Danio rerio

0 known processes

psmc6

proteasome (prosome, macropain) 26S subunit, ATPase, 6

(Aliases: wu:fc85c10,wu:fb20g04,fb20g04,MGC101799)

psmc6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular protein catabolic process GO:0044257 4 0.924
embryo development ending in birth or egg hatching GO:0009792 271 0.881
Worm
larval development GO:0002164 2 0.858
Worm
modification dependent protein catabolic process GO:0019941 3 0.749
modification dependent macromolecule catabolic process GO:0043632 3 0.732
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.714
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.647
aging GO:0007568 2 0.634
Worm
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.621
single fertilization GO:0007338 3 0.591
ubiquitin dependent protein catabolic process GO:0006511 3 0.547
organelle fission GO:0048285 23 0.487
purine nucleoside monophosphate catabolic process GO:0009128 4 0.476
positive regulation of cellular component biogenesis GO:0044089 3 0.474
proteasomal protein catabolic process GO:0010498 2 0.455
ribonucleoside monophosphate catabolic process GO:0009158 4 0.430
locomotion GO:0040011 313 0.413
Worm
dna templated transcription initiation GO:0006352 1 0.408
sensory organ development GO:0007423 393 0.397
positive regulation of protein complex assembly GO:0031334 2 0.364
nucleic acid metabolic process GO:0090304 244 0.358
Fly
regulation of macromolecule metabolic process GO:0060255 317 0.351
Fly
rrna catabolic process GO:0016075 1 0.343
spindle assembly involved in mitosis GO:0090307 1 0.341
mitotic nuclear division GO:0007067 18 0.326
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.316
nucleoside monophosphate catabolic process GO:0009125 4 0.307
protein metabolic process GO:0019538 183 0.300
Fly
mitotic cell cycle process GO:1903047 48 0.296
cellular macromolecule metabolic process GO:0044260 391 0.270
Fly
fertilization GO:0009566 3 0.263
regulation of cellular metabolic process GO:0031323 320 0.247
Fly
regulation of protein complex assembly GO:0043254 3 0.246
gene expression GO:0010467 252 0.246
Fly
regulation of cellular component organization GO:0051128 86 0.243
reproduction GO:0000003 40 0.228
Worm
meiotic nuclear division GO:0007126 4 0.221
nitrogen compound metabolic process GO:0006807 319 0.217
Fly
rna metabolic process GO:0016070 219 0.204
Fly
atp catabolic process GO:0006200 4 0.203
regulation of rna biosynthetic process GO:2001141 213 0.194
Fly
sexual reproduction GO:0019953 36 0.189
response to stress GO:0006950 263 0.182
pole plasm assembly GO:0007315 4 0.181
organic substance biosynthetic process GO:1901576 289 0.178
Fly
pronuclear migration GO:0035046 1 0.177
cellular component biogenesis GO:0044085 178 0.156
cellular protein metabolic process GO:0044267 129 0.150
cell motility GO:0048870 244 0.146
rna catabolic process GO:0006401 7 0.145
establishment of localization GO:0051234 244 0.140
single organism organelle organization GO:1902589 199 0.139
chromosome segregation GO:0007059 12 0.138
positive regulation of cellular process GO:0048522 201 0.137
Fly
regulation of gene expression GO:0010468 265 0.135
Fly
mitotic cell cycle GO:0000278 64 0.129
meiotic cell cycle process GO:1903046 3 0.129
cellular catabolic process GO:0044248 27 0.128
protein complex subunit organization GO:0071822 46 0.125
regulation of rna metabolic process GO:0051252 224 0.121
Fly
oocyte anterior posterior axis specification GO:0007314 4 0.119
regulation of meiotic cell cycle GO:0051445 1 0.119
regulation of primary metabolic process GO:0080090 311 0.118
Fly
heterocycle metabolic process GO:0046483 290 0.118
Fly
regulation of metabolic process GO:0019222 359 0.117
Fly
spindle assembly GO:0051225 2 0.116
cellular component assembly GO:0022607 170 0.115
gamete generation GO:0007276 33 0.112
organelle organization GO:0006996 227 0.111
macromolecule catabolic process GO:0009057 15 0.110
macromolecular complex subunit organization GO:0043933 74 0.105
maintenance of location GO:0051235 4 0.103
microtubule based process GO:0007017 60 0.101
mitotic sister chromatid segregation GO:0000070 6 0.099
negative regulation of biological process GO:0048519 304 0.097
positive regulation of biological process GO:0048518 253 0.097
Fly
regulation of nitrogen compound metabolic process GO:0051171 251 0.096
Fly
microtubule cytoskeleton organization GO:0000226 33 0.094
regulation of cellular biosynthetic process GO:0031326 245 0.093
Fly
cellular response to dna damage stimulus GO:0006974 24 0.091
transport GO:0006810 220 0.091
multicellular organismal reproductive process GO:0048609 35 0.089
multicellular organism growth GO:0035264 4 0.089
positive regulation of cellular metabolic process GO:0031325 94 0.086
Fly
regulation of protein catabolic process GO:0042176 1 0.084
regulation of transcription dna templated GO:0006355 213 0.083
Fly
regulation of developmental process GO:0050793 247 0.082
reproductive process GO:0022414 40 0.081
regulation of mitotic cell cycle GO:0007346 25 0.081
alternative mrna splicing via spliceosome GO:0000380 1 0.079
regulation of macromolecule biosynthetic process GO:0010556 225 0.078
Fly
regulation of mrna splicing via spliceosome GO:0048024 3 0.076
regulation of multicellular organismal process GO:0051239 277 0.076
nucleic acid templated transcription GO:0097659 181 0.076
Fly
camera type eye development GO:0043010 222 0.075
positive regulation of metabolic process GO:0009893 108 0.074
Fly
lipid storage GO:0019915 1 0.074
cellular biosynthetic process GO:0044249 286 0.074
Fly
positive regulation of macromolecule metabolic process GO:0010604 93 0.074
Fly
cell migration GO:0016477 237 0.074
response to chemical GO:0042221 320 0.073
regulation of multicellular organism growth GO:0040014 4 0.072
cellular aromatic compound metabolic process GO:0006725 295 0.072
Fly
cellular response to stress GO:0033554 62 0.072
negative regulation of cellular process GO:0048523 283 0.072
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.072
protein catabolic process GO:0030163 7 0.071
female sex differentiation GO:0046660 4 0.071
catabolic process GO:0009056 32 0.070
single organism metabolic process GO:0044710 217 0.070
organic substance catabolic process GO:1901575 28 0.070
multicellular organism reproduction GO:0032504 35 0.069
regulation of biological quality GO:0065008 263 0.067
meiotic chromosome segregation GO:0045132 3 0.067
organic cyclic compound biosynthetic process GO:1901362 223 0.066
Fly
single organism localization GO:1902578 225 0.066
proteolysis GO:0006508 38 0.065
Fly
phosphorus metabolic process GO:0006793 109 0.065
cellular macromolecule biosynthetic process GO:0034645 224 0.065
Fly
autophagy GO:0006914 4 0.063
chromosome organization GO:0051276 31 0.063
nuclear division GO:0000280 23 0.063
organonitrogen compound metabolic process GO:1901564 74 0.062
transcription dna templated GO:0006351 181 0.062
Fly
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.061
Fly
heart development GO:0007507 313 0.059
protein secretion GO:0009306 1 0.059
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.058
organic cyclic compound metabolic process GO:1901360 301 0.057
Fly
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.056
Fly
cellular nitrogen compound metabolic process GO:0034641 290 0.054
Fly
embryonic organ development GO:0048568 381 0.054
phosphate containing compound metabolic process GO:0006796 108 0.052
cellular macromolecule catabolic process GO:0044265 12 0.052
nucleobase containing compound biosynthetic process GO:0034654 205 0.051
Fly
negative regulation of cytoplasmic transport GO:1903650 2 0.051
cell cycle process GO:0022402 53 0.051
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.050
response to abiotic stimulus GO:0009628 122 0.050
regionalization GO:0003002 274 0.049
nuclear migration GO:0007097 3 0.049
cellular nitrogen compound biosynthetic process GO:0044271 218 0.049
Fly
positive regulation of cellular catabolic process GO:0031331 3 0.049
small molecule metabolic process GO:0044281 77 0.047
cell division GO:0051301 20 0.047
transcription from rna polymerase ii promoter GO:0006366 80 0.047
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.047
single organism transport GO:0044765 206 0.045
heterocycle biosynthetic process GO:0018130 215 0.045
Fly
regulation of chromosome segregation GO:0051983 1 0.043
protein modification by small protein removal GO:0070646 1 0.043
positive regulation of catabolic process GO:0009896 4 0.043
purine containing compound metabolic process GO:0072521 29 0.042
cytoskeleton organization GO:0007010 96 0.042
multi organism process GO:0051704 134 0.042
purine ribonucleotide metabolic process GO:0009150 27 0.042
double strand break repair via homologous recombination GO:0000724 1 0.042
female gamete generation GO:0007292 14 0.041
cellular protein modification process GO:0006464 100 0.041
development of primary female sexual characteristics GO:0046545 4 0.041
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 1 0.040
eye development GO:0001654 277 0.040
regulation of cell differentiation GO:0045595 142 0.040
chordate embryonic development GO:0043009 271 0.039
protein complex assembly GO:0006461 30 0.038
centrosome organization GO:0051297 1 0.037
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.037
Fly
regulation of biosynthetic process GO:0009889 250 0.037
Fly
response to temperature stimulus GO:0009266 15 0.037
cell cycle GO:0007049 93 0.036
single organism reproductive process GO:0044702 40 0.035
embryonic pattern specification GO:0009880 44 0.035
developmental growth GO:0048589 166 0.035
ncrna catabolic process GO:0034661 1 0.035
regulation of response to stimulus GO:0048583 269 0.035
protein complex biogenesis GO:0070271 30 0.034
dna biosynthetic process GO:0071897 3 0.034
regulation of immune system process GO:0002682 34 0.034
post embryonic development GO:0009791 7 0.034
Worm
double strand break repair GO:0006302 3 0.033
neuron development GO:0048666 262 0.033
purine ribonucleoside monophosphate metabolic process GO:0009167 5 0.033
programmed cell death GO:0012501 119 0.033
positive regulation of gene expression GO:0010628 71 0.032
Fly
regulation of cell cycle process GO:0010564 20 0.032
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.032
cellular localization GO:0051641 97 0.032
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.032
Fly
regulation of nucleic acid templated transcription GO:1903506 213 0.032
Fly
rna biosynthetic process GO:0032774 181 0.031
Fly
carbohydrate derivative metabolic process GO:1901135 61 0.031
cellular response to chemical stimulus GO:0070887 157 0.031
dorsal ventral pattern formation GO:0009953 125 0.031
purine nucleotide metabolic process GO:0006163 27 0.030
neuroblast proliferation GO:0007405 2 0.030
regulation of synapse organization GO:0050807 3 0.030
oocyte development GO:0048599 14 0.030
germ cell development GO:0007281 22 0.030
cellular component movement GO:0006928 335 0.030
cell morphogenesis GO:0000902 289 0.030
cell projection organization GO:0030030 284 0.029
rna localization GO:0006403 4 0.029
regulation of dna templated transcription elongation GO:0032784 3 0.029
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.029
response to external stimulus GO:0009605 264 0.029
regulation of mrna processing GO:0050684 3 0.028
regulation of protein metabolic process GO:0051246 56 0.028
regulation of cellular protein metabolic process GO:0032268 52 0.028
sister chromatid segregation GO:0000819 6 0.028
segmentation GO:0035282 97 0.028
regulation of programmed cell death GO:0043067 101 0.028
negative regulation of defense response GO:0031348 2 0.027
cytoplasm organization GO:0007028 4 0.027
cellular macromolecular complex assembly GO:0034622 24 0.027
biosynthetic process GO:0009058 294 0.026
Fly
anterior posterior pattern specification GO:0009952 152 0.026
retina development in camera type eye GO:0060041 146 0.026
regulation of molecular function GO:0065009 70 0.026
positive regulation of transcription dna templated GO:0045893 57 0.026
Fly
response to endogenous stimulus GO:0009719 83 0.026
positive regulation of cell cycle GO:0045787 3 0.025
regulation of sequence specific dna binding transcription factor activity GO:0051090 9 0.025
female gonad development GO:0008585 4 0.025
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.025
negative regulation of mitosis GO:0045839 3 0.025
ribonucleotide metabolic process GO:0009259 27 0.025
regulation of cell cycle GO:0051726 52 0.025
regulation of cellular component biogenesis GO:0044087 12 0.025
regulation of synapse assembly GO:0051963 3 0.025
localization of cell GO:0051674 244 0.025
maternal determination of anterior posterior axis embryo GO:0008358 4 0.024
angiogenesis GO:0001525 158 0.024
macromolecular complex assembly GO:0065003 35 0.024
cell proliferation GO:0008283 80 0.024
regulation of protein ubiquitination GO:0031396 3 0.024
negative regulation of neural precursor cell proliferation GO:2000178 1 0.024
macromolecule modification GO:0043412 111 0.024
ncrna metabolic process GO:0034660 12 0.023
positive regulation of dna metabolic process GO:0051054 1 0.023
regulation of cell communication GO:0010646 232 0.023
protein polymerization GO:0051258 4 0.023
regulation of nuclear division GO:0051783 9 0.023
establishment of localization in cell GO:0051649 77 0.023
growth GO:0040007 174 0.022
mitotic g2 dna damage checkpoint GO:0007095 3 0.022
meiosis i GO:0007127 1 0.022
regulation of neural precursor cell proliferation GO:2000177 3 0.022
protein polyubiquitination GO:0000209 4 0.022
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.022
dna templated transcription elongation GO:0006354 3 0.022
regulation of mitosis GO:0007088 9 0.022
regulation of cellular protein catabolic process GO:1903362 1 0.022
organophosphate metabolic process GO:0019637 37 0.022
cellular protein complex assembly GO:0043623 19 0.021
developmental maturation GO:0021700 34 0.021
ovarian follicle development GO:0001541 2 0.021
organelle assembly GO:0070925 110 0.021
internal peptidyl lysine acetylation GO:0018393 2 0.021
oogenesis GO:0048477 14 0.021
regulation of organelle organization GO:0033043 29 0.020
vasculature development GO:0001944 278 0.020
nucleoside phosphate metabolic process GO:0006753 28 0.020
death GO:0016265 121 0.020
cellular response to organic substance GO:0071310 105 0.020
nucleobase containing compound metabolic process GO:0006139 274 0.020
Fly
embryonic organ morphogenesis GO:0048562 274 0.019
chemotaxis GO:0006935 104 0.019
cytokinesis GO:0000910 3 0.019
regulation of proteolysis GO:0030162 24 0.019
positive regulation of biosynthetic process GO:0009891 68 0.019
Fly
regulation of oocyte development GO:0060281 3 0.019
negative regulation of protein transport GO:0051224 3 0.019
heterocycle catabolic process GO:0046700 15 0.019
blood vessel morphogenesis GO:0048514 216 0.019
negative regulation of macromolecule metabolic process GO:0010605 76 0.019
embryonic skeletal system morphogenesis GO:0048704 93 0.019
microtubule organizing center organization GO:0031023 1 0.019
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.019
Fly
tube morphogenesis GO:0035239 349 0.018
negative regulation of metabolic process GO:0009892 86 0.018
phagocytosis GO:0006909 3 0.018
ovulation cycle GO:0042698 2 0.018
mitotic metaphase plate congression GO:0007080 1 0.018
cell projection morphogenesis GO:0048858 244 0.018
cytoskeleton dependent cytokinesis GO:0061640 3 0.018
regulation of binding GO:0051098 3 0.018
positive regulation of rna metabolic process GO:0051254 59 0.018
Fly
positive regulation of dna templated transcription elongation GO:0032786 1 0.018
axis specification GO:0009798 43 0.017
macromolecule biosynthetic process GO:0009059 227 0.017
Fly
positive regulation of developmental process GO:0051094 50 0.017
cell cycle phase transition GO:0044770 9 0.017
hematopoietic or lymphoid organ development GO:0048534 191 0.017
nuclear transport GO:0051169 4 0.017
developmental programmed cell death GO:0010623 4 0.017
regulation of cell division GO:0051302 12 0.017
macromolecule localization GO:0033036 54 0.017
cellular component disassembly GO:0022411 1 0.017
regulation of locomotion GO:0040012 55 0.017
hatching GO:0035188 4 0.016
regulation of endopeptidase activity GO:0052548 23 0.016
developmental process involved in reproduction GO:0003006 27 0.016
protein modification by small protein conjugation or removal GO:0070647 14 0.016
regulation of gene expression epigenetic GO:0040029 11 0.016
regulation of cytoplasmic transport GO:1903649 4 0.016
negative regulation of synapse assembly GO:0051964 2 0.016
aromatic compound biosynthetic process GO:0019438 217 0.016
Fly
apoptotic process involved in development GO:1902742 2 0.016
cellular response to external stimulus GO:0071496 2 0.016
protein modification process GO:0036211 100 0.016
multi organism reproductive process GO:0044703 36 0.016
embryonic cranial skeleton morphogenesis GO:0048701 90 0.016
regulation of establishment of protein localization GO:0070201 4 0.015
positive regulation of cellular biosynthetic process GO:0031328 68 0.015
Fly
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 7 0.015
apoptotic process involved in morphogenesis GO:0060561 2 0.015
neuron differentiation GO:0030182 353 0.015
stem cell proliferation GO:0072089 4 0.015
chromatin organization GO:0006325 22 0.015
cell cycle g2 m phase transition GO:0044839 4 0.015
generation of neurons GO:0048699 385 0.014
negative regulation of gene expression GO:0010629 65 0.014
response to organic substance GO:0010033 153 0.014
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.014
regulation of multicellular organismal development GO:2000026 223 0.014
negative regulation of molecular function GO:0044092 23 0.014
negative regulation of signal transduction GO:0009968 94 0.014
embryonic skeletal system development GO:0048706 97 0.014
regulation of anatomical structure morphogenesis GO:0022603 130 0.014
nucleoside monophosphate metabolic process GO:0009123 6 0.014
cell surface receptor signaling pathway GO:0007166 325 0.014
aromatic compound catabolic process GO:0019439 15 0.014
regulation of developmental growth GO:0048638 38 0.014
maturation of ssu rrna GO:0030490 1 0.014
immune system process GO:0002376 241 0.014
regulation of cell activation GO:0050865 1 0.014
cell part morphogenesis GO:0032990 246 0.014
neuron projection morphogenesis GO:0048812 161 0.013
taxis GO:0042330 109 0.013
regulation of signal transduction GO:0009966 225 0.013
regulation of inflammatory response GO:0050727 2 0.013
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.013
atp metabolic process GO:0046034 5 0.013
organism emergence from protective structure GO:0071684 4 0.013
regulation of apoptotic process GO:0042981 98 0.013
translational initiation GO:0006413 3 0.013
negative regulation of nuclear division GO:0051784 3 0.013
positive regulation of nucleic acid templated transcription GO:1903508 57 0.013
Fly
nucleocytoplasmic transport GO:0006913 4 0.013
cell cycle g1 s phase transition GO:0044843 1 0.013
regulation of stem cell proliferation GO:0072091 2 0.013
response to heat GO:0009408 6 0.013
protein localization GO:0008104 40 0.013
negative regulation of cellular metabolic process GO:0031324 77 0.013
meiosis ii GO:0007135 1 0.013
dna repair GO:0006281 6 0.012
neuron projection development GO:0031175 180 0.012
macromolecular complex disassembly GO:0032984 1 0.012
regeneration GO:0031099 91 0.012
cellular amine metabolic process GO:0044106 2 0.012
negative regulation of immune response GO:0050777 2 0.012
regulation of signaling GO:0023051 235 0.012
organic acid metabolic process GO:0006082 31 0.012
posttranscriptional regulation of gene expression GO:0010608 14 0.012
regulation of erk1 and erk2 cascade GO:0070372 4 0.012
gland development GO:0048732 143 0.012
ribosomal small subunit biogenesis GO:0042274 2 0.012
brain development GO:0007420 293 0.012
recombinational repair GO:0000725 1 0.012
protein localization to nucleus GO:0034504 3 0.012
purine nucleoside monophosphate metabolic process GO:0009126 5 0.012
dna metabolic process GO:0006259 27 0.012
nucleobase containing small molecule metabolic process GO:0055086 32 0.011
intestinal absorption GO:0050892 2 0.011
anterior posterior axis specification GO:0009948 20 0.011
regulation of nucleoside metabolic process GO:0009118 2 0.011
ameboidal type cell migration GO:0001667 143 0.011
regulation of response to external stimulus GO:0032101 31 0.011
positive regulation of response to stimulus GO:0048584 80 0.011
regulation of response to oxidative stress GO:1902882 2 0.011
positive regulation of multicellular organismal process GO:0051240 52 0.011
positive regulation of chromosome organization GO:2001252 1 0.011
adult behavior GO:0030534 2 0.011
mitochondrion organization GO:0007005 4 0.011
rrna metabolic process GO:0016072 8 0.011
spermatogenesis GO:0007283 7 0.011
cellular response to nutrient levels GO:0031669 2 0.011
guanosine containing compound catabolic process GO:1901069 2 0.011
small gtpase mediated signal transduction GO:0007264 8 0.011
negative regulation of signaling GO:0023057 96 0.011
protein complex localization GO:0031503 1 0.011
cellular response to starvation GO:0009267 1 0.010
ribose phosphate metabolic process GO:0019693 27 0.010
meiotic spindle organization GO:0000212 1 0.010
single organism biosynthetic process GO:0044711 71 0.010
response to wounding GO:0009611 116 0.010
cell fate commitment GO:0045165 99 0.010
protein dephosphorylation GO:0006470 3 0.010
mitotic dna damage checkpoint GO:0044773 4 0.010
cellular macromolecule localization GO:0070727 21 0.010
nucleotide metabolic process GO:0009117 28 0.010
positive regulation of rna splicing GO:0033120 1 0.010
homeostatic process GO:0042592 142 0.010
gtp metabolic process GO:0046039 4 0.010

psmc6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.026
nervous system disease DOID:863 0 0.012
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011