Danio rerio

0 known processes

gulp1

GULP, engulfment adaptor PTB domain containing 1

(Aliases: fj61e02,CED-6,MGC123057,si:by35d8.1,si:xx-35d8.1,wu:fj61e02)

gulp1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
endosomal transport GO:0016197 2 0.328
nitrogen compound metabolic process GO:0006807 319 0.155
cellular macromolecule metabolic process GO:0044260 391 0.153
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.147
regulation of cellular metabolic process GO:0031323 320 0.134
membrane lipid biosynthetic process GO:0046467 2 0.127
regulation of primary metabolic process GO:0080090 311 0.123
single organism transport GO:0044765 206 0.114
aromatic compound biosynthetic process GO:0019438 217 0.111
single organism localization GO:1902578 225 0.103
response to chemical GO:0042221 320 0.091
organic cyclic compound metabolic process GO:1901360 301 0.087
cellular nitrogen compound metabolic process GO:0034641 290 0.085
larval development GO:0002164 2 0.085
regulation of metabolic process GO:0019222 359 0.083
transport GO:0006810 220 0.080
cellular component movement GO:0006928 335 0.079
blood vessel development GO:0001568 246 0.075
regulation of response to stimulus GO:0048583 269 0.074
Zebrafish
multicellular organismal metabolic process GO:0044236 2 0.074
generation of neurons GO:0048699 385 0.071
stem cell proliferation GO:0072089 4 0.066
central nervous system development GO:0007417 387 0.065
positive regulation of biological process GO:0048518 253 0.063
response to stress GO:0006950 263 0.063
macromolecule biosynthetic process GO:0009059 227 0.062
immune system process GO:0002376 241 0.062
Zebrafish
response to glucose GO:0009749 3 0.061
nucleobase containing compound metabolic process GO:0006139 274 0.061
response to carbohydrate GO:0009743 3 0.060
regulation of rna biosynthetic process GO:2001141 213 0.058
cellular macromolecule biosynthetic process GO:0034645 224 0.058
regulation of cellular biosynthetic process GO:0031326 245 0.057
response to monosaccharide GO:0034284 3 0.056
response to hexose GO:0009746 3 0.056
positive regulation of catabolic process GO:0009896 4 0.054
establishment of localization GO:0051234 244 0.052
protein metabolic process GO:0019538 183 0.051
regulation of multicellular organismal process GO:0051239 277 0.051
single organism metabolic process GO:0044710 217 0.050
golgi vesicle transport GO:0048193 3 0.050
response to external stimulus GO:0009605 264 0.049
negative regulation of cellular process GO:0048523 283 0.048
Zebrafish
vasculature development GO:0001944 278 0.048
Zebrafish
phagocytosis GO:0006909 3 0.047
chordate embryonic development GO:0043009 271 0.047
gene expression GO:0010467 252 0.046
gastrulation GO:0007369 208 0.046
regulation of signaling GO:0023051 235 0.046
Zebrafish
regulation of nitrogen compound metabolic process GO:0051171 251 0.045
rna metabolic process GO:0016070 219 0.045
nucleobase containing compound biosynthetic process GO:0034654 205 0.045
heterocycle metabolic process GO:0046483 290 0.044
positive regulation of metabolic process GO:0009893 108 0.044
cellular aromatic compound metabolic process GO:0006725 295 0.044
autophagy GO:0006914 4 0.043
cellular localization GO:0051641 97 0.043
organonitrogen compound metabolic process GO:1901564 74 0.041
regulation of cellular amino acid metabolic process GO:0006521 0 0.041
regulation of cellular amine metabolic process GO:0033238 0 0.040
organic acid metabolic process GO:0006082 31 0.038
positive regulation of signaling GO:0023056 56 0.038
regulation of multicellular organism growth GO:0040014 4 0.038
small molecule metabolic process GO:0044281 77 0.038
heterocycle biosynthetic process GO:0018130 215 0.037
enzyme linked receptor protein signaling pathway GO:0007167 106 0.037
organic substance biosynthetic process GO:1901576 289 0.036
regulation of multicellular organismal development GO:2000026 223 0.036
embryonic organ development GO:0048568 381 0.035
Zebrafish
negative regulation of cell communication GO:0010648 96 0.034
Zebrafish
connective tissue development GO:0061448 99 0.034
multicellular organismal macromolecule metabolic process GO:0044259 2 0.034
nuclear migration GO:0007097 3 0.034
convergent extension GO:0060026 118 0.033
regulation of biosynthetic process GO:0009889 250 0.033
carboxylic acid metabolic process GO:0019752 22 0.033
organic cyclic compound biosynthetic process GO:1901362 223 0.033
blood vessel morphogenesis GO:0048514 216 0.032
response to organic substance GO:0010033 153 0.032
cellular response to nutrient levels GO:0031669 2 0.032
cellular ketone metabolic process GO:0042180 11 0.031
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.031
cellular response to chemical stimulus GO:0070887 157 0.031
digestive system development GO:0055123 289 0.031
regulation of gene expression GO:0010468 265 0.031
embryo development ending in birth or egg hatching GO:0009792 271 0.031
purine ribonucleotide metabolic process GO:0009150 27 0.030
camera type eye development GO:0043010 222 0.030
oxoacid metabolic process GO:0043436 31 0.030
eye morphogenesis GO:0048592 144 0.030
cellular amine metabolic process GO:0044106 2 0.029
cellular response to organic substance GO:0071310 105 0.029
sphingolipid biosynthetic process GO:0030148 2 0.029
nucleic acid metabolic process GO:0090304 244 0.028
meiotic nuclear division GO:0007126 4 0.028
transcription from rna polymerase ii promoter GO:0006366 80 0.028
nucleobase containing small molecule metabolic process GO:0055086 32 0.028
cellular amino acid metabolic process GO:0006520 7 0.028
regulation of molecular function GO:0065009 70 0.028
establishment of organelle localization GO:0051656 45 0.028
amine metabolic process GO:0009308 2 0.028
single organism organelle organization GO:1902589 199 0.028
positive regulation of cellular process GO:0048522 201 0.027
regulation of cellular ketone metabolic process GO:0010565 7 0.027
negative regulation of protein localization to nucleus GO:1900181 2 0.027
cell proliferation GO:0008283 80 0.027
establishment of localization in cell GO:0051649 77 0.026
release of sequestered calcium ion into cytosol GO:0051209 3 0.026
positive regulation of cellular amine metabolic process GO:0033240 0 0.026
negative regulation of multicellular organismal process GO:0051241 69 0.026
positive regulation of cellular component biogenesis GO:0044089 3 0.026
multicellular organism growth GO:0035264 4 0.026
protein localization to plasma membrane GO:0072659 1 0.026
cell substrate adhesion GO:0031589 4 0.026
single organism cellular localization GO:1902580 46 0.026
negative regulation of protein phosphorylation GO:0001933 4 0.025
ribonucleotide metabolic process GO:0009259 27 0.025
regulation of macromolecule biosynthetic process GO:0010556 225 0.025
cell migration GO:0016477 237 0.024
establishment of protein localization to organelle GO:0072594 4 0.024
guanosine containing compound catabolic process GO:1901069 2 0.024
regulation of purine nucleotide metabolic process GO:1900542 17 0.024
head development GO:0060322 303 0.023
ameboidal type cell migration GO:0001667 143 0.023
regulation of cell communication GO:0010646 232 0.023
Zebrafish
cellular amide metabolic process GO:0043603 4 0.023
regulation of transcription dna templated GO:0006355 213 0.023
maintenance of location GO:0051235 4 0.022
guanosine containing compound metabolic process GO:1901068 4 0.022
regulation of signal transduction GO:0009966 225 0.022
Zebrafish
regulation of nucleoside metabolic process GO:0009118 2 0.022
transcription dna templated GO:0006351 181 0.022
angiogenesis GO:0001525 158 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.022
regulation of cell activation GO:0050865 1 0.021
positive regulation of transport GO:0051050 2 0.021
gtp catabolic process GO:0006184 2 0.021
cartilage development GO:0051216 96 0.021
regulation of hormone secretion GO:0046883 2 0.021
response to food GO:0032094 1 0.021
regulation of reproductive process GO:2000241 4 0.021
sensory organ development GO:0007423 393 0.021
medulla oblongata development GO:0021550 4 0.020
post golgi vesicle mediated transport GO:0006892 1 0.020
regulation of macromolecule metabolic process GO:0060255 317 0.020
regulation of nucleic acid templated transcription GO:1903506 213 0.020
cellular protein metabolic process GO:0044267 129 0.020
phosphorus metabolic process GO:0006793 109 0.020
cyclic nucleotide metabolic process GO:0009187 18 0.020
single organism membrane organization GO:0044802 20 0.020
regulation of rna metabolic process GO:0051252 224 0.020
eye development GO:0001654 277 0.019
regulation of transporter activity GO:0032409 2 0.019
meiotic cell cycle process GO:1903046 3 0.019
positive regulation of cellular catabolic process GO:0031331 3 0.019
stem cell division GO:0017145 1 0.019
digestive tract mesoderm development GO:0007502 1 0.019
membrane organization GO:0061024 21 0.019
purine containing compound metabolic process GO:0072521 29 0.019
regulation of blood pressure GO:0008217 1 0.019
inositol lipid mediated signaling GO:0048017 2 0.019
brain development GO:0007420 293 0.019
phosphatidylinositol mediated signaling GO:0048015 2 0.019
negative regulation of endopeptidase activity GO:0010951 10 0.019
wound healing GO:0042060 90 0.019
cell surface receptor signaling pathway GO:0007166 325 0.019
Zebrafish
cell motility GO:0048870 244 0.019
cell death GO:0008219 121 0.019
positive regulation of signal transduction GO:0009967 56 0.018
aging GO:0007568 2 0.018
hormone secretion GO:0046879 2 0.018
biosynthetic process GO:0009058 294 0.018
collagen metabolic process GO:0032963 2 0.018
cytoskeleton organization GO:0007010 96 0.018
taxis GO:0042330 109 0.018
extracellular matrix organization GO:0030198 27 0.018
programmed cell death GO:0012501 119 0.018
mononuclear cell proliferation GO:0032943 1 0.018
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.018
localization of cell GO:0051674 244 0.018
morphogenesis of an epithelium GO:0002009 333 0.018
cell chemotaxis GO:0060326 17 0.018
organophosphate metabolic process GO:0019637 37 0.018
regulation of purine nucleotide catabolic process GO:0033121 2 0.018
membrane fusion GO:0061025 2 0.018
neuron differentiation GO:0030182 353 0.018
organelle organization GO:0006996 227 0.017
regulation of binding GO:0051098 3 0.017
regeneration GO:0031099 91 0.017
cell cycle process GO:0022402 53 0.017
regulation of cell differentiation GO:0045595 142 0.017
locomotion GO:0040011 313 0.017
membrane invagination GO:0010324 1 0.017
regulation of vasculature development GO:1901342 33 0.017
cellular response to external stimulus GO:0071496 2 0.017
mitochondrion organization GO:0007005 4 0.017
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.017
negative regulation of metabolic process GO:0009892 86 0.017
negative regulation of signal transduction GO:0009968 94 0.016
Zebrafish
cellular nitrogen compound biosynthetic process GO:0044271 218 0.016
regulation of lyase activity GO:0051339 12 0.016
organelle localization GO:0051640 49 0.016
exocytosis GO:0006887 1 0.016
regulation of systemic arterial blood pressure GO:0003073 1 0.016
camera type eye morphogenesis GO:0048593 108 0.016
regulation of cytoplasmic transport GO:1903649 4 0.016
skeletal system development GO:0001501 181 0.016
negative regulation of sequestering of calcium ion GO:0051283 4 0.016
response to wounding GO:0009611 116 0.016
lateral line system development GO:0048925 76 0.015
regulation of developmental process GO:0050793 247 0.015
cellular protein catabolic process GO:0044257 4 0.015
atp catabolic process GO:0006200 4 0.015
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.015
regulation of endothelial cell proliferation GO:0001936 1 0.015
regulation of epithelial cell proliferation GO:0050678 3 0.015
carbohydrate derivative metabolic process GO:1901135 61 0.015
organelle fusion GO:0048284 3 0.015
regulation of cellular protein metabolic process GO:0032268 52 0.015
neuroblast proliferation GO:0007405 2 0.015
nucleoside monophosphate catabolic process GO:0009125 4 0.015
lymphocyte proliferation GO:0046651 1 0.015
signal transduction GO:0007165 455 0.014
Zebrafish
carbohydrate homeostasis GO:0033500 1 0.014
calcium mediated signaling GO:0019722 2 0.014
gtp metabolic process GO:0046039 4 0.014
multicellular organismal response to stress GO:0033555 2 0.014
rna biosynthetic process GO:0032774 181 0.014
peptidyl threonine modification GO:0018210 1 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.014
regulation of nucleotide catabolic process GO:0030811 2 0.014
peptide transport GO:0015833 1 0.014
system process GO:0003008 185 0.014
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.014
protein modification process GO:0036211 100 0.014
embryonic skeletal system development GO:0048706 97 0.013
positive regulation of secretion GO:0051047 1 0.013
production of molecular mediator of immune response GO:0002440 2 0.013
immune system development GO:0002520 191 0.013
Zebrafish
negative regulation of signaling GO:0023057 96 0.013
Zebrafish
peptidyl threonine phosphorylation GO:0018107 1 0.013
regulation of cell motility GO:2000145 46 0.013
positive regulation of protein complex assembly GO:0031334 2 0.013
embryonic heart tube development GO:0035050 133 0.013
actin cytoskeleton organization GO:0030036 63 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.013
embryonic organ morphogenesis GO:0048562 274 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.013
glucose import GO:0046323 2 0.013
positive regulation of cellular metabolic process GO:0031325 94 0.013
regulation of cellular response to growth factor stimulus GO:0090287 35 0.013
negative regulation of response to stimulus GO:0048585 104 0.013
Zebrafish
regulation of establishment of protein localization GO:0070201 4 0.013
protein dephosphorylation GO:0006470 3 0.013
cellular response to oxygen containing compound GO:1901701 20 0.013
intracellular signal transduction GO:0035556 85 0.013
lipid storage GO:0019915 1 0.013
muscle fiber development GO:0048747 52 0.012
positive regulation of glucose import GO:0046326 1 0.012
mitotic cell cycle process GO:1903047 48 0.012
tube morphogenesis GO:0035239 349 0.012
sprouting angiogenesis GO:0002040 53 0.012
cell cycle g1 s phase transition GO:0044843 1 0.012
zymogen activation GO:0031638 3 0.012
regulation of nucleotide metabolic process GO:0006140 17 0.012
negative regulation of defense response GO:0031348 2 0.012
cell aging GO:0007569 2 0.012
response to abiotic stimulus GO:0009628 122 0.012
response to amino acid GO:0043200 2 0.012
positive regulation of cellular biosynthetic process GO:0031328 68 0.012
regulation of wound healing GO:0061041 2 0.012
stem cell differentiation GO:0048863 117 0.012
retina development in camera type eye GO:0060041 146 0.012
death GO:0016265 121 0.012
intracellular transport GO:0046907 32 0.012
regulation of response to biotic stimulus GO:0002831 2 0.012
regulation of gtp catabolic process GO:0033124 2 0.012
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.012
dicarboxylic acid metabolic process GO:0043648 1 0.012
positive regulation of gliogenesis GO:0014015 2 0.012
macromolecule modification GO:0043412 111 0.011
regulation of protein polymerization GO:0032271 2 0.011
regulation of catalytic activity GO:0050790 55 0.011
protein localization to nucleus GO:0034504 3 0.011
cellular response to endogenous stimulus GO:0071495 68 0.011
cellular protein localization GO:0034613 20 0.011
ribonucleoside monophosphate catabolic process GO:0009158 4 0.011
regulation of localization GO:0032879 104 0.011
cellular biosynthetic process GO:0044249 286 0.011
nucleic acid templated transcription GO:0097659 181 0.011
cellular component biogenesis GO:0044085 178 0.011
multicellular organismal signaling GO:0035637 22 0.011
negative regulation of biological process GO:0048519 304 0.011
Zebrafish
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.011
establishment or maintenance of polarity of embryonic epithelium GO:0016332 2 0.011
regulation of gtpase activity GO:0043087 2 0.011
glial cell differentiation GO:0010001 42 0.011
regulation of angiogenesis GO:0045765 26 0.011
negative regulation of epithelial cell proliferation GO:0050680 1 0.011
ion transport GO:0006811 114 0.011
regulation of stem cell proliferation GO:0072091 2 0.011
digestive tract morphogenesis GO:0048546 231 0.011
cellular response to extracellular stimulus GO:0031668 2 0.011
proteolysis GO:0006508 38 0.011
skeletal system morphogenesis GO:0048705 102 0.011
regulation of cell death GO:0010941 103 0.011
glucose homeostasis GO:0042593 1 0.011
glycolipid metabolic process GO:0006664 8 0.011
embryonic hemopoiesis GO:0035162 53 0.011
Zebrafish
positive regulation of nucleotide catabolic process GO:0030813 1 0.011
behavior GO:0007610 74 0.011
chemotaxis GO:0006935 104 0.011
establishment of synaptic vesicle localization GO:0097480 1 0.011
response to endogenous stimulus GO:0009719 83 0.011
positive regulation of rna metabolic process GO:0051254 59 0.011
regulation of phosphate metabolic process GO:0019220 43 0.011
negative regulation of cellular metabolic process GO:0031324 77 0.011
positive regulation of nucleoside metabolic process GO:0045979 1 0.011
regulation of intracellular protein transport GO:0033157 3 0.011
purine ribonucleotide biosynthetic process GO:0009152 20 0.011
positive regulation of gtpase activity GO:0043547 1 0.011
regulation of chondrocyte differentiation GO:0032330 1 0.010
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.010
protein stabilization GO:0050821 2 0.010
regulation of protein complex assembly GO:0043254 3 0.010
dorsal motor nucleus of vagus nerve development GO:0021744 4 0.010
muscle organ development GO:0007517 101 0.010
retina morphogenesis in camera type eye GO:0060042 79 0.010
regulation of blood vessel size GO:0050880 2 0.010
regulation of erk1 and erk2 cascade GO:0070372 4 0.010
transmembrane transport GO:0055085 120 0.010

gulp1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.072
immune system disease DOID:2914 0 0.047
nervous system disease DOID:863 0 0.025
musculoskeletal system disease DOID:17 0 0.017
sensory system disease DOID:0050155 0 0.015
eye and adnexa disease DOID:1492 0 0.015
eye disease DOID:5614 0 0.015