Danio rerio

11 known processes

insra

insulin receptor a

(Aliases: IRa)

insra biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
circadian sleep wake cycle GO:0042745 2 0.590
Fly
larval development GO:0002164 2 0.492
Worm
sleep GO:0030431 1 0.476
Fly
circadian sleep wake cycle process GO:0022410 2 0.434
Fly
regulation of circadian sleep wake cycle sleep GO:0045187 1 0.351
Fly
regulation of multicellular organismal process GO:0051239 277 0.348
Human Worm Fly
regulation of response to stimulus GO:0048583 269 0.292
Human Worm Fly
cellular nitrogen compound biosynthetic process GO:0044271 218 0.280
Human
aging GO:0007568 2 0.264
Worm Fly
energy reserve metabolic process GO:0006112 2 0.251
Human Mouse
positive regulation of map kinase activity GO:0043406 3 0.240
Human
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.227
vasculature development GO:0001944 278 0.226
regulation of circadian rhythm GO:0042752 4 0.218
Fly
response to stress GO:0006950 263 0.209
Zebrafish Worm Fly
regulation of macromolecule biosynthetic process GO:0010556 225 0.207
Human Mouse Rat
regulation of signaling GO:0023051 235 0.197
Human
localization of cell GO:0051674 244 0.194
Human Zebrafish
cellular component movement GO:0006928 335 0.193
Human Zebrafish Fly
signal transduction GO:0007165 455 0.193
Human Zebrafish Mouse Rat Fly
regulation of circadian sleep wake cycle GO:0042749 1 0.192
Fly
regulation of primary metabolic process GO:0080090 311 0.188
Human Zebrafish Mouse Rat
single organism transport GO:0044765 206 0.187
Human Worm
nucleic acid templated transcription GO:0097659 181 0.178
Human
regulation of biosynthetic process GO:0009889 250 0.175
Human Mouse Rat
cell motility GO:0048870 244 0.173
Human Zebrafish
g protein coupled receptor signaling pathway GO:0007186 74 0.173
Human
neuron differentiation GO:0030182 353 0.170
Zebrafish Fly
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.166
Human Mouse Rat
positive regulation of biological process GO:0048518 253 0.164
Human Mouse Rat Worm Fly
cellular carbohydrate metabolic process GO:0044262 4 0.158
Human Mouse
regulation of cellular metabolic process GO:0031323 320 0.157
Human Zebrafish Mouse Rat Worm Fly
circadian sleep wake cycle sleep GO:0050802 1 0.156
Fly
central nervous system development GO:0007417 387 0.153
Zebrafish
transport GO:0006810 220 0.149
Human Rat Worm
single organism localization GO:1902578 225 0.148
Human Worm
neuron projection development GO:0031175 180 0.145
Fly
response to organic substance GO:0010033 153 0.137
Human Mouse Rat Fly
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.137
Human Mouse
response to carbohydrate GO:0009743 3 0.135
Rat
establishment of protein localization to organelle GO:0072594 4 0.135
Worm
cell surface receptor signaling pathway GO:0007166 325 0.134
Human Zebrafish Mouse Rat Fly
rna biosynthetic process GO:0032774 181 0.134
Human
generation of neurons GO:0048699 385 0.131
Zebrafish Fly
response to external stimulus GO:0009605 264 0.129
Rat Worm Fly
negative regulation of multicellular organismal process GO:0051241 69 0.128
Fly
regulation of metabolic process GO:0019222 359 0.128
Human Zebrafish Mouse Rat Worm Fly
regulation of multicellular organism growth GO:0040014 4 0.128
Worm Fly
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.127
Human
negative regulation of biological process GO:0048519 304 0.125
Zebrafish Rat Worm Fly
biosynthetic process GO:0009058 294 0.125
Human Mouse Rat
protein import into nucleus GO:0006606 3 0.122
Worm
lipid storage GO:0019915 1 0.122
Worm
response to glucose GO:0009749 3 0.121
Rat
regulation of multicellular organismal development GO:2000026 223 0.120
Human
regulation of protein transport GO:0051223 3 0.119
Worm
locomotion GO:0040011 313 0.118
Human Zebrafish Worm Fly
negative regulation of cellular process GO:0048523 283 0.118
Zebrafish Rat Worm Fly
organic cyclic compound biosynthetic process GO:1901362 223 0.118
Human
establishment of localization GO:0051234 244 0.117
Human Rat Worm
reactive nitrogen species metabolic process GO:2001057 0 0.113
blood vessel development GO:0001568 246 0.110
nucleocytoplasmic transport GO:0006913 4 0.109
Worm
regulation of gene expression GO:0010468 265 0.107
Human Zebrafish Rat
negative regulation of ras protein signal transduction GO:0046580 1 0.106
regulation of nitrogen compound metabolic process GO:0051171 251 0.105
Human
regulation of biological quality GO:0065008 263 0.105
Human Rat Worm Fly
behavior GO:0007610 74 0.105
Fly
cellular response to organic substance GO:0071310 105 0.103
Human Mouse Rat Fly
rna metabolic process GO:0016070 219 0.103
Human
regulation of organ growth GO:0046620 3 0.103
Fly
response to oxygen containing compound GO:1901700 55 0.102
Human Mouse Rat Worm Fly
organic cyclic compound metabolic process GO:1901360 301 0.101
Human
stem cell division GO:0017145 1 0.101
Fly
blood vessel morphogenesis GO:0048514 216 0.101
cellular macromolecule metabolic process GO:0044260 391 0.099
Human Zebrafish Mouse Rat Fly
regulation of cell growth GO:0001558 29 0.099
Fly
regulation of rna biosynthetic process GO:2001141 213 0.099
Human
negative regulation of cytoplasmic transport GO:1903650 2 0.097
Worm
regulation of cytokine production GO:0001817 3 0.096
regulation of localization GO:0032879 104 0.094
Human Rat Worm
regulation of macromolecule metabolic process GO:0060255 317 0.093
Human Zebrafish Mouse Rat
cellular biosynthetic process GO:0044249 286 0.091
Human Mouse Rat
maintenance of location GO:0051235 4 0.091
Worm
cellular response to external stimulus GO:0071496 2 0.090
Worm
single organism metabolic process GO:0044710 217 0.089
Human Mouse Worm Fly
immune system process GO:0002376 241 0.088
axonogenesis GO:0007409 152 0.088
Fly
neuron projection morphogenesis GO:0048812 161 0.085
Fly
positive regulation of transport GO:0051050 2 0.083
Human
cellular macromolecule biosynthetic process GO:0034645 224 0.082
Human Mouse Rat
organic substance transport GO:0071702 58 0.080
Human Worm
nuclear transport GO:0051169 4 0.079
Worm
response to hexose GO:0009746 3 0.079
Rat
regulation of transcription dna templated GO:0006355 213 0.077
Human
gene expression GO:0010467 252 0.077
Human Zebrafish Rat
regulation of establishment of protein localization GO:0070201 4 0.077
Worm
multicellular organism growth GO:0035264 4 0.075
Worm Fly
response to wounding GO:0009611 116 0.075
Zebrafish
intracellular signal transduction GO:0035556 85 0.074
Human
regulation of nucleic acid templated transcription GO:1903506 213 0.074
Human
macromolecule biosynthetic process GO:0009059 227 0.074
Human Mouse Rat
aromatic compound biosynthetic process GO:0019438 217 0.074
Human
regulation of developmental process GO:0050793 247 0.073
Human Zebrafish Worm Fly
regulation of carbohydrate metabolic process GO:0006109 4 0.072
Human Mouse
negative regulation of gene expression GO:0010629 65 0.071
Zebrafish Rat
cellular component morphogenesis GO:0032989 336 0.071
Fly
positive regulation of glucose transport GO:0010828 1 0.070
Human
response to abiotic stimulus GO:0009628 122 0.070
Worm Fly
organic substance biosynthetic process GO:1901576 289 0.070
Human Mouse Rat
chemotaxis GO:0006935 104 0.069
Fly
female sex differentiation GO:0046660 4 0.069
Fly
regulation of cell communication GO:0010646 232 0.069
Human Worm
response to alkaloid GO:0043279 2 0.068
Fly
negative regulation of protein transport GO:0051224 3 0.068
Worm
cell migration GO:0016477 237 0.068
Human Zebrafish
head development GO:0060322 303 0.066
heart morphogenesis GO:0003007 156 0.066
Human Zebrafish
cellular response to extracellular stimulus GO:0031668 2 0.066
Worm
small molecule metabolic process GO:0044281 77 0.065
Human
embryo development ending in birth or egg hatching GO:0009792 271 0.065
Fly
oxidation reduction process GO:0055114 41 0.064
Human Mouse
single organism nuclear import GO:1902593 3 0.064
Worm
response to chemical GO:0042221 320 0.062
Human Mouse Rat Worm Fly
positive regulation of cellular process GO:0048522 201 0.061
Human Mouse Rat Fly
eye development GO:0001654 277 0.061
Zebrafish
regulation of neuron differentiation GO:0045664 56 0.060
regulation of signal transduction GO:0009966 225 0.060
Human
development of primary female sexual characteristics GO:0046545 4 0.060
Fly
rhythmic process GO:0048511 21 0.060
Fly
positive regulation of response to stimulus GO:0048584 80 0.060
Human
negative regulation of response to stimulus GO:0048585 104 0.059
Fly
somatic muscle development GO:0007525 4 0.059
Fly
neuron development GO:0048666 262 0.059
Fly
response to monosaccharide GO:0034284 3 0.058
Rat
protein targeting to nucleus GO:0044744 3 0.058
Worm
cellular response to starvation GO:0009267 1 0.058
Worm
glucose import GO:0046323 2 0.057
Human
positive regulation of protein kinase b signaling GO:0051897 1 0.057
Human
positive regulation of multicellular organismal process GO:0051240 52 0.057
Worm Fly
regulation of rna metabolic process GO:0051252 224 0.057
Human
axon development GO:0061564 166 0.056
Fly
regulation of cellular biosynthetic process GO:0031326 245 0.055
Human Mouse Rat
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.055
Human
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.055
nitric oxide biosynthetic process GO:0006809 2 0.055
Human
carboxylic acid metabolic process GO:0019752 22 0.054
Human
positive regulation of signaling GO:0023056 56 0.054
Human
cellular component assembly GO:0022607 170 0.053
Human Rat Worm
regulation of reactive oxygen species metabolic process GO:2000377 2 0.053
Rat Fly
negative regulation of signaling GO:0023057 96 0.053
negative regulation of cell communication GO:0010648 96 0.053
phosphate containing compound metabolic process GO:0006796 108 0.053
Human Mouse Rat Fly
cell morphogenesis GO:0000902 289 0.052
Fly
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.052
negative regulation of biosynthetic process GO:0009890 55 0.052
muscle cell differentiation GO:0042692 139 0.052
Fly
embryonic organ development GO:0048568 381 0.052
Zebrafish
heterocycle biosynthetic process GO:0018130 215 0.052
Human
organonitrogen compound metabolic process GO:1901564 74 0.051
system process GO:0003008 185 0.050
modification dependent protein catabolic process GO:0019941 3 0.050
brain development GO:0007420 293 0.050
pyruvate metabolic process GO:0006090 1 0.050
Human
developmental growth GO:0048589 166 0.049
cell projection organization GO:0030030 284 0.049
Fly
endothelial cell development GO:0001885 12 0.049
insulin like growth factor receptor signaling pathway GO:0048009 4 0.049
Zebrafish
activation of mapk activity GO:0000187 3 0.049
Human
hormone transport GO:0009914 2 0.048
negative regulation of intracellular protein transport GO:0090317 3 0.048
Worm
reactive oxygen species biosynthetic process GO:1903409 1 0.048
cognition GO:0050890 1 0.048
single organism biosynthetic process GO:0044711 71 0.048
Human Mouse
female gonad development GO:0008585 4 0.047
Fly
nuclear import GO:0051170 3 0.047
Worm
regeneration GO:0031099 91 0.047
Zebrafish
muscle structure development GO:0061061 196 0.047
Fly
negative regulation of protein phosphorylation GO:0001933 4 0.047
Rat
positive regulation of cellular catabolic process GO:0031331 3 0.047
Human
immune system development GO:0002520 191 0.046
regulation of protein catabolic process GO:0042176 1 0.046
cellular response to nutrient levels GO:0031669 2 0.046
Worm
negative regulation of tor signaling GO:0032007 2 0.045
cell projection morphogenesis GO:0048858 244 0.045
Fly
regulation of blood circulation GO:1903522 32 0.045
negative regulation of macromolecule metabolic process GO:0010605 76 0.044
Zebrafish Rat
organelle assembly GO:0070925 110 0.044
Worm
nitrogen compound metabolic process GO:0006807 319 0.044
Human
cellular response to chemical stimulus GO:0070887 157 0.044
Human Mouse Rat Fly
regulation of dendrite development GO:0050773 3 0.044
transmission of nerve impulse GO:0019226 19 0.044
nucleobase containing compound biosynthetic process GO:0034654 205 0.043
Human
positive regulation of carbohydrate metabolic process GO:0045913 1 0.043
Human Mouse
post embryonic organ development GO:0048569 4 0.043
regulation of stem cell proliferation GO:0072091 2 0.043
negative regulation of cytokine production GO:0001818 1 0.043
peptidyl lysine acetylation GO:0018394 2 0.043
positive regulation of developmental process GO:0051094 50 0.042
Human Worm Fly
regulation of response to nutrient levels GO:0032107 1 0.042
Worm
response to lipid GO:0033993 60 0.042
Rat
negative regulation of metabolic process GO:0009892 86 0.042
Zebrafish Rat Fly
developmental cell growth GO:0048588 52 0.041
Fly
hydrogen peroxide metabolic process GO:0042743 2 0.041
Rat
cellular amine metabolic process GO:0044106 2 0.041
stem cell proliferation GO:0072089 4 0.041
locomotory behavior GO:0007626 34 0.041
Fly
positive regulation of immune effector process GO:0002699 3 0.041
regulation of behavior GO:0050795 24 0.041
Fly
positive regulation of biosynthetic process GO:0009891 68 0.040
Human Mouse Rat
response to estrogen GO:0043627 27 0.040
Rat
programmed cell death GO:0012501 119 0.040
Zebrafish
regulation of response to oxidative stress GO:1902882 2 0.040
Worm
ubiquitin dependent protein catabolic process GO:0006511 3 0.040
cellular localization GO:0051641 97 0.040
Worm
adult behavior GO:0030534 2 0.040
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.039
sex determination GO:0007530 1 0.039
Mouse
cellular nitrogen compound metabolic process GO:0034641 290 0.039
Human
regulation of hormone secretion GO:0046883 2 0.039
ameboidal type cell migration GO:0001667 143 0.039
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.038
Human Zebrafish Mouse Rat Fly
modulation by virus of host morphology or physiology GO:0019048 1 0.038
Human
hypothalamus cell differentiation GO:0021979 4 0.038
regulation of embryonic development GO:0045995 47 0.038
Human
negative regulation of rna metabolic process GO:0051253 48 0.038
autophagy GO:0006914 4 0.037
Worm Fly
camera type eye development GO:0043010 222 0.037
Zebrafish
heterocycle metabolic process GO:0046483 290 0.037
Human
digestive system development GO:0055123 289 0.037
Mouse
internal protein amino acid acetylation GO:0006475 2 0.036
transmembrane transport GO:0055085 120 0.036
epithelial cell development GO:0002064 42 0.036
internal peptidyl lysine acetylation GO:0018393 2 0.036
protein localization to nucleus GO:0034504 3 0.036
Worm
cellular protein catabolic process GO:0044257 4 0.036
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.036
response to ketone GO:1901654 1 0.036
Rat
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.036
Fly
establishment of localization in cell GO:0051649 77 0.036
Worm
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.035
response to endogenous stimulus GO:0009719 83 0.035
Human Mouse Rat Fly
glucose homeostasis GO:0042593 1 0.035
Human Rat
nucleic acid metabolic process GO:0090304 244 0.035
Human
death GO:0016265 121 0.035
Zebrafish
regulation of cellular component size GO:0032535 30 0.035
Fly
lipid metabolic process GO:0006629 52 0.035
Fly
response to glucocorticoid GO:0051384 1 0.035
Rat
ion transport GO:0006811 114 0.035
circadian behavior GO:0048512 5 0.035
Fly
regulation of muscle contraction GO:0006937 3 0.034
phosphatidylinositol mediated signaling GO:0048015 2 0.034
regulation of cellular amino acid metabolic process GO:0006521 0 0.034
protein acetylation GO:0006473 2 0.034
oxoacid metabolic process GO:0043436 31 0.034
Human
regulation of glucose transport GO:0010827 1 0.034
Human
negative regulation of cellular biosynthetic process GO:0031327 55 0.033
regulation of protein ubiquitination GO:0031396 3 0.033
positive regulation of macromolecule metabolic process GO:0010604 93 0.032
Human Mouse Rat
guanosine containing compound metabolic process GO:1901068 4 0.032
tube morphogenesis GO:0035239 349 0.032
Zebrafish
response to vitamin GO:0033273 3 0.032
Rat
cellular protein modification process GO:0006464 100 0.032
Human Mouse Rat Fly
regulation of cell development GO:0060284 100 0.032
cellular response to hormone stimulus GO:0032870 39 0.032
Human Mouse Rat Fly
modification dependent macromolecule catabolic process GO:0043632 3 0.032
cellular aromatic compound metabolic process GO:0006725 295 0.032
Human
positive regulation of molecular function GO:0044093 33 0.032
Human
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.032
Worm
enzyme linked receptor protein signaling pathway GO:0007167 106 0.032
Human Zebrafish Mouse Rat Fly
hormone secretion GO:0046879 2 0.031
actin filament based process GO:0030029 64 0.031
fatty acid transport GO:0015908 1 0.031
regulation of nucleocytoplasmic transport GO:0046822 2 0.031
Worm
axon guidance GO:0007411 86 0.031
Fly
protein secretion GO:0009306 1 0.031
positive regulation of cell cycle GO:0045787 3 0.031
Human Mouse
wound healing GO:0042060 90 0.031
Zebrafish
regulation of cellular ketone metabolic process GO:0010565 7 0.031
hemopoiesis GO:0030097 183 0.031
sensory organ morphogenesis GO:0090596 200 0.031
Zebrafish
regulation of metal ion transport GO:0010959 4 0.030
neuron neuron synaptic transmission GO:0007270 1 0.030
response to topologically incorrect protein GO:0035966 2 0.030
metal ion transport GO:0030001 58 0.030
digestive tract development GO:0048565 265 0.030
positive regulation of cell communication GO:0010647 56 0.030
Human
apical junction assembly GO:0043297 1 0.030
germ line stem cell maintenance GO:0030718 2 0.030
cellular protein metabolic process GO:0044267 129 0.030
Human Zebrafish Mouse Rat Fly
protein kinase b signaling GO:0043491 9 0.030
Human
phagocytosis GO:0006909 3 0.030
amine metabolic process GO:0009308 2 0.030
skeletal system development GO:0001501 181 0.029
growth GO:0040007 174 0.029
carbohydrate homeostasis GO:0033500 1 0.029
Human Rat
peptide transport GO:0015833 1 0.029
positive regulation of gliogenesis GO:0014015 2 0.028
positive regulation of cell adhesion GO:0045785 1 0.028
cell adhesion GO:0007155 40 0.028
regulation of synapse organization GO:0050807 3 0.028
synaptic growth at neuromuscular junction GO:0051124 2 0.028
angiogenesis GO:0001525 158 0.028
response to hormone GO:0009725 48 0.028
Human Mouse Rat Fly
protein import GO:0017038 3 0.028
Worm
entrainment of circadian clock GO:0009649 2 0.028
regulation of cellular amine metabolic process GO:0033238 0 0.028
cellular response to radiation GO:0071478 4 0.028
regulation of tube size GO:0035150 2 0.028
response to light stimulus GO:0009416 46 0.028
regulation of neurogenesis GO:0050767 87 0.028
regulation of response to cytokine stimulus GO:0060759 3 0.027
negative regulation of intracellular transport GO:0032387 3 0.027
Worm
regulation of nervous system development GO:0051960 90 0.027
anion transport GO:0006820 38 0.027
stem cell maintenance GO:0019827 4 0.027
wnt signaling pathway GO:0016055 80 0.027
macroautophagy GO:0016236 1 0.027
Worm
organic acid metabolic process GO:0006082 31 0.027
Human
neuron remodeling GO:0016322 1 0.027
Fly
regulation of anatomical structure morphogenesis GO:0022603 130 0.027
central nervous system neuron differentiation GO:0021953 74 0.027
Zebrafish
cell part morphogenesis GO:0032990 246 0.027
Fly
neuron projection guidance GO:0097485 86 0.027
Fly
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.026
pigment cell differentiation GO:0050931 38 0.026
Zebrafish
regulation of dendrite morphogenesis GO:0048814 3 0.026
cellular ketone metabolic process GO:0042180 11 0.026
morphogenesis of an epithelium GO:0002009 333 0.026
response to drug GO:0042493 3 0.026
regulation of cell size GO:0008361 29 0.026
Fly
epidermis development GO:0008544 48 0.026
Mouse
positive regulation of catabolic process GO:0009896 4 0.026
Human
protein metabolic process GO:0019538 183 0.026
Human Zebrafish Mouse Rat Fly
liver development GO:0001889 96 0.025
nucleobase containing compound metabolic process GO:0006139 274 0.025
Human
meiotic cell cycle process GO:1903046 3 0.025
protein modification process GO:0036211 100 0.025
Human Mouse Rat Fly
regulation of protein kinase b signaling GO:0051896 8 0.025
Human
positive regulation of glucose import GO:0046326 1 0.025
Human
meiotic nuclear division GO:0007126 4 0.025
immune effector process GO:0002252 23 0.025
regulation of autophagy GO:0010506 3 0.025
Worm Fly
cellular response to stress GO:0033554 62 0.025
Worm Fly
regulation of inflammatory response GO:0050727 2 0.025
negative regulation of signal transduction GO:0009968 94 0.025
regulation of synapse assembly GO:0051963 3 0.025
multi organism process GO:0051704 134 0.024
Human Zebrafish Worm Fly
cell morphogenesis involved in differentiation GO:0000904 195 0.024
Fly
positive regulation of inflammatory response GO:0050729 1 0.024
positive regulation of stress activated mapk cascade GO:0032874 3 0.024
dicarboxylic acid transport GO:0006835 1 0.024
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.024
regulation of cytoplasmic transport GO:1903649 4 0.024
Worm
cellular response to endogenous stimulus GO:0071495 68 0.024
Human Mouse Rat Fly
calcium ion import GO:0070509 4 0.024
response to steroid hormone GO:0048545 35 0.023
Rat
regulation of protein targeting GO:1903533 2 0.023
Worm
transcription from rna polymerase ii promoter GO:0006366 80 0.023
cell killing GO:0001906 2 0.023
blood circulation GO:0008015 87 0.023
phosphorus metabolic process GO:0006793 109 0.023
Human Mouse Rat Fly
regulation of programmed cell death GO:0043067 101 0.023
Zebrafish
cellular response to molecule of bacterial origin GO:0071219 3 0.023
macromolecule modification GO:0043412 111 0.022
Human Mouse Rat Fly
neuroblast proliferation GO:0007405 2 0.022
vasculogenesis GO:0001570 41 0.022
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.022
regulation of immune system process GO:0002682 34 0.022
heart development GO:0007507 313 0.022
Human Zebrafish
actin cytoskeleton organization GO:0030036 63 0.022
embryonic heart tube development GO:0035050 133 0.022
protein acylation GO:0043543 3 0.022
regulation of cell differentiation GO:0045595 142 0.022
ion transmembrane transport GO:0034220 91 0.022
regulation of nucleoside metabolic process GO:0009118 2 0.022
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.022
regionalization GO:0003002 274 0.021
Zebrafish
taxis GO:0042330 109 0.021
Fly
single organism behavior GO:0044708 24 0.021
Fly
epithelial cell differentiation GO:0030855 116 0.021
regulation of rho protein signal transduction GO:0035023 2 0.021
water homeostasis GO:0030104 4 0.021
positive regulation of cell activation GO:0050867 1 0.021
regulation of molecular function GO:0065009 70 0.021
Human Zebrafish Rat
cellular component biogenesis GO:0044085 178 0.021
Human Rat Worm
regulation of cell shape GO:0008360 1 0.021
gtp metabolic process GO:0046039 4 0.021
cell cycle g1 s phase transition GO:0044843 1 0.021
negative regulation of response to cytokine stimulus GO:0060761 2 0.021
regulation of developmental growth GO:0048638 38 0.021
Human Worm Fly
cell migration involved in gastrulation GO:0042074 79 0.021
regulation of blood pressure GO:0008217 1 0.021
cellular respiration GO:0045333 3 0.021
regulation of protein localization to nucleus GO:1900180 2 0.020
Worm
g1 s transition of mitotic cell cycle GO:0000082 1 0.020
regulation of neurological system process GO:0031644 2 0.020
reproductive process GO:0022414 40 0.020
Zebrafish Mouse Worm Fly
regulation of receptor activity GO:0010469 2 0.020
phototransduction GO:0007602 2 0.020
multi organism cellular process GO:0044764 2 0.020
Human
carbohydrate transport GO:0008643 13 0.020
Human
regulation of apoptotic process GO:0042981 98 0.020
Zebrafish
nitric oxide metabolic process GO:0046209 2 0.020
Human
response to nutrient GO:0007584 3 0.020
Rat
positive regulation of signal transduction GO:0009967 56 0.020
Human
regulation of cytokine mediated signaling pathway GO:0001959 3 0.020
intracellular transport GO:0046907 32 0.020
Worm
androgen metabolic process GO:0008209 2 0.020
heart looping GO:0001947 94 0.020
positive regulation of cellular carbohydrate metabolic process GO:0010676 1 0.019
Human Mouse
inositol lipid mediated signaling GO:0048017 2 0.019
cell growth GO:0016049 57 0.019
Fly
cell matrix adhesion GO:0007160 4 0.019
positive regulation of metabolic process GO:0009893 108 0.019
Human Mouse Rat
regulation of skeletal muscle tissue development GO:0048641 4 0.019
regulation of transport GO:0051049 45 0.019
Human Rat Worm
multicellular organismal response to stress GO:0033555 2 0.019
dorsal ventral pattern formation GO:0009953 125 0.019
ossification GO:0001503 23 0.019
regulation of cell activation GO:0050865 1 0.019
negative regulation of wnt signaling pathway GO:0030178 30 0.019
phosphorylation GO:0016310 69 0.019
Human Mouse Rat Fly
circadian rhythm GO:0007623 19 0.019
Fly
regulation of blood vessel size GO:0050880 2 0.019
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.019
macromolecular complex subunit organization GO:0043933 74 0.018
Human Rat
muscle cell development GO:0055001 115 0.018
regulation of myotube differentiation GO:0010830 2 0.018
b cell activation GO:0042113 2 0.018
embryonic organ morphogenesis GO:0048562 274 0.018
Zebrafish
positive regulation of cell killing GO:0031343 2 0.018
muscle organ development GO:0007517 101 0.018
ovulation cycle process GO:0022602 2 0.018
synaptic vesicle transport GO:0048489 1 0.018
negative regulation of protein complex assembly GO:0031333 1 0.018
establishment of endothelial barrier GO:0061028 3 0.018
positive regulation of cellular component biogenesis GO:0044089 3 0.018
regulation of protein complex assembly GO:0043254 3 0.018
cellular amino acid metabolic process GO:0006520 7 0.018
biological adhesion GO:0022610 40 0.018
regulation of cellular component movement GO:0051270 55 0.018
Human
positive regulation of muscle organ development GO:0048636 1 0.018
regulation of cellular component organization GO:0051128 86 0.018
Human Mouse Worm Fly
negative regulation of apoptotic process GO:0043066 55 0.018
Zebrafish
negative regulation of transcription dna templated GO:0045892 45 0.017
positive regulation of striated muscle tissue development GO:0045844 1 0.017
monosaccharide transport GO:0015749 6 0.017
Human
intracellular receptor signaling pathway GO:0030522 30 0.017
regulation of hormone levels GO:0010817 21 0.017
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.017
regulation of wound healing GO:0061041 2 0.017
regulation of growth GO:0040008 42 0.017
Human Worm Fly
startle response GO:0001964 4 0.017
cation transport GO:0006812 81 0.017
spermatid development GO:0007286 2 0.017
nuclear export GO:0051168 1 0.017
regulation of ph GO:0006885 3 0.017
regulation of wnt signaling pathway GO:0030111 53 0.017
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 4 0.017
Human
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.017
negative regulation of cellular metabolic process GO:0031324 77 0.017
Zebrafish Rat Fly
positive regulation of cellular metabolic process GO:0031325 94 0.017
Human Mouse Rat
sensory perception of chemical stimulus GO:0007606 3 0.017
protein complex disassembly GO:0043241 1 0.017
gastrulation GO:0007369 208 0.017
negative regulation of protein import into nucleus GO:0042308 2 0.017
Worm
cell aging GO:0007569 2 0.017
gtp catabolic process GO:0006184 2 0.017
cellular response to dna damage stimulus GO:0006974 24 0.017
Fly
response to temperature stimulus GO:0009266 15 0.017
Worm
regulation of phosphorus metabolic process GO:0051174 43 0.017
Human Rat
circulatory system process GO:0003013 87 0.016
dna templated transcription elongation GO:0006354 3 0.016
regulation of protein metabolic process GO:0051246 56 0.016
Human Zebrafish Rat
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.016
macromolecular complex assembly GO:0065003 35 0.016
Human Rat
interspecies interaction between organisms GO:0044419 4 0.016
Human
guanosine containing compound catabolic process GO:1901069 2 0.016
positive regulation of muscle tissue development GO:1901863 1 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.016
fin development GO:0033333 77 0.016
regulation of cell motility GO:2000145 46 0.016
Human
establishment or maintenance of polarity of embryonic epithelium GO:0016332 2 0.016
regulation of organelle assembly GO:1902115 4 0.016
Worm
positive regulation of dna metabolic process GO:0051054 1 0.016
Human
apoptotic process GO:0006915 116 0.016
Zebrafish
regulation of neuron projection development GO:0010975 40 0.016
protein dephosphorylation GO:0006470 3 0.016
toll like receptor signaling pathway GO:0002224 4 0.016
cellular component assembly involved in morphogenesis GO:0010927 107 0.016

insra disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.043
nervous system disease DOID:863 0 0.033
cancer DOID:162 0 0.023
disease of cellular proliferation DOID:14566 0 0.023
disease of metabolism DOID:0014667 0 0.020
Human
inherited metabolic disorder DOID:655 0 0.020
Human