Danio rerio

0 known processes

ddx6

DEAD (Asp-Glu-Ala-Asp) box polypeptide 6

(Aliases: si:ch211-147p17.1)

ddx6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
aging GO:0007568 2 0.415
aromatic compound biosynthetic process GO:0019438 217 0.341
cognition GO:0050890 1 0.328
negative regulation of cellular process GO:0048523 283 0.285
cellular macromolecule metabolic process GO:0044260 391 0.229
autophagy GO:0006914 4 0.188
positive regulation of exocytosis GO:0045921 1 0.178
rna biosynthetic process GO:0032774 181 0.166
establishment of protein localization to organelle GO:0072594 4 0.156
larval development GO:0002164 2 0.135
meiotic chromosome segregation GO:0045132 3 0.125
spindle assembly GO:0051225 2 0.103
regulation of rna biosynthetic process GO:2001141 213 0.102
regulation of protein targeting GO:1903533 2 0.094
regulation of establishment of protein localization GO:0070201 4 0.093
protein targeting to nucleus GO:0044744 3 0.090
cellular macromolecule biosynthetic process GO:0034645 224 0.084
regulation of rna metabolic process GO:0051252 224 0.084
regulation of nucleic acid templated transcription GO:1903506 213 0.077
regulation of protein localization to nucleus GO:1900180 2 0.073
single organism nuclear import GO:1902593 3 0.073
regulation of muscle contraction GO:0006937 3 0.072
protein dealkylation GO:0008214 2 0.068
nucleocytoplasmic transport GO:0006913 4 0.068
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.067
protein localization to nucleus GO:0034504 3 0.066
macromolecule biosynthetic process GO:0009059 227 0.065
cellular protein metabolic process GO:0044267 129 0.065
regulation of cellular metabolic process GO:0031323 320 0.064
rna metabolic process GO:0016070 219 0.062
negative regulation of protein transport GO:0051224 3 0.061
maintenance of location GO:0051235 4 0.061
nucleobase containing compound metabolic process GO:0006139 274 0.061
negative regulation of biological process GO:0048519 304 0.060
organic cyclic compound biosynthetic process GO:1901362 223 0.059
negative regulation of protein localization to nucleus GO:1900181 2 0.058
endosomal transport GO:0016197 2 0.058
nuclear transport GO:0051169 4 0.057
regulation of biological quality GO:0065008 263 0.056
transcription dna templated GO:0006351 181 0.053
macromolecular complex subunit organization GO:0043933 74 0.053
cellular component assembly GO:0022607 170 0.052
organelle assembly GO:0070925 110 0.052
positive regulation of secretion by cell GO:1903532 1 0.051
protein import into nucleus GO:0006606 3 0.051
viral process GO:0016032 1 0.051
positive regulation of muscle cell differentiation GO:0051149 1 0.051
protein import GO:0017038 3 0.050
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.050
protein demethylation GO:0006482 2 0.050
regulation of autophagy GO:0010506 3 0.050
positive regulation of biological process GO:0048518 253 0.048
regulation of exocytosis GO:0017157 1 0.048
regulation of gene expression GO:0010468 265 0.048
vacuolar transport GO:0007034 2 0.047
regulation of biosynthetic process GO:0009889 250 0.046
cellular aromatic compound metabolic process GO:0006725 295 0.046
biosynthetic process GO:0009058 294 0.046
organelle organization GO:0006996 227 0.046
lipid storage GO:0019915 1 0.046
regulation of response to nutrient levels GO:0032107 1 0.045
olfactory bulb development GO:0021772 4 0.044
regulation of nitrogen compound metabolic process GO:0051171 251 0.044
regulation of protein transport GO:0051223 3 0.044
cellular nitrogen compound metabolic process GO:0034641 290 0.044
organic substance biosynthetic process GO:1901576 289 0.043
nuclear import GO:0051170 3 0.043
regulation of primary metabolic process GO:0080090 311 0.043
protein metabolic process GO:0019538 183 0.042
stem cell maintenance GO:0019827 4 0.042
regulation of protein import into nucleus GO:0042306 2 0.042
cellular protein modification process GO:0006464 100 0.042
heterocycle biosynthetic process GO:0018130 215 0.040
negative regulation of cellular biosynthetic process GO:0031327 55 0.040
neurological system process GO:0050877 62 0.040
single organism metabolic process GO:0044710 217 0.040
regulation of cell cycle GO:0051726 52 0.039
protein secretion GO:0009306 1 0.038
golgi vesicle transport GO:0048193 3 0.038
positive regulation of transport GO:0051050 2 0.038
regulation of cell projection assembly GO:0060491 4 0.038
cellular response to chemical stimulus GO:0070887 157 0.038
death GO:0016265 121 0.037
lamellipodium organization GO:0097581 1 0.037
microtubule based process GO:0007017 60 0.037
cellular component biogenesis GO:0044085 178 0.037
nucleobase containing compound biosynthetic process GO:0034654 205 0.036
organic cyclic compound metabolic process GO:1901360 301 0.036
rna localization GO:0006403 4 0.036
negative regulation of nucleic acid templated transcription GO:1903507 45 0.036
positive regulation of secretion GO:0051047 1 0.035
cellular ketone metabolic process GO:0042180 11 0.035
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.034
negative regulation of cytoplasmic transport GO:1903650 2 0.033
histone demethylation GO:0016577 2 0.033
regulation of intracellular protein transport GO:0033157 3 0.033
oxoacid metabolic process GO:0043436 31 0.033
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.033
regulation of transcription dna templated GO:0006355 213 0.033
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.032
cellular carbohydrate metabolic process GO:0044262 4 0.032
regulation of cardiac muscle contraction GO:0055117 2 0.032
negative regulation of intracellular transport GO:0032387 3 0.032
regulation of macromolecule biosynthetic process GO:0010556 225 0.032
meiotic cell cycle process GO:1903046 3 0.031
histone lysine demethylation GO:0070076 2 0.031
regulation of cytoplasmic transport GO:1903649 4 0.031
regulation of nucleocytoplasmic transport GO:0046822 2 0.031
protein modification process GO:0036211 100 0.031
positive regulation of cellular process GO:0048522 201 0.030
muscle structure development GO:0061061 196 0.030
histone h3 k9 demethylation GO:0033169 2 0.030
signal transduction GO:0007165 455 0.029
central nervous system development GO:0007417 387 0.029
organophosphate biosynthetic process GO:0090407 23 0.029
protein dephosphorylation GO:0006470 3 0.029
nucleic acid metabolic process GO:0090304 244 0.029
single organism localization GO:1902578 225 0.029
cellular response to lipopolysaccharide GO:0071222 3 0.029
tube morphogenesis GO:0035239 349 0.028
small molecule metabolic process GO:0044281 77 0.027
nitrogen compound metabolic process GO:0006807 319 0.027
meiotic nuclear division GO:0007126 4 0.026
cellular component morphogenesis GO:0032989 336 0.026
membrane invagination GO:0010324 1 0.026
multicellular organism growth GO:0035264 4 0.026
chromosome segregation GO:0007059 12 0.026
multi organism cellular process GO:0044764 2 0.026
exocytosis GO:0006887 1 0.026
negative regulation of protein kinase activity GO:0006469 4 0.025
heterocycle metabolic process GO:0046483 290 0.025
locomotor rhythm GO:0045475 3 0.025
positive regulation of neuron apoptotic process GO:0043525 1 0.025
negative regulation of metabolic process GO:0009892 86 0.024
enzyme linked receptor protein signaling pathway GO:0007167 106 0.024
response to abiotic stimulus GO:0009628 122 0.024
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.024
ear development GO:0043583 127 0.024
antimicrobial humoral response GO:0019730 2 0.023
single organism organelle organization GO:1902589 199 0.023
regulation of multicellular organism growth GO:0040014 4 0.023
cell cycle GO:0007049 93 0.023
regulation of glial cell differentiation GO:0045685 4 0.023
positive regulation of cell cycle GO:0045787 3 0.023
negative regulation of protein phosphorylation GO:0001933 4 0.023
regulation of macromolecule metabolic process GO:0060255 317 0.023
response to biotic stimulus GO:0009607 97 0.023
cellular biosynthetic process GO:0044249 286 0.023
cellular amino acid metabolic process GO:0006520 7 0.023
negative regulation of biosynthetic process GO:0009890 55 0.022
organic acid metabolic process GO:0006082 31 0.022
gene expression GO:0010467 252 0.022
regulation of response to stimulus GO:0048583 269 0.022
convergent extension GO:0060026 118 0.022
regulation of reactive oxygen species metabolic process GO:2000377 2 0.022
er nucleus signaling pathway GO:0006984 2 0.022
protein heterooligomerization GO:0051291 1 0.022
negative regulation of protein import into nucleus GO:0042308 2 0.022
carbohydrate metabolic process GO:0005975 12 0.021
heart contraction GO:0060047 71 0.021
extrinsic apoptotic signaling pathway GO:0097191 3 0.021
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.021
macromolecule modification GO:0043412 111 0.021
cellular component movement GO:0006928 335 0.021
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.021
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.021
modification of morphology or physiology of other organism GO:0035821 4 0.021
head development GO:0060322 303 0.020
organonitrogen compound metabolic process GO:1901564 74 0.020
negative regulation of multicellular organismal process GO:0051241 69 0.020
regulation of neurological system process GO:0031644 2 0.020
muscle tissue development GO:0060537 110 0.020
guanosine containing compound catabolic process GO:1901069 2 0.020
cellular response to biotic stimulus GO:0071216 3 0.020
phosphate containing compound metabolic process GO:0006796 108 0.019
striated muscle cell development GO:0055002 108 0.019
alternative mrna splicing via spliceosome GO:0000380 1 0.019
lysosomal transport GO:0007041 2 0.019
cell death GO:0008219 121 0.019
response to chemical GO:0042221 320 0.019
negative regulation of kinase activity GO:0033673 4 0.019
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.018
detection of mechanical stimulus involved in sensory perception GO:0050974 11 0.018
regulation of skeletal muscle fiber development GO:0048742 2 0.018
programmed cell death GO:0012501 119 0.018
nucleic acid templated transcription GO:0097659 181 0.018
positive regulation of transcription dna templated GO:0045893 57 0.018
cellular response to organic substance GO:0071310 105 0.018
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.018
regulation of biomineral tissue development GO:0070167 2 0.018
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.018
morphogenesis of an epithelium GO:0002009 333 0.018
somatic muscle development GO:0007525 4 0.018
striated muscle tissue development GO:0014706 110 0.018
odontogenesis of dentin containing tooth GO:0042475 1 0.018
tissue remodeling GO:0048771 4 0.018
system process GO:0003008 185 0.018
nucleobase containing compound transport GO:0015931 2 0.018
regulation of cellular amine metabolic process GO:0033238 0 0.017
transcription from rna polymerase ii promoter GO:0006366 80 0.017
response to external biotic stimulus GO:0043207 97 0.017
cell migration GO:0016477 237 0.017
cell cycle g1 s phase transition GO:0044843 1 0.017
cellular component disassembly GO:0022411 1 0.017
regulation of system process GO:0044057 40 0.017
interspecies interaction between organisms GO:0044419 4 0.017
neuron neuron synaptic transmission GO:0007270 1 0.017
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.017
osteoclast differentiation GO:0030316 1 0.017
bmp signaling pathway GO:0030509 52 0.017
negative regulation of developmental process GO:0051093 65 0.017
regulation of synaptic plasticity GO:0048167 1 0.017
regulation of filopodium assembly GO:0051489 2 0.017
cell surface receptor signaling pathway GO:0007166 325 0.017
catabolic process GO:0009056 32 0.017
nucleic acid transport GO:0050657 2 0.016
regulation of myelination GO:0031641 1 0.016
digestive tract morphogenesis GO:0048546 231 0.016
synaptic vesicle localization GO:0097479 1 0.016
regulation of metabolic process GO:0019222 359 0.016
establishment of protein localization to vacuole GO:0072666 1 0.016
regulation of oligodendrocyte differentiation GO:0048713 1 0.016
inner ear development GO:0048839 126 0.016
cell cycle process GO:0022402 53 0.016
multicellular organismal signaling GO:0035637 22 0.016
cellular amine metabolic process GO:0044106 2 0.016
response to organic substance GO:0010033 153 0.016
neuron development GO:0048666 262 0.016
synaptic vesicle recycling GO:0036465 1 0.016
peptidyl serine phosphorylation GO:0018105 1 0.016
establishment of localization GO:0051234 244 0.016
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 4 0.016
heart development GO:0007507 313 0.016
regulation of signaling GO:0023051 235 0.016
positive regulation of glial cell differentiation GO:0045687 1 0.016
blood vessel development GO:0001568 246 0.016
single organism transport GO:0044765 206 0.016
microtubule organizing center organization GO:0031023 1 0.016
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.016
actin polymerization or depolymerization GO:0008154 2 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.015
immune system process GO:0002376 241 0.015
carboxylic acid metabolic process GO:0019752 22 0.015
digestive system development GO:0055123 289 0.015
regulation of striated muscle contraction GO:0006942 2 0.015
regulation of binding GO:0051098 3 0.015
positive regulation of response to stimulus GO:0048584 80 0.015
regulation of protein complex assembly GO:0043254 3 0.015
cellular localization GO:0051641 97 0.015
proteasomal protein catabolic process GO:0010498 2 0.015
negative regulation of signal transduction GO:0009968 94 0.015
lipid metabolic process GO:0006629 52 0.015
adult behavior GO:0030534 2 0.015
negative regulation of intracellular protein transport GO:0090317 3 0.015
regulation of cellular biosynthetic process GO:0031326 245 0.015
cellular catabolic process GO:0044248 27 0.015
blood circulation GO:0008015 87 0.015
neuromuscular process controlling balance GO:0050885 3 0.015
negative regulation of cellular catabolic process GO:0031330 3 0.015
stem cell division GO:0017145 1 0.015
cellular response to topologically incorrect protein GO:0035967 2 0.015
regulation of dna replication GO:0006275 3 0.014
spermatid development GO:0007286 2 0.014
regulation of stem cell differentiation GO:2000736 4 0.014
immune system development GO:0002520 191 0.014
cellular lipid metabolic process GO:0044255 36 0.014
sensory organ development GO:0007423 393 0.014
negative regulation of catalytic activity GO:0043086 21 0.014
intestinal epithelial cell differentiation GO:0060575 3 0.014
regulation of signal transduction GO:0009966 225 0.014
regulation of posttranscriptional gene silencing GO:0060147 1 0.014
regionalization GO:0003002 274 0.014
regulation of skeletal muscle tissue development GO:0048641 4 0.014
heart process GO:0003015 71 0.014
regulation of protein catabolic process GO:0042176 1 0.014
cell motility GO:0048870 244 0.014
skeletal muscle tissue development GO:0007519 67 0.014
muscle cell development GO:0055001 115 0.014
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.014
positive regulation of cellular component biogenesis GO:0044089 3 0.013
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.013
embryonic organ development GO:0048568 381 0.013
cell projection organization GO:0030030 284 0.013
post golgi vesicle mediated transport GO:0006892 1 0.013
rna transport GO:0050658 2 0.013
positive regulation of striated muscle tissue development GO:0045844 1 0.013
regulation of neurotransmitter secretion GO:0046928 1 0.013
negative regulation of catabolic process GO:0009895 3 0.013
negative regulation of cellular metabolic process GO:0031324 77 0.013
positive regulation of immune effector process GO:0002699 3 0.013
calcium ion transport into cytosol GO:0060402 3 0.013
regulation of dendrite development GO:0050773 3 0.013
cytokinesis GO:0000910 3 0.013
digestive tract development GO:0048565 265 0.013
female meiotic division GO:0007143 2 0.013
regulation of multicellular organismal development GO:2000026 223 0.013
chromosome organization GO:0051276 31 0.013
peptide transport GO:0015833 1 0.013
convergent extension involved in gastrulation GO:0060027 71 0.013
muscle cell differentiation GO:0042692 139 0.013
positive regulation of gliogenesis GO:0014015 2 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
activation of mapk activity GO:0000187 3 0.013
neuron differentiation GO:0030182 353 0.012
sequestering of metal ion GO:0051238 3 0.012
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.012
cellular component assembly involved in morphogenesis GO:0010927 107 0.012
photoreceptor cell differentiation GO:0046530 55 0.012
regulation of protein binding GO:0043393 3 0.012
cellular response to molecule of bacterial origin GO:0071219 3 0.012
phosphorylation GO:0016310 69 0.012
gtp metabolic process GO:0046039 4 0.012
regulation of lipid transport GO:0032368 4 0.012
single fertilization GO:0007338 3 0.012
establishment of localization in cell GO:0051649 77 0.012
microtubule cytoskeleton organization GO:0000226 33 0.012
regulation of erythrocyte differentiation GO:0045646 2 0.012
mucopolysaccharide metabolic process GO:1903510 2 0.012
regulation of bmp signaling pathway GO:0030510 39 0.012
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.012
amine metabolic process GO:0009308 2 0.012
regulation of hormone secretion GO:0046883 2 0.012
heart morphogenesis GO:0003007 156 0.012
embryonic limb morphogenesis GO:0030326 2 0.012
chromatin organization GO:0006325 22 0.012
cellular nitrogen compound biosynthetic process GO:0044271 218 0.012
regulation of response to extracellular stimulus GO:0032104 1 0.012
negative regulation of signaling GO:0023057 96 0.012
eye development GO:0001654 277 0.012
multicellular organismal response to stress GO:0033555 2 0.011
cell aging GO:0007569 2 0.011
calcium mediated signaling GO:0019722 2 0.011
negative regulation of rna biosynthetic process GO:1902679 45 0.011
regulation of programmed cell death GO:0043067 101 0.011
chemosensory behavior GO:0007635 1 0.011
cellular response to extracellular stimulus GO:0031668 2 0.011
generation of neurons GO:0048699 385 0.011
developmental maturation GO:0021700 34 0.011
forebrain cell migration GO:0021885 1 0.011
positive regulation of nucleic acid templated transcription GO:1903508 57 0.011
muscle organ development GO:0007517 101 0.011
protein phosphorylation GO:0006468 47 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.011
regulation of cellular ketone metabolic process GO:0010565 7 0.011
regulation of cell development GO:0060284 100 0.011
dna templated transcription elongation GO:0006354 3 0.011
endosome organization GO:0007032 2 0.011
regulation of protein metabolic process GO:0051246 56 0.011
response to unfolded protein GO:0006986 2 0.011
regulation of postsynaptic membrane potential GO:0060078 1 0.011
regulation of cell activation GO:0050865 1 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.011
regulation of myotube differentiation GO:0010830 2 0.011
positive regulation of dna templated transcription elongation GO:0032786 1 0.011
interaction with host GO:0051701 4 0.011
centrosome cycle GO:0007098 1 0.011
modification dependent protein catabolic process GO:0019941 3 0.011
negative regulation of cell communication GO:0010648 96 0.011
regulation of receptor activity GO:0010469 2 0.011
circadian sleep wake cycle sleep GO:0050802 1 0.011
positive regulation of epithelial cell proliferation GO:0050679 1 0.011
cartilage development GO:0051216 96 0.011
regulation of transporter activity GO:0032409 2 0.011
synapsis GO:0007129 1 0.011
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.011
positive regulation of cell division GO:0051781 2 0.011
myeloid cell differentiation GO:0030099 86 0.011
regulation of cell shape GO:0008360 1 0.011
vasculature development GO:0001944 278 0.011
regulation of nervous system development GO:0051960 90 0.011
dorsal ventral pattern formation GO:0009953 125 0.011
rna export from nucleus GO:0006405 1 0.010
homeostatic process GO:0042592 142 0.010
fertilization GO:0009566 3 0.010
circadian sleep wake cycle GO:0042745 2 0.010
regulation of calcium ion transport GO:0051924 2 0.010
determination of left right symmetry GO:0007368 179 0.010
response to drug GO:0042493 3 0.010
carbohydrate homeostasis GO:0033500 1 0.010
positive regulation of cell activation GO:0050867 1 0.010
positive regulation of myeloid cell differentiation GO:0045639 2 0.010
cellular protein catabolic process GO:0044257 4 0.010
cell morphogenesis GO:0000902 289 0.010
establishment of synaptic vesicle localization GO:0097480 1 0.010
neural crest formation GO:0014029 14 0.010
myeloid cell development GO:0061515 32 0.010
transport GO:0006810 220 0.010
membrane fusion GO:0061025 2 0.010
insulin like growth factor receptor signaling pathway GO:0048009 4 0.010
regulation of cellular protein catabolic process GO:1903362 1 0.010
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.010
multicellular organismal metabolic process GO:0044236 2 0.010
mrna stabilization GO:0048255 4 0.010
g1 s transition of mitotic cell cycle GO:0000082 1 0.010
cardiocyte differentiation GO:0035051 44 0.010
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.010
response to glucose GO:0009749 3 0.010
peptidyl serine modification GO:0018209 2 0.010

ddx6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.035
central nervous system disease DOID:331 0 0.023
neurodegenerative disease DOID:1289 0 0.023
nervous system disease DOID:863 0 0.023
cancer DOID:162 0 0.016
disease of cellular proliferation DOID:14566 0 0.016
organ system cancer DOID:0050686 0 0.014