Danio rerio

0 known processes

xrcc4

X-ray repair complementing defective repair in Chinese hamster cells 4

(Aliases: MGC73312,zgc:73312)

xrcc4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.083
aging GO:0007568 2 0.048
signal transduction GO:0007165 455 0.048
regulation of protein complex assembly GO:0043254 3 0.047
nitrogen compound metabolic process GO:0006807 319 0.044
positive regulation of cellular component biogenesis GO:0044089 3 0.042
gtp metabolic process GO:0046039 4 0.041
guanosine containing compound metabolic process GO:1901068 4 0.040
positive regulation of transport GO:0051050 2 0.038
gtp catabolic process GO:0006184 2 0.038
single organism membrane fusion GO:0044801 2 0.037
regulation of cell shape GO:0008360 1 0.036
cellular macromolecule metabolic process GO:0044260 391 0.035
golgi vesicle transport GO:0048193 3 0.035
organic substance biosynthetic process GO:1901576 289 0.035
regulation of cellular metabolic process GO:0031323 320 0.035
establishment of protein localization to organelle GO:0072594 4 0.034
actin polymerization or depolymerization GO:0008154 2 0.034
guanosine containing compound catabolic process GO:1901069 2 0.034
regulation of metabolic process GO:0019222 359 0.034
maintenance of location GO:0051235 4 0.033
cellular nitrogen compound metabolic process GO:0034641 290 0.033
cognition GO:0050890 1 0.032
cytokinesis GO:0000910 3 0.032
protein polymerization GO:0051258 4 0.032
membrane fusion GO:0061025 2 0.032
cell morphogenesis GO:0000902 289 0.032
central nervous system development GO:0007417 387 0.031
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.031
regulation of establishment of protein localization GO:0070201 4 0.031
organelle fusion GO:0048284 3 0.031
organic cyclic compound metabolic process GO:1901360 301 0.030
endosomal transport GO:0016197 2 0.030
phagocytosis GO:0006909 3 0.030
amine metabolic process GO:0009308 2 0.030
organonitrogen compound metabolic process GO:1901564 74 0.030
nucleobase containing compound metabolic process GO:0006139 274 0.030
response to stress GO:0006950 263 0.029
neuron differentiation GO:0030182 353 0.029
cellular biosynthetic process GO:0044249 286 0.029
response to drug GO:0042493 3 0.029
protein localization to plasma membrane GO:0072659 1 0.028
regulation of primary metabolic process GO:0080090 311 0.028
cellular carbohydrate metabolic process GO:0044262 4 0.028
head development GO:0060322 303 0.028
cellular amine metabolic process GO:0044106 2 0.028
regulation of protein transport GO:0051223 3 0.028
response to chemical GO:0042221 320 0.027
cell surface receptor signaling pathway GO:0007166 325 0.027
cellular response to external stimulus GO:0071496 2 0.027
cellular aromatic compound metabolic process GO:0006725 295 0.027
generation of neurons GO:0048699 385 0.027
regulation of binding GO:0051098 3 0.027
gene expression GO:0010467 252 0.027
regulation of macromolecule metabolic process GO:0060255 317 0.027
cellular component morphogenesis GO:0032989 336 0.027
regulation of nitrogen compound metabolic process GO:0051171 251 0.027
cellular component movement GO:0006928 335 0.026
biosynthetic process GO:0009058 294 0.026
cellular macromolecule biosynthetic process GO:0034645 224 0.026
heterocycle metabolic process GO:0046483 290 0.026
multicellular organism growth GO:0035264 4 0.026
positive regulation of catabolic process GO:0009896 4 0.026
regulation of synapse organization GO:0050807 3 0.025
regulation of protein polymerization GO:0032271 2 0.025
regulation of synapse assembly GO:0051963 3 0.025
cellular response to extracellular stimulus GO:0031668 2 0.025
negative regulation of biological process GO:0048519 304 0.025
determination of bilateral symmetry GO:0009855 204 0.025
cell projection organization GO:0030030 284 0.025
regulation of cellular biosynthetic process GO:0031326 245 0.025
nuclear transport GO:0051169 4 0.025
locomotion GO:0040011 313 0.025
single organism localization GO:1902578 225 0.024
negative regulation of cellular process GO:0048523 283 0.024
actin filament polymerization GO:0030041 2 0.024
regulation of reproductive process GO:2000241 4 0.024
single organism metabolic process GO:0044710 217 0.024
regionalization GO:0003002 274 0.024
protein localization to nucleus GO:0034504 3 0.024
cell migration GO:0016477 237 0.024
autophagy GO:0006914 4 0.024
regulation of nucleoside metabolic process GO:0009118 2 0.024
synaptic growth at neuromuscular junction GO:0051124 2 0.024
morphogenesis of an epithelium GO:0002009 333 0.024
cell part morphogenesis GO:0032990 246 0.024
cellular response to nutrient levels GO:0031669 2 0.023
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.023
single organism organelle organization GO:1902589 199 0.023
brain development GO:0007420 293 0.023
cellular component assembly GO:0022607 170 0.023
positive regulation of cellular catabolic process GO:0031331 3 0.023
cellular component biogenesis GO:0044085 178 0.023
positive regulation of cell cycle GO:0045787 3 0.022
cell projection morphogenesis GO:0048858 244 0.022
establishment of localization GO:0051234 244 0.022
meiotic nuclear division GO:0007126 4 0.022
regulation of cell communication GO:0010646 232 0.022
rna metabolic process GO:0016070 219 0.022
negative regulation of protein phosphorylation GO:0001933 4 0.022
lamellipodium assembly GO:0030032 1 0.022
regulation of gene expression GO:0010468 265 0.022
cellular response to starvation GO:0009267 1 0.022
stem cell maintenance GO:0019827 4 0.022
negative regulation of synapse assembly GO:0051964 2 0.022
negative regulation of kinase activity GO:0033673 4 0.022
regulation of meiotic cell cycle GO:0051445 1 0.022
stem cell proliferation GO:0072089 4 0.022
regulation of multicellular organism growth GO:0040014 4 0.021
regulation of signal transduction GO:0009966 225 0.021
positive regulation of biological process GO:0048518 253 0.021
cellular response to chemical stimulus GO:0070887 157 0.021
regulation of gtp catabolic process GO:0033124 2 0.021
cell substrate adhesion GO:0031589 4 0.021
regulation of protein localization to nucleus GO:1900180 2 0.021
heterocycle biosynthetic process GO:0018130 215 0.021
nucleic acid metabolic process GO:0090304 244 0.021
embryo development ending in birth or egg hatching GO:0009792 271 0.021
transcription dna templated GO:0006351 181 0.021
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.020
specification of symmetry GO:0009799 204 0.020
regulation of biological quality GO:0065008 263 0.020
cell motility GO:0048870 244 0.020
ubiquitin dependent protein catabolic process GO:0006511 3 0.020
proteasomal protein catabolic process GO:0010498 2 0.020
regulation of cell activation GO:0050865 1 0.020
macromolecule biosynthetic process GO:0009059 227 0.020
regulation of cellular amino acid metabolic process GO:0006521 0 0.020
tube morphogenesis GO:0035239 349 0.020
regulation of cellular ketone metabolic process GO:0010565 7 0.020
chordate embryonic development GO:0043009 271 0.020
cellular ketone metabolic process GO:0042180 11 0.020
lamellipodium organization GO:0097581 1 0.020
regulation of nucleotide catabolic process GO:0030811 2 0.020
regulation of biosynthetic process GO:0009889 250 0.020
response to external stimulus GO:0009605 264 0.020
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.020
blood vessel development GO:0001568 246 0.019
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.019
negative regulation of protein kinase activity GO:0006469 4 0.019
meiotic cell cycle process GO:1903046 3 0.019
cellular component disassembly GO:0022411 1 0.019
modification dependent macromolecule catabolic process GO:0043632 3 0.019
protein import GO:0017038 3 0.019
regulation of response to stimulus GO:0048583 269 0.019
positive regulation of nucleotide catabolic process GO:0030813 1 0.019
regulation of purine nucleotide catabolic process GO:0033121 2 0.019
immune system process GO:0002376 241 0.019
organelle organization GO:0006996 227 0.019
positive regulation of gtp catabolic process GO:0033126 1 0.019
digestive system development GO:0055123 289 0.019
small molecule metabolic process GO:0044281 77 0.019
regulation of metal ion transport GO:0010959 4 0.019
carboxylic acid metabolic process GO:0019752 22 0.018
regulation of signaling GO:0023051 235 0.018
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.018
actin filament based process GO:0030029 64 0.018
positive regulation of secretion GO:0051047 1 0.018
positive regulation of secretion by cell GO:1903532 1 0.018
response to organic substance GO:0010033 153 0.018
nucleobase containing compound biosynthetic process GO:0034654 205 0.018
cellular nitrogen compound biosynthetic process GO:0044271 218 0.018
convergent extension GO:0060026 118 0.018
protein metabolic process GO:0019538 183 0.018
protein secretion GO:0009306 1 0.018
lipid storage GO:0019915 1 0.018
nucleocytoplasmic transport GO:0006913 4 0.018
regulation of gtpase activity GO:0043087 2 0.018
positive regulation of cytoskeleton organization GO:0051495 3 0.018
exocytosis GO:0006887 1 0.018
positive regulation of nucleoside metabolic process GO:0045979 1 0.018
neuroblast proliferation GO:0007405 2 0.018
embryonic organ development GO:0048568 381 0.018
regulation of macromolecule biosynthetic process GO:0010556 225 0.017
regulation of protein targeting GO:1903533 2 0.017
determination of left right symmetry GO:0007368 179 0.017
regulation of cellular amine metabolic process GO:0033238 0 0.017
cellular amino acid metabolic process GO:0006520 7 0.017
single organism transport GO:0044765 206 0.017
stem cell division GO:0017145 1 0.017
establishment of protein localization to plasma membrane GO:0090002 1 0.017
nucleic acid templated transcription GO:0097659 181 0.017
regulation of carbohydrate metabolic process GO:0006109 4 0.017
positive regulation of gtpase activity GO:0043547 1 0.017
regulation of multicellular organismal process GO:0051239 277 0.017
single organism nuclear import GO:1902593 3 0.017
er to golgi vesicle mediated transport GO:0006888 1 0.017
angiogenesis GO:0001525 158 0.017
secondary metabolic process GO:0019748 3 0.017
neuron development GO:0048666 262 0.017
centrosome organization GO:0051297 1 0.017
female sex differentiation GO:0046660 4 0.017
system process GO:0003008 185 0.016
regulation of rna metabolic process GO:0051252 224 0.016
eye development GO:0001654 277 0.016
aromatic compound biosynthetic process GO:0019438 217 0.016
macroautophagy GO:0016236 1 0.016
cell matrix adhesion GO:0007160 4 0.016
regulation of cytoplasmic transport GO:1903649 4 0.016
regulation of protein catabolic process GO:0042176 1 0.016
muscle structure development GO:0061061 196 0.016
regulation of developmental process GO:0050793 247 0.016
organic cyclic compound biosynthetic process GO:1901362 223 0.016
vasculature development GO:0001944 278 0.016
heart development GO:0007507 313 0.016
chemosensory behavior GO:0007635 1 0.016
cell cycle g1 s phase transition GO:0044843 1 0.016
mononuclear cell proliferation GO:0032943 1 0.016
localization of cell GO:0051674 244 0.016
positive regulation of cell adhesion GO:0045785 1 0.016
cytoskeleton dependent cytokinesis GO:0061640 3 0.016
g1 s transition of mitotic cell cycle GO:0000082 1 0.016
leukocyte proliferation GO:0070661 1 0.016
nuclear import GO:0051170 3 0.016
protein complex disassembly GO:0043241 1 0.016
positive regulation of protein complex assembly GO:0031334 2 0.016
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.016
transport GO:0006810 220 0.016
regulation of rna biosynthetic process GO:2001141 213 0.015
regulation of mrna processing GO:0050684 3 0.015
organic acid metabolic process GO:0006082 31 0.015
peptidyl serine modification GO:0018209 2 0.015
sensory organ development GO:0007423 393 0.015
response to carbohydrate GO:0009743 3 0.015
translational initiation GO:0006413 3 0.015
positive regulation of cellular process GO:0048522 201 0.015
oxoacid metabolic process GO:0043436 31 0.015
cellular protein catabolic process GO:0044257 4 0.015
cellular extravasation GO:0045123 1 0.015
digestive tract morphogenesis GO:0048546 231 0.015
negative regulation of defense response GO:0031348 2 0.015
post golgi vesicle mediated transport GO:0006892 1 0.015
locomotor rhythm GO:0045475 3 0.015
cellular response to organic substance GO:0071310 105 0.015
membrane invagination GO:0010324 1 0.015
regulation of autophagy GO:0010506 3 0.015
neuron projection development GO:0031175 180 0.015
macromolecular complex disassembly GO:0032984 1 0.015
response to topologically incorrect protein GO:0035966 2 0.015
rna localization GO:0006403 4 0.015
cytoplasm organization GO:0007028 4 0.015
mitochondrion organization GO:0007005 4 0.014
regulation of protein import into nucleus GO:0042306 2 0.014
modification dependent protein catabolic process GO:0019941 3 0.014
regulation of inflammatory response GO:0050727 2 0.014
fertilization GO:0009566 3 0.014
embryonic organ morphogenesis GO:0048562 274 0.014
extrinsic apoptotic signaling pathway GO:0097191 3 0.014
female gonad development GO:0008585 4 0.014
negative regulation of response to stimulus GO:0048585 104 0.014
phagocytosis engulfment GO:0006911 1 0.014
actin cytoskeleton organization GO:0030036 63 0.014
cortical cytoskeleton organization GO:0030865 1 0.014
gland development GO:0048732 143 0.014
regulation of cytokine production GO:0001817 3 0.014
positive regulation of cellular amine metabolic process GO:0033240 0 0.014
regulation of protein binding GO:0043393 3 0.014
transmembrane transport GO:0055085 120 0.014
regulation of cell substrate adhesion GO:0010810 1 0.014
cytoskeleton organization GO:0007010 96 0.014
lateral inhibition GO:0046331 1 0.013
regulation of stem cell differentiation GO:2000736 4 0.013
striated muscle cell differentiation GO:0051146 129 0.013
regulation of cell projection assembly GO:0060491 4 0.013
carbohydrate biosynthetic process GO:0016051 1 0.013
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.013
ribonucleoside monophosphate catabolic process GO:0009158 4 0.013
transcription from rna polymerase ii promoter GO:0006366 80 0.013
cell morphogenesis involved in differentiation GO:0000904 195 0.013
cellular component assembly involved in morphogenesis GO:0010927 107 0.013
regulation of nucleocytoplasmic transport GO:0046822 2 0.013
epithelial tube morphogenesis GO:0060562 148 0.013
growth GO:0040007 174 0.013
response to nutrient GO:0007584 3 0.013
cilium morphogenesis GO:0060271 85 0.013
negative regulation of catabolic process GO:0009895 3 0.013
rna biosynthetic process GO:0032774 181 0.013
development of primary female sexual characteristics GO:0046545 4 0.013
phosphorus metabolic process GO:0006793 109 0.013
response to external biotic stimulus GO:0043207 97 0.013
regulation of multicellular organismal development GO:2000026 223 0.013
cellular localization GO:0051641 97 0.013
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.013
protein import into nucleus GO:0006606 3 0.013
adult behavior GO:0030534 2 0.013
germ line stem cell maintenance GO:0030718 2 0.013
carbohydrate homeostasis GO:0033500 1 0.013
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.013
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.013
positive regulation of cell activation GO:0050867 1 0.013
production of molecular mediator of immune response GO:0002440 2 0.013
protein targeting to nucleus GO:0044744 3 0.012
cellular biogenic amine metabolic process GO:0006576 2 0.012
muscle cell differentiation GO:0042692 139 0.012
cortical actin cytoskeleton organization GO:0030866 1 0.012
cell projection assembly GO:0030031 64 0.012
internal protein amino acid acetylation GO:0006475 2 0.012
gastrulation GO:0007369 208 0.012
pole plasm assembly GO:0007315 4 0.012
ameboidal type cell migration GO:0001667 143 0.012
developmental growth GO:0048589 166 0.012
negative regulation of protein complex assembly GO:0031333 1 0.012
negative regulation of metabolic process GO:0009892 86 0.012
regulation of transporter activity GO:0032409 2 0.012
blood vessel morphogenesis GO:0048514 216 0.012
mitotic cell cycle GO:0000278 64 0.012
axon development GO:0061564 166 0.012
response to glucose GO:0009749 3 0.012
negative regulation of signaling GO:0023057 96 0.012
cellular response to endogenous stimulus GO:0071495 68 0.012
nuclear migration GO:0007097 3 0.012
regulation of transcription dna templated GO:0006355 213 0.012
anterior posterior pattern specification GO:0009952 152 0.012
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.012
signal transduction in absence of ligand GO:0038034 1 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.011
response to other organism GO:0051707 97 0.011
microtubule organizing center organization GO:0031023 1 0.011
compound eye development GO:0048749 2 0.011
phosphatidylinositol mediated signaling GO:0048015 2 0.011
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.011
phosphate containing compound metabolic process GO:0006796 108 0.011
regulation of neural precursor cell proliferation GO:2000177 3 0.011
determination of heart left right asymmetry GO:0061371 117 0.011
actin filament based movement GO:0030048 1 0.011
spermatid differentiation GO:0048515 2 0.011
regulation of intracellular protein transport GO:0033157 3 0.011
response to wounding GO:0009611 116 0.011
renal system development GO:0072001 94 0.011
cellular protein metabolic process GO:0044267 129 0.011
mitotic cytokinesis GO:0000281 3 0.011
protein homooligomerization GO:0051260 3 0.011
digestive tract development GO:0048565 265 0.011
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.011
organelle assembly GO:0070925 110 0.011
intracellular signal transduction GO:0035556 85 0.011
negative regulation of cytokine production GO:0001818 1 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.011
spermatid development GO:0007286 2 0.011
response to hexose GO:0009746 3 0.011
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.011
ear development GO:0043583 127 0.011
outflow tract morphogenesis GO:0003151 1 0.011
negative regulation of macromolecule metabolic process GO:0010605 76 0.011
axonogenesis GO:0007409 152 0.011
stem cell differentiation GO:0048863 117 0.011
regulation of dna replication GO:0006275 3 0.011
cilium assembly GO:0042384 58 0.011
protein targeting to membrane GO:0006612 1 0.011
response to biotic stimulus GO:0009607 97 0.011
golgi organization GO:0007030 1 0.011
organic substance transport GO:0071702 58 0.011
positive regulation of protein polymerization GO:0032273 2 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.011
multi organism process GO:0051704 134 0.011
kidney development GO:0001822 92 0.011
response to endogenous stimulus GO:0009719 83 0.011
endosome organization GO:0007032 2 0.011
meiotic chromosome segregation GO:0045132 3 0.011
purine nucleoside monophosphate catabolic process GO:0009128 4 0.011
membrane lipid biosynthetic process GO:0046467 2 0.011
atp catabolic process GO:0006200 4 0.011
peptidyl serine phosphorylation GO:0018105 1 0.011
regulation of nucleic acid templated transcription GO:1903506 213 0.010
single fertilization GO:0007338 3 0.010
regulation of protein complex disassembly GO:0043244 1 0.010
cellular response to radiation GO:0071478 4 0.010
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.010
positive regulation of stress activated mapk cascade GO:0032874 3 0.010
positive regulation of cell division GO:0051781 2 0.010
multi organism cellular process GO:0044764 2 0.010
negative regulation of multi organism process GO:0043901 3 0.010
nucleoside monophosphate catabolic process GO:0009125 4 0.010
synaptic vesicle transport GO:0048489 1 0.010
positive regulation of dna metabolic process GO:0051054 1 0.010
i kappab kinase nf kappab signaling GO:0007249 4 0.010
centrosome cycle GO:0007098 1 0.010
regulation of jak stat cascade GO:0046425 3 0.010
negative regulation of map kinase activity GO:0043407 2 0.010
regulation of blood vessel size GO:0050880 2 0.010
sensory perception of chemical stimulus GO:0007606 3 0.010
regulation of exocytosis GO:0017157 1 0.010
negative regulation of sequestering of calcium ion GO:0051283 4 0.010

xrcc4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.038
nervous system disease DOID:863 0 0.017
cardiovascular system disease DOID:1287 0 0.014
musculoskeletal system disease DOID:17 0 0.012
sensory system disease DOID:0050155 0 0.010