Danio rerio

0 known processes

s100z

S100 calcium binding protein Z

(Aliases: wu:fj01a12,zgc:110464)

s100z biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
negative regulation of cell cell adhesion mediated by cadherin GO:2000048 2 0.265
signal transduction GO:0007165 455 0.177
nuclear transport GO:0051169 4 0.166
nucleocytoplasmic transport GO:0006913 4 0.117
regulation of primary metabolic process GO:0080090 311 0.106
heart development GO:0007507 313 0.105
establishment of endothelial barrier GO:0061028 3 0.077
guanosine containing compound metabolic process GO:1901068 4 0.076
nucleobase containing compound metabolic process GO:0006139 274 0.075
hematopoietic or lymphoid organ development GO:0048534 191 0.072
regulation of nucleotide catabolic process GO:0030811 2 0.071
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.070
gtp catabolic process GO:0006184 2 0.068
hemopoiesis GO:0030097 183 0.066
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.066
gtp metabolic process GO:0046039 4 0.065
guanosine containing compound catabolic process GO:1901069 2 0.064
regulation of gtp catabolic process GO:0033124 2 0.064
digestive tract development GO:0048565 265 0.063
head development GO:0060322 303 0.063
digestive system development GO:0055123 289 0.063
detection of external stimulus GO:0009581 24 0.060
regulation of nucleocytoplasmic transport GO:0046822 2 0.058
nitrogen compound metabolic process GO:0006807 319 0.055
blood vessel development GO:0001568 246 0.054
system process GO:0003008 185 0.053
g protein coupled receptor signaling pathway GO:0007186 74 0.052
regulation of gtpase activity GO:0043087 2 0.052
ameboidal type cell migration GO:0001667 143 0.052
regulation of nucleoside metabolic process GO:0009118 2 0.052
purine nucleotide metabolic process GO:0006163 27 0.051
immune system development GO:0002520 191 0.051
regulation of protein complex assembly GO:0043254 3 0.050
cellular component assembly GO:0022607 170 0.048
detection of abiotic stimulus GO:0009582 24 0.048
positive regulation of cellular component biogenesis GO:0044089 3 0.047
regulation of skeletal muscle tissue development GO:0048641 4 0.046
positive regulation of cytoskeleton organization GO:0051495 3 0.045
gastrulation GO:0007369 208 0.044
angiogenesis GO:0001525 158 0.044
neurological system process GO:0050877 62 0.044
positive regulation of cellular catabolic process GO:0031331 3 0.044
morphogenesis of an epithelium GO:0002009 333 0.043
nuclear export GO:0051168 1 0.043
regulation of nitrogen compound metabolic process GO:0051171 251 0.042
positive regulation of catabolic process GO:0009896 4 0.042
cell motility GO:0048870 244 0.042
regulation of cytoplasmic transport GO:1903649 4 0.042
detection of visible light GO:0009584 12 0.041
rho protein signal transduction GO:0007266 5 0.041
positive regulation of nucleoside metabolic process GO:0045979 1 0.041
actomyosin structure organization GO:0031032 53 0.041
axon ensheathment in central nervous system GO:0032291 2 0.041
tube morphogenesis GO:0035239 349 0.040
regulation of rho protein signal transduction GO:0035023 2 0.040
regulation of cell cell adhesion mediated by cadherin GO:2000047 5 0.040
regulation of metabolic process GO:0019222 359 0.040
positive regulation of gtpase activity GO:0043547 1 0.039
small gtpase mediated signal transduction GO:0007264 8 0.039
regulation of cell shape GO:0008360 1 0.039
regulation of establishment of protein localization GO:0070201 4 0.038
response to drug GO:0042493 3 0.038
regulation of intracellular protein transport GO:0033157 3 0.037
aging GO:0007568 2 0.036
regulation of protein transport GO:0051223 3 0.036
establishment of protein localization to plasma membrane GO:0090002 1 0.036
positive regulation of nucleotide catabolic process GO:0030813 1 0.036
cell migration GO:0016477 237 0.035
positive regulation of biological process GO:0048518 253 0.035
establishment of blood brain barrier GO:0060856 2 0.034
cell migration involved in heart development GO:0060973 22 0.034
phosphorus metabolic process GO:0006793 109 0.034
cellular aromatic compound metabolic process GO:0006725 295 0.034
single organism metabolic process GO:0044710 217 0.033
epithelial cell differentiation GO:0030855 116 0.033
organic cyclic compound metabolic process GO:1901360 301 0.033
protein heterooligomerization GO:0051291 1 0.033
aromatic compound biosynthetic process GO:0019438 217 0.033
regulation of gene expression GO:0010468 265 0.033
detection of light stimulus involved in sensory perception GO:0050962 7 0.032
cell morphogenesis GO:0000902 289 0.032
nuclear import GO:0051170 3 0.032
protein localization to nucleus GO:0034504 3 0.032
vasculature development GO:0001944 278 0.031
positive regulation of cellular process GO:0048522 201 0.031
establishment of protein localization to organelle GO:0072594 4 0.031
digestive tract morphogenesis GO:0048546 231 0.031
regulation of synaptic plasticity GO:0048167 1 0.030
adherens junction organization GO:0034332 4 0.030
response to abiotic stimulus GO:0009628 122 0.030
blood vessel morphogenesis GO:0048514 216 0.030
cell surface receptor signaling pathway GO:0007166 325 0.029
response to chemical GO:0042221 320 0.029
cellular nitrogen compound metabolic process GO:0034641 290 0.028
immune system process GO:0002376 241 0.028
reactive oxygen species biosynthetic process GO:1903409 1 0.028
organonitrogen compound metabolic process GO:1901564 74 0.028
regulation of binding GO:0051098 3 0.028
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.028
fertilization GO:0009566 3 0.028
muscle organ development GO:0007517 101 0.027
stem cell proliferation GO:0072089 4 0.027
biosynthetic process GO:0009058 294 0.027
phototransduction GO:0007602 2 0.027
negative regulation of protein phosphorylation GO:0001933 4 0.027
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.027
organic cyclic compound biosynthetic process GO:1901362 223 0.027
negative regulation of cellular process GO:0048523 283 0.026
synaptic growth at neuromuscular junction GO:0051124 2 0.026
cellular component morphogenesis GO:0032989 336 0.025
gene expression GO:0010467 252 0.025
reactive nitrogen species metabolic process GO:2001057 0 0.025
cellular macromolecule metabolic process GO:0044260 391 0.025
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.024
response to light stimulus GO:0009416 46 0.024
single organism localization GO:1902578 225 0.024
negative regulation of biological process GO:0048519 304 0.024
circulatory system process GO:0003013 87 0.024
regulation of rna metabolic process GO:0051252 224 0.024
larval development GO:0002164 2 0.024
cellular nitrogen compound biosynthetic process GO:0044271 218 0.024
regulation of intracellular signal transduction GO:1902531 57 0.023
detection of light stimulus GO:0009583 12 0.023
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 2 0.023
actin filament based process GO:0030029 64 0.023
pole plasm assembly GO:0007315 4 0.023
protein localization to plasma membrane GO:0072659 1 0.023
small molecule metabolic process GO:0044281 77 0.023
cell migration involved in gastrulation GO:0042074 79 0.023
nitric oxide metabolic process GO:0046209 2 0.023
detection of stimulus GO:0051606 29 0.023
transport GO:0006810 220 0.023
regulation of reproductive process GO:2000241 4 0.023
sensory perception of smell GO:0007608 2 0.022
positive regulation of gtp catabolic process GO:0033126 1 0.022
regulation of purine nucleotide catabolic process GO:0033121 2 0.021
developmental growth involved in morphogenesis GO:0060560 86 0.021
nuclear migration GO:0007097 3 0.021
ribonucleotide metabolic process GO:0009259 27 0.021
cellular component biogenesis GO:0044085 178 0.021
heterocycle metabolic process GO:0046483 290 0.021
heart process GO:0003015 71 0.021
regulation of synapse organization GO:0050807 3 0.020
response to glucocorticoid GO:0051384 1 0.020
ras protein signal transduction GO:0007265 7 0.020
nitric oxide biosynthetic process GO:0006809 2 0.020
stem cell division GO:0017145 1 0.020
neuroblast proliferation GO:0007405 2 0.020
regulation of rna biosynthetic process GO:2001141 213 0.020
regulation of reactive oxygen species metabolic process GO:2000377 2 0.020
regulation of cell communication GO:0010646 232 0.020
single organism organelle organization GO:1902589 199 0.020
growth GO:0040007 174 0.020
protein import GO:0017038 3 0.020
intracellular signal transduction GO:0035556 85 0.020
response to external stimulus GO:0009605 264 0.020
regulation of biological quality GO:0065008 263 0.020
establishment of localization GO:0051234 244 0.019
regulation of macromolecule metabolic process GO:0060255 317 0.019
hematopoietic stem cell differentiation GO:0060218 20 0.019
inositol lipid mediated signaling GO:0048017 2 0.019
ribose phosphate metabolic process GO:0019693 27 0.019
protein targeting to nucleus GO:0044744 3 0.019
detection of stimulus involved in sensory perception GO:0050906 21 0.019
heart contraction GO:0060047 71 0.019
heterocycle biosynthetic process GO:0018130 215 0.019
sensory perception of light stimulus GO:0050953 19 0.019
regulation of protein targeting GO:1903533 2 0.019
regulation of circadian rhythm GO:0042752 4 0.018
regulation of nucleotide metabolic process GO:0006140 17 0.018
striated muscle tissue development GO:0014706 110 0.018
actin filament based movement GO:0030048 1 0.018
maintenance of location GO:0051235 4 0.018
purine containing compound metabolic process GO:0072521 29 0.018
lipid storage GO:0019915 1 0.018
regulation of synapse assembly GO:0051963 3 0.018
regulation of developmental process GO:0050793 247 0.018
negative regulation of synapse assembly GO:0051964 2 0.018
cytoplasm organization GO:0007028 4 0.018
regulation of metal ion transport GO:0010959 4 0.018
unidimensional cell growth GO:0009826 5 0.018
sensory perception of chemical stimulus GO:0007606 3 0.017
protein import into nucleus GO:0006606 3 0.017
single organism nuclear import GO:1902593 3 0.017
regulation of hydrolase activity GO:0051336 28 0.017
determination of heart left right asymmetry GO:0061371 117 0.017
mitochondrion organization GO:0007005 4 0.017
regulation of neuronal synaptic plasticity GO:0048168 1 0.017
negative regulation of muscle tissue development GO:1901862 2 0.017
protein complex subunit organization GO:0071822 46 0.017
embryonic heart tube morphogenesis GO:0003143 108 0.016
cell matrix adhesion GO:0007160 4 0.016
developmental growth GO:0048589 166 0.016
embryonic heart tube development GO:0035050 133 0.016
convergent extension GO:0060026 118 0.016
central nervous system development GO:0007417 387 0.016
response to nutrient GO:0007584 3 0.016
oocyte anterior posterior axis specification GO:0007314 4 0.016
response to lipid GO:0033993 60 0.016
homeostasis of number of cells GO:0048872 62 0.016
regulation of cell matrix adhesion GO:0001952 1 0.016
actin cytoskeleton organization GO:0030036 63 0.016
phosphate containing compound metabolic process GO:0006796 108 0.016
embryonic organ morphogenesis GO:0048562 274 0.016
determination of bilateral symmetry GO:0009855 204 0.016
regulation of cardiac muscle tissue development GO:0055024 1 0.015
regulation of tube size GO:0035150 2 0.015
regulation of protein localization to nucleus GO:1900180 2 0.015
calcium ion import GO:0070509 4 0.015
nucleic acid templated transcription GO:0097659 181 0.015
regulation of ras gtpase activity GO:0032318 2 0.015
nucleobase containing small molecule metabolic process GO:0055086 32 0.015
response to organic substance GO:0010033 153 0.015
positive regulation of cell matrix adhesion GO:0001954 1 0.015
regulation of heart contraction GO:0008016 32 0.015
nucleotide metabolic process GO:0009117 28 0.015
cellular component movement GO:0006928 335 0.015
sensory perception GO:0007600 39 0.015
brain development GO:0007420 293 0.015
macromolecule biosynthetic process GO:0009059 227 0.015
cellular component disassembly GO:0022411 1 0.014
regulation of biosynthetic process GO:0009889 250 0.014
regulation of macromolecule biosynthetic process GO:0010556 225 0.014
regulation of molecular function GO:0065009 70 0.014
cellular response to oxygen levels GO:0071453 1 0.014
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.014
response to radiation GO:0009314 51 0.014
cell substrate adhesion GO:0031589 4 0.014
purine ribonucleotide metabolic process GO:0009150 27 0.014
response to stress GO:0006950 263 0.014
stem cell maintenance GO:0019827 4 0.014
compound eye development GO:0048749 2 0.014
regulation of signaling GO:0023051 235 0.014
epiboly GO:0090504 41 0.014
regulation of purine nucleotide metabolic process GO:1900542 17 0.014
single organism cellular localization GO:1902580 46 0.014
ear development GO:0043583 127 0.014
regulation of receptor activity GO:0010469 2 0.014
regulation of cell death GO:0010941 103 0.013
rna metabolic process GO:0016070 219 0.013
positive regulation of cell cycle GO:0045787 3 0.013
apical junction assembly GO:0043297 1 0.013
nucleobase containing compound biosynthetic process GO:0034654 205 0.013
rna localization GO:0006403 4 0.013
organelle organization GO:0006996 227 0.013
skeletal muscle tissue development GO:0007519 67 0.013
sensory perception of pain GO:0019233 1 0.013
regulation of anatomical structure morphogenesis GO:0022603 130 0.013
appendage development GO:0048736 80 0.013
neurotransmitter secretion GO:0007269 2 0.013
cellular response to radiation GO:0071478 4 0.013
morphogenesis of an epithelial fold GO:0060571 1 0.013
cellular response to hypoxia GO:0071456 1 0.013
macromolecular complex subunit organization GO:0043933 74 0.013
pancreas development GO:0031016 84 0.013
epithelial tube morphogenesis GO:0060562 148 0.013
regulation of blood vessel size GO:0050880 2 0.013
somatic muscle development GO:0007525 4 0.013
regulation of nucleic acid templated transcription GO:1903506 213 0.013
b cell activation GO:0042113 2 0.013
cognition GO:0050890 1 0.012
cellular macromolecule localization GO:0070727 21 0.012
response to acid chemical GO:0001101 17 0.012
protein complex localization GO:0031503 1 0.012
embryonic organ development GO:0048568 381 0.012
macromolecular complex disassembly GO:0032984 1 0.012
regulation of muscle contraction GO:0006937 3 0.012
exocytosis GO:0006887 1 0.012
response to topologically incorrect protein GO:0035966 2 0.012
regulation of cellular metabolic process GO:0031323 320 0.012
regulation of response to stimulus GO:0048583 269 0.012
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.012
regulation of cellular component organization GO:0051128 86 0.012
regulation of dna templated transcription elongation GO:0032784 3 0.012
gland development GO:0048732 143 0.012
actin polymerization or depolymerization GO:0008154 2 0.012
meiotic nuclear division GO:0007126 4 0.012
cellular biosynthetic process GO:0044249 286 0.012
epithelial cell morphogenesis GO:0003382 2 0.012
regulation of multicellular organismal development GO:2000026 223 0.012
single organism cell adhesion GO:0098602 29 0.012
calcium mediated signaling GO:0019722 2 0.012
regulation of protein depolymerization GO:1901879 1 0.012
camera type eye development GO:0043010 222 0.012
female sex differentiation GO:0046660 4 0.012
regulation of sodium ion transport GO:0002028 2 0.012
cytoskeleton organization GO:0007010 96 0.012
negative regulation of protein kinase activity GO:0006469 4 0.012
dna templated transcription elongation GO:0006354 3 0.012
establishment of synaptic vesicle localization GO:0097480 1 0.011
positive regulation of cell substrate adhesion GO:0010811 1 0.011
detection of light stimulus involved in visual perception GO:0050908 7 0.011
cortical actin cytoskeleton organization GO:0030866 1 0.011
single fertilization GO:0007338 3 0.011
regulation of epithelial cell proliferation GO:0050678 3 0.011
regulation of rho gtpase activity GO:0032319 1 0.011
protein targeting to membrane GO:0006612 1 0.011
positive regulation of ras gtpase activity GO:0032320 1 0.011
synaptic vesicle localization GO:0097479 1 0.011
meiotic cell cycle process GO:1903046 3 0.011
multicellular organism growth GO:0035264 4 0.011
purine nucleoside monophosphate catabolic process GO:0009128 4 0.011
positive regulation of epithelial cell proliferation GO:0050679 1 0.011
positive regulation of cell adhesion GO:0045785 1 0.011
cortical cytoskeleton organization GO:0030865 1 0.011
developmental programmed cell death GO:0010623 4 0.011
cell substrate junction assembly GO:0007044 2 0.011
negative regulation of muscle organ development GO:0048635 5 0.011
regulation of transporter activity GO:0032409 2 0.011
auditory receptor cell fate commitment GO:0009912 4 0.011
heterocycle catabolic process GO:0046700 15 0.011
astrocyte differentiation GO:0048708 1 0.011
cellular response to decreased oxygen levels GO:0036294 1 0.011
synaptic vesicle transport GO:0048489 1 0.011
response to corticosteroid GO:0031960 1 0.011
localization of cell GO:0051674 244 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.011
membrane fusion GO:0061025 2 0.011
protein complex disassembly GO:0043241 1 0.011
cell substrate adherens junction assembly GO:0007045 1 0.011
embryonic limb morphogenesis GO:0030326 2 0.011
positive regulation of muscle organ development GO:0048636 1 0.011
morphogenesis of an epithelial sheet GO:0002011 49 0.011
regulation of cell differentiation GO:0045595 142 0.011
rna biosynthetic process GO:0032774 181 0.011
endocardial cushion formation GO:0003272 2 0.011
proteasomal protein catabolic process GO:0010498 2 0.011
regulation of protein import into nucleus GO:0042306 2 0.010
regulation of multicellular organism growth GO:0040014 4 0.010
epidermal cell fate specification GO:0009957 4 0.010
negative regulation of intracellular transport GO:0032387 3 0.010
mesenchyme development GO:0060485 127 0.010
cellular response to chemical stimulus GO:0070887 157 0.010
water homeostasis GO:0030104 4 0.010
inner ear receptor cell fate commitment GO:0060120 4 0.010
regulation of cardiac muscle contraction GO:0055117 2 0.010
organelle assembly GO:0070925 110 0.010
regulation of catalytic activity GO:0050790 55 0.010
actin filament organization GO:0007015 15 0.010
regulation of systemic arterial blood pressure GO:0003073 1 0.010

s100z disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.015
nervous system disease DOID:863 0 0.011
disease of metabolism DOID:0014667 0 0.010