Danio rerio

0 known processes

fbxl4

F-box and leucine-rich repeat protein 4

(Aliases: zgc:92297)

fbxl4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
synaptic growth at neuromuscular junction GO:0051124 2 0.091
regulation of synapse assembly GO:0051963 3 0.068
regulation of metabolic process GO:0019222 359 0.064
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.061
larval development GO:0002164 2 0.059
regulation of synapse organization GO:0050807 3 0.057
protein localization to nucleus GO:0034504 3 0.055
positive regulation of catabolic process GO:0009896 4 0.052
nucleobase containing compound metabolic process GO:0006139 274 0.050
vasculature development GO:0001944 278 0.050
locomotion GO:0040011 313 0.049
positive regulation of cellular catabolic process GO:0031331 3 0.048
regulation of reproductive process GO:2000241 4 0.045
positive regulation of transport GO:0051050 2 0.043
regulation of signal transduction GO:0009966 225 0.042
negative regulation of protein phosphorylation GO:0001933 4 0.038
signal transduction GO:0007165 455 0.035
cell migration GO:0016477 237 0.035
aging GO:0007568 2 0.033
organelle organization GO:0006996 227 0.033
localization of cell GO:0051674 244 0.033
response to uv GO:0009411 3 0.032
growth GO:0040007 174 0.032
biosynthetic process GO:0009058 294 0.032
nucleic acid templated transcription GO:0097659 181 0.032
cellular biosynthetic process GO:0044249 286 0.031
meiotic nuclear division GO:0007126 4 0.031
cellular component morphogenesis GO:0032989 336 0.031
response to xenobiotic stimulus GO:0009410 45 0.031
embryonic organ development GO:0048568 381 0.030
establishment of synaptic vesicle localization GO:0097480 1 0.030
single organism nuclear import GO:1902593 3 0.029
cellular component assembly GO:0022607 170 0.029
protein import into nucleus GO:0006606 3 0.029
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.029
regulation of multicellular organismal process GO:0051239 277 0.029
response to chemical GO:0042221 320 0.028
nitrogen compound metabolic process GO:0006807 319 0.027
rna metabolic process GO:0016070 219 0.027
ameboidal type cell migration GO:0001667 143 0.027
synaptic vesicle transport GO:0048489 1 0.027
blood vessel morphogenesis GO:0048514 216 0.027
regulation of tube size GO:0035150 2 0.026
regulation of macromolecule biosynthetic process GO:0010556 225 0.026
positive regulation of cellular process GO:0048522 201 0.026
cellular nitrogen compound metabolic process GO:0034641 290 0.025
peptidyl lysine acetylation GO:0018394 2 0.025
cellular response to xenobiotic stimulus GO:0071466 35 0.025
positive regulation of biological process GO:0048518 253 0.025
somatic muscle development GO:0007525 4 0.025
macromolecule biosynthetic process GO:0009059 227 0.024
extrinsic apoptotic signaling pathway GO:0097191 3 0.024
regulation of protein transport GO:0051223 3 0.023
adult behavior GO:0030534 2 0.023
positive regulation of cell cycle GO:0045787 3 0.023
apoptotic process involved in development GO:1902742 2 0.023
neuron neuron synaptic transmission GO:0007270 1 0.022
eye development GO:0001654 277 0.022
negative regulation of kinase activity GO:0033673 4 0.022
regulation of multicellular organism growth GO:0040014 4 0.022
maintenance of location GO:0051235 4 0.022
multicellular organism growth GO:0035264 4 0.022
regulation of protein catabolic process GO:0042176 1 0.022
neurotransmitter transport GO:0006836 2 0.022
cell surface receptor signaling pathway GO:0007166 325 0.021
regulation of cellular metabolic process GO:0031323 320 0.021
proteasomal protein catabolic process GO:0010498 2 0.021
determination of bilateral symmetry GO:0009855 204 0.021
negative regulation of metabolic process GO:0009892 86 0.021
hormone secretion GO:0046879 2 0.021
establishment of protein localization to organelle GO:0072594 4 0.021
positive regulation of cytoskeleton organization GO:0051495 3 0.021
peptide metabolic process GO:0006518 1 0.021
negative regulation of protein kinase activity GO:0006469 4 0.021
synaptic vesicle localization GO:0097479 1 0.021
regulation of cell communication GO:0010646 232 0.021
centrosome cycle GO:0007098 1 0.020
nuclear import GO:0051170 3 0.020
mitochondrion organization GO:0007005 4 0.020
transport GO:0006810 220 0.020
mesenchyme development GO:0060485 127 0.020
developmental programmed cell death GO:0010623 4 0.020
transcription dna templated GO:0006351 181 0.020
amine metabolic process GO:0009308 2 0.020
organic substance biosynthetic process GO:1901576 289 0.020
hormone transport GO:0009914 2 0.020
protein import GO:0017038 3 0.020
erk1 and erk2 cascade GO:0070371 4 0.020
positive regulation of cellular component biogenesis GO:0044089 3 0.020
cellular response to extracellular stimulus GO:0031668 2 0.020
regulation of erk1 and erk2 cascade GO:0070372 4 0.020
regulation of synaptic plasticity GO:0048167 1 0.020
dicarboxylic acid transport GO:0006835 1 0.019
cellular response to starvation GO:0009267 1 0.019
internal protein amino acid acetylation GO:0006475 2 0.019
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.019
protein acylation GO:0043543 3 0.019
single organism metabolic process GO:0044710 217 0.019
regulation of binding GO:0051098 3 0.019
regulation of cellular amino acid metabolic process GO:0006521 0 0.018
tissue remodeling GO:0048771 4 0.018
regulation of signaling GO:0023051 235 0.018
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.018
regulation of nucleotide catabolic process GO:0030811 2 0.018
cellular response to nutrient levels GO:0031669 2 0.018
multi organism process GO:0051704 134 0.018
lateral inhibition GO:0046331 1 0.018
regulation of transcription dna templated GO:0006355 213 0.018
regulation of cellular ketone metabolic process GO:0010565 7 0.018
cellular response to oxygen levels GO:0071453 1 0.018
cellular macromolecule metabolic process GO:0044260 391 0.018
cell substrate adhesion GO:0031589 4 0.018
regulation of cellular amine metabolic process GO:0033238 0 0.017
nucleocytoplasmic transport GO:0006913 4 0.017
meiotic cell cycle process GO:1903046 3 0.017
aromatic compound biosynthetic process GO:0019438 217 0.017
regulation of purine nucleotide catabolic process GO:0033121 2 0.017
xenobiotic metabolic process GO:0006805 4 0.017
fatty acid catabolic process GO:0009062 1 0.017
guanosine containing compound catabolic process GO:1901069 2 0.017
guanosine containing compound metabolic process GO:1901068 4 0.017
gtp catabolic process GO:0006184 2 0.017
lipid storage GO:0019915 1 0.017
cellular macromolecule biosynthetic process GO:0034645 224 0.017
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.016
regulation of nitrogen compound metabolic process GO:0051171 251 0.016
protein dephosphorylation GO:0006470 3 0.016
cellular amine metabolic process GO:0044106 2 0.016
organic cyclic compound biosynthetic process GO:1901362 223 0.016
nucleic acid metabolic process GO:0090304 244 0.016
cellular aromatic compound metabolic process GO:0006725 295 0.016
gtp metabolic process GO:0046039 4 0.016
nuclear transport GO:0051169 4 0.016
cellular respiration GO:0045333 3 0.016
lipid oxidation GO:0034440 1 0.016
peptidyl serine modification GO:0018209 2 0.016
phosphatidylinositol mediated signaling GO:0048015 2 0.016
negative regulation of biological process GO:0048519 304 0.016
regulation of primary metabolic process GO:0080090 311 0.016
cellular protein catabolic process GO:0044257 4 0.016
organic cyclic compound metabolic process GO:1901360 301 0.016
protein polyubiquitination GO:0000209 4 0.016
blood vessel development GO:0001568 246 0.016
positive regulation of gtp catabolic process GO:0033126 1 0.016
heart development GO:0007507 313 0.015
heterocycle biosynthetic process GO:0018130 215 0.015
head development GO:0060322 303 0.015
angiogenesis GO:0001525 158 0.015
cellular response to external stimulus GO:0071496 2 0.015
protein targeting to nucleus GO:0044744 3 0.015
tube morphogenesis GO:0035239 349 0.015
neuron differentiation GO:0030182 353 0.015
peptide transport GO:0015833 1 0.015
regulation of establishment of protein localization GO:0070201 4 0.015
vacuolar transport GO:0007034 2 0.015
stem cell proliferation GO:0072089 4 0.015
response to stress GO:0006950 263 0.015
modification dependent protein catabolic process GO:0019941 3 0.015
specification of symmetry GO:0009799 204 0.015
regulation of oocyte development GO:0060281 3 0.015
cellular response to light stimulus GO:0071482 4 0.015
phagocytosis GO:0006909 3 0.015
protein acetylation GO:0006473 2 0.015
negative regulation of mapk cascade GO:0043409 4 0.015
lipid catabolic process GO:0016042 4 0.015
cellular response to chemical stimulus GO:0070887 157 0.015
autophagy GO:0006914 4 0.015
cell cycle arrest GO:0007050 1 0.015
regulation of rna metabolic process GO:0051252 224 0.015
secondary metabolic process GO:0019748 3 0.015
negative regulation of macromolecule metabolic process GO:0010605 76 0.015
sensory organ morphogenesis GO:0090596 200 0.015
neurotransmitter secretion GO:0007269 2 0.015
atp catabolic process GO:0006200 4 0.014
pancreas development GO:0031016 84 0.014
positive regulation of secretion GO:0051047 1 0.014
regulation of jak stat cascade GO:0046425 3 0.014
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.014
sensory perception of chemical stimulus GO:0007606 3 0.014
positive regulation of stem cell proliferation GO:2000648 1 0.014
regulation of developmental process GO:0050793 247 0.014
membrane invagination GO:0010324 1 0.014
single organism membrane fusion GO:0044801 2 0.014
skeletal system development GO:0001501 181 0.014
positive regulation of gtpase activity GO:0043547 1 0.014
regulation of intracellular protein transport GO:0033157 3 0.014
regulation of circadian rhythm GO:0042752 4 0.014
embryonic organ morphogenesis GO:0048562 274 0.014
nucleobase containing compound biosynthetic process GO:0034654 205 0.014
skeletal system morphogenesis GO:0048705 102 0.014
positive regulation of nucleotide catabolic process GO:0030813 1 0.014
response to organic substance GO:0010033 153 0.014
positive regulation of protein complex assembly GO:0031334 2 0.014
small gtpase mediated signal transduction GO:0007264 8 0.014
regulation of transporter activity GO:0032409 2 0.014
cell motility GO:0048870 244 0.014
regulation of ras gtpase activity GO:0032318 2 0.014
regulation of cytoplasmic transport GO:1903649 4 0.014
regulation of mrna processing GO:0050684 3 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.013
protein homooligomerization GO:0051260 3 0.013
cellular modified amino acid metabolic process GO:0006575 3 0.013
internal peptidyl lysine acetylation GO:0018393 2 0.013
macroautophagy GO:0016236 1 0.013
synaptic vesicle endocytosis GO:0048488 1 0.013
inositol lipid mediated signaling GO:0048017 2 0.013
positive regulation of immune effector process GO:0002699 3 0.013
heterocycle metabolic process GO:0046483 290 0.013
response to unfolded protein GO:0006986 2 0.013
regulation of dendrite development GO:0050773 3 0.013
regulation of organ growth GO:0046620 3 0.013
cellular ketone metabolic process GO:0042180 11 0.013
negative regulation of response to cytokine stimulus GO:0060761 2 0.013
rna modification GO:0009451 2 0.013
cellular response to hypoxia GO:0071456 1 0.013
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.013
heart looping GO:0001947 94 0.013
eye morphogenesis GO:0048592 144 0.013
oxoacid metabolic process GO:0043436 31 0.013
regulation of biosynthetic process GO:0009889 250 0.013
single organism localization GO:1902578 225 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.013
post embryonic organ development GO:0048569 4 0.013
cellular component biogenesis GO:0044085 178 0.013
camera type eye development GO:0043010 222 0.013
death GO:0016265 121 0.013
gene expression GO:0010467 252 0.013
regulation of response to cytokine stimulus GO:0060759 3 0.013
regulation of cellular biosynthetic process GO:0031326 245 0.013
post embryonic morphogenesis GO:0009886 4 0.013
regulation of fatty acid metabolic process GO:0019217 1 0.013
regulation of cell activation GO:0050865 1 0.013
golgi vesicle transport GO:0048193 3 0.013
developmental growth GO:0048589 166 0.013
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.013
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.013
production of molecular mediator of immune response GO:0002440 2 0.013
embryonic cranial skeleton morphogenesis GO:0048701 90 0.013
protein k48 linked ubiquitination GO:0070936 1 0.013
negative regulation of signal transduction GO:0009968 94 0.013
cellular amino acid metabolic process GO:0006520 7 0.012
meiosis i GO:0007127 1 0.012
transcription from rna polymerase ii promoter GO:0006366 80 0.012
ribonucleoside monophosphate catabolic process GO:0009158 4 0.012
digestive system development GO:0055123 289 0.012
female gonad development GO:0008585 4 0.012
regulation of organelle assembly GO:1902115 4 0.012
organonitrogen compound metabolic process GO:1901564 74 0.012
positive regulation of nucleoside metabolic process GO:0045979 1 0.012
establishment of localization GO:0051234 244 0.012
immune system development GO:0002520 191 0.012
spindle assembly involved in mitosis GO:0090307 1 0.012
response to hexose GO:0009746 3 0.012
response to vitamin GO:0033273 3 0.012
odontogenesis of dentin containing tooth GO:0042475 1 0.012
regulation of nucleoside metabolic process GO:0009118 2 0.012
determination of left right symmetry GO:0007368 179 0.012
regulation of response to extracellular stimulus GO:0032104 1 0.012
regulation of gene expression GO:0010468 265 0.012
morphogenesis of an epithelium GO:0002009 333 0.012
sensory organ development GO:0007423 393 0.012
cell projection morphogenesis GO:0048858 244 0.012
cell morphogenesis GO:0000902 289 0.012
er nucleus signaling pathway GO:0006984 2 0.012
positive regulation of cell division GO:0051781 2 0.012
g1 s transition of mitotic cell cycle GO:0000082 1 0.012
regulation of hormone secretion GO:0046883 2 0.012
sequestering of calcium ion GO:0051208 3 0.012
negative regulation of defense response GO:0031348 2 0.012
synaptic vesicle recycling GO:0036465 1 0.012
embryonic limb morphogenesis GO:0030326 2 0.012
cellular response to decreased oxygen levels GO:0036294 1 0.012
regulation of blood vessel size GO:0050880 2 0.012
brain development GO:0007420 293 0.012
cellular lipid catabolic process GO:0044242 3 0.012
positive regulation of map kinase activity GO:0043406 3 0.012
regulation of nucleic acid templated transcription GO:1903506 213 0.012
somatic stem cell maintenance GO:0035019 1 0.011
cell death GO:0008219 121 0.011
negative regulation of cellular process GO:0048523 283 0.011
regulation of gtpase activity GO:0043087 2 0.011
response to alkaloid GO:0043279 2 0.011
regulation of gtp catabolic process GO:0033124 2 0.011
female sex differentiation GO:0046660 4 0.011
positive regulation of cellular metabolic process GO:0031325 94 0.011
cognition GO:0050890 1 0.011
ras protein signal transduction GO:0007265 7 0.011
lipid metabolic process GO:0006629 52 0.011
cell aging GO:0007569 2 0.011
negative regulation of reproductive process GO:2000242 3 0.011
alcohol biosynthetic process GO:0046165 2 0.011
neuron projection morphogenesis GO:0048812 161 0.011
cellular response to topologically incorrect protein GO:0035967 2 0.011
small molecule metabolic process GO:0044281 77 0.011
stem cell maintenance GO:0019827 4 0.011
programmed cell death GO:0012501 119 0.011
positive regulation of translation GO:0045727 1 0.011
pole plasm assembly GO:0007315 4 0.011
regulation of protein targeting GO:1903533 2 0.011
cellular component movement GO:0006928 335 0.011
rna biosynthetic process GO:0032774 181 0.011
cellular response to radiation GO:0071478 4 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.011
response to drug GO:0042493 3 0.011
negative regulation of autophagy GO:0010507 1 0.011
macromolecular complex subunit organization GO:0043933 74 0.011
organic acid metabolic process GO:0006082 31 0.011
positive regulation of ras gtpase activity GO:0032320 1 0.011
positive regulation of dna metabolic process GO:0051054 1 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.011
nucleoside monophosphate catabolic process GO:0009125 4 0.011
modification dependent macromolecule catabolic process GO:0043632 3 0.011
carboxylic acid metabolic process GO:0019752 22 0.011
regulation of myotube differentiation GO:0010830 2 0.011
regulation of rho protein signal transduction GO:0035023 2 0.011
positive regulation of apoptotic signaling pathway GO:2001235 1 0.011
regulation of biological quality GO:0065008 263 0.011
response to monosaccharide GO:0034284 3 0.011
negative regulation of map kinase activity GO:0043407 2 0.011
cell cycle g1 s phase transition GO:0044843 1 0.011
epithelial tube morphogenesis GO:0060562 148 0.011
regulation of multicellular organismal development GO:2000026 223 0.010
generation of neurons GO:0048699 385 0.010
carboxylic acid catabolic process GO:0046395 3 0.010
immune system process GO:0002376 241 0.010
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.010
regulation of carbohydrate metabolic process GO:0006109 4 0.010
activation of mapk activity GO:0000187 3 0.010
cellular response to unfolded protein GO:0034620 2 0.010
sprouting angiogenesis GO:0002040 53 0.010
regulation of protein import into nucleus GO:0042306 2 0.010
compound eye development GO:0048749 2 0.010
intracellular signal transduction GO:0035556 85 0.010
glial cell migration GO:0008347 3 0.010
cellular amide metabolic process GO:0043603 4 0.010
sensory perception of smell GO:0007608 2 0.010
positive regulation of blood circulation GO:1903524 2 0.010
regulation of meiotic cell cycle GO:0051445 1 0.010
rna localization GO:0006403 4 0.010
embryonic hemopoiesis GO:0035162 53 0.010
response to hydrogen peroxide GO:0042542 3 0.010
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.010
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.010
forebrain cell migration GO:0021885 1 0.010

fbxl4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.027
disease of metabolism DOID:0014667 0 0.027
disease of cellular proliferation DOID:14566 0 0.018
cancer DOID:162 0 0.018
organ system cancer DOID:0050686 0 0.014
musculoskeletal system disease DOID:17 0 0.013
immune system disease DOID:2914 0 0.010