Danio rerio

0 known processes

rdh10b

retinol dehydrogenase 10b

(Aliases: cb804,rdh10)

rdh10b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of metabolic process GO:0009893 108 0.196
small molecule metabolic process GO:0044281 77 0.196
Human Mouse Rat
single organism metabolic process GO:0044710 217 0.191
Human Mouse Rat
cellular protein catabolic process GO:0044257 4 0.182
larval development GO:0002164 2 0.157
digestive tract morphogenesis GO:0048546 231 0.142
response to stress GO:0006950 263 0.141
Worm
biosynthetic process GO:0009058 294 0.121
Mouse
regulation of metabolic process GO:0019222 359 0.120
cellular aromatic compound metabolic process GO:0006725 295 0.112
regulation of molecular function GO:0065009 70 0.100
nitrogen compound metabolic process GO:0006807 319 0.098
regulation of biological quality GO:0065008 263 0.092
Human Mouse Rat
cellular macromolecule metabolic process GO:0044260 391 0.087
regulation of cellular metabolic process GO:0031323 320 0.084
heterocycle metabolic process GO:0046483 290 0.071
response to external stimulus GO:0009605 264 0.071
inorganic ion transmembrane transport GO:0098660 57 0.069
organic cyclic compound metabolic process GO:1901360 301 0.065
regulation of blood vessel size GO:0050880 2 0.065
phosphorus metabolic process GO:0006793 109 0.061
regulation of primary metabolic process GO:0080090 311 0.061
regulation of gene expression GO:0010468 265 0.059
nucleobase containing compound metabolic process GO:0006139 274 0.058
phosphate containing compound metabolic process GO:0006796 108 0.056
homeostatic process GO:0042592 142 0.055
regulation of nitrogen compound metabolic process GO:0051171 251 0.054
positive regulation of molecular function GO:0044093 33 0.054
aging GO:0007568 2 0.053
heart development GO:0007507 313 0.051
cell growth GO:0016049 57 0.051
cellular nitrogen compound metabolic process GO:0034641 290 0.049
tube morphogenesis GO:0035239 349 0.049
Mouse
positive regulation of biological process GO:0048518 253 0.049
regulation of catalytic activity GO:0050790 55 0.049
regulation of macromolecule metabolic process GO:0060255 317 0.048
gastrulation GO:0007369 208 0.047
carboxylic acid metabolic process GO:0019752 22 0.047
Mouse
generation of neurons GO:0048699 385 0.046
digestive tract development GO:0048565 265 0.046
guanosine containing compound catabolic process GO:1901069 2 0.045
cell projection morphogenesis GO:0048858 244 0.044
embryonic organ morphogenesis GO:0048562 274 0.043
Mouse
embryo development ending in birth or egg hatching GO:0009792 271 0.043
Mouse Worm
multicellular organism growth GO:0035264 4 0.043
gene expression GO:0010467 252 0.042
cell morphogenesis GO:0000902 289 0.041
cell part morphogenesis GO:0032990 246 0.040
guanosine containing compound metabolic process GO:1901068 4 0.040
positive regulation of transport GO:0051050 2 0.040
regulation of nucleic acid templated transcription GO:1903506 213 0.039
neuron development GO:0048666 262 0.039
nuclear transport GO:0051169 4 0.039
regulation of signal transduction GO:0009966 225 0.038
Zebrafish
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.037
negative regulation of biological process GO:0048519 304 0.037
regulation of neurogenesis GO:0050767 87 0.036
negative regulation of cellular catabolic process GO:0031330 3 0.036
positive regulation of cellular catabolic process GO:0031331 3 0.036
rna metabolic process GO:0016070 219 0.036
bicarbonate transport GO:0015701 4 0.036
intracellular signal transduction GO:0035556 85 0.036
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.035
organonitrogen compound metabolic process GO:1901564 74 0.035
regulation of cytokine production GO:0001817 3 0.034
gtp catabolic process GO:0006184 2 0.034
negative regulation of catabolic process GO:0009895 3 0.034
positive regulation of catabolic process GO:0009896 4 0.033
negative regulation of cellular process GO:0048523 283 0.033
regulation of dna replication GO:0006275 3 0.033
positive regulation of secretion by cell GO:1903532 1 0.033
negative regulation of mitosis GO:0045839 3 0.032
establishment of localization in cell GO:0051649 77 0.032
cell cycle g1 s phase transition GO:0044843 1 0.032
positive regulation of macromolecule metabolic process GO:0010604 93 0.032
regulation of signaling GO:0023051 235 0.031
Zebrafish
g1 s transition of mitotic cell cycle GO:0000082 1 0.031
stem cell fate commitment GO:0048865 1 0.031
response to drug GO:0042493 3 0.031
cellular response to starvation GO:0009267 1 0.031
transport GO:0006810 220 0.031
cellular protein modification process GO:0006464 100 0.030
system process GO:0003008 185 0.030
Human
autophagy GO:0006914 4 0.030
extrinsic apoptotic signaling pathway GO:0097191 3 0.030
regulation of response to stimulus GO:0048583 269 0.030
Zebrafish
negative regulation of epithelial cell proliferation GO:0050680 1 0.030
ubiquitin dependent protein catabolic process GO:0006511 3 0.029
digestive system development GO:0055123 289 0.029
regulation of macromolecule biosynthetic process GO:0010556 225 0.029
single organism organelle organization GO:1902589 199 0.029
neuron differentiation GO:0030182 353 0.029
regulation of cell development GO:0060284 100 0.029
response to chemical GO:0042221 320 0.028
cellular component morphogenesis GO:0032989 336 0.028
immune system development GO:0002520 191 0.028
protein stabilization GO:0050821 2 0.027
multi organism process GO:0051704 134 0.027
cellular amino acid metabolic process GO:0006520 7 0.027
regulation of reproductive process GO:2000241 4 0.027
negative regulation of response to stimulus GO:0048585 104 0.027
response to carbohydrate GO:0009743 3 0.027
regulation of autophagy GO:0010506 3 0.027
regulation of cellular biosynthetic process GO:0031326 245 0.026
death GO:0016265 121 0.026
protein modification process GO:0036211 100 0.026
growth GO:0040007 174 0.026
Mouse
regulation of epithelial cell proliferation GO:0050678 3 0.026
negative regulation of signaling GO:0023057 96 0.025
regulation of skeletal muscle tissue development GO:0048641 4 0.025
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.025
mitotic dna damage checkpoint GO:0044773 4 0.025
response to corticosteroid GO:0031960 1 0.025
regulation of cellular amine metabolic process GO:0033238 0 0.025
developmental growth involved in morphogenesis GO:0060560 86 0.025
Mouse
ribonucleoside monophosphate catabolic process GO:0009158 4 0.025
single organism biosynthetic process GO:0044711 71 0.025
Mouse
response to glucocorticoid GO:0051384 1 0.025
regulation of phosphorus metabolic process GO:0051174 43 0.024
nucleocytoplasmic transport GO:0006913 4 0.024
regulation of protein catabolic process GO:0042176 1 0.024
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.024
regulation of protein import into nucleus GO:0042306 2 0.024
cell projection organization GO:0030030 284 0.024
regulation of gtp catabolic process GO:0033124 2 0.024
gland development GO:0048732 143 0.024
ameboidal type cell migration GO:0001667 143 0.024
cell proliferation GO:0008283 80 0.024
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.023
embryonic heart tube morphogenesis GO:0003143 108 0.023
regulation of response to nutrient levels GO:0032107 1 0.023
response to hexose GO:0009746 3 0.023
cell fate specification GO:0001708 68 0.023
regulation of cellular component organization GO:0051128 86 0.023
regulation of anatomical structure morphogenesis GO:0022603 130 0.023
nucleotide metabolic process GO:0009117 28 0.023
hormone transport GO:0009914 2 0.023
cellular amine metabolic process GO:0044106 2 0.022
response to biotic stimulus GO:0009607 97 0.022
cell morphogenesis involved in differentiation GO:0000904 195 0.022
positive regulation of cell cycle GO:0045787 3 0.022
maintenance of location GO:0051235 4 0.022
regulation of protein metabolic process GO:0051246 56 0.022
response to external biotic stimulus GO:0043207 97 0.021
heart looping GO:0001947 94 0.021
regulation of meiotic cell cycle GO:0051445 1 0.021
regulation of biosynthetic process GO:0009889 250 0.021
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.021
cellular response to extracellular stimulus GO:0031668 2 0.021
embryonic organ development GO:0048568 381 0.021
Mouse
positive regulation of cellular metabolic process GO:0031325 94 0.021
immune system process GO:0002376 241 0.021
nuclear import GO:0051170 3 0.021
regulation of neuron differentiation GO:0045664 56 0.021
phototransduction visible light GO:0007603 2 0.021
single organism transport GO:0044765 206 0.020
regulation of peptidase activity GO:0052547 23 0.020
response to other organism GO:0051707 97 0.020
response to bacterium GO:0009617 58 0.020
regulation of multicellular organismal development GO:2000026 223 0.020
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.020
regulation of developmental process GO:0050793 247 0.020
response to glucose GO:0009749 3 0.020
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.020
negative regulation of protein phosphorylation GO:0001933 4 0.019
response to organic substance GO:0010033 153 0.019
positive regulation of cellular component biogenesis GO:0044089 3 0.019
chemical homeostasis GO:0048878 49 0.019
protein metabolic process GO:0019538 183 0.019
regulation of nucleotide catabolic process GO:0030811 2 0.019
regulation of metal ion transport GO:0010959 4 0.019
regulation of multicellular organism growth GO:0040014 4 0.019
positive regulation of hydrolase activity GO:0051345 13 0.018
atp catabolic process GO:0006200 4 0.018
interaction with host GO:0051701 4 0.018
cation transmembrane transport GO:0098655 65 0.018
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 10 0.018
negative regulation of nuclear division GO:0051784 3 0.018
embryonic skeletal system development GO:0048706 97 0.018
Mouse
kidney development GO:0001822 92 0.018
Mouse
establishment of protein localization to organelle GO:0072594 4 0.018
transcription dna templated GO:0006351 181 0.018
negative regulation of kinase activity GO:0033673 4 0.018
meiotic cell cycle process GO:1903046 3 0.018
interspecies interaction between organisms GO:0044419 4 0.018
oxoacid metabolic process GO:0043436 31 0.017
Mouse
cellular response to stress GO:0033554 62 0.017
developmental growth GO:0048589 166 0.017
Mouse
modification of morphology or physiology of other organism GO:0035821 4 0.017
negative regulation of protein kinase activity GO:0006469 4 0.017
cellular transition metal ion homeostasis GO:0046916 3 0.017
response to monosaccharide GO:0034284 3 0.017
hormone biosynthetic process GO:0042446 3 0.017
developmental cell growth GO:0048588 52 0.017
transcription from rna polymerase ii promoter GO:0006366 80 0.017
positive regulation of programmed cell death GO:0043068 29 0.017
ion homeostasis GO:0050801 41 0.017
phosphorylation GO:0016310 69 0.016
hormone secretion GO:0046879 2 0.016
renal system development GO:0072001 94 0.016
Mouse
inorganic cation transmembrane transport GO:0098662 50 0.016
cellular ketone metabolic process GO:0042180 11 0.016
b cell differentiation GO:0030183 1 0.016
adult behavior GO:0030534 2 0.016
locomotion GO:0040011 313 0.016
cellular response to external stimulus GO:0071496 2 0.016
regulation of tube size GO:0035150 2 0.016
hemopoiesis GO:0030097 183 0.016
ion transport GO:0006811 114 0.016
phagocytosis GO:0006909 3 0.016
cellular response to chemical stimulus GO:0070887 157 0.016
regulation of cellular protein metabolic process GO:0032268 52 0.016
positive regulation of secretion GO:0051047 1 0.016
gtp metabolic process GO:0046039 4 0.016
cell death in response to oxidative stress GO:0036473 2 0.015
cellular hormone metabolic process GO:0034754 19 0.015
Human Mouse Rat
regulation of establishment of protein localization GO:0070201 4 0.015
neuron projection development GO:0031175 180 0.015
ras protein signal transduction GO:0007265 7 0.015
morphogenesis of an epithelium GO:0002009 333 0.015
Mouse
cellular localization GO:0051641 97 0.015
macroautophagy GO:0016236 1 0.015
cellular macromolecule biosynthetic process GO:0034645 224 0.015
spindle assembly GO:0051225 2 0.015
ovulation cycle process GO:0022602 2 0.015
neuron projection morphogenesis GO:0048812 161 0.015
positive regulation of catalytic activity GO:0043085 25 0.015
protein targeting to nucleus GO:0044744 3 0.015
catabolic process GO:0009056 32 0.015
multicellular organismal metabolic process GO:0044236 2 0.015
carbohydrate derivative metabolic process GO:1901135 61 0.015
regulation of hydrolase activity GO:0051336 28 0.015
regulation of cell morphogenesis GO:0022604 42 0.015
positive regulation of cytokine production GO:0001819 2 0.015
phototransduction GO:0007602 2 0.015
cellular biosynthetic process GO:0044249 286 0.015
Mouse
signal transduction GO:0007165 455 0.015
Zebrafish
defense response to bacterium GO:0042742 22 0.015
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.015
organic substance biosynthetic process GO:1901576 289 0.015
Mouse
translational initiation GO:0006413 3 0.014
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.014
regulation of apoptotic process GO:0042981 98 0.014
positive regulation of multi organism process GO:0043902 3 0.014
positive regulation of cellular process GO:0048522 201 0.014
transmembrane transport GO:0055085 120 0.014
regulation of purine nucleotide catabolic process GO:0033121 2 0.014
forebrain development GO:0030900 96 0.014
mitotic nuclear division GO:0007067 18 0.014
regulation of cell projection organization GO:0031344 44 0.014
amine metabolic process GO:0009308 2 0.014
regulation of gtpase activity GO:0043087 2 0.014
regulation of intracellular signal transduction GO:1902531 57 0.014
aromatic compound biosynthetic process GO:0019438 217 0.014
response to ketone GO:1901654 1 0.014
negative regulation of catalytic activity GO:0043086 21 0.014
regulation of oxidative stress induced cell death GO:1903201 2 0.014
tube closure GO:0060606 1 0.014
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.014
urogenital system development GO:0001655 97 0.014
Mouse
nitric oxide biosynthetic process GO:0006809 2 0.014
microtubule organizing center organization GO:0031023 1 0.014
collagen metabolic process GO:0032963 2 0.014
negative regulation of dna replication GO:0008156 2 0.013
cellular nitrogen compound biosynthetic process GO:0044271 218 0.013
organic cyclic compound biosynthetic process GO:1901362 223 0.013
regeneration GO:0031099 91 0.013
nucleobase containing small molecule metabolic process GO:0055086 32 0.013
negative regulation of autophagy GO:0010507 1 0.013
establishment of localization GO:0051234 244 0.013
cell surface receptor signaling pathway GO:0007166 325 0.013
programmed cell death GO:0012501 119 0.013
alpha amino acid metabolic process GO:1901605 3 0.013
golgi vesicle transport GO:0048193 3 0.013
axon development GO:0061564 166 0.013
regulation of cell communication GO:0010646 232 0.013
Zebrafish
regulation of ph GO:0006885 3 0.013
regulation of cell activation GO:0050865 1 0.013
calcium ion import GO:0070509 4 0.013
organic acid metabolic process GO:0006082 31 0.013
Mouse
cellular modified amino acid metabolic process GO:0006575 3 0.013
erk1 and erk2 cascade GO:0070371 4 0.013
neurological system process GO:0050877 62 0.013
Human
ketone biosynthetic process GO:0042181 2 0.013
regulation of cell shape GO:0008360 1 0.013
negative regulation of macromolecule metabolic process GO:0010605 76 0.013
stem cell division GO:0017145 1 0.013
regulation of cellular protein catabolic process GO:1903362 1 0.013
regulation of organ growth GO:0046620 3 0.013
regulation of multicellular organismal process GO:0051239 277 0.012
viral process GO:0016032 1 0.012
cell matrix adhesion GO:0007160 4 0.012
negative regulation of secretion GO:0051048 2 0.012
muscle tissue development GO:0060537 110 0.012
iron ion homeostasis GO:0055072 4 0.012
negative regulation of metabolic process GO:0009892 86 0.012
response to amine GO:0014075 1 0.012
small gtpase mediated signal transduction GO:0007264 8 0.012
cellular response to radiation GO:0071478 4 0.012
calcium mediated signaling GO:0019722 2 0.012
regulation of protein ubiquitination GO:0031396 3 0.012
response to abiotic stimulus GO:0009628 122 0.012
regulation of protein localization to nucleus GO:1900180 2 0.012
stem cell maintenance GO:0019827 4 0.012
positive regulation of nucleoside metabolic process GO:0045979 1 0.012
modification dependent protein catabolic process GO:0019941 3 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.012
cellular response to organic substance GO:0071310 105 0.012
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.012
protein import into nucleus GO:0006606 3 0.012
regulation of phosphate metabolic process GO:0019220 43 0.011
leukocyte homeostasis GO:0001776 2 0.011
periodic partitioning GO:0007365 1 0.011
positive regulation of gtpase activity GO:0043547 1 0.011
skeletal muscle tissue development GO:0007519 67 0.011
positive regulation of peptidase activity GO:0010952 10 0.011
ribonucleotide metabolic process GO:0009259 27 0.011
regulation of photoreceptor cell differentiation GO:0046532 2 0.011
organelle fusion GO:0048284 3 0.011
response to amphetamine GO:0001975 1 0.011
cell substrate adhesion GO:0031589 4 0.011
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.011
regulation of cell proliferation GO:0042127 37 0.011
positive regulation of cellular biosynthetic process GO:0031328 68 0.011
response to food GO:0032094 1 0.011
centrosome cycle GO:0007098 1 0.011
cilium morphogenesis GO:0060271 85 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
regulation of cell substrate adhesion GO:0010810 1 0.011
cellular component biogenesis GO:0044085 178 0.011
organic substance transport GO:0071702 58 0.011
determination of heart left right asymmetry GO:0061371 117 0.011
regulation of ion transmembrane transporter activity GO:0032412 2 0.011
multi organism cellular process GO:0044764 2 0.011
cellular response to vascular endothelial growth factor stimulus GO:0035924 3 0.011
regulation of nucleocytoplasmic transport GO:0046822 2 0.011
multicellular organismal macromolecule metabolic process GO:0044259 2 0.011
embryonic skeletal system morphogenesis GO:0048704 93 0.011
Mouse
female gonad development GO:0008585 4 0.011
nucleic acid metabolic process GO:0090304 244 0.011
positive regulation of nucleotide catabolic process GO:0030813 1 0.011
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.011
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.011
alternative mrna splicing via spliceosome GO:0000380 1 0.011
tissue regeneration GO:0042246 74 0.011
centrosome organization GO:0051297 1 0.010
response to nutrient GO:0007584 3 0.010
synaptic growth at neuromuscular junction GO:0051124 2 0.010
ion transmembrane transport GO:0034220 91 0.010
single organism nuclear import GO:1902593 3 0.010
chemosensory behavior GO:0007635 1 0.010
regulation of blood pressure GO:0008217 1 0.010
cellular protein metabolic process GO:0044267 129 0.010
mitotic dna integrity checkpoint GO:0044774 4 0.010
apoptotic process GO:0006915 116 0.010
positive regulation of nucleic acid templated transcription GO:1903508 57 0.010
membrane invagination GO:0010324 1 0.010
positive regulation of cysteine type endopeptidase activity GO:2001056 10 0.010
cellular iron ion homeostasis GO:0006879 3 0.010
regulation of endopeptidase activity GO:0052548 23 0.010
spermatid differentiation GO:0048515 2 0.010
cell migration involved in heart development GO:0060973 22 0.010
protein localization GO:0008104 40 0.010

rdh10b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.068
disease of metabolism DOID:0014667 0 0.038
lysosomal storage disease DOID:3211 0 0.038
inherited metabolic disorder DOID:655 0 0.038
musculoskeletal system disease DOID:17 0 0.026
nervous system disease DOID:863 0 0.022