Danio rerio

21 known processes

chaf1b

chromatin assembly factor 1, subunit B

(Aliases: wu:fd07c09,zgc:56096,wu:fe36g06,wu:fv38g09)

chaf1b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
meiotic chromosome segregation GO:0045132 3 0.634
embryo development ending in birth or egg hatching GO:0009792 271 0.475
Worm
meiotic nuclear division GO:0007126 4 0.458
sensory organ morphogenesis GO:0090596 200 0.435
mitotic dna integrity checkpoint GO:0044774 4 0.397
eye development GO:0001654 277 0.370
cellular macromolecule metabolic process GO:0044260 391 0.364
Human Yeast
purine nucleoside monophosphate catabolic process GO:0009128 4 0.362
eye morphogenesis GO:0048592 144 0.334
ribonucleoside monophosphate catabolic process GO:0009158 4 0.300
cell projection morphogenesis GO:0048858 244 0.287
camera type eye morphogenesis GO:0048593 108 0.284
meiotic cell cycle process GO:1903046 3 0.246
positive regulation of cellular metabolic process GO:0031325 94 0.244
atp catabolic process GO:0006200 4 0.234
larval development GO:0002164 2 0.233
nitrogen compound metabolic process GO:0006807 319 0.224
Human Yeast
retina morphogenesis in camera type eye GO:0060042 79 0.217
retina layer formation GO:0010842 24 0.210
regulation of multicellular organismal development GO:2000026 223 0.208
locomotion GO:0040011 313 0.208
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.205
microtubule organizing center organization GO:0031023 1 0.201
nucleoside monophosphate catabolic process GO:0009125 4 0.193
regulation of multicellular organismal process GO:0051239 277 0.190
meiosis i GO:0007127 1 0.185
cellular respiration GO:0045333 3 0.177
double strand break repair via homologous recombination GO:0000724 1 0.168
retina development in camera type eye GO:0060041 146 0.163
reciprocal dna recombination GO:0035825 1 0.162
centrosome cycle GO:0007098 1 0.157
histone h3 k9 modification GO:0061647 5 0.157
regulation of cellular metabolic process GO:0031323 320 0.144
centrosome organization GO:0051297 1 0.141
sensory organ development GO:0007423 393 0.140
reciprocal meiotic recombination GO:0007131 1 0.136
cellular response to chemical stimulus GO:0070887 157 0.134
macromolecule biosynthetic process GO:0009059 227 0.125
positive regulation of cellular catabolic process GO:0031331 3 0.122
cellular nitrogen compound metabolic process GO:0034641 290 0.118
Human Yeast
g2 dna damage checkpoint GO:0031572 3 0.118
negative regulation of cellular process GO:0048523 283 0.117
response to chemical GO:0042221 320 0.115
regulation of metabolic process GO:0019222 359 0.115
primary neural tube formation GO:0014020 1 0.114
nuclear division GO:0000280 23 0.113
centrosome duplication GO:0051298 1 0.113
mitotic g2 m transition checkpoint GO:0044818 3 0.109
mitotic g2 dna damage checkpoint GO:0007095 3 0.108
nucleic acid metabolic process GO:0090304 244 0.108
Human Yeast
double strand break repair GO:0006302 3 0.106
camera type eye development GO:0043010 222 0.105
mitotic nuclear division GO:0007067 18 0.104
mitotic sister chromatid segregation GO:0000070 6 0.101
regulation of macromolecule metabolic process GO:0060255 317 0.099
cellular response to endogenous stimulus GO:0071495 68 0.098
neural retina development GO:0003407 49 0.098
organelle organization GO:0006996 227 0.095
Human Yeast
digestive system development GO:0055123 289 0.093
regulation of dna replication GO:0006275 3 0.092
nuclear pore complex assembly GO:0051292 2 0.086
cellular macromolecule biosynthetic process GO:0034645 224 0.086
mitotic dna damage checkpoint GO:0044773 4 0.085
regulation of developmental process GO:0050793 247 0.085
regulation of multicellular organism growth GO:0040014 4 0.084
biosynthetic process GO:0009058 294 0.084
pronuclear migration GO:0035046 1 0.077
mitotic cell cycle process GO:1903047 48 0.076
positive regulation of biological process GO:0048518 253 0.075
neuron development GO:0048666 262 0.075
organ regeneration GO:0031100 1 0.074
rna metabolic process GO:0016070 219 0.072
cellular localization GO:0051641 97 0.071
single organism organelle organization GO:1902589 199 0.071
pore complex assembly GO:0046931 2 0.070
negative regulation of response to stimulus GO:0048585 104 0.069
response to abiotic stimulus GO:0009628 122 0.069
cell part morphogenesis GO:0032990 246 0.067
organic substance biosynthetic process GO:1901576 289 0.067
developmental growth GO:0048589 166 0.065
dna alkylation GO:0006305 8 0.063
eye photoreceptor cell differentiation GO:0001754 45 0.063
organism emergence from protective structure GO:0071684 4 0.062
heterocycle metabolic process GO:0046483 290 0.061
Human Yeast
macromolecule modification GO:0043412 111 0.060
spindle assembly involved in meiosis GO:0090306 1 0.060
positive regulation of cellular process GO:0048522 201 0.060
cellular response to stress GO:0033554 62 0.059
cellular response to organic substance GO:0071310 105 0.059
cell cycle GO:0007049 93 0.059
cellular response to external stimulus GO:0071496 2 0.059
protein complex localization GO:0031503 1 0.058
male meiosis GO:0007140 2 0.057
transport GO:0006810 220 0.056
positive regulation of biosynthetic process GO:0009891 68 0.056
tube morphogenesis GO:0035239 349 0.056
mitotic cell cycle GO:0000278 64 0.055
brain development GO:0007420 293 0.054
phosphorus metabolic process GO:0006793 109 0.053
positive regulation of gene expression GO:0010628 71 0.053
positive regulation of catabolic process GO:0009896 4 0.052
digestive tract development GO:0048565 265 0.052
lens development in camera type eye GO:0002088 22 0.052
chordate embryonic development GO:0043009 271 0.051
dna methylation on cytosine GO:0032776 3 0.050
cytoskeleton organization GO:0007010 96 0.050
peptidyl serine modification GO:0018209 2 0.049
regulation of histone h3 k9 methylation GO:0051570 2 0.049
chromosome segregation GO:0007059 12 0.048
cell projection organization GO:0030030 284 0.048
cellular nitrogen compound biosynthetic process GO:0044271 218 0.047
retina homeostasis GO:0001895 12 0.047
cell migration GO:0016477 237 0.046
regulation of mitotic cell cycle GO:0007346 25 0.046
retinal ganglion cell axon guidance GO:0031290 35 0.046
exocrine pancreas development GO:0031017 28 0.045
protein complex biogenesis GO:0070271 30 0.045
Human Yeast
chromosome organization involved in meiosis GO:0070192 1 0.045
morphogenesis of an epithelium GO:0002009 333 0.044
response to organic substance GO:0010033 153 0.044
exocrine system development GO:0035272 28 0.044
regulation of response to stimulus GO:0048583 269 0.043
cellular catabolic process GO:0044248 27 0.043
lipid homeostasis GO:0055088 3 0.043
neuron differentiation GO:0030182 353 0.042
mitotic cell cycle checkpoint GO:0007093 5 0.041
spindle assembly GO:0051225 2 0.041
regulation of meiotic cell cycle GO:0051445 1 0.041
growth GO:0040007 174 0.041
regulation of protein catabolic process GO:0042176 1 0.041
protein metabolic process GO:0019538 183 0.041
regeneration GO:0031099 91 0.040
recombinational repair GO:0000725 1 0.040
hatching GO:0035188 4 0.040
pancreas development GO:0031016 84 0.039
sister chromatid cohesion GO:0007062 2 0.039
peptidyl lysine dimethylation GO:0018027 1 0.039
single organism localization GO:1902578 225 0.038
establishment of localization GO:0051234 244 0.038
cellular component morphogenesis GO:0032989 336 0.038
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.038
cell surface receptor signaling pathway GO:0007166 325 0.037
microtubule based process GO:0007017 60 0.037
nuclear pore organization GO:0006999 2 0.037
organelle fission GO:0048285 23 0.037
negative regulation of histone methylation GO:0031061 1 0.037
positive regulation of dna metabolic process GO:0051054 1 0.036
regulation of cellular protein catabolic process GO:1903362 1 0.036
multi organism process GO:0051704 134 0.036
regulation of nucleic acid templated transcription GO:1903506 213 0.036
pharyngeal system development GO:0060037 18 0.036
photoreceptor cell differentiation GO:0046530 55 0.036
regulation of gene expression epigenetic GO:0040029 11 0.035
regulation of primary metabolic process GO:0080090 311 0.035
determination of heart left right asymmetry GO:0061371 117 0.035
regulation of cell cycle GO:0051726 52 0.035
multicellular organism growth GO:0035264 4 0.035
dna modification GO:0006304 8 0.035
g1 s transition of mitotic cell cycle GO:0000082 1 0.034
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.033
regulation of protein binding GO:0043393 3 0.032
cellular response to radiation GO:0071478 4 0.032
positive regulation of chromatin modification GO:1903310 1 0.032
cranial nerve development GO:0021545 42 0.032
nuclear migration GO:0007097 3 0.031
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.031
modification dependent protein catabolic process GO:0019941 3 0.030
cell morphogenesis GO:0000902 289 0.030
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.030
negative regulation of cell communication GO:0010648 96 0.029
negative regulation of chromosome organization GO:2001251 1 0.029
positive regulation of histone modification GO:0031058 1 0.029
determination of bilateral symmetry GO:0009855 204 0.028
positive regulation of transcription dna templated GO:0045893 57 0.028
cellular amine metabolic process GO:0044106 2 0.028
reproduction GO:0000003 40 0.028
Worm
regulation of rna metabolic process GO:0051252 224 0.028
specification of symmetry GO:0009799 204 0.028
amine metabolic process GO:0009308 2 0.027
eye photoreceptor cell development GO:0042462 30 0.027
phosphate containing compound metabolic process GO:0006796 108 0.027
positive regulation of rna biosynthetic process GO:1902680 57 0.026
regulation of histone methylation GO:0031060 3 0.026
cytokinesis GO:0000910 3 0.026
death GO:0016265 121 0.026
negative regulation of cell cycle phase transition GO:1901988 5 0.026
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.026
regulation of gene expression GO:0010468 265 0.026
peptidyl serine phosphorylation GO:0018105 1 0.026
regulation of cellular biosynthetic process GO:0031326 245 0.026
chromosome organization GO:0051276 31 0.026
Human Yeast
regulation of biosynthetic process GO:0009889 250 0.025
proteasomal protein catabolic process GO:0010498 2 0.025
response to ionizing radiation GO:0010212 6 0.025
modification dependent macromolecule catabolic process GO:0043632 3 0.024
organonitrogen compound metabolic process GO:1901564 74 0.024
cellular biosynthetic process GO:0044249 286 0.024
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.024
regulation of epithelial cell proliferation GO:0050678 3 0.023
carboxylic acid metabolic process GO:0019752 22 0.023
atp metabolic process GO:0046034 5 0.023
heart morphogenesis GO:0003007 156 0.023
regulation of neural precursor cell proliferation GO:2000177 3 0.023
regulation of protein complex assembly GO:0043254 3 0.023
regulation of cellular component organization GO:0051128 86 0.023
positive regulation of metabolic process GO:0009893 108 0.023
dna metabolic process GO:0006259 27 0.023
Human Yeast
cell cycle g1 s phase transition GO:0044843 1 0.022
autophagy GO:0006914 4 0.022
signal transduction GO:0007165 455 0.022
generation of neurons GO:0048699 385 0.022
protein localization to microtubule cytoskeleton GO:0072698 1 0.022
protein localization to centrosome GO:0071539 1 0.021
embryonic heart tube morphogenesis GO:0003143 108 0.021
regulation of cellular amine metabolic process GO:0033238 0 0.021
spindle assembly involved in female meiosis GO:0007056 1 0.021
multicellular organismal homeostasis GO:0048871 29 0.021
regulation of cell death GO:0010941 103 0.021
histone h3 k9 methylation GO:0051567 5 0.021
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.021
embryonic organ morphogenesis GO:0048562 274 0.021
histone methylation GO:0016571 13 0.021
response to stress GO:0006950 263 0.020
regulation of biological quality GO:0065008 263 0.020
organelle assembly GO:0070925 110 0.020
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.020
meiosis ii GO:0007135 1 0.020
positive regulation of cellular component biogenesis GO:0044089 3 0.020
positive regulation of secretion GO:0051047 1 0.020
mitotic sister chromatid cohesion GO:0007064 2 0.020
positive regulation of macromolecule metabolic process GO:0010604 93 0.020
establishment of nucleus localization GO:0040023 7 0.019
cellular response to oxygen levels GO:0071453 1 0.019
macromolecule localization GO:0033036 54 0.019
programmed cell death GO:0012501 119 0.019
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.019
response to drug GO:0042493 3 0.019
skeletal muscle organ development GO:0060538 78 0.019
establishment of protein localization to organelle GO:0072594 4 0.019
single organism metabolic process GO:0044710 217 0.019
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.018
peptidyl threonine phosphorylation GO:0018107 1 0.018
single fertilization GO:0007338 3 0.018
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000462 1 0.018
regulation of nitrogen compound metabolic process GO:0051171 251 0.018
histone h3 k4 methylation GO:0051568 2 0.018
nerve development GO:0021675 45 0.018
embryonic heart tube development GO:0035050 133 0.018
cellular response to oxygen containing compound GO:1901701 20 0.018
regulation of cellular ketone metabolic process GO:0010565 7 0.018
axon development GO:0061564 166 0.017
purine ribonucleotide metabolic process GO:0009150 27 0.017
organic acid metabolic process GO:0006082 31 0.017
regulation of binding GO:0051098 3 0.017
organic cyclic compound metabolic process GO:1901360 301 0.017
Human Yeast
cilium morphogenesis GO:0060271 85 0.017
purine nucleoside monophosphate metabolic process GO:0009126 5 0.017
negative regulation of biological process GO:0048519 304 0.017
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 2 0.017
small molecule metabolic process GO:0044281 77 0.017
epithelial cell morphogenesis GO:0003382 2 0.016
positive regulation of apoptotic signaling pathway GO:2001235 1 0.016
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.016
neuron projection development GO:0031175 180 0.016
response to external stimulus GO:0009605 264 0.016
cellular protein catabolic process GO:0044257 4 0.016
protein complex subunit organization GO:0071822 46 0.016
Human Yeast
protein alkylation GO:0008213 13 0.016
positive regulation of nucleotide catabolic process GO:0030813 1 0.016
catabolic process GO:0009056 32 0.016
regulation of dna methylation GO:0044030 5 0.016
sister chromatid segregation GO:0000819 6 0.015
transmission of nerve impulse GO:0019226 19 0.015
embryonic organ development GO:0048568 381 0.015
dorsal ventral pattern formation GO:0009953 125 0.015
negative regulation of smoothened signaling pathway GO:0045879 6 0.015
apoptotic process GO:0006915 116 0.015
response to endogenous stimulus GO:0009719 83 0.015
positive regulation of chromosome organization GO:2001252 1 0.015
dna damage checkpoint GO:0000077 6 0.015
nucleocytoplasmic transport GO:0006913 4 0.015
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.015
dna methylation GO:0006306 8 0.015
dna biosynthetic process GO:0071897 3 0.014
response to organic cyclic compound GO:0014070 51 0.014
cellular amino acid metabolic process GO:0006520 7 0.014
system process GO:0003008 185 0.014
cell substrate adhesion GO:0031589 4 0.014
vesicle mediated transport GO:0016192 22 0.014
meiotic cell cycle GO:0051321 5 0.014
axonogenesis GO:0007409 152 0.014
cell cycle phase transition GO:0044770 9 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.014
negative regulation of rna metabolic process GO:0051253 48 0.014
regulation of reproductive process GO:2000241 4 0.014
nuclear transport GO:0051169 4 0.014
anatomical structure homeostasis GO:0060249 36 0.014
wound healing GO:0042060 90 0.014
regulation of peptidase activity GO:0052547 23 0.014
histone lysine methylation GO:0034968 12 0.014
cellular ketone metabolic process GO:0042180 11 0.014
response to organonitrogen compound GO:0010243 12 0.014
positive regulation of cellular amine metabolic process GO:0033240 0 0.014
regulation of programmed cell death GO:0043067 101 0.014
cellular response to hypoxia GO:0071456 1 0.013
cellular carbohydrate metabolic process GO:0044262 4 0.013
response to wounding GO:0009611 116 0.013
nuclear import GO:0051170 3 0.013
blood circulation GO:0008015 87 0.013
regulation of nervous system development GO:0051960 90 0.013
meiotic spindle organization GO:0000212 1 0.013
homeostasis of number of cells within a tissue GO:0048873 4 0.013
posttranscriptional gene silencing GO:0016441 3 0.013
regionalization GO:0003002 274 0.013
heart looping GO:0001947 94 0.013
central nervous system development GO:0007417 387 0.013
regulation of localization GO:0032879 104 0.013
cellular protein modification process GO:0006464 100 0.013
female meiotic division GO:0007143 2 0.013
protein methylation GO:0006479 13 0.012
single organism transport GO:0044765 206 0.012
spindle assembly involved in mitosis GO:0090307 1 0.012
positive regulation of cell cycle GO:0045787 3 0.012
tube closure GO:0060606 1 0.012
positive regulation of cyclin dependent protein serine threonine kinase activity GO:0045737 1 0.012
tissue remodeling GO:0048771 4 0.012
positive regulation of cellular biosynthetic process GO:0031328 68 0.012
multi organism reproductive process GO:0044703 36 0.012
negative regulation of nuclear division GO:0051784 3 0.012
heart development GO:0007507 313 0.012
positive regulation of nucleic acid templated transcription GO:1903508 57 0.012
cellular aromatic compound metabolic process GO:0006725 295 0.012
Human Yeast
cell cycle checkpoint GO:0000075 7 0.012
guanosine containing compound catabolic process GO:1901069 2 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.012
organophosphate metabolic process GO:0019637 37 0.012
protein acylation GO:0043543 3 0.012
multi organism cellular process GO:0044764 2 0.012
regulation of apoptotic process GO:0042981 98 0.012
epithelial tube morphogenesis GO:0060562 148 0.011
dna methylation or demethylation GO:0044728 8 0.011
aging GO:0007568 2 0.011
cellular protein complex localization GO:0034629 1 0.011
regulation of transcription dna templated GO:0006355 213 0.011
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.011
gene expression GO:0010467 252 0.011
cell death GO:0008219 121 0.011
regulation of macromolecule biosynthetic process GO:0010556 225 0.011
negative regulation of catabolic process GO:0009895 3 0.011
maintenance of location GO:0051235 4 0.011
oxoacid metabolic process GO:0043436 31 0.011
negative regulation of dna metabolic process GO:0051053 4 0.011
positive regulation of response to stimulus GO:0048584 80 0.011
negative regulation of macromolecule metabolic process GO:0010605 76 0.011
regulation of organelle assembly GO:1902115 4 0.011
regulation of dna metabolic process GO:0051052 11 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.011
histone deacetylation GO:0016575 2 0.011
regulation of cell proliferation GO:0042127 37 0.011
nucleobase containing small molecule metabolic process GO:0055086 32 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.011
response to light stimulus GO:0009416 46 0.011
telomere organization GO:0032200 1 0.011
protein modification process GO:0036211 100 0.011
fertilization GO:0009566 3 0.011
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 0 0.011
transcription from rna polymerase ii promoter GO:0006366 80 0.011
phosphorylation GO:0016310 69 0.011
tissue homeostasis GO:0001894 25 0.011
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.011
negative regulation of dna replication GO:0008156 2 0.011
actomyosin structure organization GO:0031032 53 0.011
organic substance catabolic process GO:1901575 28 0.011
chemotaxis GO:0006935 104 0.011
macromolecule methylation GO:0043414 19 0.010
homeostatic process GO:0042592 142 0.010
b cell differentiation GO:0030183 1 0.010
axon guidance GO:0007411 86 0.010
negative regulation of meiotic cell cycle GO:0051447 1 0.010
interspecies interaction between organisms GO:0044419 4 0.010
smoothened signaling pathway GO:0007224 30 0.010
regulation of cell cycle process GO:0010564 20 0.010
organic cyclic compound catabolic process GO:1901361 15 0.010
proteolysis GO:0006508 38 0.010
ribonucleoside monophosphate metabolic process GO:0009161 5 0.010
synapsis GO:0007129 1 0.010
macromolecular complex assembly GO:0065003 35 0.010
Human Yeast
regulation of proteolysis GO:0030162 24 0.010
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.010
regulation of molecular function GO:0065009 70 0.010

chaf1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
physical disorder DOID:0080015 0 0.032
congenital nervous system abnormality DOID:2490 0 0.032
thoracic cancer DOID:5093 0 0.030
cancer DOID:162 0 0.030
disease of cellular proliferation DOID:14566 0 0.030
organ system cancer DOID:0050686 0 0.030
large intestine cancer DOID:5672 0 0.015
gastrointestinal system cancer DOID:3119 0 0.015
intestinal cancer DOID:10155 0 0.015
colorectal cancer DOID:9256 0 0.013