Danio rerio

12 known processes

aqp1a.2

aquaporin 1a, tandem duplicate 2

aqp1a.2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of biological quality GO:0065008 263 0.079
transport GO:0006810 220 0.061
signal transduction GO:0007165 455 0.051
larval development GO:0002164 2 0.051
aging GO:0007568 2 0.048
head development GO:0060322 303 0.047
cell surface receptor signaling pathway GO:0007166 325 0.045
positive regulation of transport GO:0051050 2 0.042
maintenance of location GO:0051235 4 0.041
g protein coupled receptor signaling pathway GO:0007186 74 0.038
cellular nitrogen compound metabolic process GO:0034641 290 0.036
negative regulation of protein phosphorylation GO:0001933 4 0.036
central nervous system development GO:0007417 387 0.035
female gonad development GO:0008585 4 0.035
brain development GO:0007420 293 0.035
cognition GO:0050890 1 0.035
single organism localization GO:1902578 225 0.034
negative regulation of biological process GO:0048519 304 0.034
regulation of hormone secretion GO:0046883 2 0.034
regulation of establishment of protein localization GO:0070201 4 0.033
system process GO:0003008 185 0.032
regulation of primary metabolic process GO:0080090 311 0.032
single organism transport GO:0044765 206 0.032
regulation of multicellular organismal process GO:0051239 277 0.032
regulation of cytokine production GO:0001817 3 0.032
adult behavior GO:0030534 2 0.032
negative regulation of secretion GO:0051048 2 0.032
leukocyte proliferation GO:0070661 1 0.032
hormone transport GO:0009914 2 0.032
female sex differentiation GO:0046660 4 0.031
regulation of reproductive process GO:2000241 4 0.031
response to carbohydrate GO:0009743 3 0.031
phagocytosis GO:0006909 3 0.030
regulation of signaling GO:0023051 235 0.030
regulation of protein transport GO:0051223 3 0.030
regulation of gene expression GO:0010468 265 0.029
regulation of cellular metabolic process GO:0031323 320 0.029
generation of neurons GO:0048699 385 0.029
regulation of signal transduction GO:0009966 225 0.028
multicellular organism growth GO:0035264 4 0.028
heterocycle metabolic process GO:0046483 290 0.028
regionalization GO:0003002 274 0.028
establishment of localization GO:0051234 244 0.028
tube morphogenesis GO:0035239 349 0.028
lipid storage GO:0019915 1 0.028
regulation of response to stimulus GO:0048583 269 0.028
cellular macromolecule metabolic process GO:0044260 391 0.028
regulation of inflammatory response GO:0050727 2 0.027
response to chemical GO:0042221 320 0.027
response to drug GO:0042493 3 0.027
meiotic cell cycle process GO:1903046 3 0.027
regulation of nitrogen compound metabolic process GO:0051171 251 0.026
single organism metabolic process GO:0044710 217 0.026
negative regulation of secretion by cell GO:1903531 2 0.026
regulation of metal ion transport GO:0010959 4 0.026
regulation of multicellular organism growth GO:0040014 4 0.026
organic cyclic compound metabolic process GO:1901360 301 0.026
stem cell maintenance GO:0019827 4 0.026
negative regulation of protein kinase activity GO:0006469 4 0.026
cellular aromatic compound metabolic process GO:0006725 295 0.026
response to hexose GO:0009746 3 0.025
glucose homeostasis GO:0042593 1 0.025
hormone secretion GO:0046879 2 0.025
response to stress GO:0006950 263 0.025
amine metabolic process GO:0009308 2 0.025
regulation of cell communication GO:0010646 232 0.025
positive regulation of biological process GO:0048518 253 0.025
response to monosaccharide GO:0034284 3 0.025
neuron differentiation GO:0030182 353 0.025
morphogenesis of an epithelium GO:0002009 333 0.025
positive regulation of cellular component biogenesis GO:0044089 3 0.025
regulation of multicellular organismal development GO:2000026 223 0.024
organonitrogen compound metabolic process GO:1901564 74 0.024
small molecule metabolic process GO:0044281 77 0.024
development of primary female sexual characteristics GO:0046545 4 0.024
organic substance biosynthetic process GO:1901576 289 0.024
nitrogen compound metabolic process GO:0006807 319 0.024
response to organic substance GO:0010033 153 0.023
i kappab kinase nf kappab signaling GO:0007249 4 0.023
cell projection morphogenesis GO:0048858 244 0.023
regulation of macromolecule metabolic process GO:0060255 317 0.023
determination of bilateral symmetry GO:0009855 204 0.023
nitric oxide metabolic process GO:0046209 2 0.023
regulation of cellular amine metabolic process GO:0033238 0 0.023
response to glucose GO:0009749 3 0.023
peptide transport GO:0015833 1 0.022
response to external stimulus GO:0009605 264 0.022
regulation of cell activation GO:0050865 1 0.022
negative regulation of kinase activity GO:0033673 4 0.022
regulation of tube size GO:0035150 2 0.022
nucleobase containing compound metabolic process GO:0006139 274 0.022
mononuclear cell proliferation GO:0032943 1 0.022
cellular component morphogenesis GO:0032989 336 0.021
positive regulation of cellular process GO:0048522 201 0.021
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.021
protein acetylation GO:0006473 2 0.021
cellular ketone metabolic process GO:0042180 11 0.021
oxoacid metabolic process GO:0043436 31 0.021
nuclear transport GO:0051169 4 0.021
positive regulation of cell activation GO:0050867 1 0.021
protein secretion GO:0009306 1 0.021
organic acid metabolic process GO:0006082 31 0.021
cellular amine metabolic process GO:0044106 2 0.021
regulation of developmental process GO:0050793 247 0.020
modification dependent macromolecule catabolic process GO:0043632 3 0.020
biosynthetic process GO:0009058 294 0.020
positive regulation of cellular catabolic process GO:0031331 3 0.020
endocrine process GO:0050886 2 0.020
immune system process GO:0002376 241 0.020
regulation of cytoplasmic transport GO:1903649 4 0.020
ovulation cycle GO:0042698 2 0.020
regulation of cellular ketone metabolic process GO:0010565 7 0.020
positive regulation of secretion by cell GO:1903532 1 0.020
cellular biosynthetic process GO:0044249 286 0.020
regulation of metabolic process GO:0019222 359 0.020
negative regulation of cellular process GO:0048523 283 0.020
regulation of systemic arterial blood pressure GO:0003073 1 0.020
cellular response to external stimulus GO:0071496 2 0.019
positive regulation of secretion GO:0051047 1 0.019
peptidyl lysine acetylation GO:0018394 2 0.019
positive regulation of cytokine production GO:0001819 2 0.019
rna metabolic process GO:0016070 219 0.019
regulation of blood vessel size GO:0050880 2 0.019
carbohydrate homeostasis GO:0033500 1 0.019
cellular component movement GO:0006928 335 0.019
embryonic organ development GO:0048568 381 0.019
chordate embryonic development GO:0043009 271 0.019
regulation of protein complex assembly GO:0043254 3 0.019
ubiquitin dependent protein catabolic process GO:0006511 3 0.019
cellular nitrogen compound biosynthetic process GO:0044271 218 0.019
cell migration GO:0016477 237 0.019
vasculature development GO:0001944 278 0.019
regulation of cellular biosynthetic process GO:0031326 245 0.019
neurotransmitter transport GO:0006836 2 0.018
positive regulation of catabolic process GO:0009896 4 0.018
transmembrane transport GO:0055085 120 0.018
regulation of endocrine process GO:0044060 2 0.018
regulation of synapse assembly GO:0051963 3 0.018
autophagy GO:0006914 4 0.018
lipid catabolic process GO:0016042 4 0.018
establishment of protein localization to organelle GO:0072594 4 0.018
carboxylic acid metabolic process GO:0019752 22 0.018
regulation of cellular amino acid metabolic process GO:0006521 0 0.018
aromatic compound biosynthetic process GO:0019438 217 0.018
positive regulation of cell cycle GO:0045787 3 0.018
camera type eye development GO:0043010 222 0.018
cell part morphogenesis GO:0032990 246 0.018
protein localization to nucleus GO:0034504 3 0.018
regulation of blood pressure GO:0008217 1 0.018
gtp metabolic process GO:0046039 4 0.017
lymphocyte proliferation GO:0046651 1 0.017
synaptic growth at neuromuscular junction GO:0051124 2 0.017
cell morphogenesis GO:0000902 289 0.017
production of molecular mediator of immune response GO:0002440 2 0.017
guanosine containing compound metabolic process GO:1901068 4 0.017
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.017
regulation of localization GO:0032879 104 0.017
regulation of synapse organization GO:0050807 3 0.017
rna localization GO:0006403 4 0.017
cellular response to biotic stimulus GO:0071216 3 0.017
immune system development GO:0002520 191 0.017
cellular amide metabolic process GO:0043603 4 0.017
nucleocytoplasmic transport GO:0006913 4 0.017
gene expression GO:0010467 252 0.017
anterior posterior pattern specification GO:0009952 152 0.017
macromolecule biosynthetic process GO:0009059 227 0.017
regulation of reactive oxygen species metabolic process GO:2000377 2 0.017
gtp catabolic process GO:0006184 2 0.017
negative regulation of defense response GO:0031348 2 0.016
internal protein amino acid acetylation GO:0006475 2 0.016
digestive system development GO:0055123 289 0.016
cell motility GO:0048870 244 0.016
protein acylation GO:0043543 3 0.016
cellular response to nutrient levels GO:0031669 2 0.016
cellular protein catabolic process GO:0044257 4 0.016
regulation of meiotic cell cycle GO:0051445 1 0.016
phagocytosis engulfment GO:0006911 1 0.016
ovulation cycle process GO:0022602 2 0.016
nucleobase containing compound biosynthetic process GO:0034654 205 0.016
protein targeting to nucleus GO:0044744 3 0.016
meiotic nuclear division GO:0007126 4 0.016
endocrine hormone secretion GO:0060986 2 0.016
ion transmembrane transport GO:0034220 91 0.016
regulation of protein catabolic process GO:0042176 1 0.016
lipid homeostasis GO:0055088 3 0.016
determination of left right symmetry GO:0007368 179 0.016
protein metabolic process GO:0019538 183 0.016
sensory perception of chemical stimulus GO:0007606 3 0.016
protein heterooligomerization GO:0051291 1 0.015
cellular macromolecule biosynthetic process GO:0034645 224 0.015
compound eye development GO:0048749 2 0.015
cytokinesis GO:0000910 3 0.015
meiotic chromosome segregation GO:0045132 3 0.015
single organism organelle organization GO:1902589 199 0.015
digestive tract development GO:0048565 265 0.015
response to biotic stimulus GO:0009607 97 0.015
response to amine GO:0014075 1 0.015
blood vessel development GO:0001568 246 0.015
reactive oxygen species biosynthetic process GO:1903409 1 0.015
positive regulation of cellular amine metabolic process GO:0033240 0 0.015
nuclear import GO:0051170 3 0.015
regulation of autophagy GO:0010506 3 0.015
sensory organ development GO:0007423 393 0.015
ribonucleoside monophosphate catabolic process GO:0009158 4 0.015
positive regulation of inflammatory response GO:0050729 1 0.015
embryo development ending in birth or egg hatching GO:0009792 271 0.015
negative regulation of hormone secretion GO:0046888 2 0.015
positive regulation of immune effector process GO:0002699 3 0.015
locomotion GO:0040011 313 0.015
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.015
regulation of protein localization to nucleus GO:1900180 2 0.015
mitochondrion organization GO:0007005 4 0.015
regulation of muscle contraction GO:0006937 3 0.015
chemosensory behavior GO:0007635 1 0.015
cellular component biogenesis GO:0044085 178 0.015
cellular component disassembly GO:0022411 1 0.015
regulation of production of molecular mediator of immune response GO:0002700 1 0.015
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.015
regulation of intracellular protein transport GO:0033157 3 0.015
regulation of biosynthetic process GO:0009889 250 0.014
cellular component assembly GO:0022607 170 0.014
protein import GO:0017038 3 0.014
regulation of protein import into nucleus GO:0042306 2 0.014
exocytosis GO:0006887 1 0.014
single organism nuclear import GO:1902593 3 0.014
modification dependent protein catabolic process GO:0019941 3 0.014
blood vessel morphogenesis GO:0048514 216 0.014
eye development GO:0001654 277 0.014
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.014
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.014
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.014
adherens junction organization GO:0034332 4 0.014
sodium ion transmembrane transport GO:0035725 21 0.014
regulation of nucleocytoplasmic transport GO:0046822 2 0.014
heterocycle biosynthetic process GO:0018130 215 0.014
angiogenesis GO:0001525 158 0.014
muscle structure development GO:0061061 196 0.014
regulation of neurotransmitter transport GO:0051588 1 0.014
internal peptidyl lysine acetylation GO:0018393 2 0.014
cellular response to chemical stimulus GO:0070887 157 0.014
localization of cell GO:0051674 244 0.014
protein polymerization GO:0051258 4 0.014
regulation of system process GO:0044057 40 0.014
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.014
rna biosynthetic process GO:0032774 181 0.014
gastrulation GO:0007369 208 0.014
cellular response to starvation GO:0009267 1 0.014
heart development GO:0007507 313 0.014
antimicrobial humoral response GO:0019730 2 0.014
regulation of neural precursor cell proliferation GO:2000177 3 0.014
organelle organization GO:0006996 227 0.014
neuron development GO:0048666 262 0.014
dorsal ventral pattern formation GO:0009953 125 0.014
embryonic organ morphogenesis GO:0048562 274 0.014
regulation of calcium ion transport GO:0051924 2 0.014
cell projection organization GO:0030030 284 0.013
cellular response to organic substance GO:0071310 105 0.013
cellular response to extracellular stimulus GO:0031668 2 0.013
organic cyclic compound biosynthetic process GO:1901362 223 0.013
nucleoside monophosphate catabolic process GO:0009125 4 0.013
guanosine containing compound catabolic process GO:1901069 2 0.013
complement activation GO:0006956 3 0.013
intracellular mrna localization GO:0008298 1 0.013
negative regulation of catabolic process GO:0009895 3 0.013
specification of symmetry GO:0009799 204 0.013
intracellular signal transduction GO:0035556 85 0.013
somitogenesis GO:0001756 87 0.013
protein localization to plasma membrane GO:0072659 1 0.013
regulation of binding GO:0051098 3 0.013
negative regulation of protein complex assembly GO:0031333 1 0.013
positive regulation of cytoskeleton organization GO:0051495 3 0.013
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.013
nucleic acid templated transcription GO:0097659 181 0.013
digestive tract morphogenesis GO:0048546 231 0.013
cell morphogenesis involved in differentiation GO:0000904 195 0.013
cellular response to molecule of bacterial origin GO:0071219 3 0.013
regulation of macromolecule biosynthetic process GO:0010556 225 0.013
proteasomal protein catabolic process GO:0010498 2 0.013
somite development GO:0061053 96 0.013
small molecule catabolic process GO:0044282 3 0.013
regulation of nucleoside metabolic process GO:0009118 2 0.013
response to other organism GO:0051707 97 0.013
regulation of nucleotide catabolic process GO:0030811 2 0.013
homeostatic process GO:0042592 142 0.013
neurotransmitter secretion GO:0007269 2 0.013
negative regulation of mapk cascade GO:0043409 4 0.013
cellular amino acid metabolic process GO:0006520 7 0.013
transcription dna templated GO:0006351 181 0.012
determination of heart left right asymmetry GO:0061371 117 0.012
nitric oxide biosynthetic process GO:0006809 2 0.012
regulation of gtpase activity GO:0043087 2 0.012
cellular localization GO:0051641 97 0.012
regulation of purine nucleotide catabolic process GO:0033121 2 0.012
protein homooligomerization GO:0051260 3 0.012
negative regulation of cytokine production GO:0001818 1 0.012
neuron projection morphogenesis GO:0048812 161 0.012
positive regulation of reproductive process GO:2000243 2 0.012
transcription from rna polymerase ii promoter GO:0006366 80 0.012
secondary metabolic process GO:0019748 3 0.012
regulation of neurotransmitter secretion GO:0046928 1 0.012
regulation of synaptic plasticity GO:0048167 1 0.012
negative regulation of chromosome organization GO:2001251 1 0.012
peptide metabolic process GO:0006518 1 0.012
positive regulation of dna metabolic process GO:0051054 1 0.012
purine nucleoside monophosphate catabolic process GO:0009128 4 0.012
stem cell proliferation GO:0072089 4 0.012
regulation of sequestering of calcium ion GO:0051282 4 0.012
cellular carbohydrate metabolic process GO:0044262 4 0.012
regulation of response to extracellular stimulus GO:0032104 1 0.012
somatic muscle development GO:0007525 4 0.012
translational initiation GO:0006413 3 0.012
actin polymerization or depolymerization GO:0008154 2 0.012
response to external biotic stimulus GO:0043207 97 0.012
rna 3 end processing GO:0031123 2 0.012
macromolecular complex disassembly GO:0032984 1 0.012
b cell mediated immunity GO:0019724 3 0.012
response to abiotic stimulus GO:0009628 122 0.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.012
negative regulation of reproductive process GO:2000242 3 0.012
positive regulation of nucleoside metabolic process GO:0045979 1 0.012
positive regulation of chromatin modification GO:1903310 1 0.012
cellular protein modification process GO:0006464 100 0.012
positive regulation of map kinase activity GO:0043406 3 0.012
atp catabolic process GO:0006200 4 0.012
negative regulation of dna metabolic process GO:0051053 4 0.011
b cell activation GO:0042113 2 0.011
single organism biosynthetic process GO:0044711 71 0.011
segmentation GO:0035282 97 0.011
sensory organ morphogenesis GO:0090596 200 0.011
tissue remodeling GO:0048771 4 0.011
organelle assembly GO:0070925 110 0.011
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.011
hemopoiesis GO:0030097 183 0.011
cytosolic calcium ion transport GO:0060401 3 0.011
reactive nitrogen species metabolic process GO:2001057 0 0.011
cell death GO:0008219 121 0.011
activation of mapk activity GO:0000187 3 0.011
fatty acid transport GO:0015908 1 0.011
heart morphogenesis GO:0003007 156 0.011
golgi vesicle transport GO:0048193 3 0.011
positive regulation of epithelial cell differentiation GO:0030858 2 0.011
regulation of transmembrane transporter activity GO:0022898 2 0.011
response to corticosteroid GO:0031960 1 0.011
monovalent inorganic cation transport GO:0015672 42 0.011
regulation of oocyte development GO:0060281 3 0.011
membrane invagination GO:0010324 1 0.011
developmental growth GO:0048589 166 0.011
chemical homeostasis GO:0048878 49 0.011
response to alkaloid GO:0043279 2 0.011
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.011
retina development in camera type eye GO:0060041 146 0.011
actin filament polymerization GO:0030041 2 0.011
protein complex disassembly GO:0043241 1 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.011
neurological system process GO:0050877 62 0.011
regulation of rna metabolic process GO:0051252 224 0.011
response to wounding GO:0009611 116 0.011
single fertilization GO:0007338 3 0.011
regulation of transporter activity GO:0032409 2 0.011
positive regulation of protein complex assembly GO:0031334 2 0.011
negative regulation of cytoplasmic transport GO:1903650 2 0.011
regulation of ion transmembrane transporter activity GO:0032412 2 0.011
embryonic heart tube development GO:0035050 133 0.011
sequestering of calcium ion GO:0051208 3 0.011
growth GO:0040007 174 0.011
calcium ion transport into cytosol GO:0060402 3 0.011
positive regulation of chromosome organization GO:2001252 1 0.011
renal system development GO:0072001 94 0.011
regulation of cellular protein catabolic process GO:1903362 1 0.011
response to endogenous stimulus GO:0009719 83 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.010
positive regulation of cell division GO:0051781 2 0.010
protein import into nucleus GO:0006606 3 0.010
establishment of localization in cell GO:0051649 77 0.010
protein stabilization GO:0050821 2 0.010
interspecies interaction between organisms GO:0044419 4 0.010
carbohydrate biosynthetic process GO:0016051 1 0.010
death GO:0016265 121 0.010
cytoskeleton dependent cytokinesis GO:0061640 3 0.010
nuclear export GO:0051168 1 0.010
immunoglobulin mediated immune response GO:0016064 3 0.010
organic substance transport GO:0071702 58 0.010
nucleic acid metabolic process GO:0090304 244 0.010
ion transport GO:0006811 114 0.010
meiosis i GO:0007127 1 0.010
regulation of transcription dna templated GO:0006355 213 0.010
amino acid transport GO:0006865 2 0.010
organic acid catabolic process GO:0016054 3 0.010
sprouting angiogenesis GO:0002040 53 0.010
post embryonic organ development GO:0048569 4 0.010
synaptic vesicle transport GO:0048489 1 0.010
regulation of dna recombination GO:0000018 2 0.010
epithelial tube morphogenesis GO:0060562 148 0.010
morphogenesis of an epithelial sheet GO:0002011 49 0.010
carbohydrate derivative biosynthetic process GO:1901137 43 0.010
negative regulation of multi organism process GO:0043901 3 0.010
spermatid differentiation GO:0048515 2 0.010
heart process GO:0003015 71 0.010
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.010

aqp1a.2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.044
musculoskeletal system disease DOID:17 0 0.020
nervous system disease DOID:863 0 0.019
disease of metabolism DOID:0014667 0 0.014
disease of cellular proliferation DOID:14566 0 0.013
cancer DOID:162 0 0.012
muscular disease DOID:0080000 0 0.012
muscle tissue disease DOID:66 0 0.011
organ system cancer DOID:0050686 0 0.011
cardiovascular system disease DOID:1287 0 0.010