Danio rerio

11 known processes

insrb

insulin receptor b

(Aliases: IRb,si:dkey-6n3.1)

insrb biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
generation of neurons GO:0048699 385 0.742
Zebrafish Fly
regulation of circadian sleep wake cycle GO:0042749 1 0.683
Fly
heart development GO:0007507 313 0.682
Human Zebrafish
larval development GO:0002164 2 0.623
Worm
circadian sleep wake cycle process GO:0022410 2 0.599
Fly
heart morphogenesis GO:0003007 156 0.584
Human Zebrafish
signal transduction GO:0007165 455 0.579
Human Zebrafish Mouse Rat Fly
regulation of primary metabolic process GO:0080090 311 0.554
Human Zebrafish Mouse Rat
neuron differentiation GO:0030182 353 0.544
Zebrafish Fly
circadian sleep wake cycle GO:0042745 2 0.521
Fly
sleep GO:0030431 1 0.520
Fly
cellular component morphogenesis GO:0032989 336 0.519
Fly
tube morphogenesis GO:0035239 349 0.478
Zebrafish
aging GO:0007568 2 0.463
Worm Fly
head development GO:0060322 303 0.442
regulation of glucose transport GO:0010827 1 0.430
Human
embryonic organ development GO:0048568 381 0.415
Zebrafish
brain development GO:0007420 293 0.411
multi organism cellular process GO:0044764 2 0.409
Human
regulation of cell communication GO:0010646 232 0.404
Human Worm
circadian sleep wake cycle sleep GO:0050802 1 0.393
Fly
regulation of circadian sleep wake cycle sleep GO:0045187 1 0.379
Fly
digestive system development GO:0055123 289 0.378
Mouse
female sex differentiation GO:0046660 4 0.372
Fly
negative regulation of ras protein signal transduction GO:0046580 1 0.365
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.364
cell surface receptor signaling pathway GO:0007166 325 0.352
Human Zebrafish Mouse Rat Fly
glucose import GO:0046323 2 0.339
Human
regulation of signaling GO:0023051 235 0.326
Human
response to external stimulus GO:0009605 264 0.313
Rat Worm Fly
central nervous system development GO:0007417 387 0.305
Zebrafish
response to nutrient GO:0007584 3 0.304
Rat
cellular macromolecule metabolic process GO:0044260 391 0.304
Human Zebrafish Mouse Rat Fly
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.302
Fly
nitric oxide metabolic process GO:0046209 2 0.302
Human
cellular response to external stimulus GO:0071496 2 0.293
Worm
cell projection organization GO:0030030 284 0.276
Fly
axon development GO:0061564 166 0.267
Fly
negative regulation of cellular process GO:0048523 283 0.265
Zebrafish Rat Worm Fly
cellular nitrogen compound biosynthetic process GO:0044271 218 0.260
Human
energy reserve metabolic process GO:0006112 2 0.259
Human Mouse
morphogenesis of an epithelium GO:0002009 333 0.259
cell motility GO:0048870 244 0.252
Human Zebrafish
digestive tract morphogenesis GO:0048546 231 0.251
regulation of signal transduction GO:0009966 225 0.250
Human
neuron development GO:0048666 262 0.242
Fly
viral process GO:0016032 1 0.241
Human
neuron projection development GO:0031175 180 0.230
Fly
regulation of establishment of protein localization GO:0070201 4 0.227
Worm
cell morphogenesis involved in differentiation GO:0000904 195 0.218
Fly
response to chemical GO:0042221 320 0.214
Human Mouse Rat Worm Fly
locomotion GO:0040011 313 0.212
Human Zebrafish Worm Fly
negative regulation of autophagy GO:0010507 1 0.212
Fly
determination of heart left right asymmetry GO:0061371 117 0.210
cellular component movement GO:0006928 335 0.210
Human Zebrafish Fly
regulation of biological quality GO:0065008 263 0.207
Human Rat Worm Fly
positive regulation of protein kinase b signaling GO:0051897 1 0.207
Human
organelle organization GO:0006996 227 0.205
Human Mouse Worm
cellular carbohydrate metabolic process GO:0044262 4 0.203
Human Mouse
organelle assembly GO:0070925 110 0.203
Worm
circadian rhythm GO:0007623 19 0.202
Fly
camera type eye development GO:0043010 222 0.200
Zebrafish
gastrulation GO:0007369 208 0.198
cognition GO:0050890 1 0.198
positive regulation of cellular metabolic process GO:0031325 94 0.197
Human Mouse Rat
modulation by virus of host morphology or physiology GO:0019048 1 0.196
Human
protein heterooligomerization GO:0051291 1 0.196
Human Rat
regulation of multicellular organismal process GO:0051239 277 0.196
Human Worm Fly
cellular component biogenesis GO:0044085 178 0.195
Human Rat Worm
negative regulation of biological process GO:0048519 304 0.192
Zebrafish Rat Worm Fly
neuron remodeling GO:0016322 1 0.189
Fly
determination of bilateral symmetry GO:0009855 204 0.189
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.188
Human
regulation of response to nutrient levels GO:0032107 1 0.186
Worm
regulation of organelle assembly GO:1902115 4 0.185
Worm
lipid storage GO:0019915 1 0.182
Worm
cell morphogenesis GO:0000902 289 0.181
Fly
positive regulation of stress activated mapk cascade GO:0032874 3 0.180
response to decreased oxygen levels GO:0036293 25 0.176
Fly
response to vitamin GO:0033273 3 0.176
Rat
maintenance of location GO:0051235 4 0.176
Worm
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.174
Human
neuron projection guidance GO:0097485 86 0.170
Fly
axon guidance GO:0007411 86 0.169
Fly
regulation of circadian rhythm GO:0042752 4 0.169
Fly
nitric oxide biosynthetic process GO:0006809 2 0.168
Human
response to abiotic stimulus GO:0009628 122 0.159
Worm Fly
reactive nitrogen species metabolic process GO:2001057 0 0.157
regulation of reactive oxygen species metabolic process GO:2000377 2 0.157
Rat Fly
cellular nitrogen compound metabolic process GO:0034641 290 0.155
Human
regulation of multicellular organismal development GO:2000026 223 0.155
Human
embryonic organ morphogenesis GO:0048562 274 0.154
Zebrafish
regulation of cellular metabolic process GO:0031323 320 0.153
Human Zebrafish Mouse Rat Worm Fly
sensory organ morphogenesis GO:0090596 200 0.151
Zebrafish
positive regulation of map kinase activity GO:0043406 3 0.150
Human
cellular macromolecule biosynthetic process GO:0034645 224 0.149
Human Mouse Rat
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.139
Human Mouse Rat
regulation of rna biosynthetic process GO:2001141 213 0.138
Human
germ line stem cell division GO:0042078 1 0.136
Fly
cell part morphogenesis GO:0032990 246 0.134
Fly
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.131
Human Mouse
pericardium development GO:0060039 1 0.130
response to monosaccharide GO:0034284 3 0.129
Rat
eye development GO:0001654 277 0.129
Zebrafish
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 4 0.128
Human
rna metabolic process GO:0016070 219 0.128
Human
nucleobase containing compound biosynthetic process GO:0034654 205 0.127
Human
gene expression GO:0010467 252 0.125
Human Zebrafish Rat
development of primary female sexual characteristics GO:0046545 4 0.125
Fly
cellular component assembly GO:0022607 170 0.124
Human Rat Worm
response to glucocorticoid GO:0051384 1 0.123
Rat
regulation of nitrogen compound metabolic process GO:0051171 251 0.123
Human
response to stress GO:0006950 263 0.121
Zebrafish Worm Fly
wnt signaling pathway GO:0016055 80 0.120
female gonad development GO:0008585 4 0.117
Fly
biological adhesion GO:0022610 40 0.117
ameboidal type cell migration GO:0001667 143 0.117
digestive tract development GO:0048565 265 0.116
negative regulation of cytoplasmic transport GO:1903650 2 0.114
Worm
regulation of transcription dna templated GO:0006355 213 0.114
Human
positive regulation of biological process GO:0048518 253 0.114
Human Mouse Rat Worm Fly
negative regulation of protein phosphorylation GO:0001933 4 0.111
Rat
regulation of response to stimulus GO:0048583 269 0.111
Human Worm Fly
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.111
hindbrain development GO:0030902 91 0.111
regulation of programmed cell death GO:0043067 101 0.110
Zebrafish
regulation of cell death GO:0010941 103 0.110
Zebrafish
specification of symmetry GO:0009799 204 0.109
negative regulation of endopeptidase activity GO:0010951 10 0.108
Zebrafish
multi organism process GO:0051704 134 0.104
Human Zebrafish Worm Fly
response to wounding GO:0009611 116 0.104
Zebrafish
regulation of protein localization to nucleus GO:1900180 2 0.099
Worm
apoptotic process GO:0006915 116 0.099
Zebrafish
regulation of carbohydrate metabolic process GO:0006109 4 0.099
Human Mouse
interspecies interaction between organisms GO:0044419 4 0.098
Human
negative regulation of cellular catabolic process GO:0031330 3 0.098
Fly
blood vessel morphogenesis GO:0048514 216 0.097
embryonic heart tube morphogenesis GO:0003143 108 0.097
negative regulation of protein import into nucleus GO:0042308 2 0.096
Worm
regulation of cytokine production GO:0001817 3 0.094
positive regulation of cellular process GO:0048522 201 0.094
Human Mouse Rat Fly
regulation of cellular biosynthetic process GO:0031326 245 0.094
Human Mouse Rat
immune system process GO:0002376 241 0.093
positive regulation of signal transduction GO:0009967 56 0.092
Human
embryo development ending in birth or egg hatching GO:0009792 271 0.092
Fly
regulation of biosynthetic process GO:0009889 250 0.089
Human Mouse Rat
transmission of nerve impulse GO:0019226 19 0.089
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.089
Human
heterocycle metabolic process GO:0046483 290 0.088
Human
negative regulation of catabolic process GO:0009895 3 0.086
Fly
establishment of protein localization to organelle GO:0072594 4 0.086
Worm
retina development in camera type eye GO:0060041 146 0.086
positive regulation of metabolic process GO:0009893 108 0.085
Human Mouse Rat
astrocyte differentiation GO:0048708 1 0.084
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.083
Zebrafish Fly
protein import GO:0017038 3 0.083
Worm
regulation of macromolecule metabolic process GO:0060255 317 0.083
Human Zebrafish Mouse Rat
cell migration involved in gastrulation GO:0042074 79 0.083
blood vessel development GO:0001568 246 0.081
heterocycle biosynthetic process GO:0018130 215 0.081
Human
negative regulation of response to cytokine stimulus GO:0060761 2 0.080
embryonic heart tube development GO:0035050 133 0.079
cell growth GO:0016049 57 0.079
Fly
transcription dna templated GO:0006351 181 0.079
Human
regulation of anatomical structure morphogenesis GO:0022603 130 0.078
positive regulation of glucose transport GO:0010828 1 0.078
Human
organic cyclic compound metabolic process GO:1901360 301 0.077
Human
single organism localization GO:1902578 225 0.076
Human Worm
neuron projection morphogenesis GO:0048812 161 0.076
Fly
cellular response to extracellular stimulus GO:0031668 2 0.075
Worm
positive regulation of jnk cascade GO:0046330 3 0.075
cellular response to hormone stimulus GO:0032870 39 0.075
Human Mouse Rat Fly
positive regulation of cell communication GO:0010647 56 0.075
Human
nucleocytoplasmic transport GO:0006913 4 0.075
Worm
cellular localization GO:0051641 97 0.074
Worm
regulation of developmental process GO:0050793 247 0.074
Human Zebrafish Worm Fly
cell projection morphogenesis GO:0048858 244 0.073
Fly
negative regulation of cell communication GO:0010648 96 0.072
medulla oblongata development GO:0021550 4 0.072
oxidation reduction process GO:0055114 41 0.072
Human Mouse
nuclear import GO:0051170 3 0.072
Worm
insulin like growth factor receptor signaling pathway GO:0048009 4 0.072
Zebrafish
response to glucose GO:0009749 3 0.072
Rat
chemotaxis GO:0006935 104 0.072
Fly
pyruvate metabolic process GO:0006090 1 0.071
Human
positive regulation of macromolecule metabolic process GO:0010604 93 0.071
Human Mouse Rat
muscle tissue development GO:0060537 110 0.071
nucleobase containing compound metabolic process GO:0006139 274 0.070
Human
localization of cell GO:0051674 244 0.070
Human Zebrafish
organic cyclic compound biosynthetic process GO:1901362 223 0.070
Human
regulation of immune system process GO:0002682 34 0.070
hydrogen peroxide metabolic process GO:0042743 2 0.069
Rat
nucleic acid metabolic process GO:0090304 244 0.069
Human
organonitrogen compound metabolic process GO:1901564 74 0.069
aromatic compound biosynthetic process GO:0019438 217 0.069
Human
positive regulation of transport GO:0051050 2 0.069
Human
negative regulation of response to stimulus GO:0048585 104 0.069
Fly
regulation of protein transport GO:0051223 3 0.069
Worm
taxis GO:0042330 109 0.068
Fly
cellular component assembly involved in morphogenesis GO:0010927 107 0.068
nitrogen compound metabolic process GO:0006807 319 0.068
Human
centrosome organization GO:0051297 1 0.068
gastrulation with mouth forming second GO:0001702 44 0.068
regulation of tube size GO:0035150 2 0.067
cellular response to chemical stimulus GO:0070887 157 0.067
Human Mouse Rat Fly
negative regulation of intracellular transport GO:0032387 3 0.067
Worm
cellular biosynthetic process GO:0044249 286 0.067
Human Mouse Rat
negative regulation of multicellular organismal process GO:0051241 69 0.066
Fly
macroautophagy GO:0016236 1 0.066
Worm
single organismal cell cell adhesion GO:0016337 29 0.066
multicellular organism reproduction GO:0032504 35 0.065
Zebrafish Worm Fly
glucose homeostasis GO:0042593 1 0.065
Human Rat
regulation of multicellular organism growth GO:0040014 4 0.065
Worm Fly
hemopoiesis GO:0030097 183 0.064
biosynthetic process GO:0009058 294 0.064
Human Mouse Rat
regulation of protein catabolic process GO:0042176 1 0.064
cellular aromatic compound metabolic process GO:0006725 295 0.063
Human
reactive oxygen species biosynthetic process GO:1903409 1 0.063
cell proliferation GO:0008283 80 0.063
Human Fly
cell differentiation in spinal cord GO:0021515 40 0.061
Zebrafish
determination of left right symmetry GO:0007368 179 0.061
post embryonic organ development GO:0048569 4 0.061
muscle structure development GO:0061061 196 0.061
Fly
gland development GO:0048732 143 0.061
regulation of organ growth GO:0046620 3 0.060
Fly
negative regulation of signaling GO:0023057 96 0.060
liver development GO:0001889 96 0.059
intracellular signal transduction GO:0035556 85 0.059
Human
synaptic target recognition GO:0008039 1 0.059
neuronal action potential GO:0019228 18 0.059
photoreceptor cell outer segment organization GO:0035845 9 0.058
ear development GO:0043583 127 0.058
Zebrafish
hepaticobiliary system development GO:0061008 98 0.058
response to alkaloid GO:0043279 2 0.057
Fly
single organism cell adhesion GO:0098602 29 0.057
cellular response to nutrient levels GO:0031669 2 0.057
Worm
somatic muscle development GO:0007525 4 0.057
Fly
angiogenesis GO:0001525 158 0.056
g protein coupled receptor signaling pathway GO:0007186 74 0.056
Human
aorta development GO:0035904 4 0.056
single organism transport GO:0044765 206 0.056
Human Worm
convergent extension GO:0060026 118 0.056
reproduction GO:0000003 40 0.055
Zebrafish Worm Fly
regulation of dna replication GO:0006275 3 0.055
Human
response to carbohydrate GO:0009743 3 0.055
Rat
regulation of response to oxidative stress GO:1902882 2 0.055
Worm
mesoderm development GO:0007498 88 0.054
response to ketone GO:1901654 1 0.054
Rat
chemical homeostasis GO:0048878 49 0.054
Human Rat
programmed cell death GO:0012501 119 0.054
Zebrafish
regulation of gene expression GO:0010468 265 0.054
Human Zebrafish Rat
sexual reproduction GO:0019953 36 0.054
Zebrafish Worm Fly
syncytium formation GO:0006949 12 0.054
Fly
positive regulation of cell proliferation GO:0008284 15 0.052
Human Fly
tissue regeneration GO:0042246 74 0.052
Zebrafish
pancreas development GO:0031016 84 0.052
Mouse
behavior GO:0007610 74 0.052
Fly
regulation of metabolic process GO:0019222 359 0.052
Human Zebrafish Mouse Rat Worm Fly
establishment or maintenance of polarity of embryonic epithelium GO:0016332 2 0.051
adherens junction organization GO:0034332 4 0.050
organic substance biosynthetic process GO:1901576 289 0.050
Human Mouse Rat
regulation of cellular component organization GO:0051128 86 0.050
Human Mouse Worm Fly
cell migration GO:0016477 237 0.049
Human Zebrafish
multicellular organismal signaling GO:0035637 22 0.049
negative regulation of protein localization to nucleus GO:1900181 2 0.049
Worm
nuclear transport GO:0051169 4 0.048
Worm
response to other organism GO:0051707 97 0.048
regulation of anatomical structure size GO:0090066 33 0.048
Fly
epithelial tube morphogenesis GO:0060562 148 0.048
single organism nuclear import GO:1902593 3 0.047
Worm
formation of primary germ layer GO:0001704 62 0.047
ventral spinal cord development GO:0021517 35 0.047
Zebrafish
regulation of macromolecule biosynthetic process GO:0010556 225 0.047
Human Mouse Rat
regulation of response to stress GO:0080134 36 0.046
Worm
nucleic acid templated transcription GO:0097659 181 0.046
Human
regulation of blood vessel size GO:0050880 2 0.046
positive regulation of cellular biosynthetic process GO:0031328 68 0.046
Human Mouse Rat
wound healing GO:0042060 90 0.045
Zebrafish
rna biosynthetic process GO:0032774 181 0.045
Human
muscle organ development GO:0007517 101 0.045
interaction with host GO:0051701 4 0.045
Human
response to light stimulus GO:0009416 46 0.045
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.045
Zebrafish
stem cell division GO:0017145 1 0.044
Fly
type i interferon production GO:0032606 2 0.044
establishment of localization GO:0051234 244 0.044
Human Rat Worm
single organism behavior GO:0044708 24 0.043
Fly
multi organism reproductive process GO:0044703 36 0.043
Zebrafish Worm Fly
multicellular organism growth GO:0035264 4 0.043
Worm Fly
system process GO:0003008 185 0.043
carbohydrate homeostasis GO:0033500 1 0.043
Human Rat
extrinsic apoptotic signaling pathway GO:0097191 3 0.042
response to hexose GO:0009746 3 0.042
Rat
response to hypoxia GO:0001666 25 0.042
protein localization to nucleus GO:0034504 3 0.042
Worm
single organism biosynthetic process GO:0044711 71 0.042
Human Mouse
hormone transport GO:0009914 2 0.042
phosphate containing compound metabolic process GO:0006796 108 0.041
Human Mouse Rat Fly
stem cell maintenance GO:0019827 4 0.041
negative regulation of cytokine mediated signaling pathway GO:0001960 2 0.041
sensory organ development GO:0007423 393 0.041
Zebrafish
regulation of metal ion transport GO:0010959 4 0.040
sex determination GO:0007530 1 0.040
Mouse
transport GO:0006810 220 0.040
Human Rat Worm
mitotic cell cycle GO:0000278 64 0.039
Human Mouse
regulation of cell shape GO:0008360 1 0.039
signal transduction in absence of ligand GO:0038034 1 0.039
inner ear development GO:0048839 126 0.038
Zebrafish
protein targeting to nucleus GO:0044744 3 0.038
Worm
negative regulation of signal transduction GO:0009968 94 0.038
single organism organelle organization GO:1902589 199 0.038
Human Mouse
death GO:0016265 121 0.038
Zebrafish
immunoglobulin mediated immune response GO:0016064 3 0.038
hematopoietic or lymphoid organ development GO:0048534 191 0.037
convergent extension involved in gastrulation GO:0060027 71 0.037
negative regulation of intracellular protein transport GO:0090317 3 0.037
Worm
activation of mapk activity GO:0000187 3 0.037
Human
positive regulation of response to stimulus GO:0048584 80 0.037
Human
regulation of nucleocytoplasmic transport GO:0046822 2 0.037
Worm
negative regulation of metabolic process GO:0009892 86 0.037
Zebrafish Rat Fly
developmental growth involved in morphogenesis GO:0060560 86 0.037
positive regulation of signaling GO:0023056 56 0.036
Human
regulation of stem cell differentiation GO:2000736 4 0.036
calcium ion homeostasis GO:0055074 19 0.036
mechanosensory behavior GO:0007638 2 0.036
carbohydrate derivative biosynthetic process GO:1901137 43 0.036
Rat
type b pancreatic cell development GO:0003323 4 0.036
epithelial cell differentiation GO:0030855 116 0.035
negative regulation of cytokine production GO:0001818 1 0.035
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.035
Human
intracellular receptor signaling pathway GO:0030522 30 0.035
blood vessel endothelial cell migration GO:0043534 18 0.035
peptide transport GO:0015833 1 0.035
macromolecule localization GO:0033036 54 0.035
Worm
enzyme linked receptor protein signaling pathway GO:0007167 106 0.034
Human Zebrafish Mouse Rat Fly
growth GO:0040007 174 0.034
regulation of rna metabolic process GO:0051252 224 0.034
Human
cell fate commitment GO:0045165 99 0.034
cellular response to organic substance GO:0071310 105 0.034
Human Mouse Rat Fly
g1 s transition of mitotic cell cycle GO:0000082 1 0.034
vasculature development GO:0001944 278 0.034
cellular response to starvation GO:0009267 1 0.034
Worm
heart looping GO:0001947 94 0.034
regulation of protein metabolic process GO:0051246 56 0.034
Human Zebrafish Rat
positive regulation of nucleic acid templated transcription GO:1903508 57 0.033
exocrine pancreas development GO:0031017 28 0.033
Mouse
response to corticosteroid GO:0031960 1 0.033
Rat
pigment cell differentiation GO:0050931 38 0.033
Zebrafish
cardiac muscle tissue development GO:0048738 48 0.033
protein import into nucleus GO:0006606 3 0.033
Worm
negative regulation of tor signaling GO:0032007 2 0.033
retina morphogenesis in camera type eye GO:0060042 79 0.033
fin regeneration GO:0031101 51 0.033
Zebrafish
negative regulation of protein transport GO:0051224 3 0.033
Worm
regionalization GO:0003002 274 0.033
Zebrafish
regulation of cellular component size GO:0032535 30 0.032
Fly
developmental cell growth GO:0048588 52 0.032
Fly
regulation of intracellular protein transport GO:0033157 3 0.032
Worm
cell cycle g1 s phase transition GO:0044843 1 0.032
cell adhesion GO:0007155 40 0.032
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.032
single organism metabolic process GO:0044710 217 0.032
Human Mouse Worm Fly
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.031
nuclear migration GO:0007097 3 0.030
transcription from rna polymerase ii promoter GO:0006366 80 0.030
protein metabolic process GO:0019538 183 0.030
Human Zebrafish Mouse Rat Fly
cell migration in hindbrain GO:0021535 7 0.030
phosphorus metabolic process GO:0006793 109 0.030
Human Mouse Rat Fly
response to organic substance GO:0010033 153 0.030
Human Mouse Rat Fly
leukocyte proliferation GO:0070661 1 0.030
myeloid leukocyte differentiation GO:0002573 15 0.030
regulation of endopeptidase activity GO:0052548 23 0.030
Zebrafish
positive regulation of glucose import GO:0046326 1 0.029
Human
negative regulation of striated muscle tissue development GO:0045843 2 0.029
positive regulation of rna biosynthetic process GO:1902680 57 0.029
dorsal motor nucleus of vagus nerve development GO:0021744 4 0.029
positive regulation of dna metabolic process GO:0051054 1 0.029
Human
eye morphogenesis GO:0048592 144 0.029
regulation of molecular function GO:0065009 70 0.028
Human Zebrafish Rat
hard palate development GO:0060022 4 0.028
regulation of apoptotic process GO:0042981 98 0.028
Zebrafish
mononuclear cell proliferation GO:0032943 1 0.028
autophagy GO:0006914 4 0.028
Worm Fly
homeostatic process GO:0042592 142 0.027
Human Rat Fly
exocrine system development GO:0035272 28 0.027
Mouse
b cell mediated immunity GO:0019724 3 0.027
somatic cell dna recombination GO:0016444 1 0.027
lymphocyte proliferation GO:0046651 1 0.027
regulation of inflammatory response GO:0050727 2 0.027
endodermal cell fate determination GO:0007493 2 0.027
positive regulation of cell cycle GO:0045787 3 0.027
Human Mouse
positive regulation of transcription dna templated GO:0045893 57 0.027
protein activation cascade GO:0072376 6 0.027
actin filament based process GO:0030029 64 0.027
regulation of phosphorylation GO:0042325 26 0.026
Human Rat
regulation of cysteine type endopeptidase activity GO:2000116 21 0.026
Zebrafish
cell migration involved in heart development GO:0060973 22 0.026
regulation of phosphate metabolic process GO:0019220 43 0.026
Human Rat
muscle cell differentiation GO:0042692 139 0.026
Fly
myeloid cell differentiation GO:0030099 86 0.026
response to oxygen levels GO:0070482 25 0.026
Fly
renal system development GO:0072001 94 0.025
regulation of cell activation GO:0050865 1 0.025
regulation of heart growth GO:0060420 2 0.025
action potential GO:0001508 19 0.025
regulation of type b pancreatic cell development GO:2000074 1 0.025
neuroblast proliferation GO:0007405 2 0.025
sensory perception GO:0007600 39 0.024
germ cell migration GO:0008354 8 0.024
Zebrafish
regulation of protein complex assembly GO:0043254 3 0.024
establishment of protein localization to plasma membrane GO:0090002 1 0.024
developmental growth GO:0048589 166 0.024
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.024
reproductive process GO:0022414 40 0.024
Zebrafish Mouse Worm Fly
muscle cell migration GO:0014812 4 0.024
photoreceptor cell differentiation GO:0046530 55 0.023
modification of morphology or physiology of other organism GO:0035821 4 0.023
Human
regulation of intracellular signal transduction GO:1902531 57 0.023
Human
diencephalon development GO:0021536 58 0.023
positive regulation of cytokine production GO:0001819 2 0.023
regulation of hormone secretion GO:0046883 2 0.023
regulation of protein targeting GO:1903533 2 0.023
Worm
morphogenesis of an epithelial sheet GO:0002011 49 0.023
regeneration GO:0031099 91 0.023
Zebrafish
regulation of nucleic acid templated transcription GO:1903506 213 0.023
Human
macromolecule biosynthetic process GO:0009059 227 0.023
Human Mouse Rat
stem cell development GO:0048864 82 0.023
protein processing GO:0016485 12 0.023
Zebrafish
apical junction assembly GO:0043297 1 0.023
regulation of rho protein signal transduction GO:0035023 2 0.023
axonogenesis GO:0007409 152 0.023
Fly
regulation of cytoplasmic transport GO:1903649 4 0.022
Worm
central nervous system neuron differentiation GO:0021953 74 0.022
Zebrafish
urogenital system development GO:0001655 97 0.022
cellular amine metabolic process GO:0044106 2 0.022
positive regulation of cell adhesion GO:0045785 1 0.022
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.022
regulation of immune response GO:0050776 14 0.022
negative regulation of peptidase activity GO:0010466 10 0.022
Zebrafish
regulation of catalytic activity GO:0050790 55 0.022
Human Zebrafish
negative regulation of macromolecule metabolic process GO:0010605 76 0.022
Zebrafish Rat
rhythmic process GO:0048511 21 0.022
Fly
multicellular organismal reproductive process GO:0048609 35 0.022
Zebrafish Worm Fly
protein modification process GO:0036211 100 0.021
Human Mouse Rat Fly
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.021
negative regulation of hydrolase activity GO:0051346 10 0.021
Zebrafish
developmental pigmentation GO:0048066 48 0.021
Zebrafish
positive regulation of biosynthetic process GO:0009891 68 0.021
Human Mouse Rat
inner ear morphogenesis GO:0042472 63 0.021
Zebrafish
cellular protein modification process GO:0006464 100 0.021
Human Mouse Rat Fly
apoptotic process involved in development GO:1902742 2 0.021
embryonic cranial skeleton morphogenesis GO:0048701 90 0.021
regulation of autophagy GO:0010506 3 0.021
Worm Fly
regulation of response to extracellular stimulus GO:0032104 1 0.021
Worm
circadian behavior GO:0048512 5 0.021
Fly
negative regulation of gene expression GO:0010629 65 0.021
Zebrafish Rat
positive regulation of notch signaling pathway GO:0045747 3 0.021
negative regulation of defense response GO:0031348 2 0.021
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.021
Worm
positive regulation of cellular component biogenesis GO:0044089 3 0.021
positive regulation of neuron apoptotic process GO:0043525 1 0.021
spinal cord motor neuron differentiation GO:0021522 26 0.020
Zebrafish
protein localization GO:0008104 40 0.020
Worm
positive regulation of cell death GO:0010942 29 0.020
small molecule metabolic process GO:0044281 77 0.020
Human
regulation of chondrocyte differentiation GO:0032330 1 0.020
negative chemotaxis GO:0050919 1 0.020
response to radiation GO:0009314 51 0.020
positive regulation of gliogenesis GO:0014015 2 0.020
inositol lipid mediated signaling GO:0048017 2 0.020
spinal cord development GO:0021510 46 0.020
Zebrafish
zymogen activation GO:0031638 3 0.020
oxoacid metabolic process GO:0043436 31 0.020
Human
regulation of protein import into nucleus GO:0042306 2 0.020
Worm
mesenchyme development GO:0060485 127 0.020
microtubule organizing center organization GO:0031023 1 0.020
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.020
Human Mouse Rat
cellular response to stress GO:0033554 62 0.020
Worm Fly
positive regulation of cellular carbohydrate metabolic process GO:0010676 1 0.020
Human Mouse
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.019
phosphatidylinositol mediated signaling GO:0048015 2 0.019
protein kinase b signaling GO:0043491 9 0.019
Human
cell projection assembly GO:0030031 64 0.019
cell aging GO:0007569 2 0.019
cell substrate adhesion GO:0031589 4 0.019

insrb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.213
inherited metabolic disorder DOID:655 0 0.040
Human
disease of metabolism DOID:0014667 0 0.040
Human
muscle tissue disease DOID:66 0 0.027
musculoskeletal system disease DOID:17 0 0.027
myopathy DOID:423 0 0.027
muscular disease DOID:0080000 0 0.027
cardiomyopathy DOID:0050700 0 0.027
intrinsic cardiomyopathy DOID:0060036 0 0.027
cardiovascular system disease DOID:1287 0 0.027
heart disease DOID:114 0 0.027
nervous system disease DOID:863 0 0.025