Danio rerio

0 known processes

sc:d0316

sc:d0316

sc:d0316 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cellular macromolecule metabolic process GO:0044260 391 0.102
aging GO:0007568 2 0.068
larval development GO:0002164 2 0.055
organic substance biosynthetic process GO:1901576 289 0.052
biosynthetic process GO:0009058 294 0.052
nucleobase containing compound biosynthetic process GO:0034654 205 0.049
cellular biosynthetic process GO:0044249 286 0.048
embryonic organ development GO:0048568 381 0.045
positive regulation of transport GO:0051050 2 0.045
heterocycle biosynthetic process GO:0018130 215 0.044
aromatic compound biosynthetic process GO:0019438 217 0.044
regulation of cell shape GO:0008360 1 0.042
response to chemical GO:0042221 320 0.041
regulation of macromolecule biosynthetic process GO:0010556 225 0.040
regulation of metabolic process GO:0019222 359 0.040
cellular nitrogen compound metabolic process GO:0034641 290 0.040
transcription dna templated GO:0006351 181 0.040
maintenance of location GO:0051235 4 0.039
leukocyte proliferation GO:0070661 1 0.038
locomotion GO:0040011 313 0.038
cellular component morphogenesis GO:0032989 336 0.038
Human
organic cyclic compound metabolic process GO:1901360 301 0.038
cell substrate adhesion GO:0031589 4 0.037
regulation of transcription dna templated GO:0006355 213 0.037
signal transduction GO:0007165 455 0.036
phagocytosis GO:0006909 3 0.036
nucleobase containing compound metabolic process GO:0006139 274 0.035
startle response GO:0001964 4 0.035
lipid catabolic process GO:0016042 4 0.035
cellular nitrogen compound biosynthetic process GO:0044271 218 0.034
heterocycle metabolic process GO:0046483 290 0.034
regulation of protein targeting GO:1903533 2 0.034
response to glucose GO:0009749 3 0.034
macromolecule biosynthetic process GO:0009059 227 0.034
amine metabolic process GO:0009308 2 0.034
regulation of cellular metabolic process GO:0031323 320 0.034
regulation of multicellular organism growth GO:0040014 4 0.033
central nervous system development GO:0007417 387 0.033
nitrogen compound metabolic process GO:0006807 319 0.033
regulation of primary metabolic process GO:0080090 311 0.032
positive regulation of cell cycle GO:0045787 3 0.032
response to carbohydrate GO:0009743 3 0.032
cell projection organization GO:0030030 284 0.032
Human
rna biosynthetic process GO:0032774 181 0.032
response to external stimulus GO:0009605 264 0.032
nucleic acid templated transcription GO:0097659 181 0.031
lipid storage GO:0019915 1 0.031
neuron differentiation GO:0030182 353 0.031
Human
lymphocyte proliferation GO:0046651 1 0.030
immune system process GO:0002376 241 0.030
cellular macromolecule biosynthetic process GO:0034645 224 0.030
regulation of biosynthetic process GO:0009889 250 0.030
nuclear import GO:0051170 3 0.030
protein localization to nucleus GO:0034504 3 0.030
regulation of rna metabolic process GO:0051252 224 0.030
response to monosaccharide GO:0034284 3 0.030
embryonic skeletal joint morphogenesis GO:0060272 3 0.030
single organism localization GO:1902578 225 0.029
transport GO:0006810 220 0.029
peptidyl serine phosphorylation GO:0018105 1 0.029
cellular response to extracellular stimulus GO:0031668 2 0.029
regulation of autophagy GO:0010506 3 0.029
single organism transport GO:0044765 206 0.029
regulation of developmental process GO:0050793 247 0.028
Human
cellular aromatic compound metabolic process GO:0006725 295 0.028
mononuclear cell proliferation GO:0032943 1 0.028
response to drug GO:0042493 3 0.028
regulation of cellular biosynthetic process GO:0031326 245 0.028
cellular response to nutrient levels GO:0031669 2 0.028
response to hexose GO:0009746 3 0.028
cell surface receptor signaling pathway GO:0007166 325 0.028
eye development GO:0001654 277 0.028
secondary metabolic process GO:0019748 3 0.028
establishment of protein localization to organelle GO:0072594 4 0.028
regulation of cell matrix adhesion GO:0001952 1 0.027
regulation of cell activation GO:0050865 1 0.027
brain development GO:0007420 293 0.027
head development GO:0060322 303 0.027
vasculature development GO:0001944 278 0.027
nuclear transport GO:0051169 4 0.027
organic cyclic compound biosynthetic process GO:1901362 223 0.027
negative regulation of biological process GO:0048519 304 0.027
sensory organ development GO:0007423 393 0.027
regulation of multicellular organismal process GO:0051239 277 0.026
Human
regionalization GO:0003002 274 0.026
protein targeting to nucleus GO:0044744 3 0.026
response to nutrient GO:0007584 3 0.026
cell morphogenesis GO:0000902 289 0.026
Human
protein metabolic process GO:0019538 183 0.026
cellular ketone metabolic process GO:0042180 11 0.026
glucose homeostasis GO:0042593 1 0.026
cellular response to external stimulus GO:0071496 2 0.026
nucleic acid metabolic process GO:0090304 244 0.026
regulation of intracellular protein transport GO:0033157 3 0.026
establishment of localization GO:0051234 244 0.026
positive regulation of cellular component biogenesis GO:0044089 3 0.026
regulation of nucleic acid templated transcription GO:1903506 213 0.026
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.025
multicellular organism growth GO:0035264 4 0.025
regulation of metal ion transport GO:0010959 4 0.025
regulation of cellular ketone metabolic process GO:0010565 7 0.025
protein import GO:0017038 3 0.025
cell matrix adhesion GO:0007160 4 0.025
regulation of biological quality GO:0065008 263 0.025
regulation of transmembrane transporter activity GO:0022898 2 0.024
regulation of establishment of protein localization GO:0070201 4 0.024
establishment of protein localization to plasma membrane GO:0090002 1 0.024
axon midline choice point recognition GO:0016199 4 0.024
positive regulation of cellular catabolic process GO:0031331 3 0.024
cellular component movement GO:0006928 335 0.023
primary neural tube formation GO:0014020 1 0.023
response to alkaloid GO:0043279 2 0.023
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.023
cell migration GO:0016477 237 0.023
regulation of cytoplasmic transport GO:1903649 4 0.023
regulation of response to stimulus GO:0048583 269 0.022
gene expression GO:0010467 252 0.022
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.022
cellular amine metabolic process GO:0044106 2 0.022
cellular response to chemical stimulus GO:0070887 157 0.022
regulation of cytokine production GO:0001817 3 0.022
regulation of protein transport GO:0051223 3 0.022
rna metabolic process GO:0016070 219 0.021
regulation of cell substrate adhesion GO:0010810 1 0.021
nucleocytoplasmic transport GO:0006913 4 0.021
regulation of cell projection assembly GO:0060491 4 0.021
positive regulation of catabolic process GO:0009896 4 0.021
regulation of production of molecular mediator of immune response GO:0002700 1 0.021
regulation of cellular amino acid metabolic process GO:0006521 0 0.021
gtp catabolic process GO:0006184 2 0.021
regulation of macromolecule metabolic process GO:0060255 317 0.021
carboxylic acid metabolic process GO:0019752 22 0.021
transcription from rna polymerase ii promoter GO:0006366 80 0.021
regulation of signaling GO:0023051 235 0.021
adult behavior GO:0030534 2 0.020
negative regulation of sequestering of calcium ion GO:0051283 4 0.020
regulation of ion transmembrane transporter activity GO:0032412 2 0.020
peptidyl threonine phosphorylation GO:0018107 1 0.020
melanin metabolic process GO:0006582 2 0.020
chordate embryonic development GO:0043009 271 0.020
connective tissue development GO:0061448 99 0.020
developmental growth GO:0048589 166 0.019
inner ear development GO:0048839 126 0.019
carbohydrate homeostasis GO:0033500 1 0.019
female sex differentiation GO:0046660 4 0.019
positive regulation of cytoskeleton organization GO:0051495 3 0.019
generation of neurons GO:0048699 385 0.019
Human
stem cell proliferation GO:0072089 4 0.019
regulation of rna biosynthetic process GO:2001141 213 0.019
regulation of anatomical structure morphogenesis GO:0022603 130 0.019
Human
regulation of cell development GO:0060284 100 0.019
Human
female gonad development GO:0008585 4 0.019
regulation of cell communication GO:0010646 232 0.019
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.019
regulation of protein localization to nucleus GO:1900180 2 0.019
retina development in camera type eye GO:0060041 146 0.019
cell morphogenesis involved in differentiation GO:0000904 195 0.019
Human
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.019
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.018
cell part morphogenesis GO:0032990 246 0.018
Human
embryonic skeletal joint development GO:0072498 3 0.018
positive regulation of immune effector process GO:0002699 3 0.018
blood vessel development GO:0001568 246 0.018
peptide transport GO:0015833 1 0.018
protein localization to plasma membrane GO:0072659 1 0.018
embryonic organ morphogenesis GO:0048562 274 0.018
guanosine containing compound catabolic process GO:1901069 2 0.018
digestive tract development GO:0048565 265 0.018
specification of symmetry GO:0009799 204 0.018
protein import into nucleus GO:0006606 3 0.018
morphogenesis of an epithelium GO:0002009 333 0.018
regulation of protein import into nucleus GO:0042306 2 0.018
transmission of nerve impulse GO:0019226 19 0.018
gtp metabolic process GO:0046039 4 0.018
cell projection morphogenesis GO:0048858 244 0.018
Human
peptidyl serine modification GO:0018209 2 0.018
protein targeting to membrane GO:0006612 1 0.018
cell motility GO:0048870 244 0.018
regulation of cyclase activity GO:0031279 12 0.018
defense response to fungus GO:0050832 2 0.018
cellular response to oxygen levels GO:0071453 1 0.018
cellular response to organic substance GO:0071310 105 0.018
tube morphogenesis GO:0035239 349 0.017
guanosine containing compound metabolic process GO:1901068 4 0.017
axon development GO:0061564 166 0.017
Human
protein secretion GO:0009306 1 0.017
cellular response to starvation GO:0009267 1 0.017
regulation of mrna processing GO:0050684 3 0.017
regulation of transporter activity GO:0032409 2 0.017
negative regulation of cellular process GO:0048523 283 0.017
positive regulation of cell adhesion GO:0045785 1 0.017
organonitrogen compound metabolic process GO:1901564 74 0.017
sequestering of metal ion GO:0051238 3 0.017
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.016
regulation of sequestering of calcium ion GO:0051282 4 0.016
regulation of cellular amine metabolic process GO:0033238 0 0.016
regulation of nucleocytoplasmic transport GO:0046822 2 0.016
organic acid metabolic process GO:0006082 31 0.016
negative regulation of secretion by cell GO:1903531 2 0.016
chemotaxis GO:0006935 104 0.016
homeostatic process GO:0042592 142 0.016
regulation of synapse organization GO:0050807 3 0.016
regulation of dendrite development GO:0050773 3 0.016
response to stress GO:0006950 263 0.016
peptidyl threonine modification GO:0018210 1 0.016
positive regulation of secretion GO:0051047 1 0.016
outflow tract morphogenesis GO:0003151 1 0.016
response to organic substance GO:0010033 153 0.016
skeletal system development GO:0001501 181 0.016
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.016
golgi vesicle transport GO:0048193 3 0.015
tissue remodeling GO:0048771 4 0.015
hormone secretion GO:0046879 2 0.015
negative regulation of cellular catabolic process GO:0031330 3 0.015
axonogenesis GO:0007409 152 0.015
Human
single organism nuclear import GO:1902593 3 0.015
regulation of calcium ion transport GO:0051924 2 0.015
positive regulation of cellular amine metabolic process GO:0033240 0 0.015
macroautophagy GO:0016236 1 0.015
regeneration GO:0031099 91 0.015
synaptic target recognition GO:0008039 1 0.015
positive regulation of nucleoside metabolic process GO:0045979 1 0.015
hepaticobiliary system development GO:0061008 98 0.015
digestive system development GO:0055123 289 0.015
sensory organ morphogenesis GO:0090596 200 0.015
positive regulation of cell substrate adhesion GO:0010811 1 0.015
regulation of protein complex assembly GO:0043254 3 0.015
response to glucocorticoid GO:0051384 1 0.015
action potential GO:0001508 19 0.015
liver development GO:0001889 96 0.015
angiogenesis GO:0001525 158 0.015
regulation of meiotic cell cycle GO:0051445 1 0.015
negative chemotaxis GO:0050919 1 0.015
negative regulation of catabolic process GO:0009895 3 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.014
i kappab kinase nf kappab signaling GO:0007249 4 0.014
localization of cell GO:0051674 244 0.014
gastrulation GO:0007369 208 0.014
sequestering of calcium ion GO:0051208 3 0.014
regulation of localization GO:0032879 104 0.014
regulation of nitrogen compound metabolic process GO:0051171 251 0.014
regulation of reproductive process GO:2000241 4 0.014
positive regulation of gtpase activity GO:0043547 1 0.014
exocytosis GO:0006887 1 0.014
negative regulation of response to stimulus GO:0048585 104 0.014
ear development GO:0043583 127 0.014
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.014
negative regulation of cytoplasmic transport GO:1903650 2 0.014
heart development GO:0007507 313 0.014
negative regulation of protein import into nucleus GO:0042308 2 0.014
positive regulation of nucleotide catabolic process GO:0030813 1 0.014
camera type eye development GO:0043010 222 0.014
response to corticosteroid GO:0031960 1 0.014
transmembrane transport GO:0055085 120 0.014
negative regulation of dna metabolic process GO:0051053 4 0.014
ubiquitin dependent protein catabolic process GO:0006511 3 0.014
digestive tract morphogenesis GO:0048546 231 0.014
negative regulation of intracellular transport GO:0032387 3 0.014
cognition GO:0050890 1 0.014
antimicrobial humoral response GO:0019730 2 0.014
regulation of filopodium assembly GO:0051489 2 0.014
actin polymerization or depolymerization GO:0008154 2 0.014
developmental cell growth GO:0048588 52 0.014
small molecule catabolic process GO:0044282 3 0.013
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.013
regulation of muscle contraction GO:0006937 3 0.013
cellular component assembly GO:0022607 170 0.013
negative regulation of cell communication GO:0010648 96 0.013
regulation of synapse assembly GO:0051963 3 0.013
regulation of gene expression GO:0010468 265 0.013
regulation of ph GO:0006885 3 0.013
production of molecular mediator of immune response GO:0002440 2 0.013
embryonic skeletal system development GO:0048706 97 0.013
cellular amino acid metabolic process GO:0006520 7 0.013
anterior posterior pattern specification GO:0009952 152 0.013
positive regulation of gtp catabolic process GO:0033126 1 0.013
regulation of protein ubiquitination GO:0031396 3 0.013
positive regulation of ras protein signal transduction GO:0046579 1 0.013
regulation of cell differentiation GO:0045595 142 0.013
Human
neuron neuron synaptic transmission GO:0007270 1 0.013
release of sequestered calcium ion into cytosol GO:0051209 3 0.013
taxis GO:0042330 109 0.013
smooth muscle contraction GO:0006939 2 0.013
neuron development GO:0048666 262 0.013
Human
cellular component biogenesis GO:0044085 178 0.013
regulation of rho protein signal transduction GO:0035023 2 0.013
stem cell differentiation GO:0048863 117 0.013
epithelial tube morphogenesis GO:0060562 148 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.013
small molecule metabolic process GO:0044281 77 0.013
regulation of response to biotic stimulus GO:0002831 2 0.013
pancreas development GO:0031016 84 0.013
regulation of purine nucleotide catabolic process GO:0033121 2 0.013
nuclear migration GO:0007097 3 0.013
regulation of gtp catabolic process GO:0033124 2 0.013
response to transition metal nanoparticle GO:1990267 28 0.013
regulation of wnt signaling pathway GO:0030111 53 0.013
regulation of multicellular organismal development GO:2000026 223 0.013
Human
cation transmembrane transport GO:0098655 65 0.013
regulation of carbohydrate metabolic process GO:0006109 4 0.013
growth GO:0040007 174 0.013
hematopoietic or lymphoid organ development GO:0048534 191 0.013
negative regulation of protein transport GO:0051224 3 0.013
lamellipodium assembly GO:0030032 1 0.012
positive regulation of cellular process GO:0048522 201 0.012
cellular carbohydrate metabolic process GO:0044262 4 0.012
macromolecule modification GO:0043412 111 0.012
regulation of circadian rhythm GO:0042752 4 0.012
hatching GO:0035188 4 0.012
rna localization GO:0006403 4 0.012
stem cell maintenance GO:0019827 4 0.012
axon guidance GO:0007411 86 0.012
interspecies interaction between organisms GO:0044419 4 0.012
gland development GO:0048732 143 0.012
central nervous system neuron differentiation GO:0021953 74 0.012
phagocytosis engulfment GO:0006911 1 0.012
oxoacid metabolic process GO:0043436 31 0.012
regulation of dendrite morphogenesis GO:0048814 3 0.012
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.012
Human
cellular localization GO:0051641 97 0.012
regulation of cellular component organization GO:0051128 86 0.012
Human
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.012
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 4 0.012
regulation of biomineral tissue development GO:0070167 2 0.012
regulation of glial cell differentiation GO:0045685 4 0.012
synaptic growth at neuromuscular junction GO:0051124 2 0.012
medulla oblongata development GO:0021550 4 0.012
modification dependent protein catabolic process GO:0019941 3 0.012
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.012
regulation of tube size GO:0035150 2 0.012
regulation of neurogenesis GO:0050767 87 0.012
Human
positive regulation of cell activation GO:0050867 1 0.012
tube closure GO:0060606 1 0.012
endosomal transport GO:0016197 2 0.012
single organism metabolic process GO:0044710 217 0.012
positive regulation of biological process GO:0048518 253 0.012
neuron projection morphogenesis GO:0048812 161 0.012
Human
negative regulation of protein localization to nucleus GO:1900181 2 0.012
calcium ion transport into cytosol GO:0060402 3 0.012
somatic muscle development GO:0007525 4 0.012
ion transmembrane transport GO:0034220 91 0.012
embryo development ending in birth or egg hatching GO:0009792 271 0.012
positive regulation of metabolic process GO:0009893 108 0.011
protein modification process GO:0036211 100 0.011
cellular lipid catabolic process GO:0044242 3 0.011
protein acetylation GO:0006473 2 0.011
hemopoiesis GO:0030097 183 0.011
cellular amide metabolic process GO:0043603 4 0.011
actin filament based movement GO:0030048 1 0.011
developmental growth involved in morphogenesis GO:0060560 86 0.011
meiotic nuclear division GO:0007126 4 0.011
cellular protein metabolic process GO:0044267 129 0.011
entrainment of circadian clock GO:0009649 2 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.011
cellular response to hypoxia GO:0071456 1 0.011
compound eye development GO:0048749 2 0.011
gastrulation with mouth forming second GO:0001702 44 0.011
cartilage development GO:0051216 96 0.011
negative regulation of signaling GO:0023057 96 0.011
response to ketone GO:1901654 1 0.011
post embryonic organ development GO:0048569 4 0.011
alcohol biosynthetic process GO:0046165 2 0.011
organism emergence from protective structure GO:0071684 4 0.011
rhombomere 5 development GO:0021571 4 0.011
system process GO:0003008 185 0.011
internal protein amino acid acetylation GO:0006475 2 0.011
regulation of nucleotide catabolic process GO:0030811 2 0.011
sleep GO:0030431 1 0.011
modification dependent macromolecule catabolic process GO:0043632 3 0.011
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.011
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.011
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.011
protein homooligomerization GO:0051260 3 0.011
wnt signaling pathway GO:0016055 80 0.010
wound healing GO:0042060 90 0.010
one carbon compound transport GO:0019755 14 0.010
skeletal system morphogenesis GO:0048705 102 0.010
regulation of gtpase activity GO:0043087 2 0.010
proteasomal protein catabolic process GO:0010498 2 0.010
immune system development GO:0002520 191 0.010
mitochondrion organization GO:0007005 4 0.010
regulation of cell migration GO:0030334 40 0.010
renal tubule morphogenesis GO:0061333 1 0.010
lipid oxidation GO:0034440 1 0.010
dorsal motor nucleus of vagus nerve development GO:0021744 4 0.010
membrane invagination GO:0010324 1 0.010
regulation of protein complex disassembly GO:0043244 1 0.010
positive regulation of stress activated mapk cascade GO:0032874 3 0.010
cytosolic calcium ion transport GO:0060401 3 0.010
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.010

sc:d0316 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.049
cardiovascular system disease DOID:1287 0 0.022
musculoskeletal system disease DOID:17 0 0.015
cancer DOID:162 0 0.015
disease of cellular proliferation DOID:14566 0 0.015
organ system cancer DOID:0050686 0 0.014