Danio rerio

0 known processes

tha1

threonine aldolase 1

(Aliases: zgc:91912)

tha1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.057
aging GO:0007568 2 0.045
positive regulation of transport GO:0051050 2 0.035
cellular biosynthetic process GO:0044249 286 0.035
multicellular organism growth GO:0035264 4 0.035
regulation of establishment of protein localization GO:0070201 4 0.034
cellular macromolecule metabolic process GO:0044260 391 0.034
regulation of multicellular organism growth GO:0040014 4 0.033
amine metabolic process GO:0009308 2 0.033
maintenance of location GO:0051235 4 0.033
phagocytosis GO:0006909 3 0.032
signal transduction GO:0007165 455 0.031
organic substance biosynthetic process GO:1901576 289 0.031
adult behavior GO:0030534 2 0.031
regulation of protein transport GO:0051223 3 0.031
cellular nitrogen compound metabolic process GO:0034641 290 0.031
cellular amine metabolic process GO:0044106 2 0.030
nitrogen compound metabolic process GO:0006807 319 0.030
positive regulation of cellular component biogenesis GO:0044089 3 0.028
cognition GO:0050890 1 0.028
response to chemical GO:0042221 320 0.028
positive regulation of cell cycle GO:0045787 3 0.028
establishment of protein localization to organelle GO:0072594 4 0.027
regulation of metabolic process GO:0019222 359 0.027
digestive system development GO:0055123 289 0.027
meiotic nuclear division GO:0007126 4 0.026
embryonic organ development GO:0048568 381 0.026
golgi vesicle transport GO:0048193 3 0.026
single organism metabolic process GO:0044710 217 0.026
regulation of synapse organization GO:0050807 3 0.026
cellular ketone metabolic process GO:0042180 11 0.026
organic cyclic compound metabolic process GO:1901360 301 0.026
regulation of primary metabolic process GO:0080090 311 0.025
protein localization to nucleus GO:0034504 3 0.025
negative regulation of protein phosphorylation GO:0001933 4 0.025
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.025
tube morphogenesis GO:0035239 349 0.025
regulation of cellular amine metabolic process GO:0033238 0 0.024
cellular component movement GO:0006928 335 0.024
extrinsic apoptotic signaling pathway GO:0097191 3 0.024
cytokinesis GO:0000910 3 0.024
generation of neurons GO:0048699 385 0.024
regulation of cellular metabolic process GO:0031323 320 0.024
heterocycle metabolic process GO:0046483 290 0.024
synaptic growth at neuromuscular junction GO:0051124 2 0.024
response to drug GO:0042493 3 0.024
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.023
gtp metabolic process GO:0046039 4 0.023
response to stress GO:0006950 263 0.023
ubiquitin dependent protein catabolic process GO:0006511 3 0.023
regulation of response to stimulus GO:0048583 269 0.023
single fertilization GO:0007338 3 0.023
cellular protein catabolic process GO:0044257 4 0.023
biosynthetic process GO:0009058 294 0.023
negative regulation of protein kinase activity GO:0006469 4 0.023
regulation of signal transduction GO:0009966 225 0.023
cellular response to external stimulus GO:0071496 2 0.023
regulation of meiotic cell cycle GO:0051445 1 0.023
establishment of protein localization to plasma membrane GO:0090002 1 0.023
cell surface receptor signaling pathway GO:0007166 325 0.023
positive regulation of catabolic process GO:0009896 4 0.022
rna metabolic process GO:0016070 219 0.022
regulation of cell activation GO:0050865 1 0.022
organonitrogen compound metabolic process GO:1901564 74 0.022
lipid storage GO:0019915 1 0.022
nuclear transport GO:0051169 4 0.022
regulation of cytokine production GO:0001817 3 0.022
regulation of cellular ketone metabolic process GO:0010565 7 0.022
cellular macromolecule biosynthetic process GO:0034645 224 0.022
modification dependent macromolecule catabolic process GO:0043632 3 0.022
regulation of signaling GO:0023051 235 0.022
neuron differentiation GO:0030182 353 0.022
cell migration GO:0016477 237 0.022
negative regulation of biological process GO:0048519 304 0.022
regulation of cellular amino acid metabolic process GO:0006521 0 0.022
regulation of nitrogen compound metabolic process GO:0051171 251 0.022
transcription dna templated GO:0006351 181 0.021
oxoacid metabolic process GO:0043436 31 0.021
positive regulation of biological process GO:0048518 253 0.021
modification dependent protein catabolic process GO:0019941 3 0.021
regulation of synapse assembly GO:0051963 3 0.021
regulation of cytoplasmic transport GO:1903649 4 0.021
chordate embryonic development GO:0043009 271 0.021
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.021
nucleobase containing compound metabolic process GO:0006139 274 0.021
gtp catabolic process GO:0006184 2 0.021
cellular amino acid metabolic process GO:0006520 7 0.021
carboxylic acid metabolic process GO:0019752 22 0.021
regulation of cellular biosynthetic process GO:0031326 245 0.021
regulation of metal ion transport GO:0010959 4 0.021
g1 s transition of mitotic cell cycle GO:0000082 1 0.021
protein import GO:0017038 3 0.021
organic acid metabolic process GO:0006082 31 0.021
macromolecule biosynthetic process GO:0009059 227 0.021
single organism localization GO:1902578 225 0.021
protein localization to plasma membrane GO:0072659 1 0.021
morphogenesis of an epithelium GO:0002009 333 0.021
cellular response to extracellular stimulus GO:0031668 2 0.021
gene expression GO:0010467 252 0.021
gastrulation GO:0007369 208 0.020
nucleocytoplasmic transport GO:0006913 4 0.020
mitochondrion organization GO:0007005 4 0.020
central nervous system development GO:0007417 387 0.020
proteasomal protein catabolic process GO:0010498 2 0.020
stem cell maintenance GO:0019827 4 0.020
cellular carbohydrate metabolic process GO:0044262 4 0.020
autophagy GO:0006914 4 0.020
positive regulation of cellular catabolic process GO:0031331 3 0.020
digestive tract morphogenesis GO:0048546 231 0.020
organelle fusion GO:0048284 3 0.020
negative regulation of kinase activity GO:0033673 4 0.020
locomotion GO:0040011 313 0.020
negative regulation of cellular process GO:0048523 283 0.019
regulation of reproductive process GO:2000241 4 0.019
exocytosis GO:0006887 1 0.019
cellular nitrogen compound biosynthetic process GO:0044271 218 0.019
establishment of localization GO:0051234 244 0.019
blood vessel development GO:0001568 246 0.019
positive regulation of cell activation GO:0050867 1 0.019
cellular response to nutrient levels GO:0031669 2 0.019
guanosine containing compound metabolic process GO:1901068 4 0.019
nucleobase containing compound biosynthetic process GO:0034654 205 0.019
eye development GO:0001654 277 0.019
guanosine containing compound catabolic process GO:1901069 2 0.019
digestive tract development GO:0048565 265 0.019
organic cyclic compound biosynthetic process GO:1901362 223 0.019
regulation of binding GO:0051098 3 0.019
regulation of intracellular protein transport GO:0033157 3 0.018
stem cell proliferation GO:0072089 4 0.018
cellular aromatic compound metabolic process GO:0006725 295 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.018
meiotic cell cycle process GO:1903046 3 0.018
ribonucleoside monophosphate catabolic process GO:0009158 4 0.018
regulation of macromolecule metabolic process GO:0060255 317 0.018
protein metabolic process GO:0019538 183 0.018
atp catabolic process GO:0006200 4 0.018
cellular component morphogenesis GO:0032989 336 0.018
compound eye development GO:0048749 2 0.018
cell substrate adhesion GO:0031589 4 0.018
regulation of biological quality GO:0065008 263 0.018
positive regulation of cellular amine metabolic process GO:0033240 0 0.018
fertilization GO:0009566 3 0.018
protein targeting to nucleus GO:0044744 3 0.018
camera type eye development GO:0043010 222 0.018
sensory organ development GO:0007423 393 0.018
organic acid catabolic process GO:0016054 3 0.018
single organism nuclear import GO:1902593 3 0.018
inositol lipid mediated signaling GO:0048017 2 0.018
vasculature development GO:0001944 278 0.018
cell part morphogenesis GO:0032990 246 0.018
cell projection organization GO:0030030 284 0.018
regulation of developmental process GO:0050793 247 0.018
regulation of cell communication GO:0010646 232 0.018
lateral inhibition GO:0046331 1 0.018
regulation of macromolecule biosynthetic process GO:0010556 225 0.018
rna biosynthetic process GO:0032774 181 0.018
positive regulation of secretion by cell GO:1903532 1 0.017
nucleoside monophosphate catabolic process GO:0009125 4 0.017
cytoskeleton dependent cytokinesis GO:0061640 3 0.017
heterocycle biosynthetic process GO:0018130 215 0.017
small molecule metabolic process GO:0044281 77 0.017
neuron development GO:0048666 262 0.017
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.017
specification of symmetry GO:0009799 204 0.017
single organism membrane fusion GO:0044801 2 0.017
cell projection morphogenesis GO:0048858 244 0.017
mononuclear cell proliferation GO:0032943 1 0.017
regulation of erk1 and erk2 cascade GO:0070372 4 0.017
secondary metabolic process GO:0019748 3 0.017
nuclear import GO:0051170 3 0.017
regulation of biosynthetic process GO:0009889 250 0.017
neuron neuron synaptic transmission GO:0007270 1 0.017
regulation of mrna processing GO:0050684 3 0.017
regulation of sequestering of calcium ion GO:0051282 4 0.017
cell morphogenesis GO:0000902 289 0.017
protein acetylation GO:0006473 2 0.017
phagocytosis engulfment GO:0006911 1 0.017
immune system process GO:0002376 241 0.017
cell motility GO:0048870 244 0.017
regulation of purine nucleotide catabolic process GO:0033121 2 0.017
regulation of protein complex assembly GO:0043254 3 0.017
aromatic compound biosynthetic process GO:0019438 217 0.017
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.017
positive regulation of secretion GO:0051047 1 0.017
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.016
erk1 and erk2 cascade GO:0070371 4 0.016
transport GO:0006810 220 0.016
neuroblast proliferation GO:0007405 2 0.016
homeostatic process GO:0042592 142 0.016
organelle organization GO:0006996 227 0.016
er to golgi vesicle mediated transport GO:0006888 1 0.016
regulation of nucleoside metabolic process GO:0009118 2 0.016
regulation of protein localization to nucleus GO:1900180 2 0.016
response to external stimulus GO:0009605 264 0.016
leukocyte proliferation GO:0070661 1 0.016
regulation of gene expression GO:0010468 265 0.016
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.016
cellular response to chemical stimulus GO:0070887 157 0.016
internal protein amino acid acetylation GO:0006475 2 0.016
peptidyl lysine acetylation GO:0018394 2 0.016
germ line stem cell maintenance GO:0030718 2 0.016
head development GO:0060322 303 0.016
membrane fusion GO:0061025 2 0.016
neurotransmitter transport GO:0006836 2 0.016
regionalization GO:0003002 274 0.016
cytoplasm organization GO:0007028 4 0.016
regulation of multicellular organismal process GO:0051239 277 0.015
endosomal transport GO:0016197 2 0.015
female sex differentiation GO:0046660 4 0.015
positive regulation of cytokine production GO:0001819 2 0.015
embryonic organ morphogenesis GO:0048562 274 0.015
purine nucleoside monophosphate catabolic process GO:0009128 4 0.015
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.015
protein secretion GO:0009306 1 0.015
negative regulation of mapk cascade GO:0043409 4 0.015
carboxylic acid catabolic process GO:0046395 3 0.015
positive regulation of cellular process GO:0048522 201 0.015
system process GO:0003008 185 0.015
protein import into nucleus GO:0006606 3 0.015
localization of cell GO:0051674 244 0.015
small molecule catabolic process GO:0044282 3 0.015
regulation of nucleocytoplasmic transport GO:0046822 2 0.015
sequestering of metal ion GO:0051238 3 0.015
membrane invagination GO:0010324 1 0.015
hemopoiesis GO:0030097 183 0.015
nucleic acid templated transcription GO:0097659 181 0.015
rna localization GO:0006403 4 0.015
regulation of nucleotide catabolic process GO:0030811 2 0.015
cellular response to starvation GO:0009267 1 0.015
synaptic vesicle localization GO:0097479 1 0.015
blood vessel morphogenesis GO:0048514 216 0.014
regulation of nucleic acid templated transcription GO:1903506 213 0.014
regulation of rna metabolic process GO:0051252 224 0.014
nucleic acid metabolic process GO:0090304 244 0.014
heart development GO:0007507 313 0.014
response to hexose GO:0009746 3 0.014
positive regulation of protein complex assembly GO:0031334 2 0.014
cell cycle g1 s phase transition GO:0044843 1 0.014
positive regulation of immune effector process GO:0002699 3 0.014
regulation of protein targeting GO:1903533 2 0.014
cellular protein metabolic process GO:0044267 129 0.014
anterior posterior pattern specification GO:0009952 152 0.014
regulation of rna biosynthetic process GO:2001141 213 0.014
phosphatidylinositol mediated signaling GO:0048015 2 0.014
regulation of autophagy GO:0010506 3 0.014
brain development GO:0007420 293 0.014
amino acid transport GO:0006865 2 0.014
protein acylation GO:0043543 3 0.014
regulation of synaptic plasticity GO:0048167 1 0.014
regulation of calcium ion transport GO:0051924 2 0.014
regulation of dendrite development GO:0050773 3 0.014
response to monosaccharide GO:0034284 3 0.014
protein dephosphorylation GO:0006470 3 0.014
alcohol biosynthetic process GO:0046165 2 0.014
stem cell division GO:0017145 1 0.014
single organism transport GO:0044765 206 0.014
regulation of protein catabolic process GO:0042176 1 0.014
positive regulation of cytoskeleton organization GO:0051495 3 0.014
protein complex disassembly GO:0043241 1 0.014
lymphocyte proliferation GO:0046651 1 0.014
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.014
single organism organelle organization GO:1902589 199 0.014
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.014
synaptic vesicle transport GO:0048489 1 0.014
convergent extension involved in gastrulation GO:0060027 71 0.014
adherens junction organization GO:0034332 4 0.014
mitochondrial transport GO:0006839 2 0.013
release of sequestered calcium ion into cytosol GO:0051209 3 0.013
negative regulation of sequestering of calcium ion GO:0051283 4 0.013
internal peptidyl lysine acetylation GO:0018393 2 0.013
cytosolic calcium ion transport GO:0060401 3 0.013
response to organic substance GO:0010033 153 0.013
cellular component disassembly GO:0022411 1 0.013
establishment of synaptic vesicle localization GO:0097480 1 0.013
regulation of multicellular organismal development GO:2000026 223 0.013
regulation of cell shape GO:0008360 1 0.013
negative regulation of protein transport GO:0051224 3 0.013
regulation of stem cell differentiation GO:2000736 4 0.013
cortical cytoskeleton organization GO:0030865 1 0.013
regulation of neural precursor cell proliferation GO:2000177 3 0.013
protein heterooligomerization GO:0051291 1 0.013
tissue remodeling GO:0048771 4 0.013
negative regulation of catabolic process GO:0009895 3 0.013
convergent extension GO:0060026 118 0.013
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.013
i kappab kinase nf kappab signaling GO:0007249 4 0.013
regulation of gtpase activity GO:0043087 2 0.013
spermatid differentiation GO:0048515 2 0.013
response to nutrient GO:0007584 3 0.013
embryo development ending in birth or egg hatching GO:0009792 271 0.013
retina development in camera type eye GO:0060041 146 0.013
maternal determination of anterior posterior axis embryo GO:0008358 4 0.013
developmental growth GO:0048589 166 0.013
skeletal system development GO:0001501 181 0.013
spermatid development GO:0007286 2 0.013
sensory organ morphogenesis GO:0090596 200 0.013
protein homooligomerization GO:0051260 3 0.013
signal transduction in absence of ligand GO:0038034 1 0.012
cellular component assembly GO:0022607 170 0.012
cellular amide metabolic process GO:0043603 4 0.012
positive regulation of cell adhesion GO:0045785 1 0.012
regulation of transcription dna templated GO:0006355 213 0.012
regulation of inflammatory response GO:0050727 2 0.012
carbohydrate biosynthetic process GO:0016051 1 0.012
post golgi vesicle mediated transport GO:0006892 1 0.012
muscle structure development GO:0061061 196 0.012
response to glucose GO:0009749 3 0.012
positive regulation of apoptotic signaling pathway GO:2001235 1 0.012
positive regulation of synapse assembly GO:0051965 1 0.012
neurotransmitter secretion GO:0007269 2 0.012
axon development GO:0061564 166 0.012
embryonic skeletal system development GO:0048706 97 0.012
growth GO:0040007 174 0.012
cellular component biogenesis GO:0044085 178 0.012
neuron projection development GO:0031175 180 0.012
neuron projection morphogenesis GO:0048812 161 0.012
cell morphogenesis involved in differentiation GO:0000904 195 0.012
apoptotic process GO:0006915 116 0.012
regulation of ion transmembrane transporter activity GO:0032412 2 0.012
macromolecular complex disassembly GO:0032984 1 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.012
sequestering of calcium ion GO:0051208 3 0.012
angiogenesis GO:0001525 158 0.012
phosphate containing compound metabolic process GO:0006796 108 0.012
lipid catabolic process GO:0016042 4 0.012
calcium ion transport into cytosol GO:0060402 3 0.012
positive regulation of nucleoside metabolic process GO:0045979 1 0.012
negative regulation of secretion GO:0051048 2 0.011
oocyte anterior posterior axis specification GO:0007314 4 0.011
multicellular organismal response to stress GO:0033555 2 0.011
interspecies interaction between organisms GO:0044419 4 0.011
regulation of dna replication GO:0006275 3 0.011
immune system development GO:0002520 191 0.011
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.011
determination of left right symmetry GO:0007368 179 0.011
macromolecule modification GO:0043412 111 0.011
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.011
phosphorus metabolic process GO:0006793 109 0.011
transcription from rna polymerase ii promoter GO:0006366 80 0.011
cellular lipid catabolic process GO:0044242 3 0.011
negative regulation of synapse assembly GO:0051964 2 0.011
positive regulation of dna metabolic process GO:0051054 1 0.011
cellular protein modification process GO:0006464 100 0.011
regulation of neurotransmitter secretion GO:0046928 1 0.011
positive regulation of nucleotide catabolic process GO:0030813 1 0.011
determination of bilateral symmetry GO:0009855 204 0.011
regulation of jak stat cascade GO:0046425 3 0.011
regulation of cell differentiation GO:0045595 142 0.011
transmembrane transport GO:0055085 120 0.011
locomotor rhythm GO:0045475 3 0.011
developmental programmed cell death GO:0010623 4 0.011
fatty acid catabolic process GO:0009062 1 0.011
positive regulation of gtpase activity GO:0043547 1 0.011
regulation of gtp catabolic process GO:0033124 2 0.011
actin filament polymerization GO:0030041 2 0.011
cytokinetic process GO:0032506 2 0.011
death GO:0016265 121 0.011
cell matrix adhesion GO:0007160 4 0.011
negative regulation of intracellular transport GO:0032387 3 0.011
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.011
peptidyl serine phosphorylation GO:0018105 1 0.011
negative regulation of defense response GO:0031348 2 0.011
actin polymerization or depolymerization GO:0008154 2 0.011
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.011
intracellular mrna localization GO:0008298 1 0.011
regulation of oocyte development GO:0060281 3 0.011
monocarboxylic acid catabolic process GO:0072329 3 0.011
peptide transport GO:0015833 1 0.011
primary neural tube formation GO:0014020 1 0.011
negative regulation of cytoplasmic transport GO:1903650 2 0.011
axonogenesis GO:0007409 152 0.011
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.011
protein polymerization GO:0051258 4 0.011
multi organism process GO:0051704 134 0.011
cellular localization GO:0051641 97 0.011
epithelial tube morphogenesis GO:0060562 148 0.011
peptidyl serine modification GO:0018209 2 0.011
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.011
negative regulation of cytokine production GO:0001818 1 0.011
positive regulation of gtp catabolic process GO:0033126 1 0.011
protein modification process GO:0036211 100 0.011
chemosensory behavior GO:0007635 1 0.011
carbohydrate homeostasis GO:0033500 1 0.010
regulation of protein ubiquitination GO:0031396 3 0.010
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.010
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.010
regulation of cell substrate adhesion GO:0010810 1 0.010
muscle cell differentiation GO:0042692 139 0.010
regulation of blood pressure GO:0008217 1 0.010
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.010
regulation of protein import into nucleus GO:0042306 2 0.010
protein stabilization GO:0050821 2 0.010
cellular response to molecule of bacterial origin GO:0071219 3 0.010
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.010
tube closure GO:0060606 1 0.010
regulation of tube size GO:0035150 2 0.010
response to uv GO:0009411 3 0.010
response to abiotic stimulus GO:0009628 122 0.010
toll like receptor signaling pathway GO:0002224 4 0.010
pole plasm assembly GO:0007315 4 0.010
negative regulation of nuclear division GO:0051784 3 0.010
cellular response to oxygen levels GO:0071453 1 0.010
negative regulation of secretion by cell GO:1903531 2 0.010
intracellular signal transduction GO:0035556 85 0.010
organism emergence from protective structure GO:0071684 4 0.010
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.010
nuclear export GO:0051168 1 0.010
cell death GO:0008219 121 0.010
cellular response to organic substance GO:0071310 105 0.010
sensory perception of pain GO:0019233 1 0.010
response to endogenous stimulus GO:0009719 83 0.010

tha1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.043
nervous system disease DOID:863 0 0.021
musculoskeletal system disease DOID:17 0 0.018
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
organ system cancer DOID:0050686 0 0.014
disease of metabolism DOID:0014667 0 0.013
bone disease DOID:0080001 0 0.011
connective tissue disease DOID:65 0 0.011