Danio rerio

19 known processes

parvb

parvin, beta

(Aliases: zgc:73117,wu:fd02e01,fd02e01)

parvb biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular component morphogenesis GO:0032989 336 0.117
Human Worm
regulation of macromolecule metabolic process GO:0060255 317 0.097
larval development GO:0002164 2 0.094
Worm
cellular nitrogen compound biosynthetic process GO:0044271 218 0.092
cellular nitrogen compound metabolic process GO:0034641 290 0.092
nitrogen compound metabolic process GO:0006807 319 0.083
regulation of cellular metabolic process GO:0031323 320 0.081
cellular aromatic compound metabolic process GO:0006725 295 0.077
heterocycle metabolic process GO:0046483 290 0.073
embryo development ending in birth or egg hatching GO:0009792 271 0.072
Worm
organic substance biosynthetic process GO:1901576 289 0.070
nucleic acid metabolic process GO:0090304 244 0.069
regulation of cellular biosynthetic process GO:0031326 245 0.069
cellular component assembly involved in morphogenesis GO:0010927 107 0.069
Worm
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.068
organic cyclic compound biosynthetic process GO:1901362 223 0.065
regulation of gene expression GO:0010468 265 0.063
cellular biosynthetic process GO:0044249 286 0.062
heterocycle biosynthetic process GO:0018130 215 0.062
nucleic acid templated transcription GO:0097659 181 0.061
nucleobase containing compound metabolic process GO:0006139 274 0.061
regulation of primary metabolic process GO:0080090 311 0.061
regionalization GO:0003002 274 0.061
nuclear transport GO:0051169 4 0.060
regulation of metabolic process GO:0019222 359 0.060
rna biosynthetic process GO:0032774 181 0.058
organic cyclic compound metabolic process GO:1901360 301 0.058
cellular macromolecule metabolic process GO:0044260 391 0.057
aging GO:0007568 2 0.054
Worm
biosynthetic process GO:0009058 294 0.053
signal transduction GO:0007165 455 0.052
nucleobase containing compound biosynthetic process GO:0034654 205 0.052
cellular macromolecule biosynthetic process GO:0034645 224 0.052
muscle cell differentiation GO:0042692 139 0.051
Worm
single organism metabolic process GO:0044710 217 0.051
regulation of nitrogen compound metabolic process GO:0051171 251 0.050
regulation of biosynthetic process GO:0009889 250 0.047
cell surface receptor signaling pathway GO:0007166 325 0.047
heart development GO:0007507 313 0.047
nucleocytoplasmic transport GO:0006913 4 0.046
tube morphogenesis GO:0035239 349 0.046
single organism organelle organization GO:1902589 199 0.045
Human Worm
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.045
muscle cell development GO:0055001 115 0.044
Worm
rna metabolic process GO:0016070 219 0.043
establishment of protein localization to organelle GO:0072594 4 0.043
negative regulation of biological process GO:0048519 304 0.042
negative regulation of cellular process GO:0048523 283 0.042
transcription dna templated GO:0006351 181 0.041
cellular component assembly GO:0022607 170 0.041
Human Worm
embryonic organ morphogenesis GO:0048562 274 0.041
cellular response to external stimulus GO:0071496 2 0.040
organelle assembly GO:0070925 110 0.040
Worm
regulation of nucleic acid templated transcription GO:1903506 213 0.040
sensory organ development GO:0007423 393 0.040
maintenance of location GO:0051235 4 0.040
small molecule metabolic process GO:0044281 77 0.040
regulation of protein complex assembly GO:0043254 3 0.039
regulation of macromolecule biosynthetic process GO:0010556 225 0.039
regulation of developmental process GO:0050793 247 0.039
Human
regulation of transcription dna templated GO:0006355 213 0.039
aromatic compound biosynthetic process GO:0019438 217 0.038
organelle organization GO:0006996 227 0.038
Human Worm
regulation of multicellular organismal process GO:0051239 277 0.038
system process GO:0003008 185 0.038
regulation of rna biosynthetic process GO:2001141 213 0.037
head development GO:0060322 303 0.037
regulation of protein transport GO:0051223 3 0.037
chordate embryonic development GO:0043009 271 0.037
central nervous system development GO:0007417 387 0.037
regulation of rna metabolic process GO:0051252 224 0.037
response to drug GO:0042493 3 0.036
gene expression GO:0010467 252 0.036
immune system process GO:0002376 241 0.035
protein localization to nucleus GO:0034504 3 0.035
cell morphogenesis GO:0000902 289 0.035
Human
morphogenesis of an epithelium GO:0002009 333 0.034
organonitrogen compound metabolic process GO:1901564 74 0.034
phagocytosis GO:0006909 3 0.033
positive regulation of transport GO:0051050 2 0.033
brain development GO:0007420 293 0.032
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.031
blood vessel development GO:0001568 246 0.031
regulation of establishment of protein localization GO:0070201 4 0.031
cellular protein catabolic process GO:0044257 4 0.031
cellular amine metabolic process GO:0044106 2 0.030
muscle structure development GO:0061061 196 0.030
Worm Fly
protein import GO:0017038 3 0.030
regulation of response to stimulus GO:0048583 269 0.029
embryonic organ development GO:0048568 381 0.029
neuron differentiation GO:0030182 353 0.029
positive regulation of cytokine production GO:0001819 2 0.029
positive regulation of cell cycle GO:0045787 3 0.029
single organism nuclear import GO:1902593 3 0.029
macromolecule biosynthetic process GO:0009059 227 0.029
regulation of cell communication GO:0010646 232 0.029
amine metabolic process GO:0009308 2 0.029
oxoacid metabolic process GO:0043436 31 0.029
regulation of cytokine production GO:0001817 3 0.029
cognition GO:0050890 1 0.028
response to stress GO:0006950 263 0.028
regulation of protein catabolic process GO:0042176 1 0.028
cellular component biogenesis GO:0044085 178 0.028
Human Worm
female gonad development GO:0008585 4 0.028
myofibril assembly GO:0030239 48 0.028
Worm
regulation of cell shape GO:0008360 1 0.028
Human
response to external stimulus GO:0009605 264 0.028
positive regulation of catabolic process GO:0009896 4 0.028
vasculature development GO:0001944 278 0.028
response to chemical GO:0042221 320 0.027
regulation of protein targeting GO:1903533 2 0.026
cell cycle g1 s phase transition GO:0044843 1 0.026
lipid storage GO:0019915 1 0.026
striated muscle cell differentiation GO:0051146 129 0.026
Worm
regulation of cellular ketone metabolic process GO:0010565 7 0.025
development of primary female sexual characteristics GO:0046545 4 0.025
cytokinesis GO:0000910 3 0.025
response to nutrient GO:0007584 3 0.025
striated muscle cell development GO:0055002 108 0.025
Worm
positive regulation of cellular catabolic process GO:0031331 3 0.025
specification of symmetry GO:0009799 204 0.024
regulation of protein localization to nucleus GO:1900180 2 0.024
protein metabolic process GO:0019538 183 0.024
Worm
organic acid metabolic process GO:0006082 31 0.024
regulation of intracellular protein transport GO:0033157 3 0.024
eye development GO:0001654 277 0.024
negative regulation of response to stimulus GO:0048585 104 0.024
regulation of signal transduction GO:0009966 225 0.024
cell projection organization GO:0030030 284 0.024
Human
cellular response to nutrient levels GO:0031669 2 0.024
regulation of reactive oxygen species metabolic process GO:2000377 2 0.024
protein import into nucleus GO:0006606 3 0.023
i kappab kinase nf kappab signaling GO:0007249 4 0.023
positive regulation of cellular process GO:0048522 201 0.023
negative regulation of protein phosphorylation GO:0001933 4 0.023
gastrulation GO:0007369 208 0.023
regulation of protein import into nucleus GO:0042306 2 0.023
multicellular organism growth GO:0035264 4 0.023
protein targeting to nucleus GO:0044744 3 0.023
regulation of cellular amine metabolic process GO:0033238 0 0.023
regulation of nucleocytoplasmic transport GO:0046822 2 0.022
multi organism process GO:0051704 134 0.022
transcription from rna polymerase ii promoter GO:0006366 80 0.022
immune system development GO:0002520 191 0.022
regulation of cellular amino acid metabolic process GO:0006521 0 0.022
cellular response to chemical stimulus GO:0070887 157 0.022
proteasomal protein catabolic process GO:0010498 2 0.022
striated muscle tissue development GO:0014706 110 0.022
locomotion GO:0040011 313 0.022
Worm
digestive system development GO:0055123 289 0.022
cell projection morphogenesis GO:0048858 244 0.022
negative regulation of metabolic process GO:0009892 86 0.022
actin filament based process GO:0030029 64 0.022
Human Worm
cellular response to extracellular stimulus GO:0031668 2 0.022
regulation of anatomical structure morphogenesis GO:0022603 130 0.021
Human
negative regulation of protein kinase activity GO:0006469 4 0.021
heart process GO:0003015 71 0.021
positive regulation of cellular component biogenesis GO:0044089 3 0.021
establishment of localization GO:0051234 244 0.021
female sex differentiation GO:0046660 4 0.021
mitochondrion organization GO:0007005 4 0.021
carboxylic acid metabolic process GO:0019752 22 0.021
cellular component movement GO:0006928 335 0.021
regulation of binding GO:0051098 3 0.021
muscle tissue development GO:0060537 110 0.021
negative regulation of signal transduction GO:0009968 94 0.021
generation of neurons GO:0048699 385 0.021
blood circulation GO:0008015 87 0.020
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.020
heart morphogenesis GO:0003007 156 0.020
meiotic nuclear division GO:0007126 4 0.020
cell death GO:0008219 121 0.020
nuclear import GO:0051170 3 0.020
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.020
regulation of autophagy GO:0010506 3 0.020
cellular component disassembly GO:0022411 1 0.020
cell part morphogenesis GO:0032990 246 0.020
regulation of cell activation GO:0050865 1 0.020
skeletal muscle tissue development GO:0007519 67 0.020
gtp metabolic process GO:0046039 4 0.020
regulation of reproductive process GO:2000241 4 0.020
positive regulation of cellular amine metabolic process GO:0033240 0 0.020
modification dependent macromolecule catabolic process GO:0043632 3 0.020
stem cell proliferation GO:0072089 4 0.020
phosphorus metabolic process GO:0006793 109 0.020
phosphate containing compound metabolic process GO:0006796 108 0.020
localization of cell GO:0051674 244 0.020
regulation of signaling GO:0023051 235 0.020
autophagy GO:0006914 4 0.020
extrinsic apoptotic signaling pathway GO:0097191 3 0.020
cellular carbohydrate metabolic process GO:0044262 4 0.019
cartilage condensation GO:0001502 3 0.019
wnt signaling pathway GO:0016055 80 0.019
cell motility GO:0048870 244 0.019
tissue remodeling GO:0048771 4 0.019
regulation of inflammatory response GO:0050727 2 0.019
guanosine containing compound metabolic process GO:1901068 4 0.019
transport GO:0006810 220 0.019
regulation of cell differentiation GO:0045595 142 0.019
negative regulation of multicellular organismal process GO:0051241 69 0.019
cell migration GO:0016477 237 0.019
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.019
negative regulation of macromolecule metabolic process GO:0010605 76 0.019
negative regulation of kinase activity GO:0033673 4 0.019
guanosine containing compound catabolic process GO:1901069 2 0.019
positive regulation of biological process GO:0048518 253 0.019
cellular amino acid metabolic process GO:0006520 7 0.019
modification dependent protein catabolic process GO:0019941 3 0.019
ubiquitin dependent protein catabolic process GO:0006511 3 0.019
programmed cell death GO:0012501 119 0.019
regulation of organ growth GO:0046620 3 0.019
angiogenesis GO:0001525 158 0.019
regulation of apoptotic process GO:0042981 98 0.018
negative regulation of catabolic process GO:0009895 3 0.018
skeletal system development GO:0001501 181 0.018
cellular ketone metabolic process GO:0042180 11 0.018
gtp catabolic process GO:0006184 2 0.018
regulation of meiotic cell cycle GO:0051445 1 0.018
nuclear export GO:0051168 1 0.018
response to organic substance GO:0010033 153 0.018
developmental growth GO:0048589 166 0.018
regulation of synapse organization GO:0050807 3 0.018
regulation of biological quality GO:0065008 263 0.018
Human
response to abiotic stimulus GO:0009628 122 0.018
epithelial tube morphogenesis GO:0060562 148 0.018
regulation of multicellular organism growth GO:0040014 4 0.018
g1 s transition of mitotic cell cycle GO:0000082 1 0.018
cellular response to starvation GO:0009267 1 0.018
regulation of multicellular organismal development GO:2000026 223 0.018
digestive tract morphogenesis GO:0048546 231 0.018
carbohydrate homeostasis GO:0033500 1 0.017
growth GO:0040007 174 0.017
phagocytosis engulfment GO:0006911 1 0.017
regulation of protein ubiquitination GO:0031396 3 0.017
regulation of cytoplasmic transport GO:1903649 4 0.017
stem cell maintenance GO:0019827 4 0.017
cellular protein metabolic process GO:0044267 129 0.017
positive regulation of secretion GO:0051047 1 0.017
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.017
regulation of stem cell proliferation GO:0072091 2 0.017
regulation of cell death GO:0010941 103 0.017
regulation of nucleoside metabolic process GO:0009118 2 0.017
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.017
positive regulation of cellular metabolic process GO:0031325 94 0.016
hematopoietic or lymphoid organ development GO:0048534 191 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.016
protein polymerization GO:0051258 4 0.016
skeletal muscle organ development GO:0060538 78 0.016
Fly
intracellular signal transduction GO:0035556 85 0.016
protein secretion GO:0009306 1 0.016
regulation of purine nucleotide catabolic process GO:0033121 2 0.016
digestive tract development GO:0048565 265 0.016
cell cycle GO:0007049 93 0.016
response to carbohydrate GO:0009743 3 0.016
regulation of gtp catabolic process GO:0033124 2 0.015
regulation of stem cell differentiation GO:2000736 4 0.015
negative regulation of developmental process GO:0051093 65 0.015
positive regulation of cell adhesion GO:0045785 1 0.015
gland development GO:0048732 143 0.015
microtubule organizing center organization GO:0031023 1 0.015
blood vessel morphogenesis GO:0048514 216 0.015
regulation of muscle contraction GO:0006937 3 0.015
regulation of mrna processing GO:0050684 3 0.015
positive regulation of secretion by cell GO:1903532 1 0.015
mononuclear cell proliferation GO:0032943 1 0.015
determination of heart left right asymmetry GO:0061371 117 0.015
circulatory system process GO:0003013 87 0.015
negative regulation of gene expression GO:0010629 65 0.015
cellular response to radiation GO:0071478 4 0.015
cytoskeleton organization GO:0007010 96 0.015
Human Worm
regulation of blood pressure GO:0008217 1 0.015
response to monosaccharide GO:0034284 3 0.015
regulation of organelle assembly GO:1902115 4 0.015
anterior posterior pattern specification GO:0009952 152 0.015
single organism localization GO:1902578 225 0.014
positive regulation of metabolic process GO:0009893 108 0.014
camera type eye development GO:0043010 222 0.014
skeletal system morphogenesis GO:0048705 102 0.014
production of molecular mediator of immune response GO:0002440 2 0.014
cellular response to organic substance GO:0071310 105 0.014
negative regulation of cellular catabolic process GO:0031330 3 0.014
regulation of nucleotide catabolic process GO:0030811 2 0.014
protein acylation GO:0043543 3 0.014
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.014
negative regulation of signaling GO:0023057 96 0.014
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.014
regulation of cellular protein catabolic process GO:1903362 1 0.014
muscle organ development GO:0007517 101 0.014
Fly
erk1 and erk2 cascade GO:0070371 4 0.014
b cell activation GO:0042113 2 0.014
convergent extension GO:0060026 118 0.014
regulation of cell development GO:0060284 100 0.014
cell proliferation GO:0008283 80 0.014
response to hexose GO:0009746 3 0.014
cell substrate adhesion GO:0031589 4 0.014
regulation of neural precursor cell proliferation GO:2000177 3 0.014
protein stabilization GO:0050821 2 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.014
centrosome organization GO:0051297 1 0.014
somatic stem cell maintenance GO:0035019 1 0.013
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.013
sensory system development GO:0048880 76 0.013
regulation of response to biotic stimulus GO:0002831 2 0.013
positive regulation of transcription dna templated GO:0045893 57 0.013
regulation of metal ion transport GO:0010959 4 0.013
telomere maintenance GO:0000723 1 0.013
positive regulation of macromolecule metabolic process GO:0010604 93 0.013
positive regulation of cell activation GO:0050867 1 0.013
cellular amide metabolic process GO:0043603 4 0.013
determination of bilateral symmetry GO:0009855 204 0.013
regulation of localization GO:0032879 104 0.013
enzyme linked receptor protein signaling pathway GO:0007167 106 0.013
negative regulation of cellular metabolic process GO:0031324 77 0.013
response to external biotic stimulus GO:0043207 97 0.013
regulation of dna replication GO:0006275 3 0.013
peptide transport GO:0015833 1 0.013
lateral line system development GO:0048925 76 0.013
peptidyl lysine acetylation GO:0018394 2 0.013
segmentation GO:0035282 97 0.013
positive regulation of biosynthetic process GO:0009891 68 0.013
meiotic cell cycle process GO:1903046 3 0.013
response to corticosteroid GO:0031960 1 0.013
negative regulation of dna metabolic process GO:0051053 4 0.013
connective tissue development GO:0061448 99 0.013
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.013
positive regulation of nucleotide catabolic process GO:0030813 1 0.013
macromolecular complex disassembly GO:0032984 1 0.013
glucose homeostasis GO:0042593 1 0.012
hemopoiesis GO:0030097 183 0.012
positive regulation of map kinase activity GO:0043406 3 0.012
leukocyte proliferation GO:0070661 1 0.012
cranial ganglion development GO:0061550 3 0.012
cartilage development GO:0051216 96 0.012
canonical wnt signaling pathway GO:0060070 48 0.012
regulation of programmed cell death GO:0043067 101 0.012
protein acetylation GO:0006473 2 0.012
cytoskeleton dependent cytokinesis GO:0061640 3 0.012
negative regulation of cytokine production GO:0001818 1 0.012
cellular protein modification process GO:0006464 100 0.012
developmental programmed cell death GO:0010623 4 0.012
negative regulation of secretion by cell GO:1903531 2 0.012
adult behavior GO:0030534 2 0.012
apoptotic process GO:0006915 116 0.012
regulation of gtpase activity GO:0043087 2 0.012
death GO:0016265 121 0.012
nucleoside monophosphate catabolic process GO:0009125 4 0.012
positive regulation of cellular biosynthetic process GO:0031328 68 0.012
anatomical structure arrangement GO:0048532 2 0.012
cellular localization GO:0051641 97 0.012
regulation of jun kinase activity GO:0043506 3 0.012
negative regulation of mapk cascade GO:0043409 4 0.012
regulation of synaptic plasticity GO:0048167 1 0.012
regulation of tube size GO:0035150 2 0.012
neuroblast proliferation GO:0007405 2 0.012
positive regulation of stem cell proliferation GO:2000648 1 0.012
membrane fusion GO:0061025 2 0.012
regulation of circadian rhythm GO:0042752 4 0.012
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.012
regulation of mrna splicing via spliceosome GO:0048024 3 0.012
internal protein amino acid acetylation GO:0006475 2 0.012
regulation of erk1 and erk2 cascade GO:0070372 4 0.012
cell morphogenesis involved in differentiation GO:0000904 195 0.012
regulation of protein polymerization GO:0032271 2 0.012
alternative mrna splicing via spliceosome GO:0000380 1 0.012
regulation of production of molecular mediator of immune response GO:0002700 1 0.012
homeostatic process GO:0042592 142 0.012
positive regulation of stress activated mapk cascade GO:0032874 3 0.012
macromolecule modification GO:0043412 111 0.012
behavior GO:0007610 74 0.011
lipid homeostasis GO:0055088 3 0.011
double strand break repair GO:0006302 3 0.011
negative regulation of defense response GO:0031348 2 0.011
regulation of blood vessel size GO:0050880 2 0.011
negative regulation of cell communication GO:0010648 96 0.011
negative regulation of cellular biosynthetic process GO:0031327 55 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.011
carbohydrate derivative metabolic process GO:1901135 61 0.011
neuron development GO:0048666 262 0.011
regulation of chromosome segregation GO:0051983 1 0.011
cellular response to oxygen levels GO:0071453 1 0.011
negative regulation of cell differentiation GO:0045596 46 0.011
multi organism cellular process GO:0044764 2 0.011
single organism transport GO:0044765 206 0.011
positive regulation of response to stimulus GO:0048584 80 0.011
regulation of wnt signaling pathway GO:0030111 53 0.011
membrane invagination GO:0010324 1 0.011
protein heterooligomerization GO:0051291 1 0.011
lymphocyte proliferation GO:0046651 1 0.011
dorsal ventral pattern formation GO:0009953 125 0.011
actin cytoskeleton organization GO:0030036 63 0.011
Human Worm
positive regulation of translation GO:0045727 1 0.011
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.011
inositol lipid mediated signaling GO:0048017 2 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.011
sensory organ morphogenesis GO:0090596 200 0.011
phosphorylation GO:0016310 69 0.011
positive regulation of gene expression GO:0010628 71 0.011
olfactory bulb development GO:0021772 4 0.011
regulation of cellular component organization GO:0051128 86 0.011
Human
meiotic chromosome segregation GO:0045132 3 0.011
adherens junction organization GO:0034332 4 0.011
positive regulation of rna metabolic process GO:0051254 59 0.011
regulation of cell substrate adhesion GO:0010810 1 0.011
response to uv GO:0009411 3 0.011
stem cell differentiation GO:0048863 117 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.011
negative regulation of biosynthetic process GO:0009890 55 0.011
ribonucleoside monophosphate catabolic process GO:0009158 4 0.011
signal transduction in absence of ligand GO:0038034 1 0.011
heart contraction GO:0060047 71 0.011
neuronal action potential GO:0019228 18 0.010
biological adhesion GO:0022610 40 0.010
cardiac muscle tissue development GO:0048738 48 0.010
interspecies interaction between organisms GO:0044419 4 0.010
sleep GO:0030431 1 0.010
outflow tract morphogenesis GO:0003151 1 0.010
positive regulation of dna metabolic process GO:0051054 1 0.010
positive regulation of gtp catabolic process GO:0033126 1 0.010
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.010
atp catabolic process GO:0006200 4 0.010
rna localization GO:0006403 4 0.010
ear development GO:0043583 127 0.010
negative regulation of multi organism process GO:0043901 3 0.010
determination of left right symmetry GO:0007368 179 0.010

parvb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.043
nervous system disease DOID:863 0 0.020
cancer DOID:162 0 0.017
disease of cellular proliferation DOID:14566 0 0.017
organ system cancer DOID:0050686 0 0.017
sensory system disease DOID:0050155 0 0.013
eye and adnexa disease DOID:1492 0 0.013
eye disease DOID:5614 0 0.013