Danio rerio

18 known processes

id3

inhibitor of DNA binding 3

(Aliases: wu:fa56g03,xx:tdsubc_2g3,fa56g03,tdsubc_2g3,ik:tdsubc_2g3)

id3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
stem cell differentiation GO:0048863 117 0.855
gene expression GO:0010467 252 0.761
Human Mouse Fly
signal transduction GO:0007165 455 0.689
chordate embryonic development GO:0043009 271 0.652
digestive tract morphogenesis GO:0048546 231 0.553
organic cyclic compound metabolic process GO:1901360 301 0.546
Human Mouse Rat Fly
regulation of stem cell differentiation GO:2000736 4 0.506
regulation of multicellular organismal development GO:2000026 223 0.461
Zebrafish Mouse
rna biosynthetic process GO:0032774 181 0.442
Human Mouse Fly
cellular nitrogen compound metabolic process GO:0034641 290 0.408
Human Mouse Rat Fly
nucleic acid templated transcription GO:0097659 181 0.398
Human Mouse Fly
programmed cell death GO:0012501 119 0.385
Rat
regulation of cellular metabolic process GO:0031323 320 0.384
Human Mouse Rat Fly
rna metabolic process GO:0016070 219 0.378
Human Mouse Fly
stem cell development GO:0048864 82 0.358
cellular nitrogen compound biosynthetic process GO:0044271 218 0.330
Human Mouse Fly
regulation of rna biosynthetic process GO:2001141 213 0.326
Human Mouse Fly
positive regulation of cellular process GO:0048522 201 0.325
Rat
heterocycle biosynthetic process GO:0018130 215 0.323
Human Mouse Fly
cell fate commitment GO:0045165 99 0.322
Fly
regulation of signal transduction GO:0009966 225 0.318
regulation of biosynthetic process GO:0009889 250 0.295
Human Mouse Rat Fly
heterocycle metabolic process GO:0046483 290 0.294
Human Mouse Rat Fly
cellular biosynthetic process GO:0044249 286 0.284
Human Mouse Rat Fly
mesenchymal cell differentiation GO:0048762 87 0.270
negative regulation of cellular process GO:0048523 283 0.265
Human Zebrafish Mouse Fly
digestive tract development GO:0048565 265 0.264
Fly
transcription from rna polymerase ii promoter GO:0006366 80 0.257
Mouse Fly
cellular component morphogenesis GO:0032989 336 0.257
Fly
cellular macromolecule biosynthetic process GO:0034645 224 0.257
Human Mouse Rat Fly
muscle cell differentiation GO:0042692 139 0.237
Mouse
axon guidance GO:0007411 86 0.235
cell motility GO:0048870 244 0.234
cell proliferation GO:0008283 80 0.234
Fly
regulation of apoptotic process GO:0042981 98 0.234
Rat
skeletal system development GO:0001501 181 0.232
regulation of cell differentiation GO:0045595 142 0.217
Zebrafish Mouse
transcription dna templated GO:0006351 181 0.216
Human Mouse Fly
nucleic acid metabolic process GO:0090304 244 0.214
Human Mouse Rat Fly
embryonic organ morphogenesis GO:0048562 274 0.212
response to stress GO:0006950 263 0.210
Zebrafish Rat
mesenchymal cell development GO:0014031 78 0.208
regulation of macromolecule biosynthetic process GO:0010556 225 0.206
Human Mouse Rat Fly
biosynthetic process GO:0009058 294 0.201
Human Mouse Rat Fly
convergent extension GO:0060026 118 0.192
stem cell maintenance GO:0019827 4 0.190
regulation of nitrogen compound metabolic process GO:0051171 251 0.189
Human Mouse Rat Fly
regulation of transcription dna templated GO:0006355 213 0.188
Human Mouse Fly
macromolecule biosynthetic process GO:0009059 227 0.186
Human Mouse Rat Fly
generation of neurons GO:0048699 385 0.177
death GO:0016265 121 0.176
Rat
pigmentation GO:0043473 85 0.175
regulation of programmed cell death GO:0043067 101 0.175
Rat
nucleobase containing compound metabolic process GO:0006139 274 0.171
Human Mouse Rat Fly
positive regulation of cell cycle GO:0045787 3 0.164
gland development GO:0048732 143 0.160
aromatic compound biosynthetic process GO:0019438 217 0.159
Human Mouse Fly
connective tissue development GO:0061448 99 0.159
regulation of gene expression GO:0010468 265 0.157
Human Mouse Fly
ameboidal type cell migration GO:0001667 143 0.156
regulation of macromolecule metabolic process GO:0060255 317 0.156
Human Mouse Rat Fly
mesenchyme development GO:0060485 127 0.155
intra s dna damage checkpoint GO:0031573 1 0.153
Zebrafish
localization of cell GO:0051674 244 0.146
cellular macromolecule metabolic process GO:0044260 391 0.146
Human Mouse Rat Fly
apoptotic process GO:0006915 116 0.144
Rat
positive regulation of macromolecule metabolic process GO:0010604 93 0.142
head development GO:0060322 303 0.140
Fly
neural crest cell migration GO:0001755 42 0.136
larval development GO:0002164 2 0.135
immune response GO:0006955 28 0.126
regulation of skeletal muscle tissue development GO:0048641 4 0.121
Mouse
cellular aromatic compound metabolic process GO:0006725 295 0.120
Human Mouse Rat Fly
regulation of cellular biosynthetic process GO:0031326 245 0.119
Human Mouse Rat Fly
organic cyclic compound biosynthetic process GO:1901362 223 0.118
Human Mouse Fly
regulation of nucleic acid templated transcription GO:1903506 213 0.118
Human Mouse Fly
amine metabolic process GO:0009308 2 0.114
regulation of metabolic process GO:0019222 359 0.114
Human Mouse Rat Fly
striated muscle cell development GO:0055002 108 0.113
Mouse
regulation of signaling GO:0023051 235 0.110
epithelial cell differentiation GO:0030855 116 0.109
Mouse Fly
embryonic skeletal system development GO:0048706 97 0.107
heart development GO:0007507 313 0.103
Mouse
somatic stem cell maintenance GO:0035019 1 0.102
cellular response to extracellular stimulus GO:0031668 2 0.101
brain development GO:0007420 293 0.101
Fly
regulation of rna metabolic process GO:0051252 224 0.101
Human Mouse Fly
cell morphogenesis GO:0000902 289 0.101
regulation of developmental process GO:0050793 247 0.100
Zebrafish Mouse
regulation of cell communication GO:0010646 232 0.099
positive regulation of metabolic process GO:0009893 108 0.097
negative regulation of cell death GO:0060548 60 0.097
regulation of cell development GO:0060284 100 0.097
Zebrafish Mouse
adult behavior GO:0030534 2 0.097
embryo development ending in birth or egg hatching GO:0009792 271 0.096
Fly
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.096
Human Mouse Rat Fly
gastrulation GO:0007369 208 0.095
cartilage development GO:0051216 96 0.093
embryonic organ development GO:0048568 381 0.091
Mouse
regulation of primary metabolic process GO:0080090 311 0.090
Human Mouse Rat Fly
regionalization GO:0003002 274 0.090
Fly
cell fate specification GO:0001708 68 0.089
vasculature development GO:0001944 278 0.089
hematopoietic or lymphoid organ development GO:0048534 191 0.088
central nervous system development GO:0007417 387 0.086
Mouse Fly
regulation of metal ion transport GO:0010959 4 0.086
regulation of epithelial cell proliferation GO:0050678 3 0.086
neuron differentiation GO:0030182 353 0.085
positive regulation of cellular metabolic process GO:0031325 94 0.085
collagen metabolic process GO:0032963 2 0.085
tube morphogenesis GO:0035239 349 0.083
protein modification process GO:0036211 100 0.083
intracellular signal transduction GO:0035556 85 0.083
regulation of cell proliferation GO:0042127 37 0.081
endoderm development GO:0007492 49 0.080
neuron projection guidance GO:0097485 86 0.079
response to oxygen levels GO:0070482 25 0.078
neural crest cell development GO:0014032 62 0.077
nucleobase containing compound biosynthetic process GO:0034654 205 0.077
Human Mouse Fly
epithelial to mesenchymal transition GO:0001837 21 0.076
positive regulation of molecular function GO:0044093 33 0.076
forebrain development GO:0030900 96 0.073
digestive system development GO:0055123 289 0.073
Fly
regulation of cell death GO:0010941 103 0.072
Rat
germ line stem cell maintenance GO:0030718 2 0.072
positive regulation of cellular protein metabolic process GO:0032270 22 0.069
cell migration GO:0016477 237 0.069
axon ensheathment in central nervous system GO:0032291 2 0.067
axon development GO:0061564 166 0.067
positive regulation of cellular catabolic process GO:0031331 3 0.067
negative regulation of kinase activity GO:0033673 4 0.066
positive regulation of catalytic activity GO:0043085 25 0.066
cellular protein modification process GO:0006464 100 0.065
regulation of organ growth GO:0046620 3 0.064
cellular response to chemical stimulus GO:0070887 157 0.063
apoptotic signaling pathway GO:0097190 23 0.063
establishment of protein localization to organelle GO:0072594 4 0.062
dorsal ventral pattern formation GO:0009953 125 0.062
regulation of catenin import into nucleus GO:0035412 2 0.062
sensory organ development GO:0007423 393 0.061
Fly
regulation of anatomical structure morphogenesis GO:0022603 130 0.060
muscle tissue development GO:0060537 110 0.059
Mouse
positive regulation of biosynthetic process GO:0009891 68 0.059
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.058
regulation of cytoplasmic transport GO:1903649 4 0.058
multi organism process GO:0051704 134 0.057
Fly
cellular amino acid metabolic process GO:0006520 7 0.057
ear morphogenesis GO:0042471 64 0.056
cellular amine metabolic process GO:0044106 2 0.055
cellular component biogenesis GO:0044085 178 0.055
immune system development GO:0002520 191 0.055
inner ear development GO:0048839 126 0.054
negative regulation of protein kinase activity GO:0006469 4 0.054
morphogenesis of an epithelium GO:0002009 333 0.054
Fly
lateral inhibition GO:0046331 1 0.054
Fly
regulation of response to stimulus GO:0048583 269 0.054
peripheral nervous system development GO:0007422 55 0.053
Fly
cranial ganglion development GO:0061550 3 0.053
determination of bilateral symmetry GO:0009855 204 0.053
chemotaxis GO:0006935 104 0.052
exocrine system development GO:0035272 28 0.051
negative regulation of cell differentiation GO:0045596 46 0.051
Mouse
nitrogen compound metabolic process GO:0006807 319 0.051
Human Mouse Rat Fly
regulation of biological quality GO:0065008 263 0.050
positive regulation of catabolic process GO:0009896 4 0.050
single organism organelle organization GO:1902589 199 0.049
single organism metabolic process GO:0044710 217 0.049
protein import into nucleus GO:0006606 3 0.049
positive regulation of gene expression GO:0010628 71 0.048
mitotic cell cycle embryonic GO:0045448 2 0.048
neural crest cell differentiation GO:0014033 72 0.048
regulation of epidermis development GO:0045682 2 0.048
keratinocyte differentiation GO:0030216 0 0.048
positive regulation of rna biosynthetic process GO:1902680 57 0.048
single organism nuclear import GO:1902593 3 0.047
response to abiotic stimulus GO:0009628 122 0.047
immune system process GO:0002376 241 0.046
cell cycle g1 s phase transition GO:0044843 1 0.046
cellular component movement GO:0006928 335 0.046
taxis GO:0042330 109 0.046
determination of left right symmetry GO:0007368 179 0.045
protein localization to nucleus GO:0034504 3 0.045
primary neural tube formation GO:0014020 1 0.044
regulation of binding GO:0051098 3 0.044
Fly
lipid storage GO:0019915 1 0.043
locomotion GO:0040011 313 0.043
Fly
neuron projection development GO:0031175 180 0.043
small gtpase mediated signal transduction GO:0007264 8 0.042
protein targeting to nucleus GO:0044744 3 0.042
protein import GO:0017038 3 0.042
regulation of cellular ketone metabolic process GO:0010565 7 0.041
positive regulation of nucleic acid templated transcription GO:1903508 57 0.041
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.041
Human Mouse Rat Fly
sensory organ morphogenesis GO:0090596 200 0.040
Fly
organelle organization GO:0006996 227 0.040
carboxylic acid metabolic process GO:0019752 22 0.039
regulation of cellular amino acid metabolic process GO:0006521 0 0.039
endothelium development GO:0003158 25 0.039
negative regulation of protein phosphorylation GO:0001933 4 0.038
camera type eye development GO:0043010 222 0.038
aging GO:0007568 2 0.038
muscle cell development GO:0055001 115 0.038
Mouse
embryonic skeletal system morphogenesis GO:0048704 93 0.038
skeletal system morphogenesis GO:0048705 102 0.038
cellular ketone metabolic process GO:0042180 11 0.037
epithelial cell development GO:0002064 42 0.036
Fly
regulation of reproductive process GO:2000241 4 0.036
regulation of catalytic activity GO:0050790 55 0.036
synaptic growth at neuromuscular junction GO:0051124 2 0.036
cell death GO:0008219 121 0.036
Rat
regulation of multicellular organismal process GO:0051239 277 0.036
Zebrafish Mouse
cytoskeleton organization GO:0007010 96 0.035
regulation of epithelial to mesenchymal transition GO:0010717 3 0.035
cellular response to external stimulus GO:0071496 2 0.035
nuclear transport GO:0051169 4 0.034
cell cycle GO:0007049 93 0.034
Zebrafish Rat
actin filament based process GO:0030029 64 0.034
response to decreased oxygen levels GO:0036293 25 0.034
negative regulation of programmed cell death GO:0043069 58 0.033
oxoacid metabolic process GO:0043436 31 0.033
cellular response to stress GO:0033554 62 0.033
Zebrafish
organic substance biosynthetic process GO:1901576 289 0.032
Human Mouse Rat Fly
neuron development GO:0048666 262 0.032
regulation of tyrosine phosphorylation of stat protein GO:0042509 1 0.032
positive regulation of map kinase activity GO:0043406 3 0.032
embryonic viscerocranium morphogenesis GO:0048703 52 0.032
skeletal muscle fiber development GO:0048741 35 0.032
Mouse
behavior GO:0007610 74 0.032
Fly
ear development GO:0043583 127 0.031
regulation of cell activation GO:0050865 1 0.031
neural crest formation GO:0014029 14 0.031
radial glial cell differentiation GO:0060019 2 0.031
epidermal cell fate specification GO:0009957 4 0.030
wound healing GO:0042060 90 0.030
actin cytoskeleton organization GO:0030036 63 0.030
cellular protein catabolic process GO:0044257 4 0.030
positive regulation of cellular biosynthetic process GO:0031328 68 0.030
b cell activation GO:0042113 2 0.029
homeostatic process GO:0042592 142 0.029
response to lipid GO:0033993 60 0.029
response to organic substance GO:0010033 153 0.029
protein metabolic process GO:0019538 183 0.029
cellular component assembly GO:0022607 170 0.029
regulation of embryonic development GO:0045995 47 0.029
multicellular organismal macromolecule metabolic process GO:0044259 2 0.029
g1 s transition of mitotic cell cycle GO:0000082 1 0.029
cellular component assembly involved in morphogenesis GO:0010927 107 0.029
Fly
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.028
negative regulation of biological process GO:0048519 304 0.028
Human Zebrafish Mouse Fly
response to wounding GO:0009611 116 0.028
Rat
response to hypoxia GO:0001666 25 0.028
positive regulation of biological process GO:0048518 253 0.028
Rat
cellular protein metabolic process GO:0044267 129 0.027
regulation of protein metabolic process GO:0051246 56 0.027
nuclear import GO:0051170 3 0.027
epithelial tube morphogenesis GO:0060562 148 0.027
regulation of cellular amine metabolic process GO:0033238 0 0.027
maintenance of location GO:0051235 4 0.026
central nervous system myelination GO:0022010 2 0.026
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.026
Human Mouse Fly
organic acid metabolic process GO:0006082 31 0.026
hatching GO:0035188 4 0.026
cellular response to oxygen levels GO:0071453 1 0.026
blood vessel morphogenesis GO:0048514 216 0.026
hemopoiesis GO:0030097 183 0.026
proteasomal protein catabolic process GO:0010498 2 0.025
enzyme linked receptor protein signaling pathway GO:0007167 106 0.025
macromolecule modification GO:0043412 111 0.025
axonogenesis GO:0007409 152 0.025
estrogen metabolic process GO:0008210 2 0.025
positive regulation of leukocyte differentiation GO:1902107 1 0.025
transmission of nerve impulse GO:0019226 19 0.025
ectodermal placode formation GO:0060788 26 0.025
regulation of protein import into nucleus GO:0042306 2 0.025
cell migration involved in gastrulation GO:0042074 79 0.025
inner ear morphogenesis GO:0042472 63 0.025
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.024
positive regulation of epithelial cell differentiation GO:0030858 2 0.024
blood vessel development GO:0001568 246 0.024
regulation of ectodermal cell fate specification GO:0042665 2 0.024
alcohol biosynthetic process GO:0046165 2 0.024
b cell differentiation GO:0030183 1 0.024
epithelial cell migration GO:0010631 25 0.024
guanosine containing compound metabolic process GO:1901068 4 0.023
extrinsic apoptotic signaling pathway GO:0097191 3 0.023
organism emergence from protective structure GO:0071684 4 0.023
regulation of phosphorus metabolic process GO:0051174 43 0.023
neural tube development GO:0021915 62 0.023
macromolecular complex subunit organization GO:0043933 74 0.022
positive regulation of cell differentiation GO:0045597 30 0.022
regulation of canonical wnt signaling pathway GO:0060828 34 0.022
diencephalon development GO:0021536 58 0.022
epidermal cell differentiation GO:0009913 36 0.022
cell morphogenesis involved in differentiation GO:0000904 195 0.022
mitochondrion organization GO:0007005 4 0.022
response to chemical GO:0042221 320 0.022
muscle structure development GO:0061061 196 0.022
Mouse
endothelial cell differentiation GO:0045446 20 0.021
nucleocytoplasmic transport GO:0006913 4 0.021
response to uv GO:0009411 3 0.021
regulation of gastrulation GO:0010470 24 0.021
negative regulation of cytoplasmic transport GO:1903650 2 0.021
regulation of molecular function GO:0065009 70 0.021
Human Fly
embryonic cranial skeleton morphogenesis GO:0048701 90 0.021
neural precursor cell proliferation GO:0061351 20 0.021
bmp signaling pathway GO:0030509 52 0.021
regulation of kinase activity GO:0043549 15 0.020
regulation of bmp signaling pathway GO:0030510 39 0.020
cellular response to retinoic acid GO:0071300 1 0.020
mesoderm development GO:0007498 88 0.020
organelle assembly GO:0070925 110 0.020
endocrine system development GO:0035270 65 0.019
hindbrain development GO:0030902 91 0.019
positive regulation of transport GO:0051050 2 0.019
ubiquitin dependent protein catabolic process GO:0006511 3 0.019
regulation of response to nutrient levels GO:0032107 1 0.019
regulation of skeletal muscle fiber development GO:0048742 2 0.019
Mouse
negative regulation of cellular metabolic process GO:0031324 77 0.019
Human Mouse Fly
pancreas development GO:0031016 84 0.019
mitotic cell cycle process GO:1903047 48 0.019
Zebrafish
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.019
negative regulation of cell migration GO:0030336 17 0.019
hepaticobiliary system development GO:0061008 98 0.019
negative regulation of epithelial cell proliferation GO:0050680 1 0.019
morphogenesis of an epithelial sheet GO:0002011 49 0.019
bone morphogenesis GO:0060349 11 0.019
cell aging GO:0007569 2 0.019
phosphate containing compound metabolic process GO:0006796 108 0.019
regulation of protein phosphorylation GO:0001932 18 0.019
response to radiation GO:0009314 51 0.019
response to oxygen containing compound GO:1901700 55 0.018
response to corticosteroid GO:0031960 1 0.018
regulation of rho protein signal transduction GO:0035023 2 0.018
neuroblast differentiation GO:0014016 1 0.018
regulation of purine nucleotide catabolic process GO:0033121 2 0.018
regulation of nervous system development GO:0051960 90 0.018
Zebrafish
positive regulation of transcription dna templated GO:0045893 57 0.018
regulation of neuron differentiation GO:0045664 56 0.018
Zebrafish
negative regulation of gliogenesis GO:0014014 1 0.018
stem cell division GO:0017145 1 0.018
positive regulation of cellular component biogenesis GO:0044089 3 0.018
positive regulation of cell proliferation GO:0008284 15 0.018
dna metabolic process GO:0006259 27 0.018
Rat
negative regulation of signaling GO:0023057 96 0.017
mononuclear cell proliferation GO:0032943 1 0.017
cell cell signaling involved in cell fate commitment GO:0045168 12 0.017
Fly
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.017
Human
hatching gland development GO:0048785 3 0.017
regulation of nucleoside metabolic process GO:0009118 2 0.017
positive regulation of cyclin dependent protein serine threonine kinase activity GO:0045737 1 0.017
meiotic nuclear division GO:0007126 4 0.017
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.017
phosphorylation GO:0016310 69 0.017
regulation of intracellular signal transduction GO:1902531 57 0.017
positive regulation of multi organism process GO:0043902 3 0.017
regulation of blood vessel size GO:0050880 2 0.017
myotube cell development GO:0014904 35 0.016
Mouse
specification of symmetry GO:0009799 204 0.016
ras protein signal transduction GO:0007265 7 0.016
phenol containing compound biosynthetic process GO:0046189 4 0.016
regulation of ion transport GO:0043269 22 0.016
cell substrate adhesion GO:0031589 4 0.016
female sex differentiation GO:0046660 4 0.016
positive regulation of nucleoside metabolic process GO:0045979 1 0.016
neuroblast proliferation GO:0007405 2 0.016
single organism localization GO:1902578 225 0.016
regulation of protein localization to nucleus GO:1900180 2 0.016
cell adhesion GO:0007155 40 0.016
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.016
regulation of oligodendrocyte differentiation GO:0048713 1 0.016
regulation of myotube differentiation GO:0010830 2 0.015
Mouse
angiogenesis GO:0001525 158 0.015
regulation of nucleotide catabolic process GO:0030811 2 0.015
multi organism reproductive process GO:0044703 36 0.015
Fly
exocrine pancreas development GO:0031017 28 0.015
alpha amino acid metabolic process GO:1901605 3 0.015
regulation of transferase activity GO:0051338 16 0.015
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.015
catechol containing compound biosynthetic process GO:0009713 2 0.015
regulation of cellular protein metabolic process GO:0032268 52 0.015
liver development GO:0001889 96 0.015
entrainment of circadian clock GO:0009649 2 0.015
lymphocyte proliferation GO:0046651 1 0.015
regulation of cell cycle process GO:0010564 20 0.015
Zebrafish
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.015
endothelial cell fate commitment GO:0060839 3 0.015
small molecule metabolic process GO:0044281 77 0.015
negative regulation of blood vessel endothelial cell migration GO:0043537 1 0.015
regulation of calcium ion transport GO:0051924 2 0.015
positive regulation of cell communication GO:0010647 56 0.015
response to external stimulus GO:0009605 264 0.015
Fly
cell activation GO:0001775 16 0.015
entrainment of circadian clock by photoperiod GO:0043153 1 0.015
sex determination GO:0007530 1 0.015
Fly
left right pattern formation GO:0060972 19 0.014
neural crest cell fate specification GO:0014036 5 0.014
somite development GO:0061053 96 0.014
tube closure GO:0060606 1 0.014
anterior posterior pattern specification GO:0009952 152 0.014
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.014
response to carbohydrate GO:0009743 3 0.014
gtp metabolic process GO:0046039 4 0.014
negative regulation of intracellular transport GO:0032387 3 0.014
post embryonic organ development GO:0048569 4 0.014
Fly
negative regulation of apoptotic process GO:0043066 55 0.014
positive regulation of notch signaling pathway GO:0045747 3 0.014
ectodermal cell fate specification GO:0001715 2 0.014
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.014
Human Mouse Fly
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.014
positive regulation of apoptotic signaling pathway GO:2001235 1 0.014
dna biosynthetic process GO:0071897 3 0.014
negative regulation of gene expression GO:0010629 65 0.014
Human Mouse Fly
proximal distal pattern formation GO:0009954 1 0.014
regulation of ectoderm development GO:2000383 2 0.014
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.014
skeletal muscle tissue development GO:0007519 67 0.014
Mouse
determination of ventral identity GO:0048264 21 0.014
regulation of cytokine production GO:0001817 3 0.013
negative regulation of intracellular protein transport GO:0090317 3 0.013
positive regulation of signaling GO:0023056 56 0.013
notch signaling pathway GO:0007219 35 0.013
negative regulation of epithelial cell differentiation GO:0030857 2 0.013
circulatory system process GO:0003013 87 0.013
lens morphogenesis in camera type eye GO:0002089 7 0.013
cell maturation GO:0048469 23 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.013
Mouse Fly
regulation of actin filament based process GO:0032970 9 0.013
female gonad development GO:0008585 4 0.013
intrinsic apoptotic signaling pathway GO:0097193 20 0.013
positive regulation of nucleotide catabolic process GO:0030813 1 0.013
embryonic heart tube development GO:0035050 133 0.013
neuron projection morphogenesis GO:0048812 161 0.013
response to oxidative stress GO:0006979 11 0.013
actomyosin structure organization GO:0031032 53 0.013
protein stabilization GO:0050821 2 0.013
retina development in camera type eye GO:0060041 146 0.013
regulation of transcription from rna polymerase iii promoter GO:0006359 1 0.013
transcription from rna polymerase iii promoter GO:0006383 1 0.013
paraxial mesoderm development GO:0048339 8 0.013
regulation of tube size GO:0035150 2 0.013
peripheral nervous system neuron axonogenesis GO:0048936 13 0.013
cellular amino acid biosynthetic process GO:0008652 2 0.013
positive regulation of multicellular organismal process GO:0051240 52 0.013
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.013
positive regulation of immune effector process GO:0002699 3 0.012
neural tube patterning GO:0021532 33 0.012
glial cell migration GO:0008347 3 0.012
nerve development GO:0021675 45 0.012
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.012
meiotic cell cycle process GO:1903046 3 0.012
endothelial cell development GO:0001885 12 0.012
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.012
tissue regeneration GO:0042246 74 0.012
negative regulation of metabolic process GO:0009892 86 0.012
Human Mouse Fly
spermatid differentiation GO:0048515 2 0.012
Fly
regulation of phosphate metabolic process GO:0019220 43 0.012
tyrosine phosphorylation of stat protein GO:0007260 1 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.012
negative regulation of dna replication GO:0008156 2 0.012
cellular response to radiation GO:0071478 4 0.012
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.012
regulation of protein targeting GO:1903533 2 0.012
establishment of localization GO:0051234 244 0.012
epiboly GO:0090504 41 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.012
Human Mouse Fly
negative regulation of protein transport GO:0051224 3 0.012
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.012
reproduction GO:0000003 40 0.012
Fly
eye development GO:0001654 277 0.012
Fly
t cell differentiation GO:0030217 6 0.012
pigment cell differentiation GO:0050931 38 0.012
positive regulation of cellular amine metabolic process GO:0033240 0 0.012
regulation of establishment of protein localization GO:0070201 4 0.012
skeletal muscle organ development GO:0060538 78 0.012
Mouse
cell part morphogenesis GO:0032990 246 0.012
er nucleus signaling pathway GO:0006984 2 0.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.011
guanosine containing compound catabolic process GO:1901069 2 0.011
gabaergic neuron differentiation GO:0097154 2 0.011
developmental pigmentation GO:0048066 48 0.011
regulation of neural precursor cell proliferation GO:2000177 3 0.011
cellular response to decreased oxygen levels GO:0036294 1 0.011
methylation GO:0032259 22 0.011
respiratory system development GO:0060541 5 0.011
cellular response to nutrient levels GO:0031669 2 0.011
response to nutrient GO:0007584 3 0.011
catenin import into nucleus GO:0035411 2 0.011
leukocyte activation GO:0045321 12 0.011
foregut morphogenesis GO:0007440 4 0.011
response to metal ion GO:0010038 34 0.011
cellular localization GO:0051641 97 0.011

id3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.033
cancer DOID:162 0 0.021
disease of cellular proliferation DOID:14566 0 0.021
organ system cancer DOID:0050686 0 0.011