Danio rerio

0 known processes

zgc:92806

zgc:92806

zgc:92806 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.223
regulation of developmental process GO:0050793 247 0.172
cellular nitrogen compound metabolic process GO:0034641 290 0.161
regulation of biological quality GO:0065008 263 0.150
regulation of cellular metabolic process GO:0031323 320 0.139
negative regulation of cellular process GO:0048523 283 0.136
negative regulation of response to stimulus GO:0048585 104 0.134
organelle organization GO:0006996 227 0.123
phagocytosis GO:0006909 3 0.122
regulation of multicellular organismal process GO:0051239 277 0.108
locomotion GO:0040011 313 0.105
multi organism process GO:0051704 134 0.102
single organism organelle organization GO:1902589 199 0.096
organonitrogen compound metabolic process GO:1901564 74 0.093
maintenance of location GO:0051235 4 0.093
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.089
cellular biosynthetic process GO:0044249 286 0.083
regulation of protein complex assembly GO:0043254 3 0.081
multicellular organism growth GO:0035264 4 0.081
positive regulation of blood circulation GO:1903524 2 0.079
heart development GO:0007507 313 0.077
cellular macromolecule metabolic process GO:0044260 391 0.077
amine metabolic process GO:0009308 2 0.075
regulation of wound healing GO:0061041 2 0.073
cellular amine metabolic process GO:0044106 2 0.070
regulation of gene expression GO:0010468 265 0.070
growth GO:0040007 174 0.067
regulation of metabolic process GO:0019222 359 0.067
cell migration GO:0016477 237 0.065
single organism transport GO:0044765 206 0.065
negative regulation of biological process GO:0048519 304 0.064
cell surface receptor signaling pathway GO:0007166 325 0.063
single organism localization GO:1902578 225 0.063
protein metabolic process GO:0019538 183 0.062
phosphate containing compound metabolic process GO:0006796 108 0.062
cellular component movement GO:0006928 335 0.061
signal transduction GO:0007165 455 0.061
cell motility GO:0048870 244 0.059
protein polymerization GO:0051258 4 0.058
regulation of cellular ketone metabolic process GO:0010565 7 0.058
nitrogen compound metabolic process GO:0006807 319 0.057
embryonic organ development GO:0048568 381 0.055
response to carbohydrate GO:0009743 3 0.053
cellular response to external stimulus GO:0071496 2 0.053
cell projection organization GO:0030030 284 0.052
regulation of cellular amine metabolic process GO:0033238 0 0.052
regulation of cellular amino acid metabolic process GO:0006521 0 0.052
skeletal system development GO:0001501 181 0.052
cell death GO:0008219 121 0.051
macromolecule biosynthetic process GO:0009059 227 0.051
regulation of macromolecule metabolic process GO:0060255 317 0.051
gene expression GO:0010467 252 0.049
regulation of nitrogen compound metabolic process GO:0051171 251 0.049
system process GO:0003008 185 0.049
aromatic compound biosynthetic process GO:0019438 217 0.049
phagocytosis engulfment GO:0006911 1 0.047
cellular component biogenesis GO:0044085 178 0.047
blood circulation GO:0008015 87 0.047
cognition GO:0050890 1 0.046
lipid storage GO:0019915 1 0.046
response to stress GO:0006950 263 0.046
actin polymerization or depolymerization GO:0008154 2 0.045
muscle structure development GO:0061061 196 0.045
cellular macromolecule biosynthetic process GO:0034645 224 0.043
regulation of response to stimulus GO:0048583 269 0.043
cellular ketone metabolic process GO:0042180 11 0.042
nucleoside monophosphate catabolic process GO:0009125 4 0.041
positive regulation of metabolic process GO:0009893 108 0.041
macromolecule modification GO:0043412 111 0.041
cytoskeleton organization GO:0007010 96 0.041
localization of cell GO:0051674 244 0.040
regulation of protein polymerization GO:0032271 2 0.039
chordate embryonic development GO:0043009 271 0.039
regulation of nucleotide catabolic process GO:0030811 2 0.039
regulation of blood pressure GO:0008217 1 0.039
cellular protein modification process GO:0006464 100 0.038
regulation of nucleoside metabolic process GO:0009118 2 0.038
embryo development ending in birth or egg hatching GO:0009792 271 0.038
cell part morphogenesis GO:0032990 246 0.038
regulation of endothelial cell proliferation GO:0001936 1 0.037
apoptotic process GO:0006915 116 0.037
regulation of multicellular organism growth GO:0040014 4 0.037
regulation of apoptotic process GO:0042981 98 0.037
ribonucleoside monophosphate catabolic process GO:0009158 4 0.037
meiotic nuclear division GO:0007126 4 0.037
positive regulation of transport GO:0051050 2 0.037
transport GO:0006810 220 0.037
regulation of cell communication GO:0010646 232 0.036
negative regulation of developmental process GO:0051093 65 0.036
nucleobase containing compound metabolic process GO:0006139 274 0.036
circulatory system process GO:0003013 87 0.036
regulation of purine nucleotide catabolic process GO:0033121 2 0.035
positive regulation of cellular catabolic process GO:0031331 3 0.035
cellular protein metabolic process GO:0044267 129 0.035
response to chemical GO:0042221 320 0.035
regulation of ion transmembrane transporter activity GO:0032412 2 0.034
cellular component morphogenesis GO:0032989 336 0.034
cellular response to nutrient levels GO:0031669 2 0.033
regulation of binding GO:0051098 3 0.033
skeletal system morphogenesis GO:0048705 102 0.032
regulation of cellular component organization GO:0051128 86 0.032
death GO:0016265 121 0.032
leukocyte proliferation GO:0070661 1 0.032
heterocycle metabolic process GO:0046483 290 0.032
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.031
immune system development GO:0002520 191 0.031
establishment of localization GO:0051234 244 0.031
fatty acid transport GO:0015908 1 0.031
cellular component disassembly GO:0022411 1 0.030
response to external stimulus GO:0009605 264 0.030
protein modification process GO:0036211 100 0.030
immune system process GO:0002376 241 0.030
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.030
extrinsic apoptotic signaling pathway GO:0097191 3 0.030
blood vessel development GO:0001568 246 0.030
positive regulation of cell cycle GO:0045787 3 0.030
cellular amino acid metabolic process GO:0006520 7 0.030
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.030
long chain fatty acid transport GO:0015909 1 0.030
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.029
response to monosaccharide GO:0034284 3 0.029
multi organism reproductive process GO:0044703 36 0.029
cytokinesis GO:0000910 3 0.029
regulation of reactive oxygen species metabolic process GO:2000377 2 0.029
nucleic acid metabolic process GO:0090304 244 0.029
striated muscle contraction GO:0006941 12 0.028
positive regulation of cellular amine metabolic process GO:0033240 0 0.028
regulation of signal transduction GO:0009966 225 0.028
protein import GO:0017038 3 0.028
biosynthetic process GO:0009058 294 0.028
taxis GO:0042330 109 0.028
phosphorus metabolic process GO:0006793 109 0.028
heterocycle biosynthetic process GO:0018130 215 0.027
developmental growth GO:0048589 166 0.027
positive regulation of catabolic process GO:0009896 4 0.027
macromolecular complex disassembly GO:0032984 1 0.026
negative regulation of signaling GO:0023057 96 0.026
protein localization to nucleus GO:0034504 3 0.026
actin filament based process GO:0030029 64 0.026
mitotic cell cycle process GO:1903047 48 0.026
regulation of multicellular organismal development GO:2000026 223 0.026
rna metabolic process GO:0016070 219 0.026
programmed cell death GO:0012501 119 0.025
regulation of erk1 and erk2 cascade GO:0070372 4 0.025
regulation of cellular protein metabolic process GO:0032268 52 0.025
regulation of reproductive process GO:2000241 4 0.025
cellular response to starvation GO:0009267 1 0.025
membrane invagination GO:0010324 1 0.025
adult behavior GO:0030534 2 0.025
regulation of macromolecule biosynthetic process GO:0010556 225 0.025
regulation of signaling GO:0023051 235 0.025
regulation of protein metabolic process GO:0051246 56 0.024
negative regulation of cell communication GO:0010648 96 0.024
carboxylic acid metabolic process GO:0019752 22 0.024
head development GO:0060322 303 0.024
carbohydrate derivative metabolic process GO:1901135 61 0.024
nucleic acid templated transcription GO:0097659 181 0.024
negative regulation of cytokine production GO:0001818 1 0.023
protein complex disassembly GO:0043241 1 0.023
cardiac muscle cell development GO:0055013 20 0.023
cellular component assembly GO:0022607 170 0.023
regulation of protein depolymerization GO:1901879 1 0.023
positive regulation of protein kinase b signaling GO:0051897 1 0.023
regulation of biosynthetic process GO:0009889 250 0.022
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.022
heart process GO:0003015 71 0.022
positive regulation of apoptotic signaling pathway GO:2001235 1 0.021
regulation of protein complex disassembly GO:0043244 1 0.021
nucleobase containing compound biosynthetic process GO:0034654 205 0.021
regulation of cellular component movement GO:0051270 55 0.021
transcription from rna polymerase ii promoter GO:0006366 80 0.021
cellular aromatic compound metabolic process GO:0006725 295 0.021
reactive nitrogen species metabolic process GO:2001057 0 0.021
single fertilization GO:0007338 3 0.021
aging GO:0007568 2 0.021
regulation of metal ion transport GO:0010959 4 0.021
muscle system process GO:0003012 20 0.021
response to other organism GO:0051707 97 0.021
negative regulation of secretion GO:0051048 2 0.021
transmembrane transport GO:0055085 120 0.021
positive regulation of cytoskeleton organization GO:0051495 3 0.021
positive regulation of map kinase activity GO:0043406 3 0.020
response to hexose GO:0009746 3 0.020
ameboidal type cell migration GO:0001667 143 0.020
regulation of cell shape GO:0008360 1 0.020
neuron projection development GO:0031175 180 0.020
oxoacid metabolic process GO:0043436 31 0.020
negative regulation of programmed cell death GO:0043069 58 0.020
regulation of vasculature development GO:1901342 33 0.020
oocyte development GO:0048599 14 0.020
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.019
regulation of protein binding GO:0043393 3 0.019
regulation of anatomical structure morphogenesis GO:0022603 130 0.019
embryonic skeletal system morphogenesis GO:0048704 93 0.019
intracellular signal transduction GO:0035556 85 0.019
regulation of nucleic acid templated transcription GO:1903506 213 0.019
actin filament based movement GO:0030048 1 0.019
cytoskeleton dependent cytokinesis GO:0061640 3 0.019
neuron development GO:0048666 262 0.019
small molecule metabolic process GO:0044281 77 0.019
angiogenesis GO:0001525 158 0.019
erk1 and erk2 cascade GO:0070371 4 0.019
negative regulation of signal transduction GO:0009968 94 0.019
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.019
wound healing GO:0042060 90 0.019
cell cycle arrest GO:0007050 1 0.019
chemosensory behavior GO:0007635 1 0.019
regulation of cellular biosynthetic process GO:0031326 245 0.018
organic acid metabolic process GO:0006082 31 0.018
regulation of cytokine production GO:0001817 3 0.018
generation of neurons GO:0048699 385 0.018
cartilage development GO:0051216 96 0.018
cellular response to extracellular stimulus GO:0031668 2 0.018
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.018
response to glucose GO:0009749 3 0.018
protein depolymerization GO:0051261 1 0.018
regulation of primary metabolic process GO:0080090 311 0.018
protein complex biogenesis GO:0070271 30 0.018
positive regulation of biological process GO:0048518 253 0.018
single organism biosynthetic process GO:0044711 71 0.018
ion transport GO:0006811 114 0.018
regulation of establishment of protein localization GO:0070201 4 0.018
nuclear migration GO:0007097 3 0.018
response to glucocorticoid GO:0051384 1 0.018
response to nutrient GO:0007584 3 0.018
nuclear import GO:0051170 3 0.017
cation transmembrane transport GO:0098655 65 0.017
response to vitamin GO:0033273 3 0.017
positive regulation of nucleoside metabolic process GO:0045979 1 0.017
response to wounding GO:0009611 116 0.017
muscle organ development GO:0007517 101 0.017
rna biosynthetic process GO:0032774 181 0.017
regulation of molecular function GO:0065009 70 0.017
sleep GO:0030431 1 0.017
glycerophospholipid biosynthetic process GO:0046474 1 0.017
spermatid development GO:0007286 2 0.017
ribonucleotide metabolic process GO:0009259 27 0.017
positive regulation of gtp catabolic process GO:0033126 1 0.017
regulation of cell motility GO:2000145 46 0.017
reactive oxygen species metabolic process GO:0072593 6 0.017
regulation of epithelial cell proliferation GO:0050678 3 0.017
positive regulation of cell activation GO:0050867 1 0.017
regulation of anatomical structure size GO:0090066 33 0.016
axon development GO:0061564 166 0.016
cellular response to chemical stimulus GO:0070887 157 0.016
regulation of ph GO:0006885 3 0.016
regulation of cell size GO:0008361 29 0.016
developmental growth involved in morphogenesis GO:0060560 86 0.016
positive regulation of cellular process GO:0048522 201 0.016
regulation of cell activation GO:0050865 1 0.016
regulation of inflammatory response GO:0050727 2 0.016
organic cyclic compound metabolic process GO:1901360 301 0.016
phosphorylation GO:0016310 69 0.016
regulation of rna biosynthetic process GO:2001141 213 0.016
cellular carbohydrate metabolic process GO:0044262 4 0.015
ion transmembrane transport GO:0034220 91 0.015
embryonic skeletal system development GO:0048706 97 0.015
multicellular organismal metabolic process GO:0044236 2 0.015
organelle assembly GO:0070925 110 0.015
cell morphogenesis involved in differentiation GO:0000904 195 0.015
cellular response to organic substance GO:0071310 105 0.015
regulation of nucleotide metabolic process GO:0006140 17 0.015
protein stabilization GO:0050821 2 0.015
positive regulation of response to stimulus GO:0048584 80 0.015
neuron differentiation GO:0030182 353 0.015
establishment of protein localization to organelle GO:0072594 4 0.015
response to organic substance GO:0010033 153 0.015
negative regulation of protein phosphorylation GO:0001933 4 0.015
response to corticosteroid GO:0031960 1 0.015
regulation of localization GO:0032879 104 0.015
cellular nitrogen compound biosynthetic process GO:0044271 218 0.015
positive regulation of nucleotide catabolic process GO:0030813 1 0.015
modification dependent macromolecule catabolic process GO:0043632 3 0.015
sensory organ development GO:0007423 393 0.015
regulation of tube size GO:0035150 2 0.015
cell adhesion mediated by integrin GO:0033627 1 0.015
regulation of blood vessel size GO:0050880 2 0.015
cell cycle GO:0007049 93 0.015
regulation of muscle contraction GO:0006937 3 0.015
gastrulation GO:0007369 208 0.014
regulation of rna metabolic process GO:0051252 224 0.014
organic substance biosynthetic process GO:1901576 289 0.014
cardiac cell development GO:0055006 21 0.014
embryonic limb morphogenesis GO:0030326 2 0.014
hemopoiesis GO:0030097 183 0.014
regulation of locomotion GO:0040012 55 0.014
nucleocytoplasmic transport GO:0006913 4 0.014
regulation of transmembrane transporter activity GO:0022898 2 0.014
embryonic cranial skeleton morphogenesis GO:0048701 90 0.014
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.014
hematopoietic or lymphoid organ development GO:0048534 191 0.014
mononuclear cell proliferation GO:0032943 1 0.014
purine nucleoside monophosphate catabolic process GO:0009128 4 0.014
developmental programmed cell death GO:0010623 4 0.014
cellular response to endogenous stimulus GO:0071495 68 0.014
female gamete generation GO:0007292 14 0.014
regulation of phosphorus metabolic process GO:0051174 43 0.014
nuclear transport GO:0051169 4 0.014
regulation of mrna processing GO:0050684 3 0.014
regulation of programmed cell death GO:0043067 101 0.014
regulation of cell death GO:0010941 103 0.014
cell projection morphogenesis GO:0048858 244 0.014
modification dependent protein catabolic process GO:0019941 3 0.014
regulation of striated muscle contraction GO:0006942 2 0.014
regulation of myotube differentiation GO:0010830 2 0.014
cellular protein catabolic process GO:0044257 4 0.014
renal system process involved in regulation of systemic arterial blood pressure GO:0003071 1 0.014
gamete generation GO:0007276 33 0.014
mitotic cytokinesis GO:0000281 3 0.014
positive regulation of wound healing GO:0090303 1 0.014
cellular amide metabolic process GO:0043603 4 0.014
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.014
regulation of cell projection assembly GO:0060491 4 0.013
ventricular cardiac muscle tissue development GO:0003229 3 0.013
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.013
tube morphogenesis GO:0035239 349 0.013
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.013
adherens junction organization GO:0034332 4 0.013
regulation of gtpase activity GO:0043087 2 0.013
apoptotic process involved in development GO:1902742 2 0.013
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.013
membrane fusion GO:0061025 2 0.013
response to estrogen GO:0043627 27 0.013
organic cyclic compound biosynthetic process GO:1901362 223 0.013
brain development GO:0007420 293 0.013
maternal determination of anterior posterior axis embryo GO:0008358 4 0.013
regulation of phosphate metabolic process GO:0019220 43 0.013
regulation of intracellular signal transduction GO:1902531 57 0.013
multicellular organismal macromolecule metabolic process GO:0044259 2 0.013
cell cycle process GO:0022402 53 0.013
regulation of angiogenesis GO:0045765 26 0.012
transcription dna templated GO:0006351 181 0.012
macromolecule localization GO:0033036 54 0.012
embryonic organ morphogenesis GO:0048562 274 0.012
positive regulation of chemotaxis GO:0050921 5 0.012
fertilization GO:0009566 3 0.012
cardiac muscle fiber development GO:0048739 3 0.012
positive regulation of cell adhesion GO:0045785 1 0.012
protein import into nucleus GO:0006606 3 0.012
regulation of cytoplasmic transport GO:1903649 4 0.012
morphogenesis of an epithelium GO:0002009 333 0.012
regulation of transcription dna templated GO:0006355 213 0.012
protein phosphorylation GO:0006468 47 0.012
behavior GO:0007610 74 0.012
eye development GO:0001654 277 0.012
hormone transport GO:0009914 2 0.012
cellular component assembly involved in morphogenesis GO:0010927 107 0.012
hematopoietic stem cell migration GO:0035701 4 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.012
positive regulation of heart contraction GO:0045823 2 0.012
nitric oxide metabolic process GO:0046209 2 0.011
response to endogenous stimulus GO:0009719 83 0.011
striated muscle cell development GO:0055002 108 0.011
cellular catabolic process GO:0044248 27 0.011
regulation of hydrolase activity GO:0051336 28 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.011
regulation of protein transport GO:0051223 3 0.011
response to drug GO:0042493 3 0.011
regulation of cell development GO:0060284 100 0.011
regulation of synaptic plasticity GO:0048167 1 0.011
connective tissue development GO:0061448 99 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.011
response to external biotic stimulus GO:0043207 97 0.011
chemotaxis GO:0006935 104 0.011
long chain fatty acid metabolic process GO:0001676 1 0.011
protein homooligomerization GO:0051260 3 0.011
muscle cell differentiation GO:0042692 139 0.011
ear development GO:0043583 127 0.011
defense response to fungus GO:0050832 2 0.011
positive regulation of secretion GO:0051047 1 0.011
negative regulation of cellular metabolic process GO:0031324 77 0.011
gtp metabolic process GO:0046039 4 0.011
odontogenesis of dentin containing tooth GO:0042475 1 0.011
proteasomal protein catabolic process GO:0010498 2 0.011
renal system process involved in regulation of blood volume GO:0001977 1 0.011
positive regulation of epithelial cell migration GO:0010634 2 0.011
endochondral bone growth GO:0003416 2 0.011
regulation of axonogenesis GO:0050770 32 0.011
regulation of glomerular filtration GO:0003093 1 0.011
homeostatic process GO:0042592 142 0.011
regulation of systemic arterial blood pressure GO:0003073 1 0.010
reactive oxygen species biosynthetic process GO:1903409 1 0.010
positive regulation of cellular component biogenesis GO:0044089 3 0.010
intracellular mrna localization GO:0008298 1 0.010
defense response GO:0006952 47 0.010
centrosome organization GO:0051297 1 0.010
protein complex assembly GO:0006461 30 0.010
reproductive process GO:0022414 40 0.010
cellular protein complex disassembly GO:0043624 1 0.010
heart morphogenesis GO:0003007 156 0.010
lamellipodium assembly GO:0030032 1 0.010
multicellular organismal response to stress GO:0033555 2 0.010
positive regulation of cell communication GO:0010647 56 0.010
single organism nuclear import GO:1902593 3 0.010
negative regulation of dna metabolic process GO:0051053 4 0.010
apoptotic process involved in morphogenesis GO:0060561 2 0.010
positive regulation of catalytic activity GO:0043085 25 0.010
organism emergence from protective structure GO:0071684 4 0.010
regulation of growth GO:0040008 42 0.010
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.010
hindbrain development GO:0030902 91 0.010
positive regulation of endothelial cell proliferation GO:0001938 1 0.010
positive regulation of endothelial cell migration GO:0010595 2 0.010
complement activation GO:0006956 3 0.010
regulation of microtubule cytoskeleton organization GO:0070507 3 0.010

zgc:92806 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.167
musculoskeletal system disease DOID:17 0 0.121
muscular disease DOID:0080000 0 0.066
muscle tissue disease DOID:66 0 0.066
myopathy DOID:423 0 0.030
heart disease DOID:114 0 0.030
cardiomyopathy DOID:0050700 0 0.030
cardiovascular system disease DOID:1287 0 0.030
distal arthrogryposis DOID:0050646 0 0.026
hypertrophic cardiomyopathy DOID:11984 0 0.023
intrinsic cardiomyopathy DOID:0060036 0 0.023
nervous system disease DOID:863 0 0.019
bone development disease DOID:0080006 0 0.016
bone disease DOID:0080001 0 0.016
connective tissue disease DOID:65 0 0.016
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
organ system cancer DOID:0050686 0 0.013