Danio rerio

0 known processes

cbx3a

chromobox homolog 3a (HP1 gamma homolog, Drosophila)

(Aliases: zgc:153397,wu:fb61b02,MGC153397,cbx3)

cbx3a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.133
aging GO:0007568 2 0.069
cellular macromolecule metabolic process GO:0044260 391 0.065
Human Mouse Fly
regulation of metabolic process GO:0019222 359 0.057
Human Mouse Fly
nitrogen compound metabolic process GO:0006807 319 0.052
Human Mouse Fly
cellular nitrogen compound metabolic process GO:0034641 290 0.048
Human Mouse Fly
heterocycle metabolic process GO:0046483 290 0.047
Human Mouse Fly
establishment of protein localization to organelle GO:0072594 4 0.045
regulation of gene expression GO:0010468 265 0.044
Human Mouse Fly
organic substance biosynthetic process GO:1901576 289 0.043
Human Mouse Fly
regulation of nitrogen compound metabolic process GO:0051171 251 0.043
Human Mouse Fly
organic cyclic compound metabolic process GO:1901360 301 0.043
Human Mouse Fly
positive regulation of transport GO:0051050 2 0.042
signal transduction GO:0007165 455 0.042
aromatic compound biosynthetic process GO:0019438 217 0.042
Human Mouse Fly
protein import into nucleus GO:0006606 3 0.041
multicellular organism growth GO:0035264 4 0.040
cellular aromatic compound metabolic process GO:0006725 295 0.040
Human Mouse Fly
biosynthetic process GO:0009058 294 0.039
Human Mouse Fly
regulation of multicellular organism growth GO:0040014 4 0.038
nucleic acid metabolic process GO:0090304 244 0.038
Human Mouse Fly
gene expression GO:0010467 252 0.037
Human Mouse Fly
nucleocytoplasmic transport GO:0006913 4 0.037
regulation of cellular metabolic process GO:0031323 320 0.037
Human Mouse Fly
cell surface receptor signaling pathway GO:0007166 325 0.037
regulation of protein transport GO:0051223 3 0.037
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.037
Human Mouse Fly
regulation of rna metabolic process GO:0051252 224 0.037
Human Mouse Fly
regulation of establishment of protein localization GO:0070201 4 0.036
regulation of intracellular protein transport GO:0033157 3 0.034
maintenance of location GO:0051235 4 0.034
cellular biosynthetic process GO:0044249 286 0.034
Human Mouse Fly
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.034
Human Mouse Fly
regulation of macromolecule metabolic process GO:0060255 317 0.034
Human Mouse Fly
protein import GO:0017038 3 0.034
cellular nitrogen compound biosynthetic process GO:0044271 218 0.033
Human Mouse Fly
immune system process GO:0002376 241 0.033
phagocytosis GO:0006909 3 0.033
meiotic nuclear division GO:0007126 4 0.033
response to stress GO:0006950 263 0.033
organelle organization GO:0006996 227 0.032
Fly
regulation of protein localization to nucleus GO:1900180 2 0.032
rna metabolic process GO:0016070 219 0.032
Human Mouse Fly
nuclear transport GO:0051169 4 0.032
regulation of protein targeting GO:1903533 2 0.032
single organism nuclear import GO:1902593 3 0.031
transcription dna templated GO:0006351 181 0.031
Human Mouse Fly
amine metabolic process GO:0009308 2 0.031
regulation of binding GO:0051098 3 0.031
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.031
regulation of meiotic cell cycle GO:0051445 1 0.031
modification dependent macromolecule catabolic process GO:0043632 3 0.030
regulation of primary metabolic process GO:0080090 311 0.030
Human Mouse Fly
regulation of protein import into nucleus GO:0042306 2 0.030
cellular amine metabolic process GO:0044106 2 0.030
macromolecule biosynthetic process GO:0009059 227 0.030
Human Mouse Fly
nucleic acid templated transcription GO:0097659 181 0.030
Human Mouse Fly
protein localization to nucleus GO:0034504 3 0.030
regulation of mrna processing GO:0050684 3 0.029
nuclear import GO:0051170 3 0.029
regulation of nucleocytoplasmic transport GO:0046822 2 0.029
lipid storage GO:0019915 1 0.029
cellular protein catabolic process GO:0044257 4 0.028
cellular component biogenesis GO:0044085 178 0.028
Fly
ubiquitin dependent protein catabolic process GO:0006511 3 0.028
cellular component movement GO:0006928 335 0.028
regulation of biosynthetic process GO:0009889 250 0.027
Human Mouse Fly
protein targeting to nucleus GO:0044744 3 0.027
regulation of cellular biosynthetic process GO:0031326 245 0.027
Human Mouse Fly
organic cyclic compound biosynthetic process GO:1901362 223 0.027
Human Mouse Fly
positive regulation of catabolic process GO:0009896 4 0.027
modification dependent protein catabolic process GO:0019941 3 0.027
protein metabolic process GO:0019538 183 0.027
Fly
positive regulation of biological process GO:0048518 253 0.026
Fly
regulation of cytoplasmic transport GO:1903649 4 0.026
cellular macromolecule biosynthetic process GO:0034645 224 0.026
Human Mouse Fly
cytokinesis GO:0000910 3 0.026
regulation of mrna splicing via spliceosome GO:0048024 3 0.026
locomotion GO:0040011 313 0.026
regulation of cellular amine metabolic process GO:0033238 0 0.025
cellular protein metabolic process GO:0044267 129 0.025
Fly
single organism metabolic process GO:0044710 217 0.025
Fly
generation of neurons GO:0048699 385 0.025
regulation of cellular amino acid metabolic process GO:0006521 0 0.025
heterocycle biosynthetic process GO:0018130 215 0.025
Human Mouse Fly
cell cycle g1 s phase transition GO:0044843 1 0.025
double strand break repair GO:0006302 3 0.025
transport GO:0006810 220 0.024
regulation of protein catabolic process GO:0042176 1 0.024
cellular component morphogenesis GO:0032989 336 0.024
proteasomal protein catabolic process GO:0010498 2 0.024
response to chemical GO:0042221 320 0.024
regulation of transcription dna templated GO:0006355 213 0.024
Human Mouse Fly
nucleobase containing compound metabolic process GO:0006139 274 0.024
Human Mouse Fly
regulation of protein complex assembly GO:0043254 3 0.024
positive regulation of cell cycle GO:0045787 3 0.024
neuron differentiation GO:0030182 353 0.024
negative regulation of protein phosphorylation GO:0001933 4 0.024
establishment of localization GO:0051234 244 0.023
regulation of cytokine production GO:0001817 3 0.023
regulation of nucleic acid templated transcription GO:1903506 213 0.023
Human Mouse Fly
protein acetylation GO:0006473 2 0.023
rna biosynthetic process GO:0032774 181 0.023
Human Mouse Fly
regionalization GO:0003002 274 0.023
central nervous system development GO:0007417 387 0.023
regulation of cell communication GO:0010646 232 0.023
positive regulation of cellular catabolic process GO:0031331 3 0.022
embryo development ending in birth or egg hatching GO:0009792 271 0.022
regulation of macromolecule biosynthetic process GO:0010556 225 0.022
Human Mouse Fly
mitochondrion organization GO:0007005 4 0.022
cellular response to external stimulus GO:0071496 2 0.022
nucleobase containing compound biosynthetic process GO:0034654 205 0.021
Human Mouse Fly
positive regulation of cellular process GO:0048522 201 0.021
Fly
organonitrogen compound metabolic process GO:1901564 74 0.021
regulation of response to stimulus GO:0048583 269 0.021
regulation of cell activation GO:0050865 1 0.021
single organism localization GO:1902578 225 0.021
cell morphogenesis GO:0000902 289 0.021
cell migration GO:0016477 237 0.021
protein acylation GO:0043543 3 0.021
cellular response to nutrient levels GO:0031669 2 0.021
growth GO:0040007 174 0.020
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.020
regulation of biological quality GO:0065008 263 0.020
Fly
rna localization GO:0006403 4 0.020
regulation of protein ubiquitination GO:0031396 3 0.020
transcription from rna polymerase ii promoter GO:0006366 80 0.020
Fly
cellular amino acid metabolic process GO:0006520 7 0.020
g1 s transition of mitotic cell cycle GO:0000082 1 0.020
gtp metabolic process GO:0046039 4 0.020
cellular response to extracellular stimulus GO:0031668 2 0.020
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.020
single organism organelle organization GO:1902589 199 0.020
Fly
cellular component disassembly GO:0022411 1 0.020
response to external stimulus GO:0009605 264 0.020
cell part morphogenesis GO:0032990 246 0.020
organic acid metabolic process GO:0006082 31 0.019
response to organic substance GO:0010033 153 0.019
cell motility GO:0048870 244 0.019
meiotic cell cycle process GO:1903046 3 0.019
cell projection morphogenesis GO:0048858 244 0.019
protein secretion GO:0009306 1 0.019
positive regulation of cellular amine metabolic process GO:0033240 0 0.019
negative regulation of protein kinase activity GO:0006469 4 0.019
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.019
cellular response to starvation GO:0009267 1 0.019
stem cell maintenance GO:0019827 4 0.019
peptidyl lysine acetylation GO:0018394 2 0.019
internal peptidyl lysine acetylation GO:0018393 2 0.019
protein complex disassembly GO:0043241 1 0.019
response to drug GO:0042493 3 0.019
cellular component assembly GO:0022607 170 0.018
Fly
regulation of signaling GO:0023051 235 0.018
cellular ketone metabolic process GO:0042180 11 0.018
positive regulation of cytokine production GO:0001819 2 0.018
regulation of cellular ketone metabolic process GO:0010565 7 0.018
positive regulation of metabolic process GO:0009893 108 0.018
Fly
head development GO:0060322 303 0.018
localization of cell GO:0051674 244 0.018
neuron development GO:0048666 262 0.018
autophagy GO:0006914 4 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.017
positive regulation of cellular component biogenesis GO:0044089 3 0.017
Fly
gtp catabolic process GO:0006184 2 0.017
maturation of ssu rrna GO:0030490 1 0.017
regulation of signal transduction GO:0009966 225 0.017
regulation of multicellular organismal process GO:0051239 277 0.017
translational initiation GO:0006413 3 0.017
response to uv GO:0009411 3 0.017
brain development GO:0007420 293 0.017
vasculature development GO:0001944 278 0.017
female sex differentiation GO:0046660 4 0.017
cell projection organization GO:0030030 284 0.016
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.016
telomere maintenance GO:0000723 1 0.016
Fly
regulation of rna biosynthetic process GO:2001141 213 0.016
Human Mouse Fly
female gonad development GO:0008585 4 0.016
cellular response to organic substance GO:0071310 105 0.016
protein stabilization GO:0050821 2 0.016
macromolecular complex disassembly GO:0032984 1 0.016
oxoacid metabolic process GO:0043436 31 0.016
nuclear export GO:0051168 1 0.016
regulation of reproductive process GO:2000241 4 0.016
internal protein amino acid acetylation GO:0006475 2 0.016
regulation of developmental process GO:0050793 247 0.016
tube morphogenesis GO:0035239 349 0.016
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.016
Fly
adult behavior GO:0030534 2 0.016
cellular protein modification process GO:0006464 100 0.016
Fly
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.016
negative regulation of biological process GO:0048519 304 0.016
Human Mouse Fly
alternative mrna splicing via spliceosome GO:0000380 1 0.015
carboxylic acid metabolic process GO:0019752 22 0.015
positive regulation of stress activated mapk cascade GO:0032874 3 0.015
erk1 and erk2 cascade GO:0070371 4 0.015
single organism transport GO:0044765 206 0.015
ribonucleoside monophosphate catabolic process GO:0009158 4 0.015
leukocyte proliferation GO:0070661 1 0.015
heart development GO:0007507 313 0.015
regulation of reactive oxygen species metabolic process GO:2000377 2 0.015
cellular carbohydrate metabolic process GO:0044262 4 0.015
regulation of purine nucleotide catabolic process GO:0033121 2 0.015
phagocytosis engulfment GO:0006911 1 0.015
regulation of autophagy GO:0010506 3 0.015
cellular response to chemical stimulus GO:0070887 157 0.015
blood vessel development GO:0001568 246 0.015
digestive tract development GO:0048565 265 0.015
centrosome organization GO:0051297 1 0.015
immune system development GO:0002520 191 0.015
guanosine containing compound catabolic process GO:1901069 2 0.015
regulation of nucleotide catabolic process GO:0030811 2 0.015
digestive system development GO:0055123 289 0.015
regulation of nucleoside metabolic process GO:0009118 2 0.015
actin polymerization or depolymerization GO:0008154 2 0.015
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.015
Fly
organelle assembly GO:0070925 110 0.015
tissue remodeling GO:0048771 4 0.014
cytoskeleton dependent cytokinesis GO:0061640 3 0.014
membrane fusion GO:0061025 2 0.014
oocyte anterior posterior axis specification GO:0007314 4 0.014
developmental growth GO:0048589 166 0.014
guanosine containing compound metabolic process GO:1901068 4 0.014
negative regulation of cytokine production GO:0001818 1 0.014
regulation of inflammatory response GO:0050727 2 0.014
sympathetic nervous system development GO:0048485 3 0.014
development of primary female sexual characteristics GO:0046545 4 0.014
single fertilization GO:0007338 3 0.014
cognition GO:0050890 1 0.014
hematopoietic or lymphoid organ development GO:0048534 191 0.014
protein localization to plasma membrane GO:0072659 1 0.014
positive regulation of secretion GO:0051047 1 0.014
activation of mapk activity GO:0000187 3 0.014
response to nutrient GO:0007584 3 0.014
negative regulation of kinase activity GO:0033673 4 0.014
positive regulation of secretion by cell GO:1903532 1 0.014
regulation of gtpase activity GO:0043087 2 0.014
macromolecule modification GO:0043412 111 0.014
Fly
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.014
regulation of cell shape GO:0008360 1 0.014
regulation of multicellular organismal development GO:2000026 223 0.014
small molecule metabolic process GO:0044281 77 0.014
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.014
atp catabolic process GO:0006200 4 0.014
i kappab kinase nf kappab signaling GO:0007249 4 0.014
enzyme linked receptor protein signaling pathway GO:0007167 106 0.014
purine nucleoside monophosphate catabolic process GO:0009128 4 0.014
cellular response to reactive oxygen species GO:0034614 2 0.014
protein polymerization GO:0051258 4 0.014
regulation of cellular protein catabolic process GO:1903362 1 0.014
blood vessel morphogenesis GO:0048514 216 0.013
cellular response to radiation GO:0071478 4 0.013
fertilization GO:0009566 3 0.013
negative regulation of catabolic process GO:0009895 3 0.013
protein dephosphorylation GO:0006470 3 0.013
regulation of transporter activity GO:0032409 2 0.013
positive regulation of cell adhesion GO:0045785 1 0.013
mononuclear cell proliferation GO:0032943 1 0.013
cellular amide metabolic process GO:0043603 4 0.013
multi organism process GO:0051704 134 0.013
actin filament polymerization GO:0030041 2 0.013
embryonic organ development GO:0048568 381 0.013
dna templated transcription elongation GO:0006354 3 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.013
Human Mouse Fly
single organism membrane fusion GO:0044801 2 0.013
positive regulation of cytoskeleton organization GO:0051495 3 0.013
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.013
developmental programmed cell death GO:0010623 4 0.013
mitotic dna integrity checkpoint GO:0044774 4 0.013
extrinsic apoptotic signaling pathway GO:0097191 3 0.013
response to carbohydrate GO:0009743 3 0.013
negative regulation of map kinase activity GO:0043407 2 0.013
stem cell proliferation GO:0072089 4 0.013
muscle structure development GO:0061061 196 0.013
regulation of jun kinase activity GO:0043506 3 0.013
regulation of erk1 and erk2 cascade GO:0070372 4 0.013
regulation of synapse organization GO:0050807 3 0.012
negative regulation of cellular process GO:0048523 283 0.012
Human Mouse Fly
cell morphogenesis involved in differentiation GO:0000904 195 0.012
angiogenesis GO:0001525 158 0.012
meiotic chromosome segregation GO:0045132 3 0.012
morphogenesis of an epithelium GO:0002009 333 0.012
cellular component assembly involved in morphogenesis GO:0010927 107 0.012
post embryonic organ development GO:0048569 4 0.012
neuron projection development GO:0031175 180 0.012
meiosis i GO:0007127 1 0.012
positive regulation of cellular metabolic process GO:0031325 94 0.012
Fly
positive regulation of cell activation GO:0050867 1 0.012
mitotic cell cycle GO:0000278 64 0.012
response to glucose GO:0009749 3 0.012
carbohydrate biosynthetic process GO:0016051 1 0.012
regulation of molecular function GO:0065009 70 0.012
peptide transport GO:0015833 1 0.012
sensory organ development GO:0007423 393 0.012
production of molecular mediator of immune response GO:0002440 2 0.012
cytoplasm organization GO:0007028 4 0.012
positive regulation of translation GO:0045727 1 0.012
anterior posterior pattern specification GO:0009952 152 0.012
eye development GO:0001654 277 0.012
mitotic cytokinesis GO:0000281 3 0.012
spermatid development GO:0007286 2 0.012
sequestering of metal ion GO:0051238 3 0.012
axon development GO:0061564 166 0.012
hemopoiesis GO:0030097 183 0.012
mitotic dna damage checkpoint GO:0044773 4 0.012
telomere organization GO:0032200 1 0.012
Fly
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.012
cellular response to molecule of bacterial origin GO:0071219 3 0.012
cellular response to biotic stimulus GO:0071216 3 0.012
system process GO:0003008 185 0.011
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.011
regulation of neural precursor cell proliferation GO:2000177 3 0.011
negative regulation of metabolic process GO:0009892 86 0.011
Human Mouse Fly
gland development GO:0048732 143 0.011
b cell activation GO:0042113 2 0.011
negative regulation of defense response GO:0031348 2 0.011
regulation of carbohydrate metabolic process GO:0006109 4 0.011
rna transport GO:0050658 2 0.011
negative regulation of protein transport GO:0051224 3 0.011
g2 dna damage checkpoint GO:0031572 3 0.011
membrane invagination GO:0010324 1 0.011
cellular localization GO:0051641 97 0.011
regulation of gtp catabolic process GO:0033124 2 0.011
regulation of organelle assembly GO:1902115 4 0.011
synaptic growth at neuromuscular junction GO:0051124 2 0.011
regulation of production of molecular mediator of immune response GO:0002700 1 0.011
regulation of localization GO:0032879 104 0.011
spermatid differentiation GO:0048515 2 0.011
regulation of growth rate GO:0040009 1 0.011
digestive tract morphogenesis GO:0048546 231 0.011
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.011
cellular response to light stimulus GO:0071482 4 0.011
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.011
establishment of rna localization GO:0051236 3 0.011
negative regulation of cytoplasmic transport GO:1903650 2 0.011
negative regulation of protein complex assembly GO:0031333 1 0.011
regulation of synapse assembly GO:0051963 3 0.011
regulation of muscle contraction GO:0006937 3 0.011
adherens junction organization GO:0034332 4 0.011
homeostatic process GO:0042592 142 0.011
Fly
sequestering of calcium ion GO:0051208 3 0.011
response to topologically incorrect protein GO:0035966 2 0.011
spindle assembly GO:0051225 2 0.011
lymphocyte proliferation GO:0046651 1 0.011
response to hydrogen peroxide GO:0042542 3 0.011
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.011
protein modification process GO:0036211 100 0.011
Fly
negative regulation of intracellular transport GO:0032387 3 0.011
regulation of protein polymerization GO:0032271 2 0.011
positive regulation of protein complex assembly GO:0031334 2 0.011
intracellular mrna localization GO:0008298 1 0.011
negative regulation of mapk cascade GO:0043409 4 0.011
positive regulation of nucleotide catabolic process GO:0030813 1 0.011
regulation of microtubule cytoskeleton organization GO:0070507 3 0.011
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000462 1 0.011
cilium morphogenesis GO:0060271 85 0.011
multi organism cellular process GO:0044764 2 0.011
peptidyl serine modification GO:0018209 2 0.011
phosphorus metabolic process GO:0006793 109 0.011
striated muscle cell development GO:0055002 108 0.011
apoptotic process GO:0006915 116 0.011
Fly
programmed cell death GO:0012501 119 0.011
Fly
positive regulation of map kinase activity GO:0043406 3 0.010
death GO:0016265 121 0.010
Fly
cell death GO:0008219 121 0.010
Fly
intracellular signal transduction GO:0035556 85 0.010
negative regulation of dna metabolic process GO:0051053 4 0.010
negative regulation of nuclear division GO:0051784 3 0.010
positive regulation of gtpase activity GO:0043547 1 0.010
response to monosaccharide GO:0034284 3 0.010
compound eye development GO:0048749 2 0.010
positive regulation of cell division GO:0051781 2 0.010
positive regulation of gtp catabolic process GO:0033126 1 0.010
interspecies interaction between organisms GO:0044419 4 0.010
nucleoside monophosphate catabolic process GO:0009125 4 0.010
startle response GO:0001964 4 0.010
neuron projection morphogenesis GO:0048812 161 0.010
regulation of apoptotic process GO:0042981 98 0.010
Fly
negative regulation of chromosome organization GO:2001251 1 0.010
cell matrix adhesion GO:0007160 4 0.010
regulation of response to biotic stimulus GO:0002831 2 0.010
wound healing GO:0042060 90 0.010
dorsal ventral pattern formation GO:0009953 125 0.010
cellular response to stress GO:0033554 62 0.010
response to endogenous stimulus GO:0009719 83 0.010
rna export from nucleus GO:0006405 1 0.010
negative regulation of multi organism process GO:0043901 3 0.010
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.010

cbx3a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.042
musculoskeletal system disease DOID:17 0 0.020
nervous system disease DOID:863 0 0.019
muscular disease DOID:0080000 0 0.015
muscle tissue disease DOID:66 0 0.015
disease of cellular proliferation DOID:14566 0 0.015
cancer DOID:162 0 0.015
organ system cancer DOID:0050686 0 0.014
myopathy DOID:423 0 0.012