Danio rerio

0 known processes

gldc

glycine dehydrogenase (decarboxylating)

(Aliases: wu:fb23b05,zgc:66198,fb23b05)

gldc biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
aging GO:0007568 2 0.095
adult behavior GO:0030534 2 0.066
single organism transport GO:0044765 206 0.048
multicellular organism growth GO:0035264 4 0.048
larval development GO:0002164 2 0.045
extrinsic apoptotic signaling pathway GO:0097191 3 0.045
sensory organ development GO:0007423 393 0.045
cognition GO:0050890 1 0.044
nitrogen compound metabolic process GO:0006807 319 0.044
locomotion GO:0040011 313 0.044
regulation of multicellular organism growth GO:0040014 4 0.043
nuclear transport GO:0051169 4 0.043
cellular ketone metabolic process GO:0042180 11 0.043
amine metabolic process GO:0009308 2 0.042
single organism organelle organization GO:1902589 199 0.040
cell morphogenesis GO:0000902 289 0.040
nucleocytoplasmic transport GO:0006913 4 0.039
cell projection morphogenesis GO:0048858 244 0.039
cellular component morphogenesis GO:0032989 336 0.037
phagocytosis GO:0006909 3 0.036
response to chemical GO:0042221 320 0.036
positive regulation of protein complex assembly GO:0031334 2 0.035
morphogenesis of an epithelium GO:0002009 333 0.034
maintenance of location GO:0051235 4 0.034
nuclear import GO:0051170 3 0.033
lipid storage GO:0019915 1 0.033
single organism nuclear import GO:1902593 3 0.033
oxoacid metabolic process GO:0043436 31 0.032
positive regulation of catabolic process GO:0009896 4 0.032
cell surface receptor signaling pathway GO:0007166 325 0.032
organic substance biosynthetic process GO:1901576 289 0.032
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.032
brain development GO:0007420 293 0.032
protein localization to nucleus GO:0034504 3 0.032
signal transduction GO:0007165 455 0.031
positive regulation of cellular component biogenesis GO:0044089 3 0.030
protein targeting to nucleus GO:0044744 3 0.030
regulation of circadian rhythm GO:0042752 4 0.030
small molecule metabolic process GO:0044281 77 0.030
cell projection organization GO:0030030 284 0.030
cellular amine metabolic process GO:0044106 2 0.029
establishment of localization GO:0051234 244 0.029
establishment of protein localization to organelle GO:0072594 4 0.029
organic acid metabolic process GO:0006082 31 0.029
cell part morphogenesis GO:0032990 246 0.029
central nervous system development GO:0007417 387 0.028
generation of neurons GO:0048699 385 0.028
positive regulation of cellular catabolic process GO:0031331 3 0.028
eye development GO:0001654 277 0.028
regulation of cellular amine metabolic process GO:0033238 0 0.028
regulation of protein ubiquitination GO:0031396 3 0.028
regulation of protein complex assembly GO:0043254 3 0.027
head development GO:0060322 303 0.027
positive regulation of transport GO:0051050 2 0.027
single organism localization GO:1902578 225 0.027
transport GO:0006810 220 0.027
response to nutrient GO:0007584 3 0.026
biosynthetic process GO:0009058 294 0.026
centrosome cycle GO:0007098 1 0.026
cellular component assembly GO:0022607 170 0.026
autophagy GO:0006914 4 0.026
regionalization GO:0003002 274 0.026
camera type eye development GO:0043010 222 0.026
digestive system development GO:0055123 289 0.026
regulation of cellular amino acid metabolic process GO:0006521 0 0.025
protein import GO:0017038 3 0.025
response to organic substance GO:0010033 153 0.025
cellular macromolecule metabolic process GO:0044260 391 0.025
regulation of multicellular organismal process GO:0051239 277 0.025
chemosensory behavior GO:0007635 1 0.025
embryonic organ development GO:0048568 381 0.025
stem cell maintenance GO:0019827 4 0.025
protein import into nucleus GO:0006606 3 0.024
neuron development GO:0048666 262 0.024
regulation of cellular ketone metabolic process GO:0010565 7 0.024
chordate embryonic development GO:0043009 271 0.024
carboxylic acid metabolic process GO:0019752 22 0.024
cellular biosynthetic process GO:0044249 286 0.024
anterior posterior pattern specification GO:0009952 152 0.024
ameboidal type cell migration GO:0001667 143 0.023
regulation of response to stimulus GO:0048583 269 0.023
cellular protein catabolic process GO:0044257 4 0.023
regulation of cell communication GO:0010646 232 0.023
response to external stimulus GO:0009605 264 0.023
single organism metabolic process GO:0044710 217 0.023
regulation of dendrite development GO:0050773 3 0.023
neuron differentiation GO:0030182 353 0.023
proteasomal protein catabolic process GO:0010498 2 0.023
guanosine containing compound metabolic process GO:1901068 4 0.022
stem cell proliferation GO:0072089 4 0.022
microtubule organizing center organization GO:0031023 1 0.022
convergent extension GO:0060026 118 0.022
developmental growth GO:0048589 166 0.022
golgi vesicle transport GO:0048193 3 0.022
centrosome organization GO:0051297 1 0.022
cellular amino acid metabolic process GO:0006520 7 0.021
gene expression GO:0010467 252 0.021
regulation of protein catabolic process GO:0042176 1 0.021
aromatic compound biosynthetic process GO:0019438 217 0.021
negative regulation of protein phosphorylation GO:0001933 4 0.021
lipid catabolic process GO:0016042 4 0.021
cellular carbohydrate metabolic process GO:0044262 4 0.021
cellular aromatic compound metabolic process GO:0006725 295 0.021
regulation of metal ion transport GO:0010959 4 0.021
system process GO:0003008 185 0.021
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.021
response to stress GO:0006950 263 0.021
cellular component movement GO:0006928 335 0.020
tube morphogenesis GO:0035239 349 0.020
internal protein amino acid acetylation GO:0006475 2 0.020
growth GO:0040007 174 0.020
guanosine containing compound catabolic process GO:1901069 2 0.020
ribonucleoside monophosphate catabolic process GO:0009158 4 0.020
digestive tract development GO:0048565 265 0.020
lateral inhibition GO:0046331 1 0.020
response to abiotic stimulus GO:0009628 122 0.020
regulation of signal transduction GO:0009966 225 0.020
regulation of establishment of protein localization GO:0070201 4 0.020
positive regulation of apoptotic signaling pathway GO:2001235 1 0.020
negative regulation of protein complex assembly GO:0031333 1 0.020
regulation of macromolecule metabolic process GO:0060255 317 0.019
protein dephosphorylation GO:0006470 3 0.019
positive regulation of cellular amine metabolic process GO:0033240 0 0.019
gtp catabolic process GO:0006184 2 0.019
signal transduction in absence of ligand GO:0038034 1 0.019
dicarboxylic acid transport GO:0006835 1 0.019
cellular response to external stimulus GO:0071496 2 0.019
immune system process GO:0002376 241 0.019
regulation of cell shape GO:0008360 1 0.019
protein homooligomerization GO:0051260 3 0.019
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.019
nuclear export GO:0051168 1 0.019
response to corticosteroid GO:0031960 1 0.019
positive regulation of dna metabolic process GO:0051054 1 0.019
enzyme linked receptor protein signaling pathway GO:0007167 106 0.019
hemopoiesis GO:0030097 183 0.019
mitochondrion organization GO:0007005 4 0.019
regulation of signaling GO:0023051 235 0.019
protein polyubiquitination GO:0000209 4 0.019
regulation of binding GO:0051098 3 0.018
regulation of stem cell proliferation GO:0072091 2 0.018
heart development GO:0007507 313 0.018
protein polymerization GO:0051258 4 0.018
synaptic growth at neuromuscular junction GO:0051124 2 0.018
regulation of cellular biosynthetic process GO:0031326 245 0.018
protein heterooligomerization GO:0051291 1 0.018
cell substrate adhesion GO:0031589 4 0.018
rna metabolic process GO:0016070 219 0.018
rna biosynthetic process GO:0032774 181 0.018
regulation of biological quality GO:0065008 263 0.018
atp catabolic process GO:0006200 4 0.018
cellular component disassembly GO:0022411 1 0.018
nucleoside monophosphate catabolic process GO:0009125 4 0.018
immune system development GO:0002520 191 0.018
modification dependent macromolecule catabolic process GO:0043632 3 0.018
wnt signaling pathway GO:0016055 80 0.018
cellular lipid catabolic process GO:0044242 3 0.018
regulation of response to nutrient levels GO:0032107 1 0.018
response to drug GO:0042493 3 0.018
negative regulation of mitosis GO:0045839 3 0.018
modification dependent protein catabolic process GO:0019941 3 0.018
response to glucocorticoid GO:0051384 1 0.018
muscle structure development GO:0061061 196 0.017
secondary metabolic process GO:0019748 3 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.017
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.017
organonitrogen compound metabolic process GO:1901564 74 0.017
meiotic cell cycle process GO:1903046 3 0.017
cellular response to chemical stimulus GO:0070887 157 0.017
heterocycle metabolic process GO:0046483 290 0.017
gland development GO:0048732 143 0.017
ubiquitin dependent protein catabolic process GO:0006511 3 0.017
gtp metabolic process GO:0046039 4 0.017
heterocycle biosynthetic process GO:0018130 215 0.017
regulation of cellular metabolic process GO:0031323 320 0.017
organic cyclic compound biosynthetic process GO:1901362 223 0.017
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.017
regulation of cytoplasmic transport GO:1903649 4 0.017
organic cyclic compound metabolic process GO:1901360 301 0.016
regulation of biosynthetic process GO:0009889 250 0.016
cellular macromolecule biosynthetic process GO:0034645 224 0.016
peptidyl lysine acetylation GO:0018394 2 0.016
small molecule catabolic process GO:0044282 3 0.016
embryonic limb morphogenesis GO:0030326 2 0.016
regulation of protein targeting GO:1903533 2 0.016
neurotransmitter transport GO:0006836 2 0.016
cellular response to extracellular stimulus GO:0031668 2 0.016
negative regulation of protein kinase activity GO:0006469 4 0.016
cellular nitrogen compound biosynthetic process GO:0044271 218 0.016
neuron projection development GO:0031175 180 0.016
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.016
regulation of protein transport GO:0051223 3 0.016
regulation of cell activation GO:0050865 1 0.016
regulation of purine nucleotide catabolic process GO:0033121 2 0.016
localization of cell GO:0051674 244 0.016
meiotic nuclear division GO:0007126 4 0.016
cellular respiration GO:0045333 3 0.016
negative regulation of cell communication GO:0010648 96 0.016
positive regulation of gtp catabolic process GO:0033126 1 0.016
negative regulation of kinase activity GO:0033673 4 0.016
g1 s transition of mitotic cell cycle GO:0000082 1 0.016
regulation of dendrite morphogenesis GO:0048814 3 0.016
hepaticobiliary system development GO:0061008 98 0.015
cell migration GO:0016477 237 0.015
neurotransmitter secretion GO:0007269 2 0.015
segmentation GO:0035282 97 0.015
regulation of nucleotide catabolic process GO:0030811 2 0.015
regulation of nucleoside metabolic process GO:0009118 2 0.015
regulation of synapse organization GO:0050807 3 0.015
hematopoietic or lymphoid organ development GO:0048534 191 0.015
internal peptidyl lysine acetylation GO:0018393 2 0.015
tube closure GO:0060606 1 0.015
cell matrix adhesion GO:0007160 4 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.015
regulation of protein polymerization GO:0032271 2 0.015
regulation of synapse assembly GO:0051963 3 0.015
positive regulation of protein polymerization GO:0032273 2 0.015
cellular amide metabolic process GO:0043603 4 0.015
negative regulation of nuclear division GO:0051784 3 0.015
centrosome duplication GO:0051298 1 0.015
regulation of cytokine production GO:0001817 3 0.015
cellular nitrogen compound metabolic process GO:0034641 290 0.015
cellular response to oxygen levels GO:0071453 1 0.015
organelle fusion GO:0048284 3 0.014
protein acylation GO:0043543 3 0.014
cilium organization GO:0044782 71 0.014
organelle organization GO:0006996 227 0.014
regulation of metabolic process GO:0019222 359 0.014
positive regulation of nucleoside metabolic process GO:0045979 1 0.014
response to endogenous stimulus GO:0009719 83 0.014
regulation of nucleocytoplasmic transport GO:0046822 2 0.014
negative regulation of signaling GO:0023057 96 0.014
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.014
response to vitamin GO:0033273 3 0.014
regulation of anatomical structure morphogenesis GO:0022603 130 0.014
cilium morphogenesis GO:0060271 85 0.014
hormone secretion GO:0046879 2 0.014
digestive tract morphogenesis GO:0048546 231 0.014
apoptotic process involved in development GO:1902742 2 0.014
response to carbohydrate GO:0009743 3 0.014
cellular response to nutrient levels GO:0031669 2 0.014
protein metabolic process GO:0019538 183 0.014
membrane invagination GO:0010324 1 0.014
embryo development ending in birth or egg hatching GO:0009792 271 0.014
sensory organ morphogenesis GO:0090596 200 0.014
primary neural tube formation GO:0014020 1 0.014
regulation of blood pressure GO:0008217 1 0.014
macromolecule biosynthetic process GO:0009059 227 0.014
protein stabilization GO:0050821 2 0.014
nucleobase containing compound metabolic process GO:0006139 274 0.014
negative regulation of cellular process GO:0048523 283 0.014
cilium assembly GO:0042384 58 0.013
cell aging GO:0007569 2 0.013
energy reserve metabolic process GO:0006112 2 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.013
cellular component biogenesis GO:0044085 178 0.013
protein complex disassembly GO:0043241 1 0.013
vasculature development GO:0001944 278 0.013
b cell activation GO:0042113 2 0.013
regulation of tube size GO:0035150 2 0.013
regulation of protein import into nucleus GO:0042306 2 0.013
cellular response to starvation GO:0009267 1 0.013
protein acetylation GO:0006473 2 0.013
regulation of carbohydrate metabolic process GO:0006109 4 0.013
positive regulation of nucleotide catabolic process GO:0030813 1 0.013
nucleic acid metabolic process GO:0090304 244 0.013
endocrine process GO:0050886 2 0.013
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.013
homeostatic process GO:0042592 142 0.013
gastrulation GO:0007369 208 0.013
sleep GO:0030431 1 0.013
nucleobase containing compound biosynthetic process GO:0034654 205 0.013
positive regulation of cell activation GO:0050867 1 0.013
regulation of nitrogen compound metabolic process GO:0051171 251 0.013
negative regulation of cytoplasmic transport GO:1903650 2 0.013
regulation of autophagy GO:0010506 3 0.013
regulation of jak stat cascade GO:0046425 3 0.013
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.013
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.013
regulation of gene expression GO:0010468 265 0.013
protein modification process GO:0036211 100 0.013
cell cycle g1 s phase transition GO:0044843 1 0.013
cell morphogenesis involved in differentiation GO:0000904 195 0.013
response to glucose GO:0009749 3 0.013
transcription dna templated GO:0006351 181 0.013
somite development GO:0061053 96 0.013
macromolecular complex disassembly GO:0032984 1 0.013
positive regulation of gtpase activity GO:0043547 1 0.012
actin polymerization or depolymerization GO:0008154 2 0.012
adherens junction organization GO:0034332 4 0.012
cellular transition metal ion homeostasis GO:0046916 3 0.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.012
multi organism process GO:0051704 134 0.012
regulation of gtpase activity GO:0043087 2 0.012
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.012
developmental programmed cell death GO:0010623 4 0.012
macromolecular complex subunit organization GO:0043933 74 0.012
alpha amino acid metabolic process GO:1901605 3 0.012
angiogenesis GO:0001525 158 0.012
peptide transport GO:0015833 1 0.012
establishment of synaptic vesicle localization GO:0097480 1 0.012
tissue remodeling GO:0048771 4 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.012
negative regulation of signal transduction GO:0009968 94 0.012
glucose homeostasis GO:0042593 1 0.012
regulation of dna replication GO:0006275 3 0.012
regulation of gtp catabolic process GO:0033124 2 0.012
positive regulation of cytoskeleton organization GO:0051495 3 0.012
regulation of organ growth GO:0046620 3 0.012
positive regulation of biological process GO:0048518 253 0.012
cellular response to hypoxia GO:0071456 1 0.012
regulation of protein localization to nucleus GO:1900180 2 0.012
response to biotic stimulus GO:0009607 97 0.012
peptidyl serine phosphorylation GO:0018105 1 0.012
negative regulation of intracellular transport GO:0032387 3 0.012
positive regulation of map kinase activity GO:0043406 3 0.012
lymphocyte proliferation GO:0046651 1 0.012
negative regulation of catabolic process GO:0009895 3 0.012
locomotor rhythm GO:0045475 3 0.012
regulation of rna metabolic process GO:0051252 224 0.012
cellular response to decreased oxygen levels GO:0036294 1 0.012
actin filament polymerization GO:0030041 2 0.012
determination of bilateral symmetry GO:0009855 204 0.011
positive regulation of cell cycle GO:0045787 3 0.011
regulation of response to extracellular stimulus GO:0032104 1 0.011
regulation of epithelial cell proliferation GO:0050678 3 0.011
mononuclear cell proliferation GO:0032943 1 0.011
peptide metabolic process GO:0006518 1 0.011
blood vessel development GO:0001568 246 0.011
somatic muscle development GO:0007525 4 0.011
cellular component assembly involved in morphogenesis GO:0010927 107 0.011
dorsal ventral pattern formation GO:0009953 125 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.011
regulation of intracellular protein transport GO:0033157 3 0.011
transcription from rna polymerase ii promoter GO:0006366 80 0.011
negative chemotaxis GO:0050919 1 0.011
post embryonic organ development GO:0048569 4 0.011
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.011
mesenchyme development GO:0060485 127 0.011
cytokinesis GO:0000910 3 0.011
liver development GO:0001889 96 0.011
positive regulation of secretion GO:0051047 1 0.011
negative regulation of macromolecule metabolic process GO:0010605 76 0.011
carbohydrate biosynthetic process GO:0016051 1 0.011
fatty acid catabolic process GO:0009062 1 0.011
alcohol biosynthetic process GO:0046165 2 0.011
regulation of erk1 and erk2 cascade GO:0070372 4 0.011
er to golgi vesicle mediated transport GO:0006888 1 0.011
negative regulation of secretion by cell GO:1903531 2 0.011
synaptic vesicle localization GO:0097479 1 0.011
sequestering of calcium ion GO:0051208 3 0.011
single organism membrane fusion GO:0044801 2 0.011
cellular response to radiation GO:0071478 4 0.011
rna localization GO:0006403 4 0.011
carbohydrate homeostasis GO:0033500 1 0.011
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.011
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.011
organic acid catabolic process GO:0016054 3 0.011
embryonic organ morphogenesis GO:0048562 274 0.011
endocrine hormone secretion GO:0060986 2 0.011
response to alkaloid GO:0043279 2 0.011
negative regulation of response to stimulus GO:0048585 104 0.011
erk1 and erk2 cascade GO:0070371 4 0.011
response to hexose GO:0009746 3 0.011
skeletal system development GO:0001501 181 0.011
negative regulation of protein transport GO:0051224 3 0.011
spermatid differentiation GO:0048515 2 0.011
regulation of primary metabolic process GO:0080090 311 0.011
sensory perception of pain GO:0019233 1 0.011
epithelial cell differentiation GO:0030855 116 0.011
actin filament based movement GO:0030048 1 0.011
estrogen metabolic process GO:0008210 2 0.011
regulation of blood vessel size GO:0050880 2 0.011
cartilage development GO:0051216 96 0.011
negative regulation of synapse assembly GO:0051964 2 0.011
entrainment of circadian clock GO:0009649 2 0.011
regulation of protein binding GO:0043393 3 0.011
response to uv GO:0009411 3 0.011
response to external biotic stimulus GO:0043207 97 0.011
regulation of hormone secretion GO:0046883 2 0.011
macroautophagy GO:0016236 1 0.011
regulation of neural precursor cell proliferation GO:2000177 3 0.011
single fertilization GO:0007338 3 0.011
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.011
osteoclast differentiation GO:0030316 1 0.011
negative regulation of sequestering of calcium ion GO:0051283 4 0.011
regulation of receptor activity GO:0010469 2 0.010
response to monosaccharide GO:0034284 3 0.010
positive regulation of chromosome organization GO:2001252 1 0.010
cytoskeleton dependent cytokinesis GO:0061640 3 0.010
synaptic vesicle transport GO:0048489 1 0.010
regulation of stem cell differentiation GO:2000736 4 0.010
regulation of cell substrate adhesion GO:0010810 1 0.010
phototransduction GO:0007602 2 0.010
cellular aldehyde metabolic process GO:0006081 4 0.010
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.010
cell projection assembly GO:0030031 64 0.010
cellular protein metabolic process GO:0044267 129 0.010
regulation of reproductive process GO:2000241 4 0.010
regulation of transcription dna templated GO:0006355 213 0.010
neuroblast proliferation GO:0007405 2 0.010
mitotic dna integrity checkpoint GO:0044774 4 0.010
blood vessel morphogenesis GO:0048514 216 0.010
positive regulation of notch signaling pathway GO:0045747 3 0.010
positive regulation of chromatin modification GO:1903310 1 0.010
type b pancreatic cell development GO:0003323 4 0.010
steroid hormone secretion GO:0035929 1 0.010
compound eye development GO:0048749 2 0.010
negative regulation of metabolic process GO:0009892 86 0.010
negative regulation of cellular catabolic process GO:0031330 3 0.010
positive regulation of lipid metabolic process GO:0045834 1 0.010
death GO:0016265 121 0.010
epithelial cell morphogenesis GO:0003382 2 0.010
pancreas development GO:0031016 84 0.010

gldc disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.046
disease of metabolism DOID:0014667 0 0.029
inherited metabolic disorder DOID:655 0 0.029
musculoskeletal system disease DOID:17 0 0.019
nervous system disease DOID:863 0 0.019
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
organ system cancer DOID:0050686 0 0.014
immune system disease DOID:2914 0 0.013
lysosomal storage disease DOID:3211 0 0.011