Danio rerio

0 known processes

pias4b

protein inhibitor of activated STAT, 4b

(Aliases: zgc:63923,MGC63923,pias4l,fi26h11,wu:fi26h11)

pias4b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of macromolecule metabolic process GO:0060255 317 0.274
regulation of metabolic process GO:0019222 359 0.259
regulation of nitrogen compound metabolic process GO:0051171 251 0.251
nitrogen compound metabolic process GO:0006807 319 0.239
cellular nitrogen compound biosynthetic process GO:0044271 218 0.222
gene expression GO:0010467 252 0.162
regulation of primary metabolic process GO:0080090 311 0.154
nucleic acid metabolic process GO:0090304 244 0.153
cellular nitrogen compound metabolic process GO:0034641 290 0.150
rna metabolic process GO:0016070 219 0.142
cellular macromolecule metabolic process GO:0044260 391 0.120
nucleobase containing compound metabolic process GO:0006139 274 0.114
regulation of transcription dna templated GO:0006355 213 0.113
signal transduction GO:0007165 455 0.103
Zebrafish
regulation of signaling GO:0023051 235 0.099
Zebrafish
regulation of molecular function GO:0065009 70 0.099
aging GO:0007568 2 0.098
larval development GO:0002164 2 0.097
digestive system development GO:0055123 289 0.096
regulation of signal transduction GO:0009966 225 0.094
Zebrafish
embryo development ending in birth or egg hatching GO:0009792 271 0.085
regulation of cellular metabolic process GO:0031323 320 0.084
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.083
heterocycle metabolic process GO:0046483 290 0.080
nucleobase containing compound biosynthetic process GO:0034654 205 0.080
stem cell division GO:0017145 1 0.074
cellular macromolecule biosynthetic process GO:0034645 224 0.071
rna biosynthetic process GO:0032774 181 0.069
regulation of biosynthetic process GO:0009889 250 0.069
negative regulation of cellular process GO:0048523 283 0.068
Zebrafish
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.066
heterocycle biosynthetic process GO:0018130 215 0.064
transcription dna templated GO:0006351 181 0.064
regulation of rna metabolic process GO:0051252 224 0.064
intracellular signal transduction GO:0035556 85 0.060
regulation of gene expression GO:0010468 265 0.060
regionalization GO:0003002 274 0.059
cellular aromatic compound metabolic process GO:0006725 295 0.059
vasculature development GO:0001944 278 0.057
negative regulation of biological process GO:0048519 304 0.057
Zebrafish
regulation of macromolecule biosynthetic process GO:0010556 225 0.056
cellular biosynthetic process GO:0044249 286 0.055
organic cyclic compound biosynthetic process GO:1901362 223 0.054
regulation of binding GO:0051098 3 0.054
organic cyclic compound metabolic process GO:1901360 301 0.052
positive regulation of biological process GO:0048518 253 0.050
negative regulation of cytokine production GO:0001818 1 0.049
Zebrafish
blood vessel development GO:0001568 246 0.049
positive regulation of cellular catabolic process GO:0031331 3 0.047
cell surface receptor signaling pathway GO:0007166 325 0.046
Zebrafish
amine metabolic process GO:0009308 2 0.045
nucleic acid templated transcription GO:0097659 181 0.044
locomotion GO:0040011 313 0.044
oocyte maturation GO:0001556 4 0.043
blood vessel morphogenesis GO:0048514 216 0.043
positive regulation of cell cycle GO:0045787 3 0.043
regulation of cellular biosynthetic process GO:0031326 245 0.042
organonitrogen compound metabolic process GO:1901564 74 0.041
spermatid development GO:0007286 2 0.041
neuron projection development GO:0031175 180 0.041
regulation of nucleic acid templated transcription GO:1903506 213 0.040
hematopoietic or lymphoid organ development GO:0048534 191 0.040
macromolecule biosynthetic process GO:0009059 227 0.040
negative regulation of biosynthetic process GO:0009890 55 0.039
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.039
cellular component biogenesis GO:0044085 178 0.038
neuron differentiation GO:0030182 353 0.038
meiotic nuclear division GO:0007126 4 0.037
hemopoiesis GO:0030097 183 0.037
regulation of circadian rhythm GO:0042752 4 0.035
positive regulation of map kinase activity GO:0043406 3 0.034
maintenance of location GO:0051235 4 0.033
negative regulation of signaling GO:0023057 96 0.033
Zebrafish
cellular component assembly GO:0022607 170 0.032
cellular amine metabolic process GO:0044106 2 0.032
negative regulation of cellular metabolic process GO:0031324 77 0.032
regulation of cell death GO:0010941 103 0.032
response to ketone GO:1901654 1 0.032
cell motility GO:0048870 244 0.031
regulation of developmental process GO:0050793 247 0.031
regulation of multicellular organismal process GO:0051239 277 0.030
Zebrafish
multi organism process GO:0051704 134 0.030
stem cell maintenance GO:0019827 4 0.030
positive regulation of catabolic process GO:0009896 4 0.030
response to topologically incorrect protein GO:0035966 2 0.029
regulation of rna biosynthetic process GO:2001141 213 0.028
regulation of embryonic development GO:0045995 47 0.028
glucose homeostasis GO:0042593 1 0.027
germ line stem cell maintenance GO:0030718 2 0.027
regulation of carbohydrate metabolic process GO:0006109 4 0.027
regulation of cytokine production GO:0001817 3 0.027
Zebrafish
immune system development GO:0002520 191 0.027
sensory organ development GO:0007423 393 0.026
response to stress GO:0006950 263 0.026
Zebrafish
response to vitamin GO:0033273 3 0.026
single organism organelle organization GO:1902589 199 0.026
heart development GO:0007507 313 0.026
apoptotic process GO:0006915 116 0.026
biosynthetic process GO:0009058 294 0.026
development of primary female sexual characteristics GO:0046545 4 0.026
regulation of cell communication GO:0010646 232 0.025
Zebrafish
activation of mapk activity GO:0000187 3 0.025
tube morphogenesis GO:0035239 349 0.025
immune system process GO:0002376 241 0.025
Zebrafish
positive regulation of cytokine production GO:0001819 2 0.024
blood circulation GO:0008015 87 0.024
heart contraction GO:0060047 71 0.024
negative regulation of reproductive process GO:2000242 3 0.024
protein metabolic process GO:0019538 183 0.024
lateral inhibition GO:0046331 1 0.024
regulation of apoptotic process GO:0042981 98 0.024
developmental growth involved in morphogenesis GO:0060560 86 0.024
regulation of reproductive process GO:2000241 4 0.024
neuron development GO:0048666 262 0.023
central nervous system development GO:0007417 387 0.023
cellular response to extracellular stimulus GO:0031668 2 0.023
digestive tract development GO:0048565 265 0.023
gastrulation GO:0007369 208 0.023
transport GO:0006810 220 0.023
regulation of multicellular organism growth GO:0040014 4 0.023
circulatory system process GO:0003013 87 0.022
negative regulation of cellular biosynthetic process GO:0031327 55 0.022
establishment of localization GO:0051234 244 0.022
developmental growth GO:0048589 166 0.021
cellular response to external stimulus GO:0071496 2 0.021
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.021
cell death GO:0008219 121 0.021
guanosine containing compound catabolic process GO:1901069 2 0.021
regulation of bmp signaling pathway GO:0030510 39 0.021
death GO:0016265 121 0.021
digestive tract morphogenesis GO:0048546 231 0.021
regulation of establishment of protein localization GO:0070201 4 0.021
positive regulation of response to stimulus GO:0048584 80 0.020
positive regulation of cellular process GO:0048522 201 0.020
ovarian follicle development GO:0001541 2 0.020
negative regulation of apoptotic process GO:0043066 55 0.020
angiogenesis GO:0001525 158 0.020
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.019
cell part morphogenesis GO:0032990 246 0.019
epidermis development GO:0008544 48 0.019
embryonic organ development GO:0048568 381 0.019
cell maturation GO:0048469 23 0.019
heart process GO:0003015 71 0.019
negative regulation of macromolecule metabolic process GO:0010605 76 0.019
regulation of intracellular signal transduction GO:1902531 57 0.018
cell projection organization GO:0030030 284 0.018
phosphate containing compound metabolic process GO:0006796 108 0.018
localization of cell GO:0051674 244 0.018
positive regulation of transport GO:0051050 2 0.018
generation of neurons GO:0048699 385 0.018
gtp metabolic process GO:0046039 4 0.018
specification of symmetry GO:0009799 204 0.018
regulation of catalytic activity GO:0050790 55 0.018
epithelial cell differentiation GO:0030855 116 0.018
phosphorus metabolic process GO:0006793 109 0.018
regulation of cellular amine metabolic process GO:0033238 0 0.017
macromolecule modification GO:0043412 111 0.017
response to wounding GO:0009611 116 0.017
bmp signaling pathway GO:0030509 52 0.017
cellular carbohydrate metabolic process GO:0044262 4 0.017
positive regulation of protein kinase b signaling GO:0051897 1 0.017
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.017
determination of bilateral symmetry GO:0009855 204 0.016
axonogenesis GO:0007409 152 0.016
gtp catabolic process GO:0006184 2 0.016
cell morphogenesis GO:0000902 289 0.016
organic substance biosynthetic process GO:1901576 289 0.016
regulation of biological quality GO:0065008 263 0.016
regulation of multicellular organismal development GO:2000026 223 0.016
growth GO:0040007 174 0.016
regulation of proteolysis GO:0030162 24 0.016
brain development GO:0007420 293 0.016
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.016
negative regulation of molecular function GO:0044092 23 0.016
single organism metabolic process GO:0044710 217 0.015
cellular component movement GO:0006928 335 0.015
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.015
enzyme linked receptor protein signaling pathway GO:0007167 106 0.015
cell projection morphogenesis GO:0048858 244 0.015
stem cell proliferation GO:0072089 4 0.015
multicellular organism growth GO:0035264 4 0.015
positive regulation of cellular metabolic process GO:0031325 94 0.015
specification of organ identity GO:0010092 2 0.015
regulation of defense response GO:0031347 14 0.015
Zebrafish
regulation of cellular component organization GO:0051128 86 0.015
cell migration involved in gastrulation GO:0042074 79 0.015
cellular response to nutrient levels GO:0031669 2 0.015
transcription from rna polymerase ii promoter GO:0006366 80 0.015
regulation of programmed cell death GO:0043067 101 0.014
dicarboxylic acid metabolic process GO:0043648 1 0.014
regulation of inflammatory response GO:0050727 2 0.014
cell proliferation GO:0008283 80 0.014
ameboidal type cell migration GO:0001667 143 0.014
regulation of immune system process GO:0002682 34 0.014
Zebrafish
cytokinesis GO:0000910 3 0.014
segmentation GO:0035282 97 0.014
collagen metabolic process GO:0032963 2 0.014
macromolecular complex subunit organization GO:0043933 74 0.014
negative regulation of metabolic process GO:0009892 86 0.014
single organism localization GO:1902578 225 0.013
circadian sleep wake cycle process GO:0022410 2 0.013
skin development GO:0043588 54 0.013
head development GO:0060322 303 0.013
lipid storage GO:0019915 1 0.013
female sex differentiation GO:0046660 4 0.013
female gonad development GO:0008585 4 0.013
negative regulation of tor signaling GO:0032007 2 0.013
cellular response to unfolded protein GO:0034620 2 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.013
developmental maturation GO:0021700 34 0.012
regulation of response to cytokine stimulus GO:0060759 3 0.012
Zebrafish
dna alkylation GO:0006305 8 0.012
negative regulation of innate immune response GO:0045824 2 0.012
Zebrafish
protein complex subunit organization GO:0071822 46 0.012
cellular ketone metabolic process GO:0042180 11 0.012
regulation of oocyte development GO:0060281 3 0.012
chordate embryonic development GO:0043009 271 0.012
heart field specification GO:0003128 1 0.012
positive regulation of metabolic process GO:0009893 108 0.012
neuroblast proliferation GO:0007405 2 0.012
cellular protein modification process GO:0006464 100 0.011
regulation of response to stimulus GO:0048583 269 0.011
Zebrafish
negative regulation of cell death GO:0060548 60 0.011
male meiosis GO:0007140 2 0.011
cell migration GO:0016477 237 0.011
positive regulation of macromolecule metabolic process GO:0010604 93 0.011
adult behavior GO:0030534 2 0.011
negative regulation of nuclear division GO:0051784 3 0.011
response to chemical GO:0042221 320 0.011
Zebrafish
energy reserve metabolic process GO:0006112 2 0.011
mitotic cell cycle GO:0000278 64 0.011
nucleoside monophosphate catabolic process GO:0009125 4 0.011
regulation of nucleoside metabolic process GO:0009118 2 0.011
regulation of response to nutrient levels GO:0032107 1 0.011
developmental cell growth GO:0048588 52 0.011
spindle assembly GO:0051225 2 0.011
negative regulation of cytokine mediated signaling pathway GO:0001960 2 0.011
Zebrafish
regulation of phosphate metabolic process GO:0019220 43 0.010
multicellular organism reproduction GO:0032504 35 0.010
protein phosphorylation GO:0006468 47 0.010
positive regulation of immune effector process GO:0002699 3 0.010
post anal tail morphogenesis GO:0036342 19 0.010
positive regulation of signal transduction GO:0009967 56 0.010
regulation of purine nucleotide catabolic process GO:0033121 2 0.010
cell aging GO:0007569 2 0.010
meiotic cell cycle process GO:1903046 3 0.010
response to glucocorticoid GO:0051384 1 0.010
negative regulation of multi organism process GO:0043901 3 0.010
muscle cell development GO:0055001 115 0.010
microtubule organizing center organization GO:0031023 1 0.010
cellular localization GO:0051641 97 0.010

pias4b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.032