Danio rerio

5 known processes

xrcc6

X-ray repair complementing defective repair in Chinese hamster cells 6

(Aliases: zgc:64131,g22p1,wu:fi87b06)

xrcc6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
aging GO:0007568 2 0.383
glycoprotein metabolic process GO:0009100 23 0.246
regulation of multicellular organism growth GO:0040014 4 0.223
larval development GO:0002164 2 0.194
growth GO:0040007 174 0.188
tube morphogenesis GO:0035239 349 0.184
regulation of transcription dna templated GO:0006355 213 0.180
cellular macromolecule metabolic process GO:0044260 391 0.172
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.167
response to abiotic stimulus GO:0009628 122 0.157
macromolecule biosynthetic process GO:0009059 227 0.156
nucleic acid metabolic process GO:0090304 244 0.137
locomotion GO:0040011 313 0.137
cell part morphogenesis GO:0032990 246 0.136
positive regulation of transport GO:0051050 2 0.134
signal transduction GO:0007165 455 0.127
heart development GO:0007507 313 0.124
cellular nitrogen compound biosynthetic process GO:0044271 218 0.123
carbohydrate derivative metabolic process GO:1901135 61 0.113
mitotic dna damage checkpoint GO:0044773 4 0.113
regulation of nitrogen compound metabolic process GO:0051171 251 0.110
embryonic organ development GO:0048568 381 0.105
axon development GO:0061564 166 0.103
gene expression GO:0010467 252 0.102
cellular macromolecule biosynthetic process GO:0034645 224 0.101
nitrogen compound metabolic process GO:0006807 319 0.101
regulation of primary metabolic process GO:0080090 311 0.099
small molecule metabolic process GO:0044281 77 0.097
multicellular organism growth GO:0035264 4 0.097
regulation of macromolecule metabolic process GO:0060255 317 0.097
head development GO:0060322 303 0.094
heterocycle metabolic process GO:0046483 290 0.092
response to chemical GO:0042221 320 0.090
nucleic acid templated transcription GO:0097659 181 0.089
brain development GO:0007420 293 0.089
regulation of metabolic process GO:0019222 359 0.088
morphogenesis of an epithelium GO:0002009 333 0.083
cell projection morphogenesis GO:0048858 244 0.081
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.080
regulation of signaling GO:0023051 235 0.079
organelle organization GO:0006996 227 0.078
cell motility GO:0048870 244 0.077
embryonic organ morphogenesis GO:0048562 274 0.076
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.076
organic substance biosynthetic process GO:1901576 289 0.075
ameboidal type cell migration GO:0001667 143 0.074
organonitrogen compound metabolic process GO:1901564 74 0.074
phagocytosis engulfment GO:0006911 1 0.072
regulation of rna biosynthetic process GO:2001141 213 0.072
mitotic dna integrity checkpoint GO:0044774 4 0.069
response to light stimulus GO:0009416 46 0.069
peptidyl serine phosphorylation GO:0018105 1 0.068
single organism organelle organization GO:1902589 199 0.068
heterocycle biosynthetic process GO:0018130 215 0.068
regulation of biosynthetic process GO:0009889 250 0.068
synaptic growth at neuromuscular junction GO:0051124 2 0.067
g2 dna damage checkpoint GO:0031572 3 0.067
response to stress GO:0006950 263 0.064
blood vessel development GO:0001568 246 0.064
nucleobase containing compound metabolic process GO:0006139 274 0.063
regulation of gene expression GO:0010468 265 0.062
cellular biosynthetic process GO:0044249 286 0.061
negative regulation of biological process GO:0048519 304 0.061
cellular nitrogen compound metabolic process GO:0034641 290 0.060
specification of symmetry GO:0009799 204 0.059
cell cycle g1 s phase transition GO:0044843 1 0.058
regulation of rna metabolic process GO:0051252 224 0.058
mitotic g2 dna damage checkpoint GO:0007095 3 0.058
regulation of multicellular organismal process GO:0051239 277 0.058
digestive system development GO:0055123 289 0.057
erk1 and erk2 cascade GO:0070371 4 0.057
response to radiation GO:0009314 51 0.056
aromatic compound biosynthetic process GO:0019438 217 0.055
organic cyclic compound biosynthetic process GO:1901362 223 0.054
regulation of cellular biosynthetic process GO:0031326 245 0.053
sensory organ development GO:0007423 393 0.052
regulation of signal transduction GO:0009966 225 0.052
cellular aromatic compound metabolic process GO:0006725 295 0.052
regulation of cellular metabolic process GO:0031323 320 0.051
membrane invagination GO:0010324 1 0.051
meiotic nuclear division GO:0007126 4 0.051
single organism metabolic process GO:0044710 217 0.050
gastrulation GO:0007369 208 0.049
positive regulation of secretion by cell GO:1903532 1 0.049
mitotic g2 m transition checkpoint GO:0044818 3 0.049
cell migration GO:0016477 237 0.048
nuclear migration GO:0007097 3 0.048
cell projection organization GO:0030030 284 0.048
regulation of synapse organization GO:0050807 3 0.047
transcription dna templated GO:0006351 181 0.047
phagocytosis GO:0006909 3 0.046
response to organic substance GO:0010033 153 0.046
positive regulation of biological process GO:0048518 253 0.046
developmental growth GO:0048589 166 0.046
determination of bilateral symmetry GO:0009855 204 0.046
muscle cell development GO:0055001 115 0.045
vasculature development GO:0001944 278 0.045
regulation of metal ion transport GO:0010959 4 0.045
sensory organ morphogenesis GO:0090596 200 0.044
nucleoside monophosphate catabolic process GO:0009125 4 0.044
regulation of cell communication GO:0010646 232 0.044
regulation of cell shape GO:0008360 1 0.044
adult behavior GO:0030534 2 0.043
organic substance transport GO:0071702 58 0.043
enzyme linked receptor protein signaling pathway GO:0007167 106 0.043
protein import GO:0017038 3 0.043
regulation of developmental process GO:0050793 247 0.042
oxoacid metabolic process GO:0043436 31 0.041
stem cell proliferation GO:0072089 4 0.041
body morphogenesis GO:0010171 16 0.041
behavior GO:0007610 74 0.040
organic cyclic compound metabolic process GO:1901360 301 0.040
regulation of response to stimulus GO:0048583 269 0.040
rna metabolic process GO:0016070 219 0.040
regulation of protein transport GO:0051223 3 0.039
rna biosynthetic process GO:0032774 181 0.039
cellular component assembly GO:0022607 170 0.038
transcription from rna polymerase ii promoter GO:0006366 80 0.038
modification dependent macromolecule catabolic process GO:0043632 3 0.038
cell morphogenesis involved in differentiation GO:0000904 195 0.037
positive regulation of catabolic process GO:0009896 4 0.037
nucleobase containing compound biosynthetic process GO:0034654 205 0.037
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.037
protein localization to nucleus GO:0034504 3 0.037
neuron projection morphogenesis GO:0048812 161 0.037
cellular response to organic substance GO:0071310 105 0.036
cellular protein catabolic process GO:0044257 4 0.036
mitotic cell cycle embryonic GO:0045448 2 0.035
positive regulation of nervous system development GO:0051962 25 0.035
stem cell maintenance GO:0019827 4 0.035
carbohydrate derivative biosynthetic process GO:1901137 43 0.035
cell projection assembly GO:0030031 64 0.035
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.035
atp catabolic process GO:0006200 4 0.035
regulation of cytokine production GO:0001817 3 0.035
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.035
cell morphogenesis GO:0000902 289 0.034
digestive tract development GO:0048565 265 0.034
generation of neurons GO:0048699 385 0.034
purine nucleoside monophosphate catabolic process GO:0009128 4 0.034
microtubule based movement GO:0007018 33 0.034
peptidyl serine modification GO:0018209 2 0.034
response to endogenous stimulus GO:0009719 83 0.034
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.034
gtp catabolic process GO:0006184 2 0.033
dna damage checkpoint GO:0000077 6 0.033
ribose phosphate metabolic process GO:0019693 27 0.033
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.032
regulation of establishment of protein localization GO:0070201 4 0.032
positive regulation of secretion GO:0051047 1 0.032
ear development GO:0043583 127 0.031
regulation of macromolecule biosynthetic process GO:0010556 225 0.031
pronuclear migration GO:0035046 1 0.031
heart morphogenesis GO:0003007 156 0.031
regulation of purine nucleotide catabolic process GO:0033121 2 0.030
ribonucleoside monophosphate catabolic process GO:0009158 4 0.030
central nervous system development GO:0007417 387 0.030
maintenance of location GO:0051235 4 0.030
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.029
cell fate commitment GO:0045165 99 0.029
response to lipid GO:0033993 60 0.029
regulation of nucleoside metabolic process GO:0009118 2 0.029
meiotic cell cycle process GO:1903046 3 0.028
microtubule based process GO:0007017 60 0.028
axonogenesis GO:0007409 152 0.028
gtp metabolic process GO:0046039 4 0.028
digestive tract morphogenesis GO:0048546 231 0.028
establishment of protein localization to organelle GO:0072594 4 0.028
cilium assembly GO:0042384 58 0.028
positive regulation of cellular catabolic process GO:0031331 3 0.028
regulation of protein localization to nucleus GO:1900180 2 0.028
nuclear import GO:0051170 3 0.028
regulation of synapse assembly GO:0051963 3 0.027
epithelial tube morphogenesis GO:0060562 148 0.027
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.027
positive regulation of cellular process GO:0048522 201 0.027
single organism behavior GO:0044708 24 0.027
small gtpase mediated signal transduction GO:0007264 8 0.027
modification dependent protein catabolic process GO:0019941 3 0.026
response to uv GO:0009411 3 0.026
regulation of erk1 and erk2 cascade GO:0070372 4 0.026
cellular component movement GO:0006928 335 0.026
cytokinesis GO:0000910 3 0.025
cellular component biogenesis GO:0044085 178 0.025
blood vessel morphogenesis GO:0048514 216 0.025
positive regulation of metabolic process GO:0009893 108 0.025
mitotic cell cycle process GO:1903047 48 0.025
regulation of nucleotide catabolic process GO:0030811 2 0.025
protein metabolic process GO:0019538 183 0.025
g1 s transition of mitotic cell cycle GO:0000082 1 0.025
stem cell fate commitment GO:0048865 1 0.025
neuron development GO:0048666 262 0.025
taxis GO:0042330 109 0.025
cellular response to dna damage stimulus GO:0006974 24 0.024
hemopoiesis GO:0030097 183 0.024
response to external stimulus GO:0009605 264 0.024
positive regulation of cellular metabolic process GO:0031325 94 0.024
ubiquitin dependent protein catabolic process GO:0006511 3 0.024
lipid storage GO:0019915 1 0.024
gamete generation GO:0007276 33 0.024
establishment of localization GO:0051234 244 0.024
biosynthetic process GO:0009058 294 0.024
nuclear transport GO:0051169 4 0.024
neuroblast proliferation GO:0007405 2 0.023
dna integrity checkpoint GO:0031570 6 0.023
negative regulation of gene expression GO:0010629 65 0.023
peptide transport GO:0015833 1 0.023
determination of left right symmetry GO:0007368 179 0.023
response to alkaloid GO:0043279 2 0.023
regulation of localization GO:0032879 104 0.023
regulation of apoptotic process GO:0042981 98 0.023
regulation of cellular amine metabolic process GO:0033238 0 0.023
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.023
regulation of axonogenesis GO:0050770 32 0.023
embryo development ending in birth or egg hatching GO:0009792 271 0.022
transmembrane transport GO:0055085 120 0.022
golgi vesicle transport GO:0048193 3 0.022
camera type eye development GO:0043010 222 0.022
fertilization GO:0009566 3 0.022
cognition GO:0050890 1 0.022
ribonucleotide metabolic process GO:0009259 27 0.022
nucleoside phosphate metabolic process GO:0006753 28 0.022
striated muscle cell development GO:0055002 108 0.022
organic acid metabolic process GO:0006082 31 0.022
positive regulation of ras protein signal transduction GO:0046579 1 0.022
localization of cell GO:0051674 244 0.021
nucleocytoplasmic transport GO:0006913 4 0.021
cell cycle GO:0007049 93 0.021
phosphate containing compound metabolic process GO:0006796 108 0.021
negative regulation of macromolecule metabolic process GO:0010605 76 0.021
amine metabolic process GO:0009308 2 0.021
regulation of intracellular protein transport GO:0033157 3 0.021
system process GO:0003008 185 0.021
cortical actin cytoskeleton organization GO:0030866 1 0.021
neuron projection development GO:0031175 180 0.021
protein import into nucleus GO:0006606 3 0.021
protein targeting to nucleus GO:0044744 3 0.021
regulation of canonical wnt signaling pathway GO:0060828 34 0.020
locomotory behavior GO:0007626 34 0.020
canonical wnt signaling pathway GO:0060070 48 0.020
response to steroid hormone GO:0048545 35 0.020
regulation of neuron differentiation GO:0045664 56 0.020
regulation of gtp catabolic process GO:0033124 2 0.020
chromosome organization GO:0051276 31 0.020
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.020
regulation of nucleic acid templated transcription GO:1903506 213 0.020
multi organism process GO:0051704 134 0.019
regulation of growth GO:0040008 42 0.019
ras protein signal transduction GO:0007265 7 0.019
negative regulation of cell communication GO:0010648 96 0.019
cellular component morphogenesis GO:0032989 336 0.019
regulation of neural precursor cell proliferation GO:2000177 3 0.019
thermosensory behavior GO:0040040 1 0.019
regulation of dna replication GO:0006275 3 0.019
regulation of neurogenesis GO:0050767 87 0.019
purine containing compound metabolic process GO:0072521 29 0.019
dna metabolic process GO:0006259 27 0.019
positive regulation of cell cycle GO:0045787 3 0.019
regulation of organelle organization GO:0033043 29 0.019
response to nutrient GO:0007584 3 0.018
regulation of cytoplasmic transport GO:1903649 4 0.018
positive regulation of nucleoside metabolic process GO:0045979 1 0.018
glial cell migration GO:0008347 3 0.018
positive regulation of gtpase activity GO:0043547 1 0.018
carboxylic acid metabolic process GO:0019752 22 0.018
actin filament polymerization GO:0030041 2 0.018
wound healing GO:0042060 90 0.018
embryonic heart tube morphogenesis GO:0003143 108 0.018
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.018
stem cell differentiation GO:0048863 117 0.018
guanosine containing compound metabolic process GO:1901068 4 0.018
cytoskeleton dependent cytokinesis GO:0061640 3 0.018
regulation of developmental growth GO:0048638 38 0.018
developmental process involved in reproduction GO:0003006 27 0.018
epiboly GO:0090504 41 0.018
regulation of cell death GO:0010941 103 0.018
purine nucleotide metabolic process GO:0006163 27 0.018
response to oxygen containing compound GO:1901700 55 0.018
wnt signaling pathway GO:0016055 80 0.017
mesenchymal cell differentiation GO:0048762 87 0.017
death GO:0016265 121 0.017
homeostatic process GO:0042592 142 0.017
protein stabilization GO:0050821 2 0.017
purine ribonucleotide metabolic process GO:0009150 27 0.017
cellular localization GO:0051641 97 0.017
regulation of wnt signaling pathway GO:0030111 53 0.017
sensory perception GO:0007600 39 0.017
mitotic cell cycle GO:0000278 64 0.017
developmental growth involved in morphogenesis GO:0060560 86 0.017
otolith development GO:0048840 32 0.017
cell cycle checkpoint GO:0000075 7 0.017
neuroblast fate commitment GO:0014017 1 0.017
positive regulation of signaling GO:0023056 56 0.017
guanosine containing compound catabolic process GO:1901069 2 0.017
eye development GO:0001654 277 0.017
chemosensory behavior GO:0007635 1 0.016
apoptotic process GO:0006915 116 0.016
determination of heart left right asymmetry GO:0061371 117 0.016
neurological system process GO:0050877 62 0.016
regulation of gtpase activity GO:0043087 2 0.016
regulation of meiotic cell cycle GO:0051445 1 0.016
b cell activation GO:0042113 2 0.016
skeletal muscle tissue development GO:0007519 67 0.016
positive regulation of neuron projection development GO:0010976 9 0.016
single organism nuclear import GO:1902593 3 0.016
chromosome segregation GO:0007059 12 0.016
regulation of stem cell differentiation GO:2000736 4 0.015
cellular protein metabolic process GO:0044267 129 0.015
regulation of wound healing GO:0061041 2 0.015
axon guidance GO:0007411 86 0.015
neural crest cell differentiation GO:0014033 72 0.015
organelle assembly GO:0070925 110 0.015
cell cycle g2 m phase transition GO:0044839 4 0.015
response to mechanical stimulus GO:0009612 24 0.015
regulation of protein import into nucleus GO:0042306 2 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
nuclear division GO:0000280 23 0.015
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.015
positive regulation of cytokine production GO:0001819 2 0.015
immune system process GO:0002376 241 0.015
cellular response to extracellular stimulus GO:0031668 2 0.015
protein complex disassembly GO:0043241 1 0.015
g2 m transition of mitotic cell cycle GO:0000086 4 0.015
single organism localization GO:1902578 225 0.014
cellular component disassembly GO:0022411 1 0.014
homeostasis of number of cells GO:0048872 62 0.014
epithelial cell development GO:0002064 42 0.014
neuromuscular junction development GO:0007528 9 0.014
organelle localization GO:0051640 49 0.014
cellular catabolic process GO:0044248 27 0.014
cellular response to chemical stimulus GO:0070887 157 0.014
negative regulation of programmed cell death GO:0043069 58 0.014
cytokinetic process GO:0032506 2 0.014
macromolecular complex subunit organization GO:0043933 74 0.014
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.014
positive regulation of neurogenesis GO:0050769 24 0.014
forebrain development GO:0030900 96 0.014
positive regulation of multicellular organismal process GO:0051240 52 0.014
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.014
cell fate specification GO:0001708 68 0.014
regulation of mitotic cell cycle GO:0007346 25 0.014
regulation of exocytosis GO:0017157 1 0.014
nuclear export GO:0051168 1 0.013
establishment of spindle localization GO:0051293 12 0.013
muscle organ development GO:0007517 101 0.013
nucleobase containing small molecule metabolic process GO:0055086 32 0.013
negative regulation of cell death GO:0060548 60 0.013
embryonic pattern specification GO:0009880 44 0.013
establishment of localization in cell GO:0051649 77 0.013
cellular protein modification process GO:0006464 100 0.013
neuron differentiation GO:0030182 353 0.013
response to vitamin GO:0033273 3 0.013
proteasomal protein catabolic process GO:0010498 2 0.013
positive regulation of developmental process GO:0051094 50 0.013
positive regulation of cellular component biogenesis GO:0044089 3 0.013
double strand break repair GO:0006302 3 0.013
amino acid transport GO:0006865 2 0.013
regulation of immune system process GO:0002682 34 0.013
regulation of binding GO:0051098 3 0.013
negative regulation of metabolic process GO:0009892 86 0.013
cellular amine metabolic process GO:0044106 2 0.013
mitotic cell cycle phase transition GO:0044772 9 0.013
establishment of organelle localization GO:0051656 45 0.013
histone phosphorylation GO:0016572 2 0.012
negative regulation of signal transduction GO:0009968 94 0.012
muscle fiber development GO:0048747 52 0.012
regulation of phosphorus metabolic process GO:0051174 43 0.012
programmed cell death GO:0012501 119 0.012
protein dephosphorylation GO:0006470 3 0.012
renal system development GO:0072001 94 0.012
er to golgi vesicle mediated transport GO:0006888 1 0.012
negative regulation of biosynthetic process GO:0009890 55 0.012
regulation of protein polymerization GO:0032271 2 0.012
regulation of programmed cell death GO:0043067 101 0.012
sulfur compound biosynthetic process GO:0044272 9 0.012
anterior posterior pattern specification GO:0009952 152 0.012
regulation of nucleocytoplasmic transport GO:0046822 2 0.012
neuromuscular synaptic transmission GO:0007274 2 0.012
single organism biosynthetic process GO:0044711 71 0.012
response to wounding GO:0009611 116 0.012
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.011
response to hormone GO:0009725 48 0.011
connective tissue development GO:0061448 99 0.011
single organism transport GO:0044765 206 0.011
multicellular organism reproduction GO:0032504 35 0.011
transport GO:0006810 220 0.011
cell cycle process GO:0022402 53 0.011
cellular ketone metabolic process GO:0042180 11 0.011
positive regulation of nucleotide catabolic process GO:0030813 1 0.011
phosphorylation GO:0016310 69 0.011
meiosis i GO:0007127 1 0.011
actin cytoskeleton organization GO:0030036 63 0.011
regulation of protein binding GO:0043393 3 0.011
regulation of cell projection organization GO:0031344 44 0.011
regulation of chromosome segregation GO:0051983 1 0.011
muscle structure development GO:0061061 196 0.011
embryonic limb morphogenesis GO:0030326 2 0.011
response to temperature stimulus GO:0009266 15 0.011
inner ear development GO:0048839 126 0.011
positive regulation of gtp catabolic process GO:0033126 1 0.011
negative regulation of apoptotic process GO:0043066 55 0.011
response to ketone GO:1901654 1 0.011
cellular response to steroid hormone stimulus GO:0071383 31 0.011
regulation of cellular component organization GO:0051128 86 0.011
nephron morphogenesis GO:0072028 2 0.011
regulation of filopodium assembly GO:0051489 2 0.011
striated muscle tissue development GO:0014706 110 0.011
regulation of protein complex assembly GO:0043254 3 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
cellular response to external stimulus GO:0071496 2 0.010
specification of axis polarity GO:0065001 4 0.010
negative regulation of cytokine production GO:0001818 1 0.010
negative regulation of cellular process GO:0048523 283 0.010
single organism cellular localization GO:1902580 46 0.010
morphogenesis of an epithelial sheet GO:0002011 49 0.010
macromolecule modification GO:0043412 111 0.010
protein modification process GO:0036211 100 0.010
actin filament based movement GO:0030048 1 0.010
mitotic nuclear division GO:0007067 18 0.010
glycoprotein biosynthetic process GO:0009101 21 0.010
protein complex subunit organization GO:0071822 46 0.010
positive regulation of nucleic acid templated transcription GO:1903508 57 0.010

xrcc6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.020
disease of cellular proliferation DOID:14566 0 0.020
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.017
organ system cancer DOID:0050686 0 0.016