Danio rerio

0 known processes

capn2a

calpain 2, (m/II) large subunit a

(Aliases: zgc:113590)

capn2a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
digestive tract morphogenesis GO:0048546 231 0.121
protein import GO:0017038 3 0.118
aging GO:0007568 2 0.101
larval development GO:0002164 2 0.095
positive regulation of cellular component biogenesis GO:0044089 3 0.094
central nervous system development GO:0007417 387 0.080
protein localization to nucleus GO:0034504 3 0.072
regulation of cell shape GO:0008360 1 0.071
cell part morphogenesis GO:0032990 246 0.070
anterior posterior pattern specification GO:0009952 152 0.066
protein import into nucleus GO:0006606 3 0.066
digestive system development GO:0055123 289 0.063
generation of neurons GO:0048699 385 0.062
cellular component movement GO:0006928 335 0.062
reflex GO:0060004 2 0.061
gland development GO:0048732 143 0.057
embryo development ending in birth or egg hatching GO:0009792 271 0.056
axonogenesis GO:0007409 152 0.055
positive regulation of catabolic process GO:0009896 4 0.054
response to external stimulus GO:0009605 264 0.052
cell morphogenesis involved in differentiation GO:0000904 195 0.052
response to chemical GO:0042221 320 0.051
regulation of synapse organization GO:0050807 3 0.051
stem cell maintenance GO:0019827 4 0.050
head development GO:0060322 303 0.050
brain development GO:0007420 293 0.050
cellular response to lipopolysaccharide GO:0071222 3 0.049
nucleocytoplasmic transport GO:0006913 4 0.049
digestive tract development GO:0048565 265 0.048
regulation of synapse assembly GO:0051963 3 0.048
cognition GO:0050890 1 0.048
response to organic substance GO:0010033 153 0.047
cell projection organization GO:0030030 284 0.047
nuclear transport GO:0051169 4 0.046
tube morphogenesis GO:0035239 349 0.045
regulation of autophagy GO:0010506 3 0.045
cell matrix adhesion GO:0007160 4 0.045
regulation of cellular amine metabolic process GO:0033238 0 0.044
positive regulation of cellular catabolic process GO:0031331 3 0.043
cell morphogenesis GO:0000902 289 0.042
cell substrate adhesion GO:0031589 4 0.042
regulation of purine nucleotide catabolic process GO:0033121 2 0.041
cellular response to molecule of bacterial origin GO:0071219 3 0.041
somatic muscle development GO:0007525 4 0.041
single organism nuclear import GO:1902593 3 0.041
chordate embryonic development GO:0043009 271 0.041
positive regulation of epithelial cell proliferation GO:0050679 1 0.039
sensory organ development GO:0007423 393 0.038
response to monosaccharide GO:0034284 3 0.038
cell cycle GO:0007049 93 0.038
maintenance of location GO:0051235 4 0.037
cellular response to chemical stimulus GO:0070887 157 0.037
multicellular organism growth GO:0035264 4 0.036
establishment of protein localization to organelle GO:0072594 4 0.036
regulation of establishment of protein localization GO:0070201 4 0.036
somite development GO:0061053 96 0.035
regulation of cytoplasmic transport GO:1903649 4 0.035
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.035
nuclear import GO:0051170 3 0.035
stem cell division GO:0017145 1 0.034
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.034
protein targeting to nucleus GO:0044744 3 0.033
gastrulation GO:0007369 208 0.033
macroautophagy GO:0016236 1 0.033
localization of cell GO:0051674 244 0.033
regulation of nucleocytoplasmic transport GO:0046822 2 0.032
response to endogenous stimulus GO:0009719 83 0.032
amine metabolic process GO:0009308 2 0.032
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.032
carboxylic acid metabolic process GO:0019752 22 0.032
central nervous system neuron axonogenesis GO:0021955 18 0.031
central nervous system projection neuron axonogenesis GO:0021952 15 0.031
zymogen activation GO:0031638 3 0.030
regulation of protein transport GO:0051223 3 0.030
dorsal ventral pattern formation GO:0009953 125 0.030
morphogenesis of an epithelium GO:0002009 333 0.029
cellular response to external stimulus GO:0071496 2 0.029
cellular component morphogenesis GO:0032989 336 0.029
chemotaxis GO:0006935 104 0.029
cellular response to starvation GO:0009267 1 0.028
regulation of nucleotide catabolic process GO:0030811 2 0.028
cellular amine metabolic process GO:0044106 2 0.028
regulation of protein targeting GO:1903533 2 0.028
synaptic growth at neuromuscular junction GO:0051124 2 0.028
chemosensory behavior GO:0007635 1 0.028
positive regulation of map kinase activity GO:0043406 3 0.027
single organism metabolic process GO:0044710 217 0.027
blood vessel development GO:0001568 246 0.027
gtp metabolic process GO:0046039 4 0.027
guanosine containing compound metabolic process GO:1901068 4 0.027
neuron projection development GO:0031175 180 0.027
locomotor rhythm GO:0045475 3 0.027
regulation of multicellular organism growth GO:0040014 4 0.027
response to glucose GO:0009749 3 0.026
autophagy GO:0006914 4 0.026
neuroblast proliferation GO:0007405 2 0.026
cell migration involved in gastrulation GO:0042074 79 0.026
lipid storage GO:0019915 1 0.026
b cell activation GO:0042113 2 0.026
stem cell proliferation GO:0072089 4 0.025
ras protein signal transduction GO:0007265 7 0.025
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.025
adult behavior GO:0030534 2 0.025
segmentation GO:0035282 97 0.025
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.024
cellular respiration GO:0045333 3 0.024
negative regulation of synapse assembly GO:0051964 2 0.024
modification dependent protein catabolic process GO:0019941 3 0.024
positive regulation of striated muscle cell differentiation GO:0051155 1 0.024
neuron differentiation GO:0030182 353 0.024
eye development GO:0001654 277 0.024
gtp catabolic process GO:0006184 2 0.024
cellular response to extracellular stimulus GO:0031668 2 0.024
carbohydrate homeostasis GO:0033500 1 0.024
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.024
regulation of cellular amino acid metabolic process GO:0006521 0 0.024
phagocytosis GO:0006909 3 0.023
regulation of dendrite development GO:0050773 3 0.023
regulation of protein localization to nucleus GO:1900180 2 0.023
multi organism process GO:0051704 134 0.023
positive regulation of cell cycle GO:0045787 3 0.023
growth GO:0040007 174 0.023
positive regulation of transport GO:0051050 2 0.023
regulation of cell matrix adhesion GO:0001952 1 0.023
protein dephosphorylation GO:0006470 3 0.023
organic acid metabolic process GO:0006082 31 0.023
protein acylation GO:0043543 3 0.023
guanosine containing compound catabolic process GO:1901069 2 0.023
single organism organelle organization GO:1902589 199 0.022
response to nutrient GO:0007584 3 0.022
lamellipodium organization GO:0097581 1 0.022
positive regulation of nucleoside metabolic process GO:0045979 1 0.022
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.022
lipid homeostasis GO:0055088 3 0.022
secondary metabolic process GO:0019748 3 0.022
gene expression GO:0010467 252 0.022
regulation of cell projection assembly GO:0060491 4 0.022
regulation of dendrite morphogenesis GO:0048814 3 0.021
positive regulation of neuron death GO:1901216 1 0.021
heart development GO:0007507 313 0.021
organonitrogen compound metabolic process GO:1901564 74 0.021
ameboidal type cell migration GO:0001667 143 0.021
neuron projection morphogenesis GO:0048812 161 0.021
cell fate specification GO:0001708 68 0.021
regulation of photoreceptor cell differentiation GO:0046532 2 0.021
small molecule metabolic process GO:0044281 77 0.021
protein acetylation GO:0006473 2 0.021
regulation of cellular ketone metabolic process GO:0010565 7 0.021
cellular response to biotic stimulus GO:0071216 3 0.021
regulation of cardiac muscle tissue development GO:0055024 1 0.021
negative regulation of kinase activity GO:0033673 4 0.021
cell substrate junction assembly GO:0007044 2 0.021
rna localization GO:0006403 4 0.020
modification dependent macromolecule catabolic process GO:0043632 3 0.020
negative regulation of protein phosphorylation GO:0001933 4 0.020
positive regulation of nucleotide catabolic process GO:0030813 1 0.020
cell cycle g1 s phase transition GO:0044843 1 0.020
angiogenesis GO:0001525 158 0.020
proteasomal protein catabolic process GO:0010498 2 0.020
signal transduction GO:0007165 455 0.020
peptidyl lysine acetylation GO:0018394 2 0.020
positive regulation of muscle cell differentiation GO:0051149 1 0.020
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.020
locomotion GO:0040011 313 0.020
negative regulation of protein kinase activity GO:0006469 4 0.019
regulation of response to nutrient levels GO:0032107 1 0.019
mitochondrion organization GO:0007005 4 0.019
central nervous system neuron development GO:0021954 29 0.019
regulation of cell activation GO:0050865 1 0.019
positive regulation of protein complex assembly GO:0031334 2 0.019
regulation of protein complex assembly GO:0043254 3 0.019
muscle tissue development GO:0060537 110 0.019
cell surface receptor signaling pathway GO:0007166 325 0.019
regulation of developmental process GO:0050793 247 0.019
regulation of intracellular protein transport GO:0033157 3 0.019
glucose homeostasis GO:0042593 1 0.019
response to stress GO:0006950 263 0.019
oocyte maturation GO:0001556 4 0.018
regulation of protein catabolic process GO:0042176 1 0.018
death GO:0016265 121 0.018
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.018
positive regulation of biological process GO:0048518 253 0.018
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.018
regulation of binding GO:0051098 3 0.018
p38mapk cascade GO:0038066 1 0.018
cellular component disassembly GO:0022411 1 0.018
positive regulation of neuron apoptotic process GO:0043525 1 0.018
cellular nitrogen compound metabolic process GO:0034641 290 0.018
cellular aromatic compound metabolic process GO:0006725 295 0.018
cellular ketone metabolic process GO:0042180 11 0.018
regulation of cell substrate adhesion GO:0010810 1 0.018
centrosome organization GO:0051297 1 0.017
lamellipodium assembly GO:0030032 1 0.017
regulation of nucleoside metabolic process GO:0009118 2 0.017
negative regulation of cell differentiation GO:0045596 46 0.017
phosphate containing compound metabolic process GO:0006796 108 0.017
regulation of reactive oxygen species metabolic process GO:2000377 2 0.017
cellular macromolecule metabolic process GO:0044260 391 0.017
axon development GO:0061564 166 0.017
neuron neuron synaptic transmission GO:0007270 1 0.017
positive regulation of wound healing GO:0090303 1 0.017
cellular response to growth factor stimulus GO:0071363 39 0.017
regulation of gtp catabolic process GO:0033124 2 0.017
cellular response to endogenous stimulus GO:0071495 68 0.017
nucleic acid templated transcription GO:0097659 181 0.016
neuron development GO:0048666 262 0.016
response to external biotic stimulus GO:0043207 97 0.016
embryonic organ development GO:0048568 381 0.016
regulation of epithelial cell proliferation GO:0050678 3 0.016
axon guidance GO:0007411 86 0.016
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.016
b cell differentiation GO:0030183 1 0.016
purine nucleoside monophosphate catabolic process GO:0009128 4 0.016
response to hexose GO:0009746 3 0.016
nitrogen compound metabolic process GO:0006807 319 0.016
negative chemotaxis GO:0050919 1 0.016
axon extension GO:0048675 45 0.016
cellular amino acid metabolic process GO:0006520 7 0.016
protein secretion GO:0009306 1 0.016
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.016
cellular response to nutrient levels GO:0031669 2 0.016
tissue remodeling GO:0048771 4 0.016
regulation of gtpase activity GO:0043087 2 0.016
cell projection morphogenesis GO:0048858 244 0.016
response to abiotic stimulus GO:0009628 122 0.016
protein polymerization GO:0051258 4 0.016
regulation of protein import into nucleus GO:0042306 2 0.016
glial cell migration GO:0008347 3 0.015
regulation of synaptic plasticity GO:0048167 1 0.015
response to other organism GO:0051707 97 0.015
negative regulation of cytoplasmic transport GO:1903650 2 0.015
endothelial cell fate commitment GO:0060839 3 0.015
intracellular mrna localization GO:0008298 1 0.015
regulation of cell differentiation GO:0045595 142 0.015
cellular protein catabolic process GO:0044257 4 0.015
cell migration GO:0016477 237 0.015
oxoacid metabolic process GO:0043436 31 0.015
lateral inhibition GO:0046331 1 0.015
negative regulation of epithelial cell proliferation GO:0050680 1 0.015
actin polymerization or depolymerization GO:0008154 2 0.015
protein phosphorylation GO:0006468 47 0.015
developmental growth GO:0048589 166 0.015
small gtpase mediated signal transduction GO:0007264 8 0.015
cilium morphogenesis GO:0060271 85 0.015
vasculature development GO:0001944 278 0.015
regulation of cellular protein catabolic process GO:1903362 1 0.015
positive regulation of cell adhesion GO:0045785 1 0.015
signal transduction in absence of ligand GO:0038034 1 0.015
cellular carbohydrate metabolic process GO:0044262 4 0.015
antimicrobial humoral response GO:0019730 2 0.015
adherens junction organization GO:0034332 4 0.015
nuclear export GO:0051168 1 0.015
embryonic organ morphogenesis GO:0048562 274 0.015
regulation of inflammatory response GO:0050727 2 0.014
negative regulation of response to stimulus GO:0048585 104 0.014
protein homooligomerization GO:0051260 3 0.014
cell aging GO:0007569 2 0.014
urogenital system development GO:0001655 97 0.014
negative regulation of biological process GO:0048519 304 0.014
negative regulation of intracellular transport GO:0032387 3 0.014
cilium assembly GO:0042384 58 0.014
neuronal action potential GO:0019228 18 0.014
system process GO:0003008 185 0.014
internal peptidyl lysine acetylation GO:0018393 2 0.014
actin filament polymerization GO:0030041 2 0.014
internal protein amino acid acetylation GO:0006475 2 0.014
ubiquitin dependent protein catabolic process GO:0006511 3 0.014
determination of bilateral symmetry GO:0009855 204 0.014
programmed cell death GO:0012501 119 0.014
multicellular organismal signaling GO:0035637 22 0.014
multi organism cellular process GO:0044764 2 0.014
neurotransmitter transport GO:0006836 2 0.014
regulation of organelle assembly GO:1902115 4 0.014
protein metabolic process GO:0019538 183 0.014
phosphorus metabolic process GO:0006793 109 0.014
regulation of filopodium assembly GO:0051489 2 0.014
chromosome organization involved in meiosis GO:0070192 1 0.014
hair cell differentiation GO:0035315 32 0.014
neuron projection guidance GO:0097485 86 0.014
g1 s transition of mitotic cell cycle GO:0000082 1 0.013
phototransduction GO:0007602 2 0.013
meiotic cell cycle process GO:1903046 3 0.013
neural crest cell migration GO:0001755 42 0.013
positive regulation of apoptotic signaling pathway GO:2001235 1 0.013
neurotransmitter secretion GO:0007269 2 0.013
nucleoside monophosphate catabolic process GO:0009125 4 0.013
cell death GO:0008219 121 0.013
positive regulation of translation GO:0045727 1 0.013
regulation of erk1 and erk2 cascade GO:0070372 4 0.013
regulation of rho protein signal transduction GO:0035023 2 0.013
cellular response to organic substance GO:0071310 105 0.013
photoreceptor cell differentiation GO:0046530 55 0.013
axon ensheathment in central nervous system GO:0032291 2 0.013
regulation of transcription dna templated GO:0006355 213 0.013
meiotic nuclear division GO:0007126 4 0.013
atp catabolic process GO:0006200 4 0.013
pronephros development GO:0048793 69 0.013
regulation of metabolic process GO:0019222 359 0.013
cellular protein metabolic process GO:0044267 129 0.013
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.013
cellular response to hypoxia GO:0071456 1 0.013
biosynthetic process GO:0009058 294 0.013
protein complex localization GO:0031503 1 0.013
defense response to bacterium GO:0042742 22 0.013
organelle organization GO:0006996 227 0.013
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.013
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.012
meiotic chromosome segregation GO:0045132 3 0.012
muscle cell differentiation GO:0042692 139 0.012
regulation of primary metabolic process GO:0080090 311 0.012
actin cytoskeleton organization GO:0030036 63 0.012
negative regulation of defense response GO:0031348 2 0.012
bmp signaling pathway GO:0030509 52 0.012
regulation of production of molecular mediator of immune response GO:0002700 1 0.012
regulation of molecular function GO:0065009 70 0.012
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.012
ribonucleoside monophosphate catabolic process GO:0009158 4 0.012
convergent extension GO:0060026 118 0.012
response to biotic stimulus GO:0009607 97 0.012
regulation of cellular metabolic process GO:0031323 320 0.012
regulation of response to biotic stimulus GO:0002831 2 0.012
nucleic acid metabolic process GO:0090304 244 0.012
regulation of anatomical structure morphogenesis GO:0022603 130 0.012
positive regulation of muscle tissue development GO:1901863 1 0.012
immune system development GO:0002520 191 0.012
synaptic vesicle localization GO:0097479 1 0.012
response to transition metal nanoparticle GO:1990267 28 0.012
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.012
ear development GO:0043583 127 0.012
positive regulation of camp metabolic process GO:0030816 2 0.012
extrinsic apoptotic signaling pathway GO:0097191 3 0.012
actin mediated cell contraction GO:0070252 1 0.012
negative regulation of map kinase activity GO:0043407 2 0.012
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.012
regulation of neural precursor cell proliferation GO:2000177 3 0.012
taxis GO:0042330 109 0.012
positive regulation of gtp catabolic process GO:0033126 1 0.012
epidermal cell fate specification GO:0009957 4 0.012
peptidyl serine phosphorylation GO:0018105 1 0.012
gastrulation with mouth forming second GO:0001702 44 0.012
germ line stem cell division GO:0042078 1 0.012
negative regulation of intracellular protein transport GO:0090317 3 0.012
retina development in camera type eye GO:0060041 146 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
osteoclast differentiation GO:0030316 1 0.011
central nervous system neuron differentiation GO:0021953 74 0.011
i kappab kinase nf kappab signaling GO:0007249 4 0.011
regulation of signaling GO:0023051 235 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.011
regulation of signal transduction GO:0009966 225 0.011
protein localization to plasma membrane GO:0072659 1 0.011
viral process GO:0016032 1 0.011
cell motility GO:0048870 244 0.011
cortical cytoskeleton organization GO:0030865 1 0.011
regulation of multicellular organismal process GO:0051239 277 0.011
regulation of response to extracellular stimulus GO:0032104 1 0.011
cell projection assembly GO:0030031 64 0.011
negative regulation of ras protein signal transduction GO:0046580 1 0.011
production of molecular mediator of immune response GO:0002440 2 0.011
camera type eye development GO:0043010 222 0.011
negative regulation of mapk cascade GO:0043409 4 0.011
somitogenesis GO:0001756 87 0.011
negative regulation of protein import into nucleus GO:0042308 2 0.011
regulation of nervous system development GO:0051960 90 0.011
cellular response to fibroblast growth factor stimulus GO:0044344 22 0.011
regulation of neurotransmitter secretion GO:0046928 1 0.011
peptide transport GO:0015833 1 0.011
negative regulation of secretion by cell GO:1903531 2 0.011
positive regulation of protein polymerization GO:0032273 2 0.011
inositol lipid mediated signaling GO:0048017 2 0.011
specification of symmetry GO:0009799 204 0.011
heterocycle metabolic process GO:0046483 290 0.011
cytoplasm organization GO:0007028 4 0.011
cellular protein modification process GO:0006464 100 0.011
transmembrane transport GO:0055085 120 0.011
sensory perception of chemical stimulus GO:0007606 3 0.011
regulation of biosynthetic process GO:0009889 250 0.011
regulation of cell motility GO:2000145 46 0.011
startle response GO:0001964 4 0.011
erk1 and erk2 cascade GO:0070371 4 0.011
positive regulation of myeloid cell differentiation GO:0045639 2 0.011
regulation of multicellular organismal development GO:2000026 223 0.011
positive regulation of cytoskeleton organization GO:0051495 3 0.011
regulation of endothelial cell proliferation GO:0001936 1 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.011
regulation of fibroblast growth factor receptor signaling pathway GO:0040036 20 0.011
regulation of transmembrane transporter activity GO:0022898 2 0.011
protein modification process GO:0036211 100 0.011
endosomal transport GO:0016197 2 0.011
regulation of cell morphogenesis GO:0022604 42 0.011
regulation of cellular component organization GO:0051128 86 0.011
protein modification by small protein removal GO:0070646 1 0.011
positive regulation of multi organism process GO:0043902 3 0.011
blood vessel endothelial cell differentiation GO:0060837 2 0.011
interspecies interaction between organisms GO:0044419 4 0.011
microtubule based process GO:0007017 60 0.011
wound healing GO:0042060 90 0.011
response to bacterium GO:0009617 58 0.011
nephric duct development GO:0072176 13 0.011
negative regulation of autophagy GO:0010507 1 0.011
hepaticobiliary system development GO:0061008 98 0.011
nucleoside phosphate metabolic process GO:0006753 28 0.010
negative regulation of multi organism process GO:0043901 3 0.010
response to wounding GO:0009611 116 0.010
regulation of stem cell differentiation GO:2000736 4 0.010
rho protein signal transduction GO:0007266 5 0.010
camera type eye morphogenesis GO:0048593 108 0.010
sensory perception of smell GO:0007608 2 0.010
ventricular cardiac muscle tissue development GO:0003229 3 0.010
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.010
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.010
macromolecule modification GO:0043412 111 0.010
b cell mediated immunity GO:0019724 3 0.010
aromatic compound biosynthetic process GO:0019438 217 0.010
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.010
regulation of glial cell differentiation GO:0045685 4 0.010
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.010
cellular response to decreased oxygen levels GO:0036294 1 0.010
transcription dna templated GO:0006351 181 0.010
regulation of transporter activity GO:0032409 2 0.010
establishment of protein localization to plasma membrane GO:0090002 1 0.010
aorta morphogenesis GO:0035909 3 0.010
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.010
skeletal system development GO:0001501 181 0.010
pericardium development GO:0060039 1 0.010
liver development GO:0001889 96 0.010

capn2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.031
aplastic anemia DOID:12449 0 0.031
disease of anatomical entity DOID:7 0 0.031
bone marrow disease DOID:4961 0 0.031
anemia DOID:2355 0 0.031
hematopoietic system disease DOID:74 0 0.031
cancer DOID:162 0 0.019
disease of cellular proliferation DOID:14566 0 0.019
nervous system disease DOID:863 0 0.016
organ system cancer DOID:0050686 0 0.012