Danio rerio

0 known processes

capn2b

calpain 2, (m/II) large subunit b

(Aliases: MGC174280,im:6908877,MGC109906,zgc:109906)

capn2b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
modification dependent protein catabolic process GO:0019941 3 0.424
cellular protein catabolic process GO:0044257 4 0.373
ubiquitin dependent protein catabolic process GO:0006511 3 0.231
central nervous system development GO:0007417 387 0.216
aging GO:0007568 2 0.205
modification dependent macromolecule catabolic process GO:0043632 3 0.197
regulation of synapse organization GO:0050807 3 0.184
embryonic organ development GO:0048568 381 0.180
larval development GO:0002164 2 0.180
regulation of chromosome segregation GO:0051983 1 0.170
cytokinetic process GO:0032506 2 0.159
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.153
alpha amino acid metabolic process GO:1901605 3 0.140
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.138
brain development GO:0007420 293 0.133
regulation of protein catabolic process GO:0042176 1 0.133
cellular aromatic compound metabolic process GO:0006725 295 0.126
protein metabolic process GO:0019538 183 0.116
regulation of synapse assembly GO:0051963 3 0.108
response to chemical GO:0042221 320 0.105
proteasomal protein catabolic process GO:0010498 2 0.102
positive regulation of biological process GO:0048518 253 0.087
Worm
signal transduction GO:0007165 455 0.083
small molecule metabolic process GO:0044281 77 0.080
sensory organ development GO:0007423 393 0.080
oocyte anterior posterior axis specification GO:0007314 4 0.079
muscle cell differentiation GO:0042692 139 0.079
transport GO:0006810 220 0.075
response to external biotic stimulus GO:0043207 97 0.074
cellular modified amino acid metabolic process GO:0006575 3 0.073
axon extension GO:0048675 45 0.068
cortical actin cytoskeleton organization GO:0030866 1 0.066
regulation of binding GO:0051098 3 0.066
response to external stimulus GO:0009605 264 0.058
multicellular organism growth GO:0035264 4 0.056
locomotor rhythm GO:0045475 3 0.053
response to stress GO:0006950 263 0.053
leukocyte proliferation GO:0070661 1 0.052
specification of symmetry GO:0009799 204 0.049
adult behavior GO:0030534 2 0.045
positive regulation of cellular process GO:0048522 201 0.045
Worm
tyrosine phosphorylation of stat protein GO:0007260 1 0.044
epithelial cell differentiation GO:0030855 116 0.042
cellular amino acid metabolic process GO:0006520 7 0.039
regulation of rac protein signal transduction GO:0035020 1 0.038
regulation of signaling GO:0023051 235 0.038
regulation of cell differentiation GO:0045595 142 0.036
small gtpase mediated signal transduction GO:0007264 8 0.036
hemopoiesis GO:0030097 183 0.035
maternal determination of anterior posterior axis embryo GO:0008358 4 0.035
regulation of cell shape GO:0008360 1 0.034
organic acid metabolic process GO:0006082 31 0.034
positive regulation of cellular component biogenesis GO:0044089 3 0.033
regulation of cytoplasmic transport GO:1903649 4 0.033
organelle localization GO:0051640 49 0.033
organic cyclic compound metabolic process GO:1901360 301 0.033
axonogenesis GO:0007409 152 0.033
gtp metabolic process GO:0046039 4 0.033
oxoacid metabolic process GO:0043436 31 0.032
multi organism process GO:0051704 134 0.032
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.032
heterocycle metabolic process GO:0046483 290 0.031
regulation of signal transduction GO:0009966 225 0.031
organelle fusion GO:0048284 3 0.030
gtp catabolic process GO:0006184 2 0.030
regulation of cell activation GO:0050865 1 0.030
intracellular signal transduction GO:0035556 85 0.030
peptide metabolic process GO:0006518 1 0.030
cellular response to lipopolysaccharide GO:0071222 3 0.030
cofactor metabolic process GO:0051186 15 0.030
amine metabolic process GO:0009308 2 0.030
cell proliferation GO:0008283 80 0.029
organonitrogen compound metabolic process GO:1901564 74 0.029
positive regulation of cell activation GO:0050867 1 0.029
establishment of vesicle localization GO:0051650 24 0.029
regulation of chromosome organization GO:0033044 5 0.029
regulation of nucleotide catabolic process GO:0030811 2 0.029
water homeostasis GO:0030104 4 0.029
synapse assembly GO:0007416 9 0.028
lipid storage GO:0019915 1 0.028
negative regulation of kinase activity GO:0033673 4 0.028
regulation of systemic arterial blood pressure GO:0003073 1 0.027
cell death GO:0008219 121 0.027
Worm
protein localization to nucleus GO:0034504 3 0.027
synaptic growth at neuromuscular junction GO:0051124 2 0.027
sister chromatid segregation GO:0000819 6 0.027
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.026
establishment of endothelial barrier GO:0061028 3 0.026
regulation of cell communication GO:0010646 232 0.026
cell matrix adhesion GO:0007160 4 0.026
ear morphogenesis GO:0042471 64 0.026
regulation of macromolecule metabolic process GO:0060255 317 0.026
maintenance of location GO:0051235 4 0.026
single organism localization GO:1902578 225 0.026
apoptotic signaling pathway GO:0097190 23 0.026
digestive tract development GO:0048565 265 0.025
protein targeting to nucleus GO:0044744 3 0.025
developmental growth GO:0048589 166 0.025
cytokinesis GO:0000910 3 0.025
mitotic cell cycle process GO:1903047 48 0.025
adherens junction organization GO:0034332 4 0.025
cell projection organization GO:0030030 284 0.025
nuclear division GO:0000280 23 0.025
multicellular organism reproduction GO:0032504 35 0.025
cellular macromolecule biosynthetic process GO:0034645 224 0.025
regulation of primary metabolic process GO:0080090 311 0.024
biosynthetic process GO:0009058 294 0.024
axon development GO:0061564 166 0.024
positive regulation of apoptotic process GO:0043065 29 0.024
regulation of cellular biosynthetic process GO:0031326 245 0.024
cell part morphogenesis GO:0032990 246 0.023
b cell activation GO:0042113 2 0.023
establishment of protein localization to organelle GO:0072594 4 0.023
actin polymerization or depolymerization GO:0008154 2 0.023
epidermis development GO:0008544 48 0.023
positive regulation of cell matrix adhesion GO:0001954 1 0.023
death GO:0016265 121 0.023
Worm
response to glucose GO:0009749 3 0.022
cell cycle g1 s phase transition GO:0044843 1 0.022
cellular amine metabolic process GO:0044106 2 0.022
morphogenesis of an epithelium GO:0002009 333 0.022
response to abiotic stimulus GO:0009628 122 0.022
regulation of protein localization to nucleus GO:1900180 2 0.022
tyrosine phosphorylation of stat3 protein GO:0042503 1 0.022
cellular response to molecule of bacterial origin GO:0071219 3 0.021
carboxylic acid metabolic process GO:0019752 22 0.021
lymphocyte proliferation GO:0046651 1 0.021
positive regulation of cell cycle GO:0045787 3 0.020
axon ensheathment in central nervous system GO:0032291 2 0.020
nucleobase containing compound biosynthetic process GO:0034654 205 0.020
secondary metabolic process GO:0019748 3 0.020
cellular biosynthetic process GO:0044249 286 0.020
inner ear development GO:0048839 126 0.020
heterocycle biosynthetic process GO:0018130 215 0.020
nuclear import GO:0051170 3 0.020
cellular respiration GO:0045333 3 0.019
regulation of cellular amine metabolic process GO:0033238 0 0.019
nucleoside phosphate metabolic process GO:0006753 28 0.019
protein localization to plasma membrane GO:0072659 1 0.019
organelle fission GO:0048285 23 0.019
regulation of apoptotic process GO:0042981 98 0.019
g1 s transition of mitotic cell cycle GO:0000082 1 0.019
ribose phosphate metabolic process GO:0019693 27 0.019
programmed cell death GO:0012501 119 0.018
myotube differentiation GO:0014902 45 0.018
receptor internalization GO:0031623 2 0.018
segmentation GO:0035282 97 0.018
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.018
cellular response to chemical stimulus GO:0070887 157 0.018
mitotic sister chromatid segregation GO:0000070 6 0.018
regulation of protein transport GO:0051223 3 0.018
regulation of establishment of protein localization GO:0070201 4 0.018
cellular response to stress GO:0033554 62 0.018
positive regulation of apoptotic signaling pathway GO:2001235 1 0.017
lipid homeostasis GO:0055088 3 0.017
embryonic pattern specification GO:0009880 44 0.017
positive regulation of signaling GO:0023056 56 0.017
establishment of localization in cell GO:0051649 77 0.017
eye development GO:0001654 277 0.017
regulation of protein import into nucleus GO:0042306 2 0.017
response to organic substance GO:0010033 153 0.017
carbohydrate derivative biosynthetic process GO:1901137 43 0.017
anterior posterior axis specification GO:0009948 20 0.017
phosphate containing compound metabolic process GO:0006796 108 0.017
regulation of vesicle mediated transport GO:0060627 9 0.017
cellular macromolecule metabolic process GO:0044260 391 0.017
positive regulation of protein complex assembly GO:0031334 2 0.017
macromolecule biosynthetic process GO:0009059 227 0.016
head development GO:0060322 303 0.016
production of molecular mediator of immune response GO:0002440 2 0.016
cell substrate junction assembly GO:0007044 2 0.016
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.016
organelle organization GO:0006996 227 0.016
cell migration involved in gastrulation GO:0042074 79 0.016
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.016
organism emergence from protective structure GO:0071684 4 0.015
response to nutrient GO:0007584 3 0.015
cortical cytoskeleton organization GO:0030865 1 0.015
collagen biosynthetic process GO:0032964 2 0.015
positive regulation of metabolic process GO:0009893 108 0.015
response to metal ion GO:0010038 34 0.015
chemotaxis GO:0006935 104 0.015
protein complex localization GO:0031503 1 0.015
generation of neurons GO:0048699 385 0.015
cellular macromolecule catabolic process GO:0044265 12 0.015
positive regulation of cellular catabolic process GO:0031331 3 0.014
regulation of nitrogen compound metabolic process GO:0051171 251 0.014
regionalization GO:0003002 274 0.014
aromatic compound biosynthetic process GO:0019438 217 0.014
synaptic vesicle localization GO:0097479 1 0.014
regulation of blood vessel size GO:0050880 2 0.014
cellular nitrogen compound metabolic process GO:0034641 290 0.014
regulation of dna metabolic process GO:0051052 11 0.014
regulation of dendrite development GO:0050773 3 0.014
gland development GO:0048732 143 0.014
organic cyclic compound biosynthetic process GO:1901362 223 0.014
regulation of nucleoside metabolic process GO:0009118 2 0.014
regulation of nucleocytoplasmic transport GO:0046822 2 0.014
antimicrobial humoral response GO:0019730 2 0.014
skeletal system development GO:0001501 181 0.014
muscle structure development GO:0061061 196 0.014
organic substance biosynthetic process GO:1901576 289 0.014
single organism membrane organization GO:0044802 20 0.014
purine ribonucleotide metabolic process GO:0009150 27 0.014
single organism transport GO:0044765 206 0.014
hatching GO:0035188 4 0.014
regulation of cellular component organization GO:0051128 86 0.014
regulation of biological quality GO:0065008 263 0.014
cellular response to external stimulus GO:0071496 2 0.014
epidermal cell differentiation GO:0009913 36 0.014
regulation of metabolic process GO:0019222 359 0.013
negative regulation of protein kinase activity GO:0006469 4 0.013
long chain fatty acid metabolic process GO:0001676 1 0.013
negative regulation of i kappab kinase nf kappab signaling GO:0043124 1 0.013
regulation of tyrosine phosphorylation of stat3 protein GO:0042516 1 0.013
tube morphogenesis GO:0035239 349 0.013
regulation of immune system process GO:0002682 34 0.013
regulation of epithelial cell proliferation GO:0050678 3 0.013
negative regulation of protein phosphorylation GO:0001933 4 0.013
cell projection assembly GO:0030031 64 0.013
meiotic nuclear division GO:0007126 4 0.013
cellular response to extracellular stimulus GO:0031668 2 0.013
gene expression GO:0010467 252 0.013
myeloid cell homeostasis GO:0002262 56 0.013
epithelial cell development GO:0002064 42 0.013
negative regulation of intracellular protein transport GO:0090317 3 0.013
negative regulation of cell differentiation GO:0045596 46 0.013
positive regulation of cytoskeleton organization GO:0051495 3 0.013
transcription from rna polymerase ii promoter GO:0006366 80 0.012
cellular amino acid biosynthetic process GO:0008652 2 0.012
regulation of protein ubiquitination GO:0031396 3 0.012
regulation of cellular metabolic process GO:0031323 320 0.012
nuclear transport GO:0051169 4 0.012
transmission of nerve impulse GO:0019226 19 0.012
cell substrate adhesion GO:0031589 4 0.012
positive regulation of jnk cascade GO:0046330 3 0.012
endomembrane system organization GO:0010256 13 0.012
cellular protein metabolic process GO:0044267 129 0.012
positive regulation of transport GO:0051050 2 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
ear development GO:0043583 127 0.012
determination of bilateral symmetry GO:0009855 204 0.012
collagen metabolic process GO:0032963 2 0.012
positive regulation of protein polymerization GO:0032273 2 0.012
peptidyl tyrosine dephosphorylation GO:0035335 1 0.012
regulation of response to stimulus GO:0048583 269 0.012
response to transition metal nanoparticle GO:1990267 28 0.012
behavior GO:0007610 74 0.012
inorganic ion transmembrane transport GO:0098660 57 0.012
positive regulation of stress activated mapk cascade GO:0032874 3 0.011
proteolysis GO:0006508 38 0.011
positive regulation of nucleoside metabolic process GO:0045979 1 0.011
regulation of cellular protein catabolic process GO:1903362 1 0.011
intestinal absorption GO:0050892 2 0.011
germ line stem cell division GO:0042078 1 0.011
protein heterooligomerization GO:0051291 1 0.011
microglia differentiation GO:0014004 1 0.011
response to hypoxia GO:0001666 25 0.011
response to glucocorticoid GO:0051384 1 0.011
neuron development GO:0048666 262 0.011
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.011
embryonic axis specification GO:0000578 12 0.011
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.011
regulation of inflammatory response GO:0050727 2 0.011
positive regulation of production of molecular mediator of immune response GO:0002702 1 0.011
embryonic organ morphogenesis GO:0048562 274 0.011
macromolecular complex subunit organization GO:0043933 74 0.011
regulation of organ growth GO:0046620 3 0.011
stem cell differentiation GO:0048863 117 0.011
sensory organ morphogenesis GO:0090596 200 0.011
regulation of gtpase activity GO:0043087 2 0.011
triglyceride homeostasis GO:0070328 2 0.011
cellular response to biotic stimulus GO:0071216 3 0.011
startle response GO:0001964 4 0.011
chemosensory behavior GO:0007635 1 0.011
response to ethanol GO:0045471 6 0.011
regulation of cell proliferation GO:0042127 37 0.010
guanosine containing compound catabolic process GO:1901069 2 0.010
rna biosynthetic process GO:0032774 181 0.010
i kappab kinase nf kappab signaling GO:0007249 4 0.010
single organism metabolic process GO:0044710 217 0.010
ras protein signal transduction GO:0007265 7 0.010
positive regulation of chromosome segregation GO:0051984 1 0.010
sexual reproduction GO:0019953 36 0.010
negative regulation of epithelial cell proliferation GO:0050680 1 0.010
dorsal ventral pattern formation GO:0009953 125 0.010
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.010

capn2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.015
cancer DOID:162 0 0.015
disease of cellular proliferation DOID:14566 0 0.015