Danio rerio

0 known processes

pdip5

protein disulfide isomerase-related protein (provisional)

(Aliases: wu:fc09e09,pdi-p5,wu:fb51h08)

pdip5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular response to topologically incorrect protein GO:0035967 2 0.926
Worm
endoplasmic reticulum unfolded protein response GO:0030968 2 0.531
Worm
larval development GO:0002164 2 0.501
Worm
er nucleus signaling pathway GO:0006984 2 0.444
Worm
cellular response to unfolded protein GO:0034620 2 0.344
Worm
regulation of response to stimulus GO:0048583 269 0.253
locomotion GO:0040011 313 0.228
Worm
sensory organ development GO:0007423 393 0.223
protein n linked glycosylation GO:0006487 1 0.211
cellular component assembly GO:0022607 170 0.203
response to topologically incorrect protein GO:0035966 2 0.197
Worm
signal transduction GO:0007165 455 0.191
Worm
cell morphogenesis GO:0000902 289 0.183
multicellular organismal reproductive process GO:0048609 35 0.183
cell surface receptor signaling pathway GO:0007166 325 0.175
aging GO:0007568 2 0.173
response to endoplasmic reticulum stress GO:0034976 6 0.167
Worm
cellular response to chemical stimulus GO:0070887 157 0.134
Worm
cell motility GO:0048870 244 0.127
response to temperature stimulus GO:0009266 15 0.120
cellular response to organic substance GO:0071310 105 0.118
Worm
multicellular organism reproduction GO:0032504 35 0.116
ameboidal type cell migration GO:0001667 143 0.107
determination of bilateral symmetry GO:0009855 204 0.105
response to organic substance GO:0010033 153 0.105
Worm
cellular protein metabolic process GO:0044267 129 0.105
response to chemical GO:0042221 320 0.100
Worm
response to stress GO:0006950 263 0.097
Worm
cellular component morphogenesis GO:0032989 336 0.097
tube morphogenesis GO:0035239 349 0.082
digestive system development GO:0055123 289 0.081
specification of symmetry GO:0009799 204 0.080
digestive tract morphogenesis GO:0048546 231 0.079
cellular component biogenesis GO:0044085 178 0.076
response to unfolded protein GO:0006986 2 0.073
Worm
regulation of nuclease activity GO:0032069 1 0.072
biosynthetic process GO:0009058 294 0.069
modification dependent protein catabolic process GO:0019941 3 0.069
multicellular organism growth GO:0035264 4 0.068
regulation of binding GO:0051098 3 0.062
cell migration GO:0016477 237 0.062
central nervous system development GO:0007417 387 0.061
mitotic cell cycle GO:0000278 64 0.059
inner ear development GO:0048839 126 0.058
cell death GO:0008219 121 0.054
cell substrate junction assembly GO:0007044 2 0.054
hydrogen peroxide metabolic process GO:0042743 2 0.052
extrinsic apoptotic signaling pathway GO:0097191 3 0.049
cellular protein catabolic process GO:0044257 4 0.049
digestive tract development GO:0048565 265 0.048
regulation of multicellular organism growth GO:0040014 4 0.047
positive regulation of transport GO:0051050 2 0.046
regulation of metabolic process GO:0019222 359 0.045
cell projection morphogenesis GO:0048858 244 0.045
negative regulation of biological process GO:0048519 304 0.045
otolith development GO:0048840 32 0.045
embryonic organ development GO:0048568 381 0.044
protein metabolic process GO:0019538 183 0.044
immune system development GO:0002520 191 0.044
lipid storage GO:0019915 1 0.043
female meiotic division GO:0007143 2 0.042
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.042
maintenance of location GO:0051235 4 0.042
cell cycle GO:0007049 93 0.041
morphogenesis of an epithelium GO:0002009 333 0.041
modification dependent macromolecule catabolic process GO:0043632 3 0.041
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.041
cellular component movement GO:0006928 335 0.040
immune system process GO:0002376 241 0.040
embryo development ending in birth or egg hatching GO:0009792 271 0.039
hemopoiesis GO:0030097 183 0.038
apoptotic process GO:0006915 116 0.038
negative regulation of cell death GO:0060548 60 0.037
system process GO:0003008 185 0.037
endodermal digestive tract morphogenesis GO:0061031 2 0.037
generation of neurons GO:0048699 385 0.037
regulation of cell death GO:0010941 103 0.037
single organism localization GO:1902578 225 0.036
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.034
regulation of signaling GO:0023051 235 0.033
response to antibiotic GO:0046677 1 0.033
regulation of cellular response to growth factor stimulus GO:0090287 35 0.033
single organism organelle organization GO:1902589 199 0.032
golgi vesicle transport GO:0048193 3 0.032
protein targeting to nucleus GO:0044744 3 0.032
cell part morphogenesis GO:0032990 246 0.032
protein modification process GO:0036211 100 0.031
proteasomal protein catabolic process GO:0010498 2 0.031
negative regulation of cellular process GO:0048523 283 0.031
macromolecule modification GO:0043412 111 0.031
establishment of localization in cell GO:0051649 77 0.031
heart development GO:0007507 313 0.031
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.030
cellular protein modification process GO:0006464 100 0.029
neuron projection development GO:0031175 180 0.029
multi organism process GO:0051704 134 0.029
cell projection organization GO:0030030 284 0.028
gastrulation GO:0007369 208 0.028
regulation of localization GO:0032879 104 0.028
regulation of cell communication GO:0010646 232 0.028
response to abiotic stimulus GO:0009628 122 0.027
brain development GO:0007420 293 0.027
positive regulation of catabolic process GO:0009896 4 0.027
death GO:0016265 121 0.027
sexual reproduction GO:0019953 36 0.027
neurological system process GO:0050877 62 0.026
glycosylation GO:0070085 11 0.026
determination of left right symmetry GO:0007368 179 0.026
programmed cell death GO:0012501 119 0.025
carboxylic acid metabolic process GO:0019752 22 0.025
macromolecule biosynthetic process GO:0009059 227 0.025
cellular macromolecule metabolic process GO:0044260 391 0.025
regulation of developmental process GO:0050793 247 0.024
organonitrogen compound metabolic process GO:1901564 74 0.024
cellular biosynthetic process GO:0044249 286 0.024
cell junction organization GO:0034330 11 0.024
cell morphogenesis involved in differentiation GO:0000904 195 0.023
neuron development GO:0048666 262 0.023
reactive oxygen species biosynthetic process GO:1903409 1 0.023
ubiquitin dependent protein catabolic process GO:0006511 3 0.023
phagocytosis GO:0006909 3 0.023
cellular response to organic cyclic compound GO:0071407 38 0.023
rna biosynthetic process GO:0032774 181 0.022
single organism intracellular transport GO:1902582 25 0.022
protein glycosylation GO:0006486 9 0.022
embryonic organ morphogenesis GO:0048562 274 0.022
positive regulation of developmental process GO:0051094 50 0.022
negative regulation of macromolecule metabolic process GO:0010605 76 0.022
embryonic heart tube morphogenesis GO:0003143 108 0.022
gamete generation GO:0007276 33 0.022
regulation of transcription dna templated GO:0006355 213 0.022
regulation of signal transduction GO:0009966 225 0.022
positive regulation of embryonic development GO:0040019 3 0.021
regulation of protein ubiquitination GO:0031396 3 0.021
embryonic heart tube development GO:0035050 133 0.021
negative regulation of cell communication GO:0010648 96 0.021
positive regulation of cellular catabolic process GO:0031331 3 0.021
regulation of biosynthetic process GO:0009889 250 0.020
head development GO:0060322 303 0.020
neuron differentiation GO:0030182 353 0.020
epidermal cell differentiation GO:0009913 36 0.020
regulation of apoptotic process GO:0042981 98 0.020
behavior GO:0007610 74 0.020
sensory perception of mechanical stimulus GO:0050954 16 0.020
cell aging GO:0007569 2 0.020
negative regulation of apoptotic process GO:0043066 55 0.019
cellular response to endogenous stimulus GO:0071495 68 0.019
spermatid development GO:0007286 2 0.019
response to external stimulus GO:0009605 264 0.019
regulation of nucleic acid templated transcription GO:1903506 213 0.018
embryonic cranial skeleton morphogenesis GO:0048701 90 0.018
regulation of multicellular organismal process GO:0051239 277 0.018
regulation of blood coagulation GO:0030193 1 0.018
cell fate commitment GO:0045165 99 0.018
regulation of anatomical structure morphogenesis GO:0022603 130 0.018
cellular aromatic compound metabolic process GO:0006725 295 0.018
cellular response to starvation GO:0009267 1 0.017
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.017
positive regulation of cellular carbohydrate metabolic process GO:0010676 1 0.017
protein import GO:0017038 3 0.017
response to heat GO:0009408 6 0.017
cellular response to reactive oxygen species GO:0034614 2 0.017
regulation of cellular amino acid metabolic process GO:0006521 0 0.017
axon development GO:0061564 166 0.017
nucleocytoplasmic transport GO:0006913 4 0.017
mononuclear cell proliferation GO:0032943 1 0.016
organic cyclic compound metabolic process GO:1901360 301 0.016
cellular nitrogen compound metabolic process GO:0034641 290 0.016
regulation of blood vessel size GO:0050880 2 0.016
cytokinesis GO:0000910 3 0.016
cytoskeleton dependent cytokinesis GO:0061640 3 0.016
oocyte maturation GO:0001556 4 0.016
metal ion homeostasis GO:0055065 26 0.016
organic substance catabolic process GO:1901575 28 0.016
regulation of intracellular protein transport GO:0033157 3 0.016
hematopoietic or lymphoid organ development GO:0048534 191 0.016
lymphocyte proliferation GO:0046651 1 0.016
microtubule based process GO:0007017 60 0.015
regulation of cell activation GO:0050865 1 0.015
axonogenesis GO:0007409 152 0.015
organelle localization GO:0051640 49 0.015
stem cell maintenance GO:0019827 4 0.015
meiotic cell cycle process GO:1903046 3 0.015
oxoacid metabolic process GO:0043436 31 0.015
regulation of epithelial cell proliferation GO:0050678 3 0.015
localization of cell GO:0051674 244 0.015
startle response GO:0001964 4 0.015
neuron projection morphogenesis GO:0048812 161 0.015
regulation of cellular biosynthetic process GO:0031326 245 0.015
skeletal system morphogenesis GO:0048705 102 0.015
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.015
nucleobase containing compound biosynthetic process GO:0034654 205 0.015
establishment of protein localization to organelle GO:0072594 4 0.015
regulation of cellular amine metabolic process GO:0033238 0 0.015
notch signaling pathway GO:0007219 35 0.015
localization within membrane GO:0051668 1 0.014
regulation of wound healing GO:0061041 2 0.014
nitrogen compound metabolic process GO:0006807 319 0.014
transport GO:0006810 220 0.014
epithelial cell differentiation GO:0030855 116 0.014
growth GO:0040007 174 0.014
cell migration involved in gastrulation GO:0042074 79 0.014
aromatic compound biosynthetic process GO:0019438 217 0.013
neuroblast proliferation GO:0007405 2 0.013
reproduction GO:0000003 40 0.013
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.013
response to cold GO:0009409 4 0.013
response to estrogen GO:0043627 27 0.013
rna metabolic process GO:0016070 219 0.013
transcription from rna polymerase ii promoter GO:0006366 80 0.013
regulation of reproductive process GO:2000241 4 0.013
cellular macromolecule biosynthetic process GO:0034645 224 0.013
regulation of cytoplasmic transport GO:1903649 4 0.013
dopaminergic neuron differentiation GO:0071542 14 0.013
protein import into nucleus GO:0006606 3 0.013
anatomical structure arrangement GO:0048532 2 0.013
nuclear import GO:0051170 3 0.013
transcription dna templated GO:0006351 181 0.013
mesenchyme development GO:0060485 127 0.013
autophagy GO:0006914 4 0.012
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.012
regulation of nucleotide catabolic process GO:0030811 2 0.012
establishment of localization GO:0051234 244 0.012
regulation of programmed cell death GO:0043067 101 0.012
amine metabolic process GO:0009308 2 0.012
glycoprotein metabolic process GO:0009100 23 0.012
regulation of dna replication GO:0006275 3 0.012
negative regulation of programmed cell death GO:0043069 58 0.012
regulation of cellular metabolic process GO:0031323 320 0.012
striated muscle cell differentiation GO:0051146 129 0.012
regulation of gene expression GO:0010468 265 0.012
cell maturation GO:0048469 23 0.012
collagen biosynthetic process GO:0032964 2 0.012
spindle assembly GO:0051225 2 0.012
regulation of tube size GO:0035150 2 0.012
cellular localization GO:0051641 97 0.012
glial cell migration GO:0008347 3 0.012
heterocycle metabolic process GO:0046483 290 0.012
cellular response to extracellular stimulus GO:0031668 2 0.012
macromolecule catabolic process GO:0009057 15 0.011
chemotaxis GO:0006935 104 0.011
negative regulation of protein phosphorylation GO:0001933 4 0.011
double strand break repair GO:0006302 3 0.011
positive regulation of cellular process GO:0048522 201 0.011
neural nucleus development GO:0048857 15 0.011
positive regulation of nuclease activity GO:0032075 1 0.011
regulation of molecular function GO:0065009 70 0.011
heart looping GO:0001947 94 0.011
hemidesmosome assembly GO:0031581 1 0.011
spindle assembly involved in mitosis GO:0090307 1 0.011
regulation of macromolecule metabolic process GO:0060255 317 0.011
ear development GO:0043583 127 0.011
positive regulation of notch signaling pathway GO:0045747 3 0.011
lymphocyte activation GO:0046649 10 0.011
regulation of glucose transport GO:0010827 1 0.011
myeloid cell homeostasis GO:0002262 56 0.011
male gamete generation GO:0048232 7 0.010
response to hypoxia GO:0001666 25 0.010
regulation of protein transport GO:0051223 3 0.010
positive regulation of response to stimulus GO:0048584 80 0.010
cellular response to nutrient levels GO:0031669 2 0.010
muscle organ development GO:0007517 101 0.010

pdip5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.049
auditory system disease DOID:2742 0 0.044
autosomal dominant nonsyndromic deafness DOID:0050564 0 0.044
nonsyndromic deafness DOID:0050563 0 0.044
sensory system disease DOID:0050155 0 0.044
nervous system disease DOID:863 0 0.044
cancer DOID:162 0 0.010
disease of cellular proliferation DOID:14566 0 0.010