogenesis GO:0048858 244 0.018
positive regulation of stress activated mapk cascade GO:0032874 3 0.018
cytoskeleton organization GO:0007010 96 0.018
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.018
immune system development GO:0002520 191 0.018
otic vesicle development GO:0071599 42 0.018
vasculature development GO:0001944 278 0.018
cell morphogenesis GO:0000902 289 0.018
synaptic vesicle localization GO:0097479 1 0.018
positive regulation of cytokine production GO:0001819 2 0.018
positive regulation of jnk cascade GO:0046330 3 0.018
nucleobase containing compound metabolic process GO:0006139 274 0.018
regulation of cytokine production GO:0001817 3 0.018
response to organic substance GO:0010033 153 0.018
response to endogenous stimulus GO:0009719 83 0.018
protein localization to plasma membrane GO:0072659 1 0.018
regulation of macromolecule biosynthetic process GO:0010556 225 0.018
muscle cell development GO:0055001 115 0.017
heart development GO:0007507 313 0.017
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.017
regulation of nucleotide catabolic process GO:0030811 2 0.017
positive regulation of secretion GO:0051047 1 0.017
embryonic organ morphogenesis GO:0048562 274 0.017
regulation of cellular biosynthetic process GO:0031326 245 0.017
negative regulation of catabolic process GO:0009895 3 0.017
head development GO:0060322 303 0.017
response to wounding GO:0009611 116 0.017
negative regulation of protein kinase activity GO:0006469 4 0.017
cytoplasm organization GO:0007028 4 0.017
organelle organization GO:0006996 227 0.017
determination of left right symmetry GO:0007368 179 0.017
cellular component movement GO:0006928 335 0.017
cellular macromolecule biosynthetic process GO:0034645 224 0.017
cellular localization GO:0051641 97 0.017
pancreas development GO:0031016 84 0.016
sequestering of metal ion GO:0051238 3 0.016
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.016
heterocycle biosynthetic process GO:0018130 215 0.016
negative regulation of cytokine production GO:0001818 1 0.016
cytoskeleton dependent cytokinesis GO:0061640 3 0.016
positive regulation of metabolic process GO:0009893 108 0.016
regulation of protein depolymerization GO:1901879 1 0.016
striated muscle cell differentiation GO:0051146 129 0.016
regulation of binding GO:0051098 3 0.016
neuron neuron synaptic transmission GO:0007270 1 0.016
locomotion GO:0040011 313 0.016
protein depolymerization GO:0051261 1 0.016
protein dephosphorylation GO:0006470 3 0.016
dicarboxylic acid transport GO:0006835 1 0.016
positive regulation of cell adhesion GO:0045785 1 0.016
regulation of anatomical structure morphogenesis GO:0022603 130 0.016
regulation of gene expression GO:0010468 265 0.016
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.016
multi organism process GO:0051704 134 0.015
hematopoietic or lymphoid organ development GO:0048534 191 0.015
cytosolic calcium ion transport GO:0060401 3 0.015
peptide transport GO:0015833 1 0.015
protein acetylation GO:0006473 2 0.015
ion homeostasis GO:0050801 41 0.015
cellular nitrogen compound biosynthetic process GO:0044271 218 0.015
amino acid transport GO:0006865 2 0.015
nuclear migration GO:0007097 3 0.015
macromolecule modification GO:0043412 111 0.015
positive regulation of immune effector process GO:0002699 3 0.015
polyol metabolic process GO:0019751 1 0.015
neurotransmitter transport GO:0006836 2 0.015
cellular component assembly involved in morphogenesis GO:0010927 107 0.015
regulation of nucleoside metabolic process GO:0009118 2 0.015
phosphorylation GO:0016310 69 0.015
hemopoiesis GO:0030097 183 0.015
striated muscle cell development GO:0055002 108 0.014
death GO:0016265 121 0.014
multicellular organismal macromolecule metabolic process GO:0044259 2 0.014
hemostasis GO:0007599 13 0.014
negative regulation of multicellular organismal process GO:0051241 69 0.014
rna metabolic process GO:0016070 219 0.014
chemosensory behavior GO:0007635 1 0.014
regulation of protein metabolic process GO:0051246 56 0.014
muscle cell differentiation GO:0042692 139 0.014
regulation of neurotransmitter secretion GO:0046928 1 0.014
actin filament based process GO:0030029 64 0.014
camera type eye development GO:0043010 222 0.014
protein acylation GO:0043543 3 0.014
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.014
cell cycle g1 s phase transition GO:0044843 1 0.014
regulation of tube size GO:0035150 2 0.014
regulation of molecular function GO:0065009 70 0.014
regulation of cell death GO:0010941 103 0.014
neurological system process GO:0050877 62 0.014
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.014
cellular response to organic substance GO:0071310 105 0.014
protein stabilization GO:0050821 2 0.014
brain development GO:0007420 293 0.014
cell death GO:0008219 121 0.014
neuron projection morphogenesis GO:0048812 161 0.014
cellular response to lipopolysaccharide GO:0071222 3 0.014
anterior posterior pattern specification GO:0009952 152 0.014
cation transmembrane transport GO:0098655 65 0.013
intracellular signal transduction GO:0035556 85 0.013
gene expression GO:0010467 252 0.013
regulation of neurotransmitter transport GO:0051588 1 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.013
neurotransmitter secretion GO:0007269 2 0.013
regulation of nucleic acid templated transcription GO:1903506 213 0.013
regulation of gtpase activity GO:0043087 2 0.013
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.013
aromatic compound biosynthetic process GO:0019438 217 0.013
axonogenesis GO:0007409 152 0.013
protein modification process GO:0036211 100 0.013
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.013
regionalization GO:0003002 274 0.013
lateral line system development GO:0048925 76 0.013
regulation of cell maturation GO:1903429 1 0.013
establishment of localization in cell GO:0051649 77 0.013
cellular response to reactive oxygen species GO:0034614 2 0.013
regulation of carbohydrate biosynthetic process GO:0043255 1 0.013
inner ear development GO:0048839 126 0.013
regulation of gtp catabolic process GO:0033124 2 0.013
striated muscle tissue development GO:0014706 110 0.013
chloride transmembrane transport GO:1902476 4 0.013
response to uv GO:0009411 3 0.013
response to inorganic substance GO:0010035 38 0.013
transcription dna templated GO:0006351 181 0.013
cell motility GO:0048870 244 0.013
response to organic cyclic compound GO:0014070 51 0.013
cilium morphogenesis GO:0060271 85 0.013
cell morphogenesis involved in differentiation GO:0000904 195 0.013
regulation of blood vessel size GO:0050880 2 0.013
mononuclear cell proliferation GO:0032943 1 0.013
fertilization GO:0009566 3 0.013
cellular response to stress GO:0033554 62 0.013
regulation of autophagy GO:0010506 3 0.013
regulation of protein polymerization GO:0032271 2 0.012
negative regulation of signaling GO:0023057 96 0.012
response to abiotic stimulus GO:0009628 122 0.012
intracellular mrna localization GO:0008298 1 0.012
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.012
pole plasm assembly GO:0007315 4 0.012
negative regulation of map kinase activity GO:0043407 2 0.012
macromolecular complex subunit organization GO:0043933 74 0.012
regulation of myotube differentiation GO:0010830 2 0.012
regulation of microtubule cytoskeleton organization GO:0070507 3 0.012
regulation of exocytosis GO:0017157 1 0.012
activation of mapk activity GO:0000187 3 0.012
cellular protein complex disassembly GO:0043624 1 0.012
negative regulation of chromosome organization GO:2001251 1 0.012
regulation of synapse assembly GO:0051963 3 0.012
establishment of synaptic vesicle localization GO:0097480 1 0.012
regulation of blood coagulation GO:0030193 1 0.012
liver development GO:0001889 96 0.012
regulation of cellular component organization GO:0051128 86 0.012
blood coagulation GO:0007596 12 0.012
apoptotic process GO:0006915 116 0.012
bone remodeling GO:0046849 2 0.012
adherens junction organization GO:0034332 4 0.012
retina development in camera type eye GO:0060041 146 0.012
regulation of phosphorus metabolic process GO:0051174 43 0.012
regulation of cell development GO:0060284 100 0.012
response to amino acid GO:0043200 2 0.012
circulatory system process GO:0003013 87 0.012
regulation of metal ion transport GO:0010959 4 0.012
erk1 and erk2 cascade GO:0070371 4 0.011
stem cell maintenance GO:0019827 4 0.011
regulation of hemostasis GO:1900046 1 0.011
negative regulation of cellular catabolic process GO:0031330 3 0.011
g1 s transition of mitotic cell cycle GO:0000082 1 0.011
mitotic dna integrity checkpoint GO:0044774 4 0.011
positive regulation of lipid metabolic process GO:0045834 1 0.011
convergent extension GO:0060026 118 0.011
response to bacterium GO:0009617 58 0.011
digestive system development GO:0055123 289 0.011
enzyme linked receptor protein signaling pathway GO:0007167 106 0.011
chordate embryonic development GO:0043009 271 0.011
negative regulation of phosphate metabolic process GO:0045936 13 0.011
nucleic acid metabolic process GO:0090304 244 0.011
digestive tract morphogenesis GO:0048546 231 0.011
heart process GO:0003015 71 0.011
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.011
peptidyl lysine acetylation GO:0018394 2 0.011
meiotic cell cycle process GO:1903046 3 0.011
lymphocyte proliferation GO:0046651 1 0.011
actin filament polymerization GO:0030041 2 0.011
sensory organ morphogenesis GO:0090596 200 0.011
response to biotic stimulus GO:0009607 97 0.011
regulation of calcium ion transport GO:0051924 2 0.011
metal ion transport GO:0030001 58 0.010
muscle tissue development GO:0060537 110 0.010
cell adhesion GO:0007155 40 0.010
cell cycle arrest GO:0007050 1 0.010
cell substrate adhesion GO:0031589 4 0.010
hepaticobiliary system development GO:0061008 98 0.010
cellular lipid metabolic process GO:0044255 36 0.010
negative regulation of programmed cell death GO:0043069 58 0.010
positive regulation of cell communication GO:0010647 56 0.010
negative regulation of cell death GO:0060548 60 0.010
response to hexose GO:0009746 3 0.010
regulation of cellular protein catabolic process GO:1903362 1 0.010
inorganic cation transmembrane transport GO:0098662 50 0.010
regulation of coagulation GO:0050818 2 0.010
organic acid catabolic process GO:0016054 3 0.010
retina morphogenesis in camera type eye GO:0060042 79 0.010
sequestering of calcium ion GO:0051208 3 0.010
regulation of tissue remodeling GO:0034103 2 0.010

cybb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.044
Human
cancer DOID:162 0 0.036
disease of cellular proliferation DOID:14566 0 0.036
organ system cancer DOID:0050686 0 0.025
immune system disease DOID:2914 0 0.022
Human
nervous system disease DOID:863 0 0.019
disease of metabolism DOID:0014667 0 0.017
sensory system disease DOID:0050155 0 0.012
eye and adnexa disease DOID:1492 0 0.012
eye disease DOID:5614 0 0.012
hematopoietic system disease DOID:74 0 0.011
muscular disease DOID:0080000 0 0.011
musculoskeletal system disease DOID:17 0 0.011