Danio rerio

15 known processes

LOC560057

prostaglandin E receptor 4, subtype EP4-like

LOC560057 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.054
response to external stimulus GO:0009605 264 0.052
positive regulation of transport GO:0051050 2 0.050
maintenance of location GO:0051235 4 0.043
adult behavior GO:0030534 2 0.041
single organism transport GO:0044765 206 0.040
signal transduction GO:0007165 455 0.038
response to chemical GO:0042221 320 0.037
establishment of localization GO:0051234 244 0.037
aging GO:0007568 2 0.035
specification of symmetry GO:0009799 204 0.035
determination of bilateral symmetry GO:0009855 204 0.035
neuron differentiation GO:0030182 353 0.034
regulation of inflammatory response GO:0050727 2 0.034
hormone transport GO:0009914 2 0.034
embryonic organ development GO:0048568 381 0.033
positive regulation of catabolic process GO:0009896 4 0.033
regulation of metal ion transport GO:0010959 4 0.033
regulation of establishment of protein localization GO:0070201 4 0.033
transport GO:0006810 220 0.032
morphogenesis of an epithelium GO:0002009 333 0.032
cellular macromolecule metabolic process GO:0044260 391 0.032
regulation of biological quality GO:0065008 263 0.032
multicellular organism growth GO:0035264 4 0.032
glucose homeostasis GO:0042593 1 0.032
hormone secretion GO:0046879 2 0.031
organonitrogen compound metabolic process GO:1901564 74 0.031
positive regulation of cellular catabolic process GO:0031331 3 0.031
lipid storage GO:0019915 1 0.030
regulation of cytokine production GO:0001817 3 0.030
regulation of protein transport GO:0051223 3 0.030
cellular component morphogenesis GO:0032989 336 0.030
single organism localization GO:1902578 225 0.030
sensory organ development GO:0007423 393 0.029
cellular nitrogen compound biosynthetic process GO:0044271 218 0.029
regionalization GO:0003002 274 0.029
tube morphogenesis GO:0035239 349 0.029
heterocycle metabolic process GO:0046483 290 0.028
small molecule metabolic process GO:0044281 77 0.028
monovalent inorganic cation transport GO:0015672 42 0.028
phagocytosis GO:0006909 3 0.028
cellular response to external stimulus GO:0071496 2 0.028
generation of neurons GO:0048699 385 0.028
response to stress GO:0006950 263 0.028
cellular nitrogen compound metabolic process GO:0034641 290 0.028
central nervous system development GO:0007417 387 0.028
cell surface receptor signaling pathway GO:0007166 325 0.027
regulation of primary metabolic process GO:0080090 311 0.027
single organism metabolic process GO:0044710 217 0.027
negative regulation of protein phosphorylation GO:0001933 4 0.027
synaptic growth at neuromuscular junction GO:0051124 2 0.027
eye development GO:0001654 277 0.026
transmembrane transport GO:0055085 120 0.026
organic substance biosynthetic process GO:1901576 289 0.026
positive regulation of cellular component biogenesis GO:0044089 3 0.026
regulation of circadian rhythm GO:0042752 4 0.026
regulation of macromolecule metabolic process GO:0060255 317 0.026
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.026
dicarboxylic acid transport GO:0006835 1 0.025
cell part morphogenesis GO:0032990 246 0.025
cellular protein catabolic process GO:0044257 4 0.025
cellular response to extracellular stimulus GO:0031668 2 0.025
regulation of hormone secretion GO:0046883 2 0.025
response to carbohydrate GO:0009743 3 0.025
regulation of response to stimulus GO:0048583 269 0.025
response to hexose GO:0009746 3 0.025
nucleobase containing compound metabolic process GO:0006139 274 0.024
cell projection morphogenesis GO:0048858 244 0.024
guanosine containing compound metabolic process GO:1901068 4 0.024
nitrogen compound metabolic process GO:0006807 319 0.024
ion transmembrane transport GO:0034220 91 0.024
cellular biosynthetic process GO:0044249 286 0.024
regulation of multicellular organism growth GO:0040014 4 0.024
neurotransmitter transport GO:0006836 2 0.024
response to monosaccharide GO:0034284 3 0.024
amine metabolic process GO:0009308 2 0.024
carbohydrate homeostasis GO:0033500 1 0.024
gtp metabolic process GO:0046039 4 0.024
regulation of cellular amino acid metabolic process GO:0006521 0 0.024
regulation of cell activation GO:0050865 1 0.023
regulation of multicellular organismal process GO:0051239 277 0.023
ion transport GO:0006811 114 0.023
ubiquitin dependent protein catabolic process GO:0006511 3 0.023
cell morphogenesis GO:0000902 289 0.023
regulation of cellular metabolic process GO:0031323 320 0.023
determination of left right symmetry GO:0007368 179 0.023
neuron development GO:0048666 262 0.023
compound eye development GO:0048749 2 0.023
cell morphogenesis involved in differentiation GO:0000904 195 0.023
regulation of reproductive process GO:2000241 4 0.023
peptide transport GO:0015833 1 0.022
head development GO:0060322 303 0.022
response to glucose GO:0009749 3 0.022
regulation of synapse organization GO:0050807 3 0.022
locomotion GO:0040011 313 0.022
regulation of cellular amine metabolic process GO:0033238 0 0.022
positive regulation of biological process GO:0048518 253 0.022
response to drug GO:0042493 3 0.022
gtp catabolic process GO:0006184 2 0.022
guanosine containing compound catabolic process GO:1901069 2 0.022
protein localization to nucleus GO:0034504 3 0.022
organic cyclic compound metabolic process GO:1901360 301 0.022
leukocyte proliferation GO:0070661 1 0.021
regulation of metabolic process GO:0019222 359 0.021
modification dependent macromolecule catabolic process GO:0043632 3 0.021
protein localization to plasma membrane GO:0072659 1 0.021
cellular aromatic compound metabolic process GO:0006725 295 0.021
cognition GO:0050890 1 0.021
g protein coupled receptor signaling pathway GO:0007186 74 0.021
biosynthetic process GO:0009058 294 0.021
system process GO:0003008 185 0.021
embryonic organ morphogenesis GO:0048562 274 0.021
chemosensory behavior GO:0007635 1 0.021
gene expression GO:0010467 252 0.021
nucleobase containing compound biosynthetic process GO:0034654 205 0.021
cellular response to starvation GO:0009267 1 0.021
modification dependent protein catabolic process GO:0019941 3 0.020
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.020
heart development GO:0007507 313 0.020
neurotransmitter secretion GO:0007269 2 0.020
cellular response to nutrient levels GO:0031669 2 0.020
cellular amide metabolic process GO:0043603 4 0.020
regulation of blood vessel size GO:0050880 2 0.020
regulation of synapse assembly GO:0051963 3 0.020
axon development GO:0061564 166 0.020
regulation of tube size GO:0035150 2 0.020
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.020
regulation of nitrogen compound metabolic process GO:0051171 251 0.020
negative regulation of secretion by cell GO:1903531 2 0.020
brain development GO:0007420 293 0.019
cellular component movement GO:0006928 335 0.019
digestive system development GO:0055123 289 0.019
regulation of signal transduction GO:0009966 225 0.019
cellular ketone metabolic process GO:0042180 11 0.019
aromatic compound biosynthetic process GO:0019438 217 0.019
negative regulation of secretion GO:0051048 2 0.019
chordate embryonic development GO:0043009 271 0.019
autophagy GO:0006914 4 0.019
regulation of protein complex assembly GO:0043254 3 0.019
inorganic cation transmembrane transport GO:0098662 50 0.019
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.019
negative regulation of cellular process GO:0048523 283 0.019
energy reserve metabolic process GO:0006112 2 0.019
amino acid transport GO:0006865 2 0.019
stem cell maintenance GO:0019827 4 0.019
positive regulation of secretion GO:0051047 1 0.019
neuron projection morphogenesis GO:0048812 161 0.019
sodium ion transmembrane transport GO:0035725 21 0.019
negative regulation of biological process GO:0048519 304 0.019
heterocycle biosynthetic process GO:0018130 215 0.019
negative regulation of protein kinase activity GO:0006469 4 0.019
mitochondrion organization GO:0007005 4 0.019
regulation of blood pressure GO:0008217 1 0.019
sequestering of calcium ion GO:0051208 3 0.018
cation transmembrane transport GO:0098655 65 0.018
nucleic acid templated transcription GO:0097659 181 0.018
cellular amine metabolic process GO:0044106 2 0.018
organic cyclic compound biosynthetic process GO:1901362 223 0.018
rna metabolic process GO:0016070 219 0.018
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.018
positive regulation of immune effector process GO:0002699 3 0.018
cytokinesis GO:0000910 3 0.018
regulation of cellular ketone metabolic process GO:0010565 7 0.018
taxis GO:0042330 109 0.018
nucleocytoplasmic transport GO:0006913 4 0.018
neuron projection development GO:0031175 180 0.018
macromolecule biosynthetic process GO:0009059 227 0.018
endocrine process GO:0050886 2 0.018
axonogenesis GO:0007409 152 0.018
nuclear import GO:0051170 3 0.018
regulation of dendrite development GO:0050773 3 0.018
establishment of protein localization to organelle GO:0072594 4 0.018
sequestering of metal ion GO:0051238 3 0.018
female sex differentiation GO:0046660 4 0.018
oxoacid metabolic process GO:0043436 31 0.018
regulation of cell communication GO:0010646 232 0.017
regulation of gene expression GO:0010468 265 0.017
cellular macromolecule biosynthetic process GO:0034645 224 0.017
protein secretion GO:0009306 1 0.017
regulation of cellular biosynthetic process GO:0031326 245 0.017
inositol lipid mediated signaling GO:0048017 2 0.017
immune system process GO:0002376 241 0.017
protein metabolic process GO:0019538 183 0.017
protein import GO:0017038 3 0.017
meiotic cell cycle process GO:1903046 3 0.017
negative regulation of kinase activity GO:0033673 4 0.017
response to biotic stimulus GO:0009607 97 0.017
response to wounding GO:0009611 116 0.017
protein targeting to nucleus GO:0044744 3 0.017
homeostatic process GO:0042592 142 0.017
cell projection organization GO:0030030 284 0.017
regulation of neurotransmitter secretion GO:0046928 1 0.017
organic acid metabolic process GO:0006082 31 0.017
dorsal ventral pattern formation GO:0009953 125 0.017
lipid catabolic process GO:0016042 4 0.017
neuron neuron synaptic transmission GO:0007270 1 0.017
mononuclear cell proliferation GO:0032943 1 0.017
chemotaxis GO:0006935 104 0.017
epithelial tube morphogenesis GO:0060562 148 0.016
regulation of signaling GO:0023051 235 0.016
camera type eye development GO:0043010 222 0.016
regulation of multicellular organismal development GO:2000026 223 0.016
transcription dna templated GO:0006351 181 0.016
response to organic substance GO:0010033 153 0.016
regulation of autophagy GO:0010506 3 0.016
regulation of calcium ion transport GO:0051924 2 0.016
stem cell proliferation GO:0072089 4 0.016
protein import into nucleus GO:0006606 3 0.016
positive regulation of cell activation GO:0050867 1 0.016
cation transport GO:0006812 81 0.016
regulation of cell shape GO:0008360 1 0.016
positive regulation of inflammatory response GO:0050729 1 0.016
anterior posterior pattern specification GO:0009952 152 0.016
positive regulation of cell cycle GO:0045787 3 0.016
regulation of response to nutrient levels GO:0032107 1 0.016
positive regulation of cellular process GO:0048522 201 0.016
cellular response to chemical stimulus GO:0070887 157 0.016
digestive tract morphogenesis GO:0048546 231 0.016
regulation of endocrine process GO:0044060 2 0.016
positive regulation of secretion by cell GO:1903532 1 0.016
carboxylic acid metabolic process GO:0019752 22 0.016
blood vessel development GO:0001568 246 0.015
regulation of cytoplasmic transport GO:1903649 4 0.015
single organism nuclear import GO:1902593 3 0.015
sensory perception of chemical stimulus GO:0007606 3 0.015
protein polymerization GO:0051258 4 0.015
vasculature development GO:0001944 278 0.015
eye morphogenesis GO:0048592 144 0.015
cytoskeleton dependent cytokinesis GO:0061640 3 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.015
developmental growth GO:0048589 166 0.015
regulation of developmental process GO:0050793 247 0.015
establishment of protein localization to plasma membrane GO:0090002 1 0.015
cellular amino acid metabolic process GO:0006520 7 0.015
positive regulation of cytokine production GO:0001819 2 0.015
cell killing GO:0001906 2 0.015
regulation of epithelial cell proliferation GO:0050678 3 0.015
sensory organ morphogenesis GO:0090596 200 0.015
cellular component disassembly GO:0022411 1 0.015
olfactory lobe development GO:0021988 4 0.015
regulation of purine nucleotide catabolic process GO:0033121 2 0.015
inorganic ion transmembrane transport GO:0098660 57 0.015
positive regulation of dna metabolic process GO:0051054 1 0.015
positive regulation of blood circulation GO:1903524 2 0.015
proteasomal protein catabolic process GO:0010498 2 0.015
actin filament based movement GO:0030048 1 0.015
regulation of nucleoside metabolic process GO:0009118 2 0.015
negative regulation of catabolic process GO:0009895 3 0.015
regulation of response to extracellular stimulus GO:0032104 1 0.014
protein acetylation GO:0006473 2 0.014
cell migration GO:0016477 237 0.014
smooth muscle contraction GO:0006939 2 0.014
regulation of neurotransmitter transport GO:0051588 1 0.014
exocytosis GO:0006887 1 0.014
regulation of protein catabolic process GO:0042176 1 0.014
metal ion transport GO:0030001 58 0.014
intracellular mrna localization GO:0008298 1 0.014
response to nutrient GO:0007584 3 0.014
nuclear transport GO:0051169 4 0.014
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.014
development of primary female sexual characteristics GO:0046545 4 0.014
cellular carbohydrate metabolic process GO:0044262 4 0.014
small molecule catabolic process GO:0044282 3 0.014
peptidyl lysine acetylation GO:0018394 2 0.014
cellular response to lipopolysaccharide GO:0071222 3 0.014
embryo development ending in birth or egg hatching GO:0009792 271 0.014
multicellular organismal response to stress GO:0033555 2 0.014
calcium ion transport into cytosol GO:0060402 3 0.014
rna biosynthetic process GO:0032774 181 0.014
regulation of ion transmembrane transporter activity GO:0032412 2 0.014
response to vitamin GO:0033273 3 0.014
nucleic acid metabolic process GO:0090304 244 0.014
phosphatidylinositol mediated signaling GO:0048015 2 0.014
regulation of binding GO:0051098 3 0.014
macromolecular complex disassembly GO:0032984 1 0.014
positive regulation of protein complex assembly GO:0031334 2 0.014
positive regulation of map kinase activity GO:0043406 3 0.014
heart morphogenesis GO:0003007 156 0.014
fluid transport GO:0042044 17 0.014
cellular response to molecule of bacterial origin GO:0071219 3 0.013
somatic muscle development GO:0007525 4 0.013
protein acylation GO:0043543 3 0.013
transcription from rna polymerase ii promoter GO:0006366 80 0.013
regulation of protein ubiquitination GO:0031396 3 0.013
response to abiotic stimulus GO:0009628 122 0.013
circulatory system process GO:0003013 87 0.013
cellular response to biotic stimulus GO:0071216 3 0.013
positive regulation of cellular amine metabolic process GO:0033240 0 0.013
b cell activation GO:0042113 2 0.013
regulation of muscle contraction GO:0006937 3 0.013
regulation of nucleic acid templated transcription GO:1903506 213 0.013
embryonic heart tube development GO:0035050 133 0.013
ribonucleoside monophosphate catabolic process GO:0009158 4 0.013
positive regulation of cell killing GO:0031343 2 0.013
cell death GO:0008219 121 0.013
somite development GO:0061053 96 0.013
cellular component biogenesis GO:0044085 178 0.013
leukocyte mediated cytotoxicity GO:0001909 1 0.013
internal protein amino acid acetylation GO:0006475 2 0.013
positive regulation of cytoskeleton organization GO:0051495 3 0.013
lymphocyte proliferation GO:0046651 1 0.013
blood circulation GO:0008015 87 0.013
lipid homeostasis GO:0055088 3 0.013
sodium ion transport GO:0006814 24 0.013
regulation of biosynthetic process GO:0009889 250 0.013
negative regulation of sequestering of calcium ion GO:0051283 4 0.013
heart looping GO:0001947 94 0.013
rna localization GO:0006403 4 0.013
protein homooligomerization GO:0051260 3 0.013
negative regulation of defense response GO:0031348 2 0.013
regulation of sequestering of calcium ion GO:0051282 4 0.013
production of molecular mediator of immune response GO:0002440 2 0.013
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.013
regulation of nucleotide catabolic process GO:0030811 2 0.013
fertilization GO:0009566 3 0.013
atp catabolic process GO:0006200 4 0.013
regulation of synaptic plasticity GO:0048167 1 0.013
positive regulation of reproductive process GO:2000243 2 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.013
response to other organism GO:0051707 97 0.013
blood vessel morphogenesis GO:0048514 216 0.012
regulation of reactive oxygen species metabolic process GO:2000377 2 0.012
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.012
internal peptidyl lysine acetylation GO:0018393 2 0.012
antimicrobial humoral response GO:0019730 2 0.012
retina development in camera type eye GO:0060041 146 0.012
response to oxygen containing compound GO:1901700 55 0.012
gastrulation GO:0007369 208 0.012
angiogenesis GO:0001525 158 0.012
female gonad development GO:0008585 4 0.012
synaptic vesicle transport GO:0048489 1 0.012
complement activation GO:0006956 3 0.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.012
response to external biotic stimulus GO:0043207 97 0.012
response to alkaloid GO:0043279 2 0.012
growth GO:0040007 174 0.012
regulation of ph GO:0006885 3 0.012
regulation of transporter activity GO:0032409 2 0.012
water homeostasis GO:0030104 4 0.012
negative regulation of cellular catabolic process GO:0031330 3 0.012
lateral inhibition GO:0046331 1 0.012
cytosolic calcium ion transport GO:0060401 3 0.012
negative regulation of mapk cascade GO:0043409 4 0.012
protein complex disassembly GO:0043241 1 0.012
membrane invagination GO:0010324 1 0.012
carbohydrate biosynthetic process GO:0016051 1 0.012
g1 s transition of mitotic cell cycle GO:0000082 1 0.012
release of sequestered calcium ion into cytosol GO:0051209 3 0.012
adherens junction organization GO:0034332 4 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.012
single organism biosynthetic process GO:0044711 71 0.012
regulation of macromolecule biosynthetic process GO:0010556 225 0.012
inorganic anion transport GO:0015698 25 0.012
regulation of intracellular protein transport GO:0033157 3 0.012
actin polymerization or depolymerization GO:0008154 2 0.012
regulation of stem cell proliferation GO:0072091 2 0.012
regulation of systemic arterial blood pressure GO:0003073 1 0.012
golgi vesicle transport GO:0048193 3 0.012
synaptic vesicle localization GO:0097479 1 0.012
determination of heart left right asymmetry GO:0061371 117 0.012
positive regulation of nucleotide catabolic process GO:0030813 1 0.011
nucleoside monophosphate catabolic process GO:0009125 4 0.011
organic substance transport GO:0071702 58 0.011
regulation of gtpase activity GO:0043087 2 0.011
sleep GO:0030431 1 0.011
regulation of programmed cell death GO:0043067 101 0.011
tissue remodeling GO:0048771 4 0.011
embryonic heart tube morphogenesis GO:0003143 108 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.011
actin filament polymerization GO:0030041 2 0.011
regulation of cellular protein catabolic process GO:1903362 1 0.011
regulation of apoptotic process GO:0042981 98 0.011
regulation of rna biosynthetic process GO:2001141 213 0.011
regulation of neural precursor cell proliferation GO:2000177 3 0.011
death GO:0016265 121 0.011
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.011
endocrine hormone secretion GO:0060986 2 0.011
positive regulation of nucleoside metabolic process GO:0045979 1 0.011
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.011
cell substrate adhesion GO:0031589 4 0.011
positive regulation of apoptotic signaling pathway GO:2001235 1 0.011
digestive tract development GO:0048565 265 0.011
neuromuscular synaptic transmission GO:0007274 2 0.011
regulation of sodium ion transport GO:0002028 2 0.011
mechanosensory behavior GO:0007638 2 0.011
regulation of nucleocytoplasmic transport GO:0046822 2 0.011
phagocytosis engulfment GO:0006911 1 0.011
negative regulation of cytokine production GO:0001818 1 0.011
enzyme linked receptor protein signaling pathway GO:0007167 106 0.011
skeletal system development GO:0001501 181 0.011
establishment of synaptic vesicle localization GO:0097480 1 0.011
regulation of mrna splicing via spliceosome GO:0048024 3 0.011
gas transport GO:0015669 3 0.011
cytoplasm organization GO:0007028 4 0.011
peptide metabolic process GO:0006518 1 0.011
regulation of localization GO:0032879 104 0.011
organism emergence from protective structure GO:0071684 4 0.011
germ line stem cell maintenance GO:0030718 2 0.011
macroautophagy GO:0016236 1 0.011
cell motility GO:0048870 244 0.011
positive regulation of multi organism process GO:0043902 3 0.011
muscle structure development GO:0061061 196 0.011
intracellular signal transduction GO:0035556 85 0.011
regulation of protein polymerization GO:0032271 2 0.011
stem cell division GO:0017145 1 0.011
inner ear development GO:0048839 126 0.011
acylglycerol homeostasis GO:0055090 2 0.011
protein stabilization GO:0050821 2 0.011
positive regulation of leukocyte mediated cytotoxicity GO:0001912 1 0.011
regulation of transmembrane transporter activity GO:0022898 2 0.010
cellular component assembly GO:0022607 170 0.010
regulation of cell death GO:0010941 103 0.010
regulation of cell differentiation GO:0045595 142 0.010
multi organism process GO:0051704 134 0.010
hematopoietic or lymphoid organ development GO:0048534 191 0.010
purine nucleoside monophosphate catabolic process GO:0009128 4 0.010
positive regulation of gtpase activity GO:0043547 1 0.010
phosphate containing compound metabolic process GO:0006796 108 0.010
positive regulation of camp biosynthetic process GO:0030819 2 0.010
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.010
fatty acid transport GO:0015908 1 0.010
epithelial cell differentiation GO:0030855 116 0.010
spermatid development GO:0007286 2 0.010
meiotic nuclear division GO:0007126 4 0.010
somitogenesis GO:0001756 87 0.010
establishment of localization in cell GO:0051649 77 0.010
positive regulation of epithelial cell migration GO:0010634 2 0.010
regulation of protein targeting GO:1903533 2 0.010

LOC560057 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.037
nervous system disease DOID:863 0 0.021
musculoskeletal system disease DOID:17 0 0.019
disease of metabolism DOID:0014667 0 0.014
disease of cellular proliferation DOID:14566 0 0.012
cancer DOID:162 0 0.012
organ system cancer DOID:0050686 0 0.010