Danio rerio

15 known processes

gbx2

gastrulation brain homeo box 2

(Aliases: gbx-2,wu:fd07f12,fd07f12)

gbx2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
central nervous system development GO:0007417 387 0.994
sensory organ development GO:0007423 393 0.987
Mouse
sensory organ morphogenesis GO:0090596 200 0.985
Mouse
regionalization GO:0003002 274 0.978
Zebrafish Mouse
neuron differentiation GO:0030182 353 0.972
Zebrafish Mouse
brain development GO:0007420 293 0.972
head development GO:0060322 303 0.961
ear development GO:0043583 127 0.960
Mouse
digestive tract development GO:0048565 265 0.959
camera type eye morphogenesis GO:0048593 108 0.953
appendage morphogenesis GO:0035107 56 0.948
eye development GO:0001654 277 0.943
generation of neurons GO:0048699 385 0.940
Zebrafish Mouse
mesoderm morphogenesis GO:0048332 51 0.936
retina development in camera type eye GO:0060041 146 0.915
ear morphogenesis GO:0042471 64 0.912
Mouse
appendage development GO:0048736 80 0.910
nucleic acid metabolic process GO:0090304 244 0.906
Fly
camera type eye development GO:0043010 222 0.903
mesoderm development GO:0007498 88 0.903
cell fate commitment GO:0045165 99 0.895
Zebrafish
digestive system development GO:0055123 289 0.891
embryonic camera type eye development GO:0031076 29 0.884
tube morphogenesis GO:0035239 349 0.873
Mouse
retina morphogenesis in camera type eye GO:0060042 79 0.868
embryonic appendage morphogenesis GO:0035113 30 0.865
regulation of cellular metabolic process GO:0031323 320 0.858
Fly
embryonic organ development GO:0048568 381 0.857
Mouse
embryonic skeletal system morphogenesis GO:0048704 93 0.855
regulation of nitrogen compound metabolic process GO:0051171 251 0.851
Fly
macromolecule biosynthetic process GO:0009059 227 0.844
Fly
eye morphogenesis GO:0048592 144 0.839
embryonic retina morphogenesis in camera type eye GO:0060059 22 0.836
sensory system development GO:0048880 76 0.826
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.816
Fly
dorsal ventral pattern formation GO:0009953 125 0.816
transcription dna templated GO:0006351 181 0.814
Fly
cellular macromolecule biosynthetic process GO:0034645 224 0.812
Fly
rostrocaudal neural tube patterning GO:0021903 29 0.812
Zebrafish Mouse
regulation of rna biosynthetic process GO:2001141 213 0.810
Fly
rna biosynthetic process GO:0032774 181 0.809
Fly
cellular aromatic compound metabolic process GO:0006725 295 0.806
Fly
inner ear morphogenesis GO:0042472 63 0.801
Mouse
gene expression GO:0010467 252 0.799
Fly
pectoral fin development GO:0033339 50 0.798
mesoderm formation GO:0001707 43 0.790
nucleobase containing compound biosynthetic process GO:0034654 205 0.787
Fly
regulation of endodermal cell fate specification GO:0042663 15 0.784
regulation of primary metabolic process GO:0080090 311 0.781
Fly
positive regulation of cellular process GO:0048522 201 0.779
inner ear development GO:0048839 126 0.777
Mouse
chordate embryonic development GO:0043009 271 0.775
Zebrafish Mouse
organic cyclic compound biosynthetic process GO:1901362 223 0.761
Fly
formation of primary germ layer GO:0001704 62 0.760
signal transduction GO:0007165 455 0.749
Zebrafish
specification of symmetry GO:0009799 204 0.735
cellular biosynthetic process GO:0044249 286 0.730
Fly
organic cyclic compound metabolic process GO:1901360 301 0.730
Fly
nucleobase containing compound metabolic process GO:0006139 274 0.730
Fly
regulation of macromolecule metabolic process GO:0060255 317 0.729
Fly
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.728
rna metabolic process GO:0016070 219 0.723
Fly
neuron projection guidance GO:0097485 86 0.722
Mouse
eye photoreceptor cell differentiation GO:0001754 45 0.719
midbrain development GO:0030901 28 0.718
bmp signaling pathway GO:0030509 52 0.717
nephron morphogenesis GO:0072028 2 0.712
regulation of gene expression GO:0010468 265 0.710
Fly
hindbrain morphogenesis GO:0021575 22 0.708
regulation of metabolic process GO:0019222 359 0.696
Fly
larval development GO:0002164 2 0.692
embryonic pectoral fin morphogenesis GO:0035118 24 0.690
hindbrain development GO:0030902 91 0.685
regulation of rna metabolic process GO:0051252 224 0.681
Fly
determination of dorsal ventral asymmetry GO:0048262 34 0.677
neural tube patterning GO:0021532 33 0.675
Zebrafish Mouse
determination of bilateral symmetry GO:0009855 204 0.665
chemotaxis GO:0006935 104 0.664
Mouse
digestive tract morphogenesis GO:0048546 231 0.656
heterocycle metabolic process GO:0046483 290 0.653
Fly
photoreceptor cell differentiation GO:0046530 55 0.648
forebrain neuron development GO:0021884 7 0.644
Mouse
response to external stimulus GO:0009605 264 0.644
Mouse
embryo development ending in birth or egg hatching GO:0009792 271 0.638
Zebrafish Mouse
regulation of anterior head development GO:2000742 2 0.635
photoreceptor cell fate specification GO:0043704 1 0.634
ectodermal placode development GO:0071696 37 0.622
aromatic compound biosynthetic process GO:0019438 217 0.622
Fly
regulation of macromolecule biosynthetic process GO:0010556 225 0.620
Fly
forebrain regionalization GO:0021871 4 0.619
photoreceptor cell fate commitment GO:0046552 1 0.619
negative regulation of cellular process GO:0048523 283 0.615
muscle organ development GO:0007517 101 0.602
embryonic limb morphogenesis GO:0030326 2 0.601
nitrogen compound metabolic process GO:0006807 319 0.599
Fly
otic placode formation GO:0043049 23 0.596
gastrulation GO:0007369 208 0.594
lateral line system development GO:0048925 76 0.589
midbrain hindbrain boundary development GO:0030917 23 0.585
Zebrafish Mouse
endocrine system development GO:0035270 65 0.581
Zebrafish
nephron epithelium morphogenesis GO:0072088 1 0.579
enzyme linked receptor protein signaling pathway GO:0007167 106 0.578
retina layer formation GO:0010842 24 0.576
pancreas development GO:0031016 84 0.573
Zebrafish
neural retina development GO:0003407 49 0.573
nucleic acid templated transcription GO:0097659 181 0.571
Fly
axonogenesis GO:0007409 152 0.569
Mouse
pronephric glomerulus morphogenesis GO:0035775 6 0.569
neuroblast fate determination GO:0007400 1 0.564
mesenchyme development GO:0060485 127 0.562
Mouse
regulation of nucleic acid templated transcription GO:1903506 213 0.562
Fly
lateral line development GO:0048882 66 0.561
locomotion GO:0040011 313 0.560
Mouse
transcription from rna polymerase ii promoter GO:0006366 80 0.560
hindbrain formation GO:0021576 3 0.551
cell fate specification GO:0001708 68 0.550
Zebrafish
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.547
cellular nitrogen compound biosynthetic process GO:0044271 218 0.545
Fly
heart development GO:0007507 313 0.541
nephron tubule morphogenesis GO:0072078 1 0.530
epithelial cell differentiation GO:0030855 116 0.529
Zebrafish
anterior posterior pattern specification GO:0009952 152 0.528
Zebrafish Mouse
neural tube development GO:0021915 62 0.522
Zebrafish Mouse
camera type eye photoreceptor cell differentiation GO:0060219 19 0.517
fin morphogenesis GO:0033334 53 0.515
neuromast mantle cell differentiation GO:0048888 1 0.510
heterocycle biosynthetic process GO:0018130 215 0.510
Fly
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.508
cell morphogenesis GO:0000902 289 0.506
Mouse
morphogenesis of embryonic epithelium GO:0016331 30 0.502
forebrain development GO:0030900 96 0.491
Mouse
diencephalon development GO:0021536 58 0.483
Mouse
kidney development GO:0001822 92 0.480
regulation of biosynthetic process GO:0009889 250 0.476
Fly
embryonic camera type eye formation GO:0060900 10 0.474
cellular macromolecule metabolic process GO:0044260 391 0.474
Fly
cell part morphogenesis GO:0032990 246 0.471
Mouse
ectodermal placode formation GO:0060788 26 0.455
negative regulation of biological process GO:0048519 304 0.454
pectoral fin morphogenesis GO:0035138 29 0.442
developmental induction GO:0031128 10 0.439
embryonic skeletal system development GO:0048706 97 0.436
negative regulation of gene expression GO:0010629 65 0.427
skeletal muscle organ development GO:0060538 78 0.425
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.424
otic vesicle morphogenesis GO:0071600 34 0.422
metencephalon development GO:0022037 27 0.419
Mouse
determination of heart left right asymmetry GO:0061371 117 0.415
auditory receptor cell fate determination GO:0042668 2 0.408
organic substance biosynthetic process GO:1901576 289 0.408
Fly
urogenital system development GO:0001655 97 0.406
spinal cord association neuron differentiation GO:0021527 1 0.405
otic vesicle development GO:0071599 42 0.402
mesodermal cell differentiation GO:0048333 21 0.398
positive regulation of gene expression GO:0010628 71 0.383
cell projection morphogenesis GO:0048858 244 0.380
Mouse
cell differentiation in spinal cord GO:0021515 40 0.379
Zebrafish
regulation of retina development in camera type eye GO:1902866 2 0.379
central nervous system neuron differentiation GO:0021953 74 0.378
Zebrafish Mouse
skeletal system development GO:0001501 181 0.377
muscle structure development GO:0061061 196 0.374
cellular nitrogen compound metabolic process GO:0034641 290 0.373
Fly
neuron projection development GO:0031175 180 0.373
Mouse
regulation of inner ear receptor cell differentiation GO:2000980 1 0.372
endodermal cell fate specification GO:0001714 17 0.371
muscle tissue development GO:0060537 110 0.363
cartilage development GO:0051216 96 0.361
posterior lateral line neuromast mantle cell differentiation GO:0048924 1 0.360
heart looping GO:0001947 94 0.360
fourth ventricle development GO:0021592 8 0.358
striated muscle tissue development GO:0014706 110 0.357
central nervous system myelin formation GO:0032289 1 0.356
neuron fate determination GO:0048664 2 0.356
fin development GO:0033333 77 0.352
apoptotic process GO:0006915 116 0.351
brain morphogenesis GO:0048854 18 0.349
morphogenesis of an epithelium GO:0002009 333 0.345
Mouse
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.341
tube formation GO:0035148 25 0.338
positive regulation of metabolic process GO:0009893 108 0.333
biosynthetic process GO:0009058 294 0.331
Fly
renal system development GO:0072001 94 0.330
positive regulation of muscle organ development GO:0048636 1 0.329
rhombomere development GO:0021546 19 0.328
Mouse
regulation of bmp signaling pathway GO:0030510 39 0.328
aorta development GO:0035904 4 0.327
axon guidance GO:0007411 86 0.326
Mouse
otic vesicle formation GO:0030916 27 0.322
epidermis development GO:0008544 48 0.321
posterior lateral line system development GO:0048915 46 0.318
positive regulation of epithelial cell differentiation GO:0030858 2 0.318
neuron fate commitment GO:0048663 26 0.314
Zebrafish
regulation of cell differentiation GO:0045595 142 0.314
response to chemical GO:0042221 320 0.312
Mouse
blood vessel development GO:0001568 246 0.312
Mouse
neural tube formation GO:0001841 16 0.311
hair cell differentiation GO:0035315 32 0.308
regulation of signaling GO:0023051 235 0.307
Zebrafish
stem cell differentiation GO:0048863 117 0.305
Mouse
negative regulation of anterior neural cell fate commitment of the neural plate GO:0022001 1 0.304
regulation of anatomical structure morphogenesis GO:0022603 130 0.302
Zebrafish
inner ear receptor cell development GO:0060119 20 0.299
neuron fate specification GO:0048665 20 0.298
Zebrafish
post anal tail morphogenesis GO:0036342 19 0.297
negative regulation of transcription dna templated GO:0045892 45 0.295
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.290
midbrain hindbrain boundary morphogenesis GO:0021555 5 0.286
Zebrafish Mouse
regulation of multicellular organismal development GO:2000026 223 0.285
Zebrafish Fly
endoderm formation GO:0001706 29 0.284
endodermal cell fate commitment GO:0001711 18 0.282
embryonic epithelial tube formation GO:0001838 17 0.272
homeostatic process GO:0042592 142 0.270
central nervous system myelination GO:0022010 2 0.266
skin development GO:0043588 54 0.265
cerebellum formation GO:0021588 2 0.265
neuromast development GO:0048884 46 0.265
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.264
compound eye development GO:0048749 2 0.263
pharyngeal system development GO:0060037 18 0.262
neuron projection morphogenesis GO:0048812 161 0.260
Mouse
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.259
endodermal cell differentiation GO:0035987 19 0.259
pancreatic a cell development GO:0003322 2 0.258
cellular component morphogenesis GO:0032989 336 0.257
Mouse
positive regulation of cellular biosynthetic process GO:0031328 68 0.256
positive regulation of cellular metabolic process GO:0031325 94 0.256
embryonic cranial skeleton morphogenesis GO:0048701 90 0.256
glial cell differentiation GO:0010001 42 0.256
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.255
regulation of multicellular organismal process GO:0051239 277 0.254
Zebrafish Fly
embryonic camera type eye morphogenesis GO:0048596 19 0.253
positive regulation of rna metabolic process GO:0051254 59 0.252
skeletal system morphogenesis GO:0048705 102 0.249
regulation of cell fate commitment GO:0010453 22 0.247
cell morphogenesis involved in differentiation GO:0000904 195 0.247
Mouse
regulation of transcription dna templated GO:0006355 213 0.246
Fly
regulation of cell communication GO:0010646 232 0.245
Zebrafish
retinal ganglion cell axon guidance GO:0031290 35 0.245
ectodermal placode morphogenesis GO:0071697 32 0.243
regulation of mechanoreceptor differentiation GO:0045631 1 0.242
positive regulation of biological process GO:0048518 253 0.240
neuron projection extension GO:1990138 45 0.239
septum transversum development GO:0003343 4 0.239
regulation of endodermal cell differentiation GO:1903224 15 0.238
sexual reproduction GO:0019953 36 0.237
neural plate pattern specification GO:0060896 12 0.237
Zebrafish
skeletal muscle tissue development GO:0007519 67 0.236
positive regulation of transcription dna templated GO:0045893 57 0.234
posterior lateral line neuromast hair cell differentiation GO:0048923 8 0.233
gland development GO:0048732 143 0.226
cellular response to growth factor stimulus GO:0071363 39 0.225
forebrain neuron differentiation GO:0021879 14 0.220
Mouse
cardiogenic plate morphogenesis GO:0003142 1 0.220
neuroblast differentiation GO:0014016 1 0.216
endoderm development GO:0007492 49 0.216
positive regulation of macromolecule metabolic process GO:0010604 93 0.216
cellular component movement GO:0006928 335 0.214
Mouse
regulation of neurogenesis GO:0050767 87 0.213
regulation of biological quality GO:0065008 263 0.212
epithelial tube morphogenesis GO:0060562 148 0.211
Mouse
hepatic duct development GO:0061011 2 0.211
determination of left right symmetry GO:0007368 179 0.210
auditory receptor cell fate commitment GO:0009912 4 0.208
convergent extension involved in gastrulation GO:0060027 71 0.205
proepicardium development GO:0003342 4 0.205
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.204
mesodermal cell fate specification GO:0007501 12 0.204
thalamus development GO:0021794 6 0.204
Mouse
multi organism process GO:0051704 134 0.204
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.199
Mouse
multicellular organism growth GO:0035264 4 0.195
mesodermal cell fate commitment GO:0001710 14 0.195
cardiocyte differentiation GO:0035051 44 0.192
regulation of cell death GO:0010941 103 0.191
cell proliferation GO:0008283 80 0.191
Mouse
optomotor response GO:0071632 1 0.189
epidermal cell fate specification GO:0009957 4 0.188
cerebellum morphogenesis GO:0021587 10 0.188
cell projection organization GO:0030030 284 0.187
Mouse
forebrain generation of neurons GO:0021872 14 0.186
Mouse
regulation of gastrulation GO:0010470 24 0.185
mesenchymal cell development GO:0014031 78 0.184
Mouse
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.184
anterior head development GO:0097065 2 0.183
regulation of cell fate specification GO:0042659 20 0.183
positive regulation of rna biosynthetic process GO:1902680 57 0.182
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.182
Fly
aging GO:0007568 2 0.182
optic cup morphogenesis involved in camera type eye development GO:0002072 7 0.180
endodermal cell fate determination GO:0007493 2 0.179
negative regulation of nucleic acid templated transcription GO:1903507 45 0.179
nucleocytoplasmic transport GO:0006913 4 0.177
stem cell fate commitment GO:0048865 1 0.174
protein localization to nucleus GO:0034504 3 0.174
endocrine pancreas development GO:0031018 27 0.174
Zebrafish
limb development GO:0060173 8 0.173
pharyngeal muscle development GO:0043282 4 0.172
mesenchymal cell differentiation GO:0048762 87 0.171
Mouse
pronephric glomerulus development GO:0039021 13 0.169
epithelial tube formation GO:0072175 19 0.169
renal tubule morphogenesis GO:0061333 1 0.167
positive regulation of signal transduction GO:0009967 56 0.167
spinal cord anterior posterior patterning GO:0021512 1 0.164
taxis GO:0042330 109 0.164
Mouse
positive regulation of biosynthetic process GO:0009891 68 0.160
forebrain neuron fate commitment GO:0021877 1 0.160
germ cell migration GO:0008354 8 0.159
endocardium formation GO:0060214 1 0.157
developmental growth GO:0048589 166 0.156
regulation of wnt signaling pathway involved in digestive tract morphogenesis GO:2000056 2 0.154
stem cell development GO:0048864 82 0.154
Mouse
cardiac cell fate commitment GO:0060911 1 0.153
phosphorylation GO:0016310 69 0.153
spinal cord development GO:0021510 46 0.151
Zebrafish
response to other organism GO:0051707 97 0.151
oligodendrocyte development GO:0014003 7 0.151
abducens nucleus development GO:0021742 2 0.148
lateral line ganglion development GO:0048890 2 0.148
eye photoreceptor cell development GO:0042462 30 0.148
nephron development GO:0072006 31 0.147
apoptotic process involved in development GO:1902742 2 0.146
nephric duct morphogenesis GO:0072178 7 0.146
embryonic organ morphogenesis GO:0048562 274 0.146
Mouse
ventral midline development GO:0007418 13 0.144
stem cell proliferation GO:0072089 4 0.142
negative regulation of metabolic process GO:0009892 86 0.141
cardiac muscle tissue development GO:0048738 48 0.141
single organism reproductive process GO:0044702 40 0.137
neural plate development GO:0001840 10 0.137
floor plate development GO:0033504 15 0.136
positive regulation of response to stimulus GO:0048584 80 0.136
somitogenesis GO:0001756 87 0.135
forebrain anterior posterior pattern specification GO:0021797 3 0.135
positive regulation of striated muscle tissue development GO:0045844 1 0.134
epidermal cell differentiation GO:0009913 36 0.133
positive regulation of cell communication GO:0010647 56 0.133
response to organic substance GO:0010033 153 0.133
neural plate morphogenesis GO:0001839 7 0.132
glandular epithelial cell differentiation GO:0002067 9 0.132
Zebrafish
cell proliferation in forebrain GO:0021846 3 0.132
neural plate anterior posterior regionalization GO:0021999 8 0.132
Zebrafish
response to external biotic stimulus GO:0043207 97 0.132
death GO:0016265 121 0.131
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.131
stem cell fate determination GO:0048867 1 0.131
endocardium morphogenesis GO:0003160 4 0.130
central nervous system neuron development GO:0021954 29 0.130
Mouse
neuroepithelial cell differentiation GO:0060563 26 0.130
negative regulation of cell fate commitment GO:0010454 13 0.129
olfactory lobe development GO:0021988 4 0.129
regulation of cardiac muscle tissue development GO:0055024 1 0.129
positive regulation of stem cell proliferation GO:2000648 1 0.128
positive regulation of cell cycle GO:0045787 3 0.128
negative regulation of cellular metabolic process GO:0031324 77 0.127
cerebellum development GO:0021549 17 0.126
Mouse
renal tubule development GO:0061326 5 0.125
defense response GO:0006952 47 0.125
pronephric nephron development GO:0039019 14 0.124
sympathetic nervous system development GO:0048485 3 0.124
embryonic viscerocranium morphogenesis GO:0048703 52 0.123
cell cell signaling involved in cell fate commitment GO:0045168 12 0.123
inner ear receptor cell differentiation GO:0060113 29 0.123
specification of organ identity GO:0010092 2 0.121
regulation of developmental process GO:0050793 247 0.120
Zebrafish Fly
gastrulation with mouth forming second GO:0001702 44 0.120
negative regulation of embryonic development GO:0045992 11 0.120
striated muscle cell development GO:0055002 108 0.120
oligodendrocyte cell fate specification GO:0021778 4 0.118
regulation of wnt signaling pathway calcium modulating pathway GO:0008591 3 0.118
phagocytosis GO:0006909 3 0.117
inner ear receptor cell fate commitment GO:0060120 4 0.116
heart morphogenesis GO:0003007 156 0.116
hormone transport GO:0009914 2 0.116
cellular response to fibroblast growth factor stimulus GO:0044344 22 0.115
bmp signaling pathway involved in heart development GO:0061312 15 0.115
exocrine pancreas development GO:0031017 28 0.114
positive regulation of nervous system development GO:0051962 25 0.114
embryonic eye morphogenesis GO:0048048 30 0.114
pronephros morphogenesis GO:0072114 14 0.114
multicellular organism reproduction GO:0032504 35 0.114
negative regulation of macromolecule metabolic process GO:0010605 76 0.113
programmed cell death GO:0012501 119 0.113
cardiac muscle cell differentiation GO:0055007 30 0.113
t cell differentiation GO:0030217 6 0.110
cell death GO:0008219 121 0.110
forebrain dorsal ventral pattern formation GO:0021798 1 0.110
photoreceptor cell development GO:0042461 40 0.110
neuron neuron synaptic transmission GO:0007270 1 0.109
retinal pigment epithelium development GO:0003406 8 0.108
bone development GO:0060348 14 0.107
striated muscle cell differentiation GO:0051146 129 0.107
convergent extension GO:0060026 118 0.107
hormone secretion GO:0046879 2 0.105
localization of cell GO:0051674 244 0.104
Mouse
neuron development GO:0048666 262 0.102
Mouse
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 0.102
pituitary gland development GO:0021983 16 0.102
negative regulation of stem cell differentiation GO:2000737 2 0.102
muscle cell differentiation GO:0042692 139 0.102
negative regulation of cell fate specification GO:0009996 11 0.102
blood vessel morphogenesis GO:0048514 216 0.101
Mouse
paraxial mesoderm development GO:0048339 8 0.101
vestibular reflex GO:0060005 2 0.100
cell migration involved in gastrulation GO:0042074 79 0.100
tissue regeneration GO:0042246 74 0.099
negative regulation of anterior neural cell fate commitment of the neural plate by wnt signaling pathway GO:0022002 1 0.098
response to biotic stimulus GO:0009607 97 0.097
anterior commissure morphogenesis GO:0021960 3 0.096
neuron death GO:0070997 21 0.095
regulation of stem cell proliferation GO:0072091 2 0.095
spinal cord oligodendrocyte cell fate specification GO:0021530 2 0.094
determination of dorsal identity GO:0048263 13 0.094
regulation of cellular biosynthetic process GO:0031326 245 0.094
Fly
positive regulation of neuron death GO:1901216 1 0.093
cellular response to chemical stimulus GO:0070887 157 0.092
negative regulation of cellular biosynthetic process GO:0031327 55 0.092
gall bladder development GO:0061010 1 0.092
positive regulation of nucleic acid templated transcription GO:1903508 57 0.091
glucose homeostasis GO:0042593 1 0.091
adenohypophysis development GO:0021984 15 0.090
response to hexose GO:0009746 3 0.090
stem cell division GO:0017145 1 0.090
pancreatic d cell differentiation GO:0003311 2 0.089
axon development GO:0061564 166 0.089
Mouse
negative regulation of developmental process GO:0051093 65 0.089
growth GO:0040007 174 0.088
reproduction GO:0000003 40 0.088
regulation of organ growth GO:0046620 3 0.086
positive regulation of muscle tissue development GO:1901863 1 0.085
hatching gland development GO:0048785 3 0.085
regulation of epithelial cell proliferation GO:0050678 3 0.085
embryonic heart tube morphogenesis GO:0003143 108 0.085
gamete generation GO:0007276 33 0.085
dorsal convergence GO:0060030 14 0.084
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.083
limb bud formation GO:0060174 2 0.083
regulation of neuron differentiation GO:0045664 56 0.083
maintenance of location GO:0051235 4 0.083
regulation of cell proliferation GO:0042127 37 0.083
enteric nervous system development GO:0048484 12 0.083
neural plate regionalization GO:0060897 10 0.082
Zebrafish
primary neural tube formation GO:0014020 1 0.081
olfactory bulb development GO:0021772 4 0.081
negative regulation of gastrulation GO:2000542 11 0.081
regulation of fibroblast growth factor receptor signaling pathway GO:0040036 20 0.080
phosphate containing compound metabolic process GO:0006796 108 0.079
cellular protein metabolic process GO:0044267 129 0.079
proximal distal pattern formation GO:0009954 1 0.079
regulation of nervous system development GO:0051960 90 0.079
Fly
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.079
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.079
hemopoiesis GO:0030097 183 0.079
response to endogenous stimulus GO:0009719 83 0.078
regulation of protein catabolic process GO:0042176 1 0.078
stem cell maintenance GO:0019827 4 0.078
embryonic pattern specification GO:0009880 44 0.078
vasculature development GO:0001944 278 0.078
Mouse
kidney morphogenesis GO:0060993 15 0.078
post embryonic morphogenesis GO:0009886 4 0.076
negative regulation of biosynthetic process GO:0009890 55 0.076
kidney epithelium development GO:0072073 23 0.076
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 17 0.075
pancreatic d cell development GO:0003324 1 0.074
hepatocyte proliferation GO:0072574 2 0.074
regulation of intracellular signal transduction GO:1902531 57 0.074
dorsal ventral axis specification GO:0009950 14 0.073
response to fibroblast growth factor GO:0071774 22 0.073
aorta morphogenesis GO:0035909 3 0.072
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.072
positive regulation of cell differentiation GO:0045597 30 0.072
negative regulation of programmed cell death GO:0043069 58 0.071
thrombocyte differentiation GO:0002574 4 0.071
endochondral bone morphogenesis GO:0060350 8 0.071
tissue migration GO:0090130 37 0.071
negative regulation of endodermal cell fate specification GO:0042664 8 0.070
axon extension GO:0048675 45 0.070
endothelial cell fate commitment GO:0060839 3 0.069
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 22 0.069
kupffer s vesicle development GO:0070121 50 0.068
regulation of apoptotic process GO:0042981 98 0.066
protein acetylation GO:0006473 2 0.066
mediolateral intercalation GO:0060031 3 0.065
apoptotic process involved in morphogenesis GO:0060561 2 0.065
canonical wnt signaling pathway involved in heart development GO:0061316 1 0.065
neuroblast fate commitment GO:0014017 1 0.065
regulation of vascular permeability GO:0043114 5 0.065
single organism metabolic process GO:0044710 217 0.065
protein modification process GO:0036211 100 0.064
pronephros development GO:0048793 69 0.064
protein import into nucleus GO:0006606 3 0.064
ion homeostasis GO:0050801 41 0.063
segmentation GO:0035282 97 0.063
regulation of organ morphogenesis GO:2000027 35 0.063
regulation of programmed cell death GO:0043067 101 0.062
mechanoreceptor differentiation GO:0042490 37 0.062
morphogenesis of an epithelial sheet GO:0002011 49 0.061
immune system development GO:0002520 191 0.061

gbx2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.339
reproductive system disease DOID:15 0 0.339