Danio rerio

8 known processes

fitm2

fat storage-inducing transmembrane protein 2

(Aliases: wu:fc04g08,fit2,zgc:110840,wu:fr13b05)

fitm2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.094
maintenance of location GO:0051235 4 0.064
aging GO:0007568 2 0.051
cognition GO:0050890 1 0.043
multicellular organism growth GO:0035264 4 0.038
lipid storage GO:0019915 1 0.038
regulation of muscle contraction GO:0006937 3 0.038
regulation of multicellular organism growth GO:0040014 4 0.037
neurotransmitter transport GO:0006836 2 0.035
phagocytosis GO:0006909 3 0.034
pole plasm assembly GO:0007315 4 0.033
positive regulation of transport GO:0051050 2 0.033
regionalization GO:0003002 274 0.033
signal transduction GO:0007165 455 0.032
regulation of biological quality GO:0065008 263 0.032
rna localization GO:0006403 4 0.029
post embryonic organ development GO:0048569 4 0.029
actin filament based movement GO:0030048 1 0.028
mitochondrion organization GO:0007005 4 0.028
guanosine containing compound catabolic process GO:1901069 2 0.027
regulation of signaling GO:0023051 235 0.026
actin polymerization or depolymerization GO:0008154 2 0.026
regulation of metal ion transport GO:0010959 4 0.025
regulation of protein complex assembly GO:0043254 3 0.025
regulation of ion transmembrane transporter activity GO:0032412 2 0.025
locomotion GO:0040011 313 0.024
nucleobase containing compound metabolic process GO:0006139 274 0.024
cellular response to lipopolysaccharide GO:0071222 3 0.024
somatic muscle development GO:0007525 4 0.023
cellular component movement GO:0006928 335 0.023
negative regulation of biological process GO:0048519 304 0.023
regulation of blood pressure GO:0008217 1 0.023
cellular aromatic compound metabolic process GO:0006725 295 0.023
neurotransmitter secretion GO:0007269 2 0.023
biosynthetic process GO:0009058 294 0.023
response to alkaloid GO:0043279 2 0.023
regulation of signal transduction GO:0009966 225 0.023
regulation of cell communication GO:0010646 232 0.022
positive regulation of cellular catabolic process GO:0031331 3 0.022
positive regulation of cellular component biogenesis GO:0044089 3 0.022
amine metabolic process GO:0009308 2 0.022
nitrogen compound metabolic process GO:0006807 319 0.022
regulation of establishment of protein localization GO:0070201 4 0.022
nucleoside monophosphate catabolic process GO:0009125 4 0.021
cell migration GO:0016477 237 0.021
localization of cell GO:0051674 244 0.021
regulation of cell activation GO:0050865 1 0.021
regulation of transmembrane transporter activity GO:0022898 2 0.021
modification dependent protein catabolic process GO:0019941 3 0.021
intracellular mrna localization GO:0008298 1 0.021
regulation of cytokine production GO:0001817 3 0.021
establishment of protein localization to organelle GO:0072594 4 0.021
regulation of neural precursor cell proliferation GO:2000177 3 0.021
cellular response to external stimulus GO:0071496 2 0.021
meiotic cell cycle process GO:1903046 3 0.020
cellular response to nutrient levels GO:0031669 2 0.020
synaptic growth at neuromuscular junction GO:0051124 2 0.020
negative regulation of sequestering of calcium ion GO:0051283 4 0.020
proteasomal protein catabolic process GO:0010498 2 0.020
muscle cell differentiation GO:0042692 139 0.020
homeostatic process GO:0042592 142 0.020
sensory perception of chemical stimulus GO:0007606 3 0.020
membrane fusion GO:0061025 2 0.019
cellular nitrogen compound metabolic process GO:0034641 290 0.019
positive regulation of cell cycle GO:0045787 3 0.019
regulation of cell shape GO:0008360 1 0.019
organic substance biosynthetic process GO:1901576 289 0.019
positive regulation of catabolic process GO:0009896 4 0.019
response to chemical GO:0042221 320 0.019
cytoplasm organization GO:0007028 4 0.019
adult behavior GO:0030534 2 0.019
meiotic nuclear division GO:0007126 4 0.019
regulation of metabolic process GO:0019222 359 0.019
stem cell maintenance GO:0019827 4 0.018
maternal determination of anterior posterior axis embryo GO:0008358 4 0.018
response to drug GO:0042493 3 0.018
single organism metabolic process GO:0044710 217 0.018
cell motility GO:0048870 244 0.018
regulation of binding GO:0051098 3 0.018
oocyte anterior posterior axis specification GO:0007314 4 0.018
gtp catabolic process GO:0006184 2 0.018
sequestering of metal ion GO:0051238 3 0.018
modification dependent macromolecule catabolic process GO:0043632 3 0.018
single organism membrane fusion GO:0044801 2 0.018
chemosensory behavior GO:0007635 1 0.018
muscle structure development GO:0061061 196 0.018
nucleocytoplasmic transport GO:0006913 4 0.018
exocytosis GO:0006887 1 0.018
leukocyte proliferation GO:0070661 1 0.018
tissue remodeling GO:0048771 4 0.018
nuclear transport GO:0051169 4 0.018
cellular protein catabolic process GO:0044257 4 0.017
cellular amine metabolic process GO:0044106 2 0.017
regulation of cellular amine metabolic process GO:0033238 0 0.017
cellular response to extracellular stimulus GO:0031668 2 0.017
ventricular cardiac muscle tissue development GO:0003229 3 0.017
regulation of cell projection assembly GO:0060491 4 0.017
actin filament polymerization GO:0030041 2 0.017
cellular component disassembly GO:0022411 1 0.017
locomotor rhythm GO:0045475 3 0.017
gtp metabolic process GO:0046039 4 0.017
stem cell proliferation GO:0072089 4 0.017
cellular biosynthetic process GO:0044249 286 0.017
digestive system development GO:0055123 289 0.017
cellular response to biotic stimulus GO:0071216 3 0.017
cellular nitrogen compound biosynthetic process GO:0044271 218 0.017
endosomal transport GO:0016197 2 0.017
protein polymerization GO:0051258 4 0.017
positive regulation of cytoskeleton organization GO:0051495 3 0.017
protein localization to plasma membrane GO:0072659 1 0.017
neuroblast proliferation GO:0007405 2 0.017
organic acid metabolic process GO:0006082 31 0.017
sleep GO:0030431 1 0.017
protein targeting to nucleus GO:0044744 3 0.017
cellular response to starvation GO:0009267 1 0.017
protein complex disassembly GO:0043241 1 0.017
protein import into nucleus GO:0006606 3 0.017
negative regulation of protein kinase activity GO:0006469 4 0.016
regulation of reproductive process GO:2000241 4 0.016
regulation of sodium ion transport GO:0002028 2 0.016
b cell activation GO:0042113 2 0.016
regulation of transporter activity GO:0032409 2 0.016
regulation of response to stimulus GO:0048583 269 0.016
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.016
regulation of protein polymerization GO:0032271 2 0.016
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.016
establishment of localization GO:0051234 244 0.016
regulation of synapse organization GO:0050807 3 0.016
membrane invagination GO:0010324 1 0.016
purine nucleoside monophosphate catabolic process GO:0009128 4 0.016
embryonic organ development GO:0048568 381 0.016
cellular macromolecule metabolic process GO:0044260 391 0.016
regulation of macromolecule metabolic process GO:0060255 317 0.016
ubiquitin dependent protein catabolic process GO:0006511 3 0.016
nucleic acid templated transcription GO:0097659 181 0.016
single organism nuclear import GO:1902593 3 0.015
cellular ketone metabolic process GO:0042180 11 0.015
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.015
regulation of synaptic plasticity GO:0048167 1 0.015
gene expression GO:0010467 252 0.015
macromolecular complex disassembly GO:0032984 1 0.015
negative regulation of cellular process GO:0048523 283 0.015
regulation of synapse assembly GO:0051963 3 0.015
synaptic transmission cholinergic GO:0007271 4 0.015
spermatid development GO:0007286 2 0.015
negative regulation of protein phosphorylation GO:0001933 4 0.015
peptidyl lysine acetylation GO:0018394 2 0.015
death GO:0016265 121 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
regulation of sequestering of calcium ion GO:0051282 4 0.015
regulation of cellular ketone metabolic process GO:0010565 7 0.015
cellular response to chemical stimulus GO:0070887 157 0.015
single organism localization GO:1902578 225 0.015
antimicrobial humoral response GO:0019730 2 0.015
regulation of nucleic acid templated transcription GO:1903506 213 0.015
single fertilization GO:0007338 3 0.015
synaptic vesicle localization GO:0097479 1 0.015
nuclear import GO:0051170 3 0.015
regulation of protein transport GO:0051223 3 0.015
regulation of stem cell proliferation GO:0072091 2 0.015
regulation of nitrogen compound metabolic process GO:0051171 251 0.015
aromatic compound biosynthetic process GO:0019438 217 0.015
heterocycle metabolic process GO:0046483 290 0.015
oxoacid metabolic process GO:0043436 31 0.015
guanosine containing compound metabolic process GO:1901068 4 0.015
skeletal system development GO:0001501 181 0.015
internal peptidyl lysine acetylation GO:0018393 2 0.015
protein import GO:0017038 3 0.014
organelle organization GO:0006996 227 0.014
regulation of rho protein signal transduction GO:0035023 2 0.014
establishment of synaptic vesicle localization GO:0097480 1 0.014
regulation of macromolecule biosynthetic process GO:0010556 225 0.014
cellular amino acid metabolic process GO:0006520 7 0.014
immune system process GO:0002376 241 0.014
nucleic acid metabolic process GO:0090304 244 0.014
dicarboxylic acid transport GO:0006835 1 0.014
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.014
phagocytosis engulfment GO:0006911 1 0.014
neuron neuron synaptic transmission GO:0007270 1 0.014
regulation of neurotransmitter transport GO:0051588 1 0.014
autophagy GO:0006914 4 0.014
regulation of cytoplasmic transport GO:1903649 4 0.014
fertilization GO:0009566 3 0.014
regulation of ph GO:0006885 3 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.014
actin mediated cell contraction GO:0070252 1 0.014
muscle tissue development GO:0060537 110 0.014
response to stress GO:0006950 263 0.014
regulation of mrna processing GO:0050684 3 0.014
cell projection morphogenesis GO:0048858 244 0.014
regulation of rna biosynthetic process GO:2001141 213 0.014
cell morphogenesis GO:0000902 289 0.014
positive regulation of protein complex assembly GO:0031334 2 0.014
nucleobase containing compound biosynthetic process GO:0034654 205 0.014
carboxylic acid metabolic process GO:0019752 22 0.014
macromolecule biosynthetic process GO:0009059 227 0.014
regulation of protein complex disassembly GO:0043244 1 0.014
release of sequestered calcium ion into cytosol GO:0051209 3 0.014
regulation of biosynthetic process GO:0009889 250 0.014
i kappab kinase nf kappab signaling GO:0007249 4 0.014
rna metabolic process GO:0016070 219 0.014
mononuclear cell proliferation GO:0032943 1 0.014
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.013
interspecies interaction between organisms GO:0044419 4 0.013
regulation of sodium ion transmembrane transport GO:1902305 1 0.013
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.013
anterior posterior pattern specification GO:0009952 152 0.013
positive regulation of cell activation GO:0050867 1 0.013
cell projection organization GO:0030030 284 0.013
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.013
dna templated transcription elongation GO:0006354 3 0.013
ribonucleoside monophosphate catabolic process GO:0009158 4 0.013
cellular component assembly GO:0022607 170 0.013
negative regulation of protein transport GO:0051224 3 0.013
negative regulation of cytoplasmic transport GO:1903650 2 0.013
calcium ion transport into cytosol GO:0060402 3 0.013
regulation of protein import into nucleus GO:0042306 2 0.013
digestive tract morphogenesis GO:0048546 231 0.013
protein localization to nucleus GO:0034504 3 0.013
regulation of blood vessel size GO:0050880 2 0.013
cartilage development GO:0051216 96 0.013
protein acylation GO:0043543 3 0.013
synaptic vesicle transport GO:0048489 1 0.013
organelle fusion GO:0048284 3 0.013
regulation of nucleoside metabolic process GO:0009118 2 0.013
peptide transport GO:0015833 1 0.013
smooth muscle contraction GO:0006939 2 0.012
cellular response to organic substance GO:0071310 105 0.012
regulation of protein targeting GO:1903533 2 0.012
muscle organ development GO:0007517 101 0.012
positive regulation of cellular amine metabolic process GO:0033240 0 0.012
transport GO:0006810 220 0.012
chemical homeostasis GO:0048878 49 0.012
cellular component biogenesis GO:0044085 178 0.012
sequestering of calcium ion GO:0051208 3 0.012
vacuolar transport GO:0007034 2 0.012
protein acetylation GO:0006473 2 0.012
regulation of autophagy GO:0010506 3 0.012
regulation of intracellular protein transport GO:0033157 3 0.012
regulation of nucleotide catabolic process GO:0030811 2 0.012
heterocycle biosynthetic process GO:0018130 215 0.012
cellular response to radiation GO:0071478 4 0.012
regulation of meiotic cell cycle GO:0051445 1 0.012
response to carbohydrate GO:0009743 3 0.012
internal protein amino acid acetylation GO:0006475 2 0.012
inositol lipid mediated signaling GO:0048017 2 0.012
regulation of stem cell differentiation GO:2000736 4 0.012
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.012
positive regulation of multi organism process GO:0043902 3 0.012
response to uv GO:0009411 3 0.012
regulation of circadian rhythm GO:0042752 4 0.012
regulation of gtpase activity GO:0043087 2 0.012
response to external stimulus GO:0009605 264 0.012
regulation of systemic arterial blood pressure GO:0003073 1 0.012
cell part morphogenesis GO:0032990 246 0.012
immune system development GO:0002520 191 0.012
regulation of tube size GO:0035150 2 0.012
regulation of cellular biosynthetic process GO:0031326 245 0.012
hormone transport GO:0009914 2 0.012
cell cycle arrest GO:0007050 1 0.012
positive regulation of secretion GO:0051047 1 0.012
protein stabilization GO:0050821 2 0.012
blood vessel development GO:0001568 246 0.012
cytosolic calcium ion transport GO:0060401 3 0.012
regulation of dna templated transcription elongation GO:0032784 3 0.012
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.012
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.012
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.012
regulation of dendrite development GO:0050773 3 0.012
cellular carbohydrate metabolic process GO:0044262 4 0.012
tube morphogenesis GO:0035239 349 0.012
cellular component morphogenesis GO:0032989 336 0.012
positive regulation of nucleoside metabolic process GO:0045979 1 0.012
negative regulation of intracellular transport GO:0032387 3 0.012
negative regulation of mapk cascade GO:0043409 4 0.012
blood vessel morphogenesis GO:0048514 216 0.012
macroautophagy GO:0016236 1 0.011
cytoskeleton dependent cytokinesis GO:0061640 3 0.011
developmental growth GO:0048589 166 0.011
establishment of protein localization to plasma membrane GO:0090002 1 0.011
lymphocyte proliferation GO:0046651 1 0.011
regulation of nucleocytoplasmic transport GO:0046822 2 0.011
positive regulation of blood circulation GO:1903524 2 0.011
regulation of dna templated transcription in response to stress GO:0043620 0 0.011
hematopoietic or lymphoid organ development GO:0048534 191 0.011
response to monosaccharide GO:0034284 3 0.011
regulation of protein localization to nucleus GO:1900180 2 0.011
positive regulation of gtp catabolic process GO:0033126 1 0.011
regulation of primary metabolic process GO:0080090 311 0.011
cytokinesis GO:0000910 3 0.011
positive regulation of dna templated transcription elongation GO:0032786 1 0.011
positive regulation of biological process GO:0048518 253 0.011
positive regulation of gtpase activity GO:0043547 1 0.011
notochord development GO:0030903 54 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.011
cell matrix adhesion GO:0007160 4 0.011
neuron differentiation GO:0030182 353 0.011
cellular response to oxygen levels GO:0071453 1 0.011
morphogenesis of an epithelium GO:0002009 333 0.011
positive regulation of cell adhesion GO:0045785 1 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.011
hemopoiesis GO:0030097 183 0.011
lipid catabolic process GO:0016042 4 0.011
regulation of gene expression GO:0010468 265 0.011
meiotic chromosome segregation GO:0045132 3 0.011
spermatid differentiation GO:0048515 2 0.011
organic cyclic compound metabolic process GO:1901360 301 0.011
positive regulation of nucleotide catabolic process GO:0030813 1 0.011
transcription from rna polymerase ii promoter GO:0006366 80 0.011
sensory organ development GO:0007423 393 0.011
regulation of cell death GO:0010941 103 0.011
regulation of myotube differentiation GO:0010830 2 0.011
vasculature development GO:0001944 278 0.011
positive regulation of secretion by cell GO:1903532 1 0.011
cellular response to hypoxia GO:0071456 1 0.011
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.011
histone h3 k4 methylation GO:0051568 2 0.011
lamellipodium assembly GO:0030032 1 0.011
alcohol biosynthetic process GO:0046165 2 0.011
cell cycle g1 s phase transition GO:0044843 1 0.011
organic cyclic compound biosynthetic process GO:1901362 223 0.011
atp catabolic process GO:0006200 4 0.011
golgi vesicle transport GO:0048193 3 0.011
response to organic substance GO:0010033 153 0.011
regulation of protein catabolic process GO:0042176 1 0.011
lipid homeostasis GO:0055088 3 0.011
positive regulation of dna metabolic process GO:0051054 1 0.010
negative regulation of catabolic process GO:0009895 3 0.010
response to hexose GO:0009746 3 0.010
cellular respiration GO:0045333 3 0.010
chemotaxis GO:0006935 104 0.010
cortical cytoskeleton organization GO:0030865 1 0.010
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.010
regulation of membrane potential GO:0042391 23 0.010
regulation of inflammatory response GO:0050727 2 0.010
central nervous system development GO:0007417 387 0.010
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.010
extrinsic apoptotic signaling pathway GO:0097191 3 0.010
single organism transport GO:0044765 206 0.010
hormone secretion GO:0046879 2 0.010
compound eye development GO:0048749 2 0.010
protein homooligomerization GO:0051260 3 0.010
protein dephosphorylation GO:0006470 3 0.010
cell death GO:0008219 121 0.010
amino acid transport GO:0006865 2 0.010
negative regulation of kinase activity GO:0033673 4 0.010
digestive tract development GO:0048565 265 0.010
rna biosynthetic process GO:0032774 181 0.010
response to wounding GO:0009611 116 0.010
small molecule metabolic process GO:0044281 77 0.010
positive regulation of immune effector process GO:0002699 3 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.010
negative regulation of neural precursor cell proliferation GO:2000178 1 0.010
cell substrate junction assembly GO:0007044 2 0.010
regulation of gtp catabolic process GO:0033124 2 0.010
single organism organelle organization GO:1902589 199 0.010
cellular macromolecule biosynthetic process GO:0034645 224 0.010
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 1 0.010

fitm2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.045
myopathy DOID:423 0 0.018
muscular disease DOID:0080000 0 0.018
musculoskeletal system disease DOID:17 0 0.018
muscle tissue disease DOID:66 0 0.018
nervous system disease DOID:863 0 0.018
disease of metabolism DOID:0014667 0 0.014
cancer DOID:162 0 0.010
disease of cellular proliferation DOID:14566 0 0.010