Danio rerio

0 known processes

thbs3a

thrombospondin 3a

(Aliases: tsp3,zgc:103461,MGC103461,thbs3)

thbs3a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sensory organ development GO:0007423 393 0.473
regulation of cell differentiation GO:0045595 142 0.383
regulation of multicellular organismal process GO:0051239 277 0.329
regulation of developmental process GO:0050793 247 0.227
positive regulation of cellular component biogenesis GO:0044089 3 0.165
regulation of multicellular organismal development GO:2000026 223 0.155
morphogenesis of an epithelium GO:0002009 333 0.147
nitrogen compound metabolic process GO:0006807 319 0.147
response to organic substance GO:0010033 153 0.130
central nervous system development GO:0007417 387 0.113
regulation of synapse assembly GO:0051963 3 0.112
heart development GO:0007507 313 0.110
chordate embryonic development GO:0043009 271 0.106
synaptic growth at neuromuscular junction GO:0051124 2 0.099
cellular aromatic compound metabolic process GO:0006725 295 0.097
response to chemical GO:0042221 320 0.097
regulation of biological quality GO:0065008 263 0.097
regulation of synapse organization GO:0050807 3 0.093
cell motility GO:0048870 244 0.092
larval development GO:0002164 2 0.091
cellular response to chemical stimulus GO:0070887 157 0.090
developmental growth GO:0048589 166 0.088
signal transduction GO:0007165 455 0.087
carboxylic acid metabolic process GO:0019752 22 0.084
cellular response to organic substance GO:0071310 105 0.084
regulation of signal transduction GO:0009966 225 0.084
aging GO:0007568 2 0.083
organic acid metabolic process GO:0006082 31 0.082
regulation of anatomical structure morphogenesis GO:0022603 130 0.082
regulation of multicellular organism growth GO:0040014 4 0.082
muscle tissue development GO:0060537 110 0.081
regulation of response to stimulus GO:0048583 269 0.080
organic cyclic compound metabolic process GO:1901360 301 0.080
muscle structure development GO:0061061 196 0.079
cellular response to endogenous stimulus GO:0071495 68 0.078
eye development GO:0001654 277 0.076
heterocycle metabolic process GO:0046483 290 0.075
positive regulation of catabolic process GO:0009896 4 0.074
maintenance of location GO:0051235 4 0.074
regulation of cell shape GO:0008360 1 0.073
negative regulation of biological process GO:0048519 304 0.071
regulation of nervous system development GO:0051960 90 0.070
cell migration GO:0016477 237 0.069
head development GO:0060322 303 0.068
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.068
cell morphogenesis GO:0000902 289 0.067
response to endogenous stimulus GO:0009719 83 0.065
response to growth factor GO:0070848 39 0.065
regulation of biomineral tissue development GO:0070167 2 0.065
locomotion GO:0040011 313 0.064
response to external stimulus GO:0009605 264 0.063
organonitrogen compound metabolic process GO:1901564 74 0.062
response to stress GO:0006950 263 0.062
positive regulation of transport GO:0051050 2 0.061
negative regulation of multicellular organismal process GO:0051241 69 0.061
neurotransmitter transport GO:0006836 2 0.060
regulation of cellular metabolic process GO:0031323 320 0.060
immune system process GO:0002376 241 0.060
negative regulation of cellular process GO:0048523 283 0.059
multicellular organism growth GO:0035264 4 0.059
sensory organ morphogenesis GO:0090596 200 0.058
response to nutrient GO:0007584 3 0.057
tube morphogenesis GO:0035239 349 0.056
eye morphogenesis GO:0048592 144 0.056
embryonic organ development GO:0048568 381 0.055
positive regulation of biological process GO:0048518 253 0.054
ribonucleoside monophosphate catabolic process GO:0009158 4 0.053
regulation of signaling GO:0023051 235 0.053
rna biosynthetic process GO:0032774 181 0.053
regulation of protein complex assembly GO:0043254 3 0.053
protein metabolic process GO:0019538 183 0.053
embryonic organ morphogenesis GO:0048562 274 0.051
enzyme linked receptor protein signaling pathway GO:0007167 106 0.051
cellular macromolecule metabolic process GO:0044260 391 0.051
muscle organ development GO:0007517 101 0.050
regionalization GO:0003002 274 0.050
growth GO:0040007 174 0.049
cellular nitrogen compound metabolic process GO:0034641 290 0.049
oxoacid metabolic process GO:0043436 31 0.049
regulation of metabolic process GO:0019222 359 0.049
cellular macromolecule biosynthetic process GO:0034645 224 0.048
small molecule metabolic process GO:0044281 77 0.048
regulation of primary metabolic process GO:0080090 311 0.048
establishment of localization GO:0051234 244 0.048
angiogenesis GO:0001525 158 0.046
response to glucocorticoid GO:0051384 1 0.045
epithelial tube morphogenesis GO:0060562 148 0.045
generation of neurons GO:0048699 385 0.045
regulation of reproductive process GO:2000241 4 0.044
negative regulation of blood circulation GO:1903523 2 0.044
transport GO:0006810 220 0.043
regulation of cell morphogenesis GO:0022604 42 0.043
atp catabolic process GO:0006200 4 0.042
blood vessel development GO:0001568 246 0.041
organic substance biosynthetic process GO:1901576 289 0.041
regulation of cell development GO:0060284 100 0.041
cell surface receptor signaling pathway GO:0007166 325 0.041
positive regulation of protein complex assembly GO:0031334 2 0.040
lipid storage GO:0019915 1 0.040
response to corticosteroid GO:0031960 1 0.040
cellular amine metabolic process GO:0044106 2 0.040
regulation of localization GO:0032879 104 0.039
cellular component morphogenesis GO:0032989 336 0.038
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.038
cellular component movement GO:0006928 335 0.037
cellular response to external stimulus GO:0071496 2 0.037
regulation of nitrogen compound metabolic process GO:0051171 251 0.037
cellular amino acid metabolic process GO:0006520 7 0.037
nucleic acid metabolic process GO:0090304 244 0.036
skeletal system development GO:0001501 181 0.036
biosynthetic process GO:0009058 294 0.036
cellular component assembly GO:0022607 170 0.036
response to hormone GO:0009725 48 0.035
specification of symmetry GO:0009799 204 0.035
regulation of binding GO:0051098 3 0.034
negative regulation of synapse assembly GO:0051964 2 0.034
neuron differentiation GO:0030182 353 0.034
cellular component biogenesis GO:0044085 178 0.034
camera type eye development GO:0043010 222 0.034
positive regulation of cellular process GO:0048522 201 0.033
regulation of dna replication GO:0006275 3 0.033
regulation of epithelial cell proliferation GO:0050678 3 0.032
response to drug GO:0042493 3 0.032
regulation of cellular amino acid metabolic process GO:0006521 0 0.032
cellular ketone metabolic process GO:0042180 11 0.032
determination of left right symmetry GO:0007368 179 0.031
response to steroid hormone GO:0048545 35 0.031
cellular response to organic cyclic compound GO:0071407 38 0.031
alpha amino acid metabolic process GO:1901605 3 0.031
nucleobase containing compound metabolic process GO:0006139 274 0.030
nucleoside monophosphate catabolic process GO:0009125 4 0.029
hemopoiesis GO:0030097 183 0.029
amine metabolic process GO:0009308 2 0.029
response to abiotic stimulus GO:0009628 122 0.029
cell morphogenesis involved in differentiation GO:0000904 195 0.029
regulation of extent of cell growth GO:0061387 29 0.029
axonogenesis GO:0007409 152 0.029
single organism localization GO:1902578 225 0.029
positive regulation of nucleotide catabolic process GO:0030813 1 0.028
regulation of cellular biosynthetic process GO:0031326 245 0.028
neuron projection development GO:0031175 180 0.028
cellular modified amino acid metabolic process GO:0006575 3 0.028
positive regulation of cellular catabolic process GO:0031331 3 0.028
aromatic compound biosynthetic process GO:0019438 217 0.028
nucleic acid templated transcription GO:0097659 181 0.028
cell part morphogenesis GO:0032990 246 0.028
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.027
cellular response to steroid hormone stimulus GO:0071383 31 0.027
regulation of rna biosynthetic process GO:2001141 213 0.027
heterocycle biosynthetic process GO:0018130 215 0.027
embryonic heart tube morphogenesis GO:0003143 108 0.026
regulation of cell communication GO:0010646 232 0.026
heart morphogenesis GO:0003007 156 0.026
regulation of cellular component organization GO:0051128 86 0.026
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.026
protein polymerization GO:0051258 4 0.026
positive regulation of macromolecule metabolic process GO:0010604 93 0.026
regulation of neuron differentiation GO:0045664 56 0.026
defense response GO:0006952 47 0.025
actin polymerization or depolymerization GO:0008154 2 0.025
regulation of axonogenesis GO:0050770 32 0.025
ear development GO:0043583 127 0.025
brain development GO:0007420 293 0.025
determination of bilateral symmetry GO:0009855 204 0.025
neurotransmitter secretion GO:0007269 2 0.025
response to vitamin GO:0033273 3 0.025
cell projection morphogenesis GO:0048858 244 0.025
system process GO:0003008 185 0.025
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.024
mononuclear cell proliferation GO:0032943 1 0.024
regulation of oocyte development GO:0060281 3 0.024
macromolecule biosynthetic process GO:0009059 227 0.023
striated muscle tissue development GO:0014706 110 0.023
regulation of cell activation GO:0050865 1 0.023
adult behavior GO:0030534 2 0.023
regulation of carbohydrate metabolic process GO:0006109 4 0.023
digestive tract mesoderm development GO:0007502 1 0.023
cellular protein metabolic process GO:0044267 129 0.022
single organism metabolic process GO:0044710 217 0.022
regulation of metal ion transport GO:0010959 4 0.022
regulation of neurotransmitter secretion GO:0046928 1 0.022
regulation of sequestering of calcium ion GO:0051282 4 0.022
cellular response to nutrient levels GO:0031669 2 0.022
response to estrogen GO:0043627 27 0.022
carboxylic acid catabolic process GO:0046395 3 0.022
ossification GO:0001503 23 0.022
carbohydrate derivative metabolic process GO:1901135 61 0.022
response to transition metal nanoparticle GO:1990267 28 0.022
purine nucleoside monophosphate catabolic process GO:0009128 4 0.022
single organism transport GO:0044765 206 0.022
multi organism process GO:0051704 134 0.021
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.021
muscle cell migration GO:0014812 4 0.021
inner ear development GO:0048839 126 0.021
rna metabolic process GO:0016070 219 0.021
regulation of protein transport GO:0051223 3 0.021
cellular response to growth factor stimulus GO:0071363 39 0.021
regulation of cellular ketone metabolic process GO:0010565 7 0.021
negative chemotaxis GO:0050919 1 0.021
response to lipid GO:0033993 60 0.021
regulation of neurogenesis GO:0050767 87 0.021
negative regulation of response to stimulus GO:0048585 104 0.021
negative regulation of metabolic process GO:0009892 86 0.021
regulation of cell size GO:0008361 29 0.021
hematopoietic or lymphoid organ development GO:0048534 191 0.021
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.020
cellular nitrogen compound biosynthetic process GO:0044271 218 0.020
regulation of neurotransmitter transport GO:0051588 1 0.020
regulation of inflammatory response GO:0050727 2 0.020
regulation of biosynthetic process GO:0009889 250 0.020
peptidyl serine modification GO:0018209 2 0.020
blood vessel morphogenesis GO:0048514 216 0.020
secondary metabolic process GO:0019748 3 0.020
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.020
response to organic cyclic compound GO:0014070 51 0.020
heart contraction GO:0060047 71 0.020
regulation of macromolecule biosynthetic process GO:0010556 225 0.020
regulation of transcription dna templated GO:0006355 213 0.020
regulation of developmental growth GO:0048638 38 0.019
negative regulation of gene expression GO:0010629 65 0.019
cellular response to hormone stimulus GO:0032870 39 0.019
gland development GO:0048732 143 0.019
oxidation reduction process GO:0055114 41 0.019
transcription from rna polymerase ii promoter GO:0006366 80 0.019
sequestering of metal ion GO:0051238 3 0.019
regulation of rna metabolic process GO:0051252 224 0.019
guanosine containing compound metabolic process GO:1901068 4 0.019
negative regulation of protein phosphorylation GO:0001933 4 0.019
protein complex biogenesis GO:0070271 30 0.019
positive regulation of developmental process GO:0051094 50 0.018
response to monosaccharide GO:0034284 3 0.018
phagocytosis GO:0006909 3 0.018
regulation of hormone secretion GO:0046883 2 0.018
cellular response to radiation GO:0071478 4 0.018
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.018
determination of heart left right asymmetry GO:0061371 117 0.018
response to oxygen containing compound GO:1901700 55 0.018
peptidyl serine phosphorylation GO:0018105 1 0.018
response to topologically incorrect protein GO:0035966 2 0.018
cellular protein modification process GO:0006464 100 0.018
anterior posterior pattern specification GO:0009952 152 0.018
liver development GO:0001889 96 0.018
regulation of protein polymerization GO:0032271 2 0.018
positive regulation of cellular metabolic process GO:0031325 94 0.018
organic cyclic compound biosynthetic process GO:1901362 223 0.017
protein modification process GO:0036211 100 0.017
regulation of blood vessel size GO:0050880 2 0.017
regulation of phosphorus metabolic process GO:0051174 43 0.017
positive regulation of cell activation GO:0050867 1 0.017
regulation of nucleotide catabolic process GO:0030811 2 0.017
heart looping GO:0001947 94 0.017
transcription dna templated GO:0006351 181 0.017
positive regulation of cell cycle GO:0045787 3 0.017
response to carbohydrate GO:0009743 3 0.017
regulation of sodium ion transport GO:0002028 2 0.017
regulation of axon extension GO:0030516 24 0.017
organic acid catabolic process GO:0016054 3 0.017
b cell mediated immunity GO:0019724 3 0.017
axon development GO:0061564 166 0.016
positive regulation of rna metabolic process GO:0051254 59 0.016
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.016
homeostatic process GO:0042592 142 0.016
neuron development GO:0048666 262 0.016
regulation of gene expression GO:0010468 265 0.016
positive regulation of secretion by cell GO:1903532 1 0.016
regulation of cellular component size GO:0032535 30 0.016
response to glucose GO:0009749 3 0.016
myeloid cell differentiation GO:0030099 86 0.016
actin mediated cell contraction GO:0070252 1 0.015
lymphocyte proliferation GO:0046651 1 0.015
embryonic skeletal system morphogenesis GO:0048704 93 0.015
macromolecular complex assembly GO:0065003 35 0.015
biomineral tissue development GO:0031214 13 0.015
protein complex subunit organization GO:0071822 46 0.015
negative regulation of axon guidance GO:1902668 1 0.015
regulation of nucleic acid templated transcription GO:1903506 213 0.015
monocarboxylic acid catabolic process GO:0072329 3 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.015
production of molecular mediator of immune response GO:0002440 2 0.015
cell proliferation GO:0008283 80 0.015
lipid catabolic process GO:0016042 4 0.015
stem cell proliferation GO:0072089 4 0.015
regulation of ion transmembrane transporter activity GO:0032412 2 0.014
fatty acid oxidation GO:0019395 1 0.014
gastrulation GO:0007369 208 0.014
vasculature development GO:0001944 278 0.014
cranial nerve development GO:0021545 42 0.014
ameboidal type cell migration GO:0001667 143 0.014
regulation of circadian rhythm GO:0042752 4 0.014
blood circulation GO:0008015 87 0.014
circulatory system process GO:0003013 87 0.014
skeletal system morphogenesis GO:0048705 102 0.014
death GO:0016265 121 0.014
regulation of establishment of protein localization GO:0070201 4 0.014
positive regulation of cellular biosynthetic process GO:0031328 68 0.014
embryonic heart tube development GO:0035050 133 0.014
regulation of meiotic cell cycle GO:0051445 1 0.014
gliogenesis GO:0042063 45 0.014
cellular amide metabolic process GO:0043603 4 0.014
positive regulation of secretion GO:0051047 1 0.014
primary neural tube formation GO:0014020 1 0.014
programmed cell death GO:0012501 119 0.014
behavior GO:0007610 74 0.014
regulation of gtp catabolic process GO:0033124 2 0.013
aminoglycan metabolic process GO:0006022 9 0.013
regulation of macromolecule metabolic process GO:0060255 317 0.013
regulation of neuron projection development GO:0010975 40 0.013
stem cell development GO:0048864 82 0.013
positive regulation of cytoskeleton organization GO:0051495 3 0.013
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.013
medulla oblongata development GO:0021550 4 0.013
peptidyl threonine phosphorylation GO:0018107 1 0.013
immune system development GO:0002520 191 0.013
positive regulation of metabolic process GO:0009893 108 0.013
insulin like growth factor receptor signaling pathway GO:0048009 4 0.013
negative regulation of axon extension involved in axon guidance GO:0048843 1 0.013
response to hexose GO:0009746 3 0.013
regulation of cell growth GO:0001558 29 0.013
macromolecule modification GO:0043412 111 0.013
response to fluid shear stress GO:0034405 2 0.013
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.013
positive regulation of endothelial cell proliferation GO:0001938 1 0.013
muscle cell differentiation GO:0042692 139 0.013
embryo development ending in birth or egg hatching GO:0009792 271 0.013
regulation of skeletal muscle tissue development GO:0048641 4 0.013
extracellular matrix organization GO:0030198 27 0.013
digestive system development GO:0055123 289 0.013
phosphate containing compound metabolic process GO:0006796 108 0.013
macromolecular complex subunit organization GO:0043933 74 0.013
leukocyte proliferation GO:0070661 1 0.013
regulation of mrna processing GO:0050684 3 0.013
regulation of protein targeting GO:1903533 2 0.013
meiotic cell cycle process GO:1903046 3 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.012
regulation of cellular component movement GO:0051270 55 0.012
axonal defasciculation GO:0007414 2 0.012
connective tissue development GO:0061448 99 0.012
negative regulation of epithelial cell proliferation GO:0050680 1 0.012
response to ketone GO:1901654 1 0.012
activation of mapk activity GO:0000187 3 0.012
cellular response to extracellular stimulus GO:0031668 2 0.012
regulation of cellular response to growth factor stimulus GO:0090287 35 0.012
regulation of bone mineralization GO:0030500 2 0.012
actin filament polymerization GO:0030041 2 0.012
mesenchymal cell differentiation GO:0048762 87 0.012
negative regulation of developmental process GO:0051093 65 0.012
hepaticobiliary system development GO:0061008 98 0.012
neuron projection morphogenesis GO:0048812 161 0.012
digestive tract morphogenesis GO:0048546 231 0.012
negative regulation of macromolecule metabolic process GO:0010605 76 0.012
maternal determination of anterior posterior axis embryo GO:0008358 4 0.012
negative regulation of cell development GO:0010721 26 0.012
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 22 0.012
organelle assembly GO:0070925 110 0.012
regulation of cellular amine metabolic process GO:0033238 0 0.012
negative regulation of dna metabolic process GO:0051053 4 0.011
protein homooligomerization GO:0051260 3 0.011
positive regulation of gene expression GO:0010628 71 0.011
actin filament based movement GO:0030048 1 0.011
cellular lipid catabolic process GO:0044242 3 0.011
phosphorus metabolic process GO:0006793 109 0.011
convergent extension GO:0060026 118 0.011
negative regulation of cell differentiation GO:0045596 46 0.011
cellular biosynthetic process GO:0044249 286 0.011
positive regulation of nucleoside metabolic process GO:0045979 1 0.011
negative regulation of biosynthetic process GO:0009890 55 0.011
negative regulation of signaling GO:0023057 96 0.011
positive regulation of immune effector process GO:0002699 3 0.011
lamellipodium organization GO:0097581 1 0.011
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.011
stem cell differentiation GO:0048863 117 0.011
regulation of programmed cell death GO:0043067 101 0.011
tissue remodeling GO:0048771 4 0.011
small gtpase mediated signal transduction GO:0007264 8 0.011
exocytosis GO:0006887 1 0.011
gene expression GO:0010467 252 0.011
bmp signaling pathway GO:0030509 52 0.011
cilium assembly GO:0042384 58 0.011
regulation of epithelial to mesenchymal transition GO:0010717 3 0.011
striated muscle cell development GO:0055002 108 0.011
intracellular signal transduction GO:0035556 85 0.011
regulation of molecular function GO:0065009 70 0.011
action potential GO:0001508 19 0.011
positive regulation of apoptotic signaling pathway GO:2001235 1 0.011
regulation of tube size GO:0035150 2 0.011
nuclear import GO:0051170 3 0.011
cellular chemical homeostasis GO:0055082 17 0.011
regulation of anatomical structure size GO:0090066 33 0.011
outflow tract morphogenesis GO:0003151 1 0.011
positive regulation of multicellular organismal process GO:0051240 52 0.011
pathway restricted smad protein phosphorylation GO:0060389 1 0.011
glycoprotein metabolic process GO:0009100 23 0.011
organelle organization GO:0006996 227 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.011
negative regulation of dna replication GO:0008156 2 0.010
positive regulation of epithelial cell proliferation GO:0050679 1 0.010
hormone secretion GO:0046879 2 0.010
embryonic camera type eye development GO:0031076 29 0.010
negative regulation of cellular metabolic process GO:0031324 77 0.010
regulation of circadian sleep wake cycle GO:0042749 1 0.010
camera type eye morphogenesis GO:0048593 108 0.010
regulation of cell death GO:0010941 103 0.010
oocyte maturation GO:0001556 4 0.010
negative regulation of multi organism process GO:0043901 3 0.010
regulation of dna recombination GO:0000018 2 0.010
positive regulation of gtp catabolic process GO:0033126 1 0.010
autophagy GO:0006914 4 0.010
single organism organelle organization GO:1902589 199 0.010
lamellipodium assembly GO:0030032 1 0.010
cell death GO:0008219 121 0.010
positive regulation of cellular amine metabolic process GO:0033240 0 0.010
apoptotic process GO:0006915 116 0.010

thbs3a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.052
musculoskeletal system disease DOID:17 0 0.018
connective tissue disease DOID:65 0 0.018
disease of cellular proliferation DOID:14566 0 0.013
cancer DOID:162 0 0.012
organ system cancer DOID:0050686 0 0.012
nervous system disease DOID:863 0 0.012
myopathy DOID:423 0 0.011
muscular disease DOID:0080000 0 0.011
muscle tissue disease DOID:66 0 0.011