Danio rerio

0 known processes

LOC100150924

DNA polymerase subunit gamma-1-like

LOC100150924 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
organelle assembly GO:0070925 110 0.626
digestive system development GO:0055123 289 0.564
digestive tract development GO:0048565 265 0.301
signal transduction GO:0007165 455 0.295
chordate embryonic development GO:0043009 271 0.277
embryonic organ morphogenesis GO:0048562 274 0.276
cellular component movement GO:0006928 335 0.236
cellular component morphogenesis GO:0032989 336 0.216
regulation of metabolic process GO:0019222 359 0.213
regulation of primary metabolic process GO:0080090 311 0.207
central nervous system development GO:0007417 387 0.200
renal system process involved in regulation of blood volume GO:0001977 1 0.197
heart development GO:0007507 313 0.191
organelle organization GO:0006996 227 0.175
determination of bilateral symmetry GO:0009855 204 0.175
tube morphogenesis GO:0035239 349 0.174
negative regulation of biological process GO:0048519 304 0.160
morphogenesis of an epithelium GO:0002009 333 0.158
single organism organelle organization GO:1902589 199 0.157
embryonic organ development GO:0048568 381 0.149
determination of left right symmetry GO:0007368 179 0.147
cell surface receptor signaling pathway GO:0007166 325 0.139
g1 s transition of mitotic cell cycle GO:0000082 1 0.126
single organism transport GO:0044765 206 0.124
cellular macromolecule metabolic process GO:0044260 391 0.123
larval development GO:0002164 2 0.121
heart looping GO:0001947 94 0.121
single organism localization GO:1902578 225 0.120
regulation of nitrogen compound metabolic process GO:0051171 251 0.116
regulation of macromolecule metabolic process GO:0060255 317 0.115
skeletal system development GO:0001501 181 0.113
cell part morphogenesis GO:0032990 246 0.112
establishment of localization GO:0051234 244 0.111
response to stress GO:0006950 263 0.111
head development GO:0060322 303 0.109
convergent extension GO:0060026 118 0.099
mitotic cell cycle GO:0000278 64 0.099
purine nucleoside monophosphate catabolic process GO:0009128 4 0.095
cell projection assembly GO:0030031 64 0.091
specification of symmetry GO:0009799 204 0.089
sensory organ development GO:0007423 393 0.084
organic cyclic compound metabolic process GO:1901360 301 0.084
embryonic heart tube development GO:0035050 133 0.082
regulation of biological quality GO:0065008 263 0.080
regulation of multicellular organism growth GO:0040014 4 0.079
sensory perception of chemical stimulus GO:0007606 3 0.079
microtubule based movement GO:0007018 33 0.078
regionalization GO:0003002 274 0.077
regulation of multicellular organismal process GO:0051239 277 0.077
gene expression GO:0010467 252 0.075
ear development GO:0043583 127 0.075
cellular component assembly GO:0022607 170 0.074
camera type eye development GO:0043010 222 0.073
cell projection organization GO:0030030 284 0.072
nucleocytoplasmic transport GO:0006913 4 0.071
establishment of localization in cell GO:0051649 77 0.071
cellular component assembly involved in morphogenesis GO:0010927 107 0.069
cell morphogenesis GO:0000902 289 0.068
muscle cell differentiation GO:0042692 139 0.064
positive regulation of biological process GO:0048518 253 0.064
heart morphogenesis GO:0003007 156 0.062
negative regulation of cellular process GO:0048523 283 0.061
positive regulation of cellular process GO:0048522 201 0.060
cell projection morphogenesis GO:0048858 244 0.060
death GO:0016265 121 0.060
neuron differentiation GO:0030182 353 0.060
transport GO:0006810 220 0.059
organic substance biosynthetic process GO:1901576 289 0.059
photoreceptor cell differentiation GO:0046530 55 0.058
cellular localization GO:0051641 97 0.057
homeostatic process GO:0042592 142 0.057
behavior GO:0007610 74 0.057
multicellular organism growth GO:0035264 4 0.056
positive regulation of camp metabolic process GO:0030816 2 0.056
cell cycle g1 s phase transition GO:0044843 1 0.053
negative regulation of kinase activity GO:0033673 4 0.052
regulation of cellular metabolic process GO:0031323 320 0.052
determination of heart left right asymmetry GO:0061371 117 0.050
negative regulation of response to stimulus GO:0048585 104 0.049
single organism metabolic process GO:0044710 217 0.049
exocrine pancreas development GO:0031017 28 0.049
negative regulation of protein localization to nucleus GO:1900181 2 0.049
definitive hemopoiesis GO:0060216 18 0.047
transmembrane transport GO:0055085 120 0.045
nuclear transport GO:0051169 4 0.044
gland development GO:0048732 143 0.044
ion transmembrane transport GO:0034220 91 0.042
gastrulation GO:0007369 208 0.042
protein targeting to nucleus GO:0044744 3 0.042
feeding behavior GO:0007631 5 0.042
cellular response to extracellular stimulus GO:0031668 2 0.041
digestive tract morphogenesis GO:0048546 231 0.041
maintenance of location GO:0051235 4 0.041
regulation of response to stimulus GO:0048583 269 0.041
retina development in camera type eye GO:0060041 146 0.040
brain development GO:0007420 293 0.040
regulation of establishment of protein localization GO:0070201 4 0.039
cell cycle GO:0007049 93 0.039
cardiocyte differentiation GO:0035051 44 0.039
mitotic cell cycle process GO:1903047 48 0.038
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.038
neuron projection development GO:0031175 180 0.038
single organism cellular localization GO:1902580 46 0.038
regulation of chromosome segregation GO:0051983 1 0.038
cellular response to starvation GO:0009267 1 0.037
heterocycle biosynthetic process GO:0018130 215 0.037
cellular nitrogen compound biosynthetic process GO:0044271 218 0.036
reproduction GO:0000003 40 0.035
cilium organization GO:0044782 71 0.035
negative regulation of dna metabolic process GO:0051053 4 0.035
single organism biosynthetic process GO:0044711 71 0.034
regulation of biosynthetic process GO:0009889 250 0.034
membrane organization GO:0061024 21 0.034
adult behavior GO:0030534 2 0.033
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.033
regulation of response to extracellular stimulus GO:0032104 1 0.033
retina layer formation GO:0010842 24 0.033
central nervous system neuron differentiation GO:0021953 74 0.032
eye development GO:0001654 277 0.032
regulation of protein import into nucleus GO:0042306 2 0.032
olfactory lobe development GO:0021988 4 0.032
cellular component biogenesis GO:0044085 178 0.031
phosphate containing compound metabolic process GO:0006796 108 0.031
developmental programmed cell death GO:0010623 4 0.030
regulation of synaptic plasticity GO:0048167 1 0.030
lateral inhibition GO:0046331 1 0.030
regulation of reproductive process GO:2000241 4 0.030
heterocycle metabolic process GO:0046483 290 0.030
regulation of nucleocytoplasmic transport GO:0046822 2 0.030
cell substrate adhesion GO:0031589 4 0.029
protein metabolic process GO:0019538 183 0.029
cellular response to external stimulus GO:0071496 2 0.028
localization of cell GO:0051674 244 0.028
growth GO:0040007 174 0.028
nucleobase containing compound metabolic process GO:0006139 274 0.028
response to chemical GO:0042221 320 0.028
multi organism process GO:0051704 134 0.028
intracellular transport GO:0046907 32 0.027
aging GO:0007568 2 0.027
axon development GO:0061564 166 0.026
ribonucleoside monophosphate catabolic process GO:0009158 4 0.026
purine ribonucleotide metabolic process GO:0009150 27 0.026
lipid storage GO:0019915 1 0.026
ribose phosphate biosynthetic process GO:0046390 20 0.026
actomyosin structure organization GO:0031032 53 0.026
mesenchyme development GO:0060485 127 0.026
hindbrain development GO:0030902 91 0.025
multicellular organismal homeostasis GO:0048871 29 0.025
regulation of cellular component organization GO:0051128 86 0.025
purine containing compound metabolic process GO:0072521 29 0.025
mitotic g2 m transition checkpoint GO:0044818 3 0.025
regulation of cytoplasmic transport GO:1903649 4 0.025
response to nutrient GO:0007584 3 0.024
protein complex subunit organization GO:0071822 46 0.024
mitotic cell cycle phase transition GO:0044772 9 0.024
protein localization to membrane GO:0072657 9 0.024
blood circulation GO:0008015 87 0.024
intrinsic apoptotic signaling pathway GO:0097193 20 0.024
sensory organ morphogenesis GO:0090596 200 0.024
generation of neurons GO:0048699 385 0.024
cellular protein metabolic process GO:0044267 129 0.024
mrna 3 end processing GO:0031124 2 0.024
regulation of rna biosynthetic process GO:2001141 213 0.024
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.024
tube closure GO:0060606 1 0.024
transcription from rna polymerase ii promoter GO:0006366 80 0.023
modification dependent macromolecule catabolic process GO:0043632 3 0.023
regulation of organ growth GO:0046620 3 0.023
cellular biosynthetic process GO:0044249 286 0.023
left right pattern formation GO:0060972 19 0.023
regulation of binding GO:0051098 3 0.023
g2 dna damage checkpoint GO:0031572 3 0.023
cell differentiation in spinal cord GO:0021515 40 0.023
anterior posterior pattern specification GO:0009952 152 0.023
negative regulation of cellular catabolic process GO:0031330 3 0.023
endocrine process GO:0050886 2 0.023
ribonucleotide metabolic process GO:0009259 27 0.023
biosynthetic process GO:0009058 294 0.022
reciprocal meiotic recombination GO:0007131 1 0.022
regulation of macromolecule biosynthetic process GO:0010556 225 0.022
axon guidance GO:0007411 86 0.022
organophosphate metabolic process GO:0019637 37 0.022
epithelial tube morphogenesis GO:0060562 148 0.022
cytoskeleton organization GO:0007010 96 0.022
negative regulation of protein kinase activity GO:0006469 4 0.022
programmed cell death GO:0012501 119 0.022
neural retina development GO:0003407 49 0.022
meiotic cell cycle process GO:1903046 3 0.022
renal system process involved in regulation of systemic arterial blood pressure GO:0003071 1 0.021
cell migration GO:0016477 237 0.021
regulation of signal transduction GO:0009966 225 0.021
inner ear development GO:0048839 126 0.021
organonitrogen compound metabolic process GO:1901564 74 0.021
regulation of cellular amino acid metabolic process GO:0006521 0 0.021
g protein coupled receptor signaling pathway GO:0007186 74 0.021
cellular response to stress GO:0033554 62 0.021
regulation of protein transport GO:0051223 3 0.021
cellular aromatic compound metabolic process GO:0006725 295 0.021
germ line stem cell division GO:0042078 1 0.020
neuron projection guidance GO:0097485 86 0.020
actin cytoskeleton organization GO:0030036 63 0.020
protein modification process GO:0036211 100 0.020
negative regulation of protein phosphorylation GO:0001933 4 0.020
protein import GO:0017038 3 0.020
transcription dna templated GO:0006351 181 0.020
negative regulation of feeding behavior GO:2000252 2 0.020
enzyme linked receptor protein signaling pathway GO:0007167 106 0.020
cation transmembrane transport GO:0098655 65 0.019
energy reserve metabolic process GO:0006112 2 0.019
axonogenesis GO:0007409 152 0.019
regulation of transcription dna templated GO:0006355 213 0.019
actin filament based process GO:0030029 64 0.019
negative regulation of protein transport GO:0051224 3 0.019
pancreas development GO:0031016 84 0.019
primary neural tube formation GO:0014020 1 0.019
immune system process GO:0002376 241 0.019
establishment of protein localization to organelle GO:0072594 4 0.018
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.018
skeletal muscle tissue development GO:0007519 67 0.018
phosphorus metabolic process GO:0006793 109 0.018
positive regulation of cellular component biogenesis GO:0044089 3 0.018
regulation of neuron differentiation GO:0045664 56 0.018
negative regulation of dna replication GO:0008156 2 0.018
cyclic nucleotide metabolic process GO:0009187 18 0.018
carbohydrate derivative metabolic process GO:1901135 61 0.018
positive regulation of transport GO:0051050 2 0.018
embryo development ending in birth or egg hatching GO:0009792 271 0.018
lateral line system development GO:0048925 76 0.018
negative regulation of intracellular transport GO:0032387 3 0.018
cellular nitrogen compound metabolic process GO:0034641 290 0.017
nitrogen compound metabolic process GO:0006807 319 0.017
protein localization to plasma membrane GO:0072659 1 0.017
ventral spinal cord development GO:0021517 35 0.017
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.017
regulation of purine nucleotide catabolic process GO:0033121 2 0.017
response to external stimulus GO:0009605 264 0.017
growth plate cartilage morphogenesis GO:0003422 1 0.017
rna 3 end processing GO:0031123 2 0.017
regulation of dna replication GO:0006275 3 0.017
positive regulation of cellular amine metabolic process GO:0033240 0 0.017
rna transport GO:0050658 2 0.017
intracellular signal transduction GO:0035556 85 0.017
mitotic dna damage checkpoint GO:0044773 4 0.017
ameboidal type cell migration GO:0001667 143 0.016
cell matrix adhesion GO:0007160 4 0.016
exocrine system development GO:0035272 28 0.016
embryonic digestive tract morphogenesis GO:0048557 3 0.016
nucleoside monophosphate catabolic process GO:0009125 4 0.016
innervation GO:0060384 3 0.016
regulation of cell development GO:0060284 100 0.016
embryonic digestive tract development GO:0048566 4 0.016
production of molecular mediator of immune response GO:0002440 2 0.016
multi organism reproductive process GO:0044703 36 0.016
pigmentation GO:0043473 85 0.016
inorganic ion transmembrane transport GO:0098660 57 0.016
cell cycle g2 m phase transition GO:0044839 4 0.016
circulatory system process GO:0003013 87 0.016
positive regulation of nucleotide biosynthetic process GO:0030810 8 0.016
atp catabolic process GO:0006200 4 0.016
eye morphogenesis GO:0048592 144 0.016
positive regulation of nucleoside metabolic process GO:0045979 1 0.016
regulation of programmed cell death GO:0043067 101 0.016
response to glucocorticoid GO:0051384 1 0.016
single organism nuclear import GO:1902593 3 0.016
reciprocal dna recombination GO:0035825 1 0.015
regulation of developmental process GO:0050793 247 0.015
microtubule based process GO:0007017 60 0.015
synaptic transmission cholinergic GO:0007271 4 0.015
rna biosynthetic process GO:0032774 181 0.015
aromatic compound biosynthetic process GO:0019438 217 0.015
epidermis development GO:0008544 48 0.015
organelle localization GO:0051640 49 0.015
nuclear import GO:0051170 3 0.015
cell cycle process GO:0022402 53 0.015
regulation of circadian rhythm GO:0042752 4 0.015
cyclic purine nucleotide metabolic process GO:0052652 18 0.015
negative regulation of chromosome organization GO:2001251 1 0.015
positive regulation of epithelial cell differentiation GO:0030858 2 0.015
regulation of cellular amine metabolic process GO:0033238 0 0.015
positive regulation of apoptotic signaling pathway GO:2001235 1 0.015
neuron development GO:0048666 262 0.015
anatomical structure homeostasis GO:0060249 36 0.015
regulation of apoptotic process GO:0042981 98 0.015
cell motility GO:0048870 244 0.014
epithelium migration GO:0090132 25 0.014
developmental cell growth GO:0048588 52 0.014
developmental growth GO:0048589 166 0.014
cell death GO:0008219 121 0.014
muscle structure development GO:0061061 196 0.014
regulation of cell shape GO:0008360 1 0.014
nucleobase containing small molecule metabolic process GO:0055086 32 0.014
positive regulation of cytoskeleton organization GO:0051495 3 0.014
regulation of purine nucleotide biosynthetic process GO:1900371 15 0.014
macromolecular complex assembly GO:0065003 35 0.014
aorta development GO:0035904 4 0.014
membrane repolarization GO:0086009 2 0.014
tissue homeostasis GO:0001894 25 0.014
protein localization GO:0008104 40 0.014
rna metabolic process GO:0016070 219 0.014
smooth muscle contraction GO:0006939 2 0.014
multicellular organism reproduction GO:0032504 35 0.014
macromolecule localization GO:0033036 54 0.014
mrna metabolic process GO:0016071 20 0.014
negative regulation of protein kinase b signaling GO:0051898 2 0.013
regulation of localization GO:0032879 104 0.013
monovalent inorganic cation homeostasis GO:0055067 9 0.013
cellular response to nutrient levels GO:0031669 2 0.013
regulation of heart growth GO:0060420 2 0.013
negative regulation of signal transduction GO:0009968 94 0.013
negative regulation of macromolecule metabolic process GO:0010605 76 0.013
cardiac atrium morphogenesis GO:0003209 2 0.013
spinal cord development GO:0021510 46 0.013
nucleic acid metabolic process GO:0090304 244 0.013
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.013
cytokinesis GO:0000910 3 0.013
guanosine containing compound catabolic process GO:1901069 2 0.013
response to endogenous stimulus GO:0009719 83 0.013
ventricular cardiac muscle tissue development GO:0003229 3 0.013
mitochondrion organization GO:0007005 4 0.013
single organism membrane fusion GO:0044801 2 0.013
amide biosynthetic process GO:0043604 1 0.012
somatic muscle development GO:0007525 4 0.012
protein maturation GO:0051604 12 0.012
proteasomal protein catabolic process GO:0010498 2 0.012
ubiquitin dependent protein catabolic process GO:0006511 3 0.012
regulation of establishment of planar polarity GO:0090175 4 0.012
regulation of cell death GO:0010941 103 0.012
sleep GO:0030431 1 0.012
ribose phosphate metabolic process GO:0019693 27 0.012
negative regulation of protein import into nucleus GO:0042308 2 0.012
establishment of organelle localization GO:0051656 45 0.012
cellular response to hypoxia GO:0071456 1 0.012
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.012
fatty acid catabolic process GO:0009062 1 0.012
response to other organism GO:0051707 97 0.012
receptor clustering GO:0043113 7 0.012
response to corticosteroid GO:0031960 1 0.012
positive regulation of protein polymerization GO:0032273 2 0.012
single organism membrane organization GO:0044802 20 0.012
macromolecular complex subunit organization GO:0043933 74 0.012
embryonic heart tube morphogenesis GO:0003143 108 0.012
regulation of epithelial cell proliferation GO:0050678 3 0.012
response to organic cyclic compound GO:0014070 51 0.012
regulation of protein metabolic process GO:0051246 56 0.012
gtp metabolic process GO:0046039 4 0.012
regulation of response to biotic stimulus GO:0002831 2 0.012
regulation of organelle organization GO:0033043 29 0.012
regulation of locomotion GO:0040012 55 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.012
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.012
protein complex localization GO:0031503 1 0.012
regulation of blood pressure GO:0008217 1 0.012
peripheral nervous system neuron development GO:0048935 22 0.012
nucleoside phosphate metabolic process GO:0006753 28 0.012
receptor recycling GO:0001881 4 0.012
nucleobase containing compound biosynthetic process GO:0034654 205 0.012
regulation of endopeptidase activity GO:0052548 23 0.012
regulation of intracellular protein transport GO:0033157 3 0.012
system process GO:0003008 185 0.011
regulation of gtpase activity GO:0043087 2 0.011
regulation of cell substrate adhesion GO:0010810 1 0.011
regulation of microtubule cytoskeleton organization GO:0070507 3 0.011
positive regulation of cyclic nucleotide metabolic process GO:0030801 8 0.011
neural crest cell differentiation GO:0014033 72 0.011
positive regulation of metabolic process GO:0009893 108 0.011
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.011
regulation of cytokine production GO:0001817 3 0.011
positive regulation of endothelial cell proliferation GO:0001938 1 0.011
positive regulation of protein complex assembly GO:0031334 2 0.011
positive regulation of macromolecule metabolic process GO:0010604 93 0.011
locomotion GO:0040011 313 0.011
regeneration GO:0031099 91 0.011
negative regulation of intracellular protein transport GO:0090317 3 0.011
carbohydrate homeostasis GO:0033500 1 0.011
connective tissue development GO:0061448 99 0.011
pericardium morphogenesis GO:0003344 1 0.011
regulation of cellular protein metabolic process GO:0032268 52 0.011
epithelial cell differentiation GO:0030855 116 0.011
ear morphogenesis GO:0042471 64 0.011
phosphorylation GO:0016310 69 0.011
meiotic chromosome segregation GO:0045132 3 0.011
tube formation GO:0035148 25 0.011
regulation of catalytic activity GO:0050790 55 0.011
epithelial cilium movement GO:0003351 15 0.011
nucleotide metabolic process GO:0009117 28 0.011
regulation of membrane potential GO:0042391 23 0.011
cellular macromolecule localization GO:0070727 21 0.011
striated muscle tissue development GO:0014706 110 0.011
embryonic cranial skeleton morphogenesis GO:0048701 90 0.011
camera type eye morphogenesis GO:0048593 108 0.011
developmental growth involved in morphogenesis GO:0060560 86 0.011
muscle cell development GO:0055001 115 0.011
inorganic cation transmembrane transport GO:0098662 50 0.011
cellular macromolecular complex assembly GO:0034622 24 0.011
circadian sleep wake cycle sleep GO:0050802 1 0.011
regulation of endothelial cell proliferation GO:0001936 1 0.010
protein processing GO:0016485 12 0.010
single organism intracellular transport GO:1902582 25 0.010
cell fate commitment GO:0045165 99 0.010
cell cycle phase transition GO:0044770 9 0.010
apoptotic signaling pathway GO:0097190 23 0.010
regulation of cell cycle GO:0051726 52 0.010
chemotaxis GO:0006935 104 0.010
guanosine containing compound metabolic process GO:1901068 4 0.010
regulation of protein targeting GO:1903533 2 0.010
regulation of nucleotide catabolic process GO:0030811 2 0.010
regulation of nucleoside metabolic process GO:0009118 2 0.010
regulation of nucleic acid templated transcription GO:1903506 213 0.010
striated muscle cell differentiation GO:0051146 129 0.010
multicellular organismal metabolic process GO:0044236 2 0.010
cellular response to chemical stimulus GO:0070887 157 0.010
macromolecule biosynthetic process GO:0009059 227 0.010
rna localization GO:0006403 4 0.010
purine ribonucleotide biosynthetic process GO:0009152 20 0.010
establishment of chromosome localization GO:0051303 2 0.010
positive regulation of catabolic process GO:0009896 4 0.010
negative regulation of cytoplasmic transport GO:1903650 2 0.010
dorsal ventral pattern formation GO:0009953 125 0.010

LOC100150924 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.045
inherited metabolic disorder DOID:655 0 0.045
disease of anatomical entity DOID:7 0 0.026
cardiovascular system disease DOID:1287 0 0.022
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
organ system cancer DOID:0050686 0 0.013
myopathy DOID:423 0 0.012
muscular disease DOID:0080000 0 0.012
heart disease DOID:114 0 0.012
cardiomyopathy DOID:0050700 0 0.012
intrinsic cardiomyopathy DOID:0060036 0 0.012
musculoskeletal system disease DOID:17 0 0.012
muscle tissue disease DOID:66 0 0.012
endocrine system disease DOID:28 0 0.011
immune system disease DOID:2914 0 0.011
aplastic anemia DOID:12449 0 0.011
bone marrow disease DOID:4961 0 0.011
anemia DOID:2355 0 0.011
hematopoietic system disease DOID:74 0 0.011
retinal disease DOID:5679 0 0.010
sensory system disease DOID:0050155 0 0.010
eye and adnexa disease DOID:1492 0 0.010
nervous system disease DOID:863 0 0.010
eye disease DOID:5614 0 0.010