Danio rerio

53 known processes

fstl1a

follistatin-like 1a

(Aliases: zgc:110703,wu:fc75h02,fstl1)

fstl1a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.789
aging GO:0007568 2 0.259
embryonic limb morphogenesis GO:0030326 2 0.186
embryonic neurocranium morphogenesis GO:0048702 15 0.152
biosynthetic process GO:0009058 294 0.150
eye development GO:0001654 277 0.083
positive regulation of translation GO:0045727 1 0.081
proximal distal pattern formation GO:0009954 1 0.079
chondrocyte development GO:0002063 4 0.076
response to vitamin GO:0033273 3 0.075
central nervous system development GO:0007417 387 0.072
Zebrafish
regulation of mrna splicing via spliceosome GO:0048024 3 0.069
response to biotic stimulus GO:0009607 97 0.067
response to external biotic stimulus GO:0043207 97 0.067
establishment of localization GO:0051234 244 0.064
nuclear division GO:0000280 23 0.063
positive regulation of muscle tissue development GO:1901863 1 0.062
negative regulation of signal transduction in absence of ligand GO:1901099 1 0.062
carbohydrate derivative metabolic process GO:1901135 61 0.060
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.058
endocardial cushion formation GO:0003272 2 0.056
segmentation GO:0035282 97 0.054
embryonic skeletal system morphogenesis GO:0048704 93 0.052
Zebrafish
nucleobase containing compound metabolic process GO:0006139 274 0.052
single organism localization GO:1902578 225 0.051
organelle fission GO:0048285 23 0.047
cartilage development GO:0051216 96 0.047
odontogenesis of dentin containing tooth GO:0042475 1 0.045
regionalization GO:0003002 274 0.045
Zebrafish
cell cycle GO:0007049 93 0.044
response to vitamin b3 GO:0033552 2 0.044
nephron development GO:0072006 31 0.043
response to other organism GO:0051707 97 0.043
connective tissue development GO:0061448 99 0.043
wound healing GO:0042060 90 0.041
kidney vasculature development GO:0061440 2 0.041
brain development GO:0007420 293 0.040
Zebrafish
response to glucocorticoid GO:0051384 1 0.039
appendage development GO:0048736 80 0.039
startle response GO:0001964 4 0.038
negative regulation of nervous system development GO:0051961 22 0.038
response to wounding GO:0009611 116 0.038
non canonical wnt signaling pathway GO:0035567 13 0.038
positive regulation of transport GO:0051050 2 0.037
negative regulation of chemotaxis GO:0050922 4 0.037
retinoic acid receptor signaling pathway GO:0048384 16 0.035
regulation of cell activation GO:0050865 1 0.034
embryo development ending in birth or egg hatching GO:0009792 271 0.033
Zebrafish Worm
regulation of metabolic process GO:0019222 359 0.033
negative regulation of axon extension involved in axon guidance GO:0048843 1 0.033
response to stress GO:0006950 263 0.031
Mouse
lipid storage GO:0019915 1 0.031
cell migration involved in gastrulation GO:0042074 79 0.031
response to nutrient GO:0007584 3 0.031
dorsal ventral pattern formation GO:0009953 125 0.031
Zebrafish
single fertilization GO:0007338 3 0.030
embryonic skeletal joint morphogenesis GO:0060272 3 0.030
cellular response to extracellular stimulus GO:0031668 2 0.030
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 1 0.029
regulation of wound healing GO:0061041 2 0.029
sensory organ morphogenesis GO:0090596 200 0.029
Zebrafish
multi organism process GO:0051704 134 0.028
negative regulation of cell proliferation GO:0008285 8 0.028
embryonic organ development GO:0048568 381 0.028
cellular amino acid metabolic process GO:0006520 7 0.028
protein metabolic process GO:0019538 183 0.027
i kappab kinase nf kappab signaling GO:0007249 4 0.027
negative regulation of cellular process GO:0048523 283 0.027
positive regulation of striated muscle tissue development GO:0045844 1 0.027
g protein coupled receptor signaling pathway GO:0007186 74 0.027
somitogenesis GO:0001756 87 0.026
macromolecule biosynthetic process GO:0009059 227 0.026
pectoral fin morphogenesis GO:0035138 29 0.026
positive regulation of gastrulation GO:2000543 2 0.024
stem cell differentiation GO:0048863 117 0.024
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.024
endochondral bone growth GO:0003416 2 0.023
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.023
defense response GO:0006952 47 0.023
regulation of transcription dna templated GO:0006355 213 0.023
embryonic skeletal joint development GO:0072498 3 0.023
regulation of organ growth GO:0046620 3 0.023
response to corticosteroid GO:0031960 1 0.023
regulation of catenin import into nucleus GO:0035412 2 0.023
positive regulation of cellular component biogenesis GO:0044089 3 0.023
nucleocytoplasmic transport GO:0006913 4 0.022
muscle cell differentiation GO:0042692 139 0.022
single organism transport GO:0044765 206 0.022
maintenance of location GO:0051235 4 0.022
regulation of cellular biosynthetic process GO:0031326 245 0.022
organic acid metabolic process GO:0006082 31 0.022
meiotic nuclear division GO:0007126 4 0.022
embryonic skeletal system development GO:0048706 97 0.021
Zebrafish
radial glial cell differentiation GO:0060019 2 0.020
growth plate cartilage development GO:0003417 2 0.020
negative regulation of cell differentiation GO:0045596 46 0.020
patterning of blood vessels GO:0001569 15 0.020
regulation of cellular amino acid metabolic process GO:0006521 0 0.020
chordate embryonic development GO:0043009 271 0.020
Zebrafish
striated muscle cell differentiation GO:0051146 129 0.020
regulation of reproductive process GO:2000241 4 0.020
response to external stimulus GO:0009605 264 0.020
Mouse
kidney development GO:0001822 92 0.019
oocyte maturation GO:0001556 4 0.019
positive regulation of wound healing GO:0090303 1 0.019
negative regulation of multicellular organismal process GO:0051241 69 0.019
embryonic foregut morphogenesis GO:0048617 1 0.019
single organism nuclear import GO:1902593 3 0.019
response to uv GO:0009411 3 0.019
somite development GO:0061053 96 0.019
response to hormone GO:0009725 48 0.018
glomerulus vasculature development GO:0072012 2 0.018
transport GO:0006810 220 0.018
protein targeting to nucleus GO:0044744 3 0.018
sexual reproduction GO:0019953 36 0.018
regulation of nitrogen compound metabolic process GO:0051171 251 0.018
regulation of anatomical structure size GO:0090066 33 0.018
embryonic cranial skeleton morphogenesis GO:0048701 90 0.018
Zebrafish
renal system vasculature development GO:0061437 2 0.018
branching morphogenesis of an epithelial tube GO:0048754 15 0.018
smooth muscle tissue development GO:0048745 1 0.018
cellular protein catabolic process GO:0044257 4 0.018
regulation of collateral sprouting in absence of injury GO:0048696 4 0.018
female gonad development GO:0008585 4 0.017
response to organic substance GO:0010033 153 0.017
negative regulation of muscle tissue development GO:1901862 2 0.017
optic placode formation involved in camera type eye formation GO:0046619 3 0.017
appendage morphogenesis GO:0035107 56 0.017
signal transduction in absence of ligand GO:0038034 1 0.017
formation of primary germ layer GO:0001704 62 0.017
reproduction GO:0000003 40 0.017
Worm
signal transduction GO:0007165 455 0.017
regulation of cytokine production GO:0001817 3 0.016
positive regulation of metabolic process GO:0009893 108 0.016
regulation of cardiac muscle tissue development GO:0055024 1 0.016
facial nerve development GO:0021561 3 0.016
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.016
eye field cell fate commitment involved in camera type eye formation GO:0060898 3 0.016
mrna metabolic process GO:0016071 20 0.016
embryonic organ morphogenesis GO:0048562 274 0.016
Zebrafish
negative regulation of biological process GO:0048519 304 0.016
female sex differentiation GO:0046660 4 0.016
negative regulation of nuclear division GO:0051784 3 0.016
cellular component movement GO:0006928 335 0.016
developmental programmed cell death GO:0010623 4 0.015
glomerulus development GO:0032835 27 0.015
small molecule metabolic process GO:0044281 77 0.015
limb morphogenesis GO:0035108 7 0.015
cellular response to external stimulus GO:0071496 2 0.015
establishment of protein localization to organelle GO:0072594 4 0.015
preganglionic parasympathetic nervous system development GO:0021783 6 0.015
limb bud formation GO:0060174 2 0.015
protein polymerization GO:0051258 4 0.014
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.014
response to steroid hormone GO:0048545 35 0.014
regulation of primary metabolic process GO:0080090 311 0.014
morphogenesis of a branching structure GO:0001763 21 0.014
nuclear transport GO:0051169 4 0.014
cellular response to estradiol stimulus GO:0071392 1 0.014
facial nerve morphogenesis GO:0021610 1 0.014
striated muscle tissue development GO:0014706 110 0.014
cytoskeleton dependent cytokinesis GO:0061640 3 0.014
neuron development GO:0048666 262 0.014
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.014
regulation of meiotic cell cycle GO:0051445 1 0.014
negative regulation of epithelial cell differentiation GO:0030857 2 0.014
cellular nitrogen compound metabolic process GO:0034641 290 0.014
regulation of epidermis development GO:0045682 2 0.014
heterocycle metabolic process GO:0046483 290 0.014
regulation of protein catabolic process GO:0042176 1 0.014
regulation of protein ubiquitination GO:0031396 3 0.013
phagocytosis GO:0006909 3 0.013
muscle structure development GO:0061061 196 0.013
organonitrogen compound metabolic process GO:1901564 74 0.013
leukocyte proliferation GO:0070661 1 0.013
heart looping GO:0001947 94 0.013
small molecule catabolic process GO:0044282 3 0.013
multicellular organismal reproductive process GO:0048609 35 0.013
extracellular matrix organization GO:0030198 27 0.013
developmental process involved in reproduction GO:0003006 27 0.013
lymphocyte proliferation GO:0046651 1 0.013
negative regulation of endodermal cell differentiation GO:1903225 8 0.013
specification of symmetry GO:0009799 204 0.013
Zebrafish
negative regulation of mitosis GO:0045839 3 0.013
positive regulation of cellular metabolic process GO:0031325 94 0.013
regulation of multicellular organismal process GO:0051239 277 0.012
regulation of transcription from rna polymerase iii promoter GO:0006359 1 0.012
cellular ketone metabolic process GO:0042180 11 0.012
negative regulation of leukocyte differentiation GO:1902106 1 0.012
cell cycle g1 s phase transition GO:0044843 1 0.012
cellular component assembly GO:0022607 170 0.012
transcription from rna polymerase ii promoter GO:0006366 80 0.012
striated muscle cell proliferation GO:0014855 7 0.012
bone mineralization GO:0030282 9 0.012
modification dependent protein catabolic process GO:0019941 3 0.012
protein import GO:0017038 3 0.012
mesenchymal cell proliferation GO:0010463 1 0.012
nephron tubule morphogenesis GO:0072078 1 0.012
cellular response to organic substance GO:0071310 105 0.012
regulation of microtubule cytoskeleton organization GO:0070507 3 0.012
apoptotic process involved in development GO:1902742 2 0.012
somatic muscle development GO:0007525 4 0.012
cellular response to nutrient levels GO:0031669 2 0.012
embryonic digestive tract morphogenesis GO:0048557 3 0.012
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.012
embryonic heart tube formation GO:0003144 1 0.012
cellular response to chemical stimulus GO:0070887 157 0.012
ventricular cardiac muscle cell differentiation GO:0055012 6 0.012
transcription from rna polymerase iii promoter GO:0006383 1 0.011
positive regulation of muscle organ development GO:0048636 1 0.011
cardiac chamber formation GO:0003207 4 0.011
b cell activation GO:0042113 2 0.011
regulation of localization GO:0032879 104 0.011
regulation of biosynthetic process GO:0009889 250 0.011
embryonic appendage morphogenesis GO:0035113 30 0.011
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.011
cell proliferation GO:0008283 80 0.011
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 22 0.011
cellular localization GO:0051641 97 0.011
positive regulation of cysteine type endopeptidase activity GO:2001056 10 0.011
cellular protein metabolic process GO:0044267 129 0.011
cellular response to hormone stimulus GO:0032870 39 0.011
cellular aromatic compound metabolic process GO:0006725 295 0.011
organelle organization GO:0006996 227 0.011
response to lipid GO:0033993 60 0.011
rna stabilization GO:0043489 4 0.011
regulation of cellular amine metabolic process GO:0033238 0 0.011
regulation of rna biosynthetic process GO:2001141 213 0.011
multicellular organism growth GO:0035264 4 0.011
regulation of mrna processing GO:0050684 3 0.011
amine metabolic process GO:0009308 2 0.011
negative regulation of oocyte development GO:0060283 2 0.011
trigeminal nerve development GO:0021559 3 0.011
mononuclear cell proliferation GO:0032943 1 0.011
positive regulation of cgmp biosynthetic process GO:0030828 6 0.011
localization of cell GO:0051674 244 0.010
cellular nitrogen compound biosynthetic process GO:0044271 218 0.010
response to organic cyclic compound GO:0014070 51 0.010
positive regulation of biosynthetic process GO:0009891 68 0.010
cellular protein complex assembly GO:0043623 19 0.010
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.010
auditory receptor cell fate commitment GO:0009912 4 0.010
cell migration GO:0016477 237 0.010
regulation of rna metabolic process GO:0051252 224 0.010

fstl1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
bone development disease DOID:0080006 0 0.074
bone disease DOID:0080001 0 0.074
disease of anatomical entity DOID:7 0 0.074
musculoskeletal system disease DOID:17 0 0.074
connective tissue disease DOID:65 0 0.074
disease of metabolism DOID:0014667 0 0.052
osteochondrodysplasia DOID:2256 0 0.035
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014