Danio rerio

0 known processes

waslb

Wiskott-Aldrich syndrome-like b

(Aliases: zgc:55478,wasl,MGC55478,zgc:77237)

waslb biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell motility GO:0048870 244 0.212
Zebrafish Worm
morphogenesis of an epithelium GO:0002009 333 0.210
Worm
nucleic acid metabolic process GO:0090304 244 0.197
cell migration GO:0016477 237 0.195
Zebrafish Worm
organic cyclic compound metabolic process GO:1901360 301 0.169
generation of neurons GO:0048699 385 0.166
Fly
positive regulation of transport GO:0051050 2 0.143
Rat
larval development GO:0002164 2 0.137
Worm
regulation of response to stimulus GO:0048583 269 0.126
cellular nitrogen compound metabolic process GO:0034641 290 0.125
negative regulation of cell communication GO:0010648 96 0.121
regulation of metabolic process GO:0019222 359 0.120
Worm
biosynthetic process GO:0009058 294 0.112
negative regulation of biological process GO:0048519 304 0.111
Human Fly
cellular aromatic compound metabolic process GO:0006725 295 0.109
regulation of multicellular organismal process GO:0051239 277 0.102
Fly
heterocycle metabolic process GO:0046483 290 0.100
small molecule metabolic process GO:0044281 77 0.092
regulation of macromolecule biosynthetic process GO:0010556 225 0.090
stem cell proliferation GO:0072089 4 0.089
organic cyclic compound biosynthetic process GO:1901362 223 0.084
regulation of cellular metabolic process GO:0031323 320 0.084
lipid storage GO:0019915 1 0.079
neuron differentiation GO:0030182 353 0.074
Fly
neuron development GO:0048666 262 0.072
Fly
cell surface receptor signaling pathway GO:0007166 325 0.072
nucleocytoplasmic transport GO:0006913 4 0.069
cellular macromolecule metabolic process GO:0044260 391 0.067
regulation of cellular biosynthetic process GO:0031326 245 0.066
negative regulation of protein kinase activity GO:0006469 4 0.066
gene expression GO:0010467 252 0.066
Worm
protein targeting to nucleus GO:0044744 3 0.066
cell morphogenesis GO:0000902 289 0.065
Fly
negative regulation of stem cell differentiation GO:2000737 2 0.064
maintenance of location GO:0051235 4 0.063
nucleobase containing compound metabolic process GO:0006139 274 0.063
regulation of multicellular organismal development GO:2000026 223 0.063
Fly
protein import GO:0017038 3 0.062
cellular component biogenesis GO:0044085 178 0.062
Rat Fly
nitrogen compound metabolic process GO:0006807 319 0.062
organic substance biosynthetic process GO:1901576 289 0.062
aging GO:0007568 2 0.062
blood vessel morphogenesis GO:0048514 216 0.059
signal transduction GO:0007165 455 0.057
rna biosynthetic process GO:0032774 181 0.056
cognition GO:0050890 1 0.056
neuron projection morphogenesis GO:0048812 161 0.055
Fly
organelle localization GO:0051640 49 0.054
Mouse Rat
regulation of neurotransmitter transport GO:0051588 1 0.053
embryonic organ morphogenesis GO:0048562 274 0.053
protein modification process GO:0036211 100 0.053
nuclear transport GO:0051169 4 0.052
regulation of nitrogen compound metabolic process GO:0051171 251 0.052
negative regulation of cellular process GO:0048523 283 0.050
Fly
cellular component assembly GO:0022607 170 0.049
Rat Fly
single organism nuclear import GO:1902593 3 0.049
central nervous system development GO:0007417 387 0.049
macromolecule biosynthetic process GO:0009059 227 0.048
negative regulation of multicellular organismal process GO:0051241 69 0.048
Fly
cellular component movement GO:0006928 335 0.047
Zebrafish Rat Worm Fly
cellular nitrogen compound biosynthetic process GO:0044271 218 0.047
vasculature development GO:0001944 278 0.046
regulation of transcription dna templated GO:0006355 213 0.045
locomotion GO:0040011 313 0.045
Zebrafish Worm
localization of cell GO:0051674 244 0.045
Zebrafish Worm
protein metabolic process GO:0019538 183 0.044
regulation of macromolecule metabolic process GO:0060255 317 0.044
Worm
apical junction assembly GO:0043297 1 0.044
cellular protein modification process GO:0006464 100 0.043
protein phosphorylation GO:0006468 47 0.043
system process GO:0003008 185 0.042
synaptic vesicle transport GO:0048489 1 0.042
nuclear import GO:0051170 3 0.042
cell projection organization GO:0030030 284 0.042
Rat Fly
digestive tract development GO:0048565 265 0.042
heart development GO:0007507 313 0.042
heterocycle biosynthetic process GO:0018130 215 0.041
neuroblast proliferation GO:0007405 2 0.041
establishment of protein localization to organelle GO:0072594 4 0.040
epithelium migration GO:0090132 25 0.040
Worm
protein localization to nucleus GO:0034504 3 0.040
digestive tract morphogenesis GO:0048546 231 0.040
s adenosylmethionine metabolic process GO:0046500 1 0.040
eye development GO:0001654 277 0.039
tube morphogenesis GO:0035239 349 0.038
establishment of epithelial cell polarity GO:0090162 2 0.038
retina development in camera type eye GO:0060041 146 0.038
cytoskeleton organization GO:0007010 96 0.038
Mouse Worm Fly
meiotic nuclear division GO:0007126 4 0.038
negative regulation of macromolecule metabolic process GO:0010605 76 0.037
regulation of cell communication GO:0010646 232 0.037
regulation of multicellular organism growth GO:0040014 4 0.037
single organism metabolic process GO:0044710 217 0.037
regulation of signaling GO:0023051 235 0.037
regulation of signal transduction GO:0009966 225 0.037
regulation of biological quality GO:0065008 263 0.036
Worm Fly
cell part morphogenesis GO:0032990 246 0.036
Fly
protein polymerization GO:0051258 4 0.035
Fly
synaptic vesicle localization GO:0097479 1 0.035
regulation of protein complex assembly GO:0043254 3 0.035
Worm Fly
response to abiotic stimulus GO:0009628 122 0.034
macromolecule modification GO:0043412 111 0.034
ameboidal type cell migration GO:0001667 143 0.034
Worm
segmentation GO:0035282 97 0.034
nucleobase containing compound biosynthetic process GO:0034654 205 0.033
regulation of biosynthetic process GO:0009889 250 0.033
positive regulation of protein complex assembly GO:0031334 2 0.033
Worm Fly
protein import into nucleus GO:0006606 3 0.033
purine containing compound metabolic process GO:0072521 29 0.032
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 2 0.032
establishment of synaptic vesicle localization GO:0097480 1 0.032
regulation of nucleic acid templated transcription GO:1903506 213 0.032
regulation of circadian rhythm GO:0042752 4 0.031
transport GO:0006810 220 0.030
Rat Fly
regulation of cell differentiation GO:0045595 142 0.029
hematopoietic or lymphoid organ development GO:0048534 191 0.029
regulation of neurotransmitter secretion GO:0046928 1 0.029
negative regulation of epithelial cell proliferation GO:0050680 1 0.029
embryonic heart tube development GO:0035050 133 0.028
dorsal motor nucleus of vagus nerve development GO:0021744 4 0.028
negative regulation of response to stimulus GO:0048585 104 0.028
digestive system development GO:0055123 289 0.028
regulation of primary metabolic process GO:0080090 311 0.028
stem cell maintenance GO:0019827 4 0.028
cellular protein metabolic process GO:0044267 129 0.028
cellular amino acid metabolic process GO:0006520 7 0.027
cellular amine metabolic process GO:0044106 2 0.027
adherens junction organization GO:0034332 4 0.027
sensory organ development GO:0007423 393 0.027
Fly
autophagy GO:0006914 4 0.027
growth GO:0040007 174 0.027
Fly
single organism organelle organization GO:1902589 199 0.027
Mouse Worm Fly
carbohydrate derivative metabolic process GO:1901135 61 0.027
medulla oblongata development GO:0021550 4 0.027
aromatic compound biosynthetic process GO:0019438 217 0.026
negative regulation of signaling GO:0023057 96 0.026
membrane lipid biosynthetic process GO:0046467 2 0.025
regulation of dendrite development GO:0050773 3 0.025
cell projection morphogenesis GO:0048858 244 0.025
Fly
regulation of neural precursor cell proliferation GO:2000177 3 0.025
cellular biosynthetic process GO:0044249 286 0.025
regulation of epithelial cell proliferation GO:0050678 3 0.025
establishment or maintenance of polarity of embryonic epithelium GO:0016332 2 0.025
camera type eye development GO:0043010 222 0.025
neurotransmitter secretion GO:0007269 2 0.025
regulation of developmental process GO:0050793 247 0.024
Fly
embryo development ending in birth or egg hatching GO:0009792 271 0.024
Worm
regulation of rna biosynthetic process GO:2001141 213 0.024
regulation of catalytic activity GO:0050790 55 0.024
oxoacid metabolic process GO:0043436 31 0.024
peptidyl serine modification GO:0018209 2 0.024
chordate embryonic development GO:0043009 271 0.024
cellular component morphogenesis GO:0032989 336 0.024
Fly
regulation of gene expression GO:0010468 265 0.023
Worm
organic acid metabolic process GO:0006082 31 0.023
ubiquitin dependent protein catabolic process GO:0006511 3 0.023
regulation of anatomical structure morphogenesis GO:0022603 130 0.023
Fly
neurotransmitter transport GO:0006836 2 0.023
embryonic organ development GO:0048568 381 0.023
regulation of locomotion GO:0040012 55 0.023
Zebrafish
blood vessel development GO:0001568 246 0.023
transcription dna templated GO:0006351 181 0.023
tissue migration GO:0090130 37 0.023
Worm
regulation of stem cell differentiation GO:2000736 4 0.023
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.022
cardiac cell fate commitment GO:0060911 1 0.022
phosphate containing compound metabolic process GO:0006796 108 0.022
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.022
dicarboxylic acid transport GO:0006835 1 0.022
nuclear migration GO:0007097 3 0.022
macromolecular complex subunit organization GO:0043933 74 0.022
Worm Fly
regulation of protein polymerization GO:0032271 2 0.022
Worm Fly
positive regulation of secretion by cell GO:1903532 1 0.021
positive regulation of cellular process GO:0048522 201 0.021
Rat Worm Fly
cellular modified amino acid metabolic process GO:0006575 3 0.021
organelle organization GO:0006996 227 0.021
Mouse Rat Worm Fly
positive regulation of protein polymerization GO:0032273 2 0.021
Worm Fly
guanosine containing compound metabolic process GO:1901068 4 0.021
nucleic acid templated transcription GO:0097659 181 0.021
gastrulation GO:0007369 208 0.021
regulation of molecular function GO:0065009 70 0.021
cortical actin cytoskeleton organization GO:0030866 1 0.020
regulation of cellular ketone metabolic process GO:0010565 7 0.020
developmental growth GO:0048589 166 0.020
Fly
regulation of protein import into nucleus GO:0042306 2 0.020
positive regulation of nucleic acid templated transcription GO:1903508 57 0.020
rna metabolic process GO:0016070 219 0.020
establishment of organelle localization GO:0051656 45 0.020
Rat
regulation of cellular protein metabolic process GO:0032268 52 0.020
establishment of cell polarity GO:0030010 18 0.020
response to stress GO:0006950 263 0.020
transcription from rna polymerase ii promoter GO:0006366 80 0.020
macromolecular complex disassembly GO:0032984 1 0.020
regulation of wnt signaling pathway GO:0030111 53 0.020
negative regulation of cellular metabolic process GO:0031324 77 0.019
cytokinesis GO:0000910 3 0.019
regulation of rna metabolic process GO:0051252 224 0.019
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.019
response to xenobiotic stimulus GO:0009410 45 0.019
positive regulation of cell adhesion GO:0045785 1 0.019
muscle organ development GO:0007517 101 0.019
Fly
amine metabolic process GO:0009308 2 0.019
gastrulation with mouth forming second GO:0001702 44 0.019
negative regulation of signal transduction GO:0009968 94 0.019
stem cell differentiation GO:0048863 117 0.019
negative regulation of defense response GO:0031348 2 0.019
regulation of cellular amino acid metabolic process GO:0006521 0 0.019
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.019
exocytosis GO:0006887 1 0.019
regulation of cell shape GO:0008360 1 0.019
Fly
organonitrogen compound metabolic process GO:1901564 74 0.018
neural precursor cell proliferation GO:0061351 20 0.018
gtp metabolic process GO:0046039 4 0.018
maternal determination of anterior posterior axis embryo GO:0008358 4 0.018
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.018
Fly
glycoprotein biosynthetic process GO:0009101 21 0.018
axon development GO:0061564 166 0.018
Fly
regulation of dna templated transcription in response to stress GO:0043620 0 0.018
neuron projection development GO:0031175 180 0.018
Fly
convergent extension GO:0060026 118 0.018
amino acid transport GO:0006865 2 0.018
cell fate commitment GO:0045165 99 0.017
positive regulation of macromolecule metabolic process GO:0010604 93 0.017
regulation of nucleotide catabolic process GO:0030811 2 0.017
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.017
angiogenesis GO:0001525 158 0.017
neurological system process GO:0050877 62 0.017
establishment of localization GO:0051234 244 0.017
Rat Fly
positive regulation of cellular catabolic process GO:0031331 3 0.017
regulation of protein phosphorylation GO:0001932 18 0.017
rna localization GO:0006403 4 0.017
dna templated transcription elongation GO:0006354 3 0.017
adult behavior GO:0030534 2 0.017
ribose phosphate metabolic process GO:0019693 27 0.017
axonogenesis GO:0007409 152 0.017
Fly
microtubule based process GO:0007017 60 0.017
Fly
neural tube development GO:0021915 62 0.016
negative regulation of kinase activity GO:0033673 4 0.016
multicellular organism growth GO:0035264 4 0.016
regulation of reproductive process GO:2000241 4 0.016
cellular cation homeostasis GO:0030003 17 0.016
meiotic cell cycle process GO:1903046 3 0.016
vesicle localization GO:0051648 27 0.016
Rat
positive regulation of cytoskeleton organization GO:0051495 3 0.016
Worm Fly
heart looping GO:0001947 94 0.016
positive regulation of catabolic process GO:0009896 4 0.015
regulation of cellular component movement GO:0051270 55 0.015
Zebrafish
regulation of cell migration GO:0030334 40 0.015
Zebrafish
positive regulation of cellular component biogenesis GO:0044089 3 0.015
Rat Worm Fly
alpha amino acid metabolic process GO:1901605 3 0.015
regulation of cellular amine metabolic process GO:0033238 0 0.015
negative regulation of metabolic process GO:0009892 86 0.015
cell cell signaling GO:0007267 52 0.015
Fly
cell cycle GO:0007049 93 0.015
Mouse
regulation of cell development GO:0060284 100 0.015
wnt signaling pathway GO:0016055 80 0.015
establishment or maintenance of cell polarity GO:0007163 29 0.015
cellular response to extracellular stimulus GO:0031668 2 0.015
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.015
response to chemical GO:0042221 320 0.015
Zebrafish
regulation of protein targeting GO:1903533 2 0.015
regulation of protein catabolic process GO:0042176 1 0.015
regulation of protein metabolic process GO:0051246 56 0.014
mesenchymal cell differentiation GO:0048762 87 0.014
estrogen metabolic process GO:0008210 2 0.014
negative regulation of cellular biosynthetic process GO:0031327 55 0.014
metal ion homeostasis GO:0055065 26 0.014
morphogenesis of an epithelial sheet GO:0002011 49 0.014
positive regulation of gene expression GO:0010628 71 0.014
sensory system development GO:0048880 76 0.014
organelle assembly GO:0070925 110 0.014
cell cell junction maintenance GO:0045217 1 0.014
cytoskeleton dependent cytokinesis GO:0061640 3 0.014
regulation of cellular component organization GO:0051128 86 0.014
Human Rat Worm Fly
small gtpase mediated signal transduction GO:0007264 8 0.013
cellular homeostasis GO:0019725 26 0.013
regulation of establishment of protein localization GO:0070201 4 0.013
phosphorylation GO:0016310 69 0.013
epithelial tube morphogenesis GO:0060562 148 0.013
cellular response to chemical stimulus GO:0070887 157 0.013
Zebrafish
cellular ketone metabolic process GO:0042180 11 0.013
phosphorus metabolic process GO:0006793 109 0.013
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.013
intracellular signal transduction GO:0035556 85 0.013
regulation of purine nucleotide catabolic process GO:0033121 2 0.013
sensory organ morphogenesis GO:0090596 200 0.013
cell projection assembly GO:0030031 64 0.013
Rat
determination of bilateral symmetry GO:0009855 204 0.013
meiotic chromosome segregation GO:0045132 3 0.013
detection of external stimulus GO:0009581 24 0.013
cell cell junction organization GO:0045216 10 0.013
regulation of protein transport GO:0051223 3 0.013
response to external stimulus GO:0009605 264 0.013
Zebrafish Mouse
inner ear development GO:0048839 126 0.013
golgi vesicle transport GO:0048193 3 0.012
stem cell division GO:0017145 1 0.012
regulation of nucleocytoplasmic transport GO:0046822 2 0.012
developmental growth involved in morphogenesis GO:0060560 86 0.012
regulation of epidermis development GO:0045682 2 0.012
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.012
regulation of gtpase activity GO:0043087 2 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.012
oocyte anterior posterior axis specification GO:0007314 4 0.012
carboxylic acid metabolic process GO:0019752 22 0.012
cilium organization GO:0044782 71 0.012
morphogenesis of follicular epithelium GO:0016333 1 0.012
cation homeostasis GO:0055080 33 0.012
regionalization GO:0003002 274 0.012
Fly
protein complex disassembly GO:0043241 1 0.012
lateral line system development GO:0048925 76 0.012
lateral line development GO:0048882 66 0.012
mitotic cytokinesis GO:0000281 3 0.012
proximal distal pattern formation GO:0009954 1 0.012
regulation of mrna processing GO:0050684 3 0.011
cellular component maintenance GO:0043954 3 0.011
cellular macromolecule biosynthetic process GO:0034645 224 0.011
cardiac conduction GO:0061337 3 0.011
regulation of neurogenesis GO:0050767 87 0.011
cell junction organization GO:0034330 11 0.011
actin filament based process GO:0030029 64 0.011
Mouse Rat Worm Fly
regulation of organ growth GO:0046620 3 0.011
regulation of intracellular protein transport GO:0033157 3 0.011
guanosine containing compound catabolic process GO:1901069 2 0.011
embryonic skeletal system morphogenesis GO:0048704 93 0.011
cell substrate adhesion GO:0031589 4 0.011
actin filament organization GO:0007015 15 0.011
Worm Fly
negative regulation of programmed cell death GO:0043069 58 0.011
determination of heart left right asymmetry GO:0061371 117 0.011
cellular response to external stimulus GO:0071496 2 0.011
neuromast development GO:0048884 46 0.011
morphogenesis of an epithelial fold GO:0060571 1 0.011
cellular component disassembly GO:0022411 1 0.011
positive regulation of biological process GO:0048518 253 0.011
Rat Worm Fly
positive regulation of nucleotide catabolic process GO:0030813 1 0.011
protein localization GO:0008104 40 0.011
Mouse Fly
negative regulation of mapk cascade GO:0043409 4 0.011
directional locomotion GO:0033058 1 0.011
cell adhesion GO:0007155 40 0.010
negative regulation of developmental process GO:0051093 65 0.010
Fly
ion homeostasis GO:0050801 41 0.010
regulation of cell projection assembly GO:0060491 4 0.010
Rat
positive regulation of secretion GO:0051047 1 0.010
peptide metabolic process GO:0006518 1 0.010
regulation of dna templated transcription elongation GO:0032784 3 0.010
biological adhesion GO:0022610 40 0.010
specification of symmetry GO:0009799 204 0.010
nucleic acid transport GO:0050657 2 0.010
hemopoiesis GO:0030097 183 0.010

waslb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.050
cardiovascular system disease DOID:1287 0 0.019
disease of metabolism DOID:0014667 0 0.017
inherited metabolic disorder DOID:655 0 0.015
nervous system disease DOID:863 0 0.012
myopathy DOID:423 0 0.010
muscular disease DOID:0080000 0 0.010
musculoskeletal system disease DOID:17 0 0.010
muscle tissue disease DOID:66 0 0.010