Danio rerio

0 known processes

rlf

rearranged L-myc fusion

(Aliases: si:ch211-154e15.8,im:7146976)

rlf biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular protein catabolic process GO:0044257 4 0.286
modification dependent protein catabolic process GO:0019941 3 0.237
ubiquitin dependent protein catabolic process GO:0006511 3 0.143
aging GO:0007568 2 0.113
larval development GO:0002164 2 0.112
multicellular organism growth GO:0035264 4 0.106
regulation of multicellular organism growth GO:0040014 4 0.105
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.095
heterocycle metabolic process GO:0046483 290 0.087
modification dependent macromolecule catabolic process GO:0043632 3 0.085
negative regulation of cellular process GO:0048523 283 0.077
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.075
regulation of programmed cell death GO:0043067 101 0.072
proteasomal protein catabolic process GO:0010498 2 0.068
vasculature development GO:0001944 278 0.066
regulation of protein localization to nucleus GO:1900180 2 0.056
negative regulation of gene expression GO:0010629 65 0.055
stem cell maintenance GO:0019827 4 0.052
nitrogen compound metabolic process GO:0006807 319 0.051
nuclear export GO:0051168 1 0.050
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.048
negative regulation of cellular metabolic process GO:0031324 77 0.048
nuclear transport GO:0051169 4 0.045
organic substance biosynthetic process GO:1901576 289 0.044
nucleocytoplasmic transport GO:0006913 4 0.043
cellular biosynthetic process GO:0044249 286 0.042
regulation of protein catabolic process GO:0042176 1 0.042
negative regulation of ras protein signal transduction GO:0046580 1 0.042
regulation of cell death GO:0010941 103 0.041
internal protein amino acid acetylation GO:0006475 2 0.040
regulation of establishment of protein localization GO:0070201 4 0.039
locomotion GO:0040011 313 0.038
regulation of protein import into nucleus GO:0042306 2 0.038
rna metabolic process GO:0016070 219 0.038
g2 dna damage checkpoint GO:0031572 3 0.037
regulation of nitrogen compound metabolic process GO:0051171 251 0.037
apoptotic process GO:0006915 116 0.036
chemosensory behavior GO:0007635 1 0.035
meiotic nuclear division GO:0007126 4 0.035
nuclear import GO:0051170 3 0.035
amine metabolic process GO:0009308 2 0.033
stem cell differentiation GO:0048863 117 0.032
establishment of localization GO:0051234 244 0.031
single organism nuclear import GO:1902593 3 0.031
negative regulation of signaling GO:0023057 96 0.031
regulation of protein targeting GO:1903533 2 0.031
rna localization GO:0006403 4 0.030
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.030
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.030
response to stress GO:0006950 263 0.030
cellular protein metabolic process GO:0044267 129 0.030
regulation of primary metabolic process GO:0080090 311 0.030
regulation of transcription dna templated GO:0006355 213 0.029
internal peptidyl lysine acetylation GO:0018393 2 0.029
regulation of protein ubiquitination GO:0031396 3 0.028
protein localization to nucleus GO:0034504 3 0.028
protein import into nucleus GO:0006606 3 0.028
regulation of cellular metabolic process GO:0031323 320 0.028
cognition GO:0050890 1 0.027
regulation of macromolecule metabolic process GO:0060255 317 0.027
regulation of cellular amino acid metabolic process GO:0006521 0 0.027
protein acetylation GO:0006473 2 0.027
negative regulation of biological process GO:0048519 304 0.027
protein polyubiquitination GO:0000209 4 0.026
cellular component disassembly GO:0022411 1 0.026
circadian sleep wake cycle GO:0042745 2 0.026
proteolysis GO:0006508 38 0.026
cellular macromolecule biosynthetic process GO:0034645 224 0.026
positive regulation of transport GO:0051050 2 0.026
cellular macromolecule catabolic process GO:0044265 12 0.025
protein import GO:0017038 3 0.025
organic cyclic compound biosynthetic process GO:1901362 223 0.025
cell migration GO:0016477 237 0.024
nucleic acid metabolic process GO:0090304 244 0.024
single organism metabolic process GO:0044710 217 0.024
macromolecular complex disassembly GO:0032984 1 0.024
regulation of cellular biosynthetic process GO:0031326 245 0.024
regulation of apoptotic process GO:0042981 98 0.023
protein targeting to nucleus GO:0044744 3 0.023
regulation of protein complex assembly GO:0043254 3 0.023
aromatic compound biosynthetic process GO:0019438 217 0.023
peptidyl lysine acetylation GO:0018394 2 0.023
protein complex disassembly GO:0043241 1 0.023
negative regulation of metabolic process GO:0009892 86 0.023
positive regulation of protein complex assembly GO:0031334 2 0.022
cell death GO:0008219 121 0.022
regulation of cellular protein catabolic process GO:1903362 1 0.022
g1 s transition of mitotic cell cycle GO:0000082 1 0.022
organelle organization GO:0006996 227 0.022
cellular amine metabolic process GO:0044106 2 0.022
single organism organelle organization GO:1902589 199 0.022
cellular component movement GO:0006928 335 0.022
stem cell division GO:0017145 1 0.022
cellular macromolecule metabolic process GO:0044260 391 0.021
positive regulation of cellular amine metabolic process GO:0033240 0 0.021
biosynthetic process GO:0009058 294 0.021
regulation of biosynthetic process GO:0009889 250 0.021
negative regulation of macromolecule metabolic process GO:0010605 76 0.021
cilium organization GO:0044782 71 0.021
cellular component morphogenesis GO:0032989 336 0.020
digestive tract development GO:0048565 265 0.020
nucleic acid templated transcription GO:0097659 181 0.020
immune system development GO:0002520 191 0.020
transcription from rna polymerase ii promoter GO:0006366 80 0.020
regulation of cell activation GO:0050865 1 0.020
protein metabolic process GO:0019538 183 0.020
positive regulation of histone modification GO:0031058 1 0.020
immune system process GO:0002376 241 0.020
negative regulation of response to stimulus GO:0048585 104 0.020
tube closure GO:0060606 1 0.020
mrna transport GO:0051028 2 0.020
neuron remodeling GO:0016322 1 0.020
mitotic cell cycle embryonic GO:0045448 2 0.020
single organism transport GO:0044765 206 0.020
positive regulation of cell activation GO:0050867 1 0.020
erythrocyte differentiation GO:0030218 54 0.020
embryo development ending in birth or egg hatching GO:0009792 271 0.020
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.020
regulation of cytoplasmic transport GO:1903649 4 0.019
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.019
maintenance of location GO:0051235 4 0.019
meiotic cell cycle process GO:1903046 3 0.019
protein acylation GO:0043543 3 0.019
negative regulation of protein phosphorylation GO:0001933 4 0.019
establishment of protein localization to organelle GO:0072594 4 0.019
death GO:0016265 121 0.019
positive regulation of metabolic process GO:0009893 108 0.019
regulation of reproductive process GO:2000241 4 0.019
cilium morphogenesis GO:0060271 85 0.019
covalent chromatin modification GO:0016569 20 0.019
skeletal system development GO:0001501 181 0.018
regulation of developmental process GO:0050793 247 0.018
positive regulation of cellular catabolic process GO:0031331 3 0.017
positive regulation of immune effector process GO:0002699 3 0.017
negative regulation of signal transduction GO:0009968 94 0.017
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.017
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.017
adult behavior GO:0030534 2 0.017
meiotic chromosome segregation GO:0045132 3 0.017
cellular ketone metabolic process GO:0042180 11 0.017
negative regulation of cellular biosynthetic process GO:0031327 55 0.017
regulation of protein transport GO:0051223 3 0.017
transcription dna templated GO:0006351 181 0.017
b cell activation GO:0042113 2 0.017
positive regulation of dna metabolic process GO:0051054 1 0.017
positive regulation of leukocyte differentiation GO:1902107 1 0.017
histone h3 k4 methylation GO:0051568 2 0.017
response to drug GO:0042493 3 0.017
cellular response to lipopolysaccharide GO:0071222 3 0.016
regulation of nucleocytoplasmic transport GO:0046822 2 0.016
neurological system process GO:0050877 62 0.016
regulation of macromolecule biosynthetic process GO:0010556 225 0.016
regulation of metabolic process GO:0019222 359 0.016
cellular nitrogen compound metabolic process GO:0034641 290 0.016
mesenchyme development GO:0060485 127 0.016
positive regulation of biological process GO:0048518 253 0.016
positive regulation of cell cycle GO:0045787 3 0.016
stem cell proliferation GO:0072089 4 0.016
mitotic dna damage checkpoint GO:0044773 4 0.016
cellular response to biotic stimulus GO:0071216 3 0.015
regulation of rna metabolic process GO:0051252 224 0.015
regulation of signal transduction GO:0009966 225 0.015
system process GO:0003008 185 0.015
regulation of dna replication GO:0006275 3 0.015
head development GO:0060322 303 0.015
tissue remodeling GO:0048771 4 0.015
chromosome organization involved in meiosis GO:0070192 1 0.015
response to hexose GO:0009746 3 0.015
female gonad development GO:0008585 4 0.015
generation of neurons GO:0048699 385 0.015
positive regulation of chromatin modification GO:1903310 1 0.015
regulation of cell shape GO:0008360 1 0.015
cellular protein modification process GO:0006464 100 0.015
nucleobase containing compound metabolic process GO:0006139 274 0.015
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.015
regulation of cellular ketone metabolic process GO:0010565 7 0.015
growth GO:0040007 174 0.015
neuron development GO:0048666 262 0.014
cellular response to external stimulus GO:0071496 2 0.014
glial cell proliferation GO:0014009 4 0.014
blood vessel development GO:0001568 246 0.014
ameboidal type cell migration GO:0001667 143 0.014
sensory organ development GO:0007423 393 0.014
regulation of cellular amine metabolic process GO:0033238 0 0.014
digestive system development GO:0055123 289 0.014
determination of bilateral symmetry GO:0009855 204 0.014
nucleobase containing compound transport GO:0015931 2 0.014
response to carbohydrate GO:0009743 3 0.014
primary neural tube formation GO:0014020 1 0.014
specification of symmetry GO:0009799 204 0.014
regulation of intracellular protein transport GO:0033157 3 0.014
macromolecule catabolic process GO:0009057 15 0.014
protein dephosphorylation GO:0006470 3 0.014
spermatid development GO:0007286 2 0.014
cellular response to molecule of bacterial origin GO:0071219 3 0.014
regulation of gene expression epigenetic GO:0040029 11 0.014
regulation of cell differentiation GO:0045595 142 0.014
stem cell development GO:0048864 82 0.014
myeloid cell differentiation GO:0030099 86 0.014
extrinsic apoptotic signaling pathway GO:0097191 3 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.013
positive regulation of cellular component biogenesis GO:0044089 3 0.013
cellular response to dna damage stimulus GO:0006974 24 0.013
positive regulation of chromosome organization GO:2001252 1 0.013
positive regulation of catabolic process GO:0009896 4 0.013
negative regulation of mapk cascade GO:0043409 4 0.013
cell matrix adhesion GO:0007160 4 0.013
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.013
chordate embryonic development GO:0043009 271 0.013
cell cycle g1 s phase transition GO:0044843 1 0.013
segmentation GO:0035282 97 0.013
positive regulation of multicellular organismal process GO:0051240 52 0.013
cellular protein complex disassembly GO:0043624 1 0.013
translational initiation GO:0006413 3 0.013
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.013
regulation of synapse assembly GO:0051963 3 0.013
negative regulation of rna metabolic process GO:0051253 48 0.013
peptide transport GO:0015833 1 0.012
transport GO:0006810 220 0.012
hemopoiesis GO:0030097 183 0.012
cell projection morphogenesis GO:0048858 244 0.012
gene expression GO:0010467 252 0.012
regulation of signaling GO:0023051 235 0.012
cardiac cell fate commitment GO:0060911 1 0.012
cell motility GO:0048870 244 0.012
cell part morphogenesis GO:0032990 246 0.012
macromolecule biosynthetic process GO:0009059 227 0.012
regulation of cell aging GO:0090342 1 0.012
regulation of cytokine production GO:0001817 3 0.012
cellular aromatic compound metabolic process GO:0006725 295 0.012
response to chemical GO:0042221 320 0.012
negative regulation of cell communication GO:0010648 96 0.012
positive regulation of rna biosynthetic process GO:1902680 57 0.012
cellular amino acid metabolic process GO:0006520 7 0.012
regulation of production of molecular mediator of immune response GO:0002700 1 0.012
heterocycle biosynthetic process GO:0018130 215 0.012
cell aging GO:0007569 2 0.012
cellular nitrogen compound biosynthetic process GO:0044271 218 0.012
catechol containing compound metabolic process GO:0009712 2 0.012
organic cyclic compound metabolic process GO:1901360 301 0.012
tube morphogenesis GO:0035239 349 0.012
regulation of chromosome segregation GO:0051983 1 0.012
somatic cell dna recombination GO:0016444 1 0.012
reactive oxygen species biosynthetic process GO:1903409 1 0.012
negative regulation of defense response GO:0031348 2 0.012
response to glucose GO:0009749 3 0.012
macromolecule modification GO:0043412 111 0.012
outflow tract morphogenesis GO:0003151 1 0.012
spindle assembly GO:0051225 2 0.011
positive regulation of myeloid cell differentiation GO:0045639 2 0.011
negative regulation of protein localization to nucleus GO:1900181 2 0.011
regulation of binding GO:0051098 3 0.011
er to golgi vesicle mediated transport GO:0006888 1 0.011
regulation of cell communication GO:0010646 232 0.011
neuroblast proliferation GO:0007405 2 0.011
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.011
positive regulation of macromolecule metabolic process GO:0010604 93 0.011
cellular response to radiation GO:0071478 4 0.011
camera type eye development GO:0043010 222 0.011
neuron differentiation GO:0030182 353 0.011
establishment of apical basal cell polarity GO:0035089 2 0.011
regulation of protein complex disassembly GO:0043244 1 0.011
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.011
oxoacid metabolic process GO:0043436 31 0.011
cytoskeleton dependent cytokinesis GO:0061640 3 0.011
cell morphogenesis GO:0000902 289 0.011
circadian sleep wake cycle sleep GO:0050802 1 0.011
regulation of rna biosynthetic process GO:2001141 213 0.011
protein modification process GO:0036211 100 0.011
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.011
response to monosaccharide GO:0034284 3 0.011
double strand break repair GO:0006302 3 0.011
protein homooligomerization GO:0051260 3 0.011
cellular response to starvation GO:0009267 1 0.011
blood vessel morphogenesis GO:0048514 216 0.011
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.011
negative regulation of cell differentiation GO:0045596 46 0.011
somatic stem cell maintenance GO:0035019 1 0.011
cartilage development GO:0051216 96 0.011
regulation of jak stat cascade GO:0046425 3 0.010
negative regulation of catabolic process GO:0009895 3 0.010
embryonic organ development GO:0048568 381 0.010
cellular component assembly involved in morphogenesis GO:0010927 107 0.010
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.010
regulation of gene expression GO:0010468 265 0.010
response to ketone GO:1901654 1 0.010
regulation of dna templated transcription elongation GO:0032784 3 0.010
negative regulation of cytokine mediated signaling pathway GO:0001960 2 0.010
female sex differentiation GO:0046660 4 0.010
sensory perception of touch GO:0050975 2 0.010
ear development GO:0043583 127 0.010

rlf disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.046
disease of cellular proliferation DOID:14566 0 0.046
disease of anatomical entity DOID:7 0 0.041
organ system cancer DOID:0050686 0 0.016
nervous system disease DOID:863 0 0.016