Danio rerio

44 known processes

dixdc1a

DIX domain containing 1a

(Aliases: ccd1,dixdc1)

dixdc1a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
central nervous system development GO:0007417 387 0.219
signal transduction GO:0007165 455 0.212
embryonic organ development GO:0048568 381 0.166
embryonic organ morphogenesis GO:0048562 274 0.139
cellular component movement GO:0006928 335 0.126
head development GO:0060322 303 0.111
organic substance biosynthetic process GO:1901576 289 0.107
larval development GO:0002164 2 0.105
locomotion GO:0040011 313 0.102
chordate embryonic development GO:0043009 271 0.091
positive regulation of cellular process GO:0048522 201 0.088
stem cell differentiation GO:0048863 117 0.082
ameboidal type cell migration GO:0001667 143 0.078
skeletal system development GO:0001501 181 0.076
embryonic skeletal system development GO:0048706 97 0.074
tube closure GO:0060606 1 0.074
negative regulation of intracellular protein transport GO:0090317 3 0.072
negative regulation of protein transport GO:0051224 3 0.067
regulation of nitrogen compound metabolic process GO:0051171 251 0.064
neuron differentiation GO:0030182 353 0.064
cell morphogenesis involved in differentiation GO:0000904 195 0.064
nuclear migration GO:0007097 3 0.063
regulation of cellular metabolic process GO:0031323 320 0.062
guanosine containing compound catabolic process GO:1901069 2 0.061
biosynthetic process GO:0009058 294 0.060
embryo development ending in birth or egg hatching GO:0009792 271 0.058
cellular macromolecule metabolic process GO:0044260 391 0.058
anterior posterior pattern specification GO:0009952 152 0.058
guanosine containing compound metabolic process GO:1901068 4 0.057
nucleic acid metabolic process GO:0090304 244 0.056
cellular nitrogen compound metabolic process GO:0034641 290 0.055
cellular biosynthetic process GO:0044249 286 0.054
response to organic substance GO:0010033 153 0.053
regulation of intracellular protein transport GO:0033157 3 0.053
macromolecule biosynthetic process GO:0009059 227 0.052
response to stress GO:0006950 263 0.052
cellular nitrogen compound biosynthetic process GO:0044271 218 0.051
primary neural tube formation GO:0014020 1 0.050
heterocycle biosynthetic process GO:0018130 215 0.049
regulation of protein transport GO:0051223 3 0.049
regulation of signal transduction GO:0009966 225 0.048
regulation of establishment of protein localization GO:0070201 4 0.048
regulation of multicellular organismal process GO:0051239 277 0.048
organic cyclic compound biosynthetic process GO:1901362 223 0.048
regulation of signaling GO:0023051 235 0.047
regulation of nucleoside metabolic process GO:0009118 2 0.047
cellular component morphogenesis GO:0032989 336 0.046
regulation of primary metabolic process GO:0080090 311 0.046
single organism transport GO:0044765 206 0.046
digestive tract morphogenesis GO:0048546 231 0.045
regulation of nucleic acid templated transcription GO:1903506 213 0.045
neuron projection development GO:0031175 180 0.044
sympathetic nervous system development GO:0048485 3 0.044
aromatic compound biosynthetic process GO:0019438 217 0.044
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.044
cell projection morphogenesis GO:0048858 244 0.043
regulation of multicellular organism growth GO:0040014 4 0.043
cell projection organization GO:0030030 284 0.043
regulation of cell activation GO:0050865 1 0.042
cellular macromolecule biosynthetic process GO:0034645 224 0.042
regulation of purine nucleotide catabolic process GO:0033121 2 0.042
cell part morphogenesis GO:0032990 246 0.042
regulation of cellular amino acid metabolic process GO:0006521 0 0.042
protein import GO:0017038 3 0.042
regulation of rna metabolic process GO:0051252 224 0.041
mononuclear cell proliferation GO:0032943 1 0.040
rna biosynthetic process GO:0032774 181 0.040
positive regulation of secretion by cell GO:1903532 1 0.040
regulation of biosynthetic process GO:0009889 250 0.039
positive regulation of biological process GO:0048518 253 0.039
transport GO:0006810 220 0.039
amine metabolic process GO:0009308 2 0.039
localization of cell GO:0051674 244 0.039
embryonic skeletal system morphogenesis GO:0048704 93 0.039
transcription dna templated GO:0006351 181 0.039
regulation of gtp catabolic process GO:0033124 2 0.039
nitrogen compound metabolic process GO:0006807 319 0.039
extrinsic apoptotic signaling pathway GO:0097191 3 0.039
cell motility GO:0048870 244 0.039
regulation of developmental process GO:0050793 247 0.039
regulation of transcription dna templated GO:0006355 213 0.038
central nervous system neuron differentiation GO:0021953 74 0.038
regulation of cytokine production GO:0001817 3 0.038
cell migration GO:0016477 237 0.037
morphogenesis of an epithelium GO:0002009 333 0.037
hormone transport GO:0009914 2 0.037
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.036
heterocycle metabolic process GO:0046483 290 0.036
gtp metabolic process GO:0046039 4 0.036
regulation of hormone secretion GO:0046883 2 0.036
regulation of protein complex assembly GO:0043254 3 0.036
brain development GO:0007420 293 0.036
immune system process GO:0002376 241 0.036
aging GO:0007568 2 0.035
axon development GO:0061564 166 0.035
negative regulation of biological process GO:0048519 304 0.035
cell morphogenesis GO:0000902 289 0.035
regulation of biological quality GO:0065008 263 0.034
gtp catabolic process GO:0006184 2 0.033
regulation of metabolic process GO:0019222 359 0.033
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.033
tube morphogenesis GO:0035239 349 0.033
positive regulation of gene expression GO:0010628 71 0.032
positive regulation of gtp catabolic process GO:0033126 1 0.032
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.032
regulation of cellular biosynthetic process GO:0031326 245 0.032
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.031
regulation of macromolecule biosynthetic process GO:0010556 225 0.031
negative regulation of secretion by cell GO:1903531 2 0.031
liver development GO:0001889 96 0.031
phagocytosis GO:0006909 3 0.031
blood vessel development GO:0001568 246 0.031
cell surface receptor signaling pathway GO:0007166 325 0.031
response to wounding GO:0009611 116 0.031
nucleus localization GO:0051647 8 0.031
cellular response to organic substance GO:0071310 105 0.030
nuclear transport GO:0051169 4 0.030
regulation of protein targeting GO:1903533 2 0.030
skeletal system morphogenesis GO:0048705 102 0.030
positive regulation of transport GO:0051050 2 0.030
actin filament based process GO:0030029 64 0.030
outflow tract morphogenesis GO:0003151 1 0.030
regulation of cell differentiation GO:0045595 142 0.030
regulation of neurogenesis GO:0050767 87 0.029
programmed cell death GO:0012501 119 0.029
regulation of cellular ketone metabolic process GO:0010565 7 0.029
negative regulation of cell differentiation GO:0045596 46 0.028
response to glucose GO:0009749 3 0.028
angiogenesis GO:0001525 158 0.028
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.028
cellular ketone metabolic process GO:0042180 11 0.028
single organism organelle organization GO:1902589 199 0.028
inner ear development GO:0048839 126 0.028
regulation of multicellular organismal development GO:2000026 223 0.028
forebrain regionalization GO:0021871 4 0.028
mesoderm development GO:0007498 88 0.028
wound healing GO:0042060 90 0.027
cell matrix adhesion GO:0007160 4 0.027
establishment of localization GO:0051234 244 0.027
positive regulation of secretion GO:0051047 1 0.027
regulation of protein ubiquitination GO:0031396 3 0.027
lamellipodium assembly GO:0030032 1 0.026
response to nutrient GO:0007584 3 0.026
fatty acid transport GO:0015908 1 0.026
maintenance of location GO:0051235 4 0.026
rna metabolic process GO:0016070 219 0.026
system process GO:0003008 185 0.026
nucleobase containing compound metabolic process GO:0006139 274 0.025
stem cell proliferation GO:0072089 4 0.025
stem cell maintenance GO:0019827 4 0.025
blood vessel morphogenesis GO:0048514 216 0.025
regulation of epithelial cell proliferation GO:0050678 3 0.025
intracellular signal transduction GO:0035556 85 0.025
mesenchymal cell development GO:0014031 78 0.025
multicellular organism growth GO:0035264 4 0.025
exocrine pancreas development GO:0031017 28 0.025
positive regulation of cell substrate adhesion GO:0010811 1 0.025
positive regulation of nucleoside metabolic process GO:0045979 1 0.025
negative regulation of chemotaxis GO:0050922 4 0.025
establishment of localization in cell GO:0051649 77 0.025
negative regulation of intracellular transport GO:0032387 3 0.025
lymphocyte proliferation GO:0046651 1 0.024
carbohydrate homeostasis GO:0033500 1 0.024
nucleobase containing compound biosynthetic process GO:0034654 205 0.024
epithelial cell differentiation GO:0030855 116 0.024
positive regulation of cellular catabolic process GO:0031331 3 0.024
homeostatic process GO:0042592 142 0.024
cellular response to chemical stimulus GO:0070887 157 0.024
digestive system development GO:0055123 289 0.024
single organism metabolic process GO:0044710 217 0.024
organic cyclic compound metabolic process GO:1901360 301 0.024
regulation of cellular amine metabolic process GO:0033238 0 0.023
nucleic acid templated transcription GO:0097659 181 0.023
nucleocytoplasmic transport GO:0006913 4 0.023
positive regulation of cell adhesion GO:0045785 1 0.023
transcription from rna polymerase ii promoter GO:0006366 80 0.023
cytoskeleton organization GO:0007010 96 0.023
positive regulation of cytokine production GO:0001819 2 0.023
regulation of rna biosynthetic process GO:2001141 213 0.023
phosphate containing compound metabolic process GO:0006796 108 0.023
positive regulation of rna metabolic process GO:0051254 59 0.023
negative regulation of cell communication GO:0010648 96 0.023
cell migration involved in gastrulation GO:0042074 79 0.023
regulation of cell projection assembly GO:0060491 4 0.023
cell cycle g1 s phase transition GO:0044843 1 0.023
regulation of cellular component movement GO:0051270 55 0.023
protein acetylation GO:0006473 2 0.022
cell substrate adhesion GO:0031589 4 0.022
establishment of nucleus localization GO:0040023 7 0.022
positive regulation of cellular metabolic process GO:0031325 94 0.022
cellular amine metabolic process GO:0044106 2 0.022
positive regulation of catabolic process GO:0009896 4 0.022
organonitrogen compound metabolic process GO:1901564 74 0.022
leukocyte proliferation GO:0070661 1 0.022
epithelial tube morphogenesis GO:0060562 148 0.022
negative regulation of cytoplasmic transport GO:1903650 2 0.022
forebrain cell migration GO:0021885 1 0.022
regulation of cytoplasmic transport GO:1903649 4 0.022
negative regulation of secretion GO:0051048 2 0.022
peptide transport GO:0015833 1 0.021
regulation of cell shape GO:0008360 1 0.021
digestive tract development GO:0048565 265 0.021
embryonic heart tube development GO:0035050 133 0.021
response to chemical GO:0042221 320 0.021
taxis GO:0042330 109 0.021
sensory organ development GO:0007423 393 0.021
regulation of cell substrate adhesion GO:0010810 1 0.020
regulation of autophagy GO:0010506 3 0.020
protein acylation GO:0043543 3 0.020
protein localization to nucleus GO:0034504 3 0.020
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.020
response to carbohydrate GO:0009743 3 0.020
purine nucleotide metabolic process GO:0006163 27 0.020
pectoral fin morphogenesis GO:0035138 29 0.019
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.019
cardiac cell fate commitment GO:0060911 1 0.019
regulation of localization GO:0032879 104 0.019
regulation of anatomical structure morphogenesis GO:0022603 130 0.019
positive regulation of gtpase activity GO:0043547 1 0.019
developmental growth GO:0048589 166 0.019
mesenchyme development GO:0060485 127 0.019
pronuclear migration GO:0035046 1 0.019
axonogenesis GO:0007409 152 0.019
protein targeting to nucleus GO:0044744 3 0.019
regeneration GO:0031099 91 0.019
positive regulation of multicellular organismal process GO:0051240 52 0.018
positive regulation of cellular amine metabolic process GO:0033240 0 0.018
gland development GO:0048732 143 0.018
lamellipodium organization GO:0097581 1 0.018
neuroblast proliferation GO:0007405 2 0.018
neurological system process GO:0050877 62 0.018
generation of neurons GO:0048699 385 0.018
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.018
cell fate commitment GO:0045165 99 0.018
convergent extension GO:0060026 118 0.018
regionalization GO:0003002 274 0.018
astrocyte differentiation GO:0048708 1 0.018
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.018
cellular carbohydrate metabolic process GO:0044262 4 0.018
regulation of stem cell proliferation GO:0072091 2 0.018
regulation of macromolecule metabolic process GO:0060255 317 0.018
negative regulation of dna metabolic process GO:0051053 4 0.017
protein metabolic process GO:0019538 183 0.017
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.017
negative regulation of axon guidance GO:1902668 1 0.017
embryonic cranial skeleton morphogenesis GO:0048701 90 0.017
positive regulation of cell cycle GO:0045787 3 0.017
cellular amino acid metabolic process GO:0006520 7 0.017
hepaticobiliary system development GO:0061008 98 0.017
dorsal ventral pattern formation GO:0009953 125 0.017
single organism localization GO:1902578 225 0.017
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.017
response to monosaccharide GO:0034284 3 0.016
mechanosensory lateral line system development GO:0048881 49 0.016
cell fate specification GO:0001708 68 0.016
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.016
cellular response to hormone stimulus GO:0032870 39 0.016
regulation of nucleocytoplasmic transport GO:0046822 2 0.016
vasculature development GO:0001944 278 0.016
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.016
olfactory bulb development GO:0021772 4 0.016
protein secretion GO:0009306 1 0.016
gastrulation GO:0007369 208 0.016
cellular protein metabolic process GO:0044267 129 0.016
negative regulation of response to stimulus GO:0048585 104 0.016
cellular response to external stimulus GO:0071496 2 0.016
central nervous system myelination GO:0022010 2 0.016
hatching GO:0035188 4 0.015
hindbrain development GO:0030902 91 0.015
apoptotic process GO:0006915 116 0.015
regulation of establishment of planar polarity GO:0090175 4 0.015
chemosensory behavior GO:0007635 1 0.015
ribonucleoside monophosphate catabolic process GO:0009158 4 0.015
synaptic target recognition GO:0008039 1 0.015
neuron development GO:0048666 262 0.015
nuclear import GO:0051170 3 0.015
autophagy GO:0006914 4 0.015
positive regulation of cell death GO:0010942 29 0.015
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.015
mechanosensory behavior GO:0007638 2 0.015
positive regulation of cellular component biogenesis GO:0044089 3 0.015
macroautophagy GO:0016236 1 0.015
tube formation GO:0035148 25 0.015
multicellular organismal signaling GO:0035637 22 0.015
protein import into nucleus GO:0006606 3 0.015
neuron projection morphogenesis GO:0048812 161 0.015
cellular response to extracellular stimulus GO:0031668 2 0.015
regulation of cell motility GO:2000145 46 0.015
sensory perception of chemical stimulus GO:0007606 3 0.015
cranial nerve development GO:0021545 42 0.015
regulation of cell communication GO:0010646 232 0.015
connective tissue development GO:0061448 99 0.015
regulation of response to stimulus GO:0048583 269 0.015
negative regulation of catabolic process GO:0009895 3 0.015
regulation of gtpase activity GO:0043087 2 0.015
action potential GO:0001508 19 0.014
cognition GO:0050890 1 0.014
regulation of cell death GO:0010941 103 0.014
negative regulation of heart contraction GO:0045822 2 0.014
regulation of ras gtpase activity GO:0032318 2 0.014
peptidyl lysine acetylation GO:0018394 2 0.014
regulation of ph GO:0006885 3 0.014
limb bud formation GO:0060174 2 0.014
convergent extension involved in organogenesis GO:0060029 10 0.014
response to hexose GO:0009746 3 0.014
small gtpase mediated signal transduction GO:0007264 8 0.014
mesenchymal cell differentiation GO:0048762 87 0.014
negative regulation of blood circulation GO:1903523 2 0.014
negative regulation of cellular process GO:0048523 283 0.014
protein targeting to membrane GO:0006612 1 0.014
neural crest cell differentiation GO:0014033 72 0.014
ras protein signal transduction GO:0007265 7 0.014
stem cell development GO:0048864 82 0.014
phagocytosis engulfment GO:0006911 1 0.014
small molecule metabolic process GO:0044281 77 0.014
olfactory lobe development GO:0021988 4 0.014
regulation of cell proliferation GO:0042127 37 0.014
cell differentiation in spinal cord GO:0021515 40 0.014
negative regulation of epithelial cell proliferation GO:0050680 1 0.013
axon guidance GO:0007411 86 0.013
spinal cord motor neuron differentiation GO:0021522 26 0.013
neuron remodeling GO:0016322 1 0.013
heart development GO:0007507 313 0.013
female sex differentiation GO:0046660 4 0.013
golgi vesicle transport GO:0048193 3 0.013
negative regulation of multicellular organismal process GO:0051241 69 0.013
organic substance transport GO:0071702 58 0.013
regulation of cellular component organization GO:0051128 86 0.013
single organism nuclear import GO:1902593 3 0.013
long chain fatty acid transport GO:0015909 1 0.013
fertilization GO:0009566 3 0.013
neural tube formation GO:0001841 16 0.013
death GO:0016265 121 0.013
regulation of response to biotic stimulus GO:0002831 2 0.013
cellular protein modification process GO:0006464 100 0.013
actin cytoskeleton organization GO:0030036 63 0.013
carbohydrate derivative biosynthetic process GO:1901137 43 0.013
regulation of neuron projection development GO:0010975 40 0.013
positive regulation of cell activation GO:0050867 1 0.013
somatic stem cell maintenance GO:0035019 1 0.013
glial cell proliferation GO:0014009 4 0.013
establishment of protein localization to organelle GO:0072594 4 0.013
biological adhesion GO:0022610 40 0.013
response to hormone GO:0009725 48 0.013
negative regulation of signaling GO:0023057 96 0.013
organism emergence from protective structure GO:0071684 4 0.012
positive regulation of developmental process GO:0051094 50 0.012
autonomic nervous system development GO:0048483 19 0.012
lipid storage GO:0019915 1 0.012
positive regulation of transcription dna templated GO:0045893 57 0.012
adult behavior GO:0030534 2 0.012
specification of symmetry GO:0009799 204 0.012
gene expression GO:0010467 252 0.012
regulation of catalytic activity GO:0050790 55 0.012
regulation of protein binding GO:0043393 3 0.012
transmission of nerve impulse GO:0019226 19 0.012
positive regulation of macromolecule metabolic process GO:0010604 93 0.012
regulation of nucleotide catabolic process GO:0030811 2 0.012
hormone secretion GO:0046879 2 0.012
negative regulation of metabolic process GO:0009892 86 0.012
cellular response to steroid hormone stimulus GO:0071383 31 0.012
negative regulation of neuron projection development GO:0010977 9 0.012
positive regulation of nucleotide catabolic process GO:0030813 1 0.012
wnt signaling pathway planar cell polarity pathway GO:0060071 4 0.012
neural crest formation GO:0014029 14 0.012
development of primary female sexual characteristics GO:0046545 4 0.012
peripheral nervous system neuron development GO:0048935 22 0.012
somatic muscle development GO:0007525 4 0.012
fin development GO:0033333 77 0.012
carboxylic acid metabolic process GO:0019752 22 0.012
response to drug GO:0042493 3 0.012
response to endogenous stimulus GO:0009719 83 0.012
membrane invagination GO:0010324 1 0.012
negative regulation of defense response GO:0031348 2 0.012
cell proliferation GO:0008283 80 0.012
cell substrate junction assembly GO:0007044 2 0.012
regulation of locomotion GO:0040012 55 0.012
sensory organ morphogenesis GO:0090596 200 0.012
regulation of cytoskeleton organization GO:0051493 11 0.011
cellular component biogenesis GO:0044085 178 0.011
positive regulation of blood circulation GO:1903524 2 0.011
exocytosis GO:0006887 1 0.011
regulation of wound healing GO:0061041 2 0.011
negative regulation of protein phosphorylation GO:0001933 4 0.011
epithelial cell morphogenesis GO:0003382 2 0.011
cell migration to the midline involved in heart development GO:0003318 12 0.011
cell proliferation in hindbrain GO:0021534 4 0.011
signal transduction in absence of ligand GO:0038034 1 0.011
cellular response to estrogen stimulus GO:0071391 24 0.011
response to transition metal nanoparticle GO:1990267 28 0.011
regulation of gene expression GO:0010468 265 0.011
negative regulation of developmental process GO:0051093 65 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.011
regulation of sequestering of calcium ion GO:0051282 4 0.011
embryonic viscerocranium morphogenesis GO:0048703 52 0.011
glucose homeostasis GO:0042593 1 0.011
regulation of apoptotic process GO:0042981 98 0.011
carbohydrate biosynthetic process GO:0016051 1 0.011
chemotaxis GO:0006935 104 0.011
protein localization to plasma membrane GO:0072659 1 0.011
actin filament based movement GO:0030048 1 0.011
skeletal muscle organ development GO:0060538 78 0.011
inner ear morphogenesis GO:0042472 63 0.011
negative regulation of cellular catabolic process GO:0031330 3 0.011
positive regulation of wound healing GO:0090303 1 0.011
optic nerve morphogenesis GO:0021631 6 0.011
pigmentation GO:0043473 85 0.011
enzyme linked receptor protein signaling pathway GO:0007167 106 0.010
protein modification process GO:0036211 100 0.010
sequestering of calcium ion GO:0051208 3 0.010
wnt signaling pathway GO:0016055 80 0.010
ectodermal placode development GO:0071696 37 0.010
cellular localization GO:0051641 97 0.010
collateral sprouting in absence of injury GO:0048669 4 0.010
heart looping GO:0001947 94 0.010
regulation of stem cell differentiation GO:2000736 4 0.010
negative regulation of protein import into nucleus GO:0042308 2 0.010
nerve development GO:0021675 45 0.010
spinal cord development GO:0021510 46 0.010
regulation of ion transmembrane transporter activity GO:0032412 2 0.010
neuronal action potential GO:0019228 18 0.010
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.010
response to amino acid GO:0043200 2 0.010
tissue regeneration GO:0042246 74 0.010
female gonad development GO:0008585 4 0.010

dixdc1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
physical disorder DOID:0080015 0 0.010
congenital nervous system abnormality DOID:2490 0 0.010