Danio rerio

0 known processes

prpf38b

PRP38 pre-mRNA processing factor 38 (yeast) domain containing B

(Aliases: wu:fc43b05,zgc:63496)

prpf38b biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of gene expression GO:0010468 265 0.402
gene expression GO:0010467 252 0.382
regulation of macromolecule metabolic process GO:0060255 317 0.330
generation of neurons GO:0048699 385 0.302
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.264
larval development GO:0002164 2 0.256
macromolecule biosynthetic process GO:0009059 227 0.248
negative regulation of biological process GO:0048519 304 0.219
regulation of macromolecule biosynthetic process GO:0010556 225 0.216
regulation of metabolic process GO:0019222 359 0.198
regulation of nucleic acid templated transcription GO:1903506 213 0.191
cellular aromatic compound metabolic process GO:0006725 295 0.190
aging GO:0007568 2 0.180
organic cyclic compound metabolic process GO:1901360 301 0.180
regulation of cellular metabolic process GO:0031323 320 0.166
rna biosynthetic process GO:0032774 181 0.156
cellular macromolecule metabolic process GO:0044260 391 0.147
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.146
heterocycle metabolic process GO:0046483 290 0.143
neuron differentiation GO:0030182 353 0.137
regulation of biosynthetic process GO:0009889 250 0.137
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.134
cellular biosynthetic process GO:0044249 286 0.133
cellular macromolecule biosynthetic process GO:0034645 224 0.128
regulation of primary metabolic process GO:0080090 311 0.118
regulation of rna metabolic process GO:0051252 224 0.118
signal transduction GO:0007165 455 0.117
rna metabolic process GO:0016070 219 0.114
cellular nitrogen compound biosynthetic process GO:0044271 218 0.110
neuron projection development GO:0031175 180 0.105
chromosome organization GO:0051276 31 0.096
regulation of cellular biosynthetic process GO:0031326 245 0.094
negative regulation of cellular process GO:0048523 283 0.087
heterocycle biosynthetic process GO:0018130 215 0.083
positive regulation of gene expression GO:0010628 71 0.079
cellular protein catabolic process GO:0044257 4 0.079
cell projection organization GO:0030030 284 0.076
neuron projection morphogenesis GO:0048812 161 0.073
negative regulation of macromolecule metabolic process GO:0010605 76 0.073
positive regulation of biological process GO:0048518 253 0.073
maintenance of location GO:0051235 4 0.071
nucleobase containing compound biosynthetic process GO:0034654 205 0.068
nitrogen compound metabolic process GO:0006807 319 0.067
regulation of rna biosynthetic process GO:2001141 213 0.067
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.065
protein import into nucleus GO:0006606 3 0.064
positive regulation of cellular component biogenesis GO:0044089 3 0.062
regulation of transcription dna templated GO:0006355 213 0.061
negative regulation of developmental process GO:0051093 65 0.061
positive regulation of cellular process GO:0048522 201 0.060
cellular component morphogenesis GO:0032989 336 0.058
organic cyclic compound biosynthetic process GO:1901362 223 0.058
transcription dna templated GO:0006351 181 0.056
regulation of nitrogen compound metabolic process GO:0051171 251 0.056
cellular nitrogen compound metabolic process GO:0034641 290 0.056
regulation of cellular component organization GO:0051128 86 0.055
cell morphogenesis involved in differentiation GO:0000904 195 0.055
localization of cell GO:0051674 244 0.055
positive regulation of macromolecule metabolic process GO:0010604 93 0.055
regulation of chromosome segregation GO:0051983 1 0.053
positive regulation of metabolic process GO:0009893 108 0.052
nucleocytoplasmic transport GO:0006913 4 0.052
cell motility GO:0048870 244 0.050
regulation of establishment of protein localization GO:0070201 4 0.050
cell morphogenesis GO:0000902 289 0.050
nucleobase containing compound metabolic process GO:0006139 274 0.050
negative regulation of biosynthetic process GO:0009890 55 0.049
negative regulation of gene expression GO:0010629 65 0.049
meiotic nuclear division GO:0007126 4 0.049
regulation of multicellular organism growth GO:0040014 4 0.048
biosynthetic process GO:0009058 294 0.048
response to chemical GO:0042221 320 0.048
negative regulation of cellular metabolic process GO:0031324 77 0.046
protein localization to nucleus GO:0034504 3 0.045
locomotor rhythm GO:0045475 3 0.044
negative regulation of nuclear division GO:0051784 3 0.044
stem cell maintenance GO:0019827 4 0.043
blood vessel development GO:0001568 246 0.041
neuron development GO:0048666 262 0.040
regulation of biological quality GO:0065008 263 0.039
single organism organelle organization GO:1902589 199 0.039
regulation of cell communication GO:0010646 232 0.039
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.038
regulation of protein import into nucleus GO:0042306 2 0.038
cognition GO:0050890 1 0.038
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.038
positive regulation of rna metabolic process GO:0051254 59 0.037
axon development GO:0061564 166 0.036
regulation of intracellular protein transport GO:0033157 3 0.036
locomotion GO:0040011 313 0.036
regulation of organelle assembly GO:1902115 4 0.035
internal protein amino acid acetylation GO:0006475 2 0.035
nucleic acid templated transcription GO:0097659 181 0.035
cell migration GO:0016477 237 0.035
aromatic compound biosynthetic process GO:0019438 217 0.035
stem cell proliferation GO:0072089 4 0.035
cellular component movement GO:0006928 335 0.034
response to stress GO:0006950 263 0.034
peptidyl serine modification GO:0018209 2 0.034
internal peptidyl lysine acetylation GO:0018393 2 0.033
nuclear import GO:0051170 3 0.033
establishment of localization GO:0051234 244 0.033
protein targeting to nucleus GO:0044744 3 0.033
cellular response to stress GO:0033554 62 0.032
single organism metabolic process GO:0044710 217 0.032
cell part morphogenesis GO:0032990 246 0.032
dna templated transcription elongation GO:0006354 3 0.032
protein import GO:0017038 3 0.031
cell projection morphogenesis GO:0048858 244 0.031
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.030
macromolecular complex assembly GO:0065003 35 0.030
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.030
chemotaxis GO:0006935 104 0.030
multicellular organism growth GO:0035264 4 0.029
meiotic chromosome segregation GO:0045132 3 0.029
ubiquitin dependent protein catabolic process GO:0006511 3 0.029
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.029
modification dependent protein catabolic process GO:0019941 3 0.029
organelle organization GO:0006996 227 0.028
regionalization GO:0003002 274 0.028
negative regulation of cellular biosynthetic process GO:0031327 55 0.028
regulation of protein transport GO:0051223 3 0.028
regulation of mrna processing GO:0050684 3 0.028
regulation of developmental process GO:0050793 247 0.028
blood vessel morphogenesis GO:0048514 216 0.028
regulation of cell shape GO:0008360 1 0.028
single organism localization GO:1902578 225 0.028
regulation of stem cell proliferation GO:0072091 2 0.027
cellular protein metabolic process GO:0044267 129 0.027
establishment of protein localization to organelle GO:0072594 4 0.027
protein acylation GO:0043543 3 0.027
regulation of cell differentiation GO:0045595 142 0.026
response to external stimulus GO:0009605 264 0.026
negative regulation of cell differentiation GO:0045596 46 0.026
system process GO:0003008 185 0.026
phagocytosis GO:0006909 3 0.026
neurological system process GO:0050877 62 0.026
regulation of response to stimulus GO:0048583 269 0.025
modification dependent macromolecule catabolic process GO:0043632 3 0.025
response to nutrient GO:0007584 3 0.025
cellular macromolecular complex assembly GO:0034622 24 0.025
growth GO:0040007 174 0.025
synaptic growth at neuromuscular junction GO:0051124 2 0.025
amine metabolic process GO:0009308 2 0.025
behavior GO:0007610 74 0.024
peptidyl serine phosphorylation GO:0018105 1 0.024
peptidyl lysine acetylation GO:0018394 2 0.024
death GO:0016265 121 0.024
positive regulation of cellular metabolic process GO:0031325 94 0.024
single organism nuclear import GO:1902593 3 0.024
centrosome organization GO:0051297 1 0.024
transport GO:0006810 220 0.024
regulation of signaling GO:0023051 235 0.024
embryo development ending in birth or egg hatching GO:0009792 271 0.023
organic substance biosynthetic process GO:1901576 289 0.023
cellular amine metabolic process GO:0044106 2 0.023
negative regulation of catabolic process GO:0009895 3 0.023
positive regulation of nucleic acid templated transcription GO:1903508 57 0.022
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.022
positive regulation of transcription dna templated GO:0045893 57 0.022
regulation of multicellular organismal process GO:0051239 277 0.022
cell growth GO:0016049 57 0.022
lipid storage GO:0019915 1 0.022
mrna stabilization GO:0048255 4 0.022
cellular amino acid metabolic process GO:0006520 7 0.022
cytokinesis GO:0000910 3 0.022
cellular response to external stimulus GO:0071496 2 0.022
positive regulation of transport GO:0051050 2 0.022
positive regulation of cellular amine metabolic process GO:0033240 0 0.021
adult behavior GO:0030534 2 0.021
positive regulation of catabolic process GO:0009896 4 0.021
regulation of erk1 and erk2 cascade GO:0070372 4 0.021
negative regulation of intracellular transport GO:0032387 3 0.021
regulation of protein targeting GO:1903533 2 0.021
spliceosomal complex assembly GO:0000245 1 0.021
positive regulation of rna biosynthetic process GO:1902680 57 0.021
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.021
histone h3 k4 methylation GO:0051568 2 0.021
response to organic substance GO:0010033 153 0.020
axonogenesis GO:0007409 152 0.020
regulation of cytokine production GO:0001817 3 0.020
erk1 and erk2 cascade GO:0070371 4 0.020
regulation of cell cycle GO:0051726 52 0.020
immune system process GO:0002376 241 0.020
multi organism cellular process GO:0044764 2 0.020
positive regulation of cellular biosynthetic process GO:0031328 68 0.020
regulation of autophagy GO:0010506 3 0.020
positive regulation of cell cycle GO:0045787 3 0.020
nucleic acid metabolic process GO:0090304 244 0.020
proteasomal protein catabolic process GO:0010498 2 0.020
regulation of protein localization to nucleus GO:1900180 2 0.020
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.020
regulation of protein complex assembly GO:0043254 3 0.019
regulation of synapse organization GO:0050807 3 0.019
protein metabolic process GO:0019538 183 0.019
developmental growth GO:0048589 166 0.019
negative regulation of metabolic process GO:0009892 86 0.019
central nervous system development GO:0007417 387 0.019
nuclear transport GO:0051169 4 0.019
spindle assembly GO:0051225 2 0.019
taxis GO:0042330 109 0.019
cell fate commitment GO:0045165 99 0.018
multi organism process GO:0051704 134 0.018
negative regulation of ras protein signal transduction GO:0046580 1 0.018
protein stabilization GO:0050821 2 0.018
negative regulation of nucleic acid templated transcription GO:1903507 45 0.018
neuron projection guidance GO:0097485 86 0.018
g1 s transition of mitotic cell cycle GO:0000082 1 0.018
developmental growth involved in morphogenesis GO:0060560 86 0.018
regulation of meiotic cell cycle GO:0051445 1 0.018
regulation of localization GO:0032879 104 0.018
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.018
meiosis i GO:0007127 1 0.018
locomotory behavior GO:0007626 34 0.018
centrosome cycle GO:0007098 1 0.018
covalent chromatin modification GO:0016569 20 0.017
negative regulation of cell cycle process GO:0010948 9 0.017
regulation of dna templated transcription elongation GO:0032784 3 0.017
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.017
cell death GO:0008219 121 0.017
microtubule organizing center organization GO:0031023 1 0.017
macromolecular complex subunit organization GO:0043933 74 0.017
extrinsic apoptotic signaling pathway GO:0097191 3 0.017
cellular response to extracellular stimulus GO:0031668 2 0.017
positive regulation of cellular catabolic process GO:0031331 3 0.017
positive regulation of dna templated transcription elongation GO:0032786 1 0.017
brain development GO:0007420 293 0.017
regulation of cellular protein catabolic process GO:1903362 1 0.016
protein modification process GO:0036211 100 0.016
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.016
dorsal ventral pattern formation GO:0009953 125 0.016
regulation of nucleocytoplasmic transport GO:0046822 2 0.016
transcription from rna polymerase ii promoter GO:0006366 80 0.016
b cell activation GO:0042113 2 0.016
cellular protein modification process GO:0006464 100 0.016
heart contraction GO:0060047 71 0.016
chemosensory behavior GO:0007635 1 0.016
macromolecule modification GO:0043412 111 0.016
negative regulation of mitosis GO:0045839 3 0.015
response to external biotic stimulus GO:0043207 97 0.015
intracellular signal transduction GO:0035556 85 0.015
regulation of synapse assembly GO:0051963 3 0.015
protein complex disassembly GO:0043241 1 0.015
skin development GO:0043588 54 0.015
nuclear export GO:0051168 1 0.015
regulation of protein metabolic process GO:0051246 56 0.015
regulation of cytoplasmic transport GO:1903649 4 0.015
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.015
mitochondrion organization GO:0007005 4 0.015
regulation of signal transduction GO:0009966 225 0.015
cellular response to nutrient levels GO:0031669 2 0.014
vasculature development GO:0001944 278 0.014
regulation of circadian rhythm GO:0042752 4 0.014
regulation of reproductive process GO:2000241 4 0.014
interspecies interaction between organisms GO:0044419 4 0.014
ras protein signal transduction GO:0007265 7 0.014
negative regulation of reproductive process GO:2000242 3 0.014
regulation of protein catabolic process GO:0042176 1 0.014
apoptotic process GO:0006915 116 0.014
negative regulation of synapse assembly GO:0051964 2 0.014
dna metabolic process GO:0006259 27 0.014
regulation of stem cell differentiation GO:2000736 4 0.014
regulation of dendrite development GO:0050773 3 0.014
cellular component disassembly GO:0022411 1 0.014
positive regulation of biosynthetic process GO:0009891 68 0.014
stem cell differentiation GO:0048863 117 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.014
negative regulation of programmed cell death GO:0043069 58 0.014
skeletal system development GO:0001501 181 0.014
programmed cell death GO:0012501 119 0.014
carboxylic acid metabolic process GO:0019752 22 0.014
positive regulation of mrna metabolic process GO:1903313 2 0.014
response to uv GO:0009411 3 0.014
cellular component biogenesis GO:0044085 178 0.013
protein acetylation GO:0006473 2 0.013
regulation of nervous system development GO:0051960 90 0.013
response to alkaloid GO:0043279 2 0.013
negative regulation of protein transport GO:0051224 3 0.013
protein polymerization GO:0051258 4 0.013
positive regulation of stem cell proliferation GO:2000648 1 0.013
negative regulation of cytoplasmic transport GO:1903650 2 0.013
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.013
cellular carbohydrate metabolic process GO:0044262 4 0.013
response to radiation GO:0009314 51 0.013
positive regulation of cytokine production GO:0001819 2 0.013
regulation of cellular amine metabolic process GO:0033238 0 0.013
sensory organ development GO:0007423 393 0.013
cytoskeleton organization GO:0007010 96 0.013
macromolecule localization GO:0033036 54 0.013
regulation of mrna splicing via spliceosome GO:0048024 3 0.013
cellular ketone metabolic process GO:0042180 11 0.012
head development GO:0060322 303 0.012
negative regulation of dna replication GO:0008156 2 0.012
regulation of microtubule cytoskeleton organization GO:0070507 3 0.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.012
regulation of mitosis GO:0007088 9 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.012
axon extension GO:0048675 45 0.012
mitotic g2 dna damage checkpoint GO:0007095 3 0.012
cellular response to starvation GO:0009267 1 0.012
cellular component assembly GO:0022607 170 0.012
sex determination GO:0007530 1 0.012
mitotic cytokinesis GO:0000281 3 0.012
neuroblast proliferation GO:0007405 2 0.012
negative regulation of transcription dna templated GO:0045892 45 0.012
cellular response to chemical stimulus GO:0070887 157 0.012
g2 m transition of mitotic cell cycle GO:0000086 4 0.012
reproduction GO:0000003 40 0.012
cilium morphogenesis GO:0060271 85 0.012
autophagy GO:0006914 4 0.012
response to biotic stimulus GO:0009607 97 0.012
single organism reproductive process GO:0044702 40 0.012
mitotic sister chromatid segregation GO:0000070 6 0.012
single organism cellular localization GO:1902580 46 0.012
cardiac atrium development GO:0003230 4 0.012
regulation of cell death GO:0010941 103 0.012
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.012
male meiosis GO:0007140 2 0.011
regulation of organelle organization GO:0033043 29 0.011
intracellular receptor signaling pathway GO:0030522 30 0.011
leukocyte proliferation GO:0070661 1 0.011
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.011
regulation of wnt signaling pathway GO:0030111 53 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
translational initiation GO:0006413 3 0.011
cellular response to radiation GO:0071478 4 0.011
intracellular estrogen receptor signaling pathway GO:0030520 3 0.011
regulation of inflammatory response GO:0050727 2 0.011
protein polyubiquitination GO:0000209 4 0.011
protein complex localization GO:0031503 1 0.011
regulation of gene expression epigenetic GO:0040029 11 0.011
positive regulation of cytoskeleton organization GO:0051495 3 0.011
rna 3 end processing GO:0031123 2 0.011
negative regulation of multi organism process GO:0043901 3 0.011
viral process GO:0016032 1 0.011
cytoskeleton dependent cytokinesis GO:0061640 3 0.011
regulation of response to extracellular stimulus GO:0032104 1 0.011
negative regulation of intracellular protein transport GO:0090317 3 0.011
positive regulation of histone modification GO:0031058 1 0.011
positive regulation of immune effector process GO:0002699 3 0.011
negative regulation of multicellular organismal process GO:0051241 69 0.011
angiogenesis GO:0001525 158 0.011
negative regulation of cell communication GO:0010648 96 0.011
muscle organ development GO:0007517 101 0.011
negative regulation of translation GO:0017148 1 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.011
negative regulation of chromosome organization GO:2001251 1 0.011
meiotic cell cycle process GO:1903046 3 0.011
rna localization GO:0006403 4 0.011
negative regulation of rna biosynthetic process GO:1902679 45 0.011
regulation of purine nucleotide catabolic process GO:0033121 2 0.011
regulation of cellular ketone metabolic process GO:0010565 7 0.011
regulation of cellular protein metabolic process GO:0032268 52 0.011
i kappab kinase nf kappab signaling GO:0007249 4 0.010
compound eye development GO:0048749 2 0.010
female gonad development GO:0008585 4 0.010
mrna processing GO:0006397 14 0.010
oxoacid metabolic process GO:0043436 31 0.010
regulation of mitotic cell cycle GO:0007346 25 0.010
cell surface receptor signaling pathway GO:0007166 325 0.010
regulation of cell development GO:0060284 100 0.010
regulation of cell activation GO:0050865 1 0.010
cell cycle arrest GO:0007050 1 0.010
negative regulation of cellular catabolic process GO:0031330 3 0.010
lymphocyte proliferation GO:0046651 1 0.010
circulatory system process GO:0003013 87 0.010

prpf38b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.031
cancer DOID:162 0 0.018
disease of cellular proliferation DOID:14566 0 0.018
organ system cancer DOID:0050686 0 0.018
muscular disease DOID:0080000 0 0.012
musculoskeletal system disease DOID:17 0 0.012
muscle tissue disease DOID:66 0 0.012
nervous system disease DOID:863 0 0.012