Danio rerio

0 known processes

bin2b

bridging integrator 2b

(Aliases: bin2l,wu:fi05e01,zgc:55758,BIN2)

bin2b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
membrane fusion GO:0061025 2 0.101
positive regulation of protein complex assembly GO:0031334 2 0.066
regulation of protein complex assembly GO:0043254 3 0.064
single organism transport GO:0044765 206 0.062
regulation of cell projection assembly GO:0060491 4 0.055
single organism organelle organization GO:1902589 199 0.055
cortical actin cytoskeleton organization GO:0030866 1 0.055
single organism membrane fusion GO:0044801 2 0.053
cellular nitrogen compound metabolic process GO:0034641 290 0.053
regulation of cell shape GO:0008360 1 0.053
organelle organization GO:0006996 227 0.053
organelle fusion GO:0048284 3 0.053
protein polymerization GO:0051258 4 0.052
heterocycle metabolic process GO:0046483 290 0.051
cytokinesis GO:0000910 3 0.050
cellular component assembly GO:0022607 170 0.049
phagocytosis GO:0006909 3 0.049
cortical cytoskeleton organization GO:0030865 1 0.049
organic cyclic compound metabolic process GO:1901360 301 0.049
positive regulation of cellular component biogenesis GO:0044089 3 0.048
mitochondrion organization GO:0007005 4 0.048
nitrogen compound metabolic process GO:0006807 319 0.046
biosynthetic process GO:0009058 294 0.046
cellular aromatic compound metabolic process GO:0006725 295 0.043
regulation of filopodium assembly GO:0051489 2 0.041
establishment of localization GO:0051234 244 0.040
single organism localization GO:1902578 225 0.037
cellular component morphogenesis GO:0032989 336 0.037
nucleobase containing compound metabolic process GO:0006139 274 0.036
positive regulation of transport GO:0051050 2 0.036
meiotic cell cycle process GO:1903046 3 0.035
organic substance biosynthetic process GO:1901576 289 0.035
nucleic acid metabolic process GO:0090304 244 0.035
cell projection assembly GO:0030031 64 0.034
immune system process GO:0002376 241 0.034
establishment of protein localization to organelle GO:0072594 4 0.033
guanosine containing compound metabolic process GO:1901068 4 0.033
nuclear transport GO:0051169 4 0.033
cell cycle GO:0007049 93 0.033
larval development GO:0002164 2 0.033
aging GO:0007568 2 0.032
actin polymerization or depolymerization GO:0008154 2 0.032
mitotic cell cycle GO:0000278 64 0.031
positive regulation of cytoskeleton organization GO:0051495 3 0.031
central nervous system development GO:0007417 387 0.031
stem cell proliferation GO:0072089 4 0.030
transport GO:0006810 220 0.030
regulation of cytokine production GO:0001817 3 0.030
spindle assembly GO:0051225 2 0.029
positive regulation of cellular process GO:0048522 201 0.029
regulation of nitrogen compound metabolic process GO:0051171 251 0.029
phosphate containing compound metabolic process GO:0006796 108 0.029
nucleobase containing compound biosynthetic process GO:0034654 205 0.028
nucleocytoplasmic transport GO:0006913 4 0.028
single organism metabolic process GO:0044710 217 0.027
regulation of biological quality GO:0065008 263 0.027
heterocycle biosynthetic process GO:0018130 215 0.027
regulation of protein polymerization GO:0032271 2 0.027
cellular biosynthetic process GO:0044249 286 0.026
lamellipodium assembly GO:0030032 1 0.026
organonitrogen compound metabolic process GO:1901564 74 0.026
positive regulation of protein polymerization GO:0032273 2 0.026
multicellular organism growth GO:0035264 4 0.025
cell projection organization GO:0030030 284 0.025
cellular ketone metabolic process GO:0042180 11 0.025
cell morphogenesis GO:0000902 289 0.025
extrinsic apoptotic signaling pathway GO:0097191 3 0.025
specification of symmetry GO:0009799 204 0.025
lipid storage GO:0019915 1 0.025
regulation of cytoplasmic transport GO:1903649 4 0.024
regulation of multicellular organism growth GO:0040014 4 0.024
regulation of developmental process GO:0050793 247 0.024
regulation of cellular amine metabolic process GO:0033238 0 0.024
organelle assembly GO:0070925 110 0.024
small molecule metabolic process GO:0044281 77 0.024
gtp metabolic process GO:0046039 4 0.024
stem cell maintenance GO:0019827 4 0.024
regulation of metabolic process GO:0019222 359 0.023
positive regulation of cellular catabolic process GO:0031331 3 0.023
leukocyte proliferation GO:0070661 1 0.023
cognition GO:0050890 1 0.023
regulation of synapse assembly GO:0051963 3 0.023
positive regulation of biological process GO:0048518 253 0.023
vacuolar transport GO:0007034 2 0.023
rna modification GO:0009451 2 0.022
hematopoietic or lymphoid organ development GO:0048534 191 0.022
cellular component movement GO:0006928 335 0.022
positive regulation of catabolic process GO:0009896 4 0.022
cellular amino acid metabolic process GO:0006520 7 0.022
phosphorus metabolic process GO:0006793 109 0.022
cytoskeleton dependent cytokinesis GO:0061640 3 0.022
cellular macromolecule metabolic process GO:0044260 391 0.022
rna metabolic process GO:0016070 219 0.022
protein localization to nucleus GO:0034504 3 0.022
morphogenesis of an epithelium GO:0002009 333 0.021
embryo development ending in birth or egg hatching GO:0009792 271 0.021
sensory organ development GO:0007423 393 0.021
cellular localization GO:0051641 97 0.021
negative regulation of nuclear division GO:0051784 3 0.021
programmed cell death GO:0012501 119 0.021
cellular amine metabolic process GO:0044106 2 0.021
cellular component biogenesis GO:0044085 178 0.021
guanosine containing compound catabolic process GO:1901069 2 0.020
amine metabolic process GO:0009308 2 0.020
regulation of cellular amino acid metabolic process GO:0006521 0 0.020
cell projection morphogenesis GO:0048858 244 0.020
positive regulation of cell cycle GO:0045787 3 0.020
regulation of establishment of protein localization GO:0070201 4 0.020
macromolecular complex assembly GO:0065003 35 0.020
ribonucleoside monophosphate catabolic process GO:0009158 4 0.020
autophagy GO:0006914 4 0.020
localization of cell GO:0051674 244 0.020
nucleoside monophosphate catabolic process GO:0009125 4 0.020
phagocytosis engulfment GO:0006911 1 0.020
death GO:0016265 121 0.020
positive regulation of cytokine production GO:0001819 2 0.019
synaptic growth at neuromuscular junction GO:0051124 2 0.019
neuroblast proliferation GO:0007405 2 0.019
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.019
signal transduction GO:0007165 455 0.019
apoptotic process GO:0006915 116 0.019
cellular macromolecule biosynthetic process GO:0034645 224 0.019
protein localization to plasma membrane GO:0072659 1 0.019
mitotic dna damage checkpoint GO:0044773 4 0.019
regulation of cellular component organization GO:0051128 86 0.019
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.019
regulation of synapse organization GO:0050807 3 0.019
generation of neurons GO:0048699 385 0.019
negative regulation of cellular process GO:0048523 283 0.018
b cell activation GO:0042113 2 0.018
eye development GO:0001654 277 0.018
aromatic compound biosynthetic process GO:0019438 217 0.018
exocytosis GO:0006887 1 0.018
positive regulation of cellular amine metabolic process GO:0033240 0 0.018
endosomal transport GO:0016197 2 0.018
cellular component disassembly GO:0022411 1 0.018
transcription dna templated GO:0006351 181 0.018
cell motility GO:0048870 244 0.017
regulation of cell activation GO:0050865 1 0.017
organic acid metabolic process GO:0006082 31 0.017
response to external stimulus GO:0009605 264 0.017
gene expression GO:0010467 252 0.017
cell death GO:0008219 121 0.017
regulation of binding GO:0051098 3 0.017
macromolecule biosynthetic process GO:0009059 227 0.017
macromolecular complex subunit organization GO:0043933 74 0.017
spermatid development GO:0007286 2 0.017
mononuclear cell proliferation GO:0032943 1 0.017
maintenance of location GO:0051235 4 0.016
cytokinetic process GO:0032506 2 0.016
protein complex biogenesis GO:0070271 30 0.016
nuclear import GO:0051170 3 0.016
cellular nitrogen compound biosynthetic process GO:0044271 218 0.016
regulation of programmed cell death GO:0043067 101 0.016
locomotion GO:0040011 313 0.016
chordate embryonic development GO:0043009 271 0.016
mitotic dna integrity checkpoint GO:0044774 4 0.016
protein stabilization GO:0050821 2 0.016
neuron differentiation GO:0030182 353 0.016
regulation of protein localization to nucleus GO:1900180 2 0.016
heart development GO:0007507 313 0.016
protein targeting to nucleus GO:0044744 3 0.016
gtp catabolic process GO:0006184 2 0.016
lateral inhibition GO:0046331 1 0.016
golgi organization GO:0007030 1 0.016
positive regulation of cell activation GO:0050867 1 0.016
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.016
oxoacid metabolic process GO:0043436 31 0.016
regulation of cellular metabolic process GO:0031323 320 0.015
positive regulation of gtpase activity GO:0043547 1 0.015
secondary metabolic process GO:0019748 3 0.015
taxis GO:0042330 109 0.015
organic cyclic compound biosynthetic process GO:1901362 223 0.015
g1 s transition of mitotic cell cycle GO:0000082 1 0.015
membrane invagination GO:0010324 1 0.015
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.015
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.015
regulation of nucleotide catabolic process GO:0030811 2 0.015
regulation of signaling GO:0023051 235 0.015
adult behavior GO:0030534 2 0.015
regulation of purine nucleotide catabolic process GO:0033121 2 0.015
immune system development GO:0002520 191 0.015
brain development GO:0007420 293 0.015
cell part morphogenesis GO:0032990 246 0.015
cellular protein catabolic process GO:0044257 4 0.015
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.015
actin filament based process GO:0030029 64 0.015
negative regulation of biological process GO:0048519 304 0.015
cellular response to external stimulus GO:0071496 2 0.015
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.015
modification dependent macromolecule catabolic process GO:0043632 3 0.015
determination of bilateral symmetry GO:0009855 204 0.015
cellular response to chemical stimulus GO:0070887 157 0.014
cilium assembly GO:0042384 58 0.014
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.014
regulation of anatomical structure morphogenesis GO:0022603 130 0.014
cell substrate adhesion GO:0031589 4 0.014
melanin metabolic process GO:0006582 2 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.014
stem cell division GO:0017145 1 0.014
positive regulation of gtp catabolic process GO:0033126 1 0.014
protein metabolic process GO:0019538 183 0.014
g2 dna damage checkpoint GO:0031572 3 0.014
response to drug GO:0042493 3 0.014
cell surface receptor signaling pathway GO:0007166 325 0.014
regulation of cell death GO:0010941 103 0.014
regulation of rna biosynthetic process GO:2001141 213 0.014
positive regulation of apoptotic signaling pathway GO:2001235 1 0.014
germ line stem cell maintenance GO:0030718 2 0.014
protein dephosphorylation GO:0006470 3 0.014
regulation of apoptotic process GO:0042981 98 0.014
glycerophospholipid biosynthetic process GO:0046474 1 0.014
peptidyl serine phosphorylation GO:0018105 1 0.014
response to external biotic stimulus GO:0043207 97 0.014
purine nucleoside monophosphate catabolic process GO:0009128 4 0.014
interspecies interaction between organisms GO:0044419 4 0.014
regulation of nucleoside metabolic process GO:0009118 2 0.014
peptidyl lysine acetylation GO:0018394 2 0.013
positive regulation of secretion GO:0051047 1 0.013
chemosensory behavior GO:0007635 1 0.013
response to biotic stimulus GO:0009607 97 0.013
regulation of protein transport GO:0051223 3 0.013
rna biosynthetic process GO:0032774 181 0.013
cellular response to starvation GO:0009267 1 0.013
response to stress GO:0006950 263 0.013
lymphocyte proliferation GO:0046651 1 0.013
cilium morphogenesis GO:0060271 85 0.013
positive regulation of secretion by cell GO:1903532 1 0.013
regulation of gtpase activity GO:0043087 2 0.013
meiotic nuclear division GO:0007126 4 0.013
ubiquitin dependent protein catabolic process GO:0006511 3 0.013
cell cycle process GO:0022402 53 0.013
multi organism process GO:0051704 134 0.013
mitotic cell cycle embryonic GO:0045448 2 0.013
tube morphogenesis GO:0035239 349 0.013
peptidyl serine modification GO:0018209 2 0.013
neuron development GO:0048666 262 0.013
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.013
regulation of rna metabolic process GO:0051252 224 0.013
cellular macromolecular complex assembly GO:0034622 24 0.012
cellular response to extracellular stimulus GO:0031668 2 0.012
regulation of gene expression GO:0010468 265 0.012
positive regulation of nucleotide catabolic process GO:0030813 1 0.012
regionalization GO:0003002 274 0.012
macromolecule modification GO:0043412 111 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.012
cilium organization GO:0044782 71 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.012
proteasomal protein catabolic process GO:0010498 2 0.012
developmental growth GO:0048589 166 0.012
growth GO:0040007 174 0.012
microtubule based process GO:0007017 60 0.012
carboxylic acid metabolic process GO:0019752 22 0.012
embryonic organ development GO:0048568 381 0.012
internal protein amino acid acetylation GO:0006475 2 0.012
cellular protein metabolic process GO:0044267 129 0.012
regulation of response to cytokine stimulus GO:0060759 3 0.012
positive regulation of stress activated mapk cascade GO:0032874 3 0.012
camera type eye development GO:0043010 222 0.012
response to chemical GO:0042221 320 0.012
positive regulation of nucleoside metabolic process GO:0045979 1 0.012
regulation of mrna processing GO:0050684 3 0.012
developmental programmed cell death GO:0010623 4 0.012
positive regulation of map kinase activity GO:0043406 3 0.012
regulation of nucleic acid templated transcription GO:1903506 213 0.012
regulation of stem cell differentiation GO:2000736 4 0.012
b cell mediated immunity GO:0019724 3 0.012
negative regulation of secretion by cell GO:1903531 2 0.012
gland development GO:0048732 143 0.012
regulation of gtp catabolic process GO:0033124 2 0.012
regulation of macromolecule biosynthetic process GO:0010556 225 0.012
cellular response to lipopolysaccharide GO:0071222 3 0.012
digestive system development GO:0055123 289 0.012
single organism nuclear import GO:1902593 3 0.012
protein import GO:0017038 3 0.012
nucleic acid templated transcription GO:0097659 181 0.012
blood vessel development GO:0001568 246 0.012
regulation of protein catabolic process GO:0042176 1 0.012
mitotic cell cycle process GO:1903047 48 0.012
meiotic chromosome segregation GO:0045132 3 0.012
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.012
regulation of nucleocytoplasmic transport GO:0046822 2 0.012
muscle structure development GO:0061061 196 0.011
regulation of cellular biosynthetic process GO:0031326 245 0.011
regulation of macromolecule metabolic process GO:0060255 317 0.011
cell migration GO:0016477 237 0.011
viral process GO:0016032 1 0.011
regulation of meiotic cell cycle GO:0051445 1 0.011
regulation of stem cell proliferation GO:0072091 2 0.011
mitotic g2 m transition checkpoint GO:0044818 3 0.011
regulation of neural precursor cell proliferation GO:2000177 3 0.011
myotube differentiation GO:0014902 45 0.011
protein secretion GO:0009306 1 0.011
regulation of cellular ketone metabolic process GO:0010565 7 0.011
regulation of protein targeting GO:1903533 2 0.011
regulation of intracellular protein transport GO:0033157 3 0.011
hepaticobiliary system development GO:0061008 98 0.011
cell adhesion mediated by integrin GO:0033627 1 0.011
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.011
actin filament polymerization GO:0030041 2 0.011
negative regulation of protein phosphorylation GO:0001933 4 0.011
glial cell migration GO:0008347 3 0.011
actin cytoskeleton organization GO:0030036 63 0.011
production of molecular mediator of immune response GO:0002440 2 0.011
positive regulation of cell adhesion GO:0045785 1 0.011
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.011
cellular response to nutrient levels GO:0031669 2 0.011
head development GO:0060322 303 0.011
striated muscle cell differentiation GO:0051146 129 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
cytoskeleton organization GO:0007010 96 0.011
cytosolic calcium ion transport GO:0060401 3 0.011
determination of left right symmetry GO:0007368 179 0.011
dna biosynthetic process GO:0071897 3 0.011
tissue remodeling GO:0048771 4 0.011
somatic muscle development GO:0007525 4 0.010
positive regulation of immune effector process GO:0002699 3 0.010
regulation of organelle assembly GO:1902115 4 0.010
peptide transport GO:0015833 1 0.010
meiosis i GO:0007127 1 0.010
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.010
protein acetylation GO:0006473 2 0.010
histone phosphorylation GO:0016572 2 0.010
cell matrix adhesion GO:0007160 4 0.010
regulation of microtubule cytoskeleton organization GO:0070507 3 0.010
microtubule organizing center organization GO:0031023 1 0.010
regulation of protein ubiquitination GO:0031396 3 0.010
homeostatic process GO:0042592 142 0.010
negative regulation of defense response GO:0031348 2 0.010
regulation of blood pressure GO:0008217 1 0.010
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.010
hemopoiesis GO:0030097 183 0.010
regulation of cell matrix adhesion GO:0001952 1 0.010
somatic stem cell maintenance GO:0035019 1 0.010
protein import into nucleus GO:0006606 3 0.010
segmentation GO:0035282 97 0.010

bin2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.042
nervous system disease DOID:863 0 0.014
disease of metabolism DOID:0014667 0 0.014
disease of cellular proliferation DOID:14566 0 0.013
inherited metabolic disorder DOID:655 0 0.013
immune system disease DOID:2914 0 0.011
cancer DOID:162 0 0.011
organ system cancer DOID:0050686 0 0.011