Danio rerio

111 known processes

ptbp1a

polypyrimidine tract binding protein 1a

(Aliases: zgc:110689,ptbp1,wu:fb99f12)

ptbp1a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
establishment of localization GO:0051234 244 0.464
signal transduction GO:0007165 455 0.211
regulation of biological quality GO:0065008 263 0.195
digestive system development GO:0055123 289 0.178
digestive tract development GO:0048565 265 0.176
cortical actin cytoskeleton organization GO:0030866 1 0.169
regulation of cell shape GO:0008360 1 0.168
single organism localization GO:1902578 225 0.143
aging GO:0007568 2 0.141
digestive tract morphogenesis GO:0048546 231 0.139
multicellular organism growth GO:0035264 4 0.133
muscle cell differentiation GO:0042692 139 0.114
Human
cell morphogenesis GO:0000902 289 0.103
gastrulation GO:0007369 208 0.097
regulation of anatomical structure morphogenesis GO:0022603 130 0.096
tube morphogenesis GO:0035239 349 0.095
positive regulation of biological process GO:0048518 253 0.089
macromolecule localization GO:0033036 54 0.080
neuron differentiation GO:0030182 353 0.080
regulation of gene expression GO:0010468 265 0.079
Human Mouse Fly
regulation of metabolic process GO:0019222 359 0.079
Human Mouse Fly
ubiquitin dependent protein catabolic process GO:0006511 3 0.079
generation of neurons GO:0048699 385 0.078
vasculature development GO:0001944 278 0.075
regulation of signal transduction GO:0009966 225 0.069
mitotic cell cycle process GO:1903047 48 0.068
cellular nitrogen compound metabolic process GO:0034641 290 0.067
Human Mouse Rat
epiboly GO:0090504 41 0.065
blood vessel morphogenesis GO:0048514 216 0.062
regulation of biosynthetic process GO:0009889 250 0.061
Fly
regulation of cellular metabolic process GO:0031323 320 0.058
Human Mouse Fly
heart development GO:0007507 313 0.058
organelle organization GO:0006996 227 0.053
Fly
regulation of anatomical structure size GO:0090066 33 0.053
peptidyl serine modification GO:0018209 2 0.052
peptidyl serine phosphorylation GO:0018105 1 0.052
cellular macromolecule metabolic process GO:0044260 391 0.050
Human Mouse Rat Fly
blood circulation GO:0008015 87 0.050
morphogenesis of an epithelium GO:0002009 333 0.049
positive regulation of cellular process GO:0048522 201 0.049
neuron projection morphogenesis GO:0048812 161 0.047
rna metabolic process GO:0016070 219 0.046
Human Mouse Rat
blood vessel development GO:0001568 246 0.046
single organism metabolic process GO:0044710 217 0.046
nuclear transport GO:0051169 4 0.043
embryonic heart tube development GO:0035050 133 0.043
regulation of protein catabolic process GO:0042176 1 0.042
response to chemical GO:0042221 320 0.042
larval development GO:0002164 2 0.041
cell surface receptor signaling pathway GO:0007166 325 0.041
transport GO:0006810 220 0.041
embryonic limb morphogenesis GO:0030326 2 0.041
mrna stabilization GO:0048255 4 0.041
regulation of developmental process GO:0050793 247 0.041
Human
cell migration GO:0016477 237 0.040
organic cyclic compound metabolic process GO:1901360 301 0.040
Human Mouse Rat
modification dependent protein catabolic process GO:0019941 3 0.039
regulation of signaling GO:0023051 235 0.038
positive regulation of map kinase activity GO:0043406 3 0.038
cell projection morphogenesis GO:0048858 244 0.038
phosphate containing compound metabolic process GO:0006796 108 0.038
negative regulation of biological process GO:0048519 304 0.038
negative regulation of muscle cell differentiation GO:0051148 1 0.037
Human
cellular component morphogenesis GO:0032989 336 0.036
lipid storage GO:0019915 1 0.036
meiotic nuclear division GO:0007126 4 0.036
modification dependent macromolecule catabolic process GO:0043632 3 0.036
intracellular signal transduction GO:0035556 85 0.034
tissue regeneration GO:0042246 74 0.034
angiogenesis GO:0001525 158 0.033
regulation of macromolecule biosynthetic process GO:0010556 225 0.033
Fly
immune system process GO:0002376 241 0.032
response to abiotic stimulus GO:0009628 122 0.032
epithelial cell differentiation GO:0030855 116 0.032
multicellular organismal signaling GO:0035637 22 0.031
regulation of cell communication GO:0010646 232 0.031
embryonic organ morphogenesis GO:0048562 274 0.030
negative regulation of metabolic process GO:0009892 86 0.030
Human Mouse Fly
muscle structure development GO:0061061 196 0.030
Human
anterior posterior pattern specification GO:0009952 152 0.030
proteasomal protein catabolic process GO:0010498 2 0.029
cortical cytoskeleton organization GO:0030865 1 0.029
regulation of membrane potential GO:0042391 23 0.029
meiotic cell cycle process GO:1903046 3 0.029
response to stress GO:0006950 263 0.029
Fly
guanosine containing compound catabolic process GO:1901069 2 0.029
cell part morphogenesis GO:0032990 246 0.028
positive regulation of catabolic process GO:0009896 4 0.027
regulation of rna biosynthetic process GO:2001141 213 0.027
cellular response to extracellular stimulus GO:0031668 2 0.027
cell cycle process GO:0022402 53 0.027
wnt signaling pathway GO:0016055 80 0.026
gtp metabolic process GO:0046039 4 0.026
regulation of nucleic acid templated transcription GO:1903506 213 0.025
response to salt stress GO:0009651 10 0.025
organic substance biosynthetic process GO:1901576 289 0.025
Fly
ras protein signal transduction GO:0007265 7 0.025
cellular component assembly GO:0022607 170 0.025
cortical granule exocytosis GO:0060471 1 0.025
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.025
regulation of nitrogen compound metabolic process GO:0051171 251 0.025
Human Mouse
heart morphogenesis GO:0003007 156 0.025
cell adhesion GO:0007155 40 0.024
positive regulation of cellular catabolic process GO:0031331 3 0.024
nucleobase containing compound biosynthetic process GO:0034654 205 0.024
developmental growth GO:0048589 166 0.024
rna stabilization GO:0043489 4 0.024
protein dephosphorylation GO:0006470 3 0.024
neurotransmitter secretion GO:0007269 2 0.024
embryonic pattern specification GO:0009880 44 0.024
cell projection organization GO:0030030 284 0.023
regulation of cellular protein catabolic process GO:1903362 1 0.023
convergent extension GO:0060026 118 0.023
regulation of system process GO:0044057 40 0.023
regulation of multicellular organismal process GO:0051239 277 0.022
positive regulation of secretion GO:0051047 1 0.022
regulation of protein targeting GO:1903533 2 0.022
response to external stimulus GO:0009605 264 0.022
negative regulation of cellular process GO:0048523 283 0.022
wound healing GO:0042060 90 0.022
mitotic cell cycle GO:0000278 64 0.022
muscle cell development GO:0055001 115 0.022
regulation of cytoplasmic transport GO:1903649 4 0.022
positive regulation of gtpase activity GO:0043547 1 0.021
nitrogen compound metabolic process GO:0006807 319 0.021
Human Mouse Rat
regulation of nucleoside metabolic process GO:0009118 2 0.021
microtubule based process GO:0007017 60 0.021
Fly
positive regulation of transport GO:0051050 2 0.021
regulation of nucleotide catabolic process GO:0030811 2 0.021
regulation of meiotic cell cycle GO:0051445 1 0.021
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.020
determination of bilateral symmetry GO:0009855 204 0.020
positive regulation of secretion by cell GO:1903532 1 0.020
response to wounding GO:0009611 116 0.020
odontogenesis of dentin containing tooth GO:0042475 1 0.020
interspecies interaction between organisms GO:0044419 4 0.020
gtp catabolic process GO:0006184 2 0.020
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.020
Human Mouse
death GO:0016265 121 0.020
protein import GO:0017038 3 0.020
positive regulation of apoptotic signaling pathway GO:2001235 1 0.020
regulation of multicellular organism growth GO:0040014 4 0.020
positive regulation of nucleoside metabolic process GO:0045979 1 0.020
morphogenesis of an epithelial sheet GO:0002011 49 0.019
regulation of cellular biosynthetic process GO:0031326 245 0.019
Fly
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.019
cellular aromatic compound metabolic process GO:0006725 295 0.019
Human Mouse Rat
apical junction assembly GO:0043297 1 0.019
small gtpase mediated signal transduction GO:0007264 8 0.019
maintenance of location GO:0051235 4 0.019
exocytosis GO:0006887 1 0.019
stem cell proliferation GO:0072089 4 0.019
regulation of exocytosis GO:0017157 1 0.019
regulation of chromosome segregation GO:0051983 1 0.019
regulation of stem cell differentiation GO:2000736 4 0.019
nucleobase containing compound metabolic process GO:0006139 274 0.019
Human Mouse Rat
regulation of response to stimulus GO:0048583 269 0.019
negative regulation of catabolic process GO:0009895 3 0.019
rna processing GO:0006396 25 0.019
Human Mouse Rat
neurotransmitter transport GO:0006836 2 0.018
regulation of cell morphogenesis GO:0022604 42 0.018
cell division GO:0051301 20 0.018
organic substance transport GO:0071702 58 0.018
regulation of macromolecule metabolic process GO:0060255 317 0.018
Human Mouse Fly
vesicle mediated transport GO:0016192 22 0.018
establishment of protein localization to organelle GO:0072594 4 0.018
protein metabolic process GO:0019538 183 0.018
Fly
inner ear development GO:0048839 126 0.018
locomotion GO:0040011 313 0.018
biological adhesion GO:0022610 40 0.018
regulation of translational initiation GO:0006446 1 0.018
developmental growth involved in morphogenesis GO:0060560 86 0.018
actin mediated cell contraction GO:0070252 1 0.018
system process GO:0003008 185 0.018
heterocycle metabolic process GO:0046483 290 0.018
Human Mouse Rat
regulation of purine nucleotide catabolic process GO:0033121 2 0.018
detection of temperature stimulus GO:0016048 0 0.017
cellular protein metabolic process GO:0044267 129 0.017
Fly
circulatory system process GO:0003013 87 0.017
response to topologically incorrect protein GO:0035966 2 0.017
spindle assembly GO:0051225 2 0.017
small molecule metabolic process GO:0044281 77 0.017
cell morphogenesis involved in differentiation GO:0000904 195 0.017
cell substrate adhesion GO:0031589 4 0.017
cellular macromolecular complex assembly GO:0034622 24 0.016
adherens junction organization GO:0034332 4 0.016
autophagy GO:0006914 4 0.016
regulation of cell size GO:0008361 29 0.016
rna localization GO:0006403 4 0.016
regulation of establishment of protein localization GO:0070201 4 0.016
epithelial tube morphogenesis GO:0060562 148 0.016
membrane fusion GO:0061025 2 0.015
organelle fusion GO:0048284 3 0.015
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.015
meiotic chromosome segregation GO:0045132 3 0.015
localization within membrane GO:0051668 1 0.015
actin filament based movement GO:0030048 1 0.015
cellular protein catabolic process GO:0044257 4 0.015
cell death GO:0008219 121 0.015
protein localization to nucleus GO:0034504 3 0.015
positive regulation of gtp catabolic process GO:0033126 1 0.015
negative regulation of cellular catabolic process GO:0031330 3 0.015
negative regulation of biosynthetic process GO:0009890 55 0.015
Fly
biosynthetic process GO:0009058 294 0.015
Fly
mitotic cytokinesis GO:0000281 3 0.015
regulation of striated muscle contraction GO:0006942 2 0.015
cellular amine metabolic process GO:0044106 2 0.015
neuron projection development GO:0031175 180 0.014
muscle cell migration GO:0014812 4 0.014
growth GO:0040007 174 0.014
positive regulation of response to stimulus GO:0048584 80 0.014
endothelial cell differentiation GO:0045446 20 0.014
regulation of multicellular organismal development GO:2000026 223 0.014
cellular component disassembly GO:0022411 1 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.014
negative regulation of signaling GO:0023057 96 0.014
regulation of stem cell proliferation GO:0072091 2 0.014
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.014
regulation of protein transport GO:0051223 3 0.014
rna biosynthetic process GO:0032774 181 0.014
stem cell division GO:0017145 1 0.014
regulation of synaptic plasticity GO:0048167 1 0.014
axon extension GO:0048675 45 0.014
guanosine containing compound metabolic process GO:1901068 4 0.014
regulation of cardiac muscle cell contraction GO:0086004 1 0.013
synaptic vesicle localization GO:0097479 1 0.013
protein localization to plasma membrane GO:0072659 1 0.013
g2 dna damage checkpoint GO:0031572 3 0.013
rho protein signal transduction GO:0007266 5 0.013
organelle assembly GO:0070925 110 0.013
peptide transport GO:0015833 1 0.013
positive regulation of exocytosis GO:0045921 1 0.013
gene expression GO:0010467 252 0.013
Human Mouse Rat Fly
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.013
regulation of nucleocytoplasmic transport GO:0046822 2 0.013
adherens junction assembly GO:0034333 1 0.013
neuronal action potential GO:0019228 18 0.013
transmission of nerve impulse GO:0019226 19 0.013
cellular localization GO:0051641 97 0.013
transcription dna templated GO:0006351 181 0.013
action potential GO:0001508 19 0.013
actin filament based process GO:0030029 64 0.013
cellular ketone metabolic process GO:0042180 11 0.013
embryonic heart tube morphogenesis GO:0003143 108 0.013
enzyme linked receptor protein signaling pathway GO:0007167 106 0.013
multi organism process GO:0051704 134 0.013
tissue remodeling GO:0048771 4 0.013
segmentation GO:0035282 97 0.013
activation of mapk activity GO:0000187 3 0.013
chemical homeostasis GO:0048878 49 0.013
negative regulation of wnt signaling pathway GO:0030178 30 0.013
positive regulation of metabolic process GO:0009893 108 0.013
regulation of cellular ketone metabolic process GO:0010565 7 0.013
extrinsic apoptotic signaling pathway GO:0097191 3 0.013
establishment of rna localization GO:0051236 3 0.013
negative regulation of kinase activity GO:0033673 4 0.013
somatic muscle development GO:0007525 4 0.013
transcription from rna polymerase iii promoter GO:0006383 1 0.013
regulation of erk1 and erk2 cascade GO:0070372 4 0.012
regulation of gtpase activity GO:0043087 2 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.012
establishment of protein localization to plasma membrane GO:0090002 1 0.012
regulation of wnt signaling pathway GO:0030111 53 0.012
erk1 and erk2 cascade GO:0070371 4 0.012
taxis GO:0042330 109 0.012
sexual reproduction GO:0019953 36 0.012
response to osmotic stress GO:0006970 11 0.012
embryonic organ development GO:0048568 381 0.012
cellular biosynthetic process GO:0044249 286 0.012
Fly
single organism nuclear import GO:1902593 3 0.012
positive regulation of cell adhesion GO:0045785 1 0.012
skeletal system development GO:0001501 181 0.012
cation transmembrane transport GO:0098655 65 0.012
appendage morphogenesis GO:0035107 56 0.012
Fly
regulation of cell development GO:0060284 100 0.012
heart contraction GO:0060047 71 0.012
cellular catabolic process GO:0044248 27 0.012
positive regulation of translation GO:0045727 1 0.012
transcription from rna polymerase ii promoter GO:0006366 80 0.012
inorganic ion transmembrane transport GO:0098660 57 0.012
stem cell fate commitment GO:0048865 1 0.012
phosphorus metabolic process GO:0006793 109 0.011
striated muscle cell differentiation GO:0051146 129 0.011
multicellular organismal homeostasis GO:0048871 29 0.011
regulation of rna metabolic process GO:0051252 224 0.011
Human Mouse
cytoskeleton organization GO:0007010 96 0.011
Fly
protein phosphorylation GO:0006468 47 0.011
regulation of metal ion transport GO:0010959 4 0.011
hemopoiesis GO:0030097 183 0.011
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.011
regulation of protein localization to nucleus GO:1900180 2 0.011
regulation of cellular component organization GO:0051128 86 0.011
regulation of primary metabolic process GO:0080090 311 0.011
Human Mouse Fly
regulation of blood vessel size GO:0050880 2 0.011
stem cell maintenance GO:0019827 4 0.011
protein localization GO:0008104 40 0.011
secondary metabolic process GO:0019748 3 0.011
regulation of intracellular signal transduction GO:1902531 57 0.011
positive regulation of reproductive process GO:2000243 2 0.011
organelle localization GO:0051640 49 0.011
osteoclast differentiation GO:0030316 1 0.011
regulation of calcium ion dependent exocytosis GO:0017158 1 0.011
negative regulation of protein kinase activity GO:0006469 4 0.011
single organism organelle organization GO:1902589 199 0.011
Fly
regulation of circadian rhythm GO:0042752 4 0.011
neuroblast proliferation GO:0007405 2 0.011
response to external biotic stimulus GO:0043207 97 0.011
gastrulation with mouth forming second GO:0001702 44 0.011
developmental cell growth GO:0048588 52 0.011
cellular component assembly involved in morphogenesis GO:0010927 107 0.011
protein import into nucleus GO:0006606 3 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.011
neuron projection extension GO:1990138 45 0.011
regulation of dendrite development GO:0050773 3 0.011
cellular response to organic cyclic compound GO:0071407 38 0.011
positive regulation of gene expression GO:0010628 71 0.010
appendage development GO:0048736 80 0.010
Fly
regulation of cellular component size GO:0032535 30 0.010
lymphangiogenesis GO:0001946 25 0.010
multi organism reproductive process GO:0044703 36 0.010
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.010
lymph vessel development GO:0001945 27 0.010
muscle contraction GO:0006936 18 0.010
macromolecular complex disassembly GO:0032984 1 0.010
cell cell signaling GO:0007267 52 0.010
hormone transport GO:0009914 2 0.010
specification of organ identity GO:0010092 2 0.010
positive regulation of nucleotide catabolic process GO:0030813 1 0.010
cartilage development GO:0051216 96 0.010
chordate embryonic development GO:0043009 271 0.010

ptbp1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.030
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013