Danio rerio

34 known processes

nrf1

nuclear respiratory factor 1

(Aliases: ube2h,SC:bZ3C13.2,SC:BZ3C13.1)

nrf1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
eye development GO:0001654 277 0.640
sensory organ development GO:0007423 393 0.437
cellular nitrogen compound metabolic process GO:0034641 290 0.359
Fly
nitrogen compound metabolic process GO:0006807 319 0.308
Fly
embryo development ending in birth or egg hatching GO:0009792 271 0.295
biosynthetic process GO:0009058 294 0.280
Fly
neuron differentiation GO:0030182 353 0.263
regulation of macromolecule metabolic process GO:0060255 317 0.238
Fly
response to stress GO:0006950 263 0.236
aromatic compound biosynthetic process GO:0019438 217 0.232
Fly
regulation of multicellular organismal process GO:0051239 277 0.218
Fly
generation of neurons GO:0048699 385 0.193
negative regulation of biological process GO:0048519 304 0.189
Fly
chordate embryonic development GO:0043009 271 0.182
regulation of nitrogen compound metabolic process GO:0051171 251 0.180
Fly
camera type eye development GO:0043010 222 0.180
eye morphogenesis GO:0048592 144 0.179
positive regulation of biological process GO:0048518 253 0.172
Fly
larval development GO:0002164 2 0.160
skeletal system development GO:0001501 181 0.150
nucleic acid metabolic process GO:0090304 244 0.145
Fly
meiotic nuclear division GO:0007126 4 0.142
regulation of metabolic process GO:0019222 359 0.140
Fly
sensory organ morphogenesis GO:0090596 200 0.138
nucleobase containing compound metabolic process GO:0006139 274 0.133
Fly
regulation of developmental process GO:0050793 247 0.130
Fly
cellular aromatic compound metabolic process GO:0006725 295 0.125
Fly
protein metabolic process GO:0019538 183 0.124
regulation of biological quality GO:0065008 263 0.119
cellular macromolecule metabolic process GO:0044260 391 0.118
Fly
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.117
positive regulation of metabolic process GO:0009893 108 0.116
rna metabolic process GO:0016070 219 0.116
Fly
multicellular organism growth GO:0035264 4 0.115
cellular nitrogen compound biosynthetic process GO:0044271 218 0.113
Fly
neuron development GO:0048666 262 0.112
digestive tract development GO:0048565 265 0.109
retina development in camera type eye GO:0060041 146 0.105
heterocycle metabolic process GO:0046483 290 0.104
Fly
organic substance biosynthetic process GO:1901576 289 0.101
Fly
cell part morphogenesis GO:0032990 246 0.095
brain development GO:0007420 293 0.095
gene expression GO:0010467 252 0.095
Fly
response to chemical GO:0042221 320 0.094
locomotion GO:0040011 313 0.094
regulation of multicellular organism growth GO:0040014 4 0.093
cell surface receptor signaling pathway GO:0007166 325 0.092
Fly
morphogenesis of an epithelium GO:0002009 333 0.090
digestive system development GO:0055123 289 0.087
cellular macromolecule biosynthetic process GO:0034645 224 0.086
Fly
cell morphogenesis GO:0000902 289 0.085
positive regulation of cellular process GO:0048522 201 0.083
Fly
organic cyclic compound metabolic process GO:1901360 301 0.081
Fly
nucleic acid templated transcription GO:0097659 181 0.080
Fly
embryonic organ morphogenesis GO:0048562 274 0.079
chromosome organization GO:0051276 31 0.079
cell migration GO:0016477 237 0.076
regulation of primary metabolic process GO:0080090 311 0.073
Fly
nucleobase containing compound biosynthetic process GO:0034654 205 0.072
Fly
striated muscle cell differentiation GO:0051146 129 0.071
mesoderm development GO:0007498 88 0.070
cellular biosynthetic process GO:0044249 286 0.069
Fly
tube morphogenesis GO:0035239 349 0.068
cellular component morphogenesis GO:0032989 336 0.068
response to abiotic stimulus GO:0009628 122 0.065
signal transduction GO:0007165 455 0.062
Fly
regionalization GO:0003002 274 0.060
cellular component movement GO:0006928 335 0.058
regulation of cellular metabolic process GO:0031323 320 0.056
Fly
single organism localization GO:1902578 225 0.056
retina morphogenesis in camera type eye GO:0060042 79 0.056
regulation of transcription dna templated GO:0006355 213 0.054
Fly
organic cyclic compound biosynthetic process GO:1901362 223 0.052
Fly
embryonic organ development GO:0048568 381 0.052
negative regulation of cellular process GO:0048523 283 0.051
Fly
blood vessel development GO:0001568 246 0.051
single organism metabolic process GO:0044710 217 0.049
response to uv GO:0009411 3 0.049
regulation of multicellular organismal development GO:2000026 223 0.049
Fly
regulation of rna metabolic process GO:0051252 224 0.048
Fly
muscle structure development GO:0061061 196 0.048
Fly
regulation of meiotic cell cycle GO:0051445 1 0.048
meiotic cell cycle process GO:1903046 3 0.046
protein modification process GO:0036211 100 0.046
heart development GO:0007507 313 0.046
head development GO:0060322 303 0.045
protein localization to nucleus GO:0034504 3 0.045
anterior posterior pattern specification GO:0009952 152 0.045
embryonic cranial skeleton morphogenesis GO:0048701 90 0.045
rna biosynthetic process GO:0032774 181 0.044
Fly
regulation of cellular component organization GO:0051128 86 0.044
Fly
macromolecule biosynthetic process GO:0009059 227 0.044
Fly
single organism organelle organization GO:1902589 199 0.043
digestive tract morphogenesis GO:0048546 231 0.043
cellular protein modification process GO:0006464 100 0.043
macromolecular complex subunit organization GO:0043933 74 0.042
oxoacid metabolic process GO:0043436 31 0.042
camera type eye morphogenesis GO:0048593 108 0.042
transcription dna templated GO:0006351 181 0.042
Fly
regulation of macromolecule biosynthetic process GO:0010556 225 0.042
Fly
regulation of biosynthetic process GO:0009889 250 0.041
Fly
positive regulation of cellular metabolic process GO:0031325 94 0.041
regulation of nucleic acid templated transcription GO:1903506 213 0.040
Fly
developmental growth GO:0048589 166 0.040
Fly
sister chromatid cohesion GO:0007062 2 0.039
regulation of cell differentiation GO:0045595 142 0.039
regulation of reproductive process GO:2000241 4 0.038
skeletal system morphogenesis GO:0048705 102 0.038
cell projection organization GO:0030030 284 0.038
embryonic skeletal system development GO:0048706 97 0.037
gastrulation GO:0007369 208 0.036
regulation of cellular biosynthetic process GO:0031326 245 0.036
Fly
immune system process GO:0002376 241 0.036
cell morphogenesis involved in differentiation GO:0000904 195 0.036
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.036
Fly
positive regulation of transport GO:0051050 2 0.036
mesenchyme development GO:0060485 127 0.036
somitogenesis GO:0001756 87 0.035
carboxylic acid metabolic process GO:0019752 22 0.035
response to organic substance GO:0010033 153 0.034
sexual reproduction GO:0019953 36 0.034
specification of symmetry GO:0009799 204 0.033
cytoskeleton organization GO:0007010 96 0.033
immune system development GO:0002520 191 0.033
central nervous system development GO:0007417 387 0.033
Fly
mitochondrion organization GO:0007005 4 0.033
Mouse
cell aging GO:0007569 2 0.032
determination of intestine left right asymmetry GO:0071908 2 0.032
lateral line system development GO:0048925 76 0.032
aging GO:0007568 2 0.032
regulation of protein localization to nucleus GO:1900180 2 0.031
cell projection morphogenesis GO:0048858 244 0.031
determination of left right symmetry GO:0007368 179 0.031
system process GO:0003008 185 0.031
neuron projection morphogenesis GO:0048812 161 0.030
neuron projection development GO:0031175 180 0.030
organic acid metabolic process GO:0006082 31 0.030
positive regulation of cellular component biogenesis GO:0044089 3 0.030
endoderm development GO:0007492 49 0.030
homeostatic process GO:0042592 142 0.030
eye photoreceptor cell differentiation GO:0001754 45 0.029
response to external stimulus GO:0009605 264 0.029
response to drug GO:0042493 3 0.029
negative regulation of metabolic process GO:0009892 86 0.029
organelle organization GO:0006996 227 0.028
Mouse
negative regulation of macromolecule metabolic process GO:0010605 76 0.028
regulation of cell activation GO:0050865 1 0.027
behavior GO:0007610 74 0.027
mitotic g2 dna damage checkpoint GO:0007095 3 0.027
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.027
Fly
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.027
regulation of protein import into nucleus GO:0042306 2 0.027
heterocycle biosynthetic process GO:0018130 215 0.027
Fly
negative regulation of reproductive process GO:2000242 3 0.026
cell cycle process GO:0022402 53 0.026
g2 dna damage checkpoint GO:0031572 3 0.026
cellular localization GO:0051641 97 0.026
nuclear transport GO:0051169 4 0.026
positive regulation of catabolic process GO:0009896 4 0.026
vasculature development GO:0001944 278 0.026
sensory system development GO:0048880 76 0.026
central nervous system neuron development GO:0021954 29 0.025
regulation of signaling GO:0023051 235 0.025
Fly
hematopoietic or lymphoid organ development GO:0048534 191 0.025
centrosome organization GO:0051297 1 0.025
adult behavior GO:0030534 2 0.025
regulation of rna biosynthetic process GO:2001141 213 0.025
Fly
growth GO:0040007 174 0.025
Fly
cellular protein metabolic process GO:0044267 129 0.025
regulation of circadian rhythm GO:0042752 4 0.025
septum transversum development GO:0003343 4 0.024
regulation of cellular ketone metabolic process GO:0010565 7 0.024
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.024
apoptotic process GO:0006915 116 0.024
meiosis i GO:0007127 1 0.024
peptidyl serine phosphorylation GO:0018105 1 0.024
cell matrix adhesion GO:0007160 4 0.023
proepicardium development GO:0003342 4 0.023
regulation of establishment of protein localization GO:0070201 4 0.023
erythrocyte differentiation GO:0030218 54 0.023
regulation of gene expression GO:0010468 265 0.022
Fly
amine metabolic process GO:0009308 2 0.022
transport GO:0006810 220 0.022
cell death GO:0008219 121 0.022
positive regulation of exocytosis GO:0045921 1 0.022
female gonad development GO:0008585 4 0.022
cellular amine metabolic process GO:0044106 2 0.021
reproductive process GO:0022414 40 0.021
regulation of binding GO:0051098 3 0.021
embryonic skeletal system morphogenesis GO:0048704 93 0.021
positive regulation of cellular catabolic process GO:0031331 3 0.021
nuclear import GO:0051170 3 0.021
localization of cell GO:0051674 244 0.021
maintenance of location GO:0051235 4 0.021
positive regulation of nucleic acid templated transcription GO:1903508 57 0.021
epithelial cell differentiation GO:0030855 116 0.021
chromosome segregation GO:0007059 12 0.021
regulation of cell matrix adhesion GO:0001952 1 0.021
cellular protein catabolic process GO:0044257 4 0.021
polarized epithelial cell differentiation GO:0030859 4 0.021
stem cell development GO:0048864 82 0.021
cellular response to oxygen levels GO:0071453 1 0.020
microtubule organizing center organization GO:0031023 1 0.020
enzyme linked receptor protein signaling pathway GO:0007167 106 0.020
positive regulation of rna metabolic process GO:0051254 59 0.020
convergent extension GO:0060026 118 0.020
pole plasm assembly GO:0007315 4 0.020
proteasomal protein catabolic process GO:0010498 2 0.020
regulation of cellular amino acid metabolic process GO:0006521 0 0.020
regulation of cell shape GO:0008360 1 0.020
small molecule metabolic process GO:0044281 77 0.020
central nervous system neuron differentiation GO:0021953 74 0.020
determination of left right asymmetry in lateral mesoderm GO:0003140 20 0.020
establishment of localization in cell GO:0051649 77 0.020
organonitrogen compound metabolic process GO:1901564 74 0.020
regulation of intracellular protein transport GO:0033157 3 0.019
regulation of cellular amine metabolic process GO:0033238 0 0.019
development of primary female sexual characteristics GO:0046545 4 0.019
organelle assembly GO:0070925 110 0.019
myeloid cell differentiation GO:0030099 86 0.019
somite development GO:0061053 96 0.019
double strand break repair GO:0006302 3 0.019
cellular component biogenesis GO:0044085 178 0.019
Fly
cell motility GO:0048870 244 0.019
embryonic viscerocranium morphogenesis GO:0048703 52 0.018
death GO:0016265 121 0.018
negative regulation of cellular metabolic process GO:0031324 77 0.018
regulation of localization GO:0032879 104 0.018
angiogenesis GO:0001525 158 0.018
homeostasis of number of cells GO:0048872 62 0.018
axon development GO:0061564 166 0.018
convergent extension involved in gastrulation GO:0060027 71 0.018
protein dephosphorylation GO:0006470 3 0.018
single organism transport GO:0044765 206 0.018
establishment of localization GO:0051234 244 0.018
mesoderm morphogenesis GO:0048332 51 0.018
positive regulation of macromolecule metabolic process GO:0010604 93 0.018
actomyosin structure organization GO:0031032 53 0.018
peptidyl lysine acetylation GO:0018394 2 0.018
segmentation GO:0035282 97 0.018
regulation of developmental growth GO:0048638 38 0.018
Fly
forebrain cell migration GO:0021885 1 0.018
epithelial tube morphogenesis GO:0060562 148 0.018
macromolecule modification GO:0043412 111 0.018
axial mesoderm morphogenesis GO:0048319 8 0.017
transcription from rna polymerase ii promoter GO:0006366 80 0.017
Fly
cell migration involved in gastrulation GO:0042074 79 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.017
regulation of synapse organization GO:0050807 3 0.017
Fly
lipid storage GO:0019915 1 0.017
reproduction GO:0000003 40 0.017
establishment of apical basal cell polarity GO:0035089 2 0.017
heart morphogenesis GO:0003007 156 0.017
recombinational repair GO:0000725 1 0.017
regulation of protein targeting GO:1903533 2 0.017
mitotic dna integrity checkpoint GO:0044774 4 0.017
atp catabolic process GO:0006200 4 0.017
chromatin modification GO:0016568 21 0.017
fertilization GO:0009566 3 0.017
intracellular signal transduction GO:0035556 85 0.017
regulation of cell substrate adhesion GO:0010810 1 0.017
protein acylation GO:0043543 3 0.016
nerve development GO:0021675 45 0.016
connective tissue development GO:0061448 99 0.016
neural tube development GO:0021915 62 0.016
hemopoiesis GO:0030097 183 0.016
lateral inhibition GO:0046331 1 0.016
cartilage condensation GO:0001502 3 0.016
protein targeting to nucleus GO:0044744 3 0.016
skeletal muscle organ development GO:0060538 78 0.016
response to hexose GO:0009746 3 0.016
regulation of response to stimulus GO:0048583 269 0.016
Fly
protein import into nucleus GO:0006606 3 0.016
regulation of protein catabolic process GO:0042176 1 0.016
positive regulation of biosynthetic process GO:0009891 68 0.016
positive regulation of cell adhesion GO:0045785 1 0.016
female sex differentiation GO:0046660 4 0.015
pectoral fin development GO:0033339 50 0.015
rna 3 end processing GO:0031123 2 0.015
axonogenesis GO:0007409 152 0.015
rna stabilization GO:0043489 4 0.015
single organism nuclear import GO:1902593 3 0.015
negative regulation of nucleic acid templated transcription GO:1903507 45 0.015
energy reserve metabolic process GO:0006112 2 0.015
cellular component assembly GO:0022607 170 0.015
Fly
regulation of signal transduction GO:0009966 225 0.015
Fly
response to monosaccharide GO:0034284 3 0.014
peptidyl serine modification GO:0018209 2 0.014
cell aggregation GO:0098743 3 0.014
ribonucleoside monophosphate catabolic process GO:0009158 4 0.014
positive regulation of gene expression GO:0010628 71 0.014
lateral line development GO:0048882 66 0.014
maternal determination of anterior posterior axis embryo GO:0008358 4 0.014
positive regulation of secretion GO:0051047 1 0.014
regulation of gene expression epigenetic GO:0040029 11 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.014
Fly
membrane invagination GO:0010324 1 0.014
stem cell differentiation GO:0048863 117 0.014
positive regulation of multicellular organismal process GO:0051240 52 0.014
positive regulation of immune effector process GO:0002699 3 0.014
long chain fatty acid metabolic process GO:0001676 1 0.014
negative regulation of response to stimulus GO:0048585 104 0.014
determination of bilateral symmetry GO:0009855 204 0.014
centrosome cycle GO:0007098 1 0.014
positive regulation of cell cycle GO:0045787 3 0.013
ear development GO:0043583 127 0.013
regulation of cell morphogenesis GO:0022604 42 0.013
cell substrate adhesion GO:0031589 4 0.013
cognition GO:0050890 1 0.013
regulation of cytoplasmic transport GO:1903649 4 0.013
tissue homeostasis GO:0001894 25 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.013
exocytosis GO:0006887 1 0.013
developmental growth involved in morphogenesis GO:0060560 86 0.013
nucleoside monophosphate catabolic process GO:0009125 4 0.013
myofibril assembly GO:0030239 48 0.013
mitotic sister chromatid cohesion GO:0007064 2 0.013
double strand break repair via homologous recombination GO:0000724 1 0.013
negative regulation of developmental process GO:0051093 65 0.013
Fly
negative regulation of biosynthetic process GO:0009890 55 0.013
positive regulation of apoptotic signaling pathway GO:2001235 1 0.013
establishment of protein localization to organelle GO:0072594 4 0.013
positive regulation of nucleoside metabolic process GO:0045979 1 0.013
regulation of protein transport GO:0051223 3 0.013
axon guidance GO:0007411 86 0.013
lipid homeostasis GO:0055088 3 0.013
leukocyte differentiation GO:0002521 25 0.013
regulation of production of molecular mediator of immune response GO:0002700 1 0.013
regulation of anatomical structure morphogenesis GO:0022603 130 0.013
synaptic target recognition GO:0008039 1 0.013
phagocytosis engulfment GO:0006911 1 0.012
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.012
internal protein amino acid acetylation GO:0006475 2 0.012
astrocyte differentiation GO:0048708 1 0.012
protein acetylation GO:0006473 2 0.012
regeneration GO:0031099 91 0.012
rna localization GO:0006403 4 0.012
protein complex subunit organization GO:0071822 46 0.012
inner ear development GO:0048839 126 0.012
negative regulation of cell communication GO:0010648 96 0.012
homeostasis of number of cells within a tissue GO:0048873 4 0.012
striated muscle tissue development GO:0014706 110 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.012
single fertilization GO:0007338 3 0.012
meiotic chromosome segregation GO:0045132 3 0.012
cell cycle arrest GO:0007050 1 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.012
purine nucleoside monophosphate catabolic process GO:0009128 4 0.012
nuclear division GO:0000280 23 0.012
pronephros development GO:0048793 69 0.012
neuronal stem cell maintenance GO:0097150 2 0.012
cellular component assembly involved in morphogenesis GO:0010927 107 0.012
compound eye development GO:0048749 2 0.011
positive regulation of dna metabolic process GO:0051054 1 0.011
blood vessel morphogenesis GO:0048514 216 0.011
regulation of photoreceptor cell differentiation GO:0046532 2 0.011
tissue regeneration GO:0042246 74 0.011
methylation GO:0032259 22 0.011
regulation of reactive oxygen species metabolic process GO:2000377 2 0.011
modification dependent macromolecule catabolic process GO:0043632 3 0.011
negative regulation of cell differentiation GO:0045596 46 0.011
regulation of synapse assembly GO:0051963 3 0.011
Fly
erythrocyte homeostasis GO:0034101 55 0.011
production of molecular mediator of immune response GO:0002440 2 0.011
gene silencing GO:0016458 4 0.011
establishment of epithelial cell polarity GO:0090162 2 0.011
heart looping GO:0001947 94 0.011
olfactory lobe development GO:0021988 4 0.011
mrna 3 end processing GO:0031124 2 0.011
photoreceptor cell differentiation GO:0046530 55 0.011
cellular response to external stimulus GO:0071496 2 0.011
multicellular organismal reproductive process GO:0048609 35 0.011
regulation of catalytic activity GO:0050790 55 0.011
regulation of cytokine production GO:0001817 3 0.011
negative regulation of multicellular organismal process GO:0051241 69 0.011
Fly
b cell activation GO:0042113 2 0.011
regulation of cell communication GO:0010646 232 0.011
Fly
regulation of phosphate metabolic process GO:0019220 43 0.011
neurological system process GO:0050877 62 0.011
regulation of myotube differentiation GO:0010830 2 0.011
cellular response to light stimulus GO:0071482 4 0.011
limb bud formation GO:0060174 2 0.011
negative regulation of multi organism process GO:0043901 3 0.011
regulation of protein ubiquitination GO:0031396 3 0.011
hormone transport GO:0009914 2 0.011
negative regulation of signaling GO:0023057 96 0.011
cell death in response to oxidative stress GO:0036473 2 0.011
lens development in camera type eye GO:0002088 22 0.011
regulation of jak stat cascade GO:0046425 3 0.011
extrinsic apoptotic signaling pathway GO:0097191 3 0.011
single organism biosynthetic process GO:0044711 71 0.011
cellular amino acid metabolic process GO:0006520 7 0.010
internal peptidyl lysine acetylation GO:0018393 2 0.010
cell fate commitment GO:0045165 99 0.010
embryonic eye morphogenesis GO:0048048 30 0.010
eye photoreceptor cell development GO:0042462 30 0.010
mitochondrial transport GO:0006839 2 0.010
histone h3 k4 methylation GO:0051568 2 0.010
glial cell proliferation GO:0014009 4 0.010
gamete generation GO:0007276 33 0.010
response to alkaloid GO:0043279 2 0.010
regulation of apoptotic process GO:0042981 98 0.010
negative regulation of cell migration GO:0030336 17 0.010
regulation of cell migration GO:0030334 40 0.010
peripheral nervous system development GO:0007422 55 0.010
immunoglobulin mediated immune response GO:0016064 3 0.010
cartilage development GO:0051216 96 0.010
positive regulation of stem cell proliferation GO:2000648 1 0.010
negative regulation of rna biosynthetic process GO:1902679 45 0.010
striated muscle cell development GO:0055002 108 0.010
developmental maturation GO:0021700 34 0.010

nrf1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org