Danio rerio

0 known processes

pfdn2

prefoldin subunit 2

(Aliases: zgc:136473,wu:fb79a01,im:6895552)

pfdn2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.388
Worm
single organism transport GO:0044765 206 0.189
Fly
single organism localization GO:1902578 225 0.150
Fly
response to stress GO:0006950 263 0.109
nitrogen compound metabolic process GO:0006807 319 0.106
cellular macromolecule metabolic process GO:0044260 391 0.105
multicellular organism growth GO:0035264 4 0.089
regulation of metabolic process GO:0019222 359 0.086
cellular protein catabolic process GO:0044257 4 0.082
proteasomal protein catabolic process GO:0010498 2 0.078
regulation of gene expression GO:0010468 265 0.073
cell motility GO:0048870 244 0.072
aging GO:0007568 2 0.071
locomotion GO:0040011 313 0.069
Worm
cellular nitrogen compound metabolic process GO:0034641 290 0.066
multi organism process GO:0051704 134 0.064
Worm Fly
nucleic acid metabolic process GO:0090304 244 0.064
single fertilization GO:0007338 3 0.063
Worm
sexual reproduction GO:0019953 36 0.060
Worm Fly
establishment of localization GO:0051234 244 0.059
Worm Fly
gene expression GO:0010467 252 0.058
rna biosynthetic process GO:0032774 181 0.057
nucleobase containing compound metabolic process GO:0006139 274 0.056
organic cyclic compound metabolic process GO:1901360 301 0.056
fertilization GO:0009566 3 0.052
Worm
mitochondrion organization GO:0007005 4 0.051
cellular component biogenesis GO:0044085 178 0.051
generation of neurons GO:0048699 385 0.051
meiotic cell cycle process GO:1903046 3 0.050
cellular response to extracellular stimulus GO:0031668 2 0.050
transport GO:0006810 220 0.049
Fly
regulation of multicellular organism growth GO:0040014 4 0.048
regulation of biosynthetic process GO:0009889 250 0.048
meiotic chromosome segregation GO:0045132 3 0.048
phagocytosis GO:0006909 3 0.047
Fly
embryo development ending in birth or egg hatching GO:0009792 271 0.047
Worm
nucleus organization GO:0006997 7 0.047
response to abiotic stimulus GO:0009628 122 0.046
negative regulation of signaling GO:0023057 96 0.045
nucleobase containing compound biosynthetic process GO:0034654 205 0.044
embryonic organ development GO:0048568 381 0.044
rna metabolic process GO:0016070 219 0.044
cellular component assembly GO:0022607 170 0.044
localization of cell GO:0051674 244 0.043
regulation of developmental process GO:0050793 247 0.042
tube morphogenesis GO:0035239 349 0.042
response to carbohydrate GO:0009743 3 0.042
cellular component disassembly GO:0022411 1 0.042
positive regulation of biological process GO:0048518 253 0.041
negative regulation of developmental process GO:0051093 65 0.039
heterocycle metabolic process GO:0046483 290 0.039
regulation of macromolecule metabolic process GO:0060255 317 0.039
regulation of cellular biosynthetic process GO:0031326 245 0.039
single organism metabolic process GO:0044710 217 0.039
autophagy GO:0006914 4 0.035
response to drug GO:0042493 3 0.034
regulation of establishment of protein localization GO:0070201 4 0.034
small molecule metabolic process GO:0044281 77 0.033
cellular response to external stimulus GO:0071496 2 0.033
positive regulation of cellular catabolic process GO:0031331 3 0.032
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.032
nucleic acid templated transcription GO:0097659 181 0.032
regulation of macromolecule biosynthetic process GO:0010556 225 0.032
single organism organelle organization GO:1902589 199 0.031
cell migration GO:0016477 237 0.031
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.030
cellular amine metabolic process GO:0044106 2 0.030
regulation of rna biosynthetic process GO:2001141 213 0.030
modification dependent protein catabolic process GO:0019941 3 0.029
cellular aromatic compound metabolic process GO:0006725 295 0.029
cellular ketone metabolic process GO:0042180 11 0.028
programmed cell death GO:0012501 119 0.028
organic cyclic compound biosynthetic process GO:1901362 223 0.028
regulation of cellular amino acid metabolic process GO:0006521 0 0.027
response to chemical GO:0042221 320 0.027
organic acid metabolic process GO:0006082 31 0.027
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.026
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.026
nuclear transport GO:0051169 4 0.026
protein acetylation GO:0006473 2 0.026
negative regulation of cell death GO:0060548 60 0.026
negative regulation of cell communication GO:0010648 96 0.026
negative regulation of signal transduction by p53 class mediator GO:1901797 8 0.025
cellular macromolecule biosynthetic process GO:0034645 224 0.025
negative regulation of response to stimulus GO:0048585 104 0.025
cell part morphogenesis GO:0032990 246 0.025
regulation of cytoplasmic transport GO:1903649 4 0.025
internal peptidyl lysine acetylation GO:0018393 2 0.025
amine metabolic process GO:0009308 2 0.025
cellular amino acid metabolic process GO:0006520 7 0.025
establishment of protein localization to organelle GO:0072594 4 0.025
regulation of cellular amine metabolic process GO:0033238 0 0.024
regulation of cellular ketone metabolic process GO:0010565 7 0.024
negative regulation of signal transduction GO:0009968 94 0.024
negative regulation of multicellular organismal process GO:0051241 69 0.024
organelle assembly GO:0070925 110 0.024
ubiquitin dependent protein catabolic process GO:0006511 3 0.023
synaptic vesicle transport GO:0048489 1 0.023
positive regulation of cellular component biogenesis GO:0044089 3 0.023
regulation of nitrogen compound metabolic process GO:0051171 251 0.023
determination of bilateral symmetry GO:0009855 204 0.023
regulation of rna metabolic process GO:0051252 224 0.023
neuron differentiation GO:0030182 353 0.023
protein targeting to nucleus GO:0044744 3 0.023
spindle assembly GO:0051225 2 0.023
response to monosaccharide GO:0034284 3 0.022
stem cell proliferation GO:0072089 4 0.021
regulation of transcription dna templated GO:0006355 213 0.021
regulation of signal transduction GO:0009966 225 0.021
positive regulation of transport GO:0051050 2 0.021
heart development GO:0007507 313 0.020
protein secretion GO:0009306 1 0.020
aromatic compound biosynthetic process GO:0019438 217 0.020
regulation of multicellular organismal process GO:0051239 277 0.020
gtp catabolic process GO:0006184 2 0.020
apoptotic process GO:0006915 116 0.020
positive regulation of biosynthetic process GO:0009891 68 0.020
carboxylic acid metabolic process GO:0019752 22 0.020
stem cell maintenance GO:0019827 4 0.020
internal protein amino acid acetylation GO:0006475 2 0.020
regulation of nucleic acid templated transcription GO:1903506 213 0.020
positive regulation of cellular biosynthetic process GO:0031328 68 0.020
mesoderm development GO:0007498 88 0.019
gtp metabolic process GO:0046039 4 0.019
heterocycle biosynthetic process GO:0018130 215 0.019
response to glucose GO:0009749 3 0.019
modification dependent macromolecule catabolic process GO:0043632 3 0.019
regulation of synapse organization GO:0050807 3 0.019
negative regulation of biological process GO:0048519 304 0.019
regulation of multicellular organismal development GO:2000026 223 0.019
positive regulation of cellular metabolic process GO:0031325 94 0.019
lateral inhibition GO:0046331 1 0.019
organonitrogen compound metabolic process GO:1901564 74 0.019
regulation of cell development GO:0060284 100 0.019
organelle organization GO:0006996 227 0.019
macromolecular complex disassembly GO:0032984 1 0.018
cellular component movement GO:0006928 335 0.018
cellular response to nutrient levels GO:0031669 2 0.018
meiotic nuclear division GO:0007126 4 0.018
transcription dna templated GO:0006351 181 0.018
negative regulation of macromolecule metabolic process GO:0010605 76 0.018
protein import into nucleus GO:0006606 3 0.018
carbohydrate biosynthetic process GO:0016051 1 0.018
reproductive process GO:0022414 40 0.018
Worm Fly
oxoacid metabolic process GO:0043436 31 0.018
positive regulation of gene expression GO:0010628 71 0.018
biosynthetic process GO:0009058 294 0.018
digestive tract development GO:0048565 265 0.017
protein complex assembly GO:0006461 30 0.017
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.017
mitotic dna integrity checkpoint GO:0044774 4 0.017
regulation of protein catabolic process GO:0042176 1 0.017
cell morphogenesis GO:0000902 289 0.017
neuroblast proliferation GO:0007405 2 0.017
nuclear import GO:0051170 3 0.017
brain development GO:0007420 293 0.017
macromolecular complex assembly GO:0065003 35 0.017
regulation of biological quality GO:0065008 263 0.017
cellular response to stress GO:0033554 62 0.017
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.017
mesenchyme development GO:0060485 127 0.016
regulation of programmed cell death GO:0043067 101 0.016
regulation of response to stimulus GO:0048583 269 0.016
response to hexose GO:0009746 3 0.016
response to wounding GO:0009611 116 0.016
negative regulation of cellular process GO:0048523 283 0.016
establishment of localization in cell GO:0051649 77 0.016
Worm
nucleocytoplasmic transport GO:0006913 4 0.016
signal transduction GO:0007165 455 0.016
anterior posterior pattern specification GO:0009952 152 0.016
regulation of synaptic plasticity GO:0048167 1 0.016
regulation of anatomical structure morphogenesis GO:0022603 130 0.016
developmental growth GO:0048589 166 0.016
regulation of protein transport GO:0051223 3 0.016
positive regulation of rna metabolic process GO:0051254 59 0.016
regulation of cell death GO:0010941 103 0.015
cellular response to chemical stimulus GO:0070887 157 0.015
regulation of nucleoside metabolic process GO:0009118 2 0.015
peptidyl lysine acetylation GO:0018394 2 0.015
neuron projection development GO:0031175 180 0.015
spermatid differentiation GO:0048515 2 0.015
determination of heart left right asymmetry GO:0061371 117 0.015
positive regulation of transcription dna templated GO:0045893 57 0.015
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.015
reproduction GO:0000003 40 0.015
Worm Fly
protein localization to nucleus GO:0034504 3 0.015
spermatid development GO:0007286 2 0.015
protein polymerization GO:0051258 4 0.015
growth GO:0040007 174 0.015
cell death GO:0008219 121 0.014
regulation of intracellular protein transport GO:0033157 3 0.014
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.014
transcription from rna polymerase ii promoter GO:0006366 80 0.014
stem cell division GO:0017145 1 0.014
protein metabolic process GO:0019538 183 0.014
centrosome organization GO:0051297 1 0.014
positive regulation of catabolic process GO:0009896 4 0.014
protein import GO:0017038 3 0.014
positive regulation of cellular process GO:0048522 201 0.014
negative regulation of programmed cell death GO:0043069 58 0.014
regulation of neuron differentiation GO:0045664 56 0.014
cellular carbohydrate metabolic process GO:0044262 4 0.014
adult behavior GO:0030534 2 0.013
mitotic dna damage checkpoint GO:0044773 4 0.013
organism emergence from protective structure GO:0071684 4 0.013
positive regulation of cell cycle GO:0045787 3 0.013
guanosine containing compound catabolic process GO:1901069 2 0.013
oocyte anterior posterior axis specification GO:0007314 4 0.013
microtubule organizing center organization GO:0031023 1 0.013
developmental programmed cell death GO:0010623 4 0.013
response to external stimulus GO:0009605 264 0.013
cell projection morphogenesis GO:0048858 244 0.013
extrinsic apoptotic signaling pathway GO:0097191 3 0.013
carbohydrate homeostasis GO:0033500 1 0.013
protein acylation GO:0043543 3 0.013
mechanosensory behavior GO:0007638 2 0.013
gabaergic neuron differentiation GO:0097154 2 0.013
positive regulation of cellular amine metabolic process GO:0033240 0 0.013
embryonic limb morphogenesis GO:0030326 2 0.013
central nervous system development GO:0007417 387 0.013
protein complex subunit organization GO:0071822 46 0.013
regulation of cell differentiation GO:0045595 142 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.013
regulation of stem cell differentiation GO:2000736 4 0.013
somitogenesis GO:0001756 87 0.013
synaptic vesicle localization GO:0097479 1 0.012
regulation of carbohydrate metabolic process GO:0006109 4 0.012
neuron development GO:0048666 262 0.012
protein k63 linked ubiquitination GO:0070534 2 0.012
negative regulation of neuron projection regeneration GO:0070571 4 0.012
mitotic cell cycle process GO:1903047 48 0.012
regulation of inflammatory response GO:0050727 2 0.012
cilium morphogenesis GO:0060271 85 0.012
positive regulation of gliogenesis GO:0014015 2 0.012
cellular protein metabolic process GO:0044267 129 0.012
organic substance biosynthetic process GO:1901576 289 0.012
angiogenesis GO:0001525 158 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.012
tissue remodeling GO:0048771 4 0.012
regulation of signaling GO:0023051 235 0.012
single organism nuclear import GO:1902593 3 0.012
death GO:0016265 121 0.012
regulation of cellular metabolic process GO:0031323 320 0.012
cellular nitrogen compound biosynthetic process GO:0044271 218 0.012
multicellular organismal reproductive process GO:0048609 35 0.012
Fly
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.012
positive regulation of nucleic acid templated transcription GO:1903508 57 0.012
centrosome duplication GO:0051298 1 0.011
membrane invagination GO:0010324 1 0.011
embryonic digestive tract morphogenesis GO:0048557 3 0.011
post embryonic morphogenesis GO:0009886 4 0.011
mitotic g2 dna damage checkpoint GO:0007095 3 0.011
regulation of dna damage response signal transduction by p53 class mediator GO:0043516 4 0.011
regulation of cell activation GO:0050865 1 0.011
nucleic acid phosphodiester bond hydrolysis GO:0090305 6 0.011
cellular response to starvation GO:0009267 1 0.011
negative regulation of apoptotic process GO:0043066 55 0.011
dna catabolic process GO:0006308 1 0.011
determination of left right symmetry GO:0007368 179 0.011
organic substance transport GO:0071702 58 0.011
regulation of gtp catabolic process GO:0033124 2 0.011
somite development GO:0061053 96 0.011
cell surface receptor signaling pathway GO:0007166 325 0.011
specification of symmetry GO:0009799 204 0.011
regionalization GO:0003002 274 0.011
macroautophagy GO:0016236 1 0.011
positive regulation of nucleotide catabolic process GO:0030813 1 0.011
protein complex biogenesis GO:0070271 30 0.011
regulation of synapse assembly GO:0051963 3 0.011
regulation of nucleocytoplasmic transport GO:0046822 2 0.011
positive regulation of dna metabolic process GO:0051054 1 0.011
regulation of cell shape GO:0008360 1 0.011
protein stabilization GO:0050821 2 0.010
pole plasm assembly GO:0007315 4 0.010
macromolecule biosynthetic process GO:0009059 227 0.010
regulation of neural precursor cell proliferation GO:2000177 3 0.010
regulation of apoptotic process GO:0042981 98 0.010
phagocytosis engulfment GO:0006911 1 0.010
embryonic digestive tract development GO:0048566 4 0.010
macromolecule modification GO:0043412 111 0.010
cilium organization GO:0044782 71 0.010
regulation of purine nucleotide catabolic process GO:0033121 2 0.010

pfdn2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.031
cancer DOID:162 0 0.023
disease of cellular proliferation DOID:14566 0 0.023
organ system cancer DOID:0050686 0 0.023
nervous system disease DOID:863 0 0.021